Best High Tech Companies in Madison, United States
The 50 best High Tech companies in Madison, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Propeller Health.
Our analysis of 306 High Tech companies
$95.7b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best High Tech companies in Madison
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Propeller Health Mobile platform and a sensor for respiratory health management | $64M | 98 mo ago | Acquired | 119 | — | Apple iCloud MailSalesforce DeskSalesforce+7 | — | — |
| 2 | Understory Provider of ground-based dot sensors to collect hyperlocal weather data | $58M | 32 mo ago | Series B | 20 | Adam Dershewitz Co-Founder & CTO | — | 50 patents IoT weather sensors and data processing for environmental and multimedia applications | — |
| 3 | Perceptive IO AI-powered automated robotic surgery device for dentists | $45M | 11 mo ago | Series B | — | Chris Ciriello Co-Founder & CEO | Craft CMSPHPYii+9 | 22 patents Vehicle safety and autonomous perception sensors integrating IR seat‑belt detection and centralized object detection networks. | — |
| 4 | Imbed Biosciences Provider of nanotech-based wound care products 48Growth top 32%Funding top 37%Talent top 38%Moat top 39% All 7 signals ▾Growthtop 32% Fundingtop 37% Talenttop 38% Moattop 39% Techtop 44% Marketbottom 33% Globalbottom 32% Growth: Headcount 24 → 35 (+46%) across vintages · Fresh capital in last 24 mo Funding: Raised $34.3M across 18 rounds · 18 rounds over 16 yrs (1.1/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $34M | 6 mo ago | Series C | 35 35 → 40 (+14%) | Michael Schurr Co-Founder & Chief Medical Officer | WordPress Block EditorCart FunctionalityWordPress+30 | — | — |
| 5 | Tascet Cybersecurity solutions provider specializing in fraud prevention and quantum infrastructure security | $13M | 168 mo ago | Series A | 11 | — | — | — | — |
| 6 | Allergy Amulet Developer of a portable food allergen sensor for sample detection 42Moat top 31%Tech top 33%Growth top 35%Funding top 40% All 10 signals ▾Moattop 31% Techtop 33% Growthtop 35% Fundingtop 40% Producttop 46% Talentbottom 49% Innovationbottom 47% Patentsbottom 35% Globalbottom 31% Marketbottom 27% Moat: Editorial + unicorn rating 7/10 · IP moat: 11 patents Tech: 38 technologies across 4/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 42/100 | $13M | 23 mo ago | Series A | 18 | Joseph BelBruno Co-Founder | Squarespace CommerceSquarespaceProton Mail+30 | 11 patents Electrochemical sensors for detecting food allergens via electropolymerized detection layers. | — |
| 7 | Mirus Bio Developer of transfection reagents and electroporation products | $7M | 215 mo ago | Acquired | 33 33 → 63 (+91%) | — | WordPressSalesforceSalesforce Service Cloud+30 | — | — |
| 8 | Medical Cyberworlds AI-powered VR training for emotional intelligence and communication skills | $5M | 58 mo ago | Seed | 3 | Fred Kron Founder & CEO | — | — | — |
| 9 | TrafficCast Large scale traffic data analytics for navigation | $4M | 222 mo ago | Acquired | 39 | — | — | 7 patents Real-time traffic data collection, analysis, and management network systems for road transportation. | — |
| 10 | Ebullient Offers cooling systems for data centers | $3M | 114 mo ago | Series A | 9 | — | — | 69 patents Advanced two-phase cooling heat sink modules for high‑power electronics thermal management. | — |
| 11 | Atrility Medical AI-powered cardiac monitoring for clearer decisions and improved patient care 24Innovation top 40%Funding top 43%AI top 45%Talent top 45% All 8 signals ▾Innovationtop 40% Fundingtop 43% AItop 45% Talenttop 45% Producttop 46% Techbottom 30% Globalbottom 29% Marketbottom 15% Innovation: 2 product lines Funding: Raised $3.4M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 24/100 | $3M | 9 mo ago | Series A | 8 | Nick Bergen Co-Founder | — | — | — |
| 12 | Dianomi Therapeutics Developer of therapies for treating inflammatory diseases | $3M | 71 mo ago | Series A | 7 | — | — | — | — |
| 13 | StitchKit Provider of healthcare kit for robotic surgery | $2M | 75 mo ago | Seed | — | Patrick Culligan Founder & CEO | — | — | — |
| 14 | Wi2Wi Provider of a location tracking platform 32Product top 14%Funding top 39%Moat top 45%Growth top 48% All 10 signals ▾Producttop 14% Fundingtop 39% Moattop 45% Growthtop 48% Globalbottom 49% Talentbottom 49% Innovationbottom 45% Marketbottom 40% Patentsbottom 29% Techbottom 23% Product: 9 distinct product lines · Company stage: Public Funding: Raised $2.2M across 4 rounds · 4 rounds over 2 yrs (2.0/yr) rank vs industry peers · Fliar Intelligence Index 32/100 | $2M | 12 mo ago | Public | 45 45 → 27 (-40%) | Zachariah J Mathews CEO & President | JoomlaPHPBootstrap+7 | 3 patents Integrated circuit package reliability: ESD protection, built‑in self‑test and self‑repair. | — |
| 15 | Fishidy Geo-map based social community platform for fishers | $2M | 146 mo ago | Series A | 3 | Brian Jensen Founder & CEO | TypeScriptMapbox GL JSZone.js+10 | — | — |
| 16 | Origami Surgical Developer of robotic-assisted surgery devices for surgeons | $1M | 12 mo ago | Seed | 5 | Patrick Culligan Founder / CMO | — | — | — |
| 17 | mdotLabs Advertising security platform | $1M | 152 mo ago | Acqui-Hired | 14 | Timur Yarnall Co-Founder & CEO | — | — | — |
| 18 | Co-drx Developer of nanoparticle chemotherapy drugs for cancer | $428K | 92 mo ago | Seed | 4 | — | — | — | — |
| 19 | InStepNanoPower Wearable solution that can convert mechanical energy into electrical energy | $298K | 193 mo ago | Funding Raised | — | Tom Krupenkin President & CEO | — | — | — |
| 20 | SimplifIDe Security solution for secure authentication to enhance customer experience | $285K | 113 mo ago | Deadpooled | 5 | Nick Fuhrman Co-Founder & CMO | — | — | — |
| 21 | Holos VR learning platform enabling experts to create immersive educational experiences | $200K | 78 mo ago | Seed | 8 | Tyler Waite Co-Founder / COO & CCO | — | — | — |
| 22 | Linectra Metal 3D Printer manufacturer | $150K | 53 mo ago | Seed | 2 | Brandon Walker CEO and Co-Founder | — | — | — |
| 23 | FANTM Developer of AI-based and wearable neuro-computer interfaces for gesture sensing | $100K | 74 mo ago | Seed | 2 | — | — | — | — |
| 24 | Dock Technologies Provider of wearable devices for remote patient monitoring | $100K | 140 mo ago | Seed | 1 | Sarah Sandock Founder & CEO | — | 103 patents Marine dock boarding and launch hardware for small watercraft and swimmers. | — |
Top 12 High Tech companies in Madison
#1
Series C · Madison, Wisconsin · founded 2010 · 35 employees$34.3Mraised▾
Provider of nanotech-based wound care products. The company has developed technologies for embedding bioactive molecules in wound dressings and surgical implants. The products are based on the Microlyte Matrix technology platform. The company also offers antibacterial, anti-biofilm, and analgesic wound dressings.
- Jan 2026Series C—
- Jan 2024Convertible Debt$10M
- Dec 2023Series B$3.5M
- May 2023Series B$2.5M
#2
Series B · Madison, Wisconsin · founded 2018$45.1Mraised▾
AI-powered automated robotic surgery device for dentists. The company combines novel imaging technology with AI and surgical robotics to automate surgery in dental industry.
- Aug 2025Grant (prize money)$1.7M
- Jul 2025Series B—
- Jul 2024Series B$30M
- Sep 2023Grant (prize money)$1.7M
#3
Series A · Madison, Wisconsin · founded 2017 · 8 employees$3.4Mraised▾
AI-powered cardiac monitoring for clearer decisions and improved patient care. This company is focused on transforming bedside monitoring through its innovative AtriRhythm AI platform and AtriAmp device. They provide solutions for critical care arrhythmia monitoring, addressing challenges in post-operative settings. Their technology facilitates continuous atrial electrogram monitoring, aiding in the diagnosis and treatment of atrial arrhythmias. The AI platform offers real-time component recognition, retrospective signal labeling, and literature-based interval mapping, providing clinicians with verifiable clinical insights. They are dedicated to improving cardiac health and patient outcomes through advances in medical technology, integrating healthcare, business, and engineering expertise. Their focus is on cardiac medical devices, atrial electrogram, arrhythmia monitoring, AI, and patient care.
- Nov 2025Series A$1M
- Sep 2024Grant (prize money)$275K
- Jun 2022Series A$3.4M
- Sep 2020Conventional Debt$300K
#4
Public · Madison, Wisconsin · founded 2005 · 45 employees$2.2Mraised▾
Provider of a location tracking platform. Its products include wireless connectivity solutions, such as Wi-Fi/Bluetooth/Bluetooth Low Energy, location and navigation products including GNSS and GPS modules; timing and frequency control products such as clock oscillators, crystals, crystal filters, and RF and microwave filters. Applications are in the areas of avionics, space, military, defence, government, infrastructure, industrial, automotive, medical, communications etc. Technology partners include ASE group, STMicroelectronics, and IAR Systems.
- Jul 2025Post IPO$510.8K
- Feb 2025Post IPO$667.4K
- Dec 2024Post IPO$417.4K
- Nov 2024Post IPO$600K
#5
Series A · Madison, Wisconsin · founded 2016 · 18 employees$12.6Mraised▾
Developer of a portable food allergen sensor for sample detection. The device allows users to test food samples for the presence of allergenic ingredients. It is designed to detect allergens at levels that could trigger reactions. The sensor pairs with an application to track results.
- Aug 2024Series A$5.8M
- Jan 2022Grant (prize money)—
- Mar 2021Seed$800K
- Aug 2020Seed$3.3M
#6
Seed · Madison, New Jersey · founded 2010 · 5 employees$1.4Mraised▾
Developer of robotic-assisted surgery devices for surgeons. The company has developed a patented portfolio StitchKit product that is a single-use canister designed to pass multiple strands of the suture with attached needles into the surgery site. It provides StitchKit PTFE that contains six strands of PTFE and the device is designed with input from leading gynecologic surgeons to facilitate robotic-assisted Sacrocolpopexy. It also offers StitchKit PARK that enables the surgeon to customize the contents of the StitchKit device.
- Jul 2025Seed$450K
- Sep 2024Seed$1.5M
- Dec 2023Seed$1.4M
#7
Series B · Madison, Wisconsin · founded 2012 · 20 employees$57.8Mraised▾
Provider of ground-based dot sensors to collect hyperlocal weather data. The hardware offering detects rain, hail, winds, and other weather events at the surface of the earth. The information collected by the device is analyzed and processed to create real-time datasets and views of the movement and intensity of weather events to provide insight and early detection of risks. The sensors are solar-powered and can detect three-dimensional rain, hail, wind, and other weather at the ground level. It also offers parametric hail insurance for auto dealerships.
- Nov 2023Series B$15M
- Jun 2023Series B$13.1M
- Apr 2021Series B$5.5M
- May 2019Series B$7.2M
#8
Acquired · Madison, Wisconsin · founded 2010 · 119 employees$64Mraised▾
Mobile platform and a sensor for respiratory health management. It provides a data-collecting sensor that can be put onto one end of a medication inhaler. The sensor records when and where a patient has used inhaled medications. Provides patients with a continuous, objective assessment of their disease along with personalized guidance and targeted education to help them improve. Personalized messages are sent to patients through Propeller’s online page, e-mails, and text messages to help them understand the patterns behind their daily symptoms and use of medications.
- May 2018Series C$20M
- Oct 2016Series C$21.5M
- Sep 2014Series B$14.5M
- Jun 2013Series A$1M
#9
Seed · Madison, Wisconsin · founded 2006 · 3 employees$5.3Mraised▾
AI-powered VR training for emotional intelligence and communication skills. They leverage Artificial Intelligence and Virtual Reality to provide immersive, emotionally charged simulated human interactions. Their MPathic-VR™ technology captures and analyzes learner behaviors, providing personalized feedback and reflection opportunities. This innovative approach addresses the complexities of emotional intelligence training, improving social awareness, emotional understanding, and behavioral regulation. The solution aims to enhance communication skills across various sectors, including healthcare, law enforcement, workplace environments, the military, law, and academia. It offers a transformative learning experience, fostering empathy, reducing bias, and promoting positive outcomes through practice and adaptation. This is a SaaS based solution.
- Sep 2021Grant (prize money)$2.4M
- Aug 2009Grant (prize money)$2.4M
- Aug 2009Grant (prize money)$464K
- Seed—
#10
Series A · Madison, Wisconsin · founded 2005 · 11 employees$13.2Mraised▾
Cybersecurity solutions provider specializing in fraud prevention and quantum infrastructure security. They offer a security system that serves as the backbone of an organization's enterprise risk strategies, enforcing security protocols to protect borders and boundaries, secure critical assets, and prevent cyberattacks and fraud. Their Global Uniqueness Registry ensures users are unique, preventing synthetic identities and impersonation. They provide security credentials, not dependent on devices, controlled by the organization, eliminating risks like account takeover and phishing. They transform Zero Trust architectures into prevent-and-protect strategies, utilizing security credentials immune to compromise. They prevent fraud in payments and point-of-sale, stopping synthetics and imposters. They offer solutions for financial, healthcare, government, payments, telecom, travel, retail, education, and insurance industries. They provide a high-value security asset owned and controlled by the organization, bringing a profound change to its enterprise risk strategies.
- Aug 2012Series A$13.2M
#11
Acquired · Madison, Wisconsin · founded 1995 · 33 employees$6.8Mraised▾
Developer of transfection reagents and electroporation products. The company's products include TransIT-VirusTransfection Reagent and Kits, virus production, and transduction products. It also offers delivery systems for molecular and cell biology applications.
- Sep 2008Grant (prize money)$155.1K
- Aug 2007Grant (prize money)$5.4M
- Oct 2004Grant (prize money)$1.3M
#12
Series A · Madison, Wisconsin · founded 2017 · 7 employees$3Mraised▾
Dianomi Therapeutics is developing therapies for treating inflammatory diseases (osteoarthritis and pain). They have developed their proprietary platform, Mineral Coated Microparticle (MCM) technology for sustained release delivery and to improve efficacy and safety. It mimics the natural properties of mineralized tissues (bones and teeth). The platform has applications for a wide range of drugs including protein biologics and small molecules.
- Sep 2020Grant (prize money)$251.9K
- Feb 2019Series A$3M
- Jan 2019Conventional Debt$185K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of High Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Semiconductors in Madison is moving
A read on the academic research around Semiconductors in Madison — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 46 papers.
- University of Wisconsin–Madison42
- Madison Area Technical College5
- Optoelectronics3
- Amplifier2
- Electronic circuit2
- Hardware Trojan2
- Trojan2
- Semiconductor device4
- Optoelectronics4
- Transistor4
- Integrated circuit4
- Overhead (engineering)3
- Electronic circuit1
- CMOS1
- Power consumption1
- Image sensor1
- Electrical efficiency1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.