Best Chemicals and Materials Companies in California, United States
The 322 best Chemicals and Materials companies in California, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: amyris.
Our analysis of 50 Chemicals and Materials companies
$3.9b in tracked funding; 74% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Chemicals and Materials companies in California
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | amyris Amyris Biotechnologies specializes in creating renewable products focusing on fuels and chemicals. | $487M | 41 mo ago | 1,598 747 → 1,006 (+35%) | — | WordPressApple iCloud MailMicrosoft 365+20 | Top 5M | 1,124 patents Engineered microbial biosynthesis of cannabinoids, flavors, cosmetics, and specialty chemicals | 1 partnership |
| 2 | Merkle Provider of services in nanotechnology and material research | $303M | 120 mo ago | 2,728 2,728 → 5,633 (+106%) | Andreas Skopal Chief Executive Officer MENA & Dentsu CXM | Adobe Experience ManagerApple iCloud MailMicrosoft 365+24 | Top 1M | 37 patents Data-driven audience segmentation and people-based marketing planning solutions | — |
| 3 | Raydiance Manufacturer of lasers, optical components, and materials | $98M | 131 mo ago | 83 | — | — | — | 66 patents High‑power ultrafast laser machining and precision ablation of brittle/semiconductor materials | — |
| 4 | Rennovia Manufacturer of speciality chemicals | $85M | 106 mo ago | 50 | — | — | — | 245 patents Catalytic conversion of biomass sugars to platform chemicals (HMF, adipic acid) and their purification | — |
| 5 | Yield Engineering Systems Manufacturer of engineering equipment | $55M | 36 mo ago | 122 | Bill Moffat Founder & Co-CEO | Cart FunctionalityWordPressMySQL+23 | Top 50M | — | — |
| 6 | Metara Manufacturer of semiconductors | $44M | 247 mo ago | — | Patrick Franklin Founder | — | — | 30 patents Automated inline chemical analysis and mass spectrometry for process solutions | — |
| 7 | Molten Industries Innovating graphite and hydrogen production for batteries and heavy industry 29Funding top 28%Talent top 28%Patents top 44%Moat bottom 49% All 8 signals ▾Fundingtop 28% Talenttop 28% Patentstop 44% Moatbottom 49% Innovationbottom 48% Techbottom 43% Globalbottom 37% Marketbottom 20% Funding: Raised $25.0M across 4 rounds · 4 rounds over 4 yrs (1.0/yr) Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 29/100 | $25M | 13 mo ago | 6 | Kevin B Co-Founder and CEO | WebflowLeverjQuery+9 | Top 50M | 7 patents Patents concentrated in chemistry & materials | — |
| 8 | Thintronics Developer of insulator technology for high-performance electronics and data transfer | $23M | 22 mo ago | — | Stefan Pastine CEO | — | — | 25 patents Curable polymer films for PCB manufacturing and electronic circuit insulation | 5 job openings · 1 award |
| 9 | Adelphi Technology Manufacturer of high-power neutron sources, neutron generators, and novel radiation detectors 32Funding top 25%Product top 43%Talent top 45%Moat bottom 49% All 8 signals ▾Fundingtop 25% Producttop 43% Talenttop 45% Moatbottom 49% Innovationbottom 41% Patentsbottom 39% Globalbottom 31% Techbottom 18% Funding: Raised $20.0M across 21 rounds · 21 rounds over 5 yrs (4.2/yr) Product: 6 distinct product lines · Company stage: Seed rank vs industry peers · Fliar Intelligence Index 32/100 | $20M | 1 mo ago | — | Charles Gary CEO | — | — | 8 patents Patents concentrated in health & consumer products | — |
| 10 | GC Holdings Develops and manufactures integrated optic platforms and polymers | $20M | 192 mo ago | 51 | — | — | — | — | — |
| 11 | PL&H Developer of a velvet-like coating for aluminum and logo stickers | $17M | 85 mo ago | — | Kamran Qaderi Founder | — | — | — | — |
| 12 | Clean Energy Systems Oxy-fuel technology system developer | $16M | 56 mo ago | 35 | Keith Pronske President and CEO | DudaNginxSnowplow Analytics+12 | Top 50M | — | — |
| 13 | NTS Provider of materials testing and analysis services | $14M | 67 mo ago | 1,400 | — | — | — | — | — |
| 14 | Ammobia Technology solution for ammonia production 27Funding top 30%Talent top 38%Patents top 45%Moat top 47% All 7 signals ▾Fundingtop 30% Talenttop 38% Patentstop 45% Moattop 47% Innovationtop 49% Globalbottom 37% Marketbottom 21% Funding: Raised $11.7M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 27/100 | $12M | 5 mo ago | 3 | Karen Baert Co-Founder & CEO | — | — | 8 patents Patents concentrated in chemistry & materials | 1 partnership · 2 awards |
