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Radar · Medical Devices in United States

Best Medical Devices Companies in United States

The 886 best Medical Devices companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Paradigm Spine.

886companies tracked
$340.1Mdisclosed funding
0unicorns
9have raised

Tracking the top Medical Devices companies in the United States by disclosed equity funding, this directory covers 886 firms with $340M in total capital on the books. Paradigm Spine leads the pack at $104M raised, followed closely by Senseonics at $96M, and the numbers tell you something real: a handful of outsized earners are pulling the aggregate while the long tail is still early-stage. The global medical devices market sits at roughly $678.9B in 2025, growing at 6.0% CAGR, and stringent regulatory requirements, particularly around FDA compliance and data security, are shaping which startups actually survive to Series B. As 2020 research shows, digital health integration is accelerating device utility in ways that make regulatory readiness less optional than ever.

So what's moving right now? App-layer momentum is a useful proxy: median install growth across 129 medical devices, therapeutic devices, and medical practice apps hit roughly +19% YoY, which isn't a vanity metric when it tracks alongside rising coverage of medical AI applications and risk management frameworks. I'd watch the mid-tier closely, companies like Aptus Endosystems ($70M) and Precise Light Surgical ($9M) represent the bracket where category-defining bets are still being made. And a recent $72M investment into Sensa Core signals that global capital is actively hunting for the next breakout in this space.

Ranked: Best Medical Devices companies in United States

#CompanyDisclosed fundingLast roundStageFounderFoundedTech stackPatents & IP focusRecent signals
1Paradigm Spine
Developer of non-fusion spinal implant technology intended to provide products that are surgeon-centric…
$104M138 mo agoAcquired—2005WordPressApple iCloud MailMicrosoft 365+23196 patents
Spinal fixation devices: modular interspinous/interlaminar stabilization and implantation instruments
—
2senseonics
Senseonics is a medical device startup company that focuses on the design, development, and commercialization…
$96M64 mo agoPublic—1996Apple iCloud MailSalesforceMicrosoft ASP.NET+14689 patents
Implantable continuous glucose monitoring sensors and calibration/analytics algorithms
4 job openings
3aptus endosystems
Aptus Endosystems is a medical tech company engaged in developing EVAR technologies for abdominal aortic…
$70M167 mo agoAcquired—2002—134 patents
Endovascular surgical stapling and prosthesis delivery systems for minimally invasive organ repair
—
4watermark medical
Watermark Medical provides home sleep testing solutions to enhance ongoing patient care and sleep disorder…
$55M158 mo agoSeries C—2008WebflowAmazon Web ServicesTypekit+15——
5precise light surgical
Precise Light Surgical was incorporated in 2008 and is based in Sunnyvale, California.
$9M71 mo agoDeadpooled—2008———
6Metric (Therapeutic Devices)
Developer of internal bone fixation implants designed to advance the musculoskeletal repair standard of care.
$4M43 mo agoSeries A—2009———
7Veritract
Developer of feeding tubes designed to prevent unnecessary deaths or serious health complications.
$820K182 mo agoDeadpooled—2010—16 patents
Optical navigation systems for feeding tubes and elongated medical instruments with sheaths
—
8nasaclip
NasaClip provides your body with the constant, uninterrupted pressure it requires to complete its natural…
$250K39 mo agoSeed—2015Cart FunctionalityShopifyVue.js+315 patents
Nasal drug delivery and compression devices for controlled intranasal therapy
—
9cryothermic systems, inc.
Cryothermic Systems is a medical device firm that develops a series of products to improve patient outcomes…
$250K170 mo agoSeed—2008———

Top 10 Medical Devices companies in United States

#1
Series A · United States · founded 2009 · 12 employees
$4.4Mraised
▾

Developer of internal bone fixation implants designed to advance the musculoskeletal repair standard of care. The company's implants specialize in a nitinol-made substance that yields immediate, secure fixation by continuously compressing the bones for healing thereby offering a constant, uniform compression and a proper shape, enabling surgeons to minimize the number of surgical steps for implantation and reduce procedural time.

Investors
Houston Angel Network
#2
Seed · Baltimore, Maryland · founded 2015 · 6 employees
$250Kraised
▾

Developer of a medical device designed to help control nosebleeds in children and adults. The company's nasal clip comes in adjustable sizes and applies constant hands-free pressure to the soft side walls of the nose and incorporates pre-medicated sponges to help deliver vasoconstrictive medication that can control bleeding, providing patients an optional facial cooling pack to help constrict vessels and reduce inflammation.

Investors
TEDCO, Springboard Enterprises
#3
Public · Germantown, Maryland · founded 1996 · 121 employees
$96.1Mraised
▾

Senseonics Holdings Inc is a medical technology company. It is focused on the design, development, and commercialization of the glucose monitoring system, which helps people to manage their diabetes community with differentiated, long-term implantable glucose management technology. Its products and services include a Continuous glucose monitoring system, Sensor, Smart transmitter, and Mobile app. The firm has a Glucose monitoring product segment. The majority of the revenue is generated outside of the United States.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 18k LinkedIn followers — 73.4% of this cohort's audience · 35 engagements/post (1.6× cohort median)
Hiring: 4 hiring posts in 12 mo (public) · momentum +4 · hiring: Territory Manager, Director of Information Technology
Investors
Roche, New Enterprise Associates, Oxford Finance, Anthem Capital, Delphi Ventures, Greenspring Associates
Tech stack
Amazon AlbAmazon Web ServicesApple Icloud MailCloudflareCloudflare Bot ManagementCloudflare Browser Insights
#4
Deadpooled · Sunnyvale, California · founded 2008 · 4 employees
$9.4Mraised
▾

Developer of surgical devices designed to provide minimally invasive surgical resection services that preserve critical anatomy. The company's technology is based on flash vaporization technology that provides unprecedented precision and control for the removal of delicate tissues with nerve and vessel sparing capability, enabling doctors to reduce the cost associated and also the surgical risk and downtime in the procedure.

Investors
Easton Capital Investment Group, Southern Cross Venture Partners
#5
Acquired · United States · founded 2005 · 10 employees
$103.7Mraised
▾

Developer of non-fusion spinal implant technology intended to provide products that are surgeon-centric, indication-specific and data-driven. The company is engaged in the development of a full non-fusion product portfolio of tissue-sparing devices for the treatment of spinal disorders, enabling patients suffering from lumbar spinal stenosis and age-related spinal deformities to receive differentiated, minimally invasive motion-preserving stabilization implants.

Investors
PDL Biopharma, Fifth Third Bancorp, Trevi Health Ventures, Praefinium Partners, HealthCor Partners, HealthCor Management
Tech stack
Animate.CssApple Icloud MailCloudflareCloudflare Browser InsightsCloudflare TurnstileDivi
#6
Acquired · Sunnyvale, California · founded 2002 · 75 employees
$70Mraised
▾

Developer of advanced technology for endovascular aneurysm repair. The company engages in the development of next generation invasive endograft devices, delivery systems and fixation technology for the treatment of Abdominal Aortic Aneurysms.

Investors
Synergy Life Science Partner, VCDE Venture Partners, Longitude Capital, USVP, Oakwood Medical, Heron Capital
#7
Series C · West Palm Beach, Florida · founded 2008 · 39 employees
$55.3Mraised
▾

Provider of diagnostic testing tools intended to treat sleep disorder. The company's tools integrate physiological data acquired in-home, along with clinical history and anthropomorphic data to determine the presence and severity of obstructive sleep apnea (OSA), enabling patients to have a peaceful sleep.

Investors
Ballast Point Ventures, CA Technologies, Yet2ventures, Kestrel Investments
Tech stack
Amazon SesAmazon Web ServicesCloudflareGoogle AnalyticsGoogle Font ApiGoogle Hosted Libraries
#8
Deadpooled · United States · founded 2010 · 4 employees
$819.5Kraised
▾

Developer of feeding tubes designed to prevent unnecessary deaths or serious health complications. The company's feeding tubes are developed with integrated optics and steering allowing precision tube placement and confirmation in the GI tract through direct vision, enabling doctors to inspect and monitor internal body organs with accuracy.

Investors
Kickstart Seed Fund, Salt Lake Life Science Angels, University Venture Fund, University of Utah, UpStart Ventures
#9
Seed · Cleveland, Ohio · founded 2008 · 5 employees
$250Kraised
▾

Manufacturer of medical devices intended to cool the body of patients without the usage of electrical power, refrigeration and external equipment. The company's device is inserted into the cooling collar, which holds the pack in place to extract heat from the vessels in the neck to initiate and continue cooling, for prehospital use by the emergency medical service (EMS) or in the intensive care unit (ICU) for fever control and lowering the body temperature, enabling healthcare providers to protect patients suffering from ischemic and reperfusion injury effects of cardiac arrest, heart attack, stroke and traumatic brain injury.

Investors
Jumpstart Ventures, VentureHealth, BioEnterprise, Rev1 Ventures, Global Cardiovascular Innovation Center, North Coast Ventures
#10
Funding Raised · Berkeley, California · founded 2003 · 4 employees
—raised
▾

Developer of wireless brain-machine devices designed to help with the diagnosis and treatment of incurable neurological conditions. The company's devices aim to deliver products that improve patient care, quality of life, and advanced neuroscientific research, enabling medical professionals to offer integrated circuit technology for brain sensing and stimulation.

Investors
Melbourne Accelerator Program, CITRIS Foundry, Berkeley SkyDeck
Tech stack
ErlangCowboy

Funding & investor landscape

$340.1Mtotal disclosed funding
9companies funded
0disclosed rounds
0rounds last 90 days
Prism market signals · United States · country-scoped Prism corpus, 693,627 docs

Market landscape — 10 sub-themes by coverage

Share of Medical Devices coverage by sub-theme.

Regulatory-risk over time rising

Funding & growth over time

funding rising · growth rising

RESEARCH SIGNALS · United States

How research on Medical Devices is moving in the United States

A read on the academic research around Medical Devices — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,830 United States-affiliated papers.

research sentiment over time
200820172026
enthusiastic · positive · guarded tone
Tone is overwhelmingly optimistic and intensifying — the enthusiastic (strongly-positive) share moved 43% → 57% across 2008–2026.
top research entities
  • Johns Hopkins University74
  • United States Food and Drug Administration59
  • Harvard University54
  • Center for Devices and Radiological Health53
  • Design Intelligence36
leading researchers
www.rasitdinc.com · , Elena · Dmitry Oleynikov · Joseph S. Ross · Shane Farritor · Carl A. Nelson · Raşit Dinç · Barbara Christe
▲ Breakthroughs295 · 16%
▲ 15%→16% share
▲1.1× share momentum1 median citations53% since 2021mostly methods-led
Robotics research is surging — U.S. biocompatible-material papers nearly quintupled (2→9) and robotics doubled (7→13) in Breakthroughs.
rising sub-themes (early→recent)
  • Biocompatible material2→9
  • Robotics7→13
  • Health care1→6
  • Tissue engineering1→5
  • Automation1→5
Newly emergingWearable computer 0→7 · Gelatin 0→6 · Antimicrobial 0→6
Landmark Nanostructured Titanium for Biomedical Applications · 258 cites
◆ Advancements555 · 30%
31%→31% share
▲1.0× share momentum1 median citations53% since 2021mostly methods-led
Robotic surgery advancement is intensifying — U.S. papers rose from 18 to 29, with Health care topics exploding from 2 to 24.
rising sub-themes (early→recent)
  • Health care2→24
  • MEDLINE1→21
  • Quality (philosophy)3→15
  • Robotic surgery18→29
  • Product (mathematics)5→16
Newly emergingClearance 0→6 · Wearable computer 0→6 · Single use 0→6
Landmark New Technology and Health Care Costs — The Case of Robot-Assisted Surgery · 962 cites
▼ Concerns582 · 32%
▼ 35%→31% share
▼0.9× share momentum1 median citations51% since 2021mostly position pieces
Patient-safety and MEDLINE concern papers are escalating — MEDLINE surged 1→36, Patient safety 19→32 in U.S. Concerns research.
rising sub-themes (early→recent)
  • MEDLINE1→36
  • Robotic surgery7→24
  • Patient safety19→32
  • Key (lock)6→19
  • Quality (philosophy)10→20
Newly emergingSystematic review 0→9 · Confidentiality 0→8 · Workflow 0→6
Landmark Current and emerging applications of 3D printing in medicine · 581 cites
RESEARCH HOTSPOTS · United States

Where medical devices is researched across United States

Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.

Boston116 · +0.15
Hot · Medical emergencyAdvancing · Biomedical engineeringOpportunity · ClearanceConcern · Health care
SF Bay Area70 · +0.06
Hot · Food and drug administrationAdvancing · Surgical robotOpportunity · Key (lock)Concern · Biomedical engineering
New York59 · +0.21
Hot · PaymentAdvancing · KinematicsOpportunity · MEDLINEConcern · Risk analysis (engineering)
Seattle40 · +0.25
Hot · Haptic technologyAdvancing · Computer visionOpportunity · CalibrationConcern · Risk analysis (engineering)
Los Angeles36 · +0.38
Hot · Mobile deviceAdvancing · Task (project management)Opportunity · Wireless
Chicago33 · +0.16
Hot · SurgeryAdvancing · Surgical robotOpportunity · MEDLINEConcern · Clinical trial
Philadelphia28 · +0.12
Hot · Wearable computerAdvancing · InteroperabilityOpportunity · Payment
San Diego27 · +0.36
Hot · SurgeryAdvancing · Task (project management)Opportunity · Robotic surgeryConcern · Adverse effect
Pittsburgh25 · +0.44
Hot · SoftwareAdvancing · Biocompatible materialOpportunity · Software deployment
Atlanta23 · +0.43
Hot · RobotAdvancing · Surgical robotOpportunity · Patient safety
PATENT SIGNAL · United States

Who's filing medical devices patents in the United States

United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.

666,693 filings8,000 assigneespeak 71776/yr2016–2025
filing momentum (YoY 2016–2025)
top patent filers
  • Covidien29351
  • Boston Scient Scimed24775
  • Medtronic22434
  • Becton Dickinson18269
  • Procter & Gamble16210
  • Ethicon ENDO Surgery13758
  • Kimberly Clark12462
  • Ethicon11769

Common questions

How many Medical Devices companies are there in United States?
Radar tracks 886 indexable Medical Devices companies headquartered in United States that meet our profile-completeness bar.
What is the total funding raised by Medical Devices companies in United States?
The Medical Devices companies in United States on this list have raised a combined $340.1M in disclosed equity funding across 9 funded companies.
Which is the highest-funded Medical Devices company in United States?
Paradigm Spine is the highest-funded Medical Devices company in United States, with $103.7M in disclosed equity funding.
How many Medical Devices companies in United States are funded?
9 of the 886 Medical Devices companies in United States on this list have disclosed at least one equity funding round.
How many Medical Devices unicorns are there in United States?
None of the Medical Devices companies in United States on this list currently has a disclosed valuation of $1B or more.
Who are the top investors in United States Medical Devices companies?
The most active investors in United States Medical Devices companies on this list include a range of venture and angel investors.
Rohit KhannaTrends & Stories

Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.

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