Best Enterprise Infrastructure Companies in Tampa, United States
The 53 best Enterprise Infrastructure companies in Tampa, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Reliaquest.
Our analysis of 147 Enterprise Infrastructure companies
$38.8b in tracked funding; 99% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Enterprise Infrastructure companies in Tampa
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Reliaquest 🦄 Developer of agentic AI security operations platform for threat containment 80AI top 15%Funding top 19%Patents top 20%Moat top 22% All 13 signals ▾AItop 15% Fundingtop 19% Patentstop 20% Moattop 22% Innovationtop 26% Producttop 30% Markettop 33% Techtop 33% Talenttop 38% Globaltop 44% Growthbottom 47% Newsbottom 24% Customersbottom 1% AI: Holds AI/ML patents (G06N-family CPC) Funding: Raised $630M across 4 rounds · 4 rounds over 10 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 80/100 | $630M | 15 mo ago | Series E | Brian Murphy Founder & Co-CEO | 2007 | ContentfulBootstrapGSAP+19 | 317 patents Network-based threat detection and mitigation using real-time traffic analysis and security policy enforcement. | 1 job opening · 2 awards |
| 2 | vXchnge Provider of data center colocation solutions | $290M | 105 mo ago | Funding Raised | — | 2013 | WordPressPleskMySQL+10 | — | — |
| 3 | Switch and Data Data center and colocation services in North America | $257M | 202 mo ago | Acquired | Keith Olsen CEO / President | 1998 | — | — | — |
| 4 | OPSWAT Provider of cybersecurity solutions for protecting critical IT and OT environments | $125M | 63 mo ago | Series D | — | 2002 | Craft CMSApple iCloud MailMicrosoft 365+29 | 50 patents Network security gateways, sandboxed file analysis, and automated policy/anomaly detection. | — |
| 5 | SKUx Platform offering AI and blockchain based anti-fraud solutions for e-commerce businesses | $25M | 33 mo ago | Series A | Moshe Joshua Co-Founder / CTO | 2018 | WordPressMySQLPHP+18 | — | 1 launch · 1 partnership · 1 award |
| 6 | Scamnetic Provider of data security solutions 48Talent top 28%AI top 35%Funding top 37%Patents top 42% All 11 signals ▾Talenttop 28% AItop 35% Fundingtop 37% Patentstop 42% Growthtop 45% Moattop 47% Productbottom 48% Techbottom 46% Innovationbottom 45% Globalbottom 40% Marketbottom 32% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated AI: Product described with: ai-powered, artificial intelligence rank vs industry peers · Fliar Intelligence Index 48/100 | $14M | 15 mo ago | Series A | Scott Grushoff Co-Founder & CRO | 2024 | WordPressApple iCloud MailMicrosoft 365+21 | 3 patents Automated detection of fraudulent online transactions using machine‑learning models | 2 launchs |
| 7 | BlockSpaces Platform that connects business applications to blockchain networks 42Funding top 35%Growth top 35%Talent top 38%Moat top 39% All 7 signals ▾Fundingtop 35% Growthtop 35% Talenttop 38% Moattop 39% Techbottom 47% Globalbottom 37% Marketbottom 31% Funding: Raised $14.2M across 7 rounds · 7 rounds over 6 yrs (1.2/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 42/100 | $14M | 13 mo ago | Series A | Rosa Shores Co-Founder & CEO | 2017 | WebflowApple iCloud MailGoogle Workspace+15 | — | — |
| 8 | ThreatWarrior Network monitoring based threat detection and prevention solution | $10M | 63 mo ago | Series A | — | 2017 | — | — | — |
| 9 | Perch Security Collaboration platform to share & consume threat intelligence | $9M | 93 mo ago | Acquired | — | 2016 | — | — | — |
| 10 | Sypris Research Encryption, key management, and IAM solution | $9M | 172 mo ago | Acqui-Hired | John Walsh CEO & President | 2011 | — | — | — |
| 11 | Blue Security Anti-spam and anti-spyware solutions based email security | $3M | 255 mo ago | Deadpooled | Eran Reshef Co-Founder & CEO | 2004 | — | — | — |
| 12 | Raxar Operation management platform | $500K | 113 mo ago | Seed | Alan Akman Co-Founder | 2013 | — | — | — |
Top 12 Enterprise Infrastructure companies in Tampa
#1
Series E · Tampa, Florida · founded 2007 · 777 employees$630Mraised▾
Developer of agentic AI security operations platform for threat containment. The platform facilitates threat detection at the source by connecting technologies. It unifies fragmented telemetry into unified context through automated normalization and correlation. The platform offers capabilities such as attack surface management, digital risk protection, and email phishing defense.
- Apr 2025Series E$500M
- Dec 2021Series D$300M
- Aug 2020Series D$300M
- Jun 2016PE$30M
#2
Series A · Tampa, Florida · founded 2017 · 24 employees$14.2Mraised▾
Platform that connects business applications to blockchain networks. It uses managed infrastructure and configurable drag-and-drop workflows with clicks-or-code. It allows users to connect web2 applications and web3 protocols with little to no code.
- May 2025Series A$2M
- Dec 2024Series A$1M
- Dec 2022Series A$7.2M
- Jan 2022Seed$5.8M
#3
Series A · Tampa, Florida · founded 2024$14.3Mraised▾
Provider of data security solutions. It is an AI-powered platform that offers scam detection and protection services to consumers and businesses, utilizing artificial intelligence technology for individuals and organizations to prevent and detect various types of scams.
