Best Chemicals Tech Companies in United States
The 509 best Chemicals Tech companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Indigo.
Tracking the strongest Chemicals Tech companies in the United States, this directory covers 509 ventures with $8.6B in total disclosed funding, ranked by equity raised and recent momentum. That's a serious capital base. The global chemicals market sat at roughly $6,851.6B in 2023 and is growing at a 7.8% CAGR, pulled forward by manufacturing advances, packaging technology, and economies running at fuller capacity. Four unicorns have emerged from this cohort, which tells you the ceiling here isn't low.
LanzaTech leads our tracked companies at $869M raised, with Locus FS at $250M and Osmo at $65M rounding out the upper tier. So where's the heat right now? EV battery chemistry and next-generation powertrain materials are the themes I keep seeing dominate new raises, and median app-install growth of roughly 14% year-over-year across 17 chemicals-focused platforms confirms that digital tooling around the sector is accelerating too. The most active backers, National Science Foundation, DOE, and America's Seed Fund, skew toward deep-science bets, which explains why the funding mix leans technical. If you're benchmarking a chemicals tech company today, this list is where to start.
- MarketsandMarkets
Ranked: Best Chemicals Tech companies in United States
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Market signals (1y) | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Indigo 🦄 Provider of biological and sustainability solutions for the agriculture industry | $1.4B | 33 mo ago | 708 708 → 1,393 (+97%) · sector median +45% | Geoffrey Maltzahn Co-Founder | HubSpot CMS HubApple iCloud MailSalesforce+35 | — | 355 patents Patents concentrated in health & consumer products | 1 partnership |
| 2 | LanzaTech 🦄 Developer of technology converting carbon-rich gases into fuels and chemicals 78Patents top 10%Funding top 17%News top 25%Innovation top 26% All 13 signals ▾Patentstop 10% Fundingtop 17% Newstop 25% Innovationtop 26% Moattop 26% Producttop 29% Markettop 30% Talenttop 34% Partnerstop 35% Techtop 36% Globaltop 37% Growthtop 45% Fin. healthbottom 48% Patents: 765 patents matched (strict assignee match) · 530 filings since 2022 vs 213 in 2017-21 Funding: Raised $869M across 21 rounds · 21 rounds over 21 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 78/100 | $869M | 4 mo ago | 367 367 → 243 (-34%) · sector median +45% | Sean Simpson Co-Founder | DrupalPHPSalesforce+32 | 25 signals ▲56% Funding · Hiring · Leadership | 765 patents Industrial gas fermentation using engineered microbes to convert C1 gases into chemicals and proteins | 2 partnerships · 1 expansion · 1 award |
| 3 | Solugen 🦄 Developer of industrial solutions for oil and gas, fuels, and defense | $637M | 43 mo ago | 99 | Sean Hunt Co-Founder & CTO | WordPressMySQLPHP+26 | — | 210 patents Patents concentrated in chemistry & materials | — |
| 4 | Pivot Bio 🦄 Developer of microbial nitrogen products designed for crop nutrition enhancement | $618M | 58 mo ago | 256 256 → 305 (+19%) · sector median +45% | Alvin Tamsir Co-Founder & Chief Science Officer | WordPressApple iCloud MailMicrosoft 365+36 | — | 346 patents Engineered nitrogen‑fixing microbes and formulations for sustainable crop nitrogen delivery | 2 awards |
| 5 | Genomatica Manufacturer of plant-based nylon materials and renewable chemicals 62Product top 18%Patents top 20%Funding top 26%Moat top 26% All 11 signals ▾Producttop 18% Patentstop 20% Fundingtop 26% Moattop 26% Innovationtop 30% Talenttop 38% Markettop 43% Growthtop 45% Globalbottom 46% Techbottom 37% Newsbottom 32% Product: 4 distinct product lines · Company stage: Series F Patents: 1,721 patents matched (strict assignee match) · 424 filings since 2022 vs 633 in 2017-21 rank vs industry peers · Fliar Intelligence Index 62/100 | $388M | 58 mo ago | 153 153 → 230 (+50%) · sector median +45% | Bernhard Palsson Co-Founder | — | — | 1,721 patents Engineered microbial production of renewable chemicals like fatty acids, diamines, and glycol derivatives | — |
