Best Medical Devices Companies in United States
The 886 best Medical Devices companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Paradigm Spine.
Tracking the top Medical Devices companies in the United States by disclosed equity funding, this directory covers 886 firms with $340M in total capital on the books. Paradigm Spine leads the pack at $104M raised, followed closely by Senseonics at $96M, and the numbers tell you something real: a handful of outsized earners are pulling the aggregate while the long tail is still early-stage. The global medical devices market sits at roughly $678.9B in 2025, growing at 6.0% CAGR, and stringent regulatory requirements, particularly around FDA compliance and data security, are shaping which startups actually survive to Series B. As 2020 research shows, digital health integration is accelerating device utility in ways that make regulatory readiness less optional than ever.
So what's moving right now? App-layer momentum is a useful proxy: median install growth across 129 medical devices, therapeutic devices, and medical practice apps hit roughly +19% YoY, which isn't a vanity metric when it tracks alongside rising coverage of medical AI applications and risk management frameworks. I'd watch the mid-tier closely, companies like Aptus Endosystems ($70M) and Precise Light Surgical ($9M) represent the bracket where category-defining bets are still being made. And a recent $72M investment into Sensa Core signals that global capital is actively hunting for the next breakout in this space.
Ranked: Best Medical Devices companies in United States
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Paradigm Spine Developer of non-fusion spinal implant technology intended to provide products that are surgeon-centric… | $104M | 138 mo ago | Acquired | — | 2005 | WordPressApple iCloud MailMicrosoft 365+23 | 196 patents Spinal fixation devices: modular interspinous/interlaminar stabilization and implantation instruments | — |
| 2 | senseonics Senseonics is a medical device startup company that focuses on the design, development, and commercialization… | $96M | 64 mo ago | Public | — | 1996 | Apple iCloud MailSalesforceMicrosoft ASP.NET+14 | 689 patents Implantable continuous glucose monitoring sensors and calibration/analytics algorithms | 4 job openings |
| 3 | aptus endosystems Aptus Endosystems is a medical tech company engaged in developing EVAR technologies for abdominal aortic… | $70M | 167 mo ago | Acquired | — | 2002 | — | 134 patents Endovascular surgical stapling and prosthesis delivery systems for minimally invasive organ repair | — |
| 4 | watermark medical Watermark Medical provides home sleep testing solutions to enhance ongoing patient care and sleep disorder… | $55M | 158 mo ago | Series C | — | 2008 | WebflowAmazon Web ServicesTypekit+15 | — | — |
| 5 | precise light surgical Precise Light Surgical was incorporated in 2008 and is based in Sunnyvale, California. | $9M | 71 mo ago | Deadpooled | — | 2008 | — | — | — |
| 6 | Metric (Therapeutic Devices) Developer of internal bone fixation implants designed to advance the musculoskeletal repair standard of care. | $4M | 43 mo ago | Series A | — | 2009 | — | — | — |
| 7 | Veritract Developer of feeding tubes designed to prevent unnecessary deaths or serious health complications. | $820K | 182 mo ago | Deadpooled | — | 2010 | — | 16 patents Optical navigation systems for feeding tubes and elongated medical instruments with sheaths | — |
| 8 | nasaclip NasaClip provides your body with the constant, uninterrupted pressure it requires to complete its natural… | $250K | 39 mo ago | Seed | — | 2015 | Cart FunctionalityShopifyVue.js+31 | 5 patents Nasal drug delivery and compression devices for controlled intranasal therapy | — |
| 9 | cryothermic systems, inc. Cryothermic Systems is a medical device firm that develops a series of products to improve patient outcomes… | $250K | 170 mo ago | Seed | — | 2008 | — | — | — |
Top 10 Medical Devices companies in United States
#1
Series A · United States · founded 2009 · 12 employees$4.4Mraised▾
Developer of internal bone fixation implants designed to advance the musculoskeletal repair standard of care. The company's implants specialize in a nitinol-made substance that yields immediate, secure fixation by continuously compressing the bones for healing thereby offering a constant, uniform compression and a proper shape, enabling surgeons to minimize the number of surgical steps for implantation and reduce procedural time.
#2
Seed · Baltimore, Maryland · founded 2015 · 6 employees$250Kraised▾
Developer of a medical device designed to help control nosebleeds in children and adults. The company's nasal clip comes in adjustable sizes and applies constant hands-free pressure to the soft side walls of the nose and incorporates pre-medicated sponges to help deliver vasoconstrictive medication that can control bleeding, providing patients an optional facial cooling pack to help constrict vessels and reduce inflammation.
#3
Public · Germantown, Maryland · founded 1996 · 121 employees$96.1Mraised▾
Senseonics Holdings Inc is a medical technology company. It is focused on the design, development, and commercialization of the glucose monitoring system, which helps people to manage their diabetes community with differentiated, long-term implantable glucose management technology. Its products and services include a Continuous glucose monitoring system, Sensor, Smart transmitter, and Mobile app. The firm has a Glucose monitoring product segment. The majority of the revenue is generated outside of the United States.
#4
Deadpooled · Sunnyvale, California · founded 2008 · 4 employees$9.4Mraised▾
Developer of surgical devices designed to provide minimally invasive surgical resection services that preserve critical anatomy. The company's technology is based on flash vaporization technology that provides unprecedented precision and control for the removal of delicate tissues with nerve and vessel sparing capability, enabling doctors to reduce the cost associated and also the surgical risk and downtime in the procedure.
#5
Acquired · United States · founded 2005 · 10 employees$103.7Mraised▾
Developer of non-fusion spinal implant technology intended to provide products that are surgeon-centric, indication-specific and data-driven. The company is engaged in the development of a full non-fusion product portfolio of tissue-sparing devices for the treatment of spinal disorders, enabling patients suffering from lumbar spinal stenosis and age-related spinal deformities to receive differentiated, minimally invasive motion-preserving stabilization implants.
#6
Acquired · Sunnyvale, California · founded 2002 · 75 employees$70Mraised▾
Developer of advanced technology for endovascular aneurysm repair. The company engages in the development of next generation invasive endograft devices, delivery systems and fixation technology for the treatment of Abdominal Aortic Aneurysms.
#7
Series C · West Palm Beach, Florida · founded 2008 · 39 employees$55.3Mraised▾
Provider of diagnostic testing tools intended to treat sleep disorder. The company's tools integrate physiological data acquired in-home, along with clinical history and anthropomorphic data to determine the presence and severity of obstructive sleep apnea (OSA), enabling patients to have a peaceful sleep.
#8
Deadpooled · United States · founded 2010 · 4 employees$819.5Kraised▾
Developer of feeding tubes designed to prevent unnecessary deaths or serious health complications. The company's feeding tubes are developed with integrated optics and steering allowing precision tube placement and confirmation in the GI tract through direct vision, enabling doctors to inspect and monitor internal body organs with accuracy.
#9
Seed · Cleveland, Ohio · founded 2008 · 5 employees$250Kraised▾
Manufacturer of medical devices intended to cool the body of patients without the usage of electrical power, refrigeration and external equipment. The company's device is inserted into the cooling collar, which holds the pack in place to extract heat from the vessels in the neck to initiate and continue cooling, for prehospital use by the emergency medical service (EMS) or in the intensive care unit (ICU) for fever control and lowering the body temperature, enabling healthcare providers to protect patients suffering from ischemic and reperfusion injury effects of cardiac arrest, heart attack, stroke and traumatic brain injury.
#10
Funding Raised · Berkeley, California · founded 2003 · 4 employees—raised▾
Developer of wireless brain-machine devices designed to help with the diagnosis and treatment of incurable neurological conditions. The company's devices aim to deliver products that improve patient care, quality of life, and advanced neuroscientific research, enabling medical professionals to offer integrated circuit technology for brain sensing and stimulation.
Funding & investor landscape
Market landscape — 10 sub-themes by coverage
Share of Medical Devices coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Medical Devices is moving in the United States
A read on the academic research around Medical Devices — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,830 United States-affiliated papers.
- Johns Hopkins University74
- United States Food and Drug Administration59
- Harvard University54
- Center for Devices and Radiological Health53
- Design Intelligence36
- Biocompatible material2→9
- Robotics7→13
- Health care1→6
- Tissue engineering1→5
- Automation1→5
- Health care2→24
- MEDLINE1→21
- Quality (philosophy)3→15
- Robotic surgery18→29
- Product (mathematics)5→16
- MEDLINE1→36
- Robotic surgery7→24
- Patient safety19→32
- Key (lock)6→19
- Quality (philosophy)10→20
Where medical devices is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
- Covidien29351
- Boston Scient Scimed24775
- Medtronic22434
- Becton Dickinson18269
- Procter & Gamble16210
- Ethicon ENDO Surgery13758
- Kimberly Clark12462
- Ethicon11769