- Mar 2025Series A$13M
- Aug 2024Seed$1.4M
#4
Series A · Tampa, Florida · founded 2018 · 30 employees$25.4Mraised▾
Platform offering AI and blockchain based anti-fraud solutions for e-commerce businesses. It provides a solution to manage fraud and double-spend. It also provides product tracking and POS integration solutions.
- Sep 2023Series A$12.4M
- Dec 2022Series A$11M
- Aug 2020Seed$1M
- Nov 2019Seed$1M
#5
Series D · Tampa, Florida · founded 2002 · 88 employees$125Mraised▾
Provider of cybersecurity solutions for protecting critical IT and OT environments. The company offers technologies and products to create comprehensive cybersecurity. These solutions focus on threat prevention, secure data transfer, and safe device access. The company’s platform includes content disarm and reconstruction, multiscanning, vulnerability assessment, and data loss prevention. The company also provides training for partners, customers, and prospects.
- Mar 2021Series D$125M
#6
Funding Raised · Tampa, Florida · founded 2013 · 59 employees$290Mraised▾
VXchnge provides data center colocation solutions. It offers data centres for interconnections that enable digital transformation and hybrid or multi-cloud migrations. Claims that its carrier-neutral data centers are strategically located in high-growth markets and housed in highly fortified facilities that are manned 24x7x365. The clients include SAP, FedEX, CloudMosa, and more.
- Sep 2017Conventional Debt$200M
- May 2015Conventional Debt$90M
#7
Acquired · Tampa, Florida · founded 1998 · 376 employees$257Mraised▾
Switch and Data offers data center, colocation services and internet exchange services. Switch and Data operates 35 high-power density Data Centers and 7 PAIX Peering Internet Exchanges across North America. It offers carrier-neutral data centers are redundant in power, cooling and connectivity. Its customers include Telecom Italia, Telmex, Time Warner Cable, VeriSign, Vonage, Yahoo!, and YouTube among others.
- Sep 2009Conventional Debt$100M
- Mar 2008Conventional Debt$157M
#8
Series A · Tampa, Florida · founded 2017 · 15 employees$10.3Mraised▾
ThreatWarrior provides a solution for network security. The products offered by the company are ThreatWarrior, ThreatQuarantine, and ThreatSQL. ThreatWarrior leverages AI to monitor the network to detect and raise an alert to an anomaly. It automatically recognizes and neutralizes threats. ThreatQuarantine suspends network access when threat events occur, without disrupting other operations. It provides protection against malware, phishing attempts, and insider attacks.
- Apr 2021Series A$10M
- May 2019Seed$300K
- Apr 2019Seed—
- Aug 2018Seed$700K
#9
Acquired · Tampa, Florida · founded 2016 · 28 employees$9Mraised▾
Perch Security provides a collaborative platform to consume and share threat intelligence among the invlolved community organizations and businesses. Platform is a client only software which can optionally integrate with a standard threat intelligence platform (TIP) and streams & alerts over detected threat or malware incident identified by one of the invlolved parties. Claims to function without requiring a SIEM or a dedicated threat intelligence analyst and integrates with any system supporting STIX or TAXII standards. Pricing starts at $11k annually.
- Oct 2018Series A$9M
- Jul 2017Series A—
#10
Acqui-Hired · Tampa, Florida · founded 2011$8.6Mraised▾
Sypris Research provides encryption, key Management, Secure Control Systems and Identity Authentication solution. Product Sypris SYPHER is an FPGA-based Type 1 Crypto solution validated by the NSA to replace crypto ASICs; and Sypris Cryptographic Key Management System (CKMS) for a generation, distribution, and revocation of keys to allow the utilities to manage and distribute cryptographic keys to provide secure communication flows. Main partners include CER IAS, US DoE, GTRI, Oak Bridge Laboratories, OASIS, and Trusted Computing Group. Part of Sypris Electronics which is an integrated systems solutions provider and subsidiary of Sypris Solutions Inc.
- Feb 2012Grant (prize money)$5.1M
- Feb 2011Grant (prize money)$3.5M
#11
Deadpooled · Tampa, Florida · founded 2004$3Mraised▾
Blue Security provided an anti-spam registry to prevent spam and spyware for enterprises and consumers. Product Blue Frog software was a solution to automatically report complaints about spammers for email applications including even web-based Hotmail or Gmail. The company was shut down after a massive cyber-attack in Aug 2006.
- Apr 2005Seed$3M
#12
Seed · Tampa, Florida · founded 2021 · 2 employees$50Kraised▾
Platform offering low code smart contract development and management solutions. It offers a no-code interface that leverages AI to securely audit all digital assets, smart contracts, and customer transactions with data integration and compliance tools for metaverse and AI sectors.
- Jul 2023Seed$50K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Enterprise Infrastructure coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Cloud Computing is moving in the United States
A read on the academic research around Cloud Computing — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,654 United States-affiliated papers.
- Film Independent588
- Microsoft147
- Goddard Space Flight Center135
- University of Washington130
- NSF National Center for Atmospheric Research117
- Scalability51→526
- Software deployment12→253
- Key (lock)16→192
- Operating system45→218
- Workflow3→176
- Scalability14→264
- Key (lock)9→192
- Operating system18→190
- Software deployment9→176
- Analytics8→149
- Key (lock)9→128
- Scalability10→101
- Software deployment2→76
- Operating system13→83
- Big data17→80
Where cloud computing is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing cloud computing patents in the United States
United States cloud computing patent filing is cooling — 6,575 filings from 3,147 assignees (2016–2025), led by IBM, Microsoft, Intel; annual filings 708→574.
- IBM1261
- Microsoft891
- Intel641
- Vmware477
- Oracle381
- Cisco237
- RED HAT185
- Nutanix173
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.