| 6 | Locus FS Bio-based solutions enhancing performance across agriculture, industrial, mining, and oil & gas 67Funding top 20%Patents top 23%Innovation top 32%Growth top 35% All 9 signals ▾Fundingtop 20% Patentstop 23% Innovationtop 32% Growthtop 35% Moattop 35% Newstop 40% Techtop 45% Marketbottom 49% Globalbottom 42% Funding: Raised $250M across 2 rounds · 2 rounds over 3 yrs (0.7/yr) Patents: 556 patents matched (strict assignee match) · 220 filings since 2022 vs 330 in 2017-21 rank vs industry peers · Fliar Intelligence Index 67/100 | $250M | 6 mo ago | 163 | — | WordPressMySQLPHP+27 | — | 556 patents Patents concentrated in chemistry & materials | 2 job openings · 1 launch |
| 7 | Anuvia Plant Nutrients Premier online football betting platform with comprehensive leagues and diverse options | $247M | 50 mo ago | 92 | Jeffrey Burnham Founder | — | — | 47 patents Controlled-release coated fertilizers integrating high-value organics and bioactive additives | — |
| 8 | Vestaron Revolutionizing crop protection with peptide technology for sustainable agriculture 62Funding top 17%Product top 18%Patents top 19%Innovation top 26% All 11 signals ▾Fundingtop 17% Producttop 18% Patentstop 19% Innovationtop 26% Moattop 26% Techtop 35% Growthtop 45% Talentbottom 49% Globalbottom 42% Marketbottom 41% Newsbottom 24% Funding: Raised $204M across 18 rounds · 18 rounds over 19 yrs (0.9/yr) Product: 4 distinct product lines · Company stage: Series F rank vs industry peers · Fliar Intelligence Index 62/100 | $204M | 16 mo ago | 54 | Juan Estupinan CEO and President | WordPressBugHerdMySQL+37 | — | 225 patents Peptide-based bioinsecticides—engineered toxin peptides for agricultural pest control. | — |
| 9 | Provivi Developer of agricultural solutions designed to protect crops from insect damage 60Funding top 17%Patents top 24%Moat top 26%Innovation top 34% All 10 signals ▾Fundingtop 17% Patentstop 24% Moattop 26% Innovationtop 34% Talenttop 38% Growthtop 39% Marketbottom 44% Globalbottom 44% Techbottom 37% Newsbottom 22% Funding: Raised $185M across 13 rounds · 13 rounds over 13 yrs (1.0/yr) Patents: 158 patents matched (strict assignee match) · 64 filings since 2022 vs 89 in 2017-21 rank vs industry peers · Fliar Intelligence Index 60/100 | $185M | 8 mo ago | 83 83 → 83 (+0%) · sector median +45% | Frances Arnold Co-Founder | Node.jsMUIOpenSSL+10 | — | 158 patents Bio-based synthesis and microbial production of insect pheromones for sustainable pest control | 1 partnership |
| 10 | NewLeaf Symbiotics Developer of biological technologies for improved crop input performance | $181M | 30 mo ago | 35 35 → 49 (+40%) · sector median +45% | Stephen Kahn Co-Founder | WordPressMySQLPHP+24 | — | 300 patents Microbial fermentation and biocontrol formulations for plant health and methane mitigation | — |
| 11 | Forge Nano Manufacturer of atomic layer deposition equipment and related coated materials 67Funding top 18%Patents top 18%Product top 21%Innovation top 24% All 11 signals ▾Fundingtop 18% Patentstop 18% Producttop 21% Innovationtop 24% Moattop 28% Talenttop 34% Growthtop 43% Techtop 44% Globalbottom 42% Marketbottom 41% Newsbottom 38% Funding: Raised $162M across 14 rounds · 14 rounds over 11 yrs (1.3/yr) Patents: 72 patents matched (strict assignee match) · 49 filings since 2022 vs 22 in 2017-21 rank vs industry peers · Fliar Intelligence Index 67/100 | $162M | 13 mo ago | 65 65 → 124 (+91%) · sector median +45% | Paul Lichty Co-Founder & CEO | WordPressMySQLPHP+23 | 3 signals ▼50% Funding · IPO | 72 patents Advanced atomic layer deposition for high-performance energy storage and conversion components | — |
