Best Enterprise Applications Companies in Cleveland, United States
The 151 best Enterprise Applications companies in Cleveland, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Within3.
Ranked: Best Enterprise Applications companies in Cleveland
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Within3 Provider of an online collaboration solutions | $103M | 68 mo ago | 196 196 → 120 (-39%) | Lance Hill Founder & CEO | WordPressApple iCloud MailMySQL+24 | 13 patents Integrating and analyzing biomedical datasets with linked databases and image/social network analytics | — |
| 2 | Remesh AI-powered platform for fast, high-quality, and cost-effective research | $43M | 42 mo ago | 150 | — | WebflowSentryAmazon Web Services+27 | — | 1 award |
| 3 | OnShift SaaS based staff scheduling and shift management software for the healthcare industry | $34M | 47 mo ago | 191 191 → 102 (-47%) | — | HubSpot CMS HubSentrySalesforce+20 | — | — |
| 4 | Axentis SaaS based GRC software for enterprises | $24M | 203 mo ago | 50 | — | — | — | — |
| 5 | Bravo Wellness Wellness incentive programs provider | $22M | 142 mo ago | 217 | — | RubySalesforceRuby on Rails+9 | — | — |
| 6 | AmpliFund Cloud-based grant management software for government | $19M | 74 mo ago | 87 | Scott Smith CEO | WordPressMySQLPHP+32 | — | — |
| 7 | BuyerQuest Provider of procure-to-pay software | $15M | 108 mo ago | 28 | — | Cart FunctionalityApple iCloud MailMicrosoft 365+25 | 3 patents Automated catalog management for e‑procurement platforms | — |
| 8 | Complion Software solutions for clinical trial regulatory documentation. | $14M | 73 mo ago | 33 | — | — | — | — |
| 9 | EmployStream Cloud based employee onboarding solution | $14M | 76 mo ago | 42 | — | — | — | — |
| 10 | SparkBase Develops private label gift and loyalty card programs for the financial and merchant services industries | $8M | 161 mo ago | 37 | — | — | 2 patents Group incentive sharing platforms for reward distribution and collaborative incentive management | — |
| 11 | LineStream Software for industrial automation control | $8M | 129 mo ago | 6 | Zhiqiang Gao Founder | — | 24 patents Advanced motor control algorithms and state-machine software platform for industrial automation | — |
| 12 | Bloomfilter Project management software for enterprises | $7M | 37 mo ago | 6 | Blake Squires Co-Founder | — | — | — |
| 13 | Docket Operations platform for manufacturers | $5M | 24 mo ago | 6 | Brian Ellis Founder | WordPressMySQLPHP+30 | — | — |
| 14 | Presta Online solutions for digital business lending | $3M | 38 mo ago | 10 | Leopoldo Pena Co-Founder & CEO | MUIReactReact Router+10 | — | — |
| 15 | Heureka Software Unstructured data solutions for enterprise large language models and data governance | $3M | 106 mo ago | 8 | — | — | — | — |
| 16 | CompanionLabs Ad spend optimization solution for businesses | $2M | 95 mo ago | 8 | Brian Deagan ex-Co-Founder | — | — | — |
| 17 | HR Signal Cloud-based platform for employee retention | $2M | 39 mo ago | — | Sagy Cohen Co-Founder & CEO | — | 19 patents Piezoelectric cable sensors for structural health monitoring and vibration detection | — |
| 18 | Votem Blockchain-based mobile application for voting | $1M | 100 mo ago | 5 | Pete Martin Founder / CEO | WordPressMySQLPHP+19 | — | — |
| 19 | Auxilia Cloud-based donor management software for nonprofits | $1M | 12 mo ago | 13 | Aaron Gray Co-Founder | WordPress Block EditorElementorWordPress+25 | — | 1 launch |
| 20 | Verasana Provider of LMS platform for multiple industries | $742K | 37 mo ago | 3 | Charles Luzar Co-Founder & CEO | — | — | — |
| 21 | NimbusWeb Provider of AI powered portals for internal and external collaboration | $700K | 22 mo ago | 45 | Pavel Sher Founder & CEO | WordPressMySQLPHP+23 | — | — |
