Best High Tech Companies in San Antonio, United States
The 41 best High Tech companies in San Antonio, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: PlusOne Robotics.
Our analysis of 306 High Tech companies
$95.7b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best High Tech companies in San Antonio
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | PlusOne Robotics Provider of AI-powered vision software for warehouse automation and robotics | $100M | 41 mo ago | 102 | Shaun Edwards Co-Founder & CTO | WebflowYouTubecore-js+16 | Top 50M | — | — |
| 2 | Xenex Provider of disinfection robots for multiple healthcare purposes | $94M | 90 mo ago | 79 | — | WordPressMySQLPHP+30 | Top 5M | — | — |
| 3 | WellAware Offering monitoring and management services for oil industry | $60M | 132 mo ago | 22 22 → 42 (+91%) | Matt Harrison Co-Founder and Board Member | WordPressMySQLPHP+32 | Top 50M | 64 patents Remote industrial IoT monitoring and control systems for oil and gas equipment safety | — |
| 4 | Darkhive Developer of drone-based defense solutions | $25M | 23 mo ago | 8 | John Goodson Co-Founder & CEO | — | — | 9 patents Modular drone launch/containment hardware and autonomous UAV operation technologies. | — |
| 5 | SecureLogix Cloud based platform offering secure communication solutions | $25M | 280 mo ago | 69 69 → 76 (+10%) | Lee Sutterfield CEO | SkolengoSentryNode.js+18 | Top 50M | 18 patents Real-time telephony authentication via biometric and cryptographic verification of call devices | 1 job opening · 2 partnerships |
| 6 | Merge Provider of an augmented and virtual reality based educational solution | $10M | 123 mo ago | 21 | — | Cart FunctionalityShopifyZURB Foundation+25 | Top 1M | 40 patents AR/VR collaborative streaming and real‑time communication using trackable 3‑D objects | — |
| 7 | Renu Robotics Provider of a solar panel management robot system | $7M | 56 mo ago | 68 | Tim Matus Founder & CEO | WordPressMySQLPHP+17 | Top 50M | 19 patents Autonomous ground‑vehicle operation, infrastructure setup, and terrain/obstacle sensing for maintenance | — |
| 8 | Parlevel Systems Provider of hardware and software solutions for hospitality industry | $6M | 114 mo ago | 57 | Alan Munson Co-Founder and CCO | WordPressMySQLPHP+22 | Top 10M | — | — |
| 9 | Azaya Therapeutics Developer of small molecule liposomal formulations for cancer therapy | $5M | 183 mo ago | 11 | — | — | — | — | — |
| 10 | Wytec International Provider of cellular network telecommunication services 7Funding top 49%Tech bottom 49%Talent bottom 45%Moat bottom 37% All 9 signals ▾Fundingtop 49% Techbottom 49% Talentbottom 45% Moatbottom 37% Globalbottom 29% Patentsbottom 27% Fin. healthbottom 19% Marketbottom 18% Innovationbottom 14% Funding: Raised $3.2M · 17 rounds over 14 yrs (1.2/yr) Tech: 33 technologies across 3/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 7/100 | $3M | 22 mo ago | 12 | William H. Gray CEO | WordPressZohoMySQL+30 | Top 50M | 4 patents High‑speed, upgradeable multichannel data transmission for telecommunications networks | — |
| 11 | WiseWear Developing Luxury Tech Jewelry. | $3M | 124 mo ago | 8 | — | — | — | 16 patents Wearable health monitoring with haptic messaging and integrated coplanar antenna technology. | — |
| 12 | Reckon Point Precise indoor positioning and navigation solution using Wi-Fi and geomagnetic signals | $2M | 82 mo ago | 7 | — | — | — | — | — |
| 13 | MR3Health Provider of monitoring services to health insurers for diabetic neuropathy patients | $1M | 49 mo ago | 10 | — | — | — | — | — |
| 14 | Soloshot Automatic robot cameraman for filming sports and activities | $1M | 131 mo ago | 10 | Christopher Boyle Founder & CEO | Cart FunctionalityShopifyFacebook Login+24 | Top 10M | — | — |
| 15 | Leaptran AI-powered forecasting solutions for grid resilience and operational foresight | $925K | 36 mo ago | 6,977 | Jeff Xu President/CEO | — | — | — | — |
| 16 | AVA Propulsion Developer of VTOL-capable autonomous aircraft | $500K | 106 mo ago | 3 | David Gonzales CEO | — | — | — | — |
| 17 | Pomika Provider of a visual search tool that turns a social media feed into a personal online store | $415K | 126 mo ago | — | David G Ortega Co-Founder & CTO | — | — | — | — |
| 18 | Blueshift Manufacturer of polymer-based aerogel materials | $100K | 148 mo ago | 18 18 → 25 (+39%) | — | Cart FunctionalityWooCommerceWordPress+26 | Top 5M | 45 patents Patents concentrated in electrical & electronics | — |
Top 12 High Tech companies in San Antonio
#1
Series A · San Antonio, Texas · founded 2021 · 8 employees$25Mraised▾
Developer of autonomous drone systems designed to intuitively interact with robotics platforms in order to understand their common environment and make decisions together. The company offers a core software suite and a palm-sized autonomous drone that is optimized to demonstrate the capabilities of its software stack, enabling military and public safety robotics systems to integrate with the existing military equipment and create human-machine teams.
#2
Acquired · San Antonio, Texas · founded 2011 · 12 employees$3.2Mraised▾
Developer of patented small cell technology and wide area networks designed to support 5G cellular and fixed wireless network coverage throughout the United States. The company's technology offers in-building and citywide 5G solutions utilizing multiple 5G equipment vendors in combination with its patented LPN-16 small cell technology to complete its network designs, currently, its focus is on America's independent school districts with emphasis on student safety and distant learning, enabling users to enjoy the wireless infrastructure and telecommunications services intended to drive access and adoption of gigabit data
#3
Series C · San Antonio, Texas · founded 2015 · 102 employees$100Mraised▾
Provider of AI-powered vision software for warehouse automation and robotics. The company offers systems for induction, depalletizing, and palletizing processes. It provides a supervised autonomy platform designed to resolve edge cases. The company's systems are designed for speed and accuracy in real-world environments.
- Mar 2023Series C$50M
- Apr 2021Series B$34.5M
- Nov 2018Series A$8.3M
- May 2018Seed$2.4M
#4
Series D · San Antonio, Texas · founded 2009 · 79 employees$94.4Mraised▾
Xenex provides disinfection robots for multiple healthcare purposes. It offers hospital sterilization robots that use strong, ultraviolet lights (termed patented Xenon Pulse or UV technology) to kill infection-causing microorganisms. Their patented room disinfection system reduces the bacterial load that is often associated with an increased risk for healthcare-associated infections (HAIs).
- Feb 2019Series D$6M
- Feb 2018Series D$40M
- Sep 2016Series C$3M
- Jan 2015Series C$25M
#5
Funding Raised · San Antonio, Texas · founded 2016 · 6977 employees$924.7Kraised▾
AI-powered forecasting solutions for grid resilience and operational foresight. The company provides advanced forecasting solutions leveraging Artificial Intelligence and Machine Learning to strengthen grid resilience and improve operational foresight. It offers a suite of forecasting products including solar, ISO, and net load forecasting, utilizing hybrid forecast algorithms and advanced weather data integration. The solutions cater to utilities, independent power producers, ISOs, market participants, microgrids, datacenters, and government agencies. The company's technology is built on research and delivers real-time forecasts validated in production environments. It is a technology company offering software solutions that enable data-driven decisions, improve market coordination, and enhance grid stability.
- Sep 2023Grant (prize money)$650K
- Jul 2022Grant (prize money)$125K
- Jun 2017Grant (prize money)$149.7K
#6
Series B · San Antonio, Texas · founded 2012 · 22 employees$60.5Mraised▾
WellAware provides end-to-end solutions for oilfield data collection, storage, visualization, and decision analysis. It offers a solution for remote monitoring to manage production and pipeline assets, and display trending information. The company also offers LIFT Field Capture that provides input screens for flow computers, tank levels, pressure sensors, and other measurement devices.
- Sep 2015Series B$16M
- Jul 2014Series B$37M
- Jan 2014Series A$1M
- Jun 2013Series A$6.5M
#7
Series A · San Antonio, Texas · founded 2018 · 68 employees$7.1Mraised▾
Provider of a solar panel management robot system. Its product portfolio includes solar robots, chargers, and accessories. It enables users to clean, spray, and inspect solar panels. Its offering includes inspection tools, footage, and cleaning tools.
- Dec 2021Series A$6.5M
- Apr 2020Seed$578K
#8
Series C · San Antonio, Texas · founded 1998 · 69 employees$25Mraised▾
Cloud based platform offering secure communication solutions. Some of the features of the platform include inbound call verification, call authentication, and spoofing detection, malicious call monitoring and reporting, and more. It provides solutions for banking and financial services, energy, healthcare, and more.
- Apr 2003Series C$4.2M
- Feb 2002Series B$10.4M
- Oct 2000Series A$7.5M
- 1999Unattributed$2.9M
#9
Public · San Antonio, Texas · founded 2015 · 10 employees$1.5Mraised▾
Provider of monitoring services to health insurers for diabetic neuropathy patients
- Jul 2022Series A$1.1M
- Dec 2019Seed$225K
- Aug 2015Seed$150K
#10
Series A · San Antonio, Texas · founded 2014 · 21 employees$10.1Mraised▾
Merge Labs provides an augmented and virtual reality-based educational solution. Offers Merge Cube, headset, Miniverse, and EDU platform for classrooms, libraries, STEM labs, and maker spaces. It enables users to touch & hold science lessons, interact with STEM concepts in a superimposed environment, and be transported to virtual places. It is available on a subscription-based pricing model.
- May 2016Series A$10.1M
- Dec 2014Series A$1.1M
- Apr 2014Seed$310K
#11
Series A · San Antonio, Texas · founded 2013 · 57 employees$6.4Mraised▾
Provider of hardware and software solutions for the hospitality industry. They enable vendors with multiple vending machines to manage them through a cloud-based single platform. Through the platform, they can retrieve insights, and take necessary steps to reduce operational costs and maximize their profit. The features they provide include advanced analytics, pre kitting, mobile access, route monitoring, and optimization, performance management, inventory management, etc., and other operational tracking ranging from the vendor's warehouse to the field.
- Feb 2017Series A$1.1M
- Nov 2015Series A$2.5M
- Sep 2015Conventional Debt$2M
- Aug 2013Seed$830.3K
#12
Acqui-Hired · San Antonio, Texas · founded 2003 · 11 employees$4.6Mraised▾
Developer of small molecule liposomal formulations for cancer therapy. The lead product ATI-1123, a liposomal formulation of docetaxel, is the active ingredient in Taxotere for multiple solid tumor cancers. It is also developing ATI-0198, a generic formulation of Doxil/Caelyx, a liposomal formulation of doxorubicin hydrochloride.
- May 2011Conventional Debt$3M
- Sep 2009PE$1M
- Oct 2007Series A$3.6M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of High Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Semiconductors is moving in the United States
A read on the academic research around Semiconductors — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,739 United States-affiliated papers.
- Georgia Institute of Technology489
- IMEC343
- Intel325
- Purdue University West Lafayette218
- Industrial Technology Research Institute177
- Photonics56→121
- Photonic integrated circuit49→81
- Artificial neural network3→29
- Detector25→48
- Scalability53→73
- Photonics45→59
- Artificial neural network2→14
- Rapid single flux quantum2→12
- Detector20→29
- Image sensor2→11
- Photonics10→28
- Hardware security module6→13
- Thermal10→16
- Automotive industry2→8
- Photonic integrated circuit9→14
Where semiconductors is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing semiconductors patents in the United States
United States semiconductors patent filing is cooling — 112,775 filings from 8,000 assignees (2016–2025), led by IBM, Applied Materials, Intel; annual filings 11572→7675.
- IBM19691
- Applied Materials13119
- Intel11689
- Micron Technology10011
- Texas Instruments4804
- LAM RES4667
- Sandisk Technologies3051
- Qualcomm2897
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.