Best ENT Disorders Companies in United States
The 174 best ENT Disorders companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Earlens Corporation.
The 174 ENT Disorders companies tracked in the United States have pulled in $2.5B in disclosed funding, and this directory ranks them by equity raised and recent funding momentum. No unicorns here. But the spread across those 174 companies tells a sharper story than any single headline number.
Earlens Corporation leads the field at $326M raised, which is more than twelve times the next significant filer. NeuroMark Genomics sits at $110M, OtoNexus at $33M, and IotaMotion at $25M. I find that gap between Earlens and the rest genuinely striking. The underlying market is valued at roughly $2.1B globally with a 2.0% CAGR, a measured pace that reflects the sector's dependence on incremental therapeutic gains rather than blockbuster cycles. Demand is being pushed by air pollutants, chemical exposure, and the adverse effects of existing treatments. So you're looking at a market where clinical precision matters more than growth velocity. As shown in 2015 research on pediatric ENT prevalence, the patient burden is substantial and consistent, which keeps institutional backers like New Enterprise Associates and HHS writing checks into this space year after year.
- biospace.com
Ranked: Best ENT Disorders companies in United States
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Earlens Corporation Provider of hearing aids for people with less hearing power 62Funding top 17%Moat top 19%Tech top 27%Patents top 31% All 10 signals ▾Fundingtop 17% Moattop 19% Techtop 27% Patentstop 31% Innovationtop 36% Talenttop 38% Markettop 49% Globalbottom 47% Growthbottom 39% Newsbottom 21% Funding: Raised $326M across 15 rounds · 15 rounds over 16 yrs (0.9/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 362 patents rank vs industry peers · Fliar Intelligence Index 62/100 | $326M | 15 mo ago | 129 129 → 111 (-14%) | 2005 | Rodney Perkins Founder | WordPressSentryApple iCloud Mail+49 | 362 patents Advanced contact hearing aids and acoustic signal processing for ear canal devices | — |
| 2 | Decibel Therapeutics Developer of new medicines to protect, repair and restore hearing capacity | $170M | 67 mo ago | 62 | 2015 | — | — | 234 patents Patents concentrated in chemistry & materials | — |
| 3 | Akouos Developer of gene therapies to restore and preserve hearing capabilities in genetically defined populations | $163M | 75 mo ago | 92 | 2016 | Manny Simons Founder & CEO | — | 279 patents Gene‑therapy and inner‑ear drug delivery for non‑age‑related sensorineural hearing loss. | — |
| 4 | Otonomy Developer of treatments for diseases of the inner and middle ear | $144M | 145 mo ago | 51 | 2008 | Jay Lichter Co-Founder | — | 311 patents Otic drug delivery formulations, especially growth factor and TRK agonist therapies for ear conditions | — |
| 5 | Frequency Therapeutics Developing regenerative therapeutic for reversing hearing loss | $136M | 70 mo ago | 48 | 2015 | Will McLean Co-Founder | — | — | — |
| 6 | Advanced Bionics Provider of advanced cochlear implants and hearing technology for powerful connections | $128M | 221 mo ago | 687 687 → 1,125 (+64%) | 1993 | — | Adobe Experience ManagerJavaSalesforce+24 | 873 patents Patents concentrated in health & consumer products | — |
| 7 | NeuroMark Genomics Developer of a system for chronic rhinitis treatment via radiofrequency. | $110M | 4 mo ago | — | 2018 | David Townley Co-Founder & CTO | WordPressMySQLPHP+25 | — | — |
