Best Healthcare IT Companies in Minnesota, United States
The 159 best Healthcare IT companies in Minnesota, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Saluda Medical.
Our analysis of 90 Healthcare IT companies
$11.7b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Healthcare IT companies in Minnesota
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Saluda Medical Developer of neuromodulation platform measuring biomarkers for chronic neurological condition treatment 62Funding top 14%Moat top 31%News top 39%Growth top 42% All 8 signals ▾Fundingtop 14% Moattop 31% Newstop 39% Growthtop 42% Markettop 44% Techtop 45% Talentbottom 49% Globalbottom 43% Funding: Raised $400M across 8 rounds · 8 rounds over 14 yrs (0.6/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 62/100 | $400M | 7 mo ago | 327 | 2010 | Jim Schuermann CEO | — | 1 launch |
| 2 | WuXi Diagnostics Provider of solution for diagnosis of disease for healthcare providers | $200M | 63 mo ago | — | 2018 | Jason Liu CEO | — | — |
| 3 | vRad Provider of an AI-based software solution for radiology image analysis and teleradiology services | $70M | 192 mo ago | 353 353 → 546 (+55%) | 2001 | Gerry Fitterer Chief Executive Officer | — | — |
| 4 | Inbound Health Provider of a platform for hospital-at-home and skilled nursing-at-home programs | $50M | 33 mo ago | 48 | 2022 | Dave Kerwar Co-Founder and Chief Executive Officer | — | — |
| 5 | Immune IQ Provider of a point-of-care diagnostic platform for immune diseases | $36M | 52 mo ago | 42 | 2008 | — | 491 patents Tau protein-based therapeutics and vaccines for neurodegenerative disease treatment | — |
| 6 | Omcare Remote monitoring and medication adherence solutions for healthcare professionals | $25M | 23 mo ago | 20 | 2011 | Lisa Lavin Founder & CEO | 5 patents Smart web‑connected medication dispensers with audiovisual feedback and compliance verification | 1 award |
| 7 | Carrot Health Cloud-based healthcare business & marketing intelligence solutions | $25M | 91 mo ago | 43 | 2014 | — | — | — |
| 8 | Astrin AI-empowered 3D holographic imaging platform for early cancer detection | $23M | 24 mo ago | 19 19 → 26 (+37%) | 2021 | Jayant Parthasarathy Chief Executive Officer | — | 1 launch |
| 9 | Mednet Cloud-based platform provider for e-clinics and electronic data | $20M | 114 mo ago | 55 55 → 92 (+67%) | 2012 | Rob Robertson President/CEO | 2 patents Medical imaging data acquisition and clinical trial site management software solutions | 2 partnerships |
| 10 | Revel Provider of a platform for the management of care plans | $17M | 102 mo ago | 106 | 2006 | — | — | — |
| 11 | Kyros Provider of suite solutions for patients, providers, and organizations | $17M | 33 mo ago | 42 | 2021 | — | — | — |
| 12 | Reema Provider of integrated behavioral health and social care services | $17M | 6 mo ago | 42 | 2019 | Matt Swanson Co-Founder | — | — |
| 13 | HealtheMed Provider of integrated digital system solution services | $15M | 24 mo ago | 23 | 2018 | Thomas Spencer Co-Founder & CEO | — | — |
| 14 | ProVation Medical Clinical documentation and workflow automation solutions improving healthcare quality | $14M | 289 mo ago | 184 184 → 352 (+91%) | 1994 | — | — | — |
| 15 | Sansoro Health Provides EMR interoperability through universal application programming interfaces (APIs) | $14M | 94 mo ago | 21 | 2014 | — | — | — |
| 16 | GEM Health Provider of treatment solutions for sleep apnea 37Tech top 30%Growth top 35%Funding top 39%Talent bottom 49% All 6 signals ▾Techtop 30% Growthtop 35% Fundingtop 39% Talentbottom 49% Globalbottom 32% Marketbottom 19% Tech: 29 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 37/100 | $13M | 20 mo ago | 8 | 2020 | Brian Sauer Founder & CEO | — | 1 job opening |
| 17 | NeuroOne Developer of AI-enabled diagnostic and treatment devices for neurological diseases | $13M | 65 mo ago | 15 | 2017 | — | 5 patents Implantable neural depth probes for brain recording and localized drug delivery | — |
| 18 | Ambient Clinical Clinical analytics solutions improving patient outcomes and healthcare efficiency through data visualization | $10M | 6 mo ago | 12 | 2014 | — | — | — |
| 19 | mPay Gateway Online access and printing for W-2 and 1095-C tax forms | $10M | 165 mo ago | 6 | 2004 | McGuire Patrick Co-Founder | 3 patents Healthcare financial transaction processing with delayed settlement mechanisms | — |
| 20 | Jump Technologies Supply chain management solutions for the healthcare industry | $10M | 49 mo ago | 6 | 2012 | — | 2 patents Digital media logging systems and optimized additive barcode encoding for business catalogs | — |
| 21 | Chart Talk Practice management software with customizable voice dictation ability | $8M | 111 mo ago | — | 2015 | Judy Barnes CEO | — | — |
| 22 | SecondWave Systems Digital medical imaging solution for healthcare professionals | $7M | 7 mo ago | 7 | 2019 | — | — | 1 job opening |
| 23 | SynerFuse Provider of pain management platform for healthcare professionals | $7M | 59 mo ago | 5 | 2015 | Justin Zenanko Co-Founder | 77 patents Spinal neuromodulation device implantation, lead anchoring, and robotic surgical navigation. | 1 launch |
| 24 | OptimizeRx Cloud-based digital communication platform for hospital point of care management | $6M | 90 mo ago | 94 94 → 133 (+41%) | 2006 | William Febbo CEO | 5 patents Digital health marketing and real-time provider communication platforms for medication promotion. | — |
| 25 | LogicStream AI-powered pharmacy solutions for optimized operations, cost savings, and improved outcomes | $6M | 109 mo ago | 36 | 2013 | — | — | — |
| 26 | Vios Medical Remote patient monitoring system for healthcare providers | $6M | 134 mo ago | 35 | 2012 | — | — | — |
| 27 | Orasi Medical Provider of imaging software to diagnose and monitor neurological diseases | $5M | 187 mo ago | — | 2007 | Mark T. Wagner CEO | — | — |
| 28 | The Wound Company Provider of virtual wound care platform for patients and providers | $4M | 36 mo ago | 25 | 2022 | Sanford Roberts Co-Founder | — | — |
| 29 | ApeniMED Cloud based Health Information Exchange platform | $4M | 177 mo ago | 50 | 2007 | John Fraser Ex- CEO | — | — |
| 30 | NightWare Developer of a prescription digital therapeutic system for nightmare disorder 32Patents top 45%Innovation top 47%Funding top 47%Growth bottom 49% All 9 signals ▾Patentstop 45% Innovationtop 47% Fundingtop 47% Growthbottom 49% Talentbottom 49% Techbottom 45% Fin. healthbottom 45% Globalbottom 44% Marketbottom 28% Patents: 8 patents matched (strict assignee match) · 6 filings since 2022 vs 2 in 2017-21 Innovation: 8 patents (top 73% of patent-holders) · 6 filings since 2022 vs 2 in 2017-21 rank vs industry peers · Fliar Intelligence Index 32/100 | $4M | 3 mo ago | 16 | 2015 | Matthew Tucker Chief Executive Officer | 8 patents Wearable-based stress and nightmare detection with automated therapeutic interventions for sleep health | — |
| 31 | Indigo Identityware Secure identity management solutions | $3M | 162 mo ago | — | 2009 | Thomas Rheineck President & CEO | 7 patents Secure messaging protocols and password‑free authentication/graphical ID systems | — |
| 32 | Smart Data Solutions Platform for healthcare workflow automation | $3M | 176 mo ago | 180 | 2001 | — | — | 1 launch · 1 expansion |
| 33 | Medicom Health Interactive Risk management solution for individuals and health care providers | $3M | 103 mo ago | 5 | 2000 | — | — | — |
| 34 | Luminat Tools to collect patient generated health information | $3M | 138 mo ago | — | 2012 | Tom Valdivia Co-Founder & CEO | — | — |
| 35 | Inspired Life Medical Developer of screening tools for Alzheimer's disease | $3M | 70 mo ago | — | 2018 | David Wagner Founder & CEO | — | — |
| 36 | Champaign Imaging Advancing quieter, motion-corrected MRI neuroimaging for "hard-to-image" patients | $3M | 46 mo ago | — | 2015 | Curt Corum Co-Founder & President & CEO | — | — |
| 37 | Nested Knowledge Provider of a clinical evidence platform for pharma, device, and research entities | $3M | 5 mo ago | 9 | 2018 | Stephen Mead Co-Founder | 5 patents Automated systematic review platforms with ontology-driven data analysis and visualization | 1 launch · 3 partnerships |
| 38 | Surgical Information Sciences AI and cloud-based platform for visualizing brain MRI images | $3M | 79 mo ago | — | 2012 | Guillermo Sapiro Co-Founder | — | — |
| 39 | Phrazer Enhancing patient and staff engagements with equitable, integrated healthcare solutions | $2M | 182 mo ago | — | 2007 | Mat Johnson Founder & CEO | — | — |
| 40 | Clinician Nexus Provider of clinical education management software | $2M | 78 mo ago | 7 | 2016 | Bob Bryan Co-Founder | — | — |
| 41 | Juniper Health Digital practice management tool for providers | $2M | 53 mo ago | — | 2019 | Steve Claypool Co-Founder | — | — |
| 42 | Imbio AI-powered medical imaging analysis for personalized lung and cardiothoracic care | $2M | 45 mo ago | 15 | 2005 | — | 3 patents AI-driven medical image analysis and automated diagnostic reporting | — |
| 43 | Boundary Medical Clinical outcomes analytics for healthcare organizations | $1M | 205 mo ago | 1 | 2001 | John Bullion CEO | — | — |
| 44 | Geneticure Personalized hypertension treatment through DNA analysis for better medication selection | $1M | 110 mo ago | 9 | 2012 | — | 19 patents Genetic diagnostics and therapeutics for hypertension and coronavirus infections | — |
| 45 | Hinckley Medical Provider of gurney scale and protocol app for EMS professionals | $1M | 8 mo ago | 8 | 2020 | Michael Elsbernd Co-Founder | — | 1 launch · 1 partnership |
| 46 | Hitch Health Innovative software connecting patients to transportation, reducing no-show rates | $900K | 95 mo ago | — | 2017 | Chip Truwit Co-Founder & CEO | — | — |
| 47 | SuraMedical Provider of a wearable device for chronic wound care | $299K | 57 mo ago | 4 | 2016 | Jonathan Engel Co-Founder and Chief Technology Officer | 2 patents Wearable sensor systems for chronic lower‑extremity wound monitoring and management | — |
| 48 | CoraVie Developer of FDA-approved patent-pending devices for the treatment of cardiac health | $295K | 46 mo ago | 2 | 2020 | — | — | — |
| 49 | Marrow Access Provider of a smart medical device for marrow stimulation therapy | $241K | 3 mo ago | 6 | 2017 | — | — | 1 launch |
| 50 | TripFlow Developer of software for non-emergency medical transportation management and optimization | $115K | 14 mo ago | — | 2025 | Timothy Visser Founder & CEO | — | — |
Top 12 Healthcare IT companies in Minnesota
#1
Public · Bloomington, Minnesota · founded 2010 · 327 employees$400Mraised▾
Developer of neuromodulation platform measuring biomarkers for chronic neurological condition treatment. It offers a system that measures and records neural activation characteristics. The system quantifies stimulation levels to a clinician-defined target, continuously comparing neural activation with the target level. It automatically adjusts stimulation current to ensure consistent neural activation. The company focuses on neuromodulation solutions for chronic pain. It utilizes Evoked Compound Action Potentials to advance neuromodulation therapy.
- Oct 2025Series F$30M
- Jan 2025Series F$100M
- Apr 2023Series F$150M
- Mar 2022Series F$125M
#2
Series B · Minneapolis, Minnesota · founded 2019 · 42 employees$16.9Mraised▾
Provider of integrated behavioral health and social care services. It addresses unmet social needs impacting members' mental and physical well-being. Services include one-on-one support from community care workers, virtual behavioral health care, and navigation assistance for various needs such as food insecurity, housing, and transportation. The approach focuses on personalized care plans and building relationships to overcome barriers to accessing care. This model aims to improve health outcomes and reduce healthcare costs.
- Dec 2025Series B$19M
- Jun 2025Series B$18.9M
- Oct 2024Series A$7.6M
- Mar 2022Seed$8M
#3
Series B · Rochester, Minnesota · founded 2014 · 12 employees$10.3Mraised▾
Clinical analytics solutions improving patient outcomes and healthcare efficiency through data visualization. They provide digital health and clinical decision support automation tools designed for various healthcare settings, including bedside care, nurse stations, clinical command centers, and remote monitoring. Their solutions are scientifically and clinically proven to lower costs, reduce errors, and save lives. They offer a suite of AWARE products, including Sepsis DART, Patient Surveillance, Clinical Control Tower, Certain, and YES Board, addressing critical conditions like sepsis and optimizing patient flow management. The company leverages healthcare data visualization, predictive analytics, and a Clinical Mesh Network to enhance provider efficiency, situational awareness, and telehealth capabilities. They are FDA Class II cleared, CE Marked, and ISO certified, demonstrating a commitment to quality and regulatory compliance. This is a B2B, SaaS, software company.
- Dec 2025Series B$5M
- Jan 2021Series A$300K
- Apr 2020Series A$525K
- Jun 2019Series A$600K
#4
Seed · Hopkins, Minnesota · founded 2015 · 16 employees$3.5Mraised▾
Developer of a prescription digital therapeutic system for nightmare disorder. This system is designed to reduce sleep disturbances related to nightmare disorder or nightmares stemming from PTSD. It uses intuitive Apple products and tailors therapy to individual sleep patterns. The system is FDA-cleared and offers a low-risk treatment option with no known drug interactions. It aims to improve sleep quality within two weeks and can be used alongside other treatments. The system's safety and efficacy are supported by clinical trial data.
- Feb 2026Seed$250K
- Aug 2025Seed$1.1M
- Jul 2022Seed$700K
- Aug 2021Seed$1M
#5
Series A · Saint Paul, Minnesota · founded 2018 · 9 employees$2.6Mraised▾
Provider of a clinical evidence platform for pharma, device, and research entities. The company offers a digital platform that helps both clinicians and corporate researchers to optimize their meta-analytical research process in a modernized visualization tool for comparing patient characteristics, treatment plans, and therapy outcomes. They offer individual and institutional subscriptions to use the platform to build and present 'living' reviews as well as employing proprietary AI technologies to enhance the research process.
- Dec 2025Series A$4.2M
- Sep 2024Grant (prize money)$305K
- Dec 2023Seed$1M
- Feb 2023Seed$25K
#6
Series A · Minneapolis, Minnesota · founded 2019 · 7 employees$7Mraised▾
Digital medical imaging solution for healthcare professionals
- Oct 2025Series A—
- Apr 2025Series A$7M
#7
Series B · Burnsville, Minnesota · founded 2011 · 20 employees$25.5Mraised▾
Remote monitoring and medication adherence solutions for healthcare professionals. The company offers a telecommunication platform that enables caregivers to contact patients and track their medication and health.
- Jun 2024Series B$2.8M
- Mar 2024Series B$8.2M
- Mar 2023Series A$5.3M
- Mar 2022Series A$3.2M
#8
Seed · Eden Prairie, Minnesota · founded 2017 · 6 employees$241.4Kraised▾
Provider of a smart medical device for marrow stimulation therapy. The company offer SmartShot device that provide access to stem cell-rich marrow with less bone disruption than traditional microfracture methods.
- Mar 2026Conventional Debt—
- Mar 2026Seed$100K
- Mar 2024Seed$241.4K
#9
Seed · Lakeville, Minnesota · founded 2020 · 8 employees$1.1Mraised▾
Provider of gurney scale and protocol app for EMS professionals. It offers OneDose app, an interactive protocol workflow app, and OneWeight, the first patient scale attachment for ambulance gurneys for patient care by ensuring accurate weight-based dosing and streamlined protocol adherence.
- Sep 2025Seed$2.7M
- Dec 2023Seed$1.1M
#10
Series A · Minneapolis, Minnesota · founded 2020 · 8 employees$13Mraised▾
Provider of treatment solutions for sleep apnea. The company offers a digital therapeutic tool for users to help with sleep apnea. It provides sleep coaching provides, appointment booking with sleep specialists, prescribed medications, and online support for prevention, diagnosis, and treatment for sleep apnea.
- Oct 2024Series A$7M
- Sep 2023Seed—
- May 2023Seed$3M
- Mar 2022Seed$3M
#11
Series B · Saint Paul, Minnesota · founded 2021 · 19 employees$22.9Mraised▾
AI-empowered 3D holographic imaging platform for early cancer detection. The company utilizes Deep Learning and 3D Holographic Imaging to analyze individual cells using current non-cell-based approaches for the detection of cancer.
- May 2024Series B$22.9M
- Jun 2022Grant (prize money)$399.7K
#12
Series A · St. Louis Park, Minnesota · founded 2018 · 23 employees$15.4Mraised▾
Provider of integrated digital system solution services
- May 2024Series A$7M
- Jan 2023Seed$5.7M
- Aug 2022Seed$1.5M
- Apr 2022Seed$1.2M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Healthcare IT coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health in Minnesota is moving
A read on the academic research around Digital Health in Minnesota — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 77 papers.
University of Minnesota and Minnesota Department of Health lead Minnesota's digital-health research, focusing on EHR systems and health policy implementation, with a cautiously optimistic yet concern-weighted tone.
- University of Minnesota57
- Minnesota Department of Health11
- University of Minnesota Medical Center7
- University of Minnesota System7
- Minnesota Project4
- Health informatics2
- Somali1
- Health communication1
- Health psychology1
- Dissemination1
- Health informatics11
- Health care6
- Informatics4
- Public health4
- Health administration4
- Health informatics2→10
- Public health1→6
- Health care3→6
- Informatics1→3
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.