Best Chemicals and Materials Tech Companies in Ohio, United States
The 42 best Chemicals and Materials Tech companies in Ohio, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Locus FS.
Our analysis of 50 Chemicals and Materials Tech companies
$4.4b in tracked funding; 79% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Chemicals and Materials Tech companies in Ohio
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Stage | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Locus FS Bio-based solutions enhancing performance across agriculture, industrial, mining, and oil & gas 67Funding top 20%Patents top 23%Innovation top 32%Growth top 35% All 9 signals ▾Fundingtop 20% Patentstop 23% Innovationtop 32% Growthtop 35% Moattop 35% Newstop 40% Techtop 45% Marketbottom 49% Globalbottom 42% Funding: Raised $250M across 2 rounds · 2 rounds over 3 yrs (0.7/yr) Patents: 556 patents matched (strict assignee match) · 220 filings since 2022 vs 330 in 2017-21 rank vs industry peers · Fliar Intelligence Index 67/100 | $250M | 8 mo ago | 163 | — | WordPressMySQLPHP+27 | Series B | 556 patents Patents concentrated in chemistry & materials | 1 job opening |
| 2 | BiOWiSH Biotechnology solutions for agriculture, aquaculture, and environmental management industries | $40M | 36 mo ago | 32 | — | WordPressMySQLPHP+27 | Series B | 29 patents Microbial feed additives and water‑treatment formulations for alcohol mitigation, cyanuric acid removal, and denitrification. | — |
| 3 | Locus AG Provider of agricultural biologicals for row crops, fruits, vegetables, and more | $29M | 75 mo ago | — | — | WordPressMySQLPHP+16 | Series B | 556 patents Bio-based industrial biotech and data-driven predictive information system platforms | — |
| 4 | Felux Online B2B marketplace and logistics service provider for the steel industry | $25M | 50 mo ago | 36 | Chris Day Co-Founder & COO | Node.jsVuetifyVue.js+10 | Series A | — | — |
| 5 | Angstron Materials Graphene innovator providing advanced materials and battery solutions | $14M | 100 mo ago | 27 | — | — | Series A | — | — |
| 6 | EcoScraps Gardening solutions: soils, plant food, care, and organic options | $12M | 142 mo ago | 11 | — | — | Series B | — | — |
| 7 | ParaGen Technologies Developer of tissue engineering technologies | $12M | 57 mo ago | 16 | Flavio Lobato Co-Founder | — | Series A | — | — |
| 8 | Global Graphene Group Manufacturer of graphene-based materials and battery components | $10M | 122 mo ago | 36 | Bor Jang Co-Founder & CEO | — | Public | 505 patents Patents concentrated in electrical & electronics | — |
| 9 | OCO Manufacturer of green formic acid 8Moat top 48%Funding top 50%Tech bottom 42%Global bottom 36% All 6 signals ▾Moattop 48% Fundingtop 50% Techbottom 42% Globalbottom 36% Newsbottom 21% Marketbottom 19% Moat: Editorial + unicorn rating 4/10 · 9 curated direct competitors tracked Funding: Raised $5.8M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 8/100 | $6M | 8 mo ago | 4 | — | WordPressMySQLPHP+17 | Seed | — | 1 award |
| 10 | General Nano Manufacturer of lightweight, conductive, multi functional materials using carbon nanotubes | $4M | 50 mo ago | 14 | — | — | Series A | 41 patents Conductive nanocomposite materials for lightning protection, EMI shielding, and repair applications | — |
| 11 | Inorganic Specialists Manufacturers of CNT papers | $4M | 199 mo ago | — | David Firsich Founder | — | Deadpooled | 8 patents Silicon‑enhanced nanofiber anodes and carbon nanofiber paper for high‑performance lithium batteries | — |
| 12 | OsteoNovus Provider of biomimetic materials to support and regenerate bone | $4M | 71 mo ago | 9 | Sarit Bhaduri Dfacers Faimbe Fnai Co-Founder and Board Member | — | Seed | 7 patents Spherical calcium phosphate granules for bone and dental regeneration applications | — |
| 13 | Matrix Food Technologies Provider of plant-based alternative proteins for meat | $3M | 68 mo ago | 10 | Jed Johnson Co-Founder and CTO | — | Acquired | — | — |
| 14 | Nanotek Instruments Graphene innovator providing advanced materials and battery solutions | $3M | 177 mo ago | — | Aruna Zhamu Co-Founder & CTO | — | Funding Raised | 929 patents Graphene‑enhanced electrode materials for high‑performance lithium and metal‑sulfur batteries | — |