| 8 | Zounds Hearing Online slot site offering deposit options with potential jackpot wins | $103M | 144 mo ago | 43 | 2005 | — | Microsoft ASP.NETAmazon ALBAmazon Web Services+10 | 13 patents Advanced hearing aid tip designs, calibration methods, and communication/control technologies. | — |
| 9 | IntriCon Developer of hearing aid | $95M | 93 mo ago | 1,000 | 1977 | Mark Gorder Founder & Director | WordPress Block EditorWordPressApple iCloud Mail+27 | 51 patents Personalized hearing aid fitting algorithms and advanced microphone sensor technologies | 1 partnership |
| 10 | Entellus Medical Developer of suite of products for treating chronic sinusitis | $91M | 107 mo ago | 286 | 2006 | — | — | 253 patents Minimally invasive sinus therapy devices and adjustable endoscopic imaging accessories | — |
| 11 | Perceive Bio Developer of therapeutics to treat diabetes and eye diseases | $78M | 41 mo ago | 12 | 2021 | Anne Rubin President | — | — | — |
| 12 | Intersect ENT Developer of drug releasing implant to treat sinusitis | $77M | 73 mo ago | 371 | 2003 | — | — | — | — |
| 13 | Spirox Provider of non-invasive treatment of nasal valve obstruction | $70M | 123 mo ago | 50 | 2013 | — | — | 119 patents Nasal implant devices and minimally invasive delivery systems for therapeutic and diagnostic use | — |
| 14 | Acclarent Developer of a balloon-based sinuplasty technology | $61M | 209 mo ago | 349 349 → 182 (-48%) | 2004 | — | — | 1,797 patents Patents concentrated in health & consumer products | 4 launchs |
| 15 | Sonitus Medical Online pharmacy providing affordable generic and brand medications globally | $58M | 145 mo ago | 45 | 2006 | — | — | 292 patents Intra‑oral acoustic communication and hearing‑aid devices with vibration/audio processing | — |
| 16 | Lantos Provider of 3D digital ear canal scanners | $54M | 54 mo ago | 26 | 2009 | — | — | 12 patents Medical cavity scanning and fluorescent imaging with fluid handling and fiducial markers | — |
| 17 | Lyra Therapeutics Biotechnology firm innovating localized therapies for chronic rhinosinusitis (CRS) | $53M | 36 mo ago | 75 | 2005 | George Whitesides Co-Founder | DrupalPHPZURB Foundation+20 | — | — |
| 18 | Whisper Advanced speech recognition and transcription model powered by artificial intelligence | $53M | 68 mo ago | 54 | 2017 | Andrew Song Co-Founder & COO | — | 17 patents Patents concentrated in electrical & electronics | — |
| 19 | Tusker Medical Online gaming platform offering diverse slot games with high RTP | $48M | 83 mo ago | 26 | 2016 | — | — | 159 patents Otic drug delivery via iontophoresis and intraoperative medical visualization systems | — |
| 20 | Skylark Bio Developer of therapeutics for ear disorders | $41M | 46 mo ago | — | 2021 | Casey Maguire Co-Founder | — | — | 1 job opening · 1 partnership |
| 21 | Otolith Labs Provider of a wearable platform for treating vertigo and motion sickness | $34M | 22 mo ago | 16 | 2015 | Samuel Owen Founder & CEO | WordPressMySQLPHP+17 | — | — |
| 22 | OtoNexus Developer of ultrasound device to non-invasively detect middle ear infections | $33M | 9 mo ago | 16 | 2010 | Caitlin Cameron Co-Founder & CEO | — | — | — |
| 23 | IotaMotion Provider of robotic system for cochlear implantation surgery | $25M | 3 mo ago | 12 | 2015 | Marlan Hansen Co-Founder & Chief Medical Officer | WordPressMySQLPHP+14 | 50 patents Robotic and modular systems for precise surgical implant delivery and cochlear electrode insertion | 1 launch |
| 24 | ENTrigue Surgical Developer of devices for sinus surgery | $24M | 174 mo ago | 19 | 2007 | Fred Dinger ex-CEO | — | 85 patents Patents concentrated in health & consumer products | — |
| 25 | Sound Pharma Specialty company developing novel treatment for hearing loss | $23M | 96 mo ago | 1 | 2002 | Jonathan Kil CEO & CMO | WordPressMySQLPHP+21 | — | — |
