Best Internet of Things - Industry Applications Companies in Irvine, United States
The 54 best Internet of Things - Industry Applications companies in Irvine, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: CalAmp.
Our analysis of 77 Internet of Things - Industry Applications companies
$9.7b in tracked funding; 93% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Internet of Things - Industry Applications companies in Irvine
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | CalAmp Provider of telematics products, cloud services, and applications for various industries | $627M | 96 mo ago | 644 644 → 714 (+11%) | — | WordPressApple iCloud MailMicrosoft 365+27 | Top 5M | 233 patents Patents concentrated in electrical & electronics | 1 internship · 1 award |
| 2 | Ivantis Innovative microstent solutions for glaucoma management and surgical eye care | $166M | 113 mo ago | 132 | — | — | — | 149 patents Patents concentrated in health & consumer products | — |
| 3 | Masimo Provider of wide range of devices to monitor health parameters | $151M | 47 mo ago | 2,200 2,200 → 3,672 (+67%) | Joe Kiani Founder | Apple iCloud MailVimeoYouTube+19 | Top 5M | 2,303 patents Non‑invasive multi‑parameter patient monitoring, especially pulse oximetry and signal processing | 2 launchs · 1 expansion |
| 4 | Syntiant Provider of neural processing units for edge computing applications | $121M | 34 mo ago | 95 | Kurt Busch CEO | Cart FunctionalitySquarespace CommerceSquarespace+17 | Top 5M | 109 patents Ultra‑low‑power neuromorphic AI chips for edge audio and sensor inference. | 2 launchs · 1 partnership |
| 5 | Greenwave Systems Developer of software-defined network platform enabling virtual network operator capabilities | $86M | 126 mo ago | 13 | — | — | — | — | — |
| 6 | Breathe Technologies Portable respiratory therapy systems | $60M | 98 mo ago | 97 | — | — | — | 371 patents Non‑invasive mechanical ventilation hardware and integrated patient‑interface jet pump systems | — |
| 7 | HyperIce Internet first brand offering smart devices for physical fitness | $52M | 36 mo ago | 175 | Jim Huether CEO | Cart FunctionalityShopifyApple iCloud Mail+30 | Top 500k | 2 patents Phototherapy and exercise recovery devices for therapeutic light and muscle regeneration | 2 launchs |
| 8 | NGD Systems Developer of SSD storage systems | $45M | 77 mo ago | 34 | — | WordPress Block EditorWordPressMySQL+16 | Top 5M | — | — |
| 9 | Tahmo Provider of smart devices to monitor vital health | $31M | 94 mo ago | 2 | Arif Quronfleh Founder | — | — | — | — |
| 10 | Phoenix Energy Technologies AI-powered facilities intelligence for smarter, sustainable building performance | $17M | 86 mo ago | 85 85 → 50 (-41%) | — | HubSpot CMS HubSalesforceAmazon Web Services+17 | Top 50M | — | — |
| 11 | Location Based Technologies GPS trackers for asset tracking and monitoring | $12M | 173 mo ago | 16 | Dave Morse CEO & Co-President | — | — | 57 patents Location-based mapping, navigation, and tracking systems for vehicles and asset management | — |
| 12 | Flint Rehab Developer of stroke rehabilitation systems | $8M | 15 mo ago | 9 | — | Cart FunctionalityWooCommerceWordPress+22 | Top 500k | — | — |
| 13 | Cercacor Blood hemoglobin monitoring device for athletes | $8M | 103 mo ago | 59 59 → 118 (+100%) | — | — | — | — | — |
| 14 | SkyBell Provider of Wifi doorbell with camera and motion sensor | $5M | 52 mo ago | 46 | Joseph Scalisi Founder President Chief Information Officer-Skybell | Cart FunctionalityShopifySentry+32 | Top 5M | 188 patents Smart doorbell and integrated home security camera systems for residential IoT. | — |
| 15 | Capillary Biomedical Provider of implants for continuous glucose monitoring | $3M | 69 mo ago | 1,922 | — | — | — | 19 patents Subcutaneous insulin infusion devices with advanced insertion and delivery control mechanisms. | — |
| 16 | Aggios Software defined Power Management for micro devices | $2M | 139 mo ago | 3 | — | — | — | 7 patents Patents concentrated in computing, sensing & instrumentation | — |
| 17 | Allevion Therapeutics Developer of smart wearable for the treatment of essential tremors and other movement-related disorders | $1M | 28 mo ago | 3 | — | — | — | — | — |
| 18 | Vena Vitals Provider of wearable sticker for monitoring blood pressure | $1M | 34 mo ago | 10 | Michelle Khine Co-Founder | — | — | 6 patents Wearable multi‑channel sensor arrays for real‑time physiological signal monitoring | — |
| 19 | TinyKicks Fetal sensor to detect baby movement | $1M | 114 mo ago | — | Michelle Khine Co-Founder | — | — | — | — |
| 20 | Nouslogic Smart home access and automation solutions for enhanced security | $300K | 85 mo ago | — | Hoang Nhu Founder & CEO | — | — | — | — |
| 21 | ACS Diagnostics Provider of ECG monitoring device | $300K | 146 mo ago | 37 | — | WordPressMySQLPHP+37 | Top 50M | — | — |
Top 12 Internet of Things - Industry Applications companies in Irvine
#1
Early Stage · Irvine, California · founded 2011 · 9 employees$8Mraised▾
Developer of stroke rehabilitation systems. The company has developed personalized neurorehabilitation devices which includes FitMi a full-body neuro-rehab device, and Musicglove - a music-based hand therapy
- Apr 2025Grant (prize money)$2M
- Sep 2024Grant (prize money)$950.8K
- Sep 2021Grant (prize money)$1.7M
- Sep 2021Grant (prize money)$100K
#2
Series C · Irvine, California · founded 2017 · 95 employees$121.4Mraised▾
Provider of neural processing units for edge computing applications. It develops hardware machine learning solutions for battery-powered devices. It uses its patented analogue neural network technology in flash memory and develops neural decision processors (NDP). The processors perform neural network computations in flash memory, and enable network communication at lower power. It is suited for high computational workloads for real-time applications at ultra-low-power. It has applications in multiple battery-powered devices, including smartphones, wearables, remote controls, drones, sensors, and security cameras.
- Sep 2023Series C$56.4M
- Aug 2020Series C$35M
- Oct 2018Series B$25M
- May 2018Series A—
#3
Series C · Irvine, California · founded 2011 · 175 employees$52.5Mraised▾
Internet first brand offering smart devices for physical fitness. It develops muscle recovery, rehabilitation, and ice compression wraps for knees, ankles, shoulders, backs, wrists, and elbows. It provides ice compression therapy devices with patented air release technology. It also offers a fitness and recovery device that uses pressure and vibration to improve the body's overall performance.
- Jul 2023Venture Debt$100M
- Nov 2021Series C—
- Oct 2020Series C$48M
- Sep 2018Angel—
#4
Acquired · Irvine, California · founded 1989 · 2200 employees$151.2Mraised▾
Provider of wide range of devices to monitor health parameters. The company offers a wide range of products across various categories include wearables Masimo W1 that provides untethered continuous pulse oximetry with visual and haptic notifications, Masimo W1 sport to track hydration levels, wireless earbuds with Masimo Adaptive Acoustic Technology for personalized sound, and Baby Monitoring Masimo Stork that tracks temperature, pulse rate, and oxygen saturation.
- Aug 2022Post IPO—
- Dec 2018Conventional Debt$150M
- Aug 2016Grant (prize money)$1.2M
#5
Public · Irvine, California · founded 1981 · 644 employees$627.2Mraised▾
Provider of telematics products, cloud services, and applications for various industries. The company offers hardware, including edge devices and device management tools. It also provides a telematics cloud platform with data streaming services. Applications include fleet management, video safety, and solutions for trucking, asset tracking, and connected car services.
- Jul 2018Post IPO$200M
- Jul 2018Post IPO$230M
- May 2015Post IPO$150M
- Feb 2010Post IPO$9.2M
#6
Acquired · Irvine, California · founded 2007 · 132 employees$166.2Mraised▾
Innovative microstent solutions for glaucoma management and surgical eye care. This company focuses on providing advanced medical devices and solutions for eye health, specifically in the areas of glaucoma and cataract surgery. They offer a range of products including intraocular lenses (IOLs), surgical equipment, procedural eye drops, and disposables. Their flagship product, the Hydrus Microstent, is a minimally invasive glaucoma surgery (MIGS) device designed to reduce intraocular pressure in patients with mild to moderate primary open-angle glaucoma. The company emphasizes evidence-based outcomes and long-term safety in their product development. They also provide resources and training for eye care professionals through platforms like the Alcon Experience Academy. The company supports vision care and surgical customers through digital platforms, offering convenient access to eye health essentials and seamless eCommerce experiences.
- Jan 2017Series C$25M
- Oct 2014Series C$58.9M
- Jan 2014Series B$14M
- Aug 2013Series B$5M
#7
Seed · Irvine, California · founded 2017 · 3 employees$1.5Mraised▾
Developer of smart wearable for the treatment of essential tremors and other movement-related disorders. The device can be worn around the wrist or ankle for delivering multimodal stimulation with proprietary delivery algorithms to reduce tremors. Its device learns and adjusts the use of each stimulation modality to optimize patient response.
- Mar 2024Seed$1.5M
- May 2018Seed—
#8
Deadpooled · Irvine, California · founded 2013 · 34 employees$45Mraised▾
Developer of SSD storage systems. It offers a converged platform that provides enterprise SSD storage capabilities and computes resources. Its product is optimized for applications requiring consistent and low-latency mass storage.
- Feb 2020Series C$20M
- Feb 2018Series B$12.4M
- Feb 2018Conventional Debt$4M
- Mar 2017Grant (prize money)$1.4M
#9
Acquired · Irvine, California · founded 2005 · 97 employees$60Mraised▾
Breathe Technologies is a developer and manufacturer of medical technologies for treating lung diseases and sleep-disordered breathing. Breathe's wearable ventilator, NIOV, weighs only one pound, fits in the palm of the hand, and has a battery that lasts up to 4 hours before needing to be recharged. NIOV delivers a mixture of oxygen and air through a nasal interface. NIOV nasal interface covers just the nostrils, leaving the mouth unobstructed so that the patient can speak while the device is in use. NIOV requires a pressure source to work, therefore it needs an oxygen cylinder or other pressurized oxygen sources. It features the company’s proprietary, portable, open-airway platform, and is FDA cleared for patients with respiratory insufficiency such as those with COPD, Interstitial Lung disease, Post Lung transplant, Neuromuscular disorders. It is commercially available for both the institutional and homecare settings. Investors include KPCB, Johnson & Johnson, Delphi Ventures, Synergy Ventures, DAG Ventures, and Morgan Creek.
- May 2018Conventional Debt—
- Oct 2017Series D$6.3M
- Aug 2017Series D$8.5M
- Jun 2014Series C$7.2M
#10
Series C · Irvine, California · founded 2008 · 13 employees$86.3Mraised▾
Developer of software-defined network platform enabling virtual network operator capabilities. The platform allows customers to offer connected services without infrastructure ownership. It enables device manufacturers to deploy devices with connectivity services, customer support, and worldwide coverage. The platform also allows control of data services.
- Jan 2016Series C$45.1M
- Jan 2016Conventional Debt$15M
- Sep 2013Series B$19M
- Jun 2010Series A$11M
#11
Seed · Irvine, California · founded 2019 · 10 employees$1.4Mraised▾
Provider of wearable sticker for monitoring blood pressure. The sticker contains soft stretchable sensors that measure continuous blood pressure and provides an understanding of cardiovascular health.
- Aug 2023Seed—
- Aug 2023Grant (prize money)$295.9K
- May 2022Grant (prize money)$842.8K
- Feb 2021Grant (prize money)$256K
#12
Series A · Irvine, California · founded 2013 · 46 employees$4.8Mraised▾
Provider of Wifi doorbell with camera and motion sensor. When a visitor presses the button, SkyBell alerts the user and allows them to see, hear and speak to the person via smartphone. Support iOS and Android devices. It works with Nest and Apple Homekit.
- Mar 2022Series A$4M
- Jun 2016Seed$100K
- Jul 2015Seed$750K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Internet of Things - Industry Applications coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Iot in Irvine is moving
A read on the academic research around Iot in Irvine — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 43 papers.
UC Irvine leads Irvine's optimistic IoT research (mean stance 0.64), focusing dominantly on edge/fog computing and neural networks, with breakthroughs far outpacing concerns (28 vs 6).
- University of California, Irvine39
- Irvine University6
- UC Irvine Health2
- Concordia University Irvine1
- Irvine Valley College1
- Wireless sensor network1→9
- Wireless sensor network2
- Internet of Things2
- Computer network1
- Relay1
- Routing protocol1
- Internet of Things2
- Computer security2
- Posthuman2
- Anthropocentrism2
- Posthumanism2
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.