| 12 | Knowde Provider of a platform for chemical industry data management solutions | $146M | 22 mo ago | 118 | Ali Javaheri Co-Founder & CEO | WordPress Block EditorWordPressApple iCloud Mail+26 | — | — | — |
| 13 | Manus Bio Developer of phytochemicals using microbial fermentation | $125M | 36 mo ago | 104 | Gregory Stephanopoulos Co-Founder | WebflowApple iCloud MailMicrosoft 365+12 | — | — | 4 job openings · 3 launchs |
| 14 | Syzygy Plasmonics Developer of technology for sustainable aviation fuel, methanol, syngas, and hydrogen | $116M | 32 mo ago | 101 | Peter Nordlander Co-Founder | — | 3 signals ▲200% Contracts | 99 patents Patents concentrated in transport & manufacturing processes | — |
| 15 | actnano Provider of nanocoatings for diversified applications 62Patents top 24%Moat top 25%Funding top 26%Innovation top 27% All 10 signals ▾Patentstop 24% Moattop 25% Fundingtop 26% Innovationtop 27% Growthtop 31% Techtop 49% Marketbottom 43% Newsbottom 42% Globalbottom 42% Talentbottom 40% Patents: 54 patents matched (strict assignee match) · 49 filings since 2022 vs 5 in 2017-21 Moat: Editorial + unicorn rating 7/10 · IP moat: 54 patents rank vs industry peers · Fliar Intelligence Index 62/100 | $82M | 20 mo ago | 45 45 → 98 (+118%) · sector median +45% | Taymur Ahmad Founder and CEO | WordPressMySQLPHP+26 | — | 54 patents Low-friction, anti-fog zwitterionic hydrogel and polymer coating technologies. | — |
| 16 | Citrine Informatics Provider of AI-based solutions for materials informatics 55Funding top 24%AI top 24%Product top 30%Moat top 31% All 12 signals ▾Fundingtop 24% AItop 24% Producttop 30% Moattop 31% Patentstop 33% Innovationtop 39% Talentbottom 49% Techbottom 48% Growthbottom 44% Globalbottom 42% Marketbottom 39% Newsbottom 24% Funding: Raised $78.7M across 12 rounds · 12 rounds over 10 yrs (1.2/yr) AI: Holds AI/ML patents (G06N-family CPC) · Product described with: ai-based, machine learning rank vs industry peers · Fliar Intelligence Index 55/100 | $79M | 12 mo ago | 53 53 → 68 (+28%) · sector median +45% | Greg Mulholland Co-Founder & CEO | WordPressMySQLPHP+23 | — | 20 patents AI-driven materials formulation and design optimization for chemicals and polymers | 1 job opening · 1 launch · 2 partnerships |
| 17 | Kula Bio Manufacturer of microbial crop nutrition products 35Funding top 23%Talent top 28%Moat top 31%Global bottom 37% All 6 signals ▾Fundingtop 23% Talenttop 28% Moattop 31% Globalbottom 37% Marketbottom 28% Newsbottom 22% Funding: Raised $71.2M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) Talent: Analyst team rating 5/5 · 2 named leaders on record rank vs industry peers · Fliar Intelligence Index 35/100 | $71M | 7 mo ago | 12 | Bill Brady Co-Founder & CEO | — | — | — | — |
| 18 | Osmo AI-based fragrance digitization system 62Funding top 22%Moat top 24%AI top 26%News top 27% All 10 signals ▾Fundingtop 22% Moattop 24% AItop 26% Newstop 27% Growthtop 35% Talenttop 38% Partnerstop 45% Techbottom 46% Marketbottom 38% Globalbottom 36% Funding: Raised $65.0M across 4 rounds · 4 rounds over 3 yrs (1.3/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 62/100 | $65M | 4 mo ago | 28 | Rohinton Mehta Co-Founder & Head of Business Development and Data Operations | WebflowApple iCloud MailGoogle Workspace+13 | 4 signals Funding · Capital raise | — | 3 job openings · 1 partnership |
| 19 | BioConsortia Developer of microbial-based solutions for nitrogen fixation, disease, and nematode control | $56M | 26 mo ago | 46 | — | WordPressMySQLPHP+16 | — | 223 patents Patents concentrated in health & consumer products | 1 launch · 1 partnership |
