Best Enterprise Infrastructure Companies in Waltham, United States
The 54 best Enterprise Infrastructure companies in Waltham, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Kaseya.
Our analysis of 147 Enterprise Infrastructure companies
$38.8b in tracked funding; 99% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Enterprise Infrastructure companies in Waltham
| # | Company | Disclosed funding | Last round | Employees | Founder | Stage | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Kaseya Cloud based platform offering IT infrastructure monitoring software | $520M | 104 mo ago | 438 | — | Acquired | WordPressMySQLPHP+26 | 52 patents Cloud backup, virtualization state capture, and adaptive rate‑limiting for IT disaster recovery | — |
| 2 | Actifio Cloud-based copy data virtualization software provider | $461M | 95 mo ago | 199 | — | Acquired | — | 78 patents Enterprise data protection and virtualization platforms for backup, replication, and SLA management | — |
| 3 | Infinidat 🦄 Enterprise hybrid storage systems | $325M | 73 mo ago | — | Phil Bullinger CEO | Acquired | DrupalPHPYouTube+26 | — | — |
| 4 | CentrePath Data center networking solutions | $179M | 242 mo ago | 300 | Jim Sullivan CEO | Acquired | — | — | — |
| 5 | Digital Guardian Endpoint Data Loss Prevention | $155M | 86 mo ago | 46 | — | Acquired | DrupalApple iCloud MailMicrosoft 365+33 | — | — |
| 6 | CounterTack Cloud analytics and behavior based malware detection | $113M | 104 mo ago | 144 | — | Series D | — | 33 patents Cybersecurity intrusion detection using DNA-inspired signatures and fuzzy hashing algorithms. | — |
| 7 | Rocket Software Provider of continuous application delivery and hybrid cloud solutions | $98M | 160 mo ago | 438 | — | Acquired | Apple iCloud MailChart.jsVimeo+41 | 55 patents Enterprise data integration, metadata management, and document redaction/security | 2 launchs · 1 partnership · 1 expansion |
| 8 | Incipient Enterprise Data Storage | $95M | 220 mo ago | 65 | — | Series E | — | 6 patents Accelerating data-path and I/O operations with fast-path and caching techniques. | — |
| 9 | Uptycs Cloud-based security analytics solution for anomaly detection and incident response | $93M | 61 mo ago | 131 131 → 135 (+3%) | Uma Reddy Co-Founder CPO | Series C | HubSpot CMS HubYouTubeBrightEdge+22 | — | 2 launchs |
| 10 | CyberX Provider of network monitoring and threat detection solutions | $48M | 87 mo ago | 75 | Nir Giller Co-Founder | Acqui-Hired | — | — | — |
| 11 | Infolibria Hardware and Software for CDN providers | $48M | 295 mo ago | — | David Yates Co-Founder | Acqui-Hired | — | — | — |
| 12 | Nobl9 Developer of a platform managing system performance, uptime, and error budget | $44M | 41 mo ago | 75 | Brian Singer Co-founder | Series B | HubSpot CMS HubApple iCloud MailGoogle Workspace+24 | 5 patents Cloud service level objective monitoring and analytics platform | — |
| 13 | Imprivata Cloud-based authentication and secure communication solutions for enterprises | $40M | 219 mo ago | 546 | Steve Furstenau Director Technical Business Development and Imprivata Founder | Acquired | DrupalApple iCloud MailMicrosoft 365+23 | 76 patents Hardware-backed enterprise authentication and proximity-based presence detection for secure access | — |
| 14 | Watchfire LED displays, digital billboards, and scoreboards for diverse applications | $40M | 181 mo ago | 365 | — | Acquired | WordPressApple iCloud MailMicrosoft 365+37 | — | — |
| 15 | Aveksa SSO & policy based IAM solution | $35M | 160 mo ago | 188 | Vick Viren Vaishnavi Ex-President & CEO | Acqui-Hired | — | 3 patents Enterprise identity and access management: role definition review and entitlement data normalization. | — |
| 16 | XOsoft Replication and high availability solution | $30M | 265 mo ago | 32 | Leonid Shtilman Co-Founder & CEO | Acqui-Hired | — | 2 patents Ensuring data integrity and validation in replicated database systems | — |
| 17 | Randori Cyber risk and vulnerability assessment platforms provider | $30M | 74 mo ago | 52 | — | Acquired | — | 4 patents Autonomous cyber‑security assessment of organizational assets and intrusion‑response readiness | — |
| 18 | Ounce Labs Application source code security-testing solutions | $30M | 214 mo ago | — | Jack Danahy Founder & CEO | Acqui-Hired | — | 9 patents Static source-code analysis tools for detecting security vulnerabilities and race conditions | — |