| 15 | ChromoLogic Provider of bus and minibus rental services with driver options 21Moat top 32%Patents top 36%Funding top 40%Innovation top 41% All 9 signals ▾Moattop 32% Patentstop 36% Fundingtop 40% Innovationtop 41% Producttop 46% Talentbottom 49% Globalbottom 36% Marketbottom 28% Techbottom 15% Moat: Editorial + unicorn rating 4/10 · IP moat: 33 patents Patents: 33 patents matched (strict assignee match) · 9 filings since 2022 vs 8 in 2017-21 rank vs industry peers · Fliar Intelligence Index 21/100 | $11M | 15 mo ago | 19 19 → 31 (+63%) | Naresh Menon Founder & CEO | — | — | 33 patents Patents concentrated in health & consumer products | — |
| 16 | Impossible Metals Manufacturer of battery metals | $10M | 47 mo ago | 24 | Kenneth Nealson Co-Founder | WordPressMySQLPHP+25 | Top 5M | 22 patents Underwater vehicle recovery and deep‑sea mining buoyancy/launch systems | — |
| 17 | LQDX Developer of materials for advanced semiconductor manufacturing processes | $10M | 26 mo ago | — | Simon Mcelrea CEO | — | — | — | — |
| 18 | Aepnus Developer of electrolysis equipment 14Funding top 34%News top 49%Talent bottom 49%Global bottom 37% All 5 signals ▾Fundingtop 34% Newstop 49% Talentbottom 49% Globalbottom 37% Marketbottom 14% Funding: Raised $8.0M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) News: 2 BI events in 12 mo (of 3 tracked, 2 types) · Top themes: Announcements, Funding rank vs industry peers · Fliar Intelligence Index 14/100 | $8M | 4 mo ago | 7 | Bilen Akuzum Co-Founder | — | — | — | — |
| 19 | Maplematerials Developer of technology converting carbon dioxide into graphite anode material | $6M | 22 mo ago | — | Drew Reid Co-Founder & CEO | — | — | — | — |
| 20 | Osomprivacy Online retailer of perfume bases, raw materials, and lab supplies | $5M | 46 mo ago | 7 | — | — | — | — | — |
| 21 | Acreetech Acree Technologies is a research and development firm that offers coating research, development and material… | $4M | 71 mo ago | — | — | — | — | — | — |
| 22 | Dr. Earth Manufactures and supplies probiotic soils and fertilizers | $4M | 70 mo ago | — | Milo Shammas Founder | Cart FunctionalityWooCommerceWordPress+19 | Top 5M | 40 patents Mobile, low-impact diamond core drilling systems for surface mineral exploration | — |
| 23 | PCI Manufacturer of liquid and gaseous oxygen and nitrogen generators for military, medical, industrial, and oil… | $4M | 109 mo ago | 96 | Bob Eng CEO | WordPressMySQLPHP+22 | Top 5M | — | 1 launch |
| 24 | Divimath Designs and develops integrated circuit chips and related materials | $3M | 92 mo ago | — | Carl Zhou Founder | Cart FunctionalityShopifyShop Pay+8 | Top 10M | 2 patents Full-duplex wireless communication systems and protocols | — |
| 25 | Gozen Provider of material transforming services | $3M | 31 mo ago | — | Onur Eren Co-Founder & Board Member | — | — | — | — |
| 26 | Astrileux Manufacturer of IC and semiconductor materials | $3M | 55 mo ago | — | Supriya Jaiswal CEO | — | — | 7 patents Advanced EUV photomask designs with reflective/non‑reflective layer architectures | — |
| 27 | Integrated Surface Technologies. Developer of nano-coating tools and silane coating solutions for devices | $2M | 189 mo ago | — | Jeff Chinn President / CEO | — | — | — | — |
| 28 | Entropy Resins Manufacturer of bio-based epoxy resins for various industrial applications | $2M | 189 mo ago | 2 | Desi Banatao Founder | WordPressCart FunctionalityWooCommerce+31 | Top 5M | — | — |
| 29 | Inlustra Technologies Gallium Nitride (GaN) semiconductor substrates | $2M | 184 mo ago | — | Benjamin Haskell Co-Founder & CEO | — | — | — | — |
| 30 | Toray Advanced Composites Manufacturer of composite and carbon fiber materials 35Funding top 41%Tech top 49%Growth top 50%Talent bottom 49% All 9 signals ▾Fundingtop 41% Techtop 49% Growthtop 50% Talentbottom 49% Marketbottom 46% Globalbottom 36% Productbottom 36% Innovationbottom 24% Newsbottom 21% Funding: Raised $1.2M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Tech: 18 technologies across 4/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 35/100 | $1M | 6 mo ago | 367 | Keisuke Ishii CEO | BootstrapCloudflareSucuri+15 | Top 5M | — | 1 job opening · 1 partnership · 1 expansion |