| 15 | 3Bar Biologics Provider of microbe-based crop nutrition products | $3M | 47 mo ago | 13 13 → 23 (+77%) | — | — | Seed | 12 patents Microbial inoculant delivery systems for enhancing plant growth and agricultural yields. | — |
| 16 | Aropha Provider of robotics & AI advancing biodegradability testing & material development services | $2M | 28 mo ago | — | Travis Johnston Co-Founder | WordPressApple iCloud MailMySQL+31 | Seed | — | — |
| 17 | Nanofiber Solutions 3D nanofiber scaffolds for regenerative medicine, veterinary, and cell culture | $2M | 85 mo ago | 8 | — | — | Funding Raised | 118 patents Nanofiber biomedical scaffolds for tissue engineering, drug delivery, electroporation, and cultured meat | — |
| 18 | SCI Engineered Materials Supplier and manufacturer of advanced materials for PVD Thin Film applications | $1M | 203 mo ago | 23 23 → 24 (+4%) | Edward Funk Co-Founder | WordPressMySQLPHP+25 | Public | — | — |
| 19 | ZeoVation Supplier of antimicrobial and zeolite particle technology. | $780K | 17 mo ago | 4 | Bo Wang Co-Founder | — | Seed | 4 patents Zeolite-based antimicrobial agents for biofilm, virus, and fungal control on surfaces | — |
| 20 | Nodis Smart glass manufacturer | $500K | 71 mo ago | 7 | Sergey Shokhor Co-Founder & Co-CEO | — | Seed | — | — |
| 21 | Tesla NanoCoatings Protective nanocoatings for fighting corrosions | $100K | 171 mo ago | 8 | — | WordPressMySQLPHP+26 | Seed | 89 patents Advanced nanocoatings for corrosion resistance, slip resistance, and functionalized graphene surfaces. | — |
Top 12 Chemicals and Materials Tech companies in Ohio
#1
Series B · Solon, Ohio · founded 2014 · 163 employees$250Mraised▾
Bio-based solutions enhancing performance across agriculture, industrial, mining, and oil & gas. They specialize in high-performance intermediary formulations using glycolipids and microbes to surpass conventional chemistry. Their solutions enhance soil quality, nutrient uptake, crop production, recovery, stimulation, flow assurance, metal extraction, mineral extraction, and product performance while reducing chemical usage. They offer formulated ingredients designed for various industries, providing bio-enhanced solutions that are easy to adopt and cost-effective. They focus on sustainability, delivering eco-friendly benefits without compromising efficacy. Their proprietary platform merges biology, technology, and manufacturing to deliver high-efficiency ingredients via intermediates that outperform conventional chemicals. They provide hands-on technical expertise and support, offering custom, high-performance bio-based solutions to solve formulation challenges.
- Dec 2025Series B$20M
- Apr 2023Conventional Debt$117M
#2
Seed · Oregon, Ohio · founded 2018 · 4 employees$5.8Mraised▾
Manufacturer of green formic acid. It provides solutions to capture and convert carbon into useful products using electrolysis technology. It develops an electrolyzer device that binds CO2 with the hydrogen available in the water to develop organic formate in energy-dense stable and non-flammable liquid form. It can transforms and stores electric energy into chemical energy.
- Dec 2025Seed$2.1M
- Nov 2023Seed$5M
- Apr 2022Grant (prize money)$1.5M
- Jul 2021Grant (prize money)$239.9K
#3
Seed · Columbus, Ohio · founded 2016 · 4 employees$780Kraised▾
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- Mar 2025Grant (prize money)$1.2M
- Sep 2020Grant (prize money)$1M
- Jul 2019Seed$220K
- Feb 2019Grant (prize money)$250K
#4
Series B · Cincinnati, Ohio · founded 2007 · 32 employees$39.6Mraised▾
Biotechnology solutions for agriculture, aquaculture, and environmental management industries. We provide innovative biotechnology solutions, working with key officials and institutions globally to understand customer needs and develop solutions that fit current practices. We focus on delivering scientifically proven solutions for modern agriculture and environmental sustainability. Our offerings improve soil health, crop yields, and aquaculture practices. We are dedicated to creating resilient, regenerative agriculture systems that nourish both people and the planet. We lead the transition to biologically enhanced efficiency fertilizers, collaborating with the fertilizer industry to increase crop production sustainably, economically, and with a reduced carbon footprint. Our technology is natural and non-GMO, safe for people, plants, and animals, driving the future of biological solutions.