| 26 | Spiral Therapeutics Developer of therapeutics to treat balance disorders and hearing loss | $20M | 8 mo ago | 8 | 2016 | Hugo Peris Chief Executive Officer | WordPressMySQLPHP+18 | — | — |
| 27 | Esteem Hearing Developer of implanted hearing devices | $19M | 193 mo ago | 22 | 1995 | — | — | — | 1 launch |
| 28 | Preceptis Medical Surgical tool for ear tube procedures | $19M | 2 mo ago | 4 | 2011 | — | — | — | — |
| 29 | Navage Nasal care products for congestion relief and improved breathing | $19M | 80 mo ago | 24 | 2007 | Martin Hoke Founder | Amazon WebstoreCart FunctionalityShopify+42 | — | — |
| 30 | SONITUS Technologies Sensory interface platform enabling voice connectivity in extreme conditions | $17M | 101 mo ago | 8 | 2009 | — | WordPressMySQLPHP+27 | — | — |
| 31 | PhotoniCare Developer of optical imaging device for viewing eardrums | $16M | 19 mo ago | 26 | 2013 | Ryan Shelton COO & Co-founder | WordPressMySQLPHP+24 | 39 patents AI-powered otoscopic imaging and sensor‑fusion devices for ear disease diagnosis | — |
| 32 | Lively Developer of hearing aids and an online audiologist platform | $16M | 87 mo ago | 125 | 2018 | Nicole Cadoret Co-Founder | — | — | — |
| 33 | Chemo Mouthpiece Developer of a cryotherapy device to cool the entire oral cavity | $15M | 19 mo ago | 5 | 2017 | David Yoskowitz Founder & CEO | WordPressMySQLPHP+22 | — | 1 partnership |
| 34 | Hummingbird Provider of medical devices for ENT surgeons to perform ear tube procedures in child | $14M | 40 mo ago | 9 | 2011 | — | WordPressMySQLPHP+24 | 13 patents Patents concentrated in health & consumer products | — |
| 35 | iHear Medical Brandable domain name ideal for medical startups and entrepreneurs | $13M | 104 mo ago | 20 | 2010 | — | — | — | — |
| 36 | Eversound Provider of wireless headphone system designed for senior citizens with hearing loss | $13M | 67 mo ago | 32 | 2015 | — | — | — | — |
| 37 | OtoSet Developer of ear wax removal device for providers | $13M | 41 mo ago | 12 | 2016 | Aadil Diwan Co-Founder & CTO | Cart FunctionalityShopifyYouTube+27 | — | — |
| 38 | Diceros Therapeutics Developer of therapeutics for the treatment of chronic rhinosinusitis | $13M | 45 mo ago | — | 2022 | Stephen Seiler Founder & CEO | — | — | — |
| 39 | Diceros Therapeutics Developer of therapeutics for the treatment of chronic rhino sinusitis | $13M | 45 mo ago | — | 2022 | Stephen R Seiler CEO | — | — | — |
| 40 | MyPurMist Natural steam inhalers and air purifiers for respiratory relief | $9M | 122 mo ago | 5 | 2001 | Lars Barfod Chief Executive Officer | Cart FunctionalityShopifySentry+43 | — | — |
| 41 | Audicus Online platform offering hearing Aids | $9M | 21 mo ago | 58 | 2011 | Patrick Freuler Founder & CEO | Cart FunctionalityBigCommerceUnbounce+29 | 2 patents Audiology hearing test devices and diagnostic hearing assessment systems | 1 job opening |
| 42 | Tivic Health Developer of a bioelectronic medical device for the treatment of sinusitis | $8M | 6 mo ago | 16 16 → 13 (-19%) | 2016 | Jennifer Ernst CEO & Co-founder | Cart FunctionalityShopifySentry+30 | — | — |
| 43 | RestorEar Developer of cold therapy device for hearing loss prevention | $8M | 13 mo ago | — | 2017 | Curtis King Co-Founder & CEO | — | 4 patents Medical devices for localized ear hypothermia therapy, including therapeutic headbands. | 3 launchs |
| 44 | EnvantageDX In-vitro diagnostics for rapid ear, nose, and throat illness detection | $7M | 64 mo ago | 6 | 2013 | Joseph Skraba President & CEO | — | — | — |
| 45 | Ting Therapeutics Developer of novel therapeutics to prevent and treat hearing loss | $6M | 14 mo ago | — | 2018 | Tal Teitz Co-Founder | — | — | — |
