Best Business Services Companies in St. Louis, United States
The 140 best Business Services companies in St. Louis, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: TierPoint.
Ranked: Best Business Services companies in St. Louis
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | TierPoint Provider of IT service suite and data center solutions | $869M | 51 mo ago | Acquired | Patrick Watriss Founder | 2010 | WordPressApple iCloud MailMySQL+24 | — | 1 award |
| 2 | yWhales Provider of blockchain development services | $5M | 44 mo ago | Series A | Mia Murphy Co-Founder | 2021 | — | — | — |
| 3 | Mac Marco Michele Provider of business consulting services | $3M | 26 mo ago | Seed | — | — | — | — | — |
| 4 | One On One Provider of marketing consulting services | $1M | 151 mo ago | Early Stage | David Smith Founder | 1990 | — | — | — |
| 5 | Well Principled Developer of artificial intelligence architecture integrating neuroscience for advanced reasoning | $150K | 72 mo ago | Seed | Chris Shafer Co-Founder | 2018 | — | — | — |
| 6 | nimble Provider of revenue cycle management solutions for surgical clinics | $150K | 199 mo ago | Funding Raised | Nader Samii CEO | 2003 | WordPress Block EditorCart FunctionalityWooCommerce+35 | 12 patents Digital pharmacy validation and remote subscription management platforms for e‑commerce transactions | 1 job opening |
| 7 | Trelus Provides business owners with step-by-step guidance for exit strategies | $100K | 60 mo ago | Seed | Martin Myers CEO | 2018 | — | — | — |
| 8 | Constituent Connection Provider of democracy supporting services | $75K | 31 mo ago | Funding Raised | Spencer Toder Co-Founder | 2021 | — | — | — |
Top 12 Business Services companies in St. Louis
#1
Acquired · St. Louis, Missouri · founded 2010 · 824 employees$869Mraised▾
TierPoint is a provider of IT service suite and data center solutions. It also provides clouds for public, private, and multi-tenant use cases. The features of the product include disaster recovery, network security, data privacy, multi-factor authentication, and encryption, etc. It provides solutions to industries such as healthcare, manufacturing, energy, retail, etc. The clients of the company include Johnsonville, WebsterBank, TommyBahama, etc.
- Mar 2022Series E$500M
- Mar 2020Series D$320M
- 2016Series C—
- Jul 2010Series C$49M
#2
Seed · St. Louis, Missouri$3.1Mraised▾
Provider of business consulting services
#3
Series A · St. Louis, Missouri · founded 2021 · 25 employees$5Mraised▾
Provider of blockchain development services
- Oct 2022Series A$5M
#4
Funding Raised · St. Louis, Missouri · founded 2021 · 6 employees$75Kraised▾
Provider of democracy supporting services
- Nov 2023Grant (prize money)$75K
#5
Early Stage · St. Louis, Missouri · founded 1990$1.4Mraised▾
Provider of marketing consulting services
#6
Seed · St. Louis, Missouri · founded 2018 · 6 employees$150Kraised▾
Developer of artificial intelligence architecture integrating neuroscience for advanced reasoning. This architecture constructs causal world models and generates hypotheses. It adapts to novel situations with minimal training data. The company synthesizes academic research into artificial intelligence solutions. It builds models in fields like electrochemistry, materials science, and metabolism.
- 2020Grant (prize money)$50K
- Aug 2019Seed$150K
#7
Seed · St. Louis, Missouri · founded 2018$100Kraised▾
Provides business owners with step-by-step guidance for exit strategies. It acts as a digital exit roadmap, offering action steps for business owners to follow.
- 2021Seed$100K
#8
Funding Raised · St. Louis, Missouri · founded 2013 · 20 employees$50Kraised▾
Provider of AR/VR development services
- Oct 2021Grant (prize money)$50K
#9
Funding Raised · St. Louis, Missouri · founded 2003 · 237 employees$149.8Kraised▾
Provider of revenue cycle management solutions for surgical clinics. The company offers tech-enabled solutions that allow surgical organizations to streamline their revenue cycle processes, claims matching, staffing challenges, and more.
- Oct 2009Grant (prize money)$149.8K
#10
Seed · St. Louis, Missouri · founded 2018 · 6 employees$50Kraised▾
Cloud-based legislation tracking solution provider. Features include tracking bills & topics, notes on bills, case tracking, real-time legislative alerts, hearing notice management, bill similarity detection management, collaboration management, and etc. The application can be downloaded on iOS and Android platforms.
- Feb 2020Seed$50K
- Nov 2019Grant (prize money)$50K
#11
Acquired · St. Louis, Missouri · founded 1996 · 185 employees—raised▾
Provider of marketing and advertising agency services based in Saint Louis, Missouri. The company's marketing and advertising agency services include brand positioning and messaging, consumer portraits and opportunity maps, advertising evaluation and optimization, innovation, user experience, shopper insight, digital research and global research services, enabling clients to promote their brands through creativity and enhance their business outcomes.
- Jan 2026Unattributed—
- Nov 2018PE—
#12
Late Stage · St. Louis, Missouri · founded 2015 · 50 employees—raised▾
Provider of recruitment services for healthcare sector
- Sep 2025PE—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Business Services coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.