- Aug 2023Conventional Debt$2M
- Jul 2022Series B$5M
- Aug 2018Series B$7.5M
- Sep 2017Series B$2.1M
#5
Series A · Cleveland, Ohio · founded 2018 · 36 employees$24.6Mraised▾
Online B2B marketplace and logistics service provider for the steel industry. It allows users to connect, and manage sourcing, procurement, financing, and shipping. The platform enables tracking orders in real-time and getting access to the transportation network.
- Jun 2022Series A$19.5M
- Aug 2021Seed$5.1M
#6
Seed · Cleveland, Ohio · founded 2021$2.2Mraised▾
Provider of robotics & AI advancing biodegradability testing & material development services
- Apr 2024Seed$1M
- Mar 2024Seed$1.2M
#7
Series B · Solon, Ohio · founded 2015$29.3Mraised▾
Provider of agricultural biologicals for row crops, fruits, vegetables, and more. These biologicals are proven by third-party trials to increase yields. The company's specially formulated biologicals help farmers get more out of their fertilizer. They also improve soil quality, enhance nutrient uptake, and increase plant vigor. The company offers liquid inoculants and products with beneficial bacteria and fungus.v
- May 2020Series B$20.3M
- Aug 2018Series A$9.1M
- Aug 2018Conventional Debt$11.3M
#8
Series A · Columbus, Ohio · founded 2016 · 16 employees$11.6Mraised▾
ParaGen Technologies is involved in developing tissue engineering technologies. They have developed their own synthetic nanofiber scaffolds, which replicates the extracellular matrix and enables healing by mimicking the physical structures present naturally in our body. Their technology can be used for wound care, orthopedics, vascular, and hernia repair.
- Nov 2021Series A$4.4M
- Apr 2019Seed$3.1M
- Nov 2018Conventional Debt$3M
- Dec 2017Seed$4.1M
#9
Seed · Columbus, Ohio · founded 2013 · 13 employees$2.8Mraised▾
Provider of microbe-based crop nutrition products. It has developed a biological solution that can be used through an in-furrow drip system or as a seed inoculant. The solution comes in packings. Farmers need to uncap the packing, after which bacterias in the solution are activated. Its solution protects the plants against many pathogens and increases productivity.
- Sep 2022Grant (prize money)$650K
- Jul 2021Grant (prize money)$100K
- Nov 2020Seed$780K
- Sep 2017Grant (prize money)$600K
#10
Series A · Cincinnati, Ohio · founded 2008 · 14 employees$4.2Mraised▾
Manufacturer of lightweight, conductive, multi-functional materials using carbon nanotubes. It offers products for aircraft, rotorcraft, aerial vehicles, satellites, and missiles under its brand name. The product line includes black-body calibration, flexible heating, and lightning strike protection.
#11
Series B · Marysville, Ohio · founded 2010 · 11 employees$11.9Mraised▾
Gardening solutions: soils, plant food, care, and organic options. This company provides a comprehensive range of gardening and plant care products. They offer soils, plant food, and solutions for plant care, including organic options. The company supports gardeners with resources like gardening basics, how-to guides, and project planning for various spaces. They provide products for growing flowers, fruits, herbs, succulents, and vegetables. The company emphasizes water-wise gardening and community engagement. They offer a shop, cart, login, and support services, including order status and a guarantee. The company focuses on providing quality products and resources for successful gardening experiences.
- Oct 2014Conventional Debt$315K
- Jul 2014Series B$6.6M
- Nov 2013Series A$1.2M
- Apr 2013Series A$2.6M
#12
Series A · Dayton, Ohio · founded 2007 · 27 employees$13.7Mraised▾
Graphene innovator providing advanced materials and battery solutions. The company specializes in graphene production and its application in various industries. They offer graphene in powder form and nano-intermediates, along with thermal management solutions like heat spreaders. Their expertise extends to graphene-enabled silicon anodes, paints, coatings, and lithium metal battery solutions, including graphene-protected lithium metal electrodes and fire-resistant products. They provide technical services and focus on research and development for graphene-enabled applications. The company is an IP leader in solid-state batteries, with scalable processes for graphene oxide and reduced graphene oxide. They offer highly conductive intermediate products for electronic end markets and corrosion-inhibiting coating materials. Their offerings cater to diverse sectors, including electronics and energy storage, with a focus on enhancing performance and safety through graphene technology.
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Chemicals and Materials Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
What Ohio researches in advanced materials
- The Ohio State University24
- Ohio Aerospace Institute1