| 46 | WiscMed Developer of an otoscope for an ear infection | $6M | 10 mo ago | — | 2015 | James Berbee Co-Founder & Chairman & CEO | Cart FunctionalityShopifyVimeo+28 | — | — |
| 47 | Jacaranda Biosciences Biotechnology company focused on developing novel treatments for hearing loss | $2M | 13 mo ago | — | 2014 | Steven Sherr Co-Founder & CEO | — | — | — |
| 48 | Eosera Doctor-recommended ear care solutions for earwax, pain, and itch relief | $1M | 30 mo ago | 16 | 2015 | — | ShopifyReactstyled-components+32 | 5 patents Earwax removal pharmaceutical compositions and delivery methods | — |
| 49 | Tympanogen Provider of gel patch for chronic tympanic membrane perforations | $1M | 14 mo ago | 8 | 2014 | Elaine Horn-Ranney Co-Founder & CEO | Webflowanime.jscore-js+15 | 5 patents Patents concentrated in chemistry & materials | — |
| 50 | Qualia Oto Provider of software facilitating automation and optimization of transportation management | $816K | 14 mo ago | 5 | 2018 | — | — | — | 2 awards |
Top 12 ENT Disorders companies in United States
#1
Series C · Boulder, Colorado · founded 2018$110.2Mraised▾
Developer of a system for chronic rhinitis treatment via radiofrequency. The system uses low-power energy to disrupt posterior nasal nerves. It is designed as a minimally invasive solution. The technology includes a flexible shaft and leaflets for precise treatment.
- Feb 2026Series C$74.3M
- Dec 2024Series B—
- Jan 2021Series B$25M
- Jul 2020Grant (prize money)—
#2
Series B · Minneapolis, Minnesota · founded 2011 · 4 employees$19.2Mraised▾
Preceptis Medical is a medical device manufacturer developing surgical tools that allow ear tube procedures to be performed with reduced pain and surgical time for the pediatric patient. Its product, The HUMMINGBIRD TTS Tympanostomy Tube System, gives physicians the option to perform the procedure using moderate or conscious sedation. The device is not commercially available. Participated with Mayo Clinic and Children’s Hospitals and Clinics of Minnesota clinical study.
- Apr 2026Series B$2.6M
- Dec 2020Series B$3.2M
- Mar 2020Series B$3.7M
- Jun 2018Series B$6M
#3
Series B · Coralville, Iowa · founded 2015 · 12 employees$25Mraised▾
Provider of a robotic system for cochlear implantation surgery. It offers implantable robotics and, electrode re-positioning, aiming to allow for enhanced natural hearing preservation and optimized hearing quality over time. It also provides an open platform and robotic-assisted system to control the speed and acceleration of electrode insertion during surgery.
- Feb 2026Series B$1.9M
- Apr 2025Grant (prize money)$306.1K
- Jan 2025Series B—
- Jul 2023Series A$12M
#4
Series E · Menlo Park, California · founded 2005 · 129 employees$326.3Mraised▾
Provider of hearing aids for people with less hearing power. It develops a light-driven hearing aid that uses light to transmit sound. The device uses light and a small lens placed on the user's eardrum that directly activates your natural hearing system.
- Feb 2025Series E$8M
- Apr 2024Series E$18.8M
- Jan 2021Series E$33.2M
- Apr 2020Series D$12.2M
#5
Series C · Seattle, Washington · founded 2010 · 16 employees$32.9Mraised▾
Developer of an ultrasound device to non-invasively detect middle ear infections or Otitis Media in both children and adults. The doctor points the device at the eardrum, the device then sends an ultrasound signal that detects if fluid is present behind the eardrum, and if so, what type. Currently, doctors often suggest waiting for 24-48 hours to see if the problem resolves before prescribing antibiotics. According to the founder, OtoNexus's handheld doppler ultrasound will eliminate the need to wait.