| 20 | Lygos Manufacturer of green acids from microbes 64Moat top 26%Patents top 27%Funding top 30%Growth top 31% All 9 signals ▾Moattop 26% Patentstop 27% Fundingtop 30% Growthtop 31% Innovationtop 33% Techtop 40% Talentbottom 49% Marketbottom 48% Globalbottom 42% Moat: Editorial + unicorn rating 8/10 · IP moat: 111 patents Patents: 111 patents matched (strict assignee match) · 56 filings since 2022 vs 49 in 2017-21 rank vs industry peers · Fliar Intelligence Index 64/100 | $52M | 14 mo ago | 63 | Eric Steen CEO & Co-founder | Builder.ioApple iCloud MailGoogle Workspace+21 | — | 111 patents Patents concentrated in chemistry & materials | — |
| 21 | DMC Manufacturer of bio-based specialty chemicals 53Funding top 21%Patents top 21%Product top 25%Innovation top 28% All 10 signals ▾Fundingtop 21% Patentstop 21% Producttop 25% Innovationtop 28% Moattop 32% Talenttop 33% Globalbottom 44% Techbottom 38% Marketbottom 35% Newsbottom 21% Funding: Raised $47.8M across 12 rounds · 12 rounds over 9 yrs (1.3/yr) Patents: 38 patents matched (strict assignee match) · 27 filings since 2022 vs 11 in 2017-21 rank vs industry peers · Fliar Intelligence Index 53/100 | $48M | 6 mo ago | 24 24 → 41 (+71%) · sector median +45% | Matt Lipscomb ex-Co-Founder | — | — | 38 patents Metal cladding and friction‑stir additive manufacturing for heat‑exchanger tubesheets | 2 job openings |
| 22 | NanoTech Materials Provider of roof coating, fireproofing, insulation, and custom formulation 48Tech top 26%Funding top 35%Talent top 38%News top 40% All 10 signals ▾Techtop 26% Fundingtop 35% Talenttop 38% Newstop 40% Growthtop 45% Producttop 46% Innovationbottom 46% Moatbottom 38% Marketbottom 36% Globalbottom 32% Tech: 41 technologies across 6/8 capability areas · Cloud: Cloudflare Funding: Raised $43.7M across 3 rounds · 3 rounds over 6 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $44M | 2 mo ago | — | Hani Taan Chief Technology Officer & Co-Founder | Node.jsNextAuth.jsTailwind CSS+21 | 3 signals Funding · New product | — | — |
| 23 | Novaphos Provider of sustainable phosphoric acid production technology | $40M | 20 mo ago | 5 | Joseph Megy Founder & CTO | — | — | 29 patents Phosphorus manufacturing processes and calcium silicate production technologies | — |
| 24 | Mstack AI Developer of AI platform for chemical synthesis and manufacturing solutions | $40M | 20 mo ago | — | Shreyans Chopra Founder & CEO | Tailwind CSSAmazon Web ServicesGoogle Workspace+5 | — | — | 1 launch |
| 25 | P2 Science Manufacturer of diversified green chemicals 60Patents top 21%Funding top 27%Innovation top 28%Talent top 28% All 11 signals ▾Patentstop 21% Fundingtop 27% Innovationtop 28% Talenttop 28% Moattop 29% Producttop 34% Growthtop 35% Techtop 46% Globalbottom 44% Newsbottom 32% Marketbottom 30% Patents: 245 patents matched (strict assignee match) · 102 filings since 2022 vs 115 in 2017-21 Funding: Raised $39.2M across 8 rounds · 8 rounds over 15 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 60/100 | $39M | 0 mo ago | 19 19 → 40 (+111%) · sector median +45% | Patrick Foley President and Co-Founder | Cart FunctionalityWooCommerceWordPress+31 | — | 245 patents Specialty polymer surfactants and cosmetic ingredients, plus ozonolysis synthesis of dicarboxylic acids | 1 job opening · 1 launch · 2 awards |
| 26 | NanoSonic Nanomaterial innovator specializing in sensors, additive manufacturing, and polymer design 22Funding top 35%Talent top 39%AI top 45%Market bottom 30% All 6 signals ▾Fundingtop 35% Talenttop 39% AItop 45% Marketbottom 30% Globalbottom 29% Techbottom 15% Funding: Raised $30.5M across 31 rounds · 31 rounds over 20 yrs (1.6/yr) Talent: Analyst team rating 4/5 · 1 named leader on record rank vs industry peers · Fliar Intelligence Index 22/100 | $31M | 6 mo ago | 25 | Richard Claus Founder & CEO | — | — | — | — |
