Best Enterprise Applications Companies in Des Moines, United States
The 40 best Enterprise Applications companies in Des Moines, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: MakuSafe.
Ranked: Best Enterprise Applications companies in Des Moines
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MakuSafe Provider of a wearable device to improve the safety of industrial workers | $10M | 18 mo ago | Seed | Mark Frederick Co-Founder & CTO | 2016 | WordPressMySQLPHP+24 | 22 patents Industrial IoT solutions for equipment performance optimization and worker health‑safety monitoring. | — |
| 2 | Hummingbirds Online influencer marketing platform | $10M | 22 mo ago | Seed | Emily Steele Co-Founder & CEO | 2019 | Cart FunctionalitySquarespace CommerceSquarespace+27 | 9 patents Privacy-preserving AI-driven biometric authentication using facial and motion‑vision analysis | — |
| 3 | Pitchly Cloud-based platform for enterprise information management and workflow automation | $8M | 28 mo ago | Series A | Ryan Gerhardy Co-Founder & CEO | 2018 | HubSpot CMS HubBootstrapcore-js+26 | 3 patents Privacy-preserving reversible identifier generation for data integration | — |
| 4 | Vertex Cloud-based 3D visualization platform | $3M | 53 mo ago | Seed | Dan Murray Founder | 2017 | HubSpot CMS HubApple iCloud MailGoogle Workspace+18 | 84 patents AI-driven automation of tax compliance, jurisdiction mapping, and virtual assistance. | — |
| 5 | OPCM Provider of opioid risk management solutions for employers | $554K | 86 mo ago | Seed | Mike Vasquez Founder & CEO | 2017 | — | — | — |
| 6 | Gain Compliance Software solutions for data quality and compliance for Insurance | $445K | 120 mo ago | Funding Raised | Jason Jones Co-Founder & CTO | 2016 | — | — | — |
| 7 | InfraLytiks Provider of visual data analytics and automation software | $300K | 65 mo ago | Seed | Tyler Carter Co-Founder | 2016 | — | — | — |
| 8 | Klickle App-based listing platform for multiple local businesses | $200K | 153 mo ago | Seed | Chris Menninga Co-Founder & CEO | 2012 | — | — | — |
Top 12 Enterprise Applications companies in Des Moines
#1
Seed · Des Moines, Iowa · founded 2016 · 30 employees$10Mraised▾
Provider of a wearable device to improve the safety of industrial workers. It is developing a wearable solution that monitors the environmental conditions of the employees working in industries like manufacturing, agriculture, etc to identify the risks in the workplace.
- Feb 2025Seed$1M
- Jul 2020Seed$4M
- Feb 2019Seed$3M
- Dec 2018Seed$50K
#2
Seed · Des Moines, Iowa · founded 2019$10Mraised▾
Online influencer marketing platform. The platform connects businesses with local influencers to build the business. It allows influencers to create content, and access campaigns to promote the business. It caters to industries such as retail, grocery, tourism, and more.
- Oct 2024Seed$5.4M
#3
Series A · Des Moines, Iowa · founded 2018 · 21 employees$8.2Mraised▾
Cloud-based platform for enterprise information management and workflow automation. It offers a database application that enables employees to find and manage information and integrate it into enterprise products and applications using Zapier or enterprise SQL database. It provides a documents application that allows users to create documents in multiple formats and create presentations. It also offers tools for enterprise content and data pipeline management. The offering sectors include banking, legal, finance, consultancy, etc.
- Apr 2024Conventional Debt—
- Apr 2024Series A$970K
- Mar 2023Series A$7M
- Oct 2021Seed$50K
#4
Seed · Des Moines, Iowa · founded 2025$28Kraised▾
Provider of software platform helping furniture professionals reduce waste and rework. The platform supports designers, manufacturers, and other furniture professionals with digital tools to plan, visualize, and specify projects accurately so that materials and components are ordered and used more efficiently. It aims to lower misorders and surplus inventory by improving collaboration and documentation across the furniture project lifecycle, thereby reducing discarded products and overall environmental impact.
- Feb 2026Seed$28K
#5
Seed · Des Moines, Iowa · founded 2017$3Mraised▾
Cloud-based 3D visualization platform. It enables collaboration and sharing of 3D CAD and PLM data. Features include low-code 3D visualization, device agnostic, metadata search & filter, data encryption, and more.
- Mar 2022Seed$3M
#6
Seed · Des Moines, Iowa · founded 2017 · 8 employees$553.6Kraised▾
Opioid Clinical Management provides a platform to manage opioid medication for self-insured employers. The company offers an Opioid Prescription (ORx) suite to optimize employers health outcomes and workforce productivity while reducing health care delivery costs. The company also offers other solutions such as ORx Risk Analyzer, ORx Risk Profiler, and ORx Risk Case Management.
- Jun 2019Seed$203.6K
- Feb 2018Seed$350K
#7
Seed · Des Moines, Iowa · founded 2016 · 11 employees$300Kraised▾
InfraDrone provides visual data analytics and automation software. It allows users to collect, analyze and visualize data using machine learning and artificial intelligence technologies from multiple sources. It provides a web based data visualization platform that allows users to visualize and manipulate data. Its products include Infravieu that provides ML and AI based solutions, Lidar Now that allows users to build algorithms. It collects data from satellites, aircraft, helicopters, drones and vehicles. Clients include Ian Asplund, Aerial Surveyor and more.
- 2021Grant (prize money)$50K
- Apr 2021Grant (prize money)$100K
- May 2017Seed$300K
#8
Funding Raised · Des Moines, Iowa · founded 2016 · 39 employees$445Kraised▾
Gain Compliance provides cloud-based software solutions to insurance companies to improve data quality and compliance. As of Sept 2016, it is in stealth mode.
- Aug 2016Conventional Debt$445K
#9
Seed · Des Moines, Iowa · founded 2012$200Kraised▾
Klickle is an app-based listing platform for multiple local businesses such as restaurants, food trucks, coffee shops, music venues, retail shops & more. The app allows to users to find daily happenings in their preffered local places & eliminate the unwanted advertising. Features include cuareted feedbacks about the local places, full item details, discovery & more. Their app is available for iOS & Android devices.
- Nov 2013Seed$200K
#10
Acquired · Des Moines, Iowa · founded 2000 · 39 employees$60Kraised▾
GCommerce provides SaaS-based supply chain management solutions. It offers solutions for real-time exchange of procurement transaction messages business documents in the Microsoft Azure Cloud. Also, offers a central repository called Virtual Inventory Cloud that enables retailers to check for availability of their suppliers’ products and order non-stocked items either from the web portal or business system. Also, offers AutosoEZ, an e-commerce web platform for automated fulfillment of orders and shipping confirmation and Fulfilment master providing shipping management solution with EDI and API connectivity with marketplaces and retailers. Additionally, offers business analytics solutions and product data management tools like TruSKU and PBEPRO.
- Apr 2012Unattributed—
- Oct 2010Unattributed$60K
- Aug 2010Conventional Debt$150K
- Conventional Debt$4M
#11
Deadpooled · Des Moines, Iowa · founded 2012 · 4 employees$50Kraised▾
Jobsite Unite is a mobile and web Software-as-a-Services platform that streamlines, organizes, and records jobsite communication on construction projects. It lets contractors create a project within the platform and grant access to team members. By checking in to geo-location job sites workers can access contacts, schedules, plans, pictures, and participate in relevant project interactions. Information is delivered through push notifications to the workers mobile device who can collect field information . From the dashboard, managing employees can review progress, track time, assign schedules, view workflow projections and review their manpower outlook. Part of Capital Innovators, St. Louis based accelerator's 2015 spring class.
- Jun 2015Grant (prize money)$50K
- Feb 2015Seed$50K
#12
Deadpooled · Des Moines, Iowa · founded 2016$35Kraised▾
SensientHR is an employee engagement that provides features for pulse surveys, crowdsourcing employee suggestions and discussions, employee recognition, and analytics for engagement insights and benchmarking. Priced at $4/user/month. Clientele includes Fortech solutions, Lucy, namo solutions and others.
- May 2017Seed$35K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Enterprise Applications coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising