Best Deep Tech Companies in California, United States
The 172 best Deep Tech companies in California, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: neato robotics.
Ranked: Best Deep Tech companies in California
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | neato robotics Neato Robotics is a venture-funded startup developing robotic-based household appliances. | $49M | 154 mo ago | Acquired | — | 2005 | RubyRuby on RailsEnvoy+10 | 78 patents Autonomous floor‑cleaning robots with sensor‑based dirt detection and navigation mapping | — |
| 2 | nugen technologies NuGEN Technology is a provider of genomics sample preparation solutions enabling scientists to access true… | $39M | 140 mo ago | Acquired | — | 2000 | — | 185 patents Integrated nuclear energy conversion systems delivering electricity, heat, and mechanical power | — |
| 3 | mindshow Mindshow is an app for creating, sharing, and experiencing shows in VR. | $25M | 62 mo ago | Series A | — | 2014 | — | 43 patents Real-time VR scene creation and animation using motion‑capture and video rendering | — |
| 4 | cookbook Cookbook specializes in simplifying the cost for companies in building developers web3. | $2M | 37 mo ago | Seed | — | 2022 | SentryNode.jsRadix UI+16 | — | — |
| 5 | RNAV8 Bio Developer of RNAs to treat various diseases | $600K | 41 mo ago | Seed | Devan Shah Founder & CEO | 2022 | — | — | — |
| 6 | madesolid MadeSolid develops a production material designed to develop advanced materials for 3D printers. | $303K | 136 mo ago | Deadpooled | — | 2013 | — | 6 patents Additive manufacturing material selection, color control, and rheology optimization | — |
| 7 | Basilica API that embeds high-dimensional data like images and text | $150K | 80 mo ago | Seed | Michael Lucy Co-Founder | 2018 | Node.jsTailwind CSSPlyr+12 | — | — |
| 8 | floydhub FloydHub is a deep learning platform for training and deploying your machine learning and AI models in the… | $120K | 104 mo ago | Deadpooled | — | 2016 | — | — | — |
| 9 | pembient Pembient is a company that creates synthetic animal products to help stop poaching. | $100K | 137 mo ago | Seed | — | 2015 | Squarespace CommerceSquarespaceMathJax+11 | 7 patents Synthetic rhino horn for pharmaceutical and traditional medicine applications | — |
Top 12 Deep Tech companies in California
#1
Seed · San Francisco, California · founded 2022 · 6 employees$2Mraised▾
Developer of a free smart contract marketplace intended to find, customize and deploy any smart contract. The company's marketplace provides developers with tools to sift through a range of open-source smart contract templates and access documentation about how to operate those contracts, enabling users to get documentation, audits, and source code publicly.
#2
Seed · Laguna Niguel, California · founded 2022$599.5Kraised▾
Developer of RNAs to treat various diseases
#3
Series A · Los Angeles, California · founded 2014 · 57 employees$25Mraised▾
Operator of a three-dimensional animation studio intended to make story creation simple and fun. The company's studio helps users to make animated movies in virtual reality, bring characters to life with voice and body movements and record actions from different angles, enabling clients to build stories in virtual reality.
#4
Acquired · Newark, California · founded 2005 · 131 employees$48.6Mraised▾
Manufacturer of robotic vacuum cleaners designed to make house cleaning easy. The company's robotic vacuum cleaners are Wi-Fi enabled with intelligent navigation to start, stop, pause, schedule and receive notifications anywhere in the house, thereby helping consumers to clean rooms anytime, from anywhere with the application.
#5
Acquired · San Carlos, California · founded 2000 · 70 employees$39.2Mraised▾
Provider of genomics sample preparation services intended to help the analysis and discovery of biological mechanisms, cellular responses and disease pathologies. The company's genomics sample preparation services ensures robust and reproducible results for researchers seeking to predict disease risk and drug response, potentially shortening the path to treatment, enabling scientists to access true biology in all samples, independent of type, quality and amount for analysis on leading analytical platforms.
#6
Seed · San Francisco, California · founded 2018$150Kraised▾
Provider of network effect services intended to embed high-dimensional data like images and text. The company's service uses a technique called embedding to transform high-dimensional data into usable features by training deep neural networks to perform a mix of tasks on private and public data, enabling clients to get the benefits of transfer learning without the expensive data gathering and pretraining steps.
#7
Deadpooled · Emeryville, California · founded 2013 · 20 employees$303.3Kraised▾
Developer of production material designed to develop advanced materials for 3D printers. The company's production material turns filaments and ultra-violet curable resins with superior mechanical properties, enabling clients to avail enhanced 3D printers.
#8
Deadpooled · San Francisco, California · founded 2016 · 4 employees$120Kraised▾
Developer of a deep learning platform intended to facilitate training in the cloud across teams and vertical management strata. The company's platform helps to configure CPU and GPU environments primed for deep learning, saves projects, databases automatically through cloud-based interactions and have an in-built web dashboard to track, monitor, edit and share project progress, job-related queries, enabling clients to share and collaborate on their deep learning projects across single and multiple teams and increase team productivity through performance reviews and project planning.
#9
Seed · San Francisco, California · founded 2015 · 2 employees$100Kraised▾
Operator of a biotechnology company intended to produce bio-fabricated horn using DNA and 3D printed keratin. The company fabricates wildlife products including rhino horn, elephant ivory and other products to replace the illegal wildlife trade, enabling wildlife organizations to stop poaching activities.
#10
Seed · Mountain View, California · founded 2019 · 6 employees—raised▾
Manufacturer of lightweight batteries designed to provide a range of sustainable energy. The company's battery materials are made of thin copper and nanofiber which is an abundant, renewable, and sustainable biopolymer, enabling customers to purchase batteries that are lightweight, cheaper, and have stronger alternatives.
#11
Seed · San Francisco, California · founded 2014 · 7 employees—raised▾
Developer of an AI(artificials intelligence)-driven platform designed for interactive entertainment. The company's offers people to come together through immersive online experiences, allows users to engage in immersive 3D (3 dimensional) story worlds, real-time interactive platform, enabling the users to influence the story and chat with virtual characters in real-time, while creators can build experiences to monetize on their marketplace.
#12
Seed · San Francisco, California · founded 2012 · 3 employees—raised▾
Developer of an augmented reality application designed to build stories in holograms. The company's application provides an online tool that creates narrated multimedia stories by combining text, video, audio, maps, links and timelines, enabling users to create interactive and entertaining stories in virtual and augmented reality.
Funding & investor landscape
Market landscape — 10 sub-themes by coverage
Share of Deep Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.