| 22 | MedaSync AI-based software for data intelligence and workflow automation | $550K | 9 mo ago | 5 | Ryan Edgerly CEO | — | — | 1 partnership |
| 23 | MascotSecret Fan engagement platform for celebrities | $510K | 154 mo ago | — | Jennifer Jeng Co-Founder | — | — | — |
| 24 | Asurint Pre-Employment Background Screening Solutions | $300K | 111 mo ago | 215 215 → 209 (-3%) | — | SanityTurbopackNode.js+26 | — | 1 launch · 2 partnerships |
| 25 | Big River Cloud-based fundraising platform for nonprofit organizations | $275K | 163 mo ago | 4 | Ron Cass Founder & CEO | JavaHighchartsJavaServer Faces+14 | — | — |
| 26 | 90 West Data Data preparation platform for decision makers | $250K | 73 mo ago | — | John Farrall Co-Founder | — | — | — |
| 27 | Gather Employee engagement and communication software | $150K | 69 mo ago | 24 | Alex Hilleary Co-Founder | — | 21 patents Targeted online advertising and user-driven media publishing platforms | — |
| 28 | Groupmatics Online group ticketing platform | $125K | 122 mo ago | 6 | Matt Mastrangelo Founder / CEO | — | — | — |
| 29 | Quixby Personalized E-Commerce solutions | $125K | 157 mo ago | — | Austin Kettner Co-Founder | — | — | — |
Top 12 Enterprise Applications companies in Cleveland
#1
Seed · Cleveland, Ohio · founded 2016 · 5 employees$550Kraised▾
AI-based data intelligence and workflow automation software. Solutions offered by the company include cost analytics, case management, and business intelligence. Cost analytics assists in the identification of high-cost medications and equipment. Case management aids in the management of patient stay, monitoring clinical changes, and service costs, and transitions.
- Aug 2025Seed—
- Feb 2024Seed$1.6M
- Jul 2018Seed$550K
- May 2018Grant (prize money)$25K
#2
Seed · Cleveland, Ohio · founded 2019 · 13 employees$1Mraised▾
Auxilia is a cloud-based donor management software for nonprofit organizations. It provides a platform that allows users to create an account and search for donors in the database. Some of its features are donation & donor management, campaign & fundraising tools, event & ticket management, social media automation, integrated payment processing, etc.
- May 2025Seed$1.4M
- May 2024Seed$425K
- Jun 2021Seed$600K
#3
Series A · Cleveland, Ohio · founded 2013 · 150 employees$42.7Mraised▾
AI-powered platform for fast, high-quality, and cost-effective research. It is a SaaS platform revolutionizing research with AI technology, enabling live digital focus groups, surveys, and in-depth video interviews at scale. The platform offers tools for gathering and analyzing insights, surfacing resonant ideas, and generating summaries. It supports global insights with built-in translation and provides flexible support options. The platform empowers researchers to explore markets, detect blind spots, engage employees, discover pain points, uncover unmet needs, build brands, respond to crises, and build consensus. It is designed for both seasoned researchers and insight seekers, offering a user-friendly design, AI assistance, auto-moderation, and seamless integration. The technology delivers reliable results, enabling users to organize and analyze responses, understand audience segments, and address business challenges with authentic voice.
- Dec 2022Series A$4.2M
- Mar 2020Series A$25M
- Mar 2018Series A$10M
- May 2017Series A$2.2M
#4
Series A · Cleveland, Ohio · founded 2016 · 6 employees$4.6Mraised▾
Operations platform for manufacturers. It offers personalized dashboards for managing shop floor data, connecting people, data, and processes to streamline operations and boost productivity.
