Best Genomics Companies in Missouri, United States

Developer of next-generation trait delivery technology for higher-yielding crops and sustainable agriculture. It offers a platform that places beneficial traits in the chloroplast of plant cells, enhancing crop performance. This approach simplifies product development, improves product effectiveness, and creates new market opportunities. The technology enables crops to better withstand insects, diseases, and weeds, leading to higher yields. By focusing on chloroplast trait introduction, they address challenges like pest resistance, trait outcrossing, and complex trait integration. This platform offers solutions for seed companies, providing a valuable tool to help growers meet the nutritional needs of a growing population. The technology supports sustainable agriculture by reducing the need for chemicals and enhancing crop resilience.

Funding rounds

• Oct 2025Series B$5.8M
• Nov 2021Series A$7.1M
• May 2021Series A$3.2M
• Mar 2021Series A$2.4M

Founders & team

Jeffrey StaubFounder and Chief Scientist

Investors

TechAccel, The Yield Lab, St. Louis Economic Development Partnership, St. Louis Arch Angels, Missouri Technology, Helix Center

Developer of non-invasive biomarker tests for colorectal cancer. The flagship assay analyzes stool samples for a panel of disease-associated mRNA biomarkers using a proprietary diagnostic algorithm to detect colorectal cancer. The company plans that its assay will be used to screen patients in need of a more invasive colonoscopy.

Developer of biomaterials using dandelion as a sustainable resource. The company focuses on replacing petrochemical polymers with dandelion biomaterials. It promotes regenerative agriculture practices and aims to eliminate emissions from daily products. The company offers natural rubber, resin, inulin, and fiber.

Funding rounds

• May 2025Grant (prize money)$600K
• Sep 2023Grant (prize money)$600K
• Apr 2021Grant (prize money)$100.1K
• Apr 2020Series A$4.8M

Founders & team

Dan SwigerFounder & CEO

Investors

United States Department of Agriculture, Missouri Technology, iSelect Fund, Lagomaj

Cicadea Biotech is a developer of PCR-based assays. The company has developed pathogen detection RT-PCR kits with customized assays to detect specific DNA fragments of pathogenic microbes in food, animal feed, water, environmental and industrial products. It also provides services like custom PCR assays, high throughput PCR testing, digital PCR assays to detect cancer mutation, and high throughput DNA extraction.

Funding rounds

• Apr 2025Grant (prize money)$305K

Founders & team

Lucy BurnsFounder & CEO

Investors

National Science Foundation

Developer of sustainable agriculture technology for farm profitability and promoting renewable energy. It revolutionizes winter cropping, empowering farmers to balance sustainability and profitability, enhancing long-term land health. It offers a solution to utilize idle winter fields, turning downtime into a productive season with a third cash crop. The crop integrates into existing operations, supporting economic and sustainability goals, contributing to renewable energy efforts and responsible agricultural practices. The company provides a low-risk, hassle-free solution with seamless integration, and a guaranteed end-market. They use dedicated partnerships to ensure direct grain pickup, providing a reliable end market for farmers and enabling participation in regenerative agriculture programs.

PierianDx is a provider of genetic tests for individualized diagnosis of multiple diseases. It provides patient-specific diagnosis and treatments based on an individual’s DNA. The company's proprietary Clinical Genomicist Workstation software is a cloud-based platform used for managing next-generation sequencing processes. The platform works in six phases including Case accessioning, sequencing, analysis, draft report, final report, and integration in Electronic Health Record.

Funding rounds

• Nov 2021Conventional Debt—
• Nov 2021Series C$30M
• Jun 2021Series B—
• Oct 2019Series B$27M

Founders & team

Rakesh NagarajanFounder

Investors

Health Catalyst Capital, ARUP Laboratories, Inova, Meyer and Co, ATW Partners, RTI International

Tech stack

Hubspot Cms HubBugherdGoogle AdsHubspotSlickJquery

Appistry tools streamline the analysis of genomic data and make it easier for clinical labs, research institutions, and hospital practices to act on. The company provides CloudDx, a cloud-based system that helps institutions conduct patient-centered translational research and hospitals to implement genome-scale tests based on next-generation sequencing (NGS) into routine patient care. The company also offers Cancer Genome Analysis Suite that provides a set of integrated tools to address issues in getting results from cancer genome NGS datasets.

Funding rounds

• Jan 2016Series E$4.1M
• Feb 2015Conventional Debt$10.2M
• Feb 2014Conventional Debt$10.3M
• Aug 2013Series E$4.9M

Founders & team

Guerry SemonesCo-FounderMichael Gronerex-Co-Founder

Investors

Stuart Mill Venture Partners, Lewis & Clark Capital, Arsenal Capital Management

Innovative assay kits and biosensors for research, diagnostics, and therapeutics. The company provides cutting-edge innovations for analysis and biosensors, offering a range of patented assay platforms. These technologies are adapted for detecting macromolecules, including cAMP, tryptophan, and insulin. The company focuses on providing innovative assay kits and biosensors needed by academic research laboratories, point of care testing, pharmaceutical companies, as well as medical and environmental research markets. The company's core proprietary technologies include Bridge-It, a DNA-binding protein assay platform, and PINCER, a biosensor, bioassay, and biochip platform. These technologies are used to quantify biologically and therapeutically important macromolecules, including DNA, biomarkers, hormones, antibodies, intracellular signaling molecules, protein-protein complexes, bacteria, fungi, and viruses. The company develops new high-affinity capture reagents for research, diagnostic, and therapeutic use, including anti-angiogenesis related therapies.

Funding rounds

• Jul 2020Grant (prize money)$970.7K
• Sep 2017Grant (prize money)$1.2M
• Mar 2017Grant (prize money)$300K
• Aug 2016Grant (prize money)$158K

Founders & team

Yie Hwa ChangFounder

Investors

HHS

Tech stack

Cart FunctionalityWordpressMysqlPhpBootstrapWoocommerce

Developer of biotherapeutics for the treatment of multiple diseases. It has discovered an oral pathogen that is the key to the pathogenesis of Alzheimer’s and cardiovascular disease. The company's lead candidate is KB-001 to treat inflammation-related diseases such as ischemic heart disease, stroke, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease (NAFLD), and autoimmune and neurodegenerative conditions.

Funding rounds

• Apr 2019Series A$5M

Founders & team

Garth EhrlichCo-FounderDaniel SindelarCo-Founder & CEO

Biotechnology company developing RNA production technology. It is a company that specializes in developing cost-effective RNA production for topical RNAi products used in biopesticides and other agricultural applications. It technology leverages a proprietary RNA manufacturing platform to produce double-stranded RNA for plant-based RNA interference solutions.

Funding rounds

• Apr 2018Seed$800K
• Jun 2017Seed—
• May 2017Conventional Debt$463.5K
• Apr 2015Seed$100K

Founders & team

Juan ArhancetFounderJohn KillmerCEO

Investors

Missouri Technology, BioGenerator, The Yield Lab, Helix Investments, Cultivation Capital

Developer of probiotic technology platform for diverse products and biochemicals. The company identifies, develops, and commercializes biological solutions. It focuses on creating safe and sustainable alternatives. The platform supports a portfolio of probiotic-powered products.

Provider of comprehensive genomics services for industrial research groups and institutions. The company offers the following services Sequencing, next-generation sequencing, array and assay development, immune assays, genotyping services, real-time PCR. It is a CLIA certified genomics company.