| 27 | Switch Bioworks Developer of microbial solutions for sustainable on-site fertilizer production | $27M | 17 mo ago | 21 | — | Cart FunctionalitySquarespace CommerceSquarespace+14 | — | 5 patents Synthetic biology microbial gene switches for density and phosphate sensing, plus irreversible condition control | 1 launch |
| 28 | Zymochem Provider of engineered microbes and biosynthetic pathways for industrial chemicals | $25M | 13 mo ago | 35 | Harshal Chokhawala Co-Founder & CEO | Cart FunctionalitySquarespace CommerceSquarespace+14 | — | 42 patents Sustainable absorbent polymer production and renewable‑source chemical synthesis technologies. | — |
| 29 | Kebotix AI solutions for materials discovery | $24M | 22 mo ago | 12 | Jill Becker CEO | — | — | 24 patents AI-driven molecular property prediction and automated synthesis for functional organic materials | — |
| 30 | Trillium Renewable Chemicals Manufacturer of green acrylonitrile and acetonitrile from biorenewable feedstocks 19Funding top 29%Moat top 48%Talent bottom 49%Global bottom 38% All 6 signals ▾Fundingtop 29% Moattop 48% Talentbottom 49% Globalbottom 38% Newsbottom 33% Marketbottom 23% Funding: Raised $21.9M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) Moat: Editorial + unicorn rating 5/10 · 9 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 19/100 | $22M | 1 mo ago | 3 | Corey Tyree Founder & CEO | — | — | — | — |
| 31 | Still Bright Developer of precious metal catalysts | $19M | 10 mo ago | 5 | Jon Vardner Co-Founder & CEO | — | — | — | 3 job openings · 1 expansion |
| 32 | Allvivo Vascular Developing antimicrobial solutions for medical devices and wound-related infections | $18M | 12 mo ago | — | Jennifer Neff Chief Executive Officer | — | — | 25 patents Cationic drug delivery via adhesive films and antimicrobial wound‑care constructs. | — |
| 33 | Q-Chem Developer of quantum chemistry software for accurate molecular system modeling | $15M | 14 mo ago | 52 | Peter Gill Founder | DrupalPHPUbuntu+11 | — | 205 patents DNA-encoded library synthesis and screening for drug discovery compounds | 1 internship · 6 launchs |
| 34 | Ruby Bio Provider of naturally occurring yeast services for food & beverage and personal & healthcare industry | $13M | 13 mo ago | 10 | Charlie Silver CEO | — | — | — | 1 partnership |
| 35 | Pyran Developer of technology producing bio-based alternatives to petroleum-derived products | $12M | 20 mo ago | 8 | Kevin Barnett Co-Founder | — | — | — | — |
| 36 | Caravel Bio Developer of a platform for directed evolution of biomolecules and enzymes 13Talent top 38%Funding top 39%Tech bottom 39%Global bottom 33% All 5 signals ▾Talenttop 38% Fundingtop 39% Techbottom 39% Globalbottom 33% Marketbottom 13% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $10.0M across 3 rounds · 3 rounds over 2 yrs (1.5/yr) rank vs industry peers · Fliar Intelligence Index 13/100 | $10M | 8 mo ago | 2 | Trevor Nicks Founder & CEO | Cart FunctionalitySquarespace CommerceSquarespace+12 | — | — | 1 partnership |
| 37 | Aptamatrix Developer of next generation technology based diagnostic tools | $9M | 14 mo ago | 6 | Philip Borer Co-Founder & President | — | — | — | — |
| 38 | Sylvatex Developer of advanced materials for energy, industrial, and strategic applications 27Moat top 38%Funding top 40%Patents top 44%Innovation top 46% All 10 signals ▾Moattop 38% Fundingtop 40% Patentstop 44% Innovationtop 46% Producttop 46% Talentbottom 49% Techbottom 46% Globalbottom 37% Marketbottom 26% Newsbottom 21% Moat: Editorial + unicorn rating 4/10 · IP moat: 23 patents Funding: Raised $8.4M across 6 rounds · 6 rounds over 15 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 27/100 | $8M | 13 mo ago | 16 16 → 17 (+6%) · sector median +45% | Virginia Klausmeier President & CEO | WordPressMySQLPHP+22 | — | 23 patents Lithium‑ion battery cathode material synthesis and nanostructured carbon‑coated composites | 1 partnership |
| 39 | Endomimetics Developer of bio-nanometrics coating technology 14Funding top 38%Moat top 45%Product top 46%Talent bottom 49% All 9 signals ▾Fundingtop 38% Moattop 45% Producttop 46% Talentbottom 49% Innovationbottom 42% Patentsbottom 37% Techbottom 31% Globalbottom 31% Marketbottom 21% Funding: Raised $8.4M across 8 rounds · 8 rounds over 4 yrs (2.0/yr) Moat: Editorial + unicorn rating 4/10 · IP moat: 2 patents rank vs industry peers · Fliar Intelligence Index 14/100 | $8M | 10 mo ago | 7 | Joseph Garner Chief Executive Officer | — | — | 2 patents Peptide amphiphile therapeutics and biomaterial drug delivery systems | — |
| 40 | Robigo Manufacturer and supplier of crop-protection biologicals | $8M | 9 mo ago | 9 | Jai Padmakumar Co-Founder | Cart FunctionalitySquarespace CommerceSquarespace+17 | — | 7 patents Plant microbial vectors for RNAi delivery in crop protection and biotechnology | — |
| 41 | Albert Invent Developer of an end-to-end R&D platform for chemistry and materials | $8M | 15 mo ago | 66 | Ken Kisner Strategy | WebflowSentryZendesk+26 | — | — | 3 partnerships · 1 award |
| 42 | Chemfinitytech Developer of separations technologies for critical mineral recovery and resource circularity 62Talent top 28%Funding top 32%Global bottom 48% All 3 signals ▾Talenttop 28% Fundingtop 32% Globalbottom 48% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $7.4M across 3 rounds · 3 rounds over 1 yrs (3.0/yr) rank vs industry peers · Fliar Intelligence Index 62/100 | $7M | 10 mo ago | — | Jeffrey Long Co-Founder | — | — | — | 1 award |
| 43 | Jord BioScience Developer of microbial inoculants for plant growth and protection | $7M | 17 mo ago | 11 | — | WordPressMySQLPHP+16 | — | — | — |
| 44 | Copernic Catalysts Provider of sustainable catalysts | $7M | 19 mo ago | 3 | Aruna Ramkrishnan CTO and Co-founder | — | — | — | 1 award |
| 45 | PhylloTech Biotechnology company providing protein products for research use, including cytokines and other products | $6M | 12 mo ago | 2 | Colin Shepherd Co-Founder & COO | — | — | — | — |
| 46 | OCO Manufacturer of green formic acid 8Moat top 48%Funding top 50%Tech bottom 42%Global bottom 36% All 6 signals ▾Moattop 48% Fundingtop 50% Techbottom 42% Globalbottom 36% Newsbottom 21% Marketbottom 19% Moat: Editorial + unicorn rating 4/10 · 9 curated direct competitors tracked Funding: Raised $5.8M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 8/100 | $6M | 5 mo ago | 4 | — | WordPressMySQLPHP+17 | — | — | 2 awards |
| 47 | Sironix Developer of plant-based ingredients for cleaning and personal care products | $6M | 20 mo ago | 9 | Paul Dauenhauer Co-Founder | — | — | — | 1 launch |
| 48 | Ascribe Bioscience Developer of natural crop protection products using soil microbiome molecules | $6M | 8 mo ago | 8 | — | — | — | 36 patents Ascaroside-based agrochemical formulations for herbicide synergy and phytotoxicity mitigation | 1 launch · 1 partnership |
| 49 | Living Ink Biomaterial company manufacturing algae based color pigments | $2M | 15 mo ago | 11 | — | Cart FunctionalitySquarespace CommerceSquarespace+13 | — | — | 1 partnership · 1 award |
| 50 | AEMS Provider of viscosity solutions for pharmaceutical and industrial formulations | $350K | 3 mo ago | 4 | Nicholas Colella Co-Founder | — | — | 2 patents Agricultural chemical formulations for plant protection and sanitation applications. | — |
Top 12 Chemicals Tech companies in United States
#1
Public · Skokie, Illinois · founded 2005 · 367 employees$869.3Mraised▾
Developer of technology converting carbon-rich gases into fuels and chemicals. The company provides solutions for energy security and economic strength. It transforms industrial emissions and gasified waste into ethanol. This ethanol serves as a building block for sustainable aviation fuel and chemical derivatives. The company partners with industries to capture and process carbon-rich gases.