| 19 | Archivas Provider of data backup and recovery solutions | $28M | 244 mo ago | 50 | Gary Voight ex-President & CEO | Acquired | — | 41 patents Distributed storage management, data privacy, metadata handling, and cluster recovery solutions. | — |
| 20 | Viewfinity Application whitelisting solutions provider | $26M | 153 mo ago | 20 | — | Acquired | — | 7 patents File system virtualization and virtual desktop pool configuration management | — |
| 21 | Q1 Labs Network security software | $25M | 264 mo ago | 45 | — | Acqui-Hired | — | — | — |
| 22 | Confer Endpoint threat detection and response | $25M | 128 mo ago | 25 | — | Acqui-Hired | — | 2 patents Policy‑based detection and control of polymorphic malware in network security systems | — |
| 23 | Dynatrace Cloud and AI based enterprise observability and monitoring platform | $22M | 95 mo ago | 1,168 | Rick Mcconnell CEO of Dynatrace | Public | Apple iCloud MailNode.jsThree.js+25 | 273 patents Application performance monitoring, root-cause analysis, and automated software delivery optimization | — |
| 24 | Noetic Cloud based platform offering cyber risk assessment solutions | $20M | 45 mo ago | 53 | Paul Ayers Co-Founder & CEO | Acquired | — | 2 patents Secure data trust frameworks and ergonomic wearable joint support devices | — |
| 25 | Okena Network access control solution for HIDS & endpoint security | $17M | 299 mo ago | 52 | — | Acquired | — | — | — |
| 26 | Interactive Supercomputing Parallel computing solution | $16M | 225 mo ago | — | Alan Edelman Founder & CEO | Deadpooled | — | — | — |
| 27 | Xkoto Replication and Virtualization of Data. | $13M | 209 mo ago | — | — | Acquired | — | — | — |
| 28 | Kwicr SaaS based mobile delivery network | $11M | 140 mo ago | — | Kanti Chakrabarti Founder & Ex-MD | Acqui-Hired | — | — | — |
| 29 | Sentrix Context Aware cloud based Website security | $10M | 142 mo ago | 11 | — | Acqui-Hired | — | — | — |
| 30 | V.I. Laboratories Threat intelligence software | $8M | 224 mo ago | — | Nathaniel Cohen Founder | Series B | — | 131 patents Patents concentrated in health & consumer products | — |
| 31 | Gold Wire Technology Network compliance and access management solutions porvider | $6M | 317 mo ago | — | Thomas Browne CEO | Acqui-Hired | — | — | — |
| 32 | Leostream Cloud-based virtual desktop solutions provider | $5M | 200 mo ago | 14 14 → 20 (+43%) | Karen Gondoly CEO | Series A | WordPress Block EditorWordPressApple iCloud Mail+40 | 9 patents Dynamic user-to-resource assignment and remote desktop virtualization management | — |
| 33 | Netegrity IAM solution to secure access to the web applications and enterprise resources | $5M | 342 mo ago | 400 | Michael Gregoire CEO | Acquired | — | 2 patents Network authentication and federated identity access control mapping | — |
| 34 | Exoprise Cloud based application performance monitoring | $4M | 162 mo ago | 4 | — | Acquired | WordPressMySQLPHP+24 | — | — |
| 35 | CloudFloor Realtime analytics dashboard to monitor cloud infrastructure | $3M | 186 mo ago | — | Jaime Ellertson CEO & Founder | Acquired | — | — | — |
| 36 | OnePage Cloud based secure messaging system for enteprise | $3M | — | 7 | Judit Sharon CEO | Deadpooled | — | — | — |
| 37 | Virtual Software Systems Virtualization based software-defined secure computer | — | 109 mo ago | — | John Conway President & CEO | Deadpooled | — | — | — |
| 38 | HiSoftware Platform offering a range of tools and technologies to manage regulatory compliance. | — | 247 mo ago | 53 | Kurt Mueffelmann President & CEO | Acqui-Hired | — | — | — |
| 39 | Findability Sciences Big data and AI-based cognitive computing solutions | — | — | 25 | Anand Mahurkar Founder & CEO | Unfunded | — | — | 1 launch · 2 awards |
Top 12 Enterprise Infrastructure companies in Waltham
#1
Series B · Waltham, Massachusetts · founded 2019 · 75 employees$44.4Mraised▾
Developer of a platform managing system performance, uptime, and error budget. The platform streamlines reliability using service level objectives. It integrates with existing workflows, providing business and user context. The platform offers comprehensive service level objective management solutions to optimize performance and ensure uptime. It facilitates integration with tools to enhance reliability.
- Jan 2023Series B$15.8M
- Feb 2021Series B$21.1M
- Sep 2019Series A$7.5M
#2
Acquired · Waltham, Massachusetts · founded 2019 · 53 employees$20Mraised▾
Cloud based platform offering cyber risk assessment solutions. It also provides a cyber asset management platform for providing a proactive approach to cyber assets, controls management and security teams to understand and optimize the cybersecurity posture and enterprise ecosystem.
- Oct 2022Series A—
- Jul 2021Series A$15M
- Seed$5M
#3
Series C · Waltham, Massachusetts · founded 2016 · 131 employees$93Mraised▾
Cloud-based security analytics solution for anomaly detection and incident response. The security use cases include detection and remediation, investigation, IT compliance, and collaborative response and operations use cases include asset discovery and inventory, debugging and diagnostics, configuration visibility, and continuous monitoring.
- May 2021Series C$50M
- Jun 2020Series B$30M
- Jun 2018Series A$10M
- Apr 2016Seed$3M
#4
Acquired · Waltham, Massachusetts · founded 2009 · 199 employees$461Mraised▾
Actifio is a cloud-based copy data virtualization software provider. It provides a storage system optimized for managing copies of production data, eliminating redundant silos of IT infrastructure and data management applications. A single solution can now be deployed to replace one or all backup software, disaster recovery, business continuity, and test development tools. Also, this data source can now be used as the platform for search, compliance, and analytics tools.
- Aug 2018Series F$100M
- Mar 2014Series E$100M
- Feb 2013Series D$50M
- Nov 2011Series C$33.5M
#5
Acquired · Waltham, Massachusetts · founded 2011$325Mraised▾
Enterprise hybrid storage systems. It is data protection and cyber resilience solution that helps protect against ransomware, malware, and cyberattacks. It provides storage in the range of petabytes in a single blade giving mainframe capabilities. The storage is built using low-cost hardware and suited for big data analytics, object storage, and more.
- Jun 2020Series D—
- Jan 2019Grant (prize money)$443.2K
- Oct 2017Series C$95M
- Apr 2015Series B$150M
#6
Acquired · Waltham, Massachusetts · founded 2003 · 46 employees$154.7Mraised▾
Digital Guardian (Previously Verdasys) provides advanced data protection solutions for endpoints. It protects companies’ sensitive data from both insider and cyber threats. Verdasys secures the sensitive data of the world’s most security-conscious organizations by protecting sensitive data from leaving an organization at the point of risk, namely the endpoint. Digital Guardian by Verdasys can empower businesses to detect and stop both insider and cyber attacks with a single platform. It caters various industries such as logistics, financial services, among others
- Apr 2019Series D$30M
- Dec 2015Series D$66M
- Jun 2014Conventional Debt$5M
- Mar 2014Series C$12M
#7
Acquired · Waltham, Massachusetts · founded 2000 · 438 employees$520.1Mraised▾
Cloud based platform offering IT infrastructure monitoring software. It allows monitoring, management, and maintaining distributed IT infrastructures remotely with an integrated web based platform. It automatically updates security patches and software updates. Other features include audit and inventory tracking, utilization monitoring, backup, security review, and desktop migration. It also provides MFA based SSO solution for secure access to the enterprise IT systems and apps with features such as IDaaS, password auditing, automation, and credential management.
- Nov 2017PE$44.8M
- Mar 2016PE$709.2M
- Sep 2008Grant (prize money)$99.7K
- PE—
#8
Series D · Waltham, Massachusetts · founded 2007 · 144 employees$112.9Mraised▾
CounterTack Sentinel is an end-point monitoring solution in a hub & spoke architecture. The end-point clients send OS, memory, process and networking activities data to a central command center which keeps analyzing for malicious activities based on malware behaviors. CounterTack was recently listed in “Cool Vendors” in the Gartner Cool Vendors for Application and Endpoint Security 2014 report.
- Nov 2017Series D—
- Jun 2017Series D$20M
- Nov 2016Series C$10M
- Sep 2015Series C$17.9M
#9
Acquired · Waltham, Massachusetts · founded 2000 · 300 employees$179Mraised▾
CentrePath, Inc. develops and markets data center networking solutions to healthcare, financial services, media, and entertainment industries. The company's product, Magellan DataPath Manager, allows users to perform event correlation, root cause identification, impact analysis, and monitor performance. The company also offers network staging and certification, space design, fiber testing, project management, and network transport services. It has strategic alliances with IBM, Cisco Systems, Ciena, and AT&T. The company's clientele includes Community Health Network and Fifth Third Bank.
- Apr 2006Series C$10M
- Sep 2005Series C$5M
- Mar 2004Series C$4M
- Feb 2001Series C$120M
#10
Acquired · Waltham, Massachusetts · founded 2018 · 52 employees$29.8Mraised▾
Randori offers cyber risk and vulnerability assessment platforms. The company's offering include Randori Recon and Randori Attack. The company's solution has applications in attack surface management, cloud migration, shadow IT risk, etc.
- Apr 2020Series A$20M
- Oct 2018Series A$9.8M
#11
Series E · Waltham, Massachusetts · founded 2001 · 65 employees$94.7Mraised▾
Incipient engages in the development of enterprise-class storage, storage area networks (SAN) storage virtualization, and automated data migration software solutions. It offers Incipient Automated Data Migration Software for data migration projects, such as data center moves, storage array refreshes, application tiering, and storage resource balancing; and Incipient Network Storage Platform Software, which combines storage virtualization technology with management allowing customers to move data across their SAN environment. The company also offers data migration, automated storage provisioning, data copy services, and data protection solutions. It serves data migration, storage virtualization, storage provisioning, storage area networks management, and copy services markets. The company distributes its products through channel partners. Incipient, Inc. was founded in 2001 and is headquartered in Waltham, Massachusetts.
- Feb 2008Series E$15.6M
- Jan 2006Series D$24M
- Jan 2005Series C$20M
- Sep 2003Series B$25M
#12
Acquired · Waltham, Massachusetts · founded 1990 · 438 employees$97.7Mraised▾
Provider of continuous application delivery and hybrid cloud solutions. The platform streamlines the continuous integration and delivery of applications. Its hybrid cloud solution allows users to connect applications, workflows, and data between different cloud environments. Features include workflow automation and reporting tools, data protection, archive and backup, data migration, dashboards, change management, more.
- Mar 2013Venture Debt$5M
- Feb 2012Venture Debt$15M
- Sep 2009Series C$91.9M
- Feb 2008Series B$5M
Funding & investor landscape
Ascent Venture Partners3 roundsNotable founders
Market landscape — 10 sub-themes by coverage
Share of Enterprise Infrastructure coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Cloud Computing is moving in the United States
A read on the academic research around Cloud Computing — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,654 United States-affiliated papers.
- Film Independent588
- Microsoft147
- Goddard Space Flight Center135
- University of Washington130
- NSF National Center for Atmospheric Research117
- Scalability51→526
- Software deployment12→253
- Key (lock)16→192
- Operating system45→218
- Workflow3→176
- Scalability14→264
- Key (lock)9→192
- Operating system18→190
- Software deployment9→176
- Analytics8→149
- Key (lock)9→128
- Scalability10→101
- Software deployment2→76
- Operating system13→83
- Big data17→80
Where cloud computing is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing cloud computing patents in the United States
United States cloud computing patent filing is cooling — 6,575 filings from 3,147 assignees (2016–2025), led by IBM, Microsoft, Intel; annual filings 708→574.
- IBM1261
- Microsoft891
- Intel641
- Vmware477
- Oracle381
- Cisco237
- RED HAT185
- Nutanix173
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.