- Jun 2024Series A$2.7M
- Nov 2018Seed$1.9M
#5
Seed · Cleveland, Ohio · founded 2023 · 45 employees$700Kraised▾
Provider of AI powered portals for internal and external collaboration. These portals facilitate client, sales, partner, and onboarding processes. The platform incorporates AI agents for automated task management, improving efficiency and streamlining workflows. Customizable templates and integrations with existing systems are offered, enabling seamless personalization and optimization. The solution aims to consolidate various tools into a unified platform, enhancing communication and collaboration across teams and clients. AI-driven features automate tasks such as meeting transcription, proposal generation, and partner onboarding, accelerating processes and improving overall operational efficiency.
- Aug 2024Seed$700K
#6
Series E · Cleveland, Ohio · founded 2008 · 191 employees$33.6Mraised▾
SaaS based staff scheduling and shift management software for the healthcare industry. It predicts and prevents overtime and understaffing while dramatically reducing time spent on scheduling and managing open shifts. Fully integrated with time keeping, HR, clinical and payroll systems, provides a unified view into staffing levels and labor costs across buildings.
- Jun 2022Series E—
- Oct 2018Series D—
- Apr 2016Series D$18.1M
- Feb 2014Series C$7.5M
#7
Series C · Cleveland, Ohio · founded 2006 · 196 employees$102.6Mraised▾
Within3 offers a digital communication platform for the health and life sciences markets. The solution helps healthcare professionals with their networking needs, have real-time meetings or web conferences, and provides an online discussion platform where professionals can discuss at a convenient time.
- Sep 2020Series C$100M
- Jul 2012Series A$2.6M
#8
Seed · Cleveland, Ohio · founded 2022 · 6 employees$7Mraised▾
Project management software for enterprises. It analyzes time series data and supports the software development process. The platform allows teams to measure and visualize product investment against build, run, and maintenance. It includes sprint analysis that provides real-time status on active sprints. It allows users to monitor the project status and team performance in real-time.
- May 2023Seed$7M
- May 2023Venture Debt$1.5M
- 2022Seed$20K
#9
Acquired · Cleveland, Ohio · founded 2008 · 87 employees$18.8Mraised▾
AmpliFund is a cloud-based grant management software for the government. The product is offered for grant seekers to track grant opportunities, funds, goals, planning, execution management, etc., for grantmakers to execute grant progress, automate review process, managing rewards, publish & collect applications, etc., and for grant lifecycle management solution with features as planning program goals, collect & validate the application, monitor grant performance, etc. The product is used by the state government, the federal government, local government, nonprofits, and educational institutions.
- Apr 2020Series A$5.3M
- Jun 2016Series A$10M
- Aug 2015Venture Debt$2M
- Jan 2014Series A$3.5M
#10
Seed · Cleveland, Ohio · founded 2022 · 10 employees$3.3Mraised▾
Online solutions for digital business lending. The platform offers tools for providing risk reports, demographic reports and portfolio management dashboards for organizations. The platform provides tools for customer verifications, business verification, data transfer, and data storage.
- Mar 2023Seed$3.3M
#11
Acquired · Cleveland, Ohio · founded 2012 · 33 employees$13.6Mraised▾
Complion develops software solutions for clinical trial regulatory documentation. The company's flagship product Complion Regulatory e-System can be used by both organizations and trial sites, and is 21 CFR Part 11 compliant for electornic regulatory documentation and e-signatures. Both cloud-based and on-premise options are available.
- May 2020Series B—
- Feb 2019Series B$7M
- Aug 2016Series A$2.9M
- Oct 2015Seed$2M
#12
Series B · Cleveland, Ohio · founded 2014 · 42 employees$13.5Mraised▾
Employstream is a cloud-based employee onboarding solution. The product id an onboarding automation and candidate engagement platform. It also offers various screening services such as drug screens, applicant pre-screening, interview screening, and background checks. Other features include the onboarding platform, employee portal, and career.
- Feb 2020Series B$7M
- Mar 2019Series A$3.5M
- Jan 2019Series A$2.2M
- Aug 2017Seed$850K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Enterprise Applications coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.