- Jan 2026Post IPO$20M
- Jun 2025Grant (prize money)$2.5M
- Apr 2025Grant (prize money)$1.9M
- Jan 2025Grant (prize money)$2.5M
#2
Series D · Woodbridge, Connecticut · founded 2011 · 19 employees$39.2Mraised▾
Manufacturer of diversified green chemicals. It develops bio-renewable speciality chemicals. Its product portfolio includes chemicals for cosmetic and personal care, flavour and fragrance, renewable polymers and bioactive. It produces petroleum-like biopolymers from sustainable resources.
- Feb 2023Series D—
- Jun 2020Conventional Debt$3M
- Jan 2020Series C$12M
- Nov 2019Series B$15.6M
#3
Series B · Solon, Ohio · founded 2014 · 163 employees$250Mraised▾
Bio-based solutions enhancing performance across agriculture, industrial, mining, and oil & gas. They specialize in high-performance intermediary formulations using glycolipids and microbes to surpass conventional chemistry. Their solutions enhance soil quality, nutrient uptake, crop production, recovery, stimulation, flow assurance, metal extraction, mineral extraction, and product performance while reducing chemical usage. They offer formulated ingredients designed for various industries, providing bio-enhanced solutions that are easy to adopt and cost-effective. They focus on sustainability, delivering eco-friendly benefits without compromising efficacy. Their proprietary platform merges biology, technology, and manufacturing to deliver high-efficiency ingredients via intermediates that outperform conventional chemicals. They provide hands-on technical expertise and support, offering custom, high-performance bio-based solutions to solve formulation challenges.
- Dec 2025Series B$20M
- Apr 2023Conventional Debt$117M
#4
Series A · Houston, Texas · founded 2019$43.7Mraised▾
Provider of roof coating, fireproofing, insulation, and custom formulation
- Apr 2026Series A$29.4M
- Jul 2023Series A$9.3M
- Dec 2020Seed$5M
#5
Series B · Knoxville, Tennessee · founded 2021 · 3 employees$21.9Mraised▾
Manufacturer of green acrylonitrile and acetonitrile from biorenewable feedstocks. It provides alternatives to oil and gas derived propylene. The company focuses on manufacturing drop-in molecules. It aims to provide a green alternative that reduces carbon emissions and improves safety.
- May 2026Series B$13M
- Jun 2024Series A$9.8M
- Aug 2022Series A$10.6M
- Feb 2021Seed$1.5M
#6
Series B · New York City, New York · founded 2022 · 28 employees$65Mraised▾
AI-based fragrance digitization system. It leverages artificial intelligence to digitize scents, enabling computers to recognize and generate aromas for various applications, including perfumes, threat detection, and disease prevention.
- Feb 2026Series B$70M
- Nov 2023Series A$5M
- Nov 2023Grant (prize money)$3.5M
- Jan 2023Series A$60M
#7
Series C · Santa Monica, California · founded 2013 · 83 employees$185.4Mraised▾
Developer of agricultural solutions designed to protect crops from insect damage. The company focuses on creating environmentally sustainable products for farmers. It offers alternatives to traditional pesticides, utilizing scientific research and development. The company is committed to supporting sustainable agriculture practices.
- Sep 2025Conventional Debt—
- Sep 2025Series C$25.5M
- Feb 2021Series C$10M
- Dec 2020Series C$45.5M
#8
Series C · Boulder, Colorado · founded 2014 · 24 employees$47.8Mraised▾
Manufacturer of bio-based specialty chemicals. Its technology platform enables the production of sustainable and cost-effective chemicals. Its chemicals serve as ingredients in dietary supplements, nutraceuticals, cosmetic actives, and bio-based materials. It focuses on developing and commercializing a range of bio-based chemical products. It offers a standardized and scalable technology platform for product development and commercialization.