| 31 | Malama Composites Manufacturer of composites | $896K | 174 mo ago | — | Edward McMahon Co-Founder & COO | — | — | — | — |
| 32 | Lorica International Manufacturer of textiles and yarns | $512K | 144 mo ago | — | — | — | — | 2 patents Fire‑retardant polymer formulations for textile and fabric applications | — |
| 33 | Plasmetex Manufacturer of plastic molding products | $400K | 199 mo ago | — | — | — | — | — | — |
| 34 | Cypris Materials Manufacturer of polymers to provide high-chroma coatings | $375K | 68 mo ago | 10 | Matthew Ryan Co-Founder and CTO | — | — | — | — |
| 35 | Pacific Membranes Manufacturer of polymeric microporous membranes | $320K | 198 mo ago | — | John Simonetti Owner | — | — | — | — |
| 36 | Matregenix Manufacturer of nanofibrous materials | $306K | 45 mo ago | 8 | Sherif Soliman Founder & CEO | HubSpot CMS Hubcore-jsjQuery+15 | Top 10M | 30 patents Patents concentrated in textiles | — |
| 37 | FLO.materials Manufacturer of recycle plastics | $275K | 21 mo ago | — | Kezi Cheng Co-Founder | — | — | — | — |
| 38 | Blue Mountain Minerals Producer of limestone and dolomite minerals | $240K | 185 mo ago | 27 | Jeff Redoutey CEO | WixSentryUIKit+10 | Top 50M | — | — |
| 39 | US Sensor Systems Provider of seismic technology for oilfield monitoring | $200K | 198 mo ago | — | Jim Andersen CEO & President | — | — | — | — |
| 40 | Variance Specialty Finishes Manufacturer of primers and sealers for plaster wall decorative finishes | $200K | 205 mo ago | — | Micah Carroll Co-Founder | — | — | — | — |
| 41 | Vorticity Developer of custom processors | $150K | 81 mo ago | 1 | — | — | — | 15 patents Specialized hardware accelerators (systolic arrays) for high‑performance PDE solving. | — |
| 42 | MARVIN Labs Provider of automated mold and fiber analysis solutions with a focus on DIY mold testing and air quality… | $105K | 54 mo ago | — | Jordan Gruber CEO | — | — | 13 patents Advanced lead‑acid battery components and fluid delivery systems for improved performance | — |
| 43 | 2Dye4 Anodizing Wholesaler of metals and metal ores | $105K | 170 mo ago | — | Joe Osborn Founder | — | — | — | — |
| 44 | Pan Global Brand Self-published content platform | $105K | 193 mo ago | — | — | — | — | — | — |
| 45 | Environmental Institute of America Provider of methyl cellulose and hydroxypropyl methyl cellulose | $100K | 192 mo ago | — | Alex Thatcher CEO | — | — | — | — |
Top 12 Chemicals and Materials companies in California
#1
Seed · Redwood City, California · founded 1986$20Mraised▾
Manufacturer of high-power neutron sources, neutron generators, and novel radiation detectors
- May 2026Seed$2.6M
- Jan 2025Grant (prize money)$1M
- Feb 2023Grant (prize money)$406.5K
- Feb 2023Grant (prize money)$1M
#2
Seed · Oakland, California · founded 2021 · 7 employees$8Mraised▾
Developer of electrolysis equipment
- Feb 2026Seed—
- Jun 2024Seed$8M
- Sep 2023Grant (prize money)$275K
- May 2022Grant (prize money)$150K
#3
Seed · San Francisco, California · founded 2022 · 3 employees$11.7Mraised▾
Technology solution for ammonia production. It uses Haber Bosch solution to produce clean ammonia from clean hydrogen and air.
- Jan 2026Seed$7.5M
- Apr 2024Seed$4.2M
#4
Series A · Oakland, California · founded 2021 · 6 employees$25Mraised▾
Innovating graphite and hydrogen production for batteries and heavy industry. The company advances materials, chemicals, and fuels through innovative technology. They split natural gas into hydrogen and graphite using electrical resistive heating, offering a solution for lithium-ion batteries and heavy industry. Their US-made graphite directly integrates into the battery anode supply chain, reducing environmental impact and cost. The hydrogen production technology delivers hydrogen at cost parity, using less energy than traditional methods. This unlocks potential for industries like steel, heavy transportation, and power generation, enabling shifts towards sustainable practices. They are focused on innovation and sustainability in the energy and industrial sectors.
