Best Clinical Data Repository Companies in United States
The 406 best Clinical Data Repository companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Imaging Advantage.
Clinical Data Repository companies in the United States number more than 400 tracked names, and this page ranks the best among them by disclosed equity funding and recent funding momentum. Total disclosed capital across all 406 companies sits at $300M, and one name accounts for nearly all of it: Imaging Advantage at $295M, which means everyone else is splitting the remaining $5M. That's a concentration story worth noticing.
The broader market gives context. Global Clinical Data Repository revenue was pegged at roughly $1.2B in 2018 and is forecast to reach $2.7B by 2030, a 12.9% CAGR driven by the increasing complexity of clinical trials and the persistent need for data standardization. So the demand curve is real, even if U.S. venture dollars haven't spread evenly across the field yet. I'd keep an eye on the mid-tier names like ReDoc Software ($3M) and ocs homecare ($2M), because that's where early momentum tends to compound fastest. No unicorns here yet. Does that surprise you, given the market size? It shouldn't, entirely. Alchemist Accelerator stands out as the most active investor in this cohort, which tells you the sector is still at a stage where accelerator bets make sense alongside larger strategic plays from Oracle and Medidata.
- benzinga.com
Ranked: Best Clinical Data Repository companies in United States
| # | Company | Disclosed funding | Employees | Founded | Stage | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | abeo Abeo provides services for anesthesiology such as billing, transcription, coding, business, and managed care… | — | 550 | 2007 | Acquired | ZohoMicrosoft ASP.NETNginx+2 | Top 50M | 15 patents Patents concentrated in transport & manufacturing processes | — |
| 2 | Active Health Management ACTIVE Health Management, Inc. | — | 500 | 1998 | Acquired | — | — | — | — |
| 3 | caradigm Caradigm provides intelligent healthcare analytics and population health management solutions. | — | 400 | 2012 | Acquired | — | — | — | — |
| 4 | American Healthcare Holdings Provider of healthcare technology services. The company develops software which connects patients, providers… | — | 350 | 1997 | Acquired | — | — | — | — |
| 5 | Imaging Advantage Provider of an innovative and scalable cloud-based radiology technology intended to optimize provider… 53Funding top 30%Market top 41%Moat top 45%Patents bottom 49% All 6 signals ▾Fundingtop 30% Markettop 41% Moattop 45% Patentsbottom 49% Globalbottom 39% Innovationbottom 35% Funding: Raised $295M · 5 rounds over 14 yrs (0.4/yr) Market: 201 employees (top 27% of SaaS) rank vs industry peers · Fliar Intelligence Index 53/100 | $295M | 201 | 2006 | Acqui-Hired | — | — | 21 patents Medical imaging data distribution, workflow integration, and reporting systems | — |
| 6 | Antek Healthware Developer of healthcare analysis and automation software. | — | 201 | 1987 | Acquired | — | — | — | — |
| 7 | BACTES Imaging Solutions Provider of medical record services. The company provides electronic exchange, delivery and integration of… | — | 201 | 1991 | Acquired | — | — | — | — |
| 8 | Bond Technologies Developer of clinical software. The company offers services such as billing, systems support, practice… | — | 201 | 2003 | Acquired | — | — | — | — |
Top 6 Clinical Data Repository companies in United States
#1
Acqui-Hired · United States · founded 2006 · 201 employees$295Mraised▾
Provider of an innovative and scalable cloud-based radiology technology intended to optimize provider utilization and efficiency. The company's cloud based radiology technology integrates disparate information technology (IT) systems, utilizing business and clinical algorithms enabling health care companies to match supply and demand across networks and optimize healthcare utilization.
#2
Acqui-Hired · United States · founded 1995 · 55 employees$2.8Mraised▾
Provider of clinical documentation software designed for Physical, Occupational and Speech Therapists. The company's product is designed to address the clinical documentation and business needs of physical therapists, occupational therapists and speech-language pathologists.
#3
Acqui-Hired · Seattle, Washington · founded 1997 · 51 employees$1.7Mraised▾
Provider of software services to healthcare sector. The company offers analytics software services that offer clinical outcomes improvement, hospitalization insights and quality assurance bench-marking and reporting.
#4
Public · Eden Prairie, Minnesota · founded 2009 · 22 employees—raised▾
Developer of a medical imaging data platform designed to provide prompt and secure access to curated medical images. The company's technology helps to electronically share and exchange imaging studies between hospitals, clinics, physicians, and researchers, eliminating traditional information silos to improve care quality, enabling clients to manage their medical image exchange, and reducing healthcare costs and waste.
#5
Seed · St. Louis, Missouri · founded 2016—raised▾
Developer of a healthcare software designed to facilitate communication between care providers. The company's software facilitates secured and encrypted in-hospital, real-time communication for sensitive PHI and integrates seamlessly with the hospital's electronic medical records, enabling medical practitioners to significantly reduce the turnover time that would translate to more cases completed per day and make substantial cost-savings due to minimizing turnover inefficiency.
#6
Deadpooled · Johnstown, PA · founded 1994 · 110 employees—raised▾
MedcomSoft Record is a fully interoperable EMR that meets Stage 1 objectives for Meaningful Use, physicians can qualify for payment incentives for implementation starting in the last quarter of 2010 and beyond.
Funding & investor landscape
Market landscape — 10 sub-themes by coverage
Share of Clinical Data Repository coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Bioinformatics is moving in the United States
A read on the academic research around Bioinformatics — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 13,110 United States-affiliated papers.
- Harvard University633
- Broad Institute433
- Howard Hughes Medical Institute318
- Stanford University287
- Johns Hopkins University287
- Gene83→532
- Transcriptome25→436
- Genome117→419
- Disease6→218
- Immune system11→219
- Disease17→407
- Immune system4→266
- Gene38→281
- Transcriptome13→238
- Biomarker2→208
- Disease27→311
- Immune system6→152
- Cancer17→130
- Clinical trial4→111
- Biomarker2→92
Where bioinformatics is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing bioinformatics patents in the United States
United States bioinformatics patent filing is accelerating — 246 filings from 64 assignees (2016–2025), led by Edico Genome, Illumina, UNIV Washington; annual filings 22→23.
- Edico Genome129
- Illumina60
- UNIV Washington18
- Nantomics9
- Genomsys7
- Baluch Mohamed Khoso7
- Microsoft6
- Contamination Source Identificat5
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.