- Dec 2025Series C$1.4M
- Oct 2025Series C$904.5K
- Apr 2025Series C$4.8M
- Aug 2022Series B$66.7K
#9
Series A · Natick, Massachusetts · founded 2018 · 12 employees$71.2Mraised▾
Manufacturer of microbial crop nutrition products. It offers a biological solution that improves the activity of naturally occurring soil microbes to develop fertilizing abilities. Its product claims to facilitate the activity of soil nitrogen-fixing bacteria and enables them to store the energy derived from renewable electricity and carbon dioxide.
- Nov 2025Series A$15.5M
- Jan 2022Series A$50M
- Mar 2021Seed$10M
- Aug 2020Seed$5.7M
#10
Funding Raised · Pembroke, Virginia · founded 1998 · 25 employees$30.5Mraised▾
Nanomaterial innovator specializing in sensors, additive manufacturing, and polymer design. The company excels in nanomaterial and complex polymer syntheses, offering scale-up volumes for collaborative projects. Capabilities include quantum electronics and sensors, enhanced with artificial intelligence for extreme environments, and additive manufacturing, specializing in 3D printing of hybrid materials. Polymer design leverages extensive experience in macromolecular innovation. Technologies encompass consulting with materials laboratories and sensor development for physical, AI-enhanced, and wireless chem/bio sensors. Prototyping services are available with multiple 3D printers. Metal rubber composites combine conductivity and elasticity for electrodes and sensors. The company is committed to outreach and education through internships, mentorship programs, lab tours, and scholarships, fostering a cleaner environment through sustainable practices. The website offers login, cart, search, contact form, privacy policy, and terms of service.
- Dec 2025Grant (prize money)$1.4M
- May 2025Grant (prize money)$2.5M
- Mar 2025Grant (prize money)$123.9K
- Mar 2025Grant (prize money)$200K
#11
Series D · Boulder, Colorado · founded 2013 · 65 employees$162.1Mraised▾
Manufacturer of atomic layer deposition equipment and related coated materials. The company provides semi ALD systems for semiconductor wafer fabrication, applying ultra-thin coatings. It offers powder ALD equipment for coating granular materials, enhancing conductivity and stability. The company's products support advancements in energy storage, semiconductors, defense, and aerospace applications.
- Apr 2025Series D$40M
- Oct 2024Series C$10M
- May 2023Series C$50M
- Dec 2022Series B$44.2M
#12
Series F · Kalamazoo, Michigan · founded 2001 · 54 employees$203.7Mraised▾
Revolutionizing crop protection with peptide technology for sustainable agriculture. The company is focused on developing novel insecticides using peptide technology derived from natural sources like spider venom. These products offer new modes of action for pest control, effectively targeting pests on high-value crops while ensuring environmental safety. The insecticides are designed to manage resistance, protect crop yield and quality, and promote sustainability across the agriculture and food industries. The company's approach emphasizes biotechnology to enhance the sustainability value of agricultural land, reduce reliance on synthetic chemical pesticides, and support beneficial insect populations. The company is committed to bringing safe, novel modes of action to the market quickly, providing growers with effective and environmentally friendly solutions for crop protection.
- Jan 2025Conventional Debt—
- Jan 2025Series F$82.9M
- Aug 2022Series E$10M
- May 2022Series E$82M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Chemicals Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Advanced Materials is moving in the United States
A read on the academic research around Advanced Materials — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,306 United States-affiliated papers.
- Georgia Institute of Technology46
- Purdue University West Lafayette46
- North Carolina State University39
- Northeastern University36
- Texas A&M University34
- Smart material61→108
- Soft robotics4→36
- Morphing8→35
- Nanotechnology19→46
- Elastomer18→41
- Nanotechnology12→29
- Soft robotics2→13
- Fabrication4→12
- Liquid crystal3→10
- 3D printing6→12
- Smart material10→18
- Nanotechnology7→9
- Shape-memory alloy2→4
Where advanced materials is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing advanced materials patents in the United States
United States advanced materials patent filing is cooling — 88,582 filings from 8,000 assignees (2016–2025), led by IBM, General Electric, Halliburton Energy Services; annual filings 9852→6833.
- IBM5882
- General Electric4499
- Halliburton Energy Services3870
- Intel3637
- UNIV California3345
- 3M Innovative Properties3297
- Corning3138
- United States Gypsum2668