- Apr 2025Grant (prize money)$5.4M
- Jun 2024Series A$25M
- Apr 2023Grant (prize money)$256K
- Oct 2022Seed—
#5
Funding Raised · Monrovia, California · founded 2007 · 19 employees$10.8Mraised▾
Provider of bus and minibus rental services with driver options. It offers long-term contracts and also provides car rentals with or without a driver. The company has a history of providing transportation services for high-profile events and maintains partnerships with leading tourism companies. Its services cater to both domestic and international tourism sectors.
- Feb 2025Grant (prize money)$3M
- Jun 2022Grant (prize money)$1.1M
- Apr 2021Grant (prize money)$600K
- Apr 2015Grant (prize money)$225K
#6
Funding Raised · Morgan Hill, California · founded 2018 · 367 employees$1.2Mraised▾
Manufacturer of composite and carbon fiber materials
- Dec 2025Grant (prize money)$1.2M
#7
Series A · San Francisco, California · founded 2019$23Mraised▾
Developer of insulator technology for high-performance electronics and data transfer. It optimizes interconnect insulation, enabling high data rates at low power consumption. The company's technology reduces channel loss, delivering low power consumption for high-speed interconnects. It provides solutions for AI data centers, networking, RF microwave, and devices, impacting design for interactive, wearable, and edge AI applications. The company's unified insulator platform spans compute, switching, and networks, reducing loss for RF systems with better connectivity and higher signal quality.
#8
Public · Emeryville, California · founded 2003 · 1598 employees$487.2Mraised▾
Amyris Inc is an industrial biotechnology company. It is engaged in the engineering, manufacturing, and sales of products in a variety of consumer and industrial markets, including cosmetics, flavors and fragrances, solvents and cleaners, polymers, lubricants, healthcare products, and fuels. The business operations are spread across the world with the majority of the revenues generated in the United States. The company generates revenue from the sale of renewable products, licenses of and royalties from intellectual property, and grants, and collaborative research and development services.
#9
Series A · Richmond, California · founded 2019$6.2Mraised▾
Developer of technology converting carbon dioxide into graphite anode material. The company’s process uses electricity to split carbon dioxide into graphite and oxygen. This process aims to be faster, cleaner, and lower cost than traditional graphite production methods. The company focuses on delivering graphitic materials sustainably.
- Aug 2024Series A$6.2M
- Dec 2019Grant (prize money)$225K
- Sep 2019Grant (prize money)$1.1M
- Jun 2019Grant (prize money)$1.1M
#10
Funding Raised · Fremont, California · founded 1980 · 122 employees$55Mraised▾
Yield Engineering Systems specializes in enhancing the speed, reliability, and cost-effectiveness of process engineering equipment through patented technologies. They offer a range of vacuum curing, monolayer coating, and plasma cleaning systems for various applications. The company is known for its lab-to-fab solutions that transform surfaces, materials, and interfaces.
- Jun 2023Conventional Debt$55M
#11
Series A · Santa Clara, California · founded 2007$10Mraised▾
LQDX, formerly known as Averatek, is a Santa Clara-based developer of materials for advanced semiconductor manufacturing that recently raised $10M in Equity and Government funding. The company focuses on the rapid adoption of its Artificial Intelligence enabling chemistries and processes.
- Apr 2024Series A$10M
#12
Acquired · Palo Alto, California · founded 1971 · 2728 employees$302.8Mraised▾
Provider of services in nanotechnology and material research
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Chemicals and Materials coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Advanced Materials in California is moving
A read on the academic research around Advanced Materials in California — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 90 papers.
UC Los Angeles, Berkeley, and Irvine lead California's optimistic advanced-materials research, predominantly exploring mechanics, sensor/energy-harvesting materials, and self-healing polymer composites across 90 papers.
- University of California, Los Angeles19
- University of California, Berkeley15
- University of California, Irvine12
- California Institute of Technology10
- University of California San Diego7
- Smart material5→12
- Actuator1→4
- Piezoelectricity1→3
- Nanotechnology4→6
- Polymer4→5
- Actuator2→4
- Nanotechnology1→3
- Smart material3→4
- Smart material3
- Morphing2
- Soft robotics2
- Nanotechnology2
- 3D printing2