Best Enterprise Software Companies in Palo Alto, United States
The 51 best Enterprise Software companies in Palo Alto, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: phantom.
Ranked: Best Enterprise Software companies in Palo Alto
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | phantom Phantom is a purpose-built, community-powered security automation, and orchestration platform. | $23M | 114 mo ago | Acquired | — | 2014 | — | 73 patents Autonomous vehicle perception and control: lane reconstruction, trajectory prediction, data augmentation, interior partitioning. | — |
| 2 | genoox Genoox uses the power of the community to make genomic data actionable with a mission to create the largest… | $20M | 27 mo ago | Series B | — | 2014 | TypeScriptTailwind CSSZone.js+16 | — | — |
| 3 | Vysr Developer of browser plug-in for web browsers | $2M | 219 mo ago | Deadpooled | Guda Venkatesh Founder & CEO | 2006 | — | — | — |
| 4 | Westlight AI Limited information available 6Funding bottom 48%Talent bottom 45%Global bottom 29%Market bottom 10% All 4 signals ▾Fundingbottom 48% Talentbottom 45% Globalbottom 29% Marketbottom 10% Funding: Raised $1.0M across 2 rounds · 2 rounds over 6 yrs (0.3/yr) Talent: 1 named leader on record rank vs industry peers · Fliar Intelligence Index 6/100 | $1M | 67 mo ago | Funding Raised | Aaron Greenblatt Founder & CEO | 2019 | — | — | — |
| 5 | 500 miles 500 Miles is a data-driven recruiting platform that connects students and young professionals to startups | — | — | Deadpooled | — | 2014 | — | — | — |
| 6 | Accellion The Accellion secure file sharing and governance platform empowers millions of corporate executives… | — | — | — | — | 1999 | — | 4 patents Secure enterprise file transfer and communication platforms for distributed systems | — |
| 7 | aiternis Aiternis is a global clinical blockchain platform and marketplace. | — | — | Deadpooled | — | 2017 | — | — | — |
| 8 | alicanto Alicanto offers collaborative sales and cross-promotional marketing solutions for small and medium-sized… | — | — | Deadpooled | — | 2011 | — | — | — |
Top 4 Enterprise Software companies in Palo Alto
#1
Series B · Palo Alto, California · founded 2014 · 40 employees$20Mraised▾
Developer of genomic analytics designed to translate complex genetic data into useful clinical information. The company's platform uses artificial intelligence and machine-learning algorithms to analyze rare genetic mutations and predict the probability that is responsible for a condition, enabling clinics to handle data from genetic screening with less time and improve patient outcomes with increased accuracy and efficiency.
#2
Acquired · Palo Alto, California · founded 2014 · 104 employees$22.7Mraised▾
Provider of a security automation and orchestration platform created to integrate with existing security technologies in order to provide a layer of connective tissue between them. The company's security automation and orchestration platform automatically triages events to eliminate noise from the workload, pre-fetches threat intelligence to support decision making, orchestrates complex workflows to improve efficiency and precision, and automates repetitive tasks to multiply team efforts and focus company's attention on mission-critical decisions, enabling organizations to respond to incidents at machine speed.
#3
Funding Raised · Palo Alto, California · founded 2019 · 3 employees$1Mraised▾
Devloper of data provenance systems designed to democratize cyber resilience for the distributed professional workforce. The company's systems re-conceptualize data access and control through novel applications of AI and other technologies, enabling clients to get data in applications that are sensitive, monitored, and controlled across a diverse set of hardware and software platforms.
- Dec 2020Conventional Debt$250K
- Feb 2020Grant (prize money)$750K
#4
Deadpooled · Palo Alto, California · founded 2006$2Mraised▾
Developer of software to integrate Web services. The company provides a platform enabling consumers to use and share any of their Web services in any browsing context. The company's open platform enables developers to add and integrate services and networks that users can tap into as they travel the Web.
Funding & investor landscape
Market landscape — 10 sub-themes by coverage
Share of Enterprise Software coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.