- Sep 2025Grant (prize money)$1.2M
- Oct 2022Series C$12.9M
- Dec 2021Series C$1.9M
- Apr 2021Series C—
#6
Series B · Brisbane, California · founded 2016 · 8 employees$20.2Mraised▾
Developer of therapeutics to treat balance disorders and hearing loss. The company is advancing a therapeutic pipeline with a focus on balance disorders and hearing loss. The company's lead program, SPT-2101, is a sustained-release steroid formulation for the treatment of Ménière’s disease.
- Sep 2025Series B$27.1M
- Aug 2023Series B—
- Feb 2023Series B$10.9M
- May 2019Series A$5.6M
#7
Public · Menlo Park, California · founded 2016 · 16 employees$8Mraised▾
Developer of a bioelectronic medical device for the treatment of sinusitis. The company has developed a device called ClearUP that uses microcurrents applied on the cheek, nose, and brow bone to relieve pain caused by chronic sinusitis, allergies, and sinus infections.
- Dec 2025Post IPO$28.3M
- Aug 2019Seed$8M
#8
Series A · Middleton, Wisconsin · founded 2015$5.5Mraised▾
Developer of an otoscope for an ear infection. It provides views of the eardrum helping to make exams accurate. It also features an integrated LCD touchscreen, specula, and built-in nano camera. It helps in the diagnosis of an ear infection as it captures a photo of the eardrums.
- Jul 2025Series A$3M
- Nov 2022Series A$2M
- May 2020Series A$3.5M
#9
Funding Raised · Bozeman, Montana · founded 2017$7.7Mraised▾
Developer of cold therapy device for hearing loss prevention. The company specializes in hearing health, particularly with products designed to protect and potentially restore hearing after noise exposure such as their ReBound and ReBoundLite devices, which use cold therapy to help mitigate noise-induced hearing damage.
- Apr 2025Grant (prize money)$1.9M
- Mar 2025Grant (prize money)$2.5M
- May 2024Grant (prize money)$970.5K
- Apr 2021Grant (prize money)$2.2M
#10
Series A · Washington, DC, District of Columbia · founded 2015 · 16 employees$33.8Mraised▾
Provider of a wearable platform for treating vertigo and motion sickness. The platform is meant for travelers and virtual reality users. The company leverages its proprietary technology for addressing the problem of the vestibular system and eye control balance which causes vertigo and motion sickness. Their non-invasive technology uses a patent-pending transducer which sends consistent and noninformative stimuli to the vestibular system to mitigate the sensation of vertigo and motion-related nausea.
- Jul 2024Series A$4.9M
- Sep 2022Series A$24.8M
- Jun 2021Seed$3.3M
- Oct 2018Seed$750K
#11
Series B · Champaign, Illinois · founded 2013 · 26 employees$16.3Mraised▾
PhotoniCare is developing a handheld imaging tool that helps physicians to see through the eardrum. Their offering, ClearView imager, leverages optical coherence tomography (an optical imaging technique). It can build 3D reconstructions of tissue structure by analyzing the reflections of infrared light from tissue.
- Nov 2024Series B$4.6M
- Dec 2023Series A$4M
- Apr 2023Series A$1.1M
- Apr 2023Conventional Debt—
#12
Funding Raised · San Diego, California · founded 2018$5.6Mraised▾
Developer of novel therapeutics to prevent and treat hearing loss. The company focuses on developing drugs to address hearing loss caused by chemotherapy and noise exposure. Its research and development efforts center on adapting existing drugs and discovering new ones for this purpose. The company aims to bring these treatments to clinical trials and ultimately make them available to patients. The approach involves a focus on drug repurposing and discovery within a specific therapeutic area.
- Apr 2025Grant (prize money)$1.5M
- Jul 2020Grant (prize money)$748.8K
- Apr 2020Grant (prize money)$1.7M
- Dec 2019Grant (prize money)$1.6M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of ENT Disorders coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising