Best Healthcare IT Companies in Irvine, United States
The 66 best Healthcare IT companies in Irvine, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Masimo.
Our analysis of 90 Healthcare IT companies
$11.7b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Healthcare IT companies in Irvine
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Masimo Provider of wide range of devices to monitor health parameters | $151M | 46 mo ago | 2,200 2,200 → 3,672 (+67%) | 1989 | Joe Kiani Founder | Apple iCloud MailVimeoYouTube+19 | 2,303 patents Non‑invasive multi‑parameter patient monitoring, especially pulse oximetry and signal processing | 2 launchs · 1 expansion |
| 2 | Kareo Developer of software for clinical documentation billing and patient management | $146M | 93 mo ago | 313 | 2004 | Dan Rodrigues Co-Founder & CEO | Apple iCloud MailGoogle WorkspaceMUI+16 | — | — |
| 3 | LifeMasters Supported SelfCare Health improvement and chronic disease management programs and services | $59M | 219 mo ago | 143 | 1994 | — | — | 3 patents Personalized health risk assessment and patient management recommendation software | — |
| 4 | Movn Health Provider of care planning and coordination tool | $30M | 47 mo ago | 62 | 2013 | Shuo Qiao Co-Founder & CTO | WebflowApple iCloud MailGoogle Workspace+16 | — | — |
| 5 | Viseon Provider of digital visualization solutions for surgeons | $29M | 24 mo ago | 24 | 2017 | Alex Thomson Co-Founder | — | 37 patents Integrated camera-retractor systems and image overlay for enhanced intra‑operative visualization | 2 launchs |
| 6 | Path Central Web-based LIS for Pathologists | $15M | 162 mo ago | 26 | 2009 | — | — | — | — |
| 7 | Docbot AI-based disease diagnosis tool for decision making | $8M | 61 mo ago | 5 | 2013 | — | — | 15 patents Patents concentrated in health & consumer products | — |
| 8 | CuraPatient AI based platform offering claims management solutions | $8M | 46 mo ago | 10 | 2014 | Charles Rockefeller Co-Founder | — | — | — |
| 9 | TadHealth Comprehensive electronic health record platform for students and staff | $8M | 15 mo ago | — | 2021 | Ben Greiner Founder & Chief Executive Officer | — | — | — |
| 10 | Tagnos Healthcare workflow orchestration software optimizing hospital operations and patient care | $6M | 73 mo ago | 29 | 2010 | Neeraj Bhavani Founder & Board Member | — | 13 patents Patents concentrated in computing, sensing & instrumentation | — |
| 11 | Accenx Clinical lab providing PCR testing, research tools, and integration solutions | $4M | 207 mo ago | — | 1997 | David Cheng Founder | — | — | — |
| 12 | Branchpoint Technologies Medical devices for neuromonitoring and neurocritical care | $4M | 85 mo ago | — | 2011 | Nicholas Hu CEO | — | 7 patents Wireless intracranial pressure monitoring devices and systems for real-time brain health tracking | — |
| 13 | Virtual Dental Care Provider of software for tele dentistry | $3M | 75 mo ago | 25 | 2016 | Richard Lee CEO | — | — | — |
| 14 | MolecularWare Develops data management software | $2M | 298 mo ago | — | 1998 | Richard Ki ex-CEO | — | — | — |
| 15 | Allevion Therapeutics Developer of smart wearable for the treatment of essential tremors and other movement-related disorders | $1M | 27 mo ago | 3 | 2017 | — | — | — | — |
| 16 | Vena Vitals Provider of wearable sticker for monitoring blood pressure | $1M | 34 mo ago | 10 | 2019 | Michelle Khine Co-Founder | — | 6 patents Wearable multi‑channel sensor arrays for real‑time physiological signal monitoring | — |
| 17 | ClearPoint Neuro Developer of MRI-guided stereotactic system for neurological interventions | $1M | 13 mo ago | 38 | 1998 | Joe Burnett President and CEO | WordPressMySQLPHP+27 | 97 patents Minimally invasive neurosurgical targeting, delivery tools, and controlled infusion systems | 1 launch · 1 partnership |
| 18 | ACS Diagnostics Provider of ECG monitoring device | $300K | 146 mo ago | 37 | 1981 | — | WordPressMySQLPHP+37 | — | — |
| 19 | Planet DDS Dental practice management software solution in the cloud | $200K | 82 mo ago | 10 | 2003 | — | WordPress Block EditorWordPressMySQL+37 | — | 2 launchs |
| 20 | CenSyn Provider of EEG for rapid screening of non-convulsive seizures in neuro-ICU patients | $105K | 56 mo ago | 15 | 2019 | Ayushi Patel CEO | — | 12 patents Wearable EEG monitoring and fast indoor positioning/navigation technologies for medical applications | — |
Top 12 Healthcare IT companies in Irvine
#1
Public · Irvine, California · founded 2021$8Mraised▾
Comprehensive electronic health record platform for students and staff. It provides a comprehensive mental health platform specifically for educational institutions, including K-12 schools, to streamline behavioral health services and reduce barriers to care. The platform offers a purpose-built electronic health record system and supports healthcare.
- Feb 2025Series A$7.9M
- Oct 2021Seed$125K
#2
Public · Irvine, California · founded 1998 · 38 employees$1.3Mraised▾
Developer of MRI-guided stereotactic system for neurological interventions. It specializes in precise navigation systems for brain and spine procedures, enabling device, cell, and gene therapies with real-time imaging and minimally invasive techniques.
- May 2025Post IPO—
- Dec 2020Post IPO$7.5M
- May 2017Post IPO$13.2M
- Dec 2015Series B$5.3M
#3
Series B · Irvine, California · founded 2017 · 24 employees$29.4Mraised▾
Provider of digital visualization solutions for surgeons. It offers MaxView 4K Video Imaging Platform that offers visualization for minimally invasive spine surgery, MaxView Posterior for minimally invasive surgery of posterior spine, and MaxView 4K Imager for video recording, and routing signals.
- Jun 2024Series B—
- Feb 2020Series B$29.4M
#4
Acquired · Irvine, California · founded 1989 · 2200 employees$151.2Mraised▾
Provider of wide range of devices to monitor health parameters. The company offers a wide range of products across various categories include wearables Masimo W1 that provides untethered continuous pulse oximetry with visual and haptic notifications, Masimo W1 sport to track hydration levels, wireless earbuds with Masimo Adaptive Acoustic Technology for personalized sound, and Baby Monitoring Masimo Stork that tracks temperature, pulse rate, and oxygen saturation.
- Aug 2022Post IPO—
- Dec 2018Conventional Debt$150M
- Aug 2016Grant (prize money)$1.2M
#5
Series E · Irvine, California · founded 2004 · 313 employees$146.3Mraised▾
Developer of software for clinical documentation billing and patient management. This platform integrates electronic health records with tools for scheduling appointments, processing insurance claims, and managing patient communications. The system automates administrative tasks such as clinical note generation, eligibility verification, and payment collection. It provides functionality for telehealth consultations, electronic prescriptions, and laboratory result tracking. The software supports various medical practices by centralizing operational workflows into a single interface to facilitate clinical and financial tasks.
- Sep 2018Series E$9.9M
- Aug 2015Grant (prize money)$242.5K
- Jul 2015Series E$55.4M
- Oct 2014Conventional Debt$15M
#6
Series A · Irvine, California · founded 2013 · 62 employees$30Mraised▾
Provider of care planning and coordination tool. The company has developed a platform where patients can connect with providers, and assist with workflow management. It features care coordination, enrollment management, patient engagement, and more.
- Jul 2022Series A$20M
- Apr 2021Series A$6M
- Apr 2019Series A—
- Feb 2017Seed—
#7
Seed · Irvine, California · founded 2017 · 3 employees$1.5Mraised▾
Developer of smart wearable for the treatment of essential tremors and other movement-related disorders. The device can be worn around the wrist or ankle for delivering multimodal stimulation with proprietary delivery algorithms to reduce tremors. Its device learns and adjusts the use of each stimulation modality to optimize patient response.
- Mar 2024Seed$1.5M
- May 2018Seed—
#8
Series A · Irvine, California · founded 2014 · 10 employees$8.2Mraised▾
AI based platform offering claims management solutions. It provides AI insights that help organizations understand payer behavior. It core functionalities streamline key processes such as medical claims processing, patient engagement, reduce administrative tasks and support scalable and secure operations.
#9
Acquired · Irvine, California · founded 1994 · 143 employees$59Mraised▾
LifeMasters Supported SelfCare is a company which provides health improvement programs and services, which includes health promotion and disease management programs. create health partnerships among individuals, their physicians and payors. Offers programs for individuals with chronic diseases and de-addiction. Serves health plans, employers/consultants, retirement systems, governmental agencies, physicians, and public/caregivers. Had received Full Accreditation by the National Committee for Quality Assurance (NCQA) for its disease management (DM) programs.
- Mar 2008Series B$15M
- 2007Series A$44M
#10
Seed · Irvine, California · founded 2019 · 10 employees$1.4Mraised▾
Provider of wearable sticker for monitoring blood pressure. The sticker contains soft stretchable sensors that measure continuous blood pressure and provides an understanding of cardiovascular health.
- Aug 2023Seed—
- Aug 2023Grant (prize money)$295.9K
- May 2022Grant (prize money)$842.8K
- Feb 2021Grant (prize money)$256K
#11
Series A · Irvine, California · founded 2013 · 5 employees$8.5Mraised▾
AI-based disease diagnosis tool for decision making. The company has developed software "UltivisionAI" that uses AI technology to detect abnormalities in clinical reports. The system has features for automated reporting, and data-driven analytics, clinical workflow, practice management, and more. It has the ability to detect GI tract diseases for patients.
- May 2021Series A$4M
- 2019Seed$150K
- May 2019Seed$2M
- Feb 2019Grant (prize money)$225K
#12
Acqui-Hired · Irvine, California · founded 2009 · 26 employees$14.9Mraised▾
Path Central is a technology company offering software solutions and services to pathologists. It offers a web-based Anatomic Pathology Laboratory Information System (LIS) that integrates aspects of a pathology practice's business, like ordering, laboratory workflow management and specimen tracking, transcription, diagnosis, reporting, billing and financial analysis. The company was acquired by XIFIN in August 2013.
- Nov 2012Series B$1.9M
- Aug 2011Series B$3M
- Nov 2010Series B$10M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Healthcare IT coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health in Irvine is moving
A read on the academic research around Digital Health in Irvine — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 80 papers.
- University of California, Irvine73
- Irvine University14
- UC Irvine Health3
- Irvine Valley College3
- University of California, Irvine Medical Center3
- Remote patient monitoring2
- Real-time computing2
- Health informatics2
- Health care2
- Wireless sensor network1
- Health informatics6
- Mental health6
- Health care6
- Psychological intervention5
- mHealth4
- Mental health10
- Health care9
- Psychological intervention9
- Health informatics7
- Public health4
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.