Best Gastroenterology Companies in United Kingdom
The 37 best Gastroenterology companies in United Kingdom in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Quell.
- Gastroenterology Market Projected to Reach USD 53.10 Billion by 2031,
Ranked: Best Gastroenterology companies in United Kingdom
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Quell Developer of engineered regulatory T cell therapies for immune diseases | $344M | 44 mo ago | 18 | Giovanna Lombardi Co-Founder | TurbopackNode.jsSalesforce+13 | Top 10M | — | — |
| 2 | OMass Therapeutics Developer of therapeutics for immunological and orphan diseases | $166M | 40 mo ago | 36 36 → 78 (+117%) | Carol Robinson Co-Founder | WordPressApple iCloud MailMySQL+21 | Top 10M | 16 patents Small‑molecule modulators of MC2R, GPR65 GPCRs and SMO hedgehog pathway therapeutics | — |
| 3 | Redx Pharma Developer of small molecule medicines for fibrotic disease and oncology | $163M | 34 mo ago | 89 | Lisa Anson CEO | WordPressMySQLPHP+20 | Top 10M | 423 patents Small‑molecule kinase inhibitors targeting ROCK, DDR1/2, and Wnt pathways | — |
| 4 | Resolution Therapeutics Developer of macrophage cell therapy for the treatment of inflammatory & liver diseases | $120M | 23 mo ago | 6 | John Campbell Co-Founder | WordPressApple iCloud MailMicrosoft 365+22 | Top 50M | 17 patents Patents concentrated in chemistry & materials | — |
| 5 | Sitryx Biotechnology company focused on immunometabolism, developing therapies | $69M | 38 mo ago | 17 | Paul-Peter Tak Co-Founder & Director | Node.jsNext.jsReact+8 | Top 50M | — | — |
| 6 | Enterobiotix Developer of microbiome-based therapeutics for multiple disease targets 50Growth top 13%Funding top 25%Product top 30%Moat top 39% All 11 signals ▾Growthtop 13% Fundingtop 25% Producttop 30% Moattop 39% Talentbottom 49% Globalbottom 42% Innovationbottom 41% Techbottom 41% Patentsbottom 37% Marketbottom 36% Newsbottom 22% Growth: Headcount 11 → 28 (+155%) across vintages · Fresh capital in last 24 mo Funding: Raised $66.0M across 10 rounds · 10 rounds over 9 yrs (1.1/yr) rank vs industry peers · Fliar Intelligence Index 50/100 | $66M | 4 mo ago | 28 28 → 44 (+57%) | James McIlroy Founder & CEO | Cart FunctionalitySquarespace CommerceSquarespace+13 | Top 50M | 10 patents Medical collection containers for biological samples | — |
| 7 | VHsquared Designs and develops antibodies engineered to be stable in the gastrointestinal (GI) tract. | $58M | 62 mo ago | 8 | Rod Richards CEO | — | — | 62 patents Design and delivery of therapeutic peptides with protease‑cleavable linkers for drug development. | — |
| 8 | Topivert Kinase Inhibitors for inflammations in GI tract and the eye | $40M | 152 mo ago | 4 | — | — | — | — | — |
| 9 | Ochre Bio Developer of ribonucleic acid therapies for treating chronic liver diseases | $40M | 47 mo ago | 11 | Quin Wills Co-Founder & CEO | WordPressApple iCloud MailGoogle Workspace+26 | Top 10M | — | — |
| 10 | Shift Bioscience Developer of drugs that reprogram mitochondrial (mtDNA) mutations | $29M | 23 mo ago | 3 | Daniel Ives Founder & CEO | WordPressApple iCloud MailGoogle Workspace+23 | Top 50M | 5 patents AI-driven temporal property prediction for molecules and mitochondrial DNA variant analysis | — |
| 11 | Atlantic Healthcare Specialty pharma company that has Phase III programmes targeting gastrointestinal disorders | $24M | 125 mo ago | 12 | — | — | — | — | — |
| 12 | Creo Medical Developer of electrosurgical system and range of flexible endoscopic instruments | $21M | 26 mo ago | 108 | Craig Gulliford CEO | PHPEngintronNginx+12 | Top 5M | 1,736 patents Surgical energy devices for RF/microwave tissue cutting, coagulation, and ablation | — |
| 13 | Medicina Products for enteral feeding and stoma | $10M | 152 mo ago | 22 | Ken Harrison Founder | WordPressMySQLPHP+24 | Top 10M | — | — |
| 14 | Functional Gut Group Developer of a diagnostic test for gut health | $7M | 17 mo ago | 8 | Anthony Hobson Founder | WordPressMySQLPHP+29 | Top 10M | — | — |
| 15 | Cyted Leader in non-endoscopic diagnostics for digestive health, enabling early disease detection and access to… 53Talent top 28%Funding top 33%Patents top 33%Growth top 35% All 9 signals ▾Talenttop 28% Fundingtop 33% Patentstop 33% Growthtop 35% Innovationtop 37% Moattop 46% Techbottom 45% Globalbottom 40% Marketbottom 32% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $6.6M across 6 rounds · 6 rounds over 6 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 53/100 | $7M | 12 mo ago | — | Maria Odonovan Co-Founder & CMO | WebflowSalesforceGSAP+15 | Top 10M | 16 patents Endoscopic cell‑sampling devices for esophageal tissue and Barrett's diagnosis | — |
| 16 | Bloomsbury Genetic Therapies Provider of gene therapy commercialization services | $6M | 49 mo ago | 4 | Adrien Lemoine Co-Founder & CEO | — | — | — | — |
| 17 | Enteral Access Technologies Developer of a device for safe nasogastric tube placement | $5M | 10 mo ago | — | George Gallagher Founder & CEO | — | — | — | — |
| 18 | Yaqrit Liver dialysis device | $5M | 66 mo ago | 14 | Rajiv Jalan Founder & CSO | — | — | 21 patents Patents concentrated in health & consumer products | — |
| 19 | 11health Sensor based alerts for ostomy patients | $2M | 132 mo ago | 3 | Adam Bloom Co-Founder | — | — | — | — |
| 20 | BeamLine Diagnostics Provider of bedside pre-screening technology for cancer | $1M | 111 mo ago | 7 | — | — | — | 10 patents FTIR spectral analysis for cell sorting and disease detection diagnostics | — |
| 21 | Oxford MEStar Developer of novel scaffolds for tissue engineering and stem cell delivery | $930K | 120 mo ago | 8 | Zhanfeng Cui Founder & Chairman | — | — | — | — |
| 22 | Curileum Discovering and validating novel stem cell targets to regenerate the mucosal barrier and restore health to… | $466K | 89 mo ago | 6 | Jeff Moore Founder & CEO | — | — | — | — |
| 23 | DiagNodus Developing non-invasive diagnostic test for colorectal disease conditions | $167K | 151 mo ago | 2 | Alexandre Loktionov CEO | — | — | 12 patents Non‑invasive colorectal mucus sampling for gastrointestinal disease diagnostics | — |
| 24 | BioMe Oxford Provider of a gut-sampling device for the diagnostics of gastrointestinal disorders | $33K | 120 mo ago | 4 | — | — | — | 15 patents Medical devices for gastrointestinal sampling and analysis | — |
| 25 | AgPlus Diagnostics Handheld technology platform for disease diagnosis | — | 119 mo ago | 8 | Robert Porter Founder & CTO | — | — | 11 patents Patents concentrated in transport & manufacturing processes | — |
Top 12 Gastroenterology companies in United Kingdom
#1
Series B · Edinburgh, Scotland · founded 2017 · 28 employees$66Mraised▾
Developer of microbiome-based therapeutics for multiple disease targets. The company is engaged in developing an integrated anaerobic system which comprises of a closed system collection and processing benchtop system that will allow therapies to be produced outside of cleanrooms and in anaerobic environments. It aims to offer microbiome therapy to patients suffering from Inflammatory Bowel Disease and other diseases related to the gut.
- Apr 2026Series B$25M
- Mar 2026Series B$5.3M
- Jul 2025Series B$1.4M
- Mar 2024Series B$1.3M
#2
Seed · Liverpool, England · founded 2018$4.6Mraised▾
Developer of a device for safe nasogastric tube placement. The device DoubleCHEK uses pH and CO2 indicators to confirm correct tube position, reducing the risk of misplacement and lung damage. It features a closed system to maintain infection control and is compatible with existing equipment. The system simplifies the process, eliminating the need for pH paper and messy aspiration.
- Nov 2025Seed$657.9K
- May 2025Seed$186.1K
- Apr 2024Seed$473K
- Apr 2023Seed$2.3M
#3
Series B · Edinburgh, Scotland · founded 2017 · 6 employees$119.9Mraised▾
Developer of macrophage cell therapy for the treatment of inflammatory & liver diseases. The company has developed cell therapies based on its proprietary platform of macrophage biology, cell engineering, and manufacturing processes. The therapeutic solutions enhance body immunity power and provide prevention solutions for inflammatory organ damages. It also helps in sterilising any wounds and promotes organ repair.
- Oct 2024Series B$84.3M
- Dec 2020Series A$35.6M
#4
Series B · Cambridge, England · founded 2018$6.6Mraised▾
Cyted Health is a gastrointestinal health company pioneering non-endoscopic diagnostics to detect diseases early and provide access to care for everyone. Their technologies aim to revolutionize diagnostics and improve patient care.
- Sep 2025Series B$43.8M
- Dec 2020Series A$2.9M
- Oct 2020Series A$817.1K
- Aug 2020Series A$2M
#5
Seed · Letchworth Garden City, England · founded 2017 · 3 employees$28.6Mraised▾
Developer of drugs that reprogram mitochondrial (mtDNA) mutations. The company is developing novel drug molecules that can treat diseases where mitochondrial DNA (mtDNA) damage is identified. It has identified small drug agonists able to trigger mitochondrial gene shifting by metabolic reprogramming in specific tissues. The company claims that these molecules can treat age-related diseases such as neurodegenerative diseases or coronary heart disease.
- Oct 2024Seed$16M
- Aug 2022Seed$1.1M
- Jun 2022Seed$10.6M
- Feb 2022Seed$297.7K
#6
Acquired · Manchester, England · founded 2014 · 8 employees$7.4Mraised▾
Developer of a diagnostic test for gut health. The product includes Breath testing for small intestinal bacterial overgrowth, Methane Breath CH4ECK for detecting abnormal methane levels, ZepHr is a reflux monitoring system, Motion testing for oesophageal function disorders, and Lower bowel testing for disorders of the pelvic floor. The company also has inSIGHT Ultima System and BioVIEW acquisition and analysis software.
- Apr 2025PE$7.4M
#7
Acquired · Liverpool, England · founded 2010 · 89 employees$163.5Mraised▾
Developer of small molecule medicines for fibrotic disease and oncology. The company focuses on novel compounds against biologically or clinically validated targets. It has an extensive programme of pre-clinical research focused on Discoidin Domain Receptors. The company’s core strengths are in medicinal chemistry, translational science, and clinical development.
- Oct 2023Post IPO$17.2M
- May 2022Post IPO$42.6M
- Dec 2020Post IPO$34.1M
- Apr 2020Post IPO—
#8
Series B · London, England · founded 2019 · 18 employees$344.2Mraised▾
Developer of engineered regulatory T cell therapies for immune diseases. This clinical-stage organization focuses on modifying a patient's own regulatory T cells to restore immune balance. These therapies aim to address conditions involving autoimmunity, chronic inflammation, and organ transplant rejection by dampening immune responses and preventing tissue damage. The approach utilizes cellular engineering to regulate immune activity and manage severe inflammatory disorders.
- Jan 2023Series B$24.1M
- Mar 2022Series B$57.9M
- Nov 2021Series B$156M
- Dec 2020Series A$34.9M
#9
Series B · Oxford, England · founded 2016 · 36 employees$166.2Mraised▾
Developer of therapeutics for immunological and orphan diseases. The company's technology platform, called OdyssION, allows them to study protein assemblies and the interactions of targets within their native biological ecosystems with high resolution. The company is advancing a pipeline of small molecule therapeutics primarily for immunological and orphan diseases, using genetic and immune signature stratification to select targets with low translation risk.
- May 2023Series B$12.4M
- Apr 2022Series B$100M
- Feb 2020Series A$35.9M
- 2018Series A$17.9M
#10
Public · Chepstow, Wales · founded 2003 · 108 employees$20.8Mraised▾
Developer of electrosurgical system and range of flexible endoscopic instruments. The first instrument performs flexible endoscopic dissection of tissue abnormalities in the GI tract. Future areas of treatment include laparoscopic surgery and treatment of certain cancerous lesions.
- Jul 2024Post IPO$250K
- Dec 2019Post IPO$55.6M
- Jul 2018Post IPO$64.2M
- Jan 2017Grant (prize money)$641K
#11
Series B · Oxford, England · founded 2018 · 17 employees$69Mraised▾
Biotechnology company focused on immunometabolism, developing therapies. The company exploits the link between immune function and metabolism to create first-in-class, disease-modifying drugs aiming for sustained remission. Their science regulates metabolic pathways in immune cells to restore balance disrupted in chronic conditions.
- Jul 2023Series B$39M
- Dec 2022Series A$3.7M
- Sep 2022Series A$11.8K
- Mar 2020Series A$9.6M
#12
Series A · Oxford, England · founded 2019 · 11 employees$39.7Mraised▾
Developer of ribonucleic acid therapies for treating chronic liver diseases. Research activities focus on identifying drug targets through the analysis of human biological data and tissue models. The organization utilizes computational platforms to predict therapeutic outcomes and creates genetic medicines to address liver fibrosis and cirrhosis. These efforts aim to restore organ function and improve patient survival by targeting specific biological pathways involved in disease progression.
- Oct 2022Series A$30M
- Jun 2021Seed$9.6M
- Mar 2020Seed$125K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Gastroenterology coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising