Best Nanotechnology Companies in United States
The 978 best Nanotechnology companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Novavax.
Ranking the top Nanotechnology companies across the United States by disclosed equity funding, this directory tracks 978 ventures carrying $15.1B in total disclosed capital, with one unicorn in the mix. The market context makes that funding look rational: the global nanotechnology sector was valued at roughly $1.8B in 2020 and is forecast to reach $33.6B by 2030 at a 34.3% CAGR, driven by demand for miniaturized devices and healthcare diagnostics. Sirnaomics leads our directory at $267M in disclosed funding, with Kala Pharmaceuticals close behind at $115M.
The validated filing data is where it gets interesting for you. Nine filers report a combined revenue pool of roughly $1.6B, but the median sits at just $4M, which tells you how top-heavy this sector really is. Mentor Graphics Corp alone filed $1.3B in revenue, 295 times that sector median, and Liquidia Corp posted $158M on 1031% YoY growth. So the floor is thin and the ceiling is stratospheric. Median revenue growth across filers ran at -28% YoY, a reminder that scale here is earned unevenly. Hot research themes, including nanotechnology's emerging role in Alzheimer's treatment and broader nanomedicine applications, suggest the next revenue inflection points are still forming. I'd watch the healthcare-adjacent names closely.
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Our analysis of 50 Nanotechnology companies
$6.5b in tracked funding; 78% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Nanotechnology companies in United States
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Market signals (1y) | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Novavax Developer of novel vaccines for the treatment of infectious diseases 83Product top 14%Patents top 17%Funding top 22%Innovation top 23% All 13 signals ▾Producttop 14% Patentstop 17% Fundingtop 22% Innovationtop 23% Partnerstop 26% Markettop 28% Moattop 29% Fin. healthtop 32% Globaltop 35% Growthtop 37% Newstop 40% Techtop 41% Talentbottom 48% Product: 4 distinct product lines · Company stage: Public Patents: 599 patents matched (strict assignee match) · 193 filings since 2022 vs 135 in 2017-21 rank vs industry peers · Fliar Intelligence Index 83/100 | $2.7B | 33 mo ago | 184 | John Jacobs President | DrupalApple iCloud MailMicrosoft 365+25 | 35 signals ▼38% Earnings · Regulatory · Acquisition | 599 patents Patents concentrated in chemistry & materials | 2 launchs · 2 partnerships |
| 2 | Sila Nanotechnologies 🦄 Provider of nanotech-based lithium-ion batteries for diversified applications 82Funding top 15%Patents top 17%Product top 18%Innovation top 22% All 11 signals ▾Fundingtop 15% Patentstop 17% Producttop 18% Innovationtop 22% Moattop 22% Talenttop 22% Growthtop 32% Markettop 39% Techtop 48% Globalbottom 47% Newsbottom 21% Funding: Raised $1.3B across 11 rounds · 11 rounds over 14 yrs (0.8/yr) Patents: 357 patents matched (strict assignee match) · 204 filings since 2022 vs 116 in 2017-21 rank vs industry peers · Fliar Intelligence Index 82/100 | $1.3B | 23 mo ago | 316 316 → 421 (+33%) · sector median +42% | Gleb Yushin Co-Founder & CTO | Craft CMSApple iCloud MailPHP+18 | — | 357 patents Patents concentrated in electrical & electronics | 1 expansion |
| 3 | 6K Provider of nanotechnology-based metal powders 60Funding top 15%Talent top 28%Moat top 31%Tech top 34% All 8 signals ▾Fundingtop 15% Talenttop 28% Moattop 31% Techtop 34% Growthtop 47% Marketbottom 41% Globalbottom 37% Newsbottom 21% Funding: Raised $300M across 17 rounds · 17 rounds over 12 yrs (1.4/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 60/100 | $300M | 22 mo ago | 62 62 → 153 (+147%) · sector median +42% | Awanish Raj Co-Founder & CTO | WordPress Block EditorElementorWordPress+35 | — | — | 1 partnership |
| 4 | Sirnaomics Developer of RNA based therapeutics for the treatment of cancer and fibrosis disease 80Patents top 14%Funding top 15%Innovation top 17%Growth top 28% All 9 signals ▾Patentstop 14% Fundingtop 15% Innovationtop 17% Growthtop 28% Moattop 35% Markettop 46% Talentbottom 49% Globalbottom 48% Newsbottom 21% Patents: 277 patents matched (strict assignee match) · 191 filings since 2022 vs 63 in 2017-21 Funding: Raised $267M across 14 rounds · 14 rounds over 19 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 80/100 | $267M | 9 mo ago | 88 | Patrick Lu President and CEO | — | — | 277 patents siRNA therapeutics and nanoparticle delivery systems for cancer and viral diseases | 1 launch |
| 5 | Forge Nano Manufacturer of atomic layer deposition equipment and related coated materials 67Funding top 18%Patents top 18%Product top 21%Innovation top 24% All 11 signals ▾Fundingtop 18% Patentstop 18% Producttop 21% Innovationtop 24% Moattop 28% Talenttop 34% Growthtop 43% Techtop 44% Globalbottom 42% Marketbottom 41% Newsbottom 38% Funding: Raised $162M across 14 rounds · 14 rounds over 11 yrs (1.3/yr) Patents: 72 patents matched (strict assignee match) · 49 filings since 2022 vs 22 in 2017-21 rank vs industry peers · Fliar Intelligence Index 67/100 | $162M | 13 mo ago | 65 65 → 124 (+91%) · sector median +42% | Paul Lichty Co-Founder & CEO | WordPressMySQLPHP+23 | 3 signals ▼50% Funding · IPO | 72 patents Advanced atomic layer deposition for high-performance energy storage and conversion components | — |
| 6 | Ashvattha Therapeutics Developer of nanomedicines for ophthalmology, neurology, and inflammatory diseases 45Funding top 23%Moat top 36%Talent top 38%Market bottom 41% All 6 signals ▾Fundingtop 23% Moattop 36% Talenttop 38% Marketbottom 41% Globalbottom 37% Newsbottom 22% Funding: Raised $130M across 8 rounds · 8 rounds over 10 yrs (0.8/yr) Moat: Editorial + unicorn rating 7/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 45/100 | $130M | 17 mo ago | 40 | Kannan Rangaramanujam Co-Founder & CTO | — | — | — | — |
| 7 | Kala Pharmaceuticals Developer of ophthalmic treatments based on its mucosal penetrating product platform 45Funding top 22%Product top 24%Talent top 33%News top 34% All 12 signals ▾Fundingtop 22% Producttop 24% Talenttop 33% Newstop 34% Moattop 35% Patentstop 37% Innovationtop 41% Techbottom 49% Marketbottom 42% Growthbottom 42% Globalbottom 40% Fin. healthbottom 36% Funding: Raised $115M across 14 rounds · 14 rounds over 17 yrs (0.8/yr) Product: 2 distinct product lines · Company stage: Public rank vs industry peers · Fliar Intelligence Index 45/100 | $115M | 3 mo ago | 34 34 → 80 (+135%) · sector median +42% | Justin Hanes Co-Founder | DrupalApple iCloud MailPHP+20 | 10 signals ▲25% Funding · Earnings · Leadership | 267 patents Mucosal and ocular drug delivery via nanoparticle and polymer-based pharmaceutical formulations | — |
| 8 | ZwitterCo Manufacturer of wastewater treatment systems using membrane technology 60Funding top 24%Product top 30%Innovation top 33%Moat top 37% All 11 signals ▾Fundingtop 24% Producttop 30% Innovationtop 33% Moattop 37% Techtop 38% Talenttop 38% Patentstop 39% Growthtop 40% Globalbottom 39% Marketbottom 38% Newsbottom 21% Funding: Raised $102M across 5 rounds · 5 rounds over 6 yrs (0.8/yr) Product: 8 distinct product lines · Company stage: Series B rank vs industry peers · Fliar Intelligence Index 60/100 | $102M | 23 mo ago | 57 57 → 86 (+51%) · sector median +42% | Christopher Drover Co-Founder & CTO | WordPressSentryMySQL+39 | — | 14 patents Patents concentrated in chemistry & materials | 1 launch |
| 9 | Molekule Manufacturer of air purification and humidification devices with filtration technology 50Funding top 28%Innovation top 29%Patents top 29%Product top 34% All 13 signals ▾Fundingtop 28% Innovationtop 29% Patentstop 29% Producttop 34% Moattop 38% Techtop 41% Growthtop 45% Customerstop 50% Talentbottom 49% Marketbottom 44% Globalbottom 40% Newsbottom 36% Fin. healthbottom 29% Funding: Raised $97.9M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) Innovation: 77 patents (top 23% of patent-holders) · 39 filings since 2022 vs 38 in 2017-21 rank vs industry peers · Fliar Intelligence Index 50/100 | $98M | 13 mo ago | 92 92 → 81 (-12%) · sector median +42% | Jason Dibona CEO | ShopifyApple iCloud MailMicrosoft 365+16 | — | 77 patents Indoor air purification using photocatalytic and UV-based filtration technologies | — |
| 10 | NanoH2O Developer of reverse osmosis membranes for water treatment 76Growth top 13%Funding top 24%Patents top 41%Market top 43% All 8 signals ▾Growthtop 13% Fundingtop 24% Patentstop 41% Markettop 43% Moattop 45% Innovationtop 46% Newsbottom 44% Globalbottom 42% Growth: Headcount 15 → 120 (+700%) across vintages · Fresh capital in last 24 mo Funding: Raised $89.9M across 8 rounds · 8 rounds over 19 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 76/100 | $90M | 6 mo ago | 120 | — | — | — | 95 patents Enhanced thin‑film composite membrane technology for high‑flux water desalination | — |
| 11 | actnano Provider of nanocoatings for diversified applications 62Patents top 24%Moat top 25%Funding top 26%Innovation top 27% All 10 signals ▾Patentstop 24% Moattop 25% Fundingtop 26% Innovationtop 27% Growthtop 31% Techtop 49% Marketbottom 43% Newsbottom 42% Globalbottom 42% Talentbottom 40% Patents: 54 patents matched (strict assignee match) · 49 filings since 2022 vs 5 in 2017-21 Moat: Editorial + unicorn rating 7/10 · IP moat: 54 patents rank vs industry peers · Fliar Intelligence Index 62/100 | $82M | 20 mo ago | 45 45 → 98 (+118%) · sector median +42% | Taymur Ahmad Founder and CEO | WordPressMySQLPHP+26 | — | 54 patents Low-friction, anti-fog zwitterionic hydrogel and polymer coating technologies. | — |
| 12 | Cresilon Developer of hemostatic products for wound care 60Funding top 22%Growth top 32%Moat top 32%Product top 35% All 10 signals ▾Fundingtop 22% Growthtop 32% Moattop 32% Producttop 35% Techtop 37% Patentstop 42% Innovationtop 48% Marketbottom 46% Globalbottom 36% Newsbottom 18% Funding: Raised $81.7M across 8 rounds · 8 rounds over 10 yrs (0.8/yr) Growth: Headcount 53 → 73 (+38%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 60/100 | $82M | 1 mo ago | 73 | — | WordPressApple iCloud MailMicrosoft 365+36 | — | 40 patents Hemostatic polymer adhesives and delivery devices for rapid surgical bleeding control | — |
| 13 | Nano C Manufacturer of carbon nanostructures 50Patents top 18%Funding top 24%Innovation top 26%Moat top 26% All 9 signals ▾Patentstop 18% Fundingtop 24% Innovationtop 26% Moattop 26% Growthtop 47% Talentbottom 49% Techbottom 44% Globalbottom 38% Marketbottom 32% Patents: 248 patents matched (strict assignee match) · 75 filings since 2022 vs 51 in 2017-21 Funding: Raised $68.2M across 23 rounds · 23 rounds over 13 yrs (1.8/yr) rank vs industry peers · Fliar Intelligence Index 50/100 | $68M | 10 mo ago | 32 32 → 32 (+0%) · sector median +42% | Jack Howard Founder | WordPressMySQLPHP+22 | — | 248 patents Nanostructured conductive inks and transparent films for optoelectronic devices. | 2 partnerships |
| 14 | Nuo Therapeutics Developer of regenerative products for wound care 53Growth top 11%Funding top 24%Talent top 45%Fin. health top 50% All 9 signals ▾Growthtop 11% Fundingtop 24% Talenttop 45% Fin. healthtop 50% Moatbottom 38% Globalbottom 37% Marketbottom 33% Techbottom 30% Newsbottom 21% Growth: Revenue +143% YoY · Fresh capital in last 24 mo Funding: Raised $64.6M across 18 rounds · 18 rounds over 16 yrs (1.1/yr) rank vs industry peers · Fliar Intelligence Index 53/100 | $65M | 10 mo ago | 10 10 → 19 (+90%) · sector median +42% | David Jorden CEO & Director | — | — | — | — |
| 15 | Clene Nanomedicine Developer of therapeutics for the treatment of neurodegenerative diseases 29Funding top 29%Patents top 36%Tech top 41%Innovation top 47% All 10 signals ▾Fundingtop 29% Patentstop 36% Techtop 41% Innovationtop 47% Growthbottom 49% Moatbottom 44% Globalbottom 42% Marketbottom 32% Newsbottom 32% Fin. healthbottom 15% Funding: Raised $59.1M across 8 rounds · 8 rounds over 7 yrs (1.1/yr) Patents: 78 patents matched (strict assignee match) · 10 filings since 2022 vs 60 in 2017-21 rank vs industry peers · Fliar Intelligence Index 29/100 | $59M | 20 mo ago | 99 | — | DrupalPHPMediaElement.js+28 | — | 78 patents Continuous nanomaterial synthesis and gold nanocrystal production for neuroregenerative therapies | — |
| 16 | Genedit Developer of drug delivery system for genetic medicines 53Funding top 28%Talent top 28%Product top 30%Patents top 31% All 9 signals ▾Fundingtop 28% Talenttop 28% Producttop 30% Patentstop 31% Innovationtop 34% Moattop 36% Marketbottom 41% Techbottom 40% Globalbottom 40% Funding: Raised $58.5M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) Talent: Analyst team rating 4/5 rank vs industry peers · Fliar Intelligence Index 53/100 | $58M | 18 mo ago | 39 39 → 64 (+64%) · sector median +42% | — | — | — | 73 patents Non‑viral cationic polymers for biomolecule delivery and engineered Cpf1 guide RNAs | — |
| 17 | American Gene Developer of lentivirus therapies for the treatment of cancer and other chronic human diseases 55Funding top 24%Patents top 31%Moat top 35%Talent top 35% All 11 signals ▾Fundingtop 24% Patentstop 31% Moattop 35% Talenttop 35% Innovationtop 37% Growthtop 40% Producttop 40% Techtop 46% Marketbottom 36% Globalbottom 36% Newsbottom 22% Funding: Raised $52.8M across 10 rounds · 10 rounds over 13 yrs (0.8/yr) Patents: 228 patents matched (strict assignee match) · 90 filings since 2022 vs 138 in 2017-21 rank vs industry peers · Fliar Intelligence Index 55/100 | $53M | 7 mo ago | 31 | Jeff Galvin Chief Executive Officer | WordPressMySQLPHP+34 | — | 228 patents Non-integrating viral vectors for gene delivery and HIV immunotherapy, plus gamma‑delta T‑cell activation | — |
| 18 | Nanoramic Provider of nanotech based electrode materials for supercapacitors 72Growth top 17%Funding top 19%Patents top 26%Moat top 28% All 10 signals ▾Growthtop 17% Fundingtop 19% Patentstop 26% Moattop 28% Talenttop 28% Innovationtop 31% Newstop 34% Marketbottom 47% Globalbottom 40% Techbottom 33% Growth: Headcount 39 → 66 (+69%) across vintages · Fresh capital in last 24 mo Funding: Raised $49.6M across 24 rounds · 24 rounds over 16 yrs (1.5/yr) rank vs industry peers · Fliar Intelligence Index 72/100 | $50M | 7 mo ago | 66 66 → 50 (-24%) · sector median +42% | John Cooley Founder & CEO | — | 4 signals ▲300% Funding | 36 patents Advanced electrode materials and hydrophilic binders for high-performance rechargeable batteries | — |
| 19 | Aether Bio Developer of high-throughput robotic laboratories 21Funding top 28%Moat top 35%Talent bottom 49%Global bottom 39% All 6 signals ▾Fundingtop 28% Moattop 35% Talentbottom 49% Globalbottom 39% Marketbottom 34% Techbottom 21% Funding: Raised $49.0M across 2 rounds · 2 rounds over 3 yrs (0.7/yr) Moat: Editorial + unicorn rating 4/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 21/100 | $49M | 6 mo ago | 17 | Pavle Jeremic Co-Founder & CEO | — | — | — | — |
| 20 | Pixelligent Manufacturer of high refractive index nanocrystal formulations for electronics applications 62Funding top 25%Innovation top 26%Patents top 26%Moat top 28% All 11 signals ▾Fundingtop 25% Innovationtop 26% Patentstop 26% Moattop 28% Producttop 30% Growthtop 32% Techtop 36% Talentbottom 49% Globalbottom 42% Marketbottom 31% Newsbottom 21% Funding: Raised $48.2M across 33 rounds · 33 rounds over 21 yrs (1.6/yr) Innovation: 71 patents (top 25% of patent-holders) · 3 product lines rank vs industry peers · Fliar Intelligence Index 62/100 | $48M | 13 mo ago | 29 29 → 45 (+55%) · sector median +42% | Craig Bandes President & CEO | WordPressMySQLMariaDB+36 | — | 71 patents Nanocrystal synthesis, high‑index silicone nanocomposites, and light‑extraction structures for optical displays | — |
| 21 | NanoViricides Targeted antiviral therapeutics 14Funding top 26%Moat top 48%Growth bottom 40%News bottom 35% All 7 signals ▾Fundingtop 26% Moattop 48% Growthbottom 40% Newsbottom 35% Globalbottom 30% Marketbottom 29% Techbottom 24% Funding: Raised $47.0M across 7 rounds · 7 rounds over 15 yrs (0.5/yr) Moat: Editorial + unicorn rating 5/10 · 10 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 14/100 | $47M | 7 mo ago | 17 | — | RequireJSHSTSOpen Graph | — | — | — |
| 22 | NanoTech Materials Provider of roof coating, fireproofing, insulation, and custom formulation 48Tech top 26%Funding top 35%Talent top 38%News top 40% All 10 signals ▾Techtop 26% Fundingtop 35% Talenttop 38% Newstop 40% Growthtop 45% Producttop 46% Innovationbottom 46% Moatbottom 38% Marketbottom 36% Globalbottom 32% Tech: 41 technologies across 6/8 capability areas · Cloud: Cloudflare Funding: Raised $43.7M across 3 rounds · 3 rounds over 6 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $44M | 2 mo ago | — | Hani Taan Chief Technology Officer & Co-Founder | Node.jsNextAuth.jsTailwind CSS+21 | 3 signals Funding · New product | — | — |
| 23 | Swift Solar Provider of flexible perovskite solar cells 69Growth top 17%Innovation top 20%Patents top 23%Talent top 25% All 10 signals ▾Growthtop 17% Innovationtop 20% Patentstop 23% Talenttop 25% Fundingtop 29% Newstop 30% Moattop 32% Techbottom 42% Globalbottom 40% Marketbottom 30% Growth: 5 acquisition/expansion moves in 24 mo · Fresh capital in last 24 mo Innovation: 63 patents (top 27% of patent-holders) · 50 filings since 2022 vs 13 in 2017-21 rank vs industry peers · Fliar Intelligence Index 69/100 | $42M | 13 mo ago | 19 | Tomas Leijtens Cto | WebflowApple iCloud MailGoogle Workspace+11 | 8 signals Acquisition · Announcements | 63 patents Integrating robust interconnects and moisture barriers for perovskite‑silicon tandem solar modules | 1 job opening |
| 24 | Electronic Bio Provider of nanotech-based DNA sequencing solutions 10Funding top 37%Talent bottom 45%Global bottom 29%Market bottom 24% All 5 signals ▾Fundingtop 37% Talentbottom 45% Globalbottom 29% Marketbottom 24% Techbottom 15% Funding: Raised $40.7M across 49 rounds · 49 rounds over 19 yrs (2.6/yr) Talent: 1 named leader on record rank vs industry peers · Fliar Intelligence Index 10/100 | $41M | 12 mo ago | 15 | Eric Ervin President and CEO | — | — | — | — |
| 25 | Imbed Biosciences Provider of nanotech-based wound care products 48Growth top 32%Funding top 37%Talent top 38%Moat top 39% All 7 signals ▾Growthtop 32% Fundingtop 37% Talenttop 38% Moattop 39% Techtop 44% Marketbottom 33% Globalbottom 32% Growth: Headcount 24 → 35 (+46%) across vintages · Fresh capital in last 24 mo Funding: Raised $34.3M across 18 rounds · 18 rounds over 16 yrs (1.1/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $34M | 4 mo ago | 35 35 → 40 (+14%) · sector median +42% | Michael Schurr Co-Founder & Chief Medical Officer | WordPress Block EditorCart FunctionalityWordPress+30 | — | — | — |
| 26 | Chasm Technologies Manufacturer of carbon nanotechnology materials for various applications and industries 29Funding top 31%Moat top 39%Tech top 50%Talent bottom 49% All 9 signals ▾Fundingtop 31% Moattop 39% Techtop 50% Talentbottom 49% Growthbottom 41% Globalbottom 37% Partnersbottom 35% Newsbottom 34% Marketbottom 33% Funding: Raised $33.7M across 7 rounds · 7 rounds over 10 yrs (0.7/yr) Moat: Editorial + unicorn rating 7/10 · 9 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 29/100 | $34M | 21 mo ago | 28 28 → 29 (+4%) · sector median +42% | David Arthur CEO / Co-Founder | HubSpot CMS HubAnimate.cssMicrosoft Advertising+27 | — | — | — |
| 27 | Oceanit Provider of nanocomposites for diversified purposes 55Innovation top 23%Funding top 35%Growth top 35%Tech top 42% All 8 signals ▾Innovationtop 23% Fundingtop 35% Growthtop 35% Techtop 42% Producttop 46% Talentbottom 49% Marketbottom 29% Globalbottom 29% Innovation: 5 product lines · Deep-tech classification: Tech Hardware Funding: Raised $31.4M across 21 rounds · 21 rounds over 18 yrs (1.2/yr) rank vs industry peers · Fliar Intelligence Index 55/100 | $31M | 12 mo ago | — | Patrick Sullivan Founder | WordPressApple iCloud MailMySQL+28 | — | — | 1 job opening · 1 internship · 1 award |
| 28 | NanoSonic Nanomaterial innovator specializing in sensors, additive manufacturing, and polymer design 22Funding top 35%Talent top 39%AI top 45%Market bottom 30% All 6 signals ▾Fundingtop 35% Talenttop 39% AItop 45% Marketbottom 30% Globalbottom 29% Techbottom 15% Funding: Raised $30.5M across 31 rounds · 31 rounds over 20 yrs (1.6/yr) Talent: Analyst team rating 4/5 · 1 named leader on record rank vs industry peers · Fliar Intelligence Index 22/100 | $31M | 6 mo ago | 25 | Richard Claus Founder & CEO | — | — | — | — |
| 29 | Carbitex Provider of carbon-fibre induced materials for the fashion industry 48Product top 25%Funding top 32%Moat top 32%Innovation top 33% All 11 signals ▾Producttop 25% Fundingtop 32% Moattop 32% Innovationtop 33% Patentstop 33% Growthtop 40% Talentbottom 49% Techbottom 42% Newsbottom 37% Marketbottom 35% Globalbottom 33% Product: 7 distinct product lines · Company stage: Series C Funding: Raised $28.0M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $28M | 20 mo ago | 43 43 → 26 (-40%) · sector median +42% | Junus Khan Founder & President | Webflow EcommerceWebflowcore-js+13 | — | 43 patents Anisotropic fiber‑reinforced composites for puncture‑resistant footwear inserts | — |
| 30 | Direct Electron Developer of cameras for electron microscopy 57Innovation top 20%Growth top 35%Tech top 41%Funding top 42% All 8 signals ▾Innovationtop 20% Growthtop 35% Techtop 41% Fundingtop 42% Producttop 46% Talentbottom 45% Globalbottom 29% Marketbottom 23% Innovation: 11 product lines Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 57/100 | $25M | 12 mo ago | 13 | Rob Bilhorn Founder & President | WordPressMySQLPHP+34 | — | — | 1 launch |
| 31 | Mattiq Developer of an experimentation platform for accelerating materials discovery and design 53AI top 18%Moat top 31%Patents top 32%Innovation top 34% All 9 signals ▾AItop 18% Moattop 31% Patentstop 32% Innovationtop 34% Talenttop 38% Fundingtop 43% Techbottom 48% Globalbottom 35% Marketbottom 28% AI: Classified as an AI company · Holds AI/ML patents (G06N-family CPC) Moat: Editorial + unicorn rating 7/10 · IP moat: 16 patents rank vs industry peers · Fliar Intelligence Index 53/100 | $24M | 18 mo ago | 19 | Andrey Ivankin Co-Founder & Chief Technology Officer | WordPressApple iCloud MailGoogle Workspace+25 | — | 16 patents AI-driven design of functional materials and mixed‑metal electrocatalysts for energy applications | — |
| 32 | Applied Nanotech Develops and manufactures nano materials 45Product top 14%Funding top 31%Innovation top 34%Patents top 35% All 11 signals ▾Producttop 14% Fundingtop 31% Innovationtop 34% Patentstop 35% Moattop 35% Growthtop 44% Talentbottom 45% Fin. healthbottom 41% Marketbottom 38% Globalbottom 37% Techbottom 24% Product: 12 distinct product lines · Company stage: Public Funding: Raised $22.5M across 36 rounds · 36 rounds over 22 yrs (1.6/yr) rank vs industry peers · Fliar Intelligence Index 45/100 | $22M | 13 mo ago | 19 | Richard Fink CEO & President | — | — | 279 patents Enables low-cost copper conductive inks for printed circuit and flexible electronics | — |
| 33 | Sporian Microsystems Sensors, MEMS technologies & packaging solutions provider 29Innovation top 40%Funding top 40%Patents top 40%Moat top 45% All 7 signals ▾Innovationtop 40% Fundingtop 40% Patentstop 40% Moattop 45% Talentbottom 49% Globalbottom 33% Marketbottom 28% Innovation: 13 patents (top 61% of patent-holders) · 6 filings since 2022 vs 3 in 2017-21 Funding: Raised $20.9M across 23 rounds · 23 rounds over 6 yrs (3.8/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $21M | 13 mo ago | 15 | Brian Schaible President/CEO | — | — | 13 patents High‑temperature, corrosive‑fluid pressure and flow sensing with capacitive shielding technology | — |
| 34 | UbiQD Developer of low-cost quantum dots for industrial applications 45Funding top 26%Patents top 29%Innovation top 32%Moat top 32% All 10 signals ▾Fundingtop 26% Patentstop 29% Innovationtop 32% Moattop 32% Newstop 39% Talentbottom 49% Techbottom 48% Globalbottom 40% Partnersbottom 35% Marketbottom 31% Funding: Raised $18.4M across 15 rounds · 15 rounds over 10 yrs (1.5/yr) Patents: 65 patents matched (strict assignee match) · 31 filings since 2022 vs 33 in 2017-21 rank vs industry peers · Fliar Intelligence Index 45/100 | $18M | 4 mo ago | 27 | Hunter McDaniel Founder & CEO | WebflowreCAPTCHAHSTS+10 | 3 signals ▲200% Funding · Contracts | 65 patents Patents concentrated in chemistry & materials | 1 launch · 3 expansions |
| 35 | Therapyxinc Innovating microparticulate immune therapeutics for cancer, infectious disease, and inflammatory disorders 14Innovation top 43%Funding top 44%Product bottom 44%Global bottom 32% All 6 signals ▾Innovationtop 43% Fundingtop 44% Productbottom 44% Globalbottom 32% Techbottom 25% Marketbottom 19% Innovation: 2 product lines Funding: Raised $17.7M across 5 rounds · 5 rounds over 18 yrs (0.3/yr) rank vs industry peers · Fliar Intelligence Index 14/100 | $18M | 14 mo ago | 11 | — | — | — | — | — |
| 36 | NovaSolix Developer of rectenna-based solar technology for various applications and sectors 32Moat top 25%Funding top 33%Talent top 34%Patents top 41% All 7 signals ▾Moattop 25% Fundingtop 33% Talenttop 34% Patentstop 41% Innovationtop 47% Globalbottom 33% Marketbottom 25% Moat: Editorial + unicorn rating 6/10 · IP moat: 42 patents Funding: Raised $16.1M across 3 rounds · 3 rounds over 6 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 32/100 | $16M | 2 mo ago | 12 | Bob Cousins Co-Founder | — | — | 42 patents Solar-powered antenna arrays and low‑power semi‑reflective display technologies | 3 launchs · 2 partnerships |
| 37 | NaNotics Developer of nanomedical platform for treating major human and animal diseases 32Moat top 25%Patents top 33%Funding top 38%Talent top 38% All 7 signals ▾Moattop 25% Patentstop 33% Fundingtop 38% Talenttop 38% Innovationtop 44% Globalbottom 43% Marketbottom 23% Moat: Editorial + unicorn rating 7/10 · IP moat: 59 patents Patents: 59 patents matched (strict assignee match) · 26 filings since 2022 vs 33 in 2017-21 rank vs industry peers · Fliar Intelligence Index 32/100 | $10M | 10 mo ago | 9 | John Dodgson Co-Founder & CTO | — | — | 59 patents Therapeutic biomolecule inhibition and nucleic‑acid‑based scavenger particle platforms | — |
| 38 | Zyl Therapeutics Developer of hydrogel-derived nanoparticle system for topical applications 19Funding top 35%Talent top 35%Global bottom 29%Market bottom 21% All 4 signals ▾Fundingtop 35% Talenttop 35% Globalbottom 29% Marketbottom 21% Funding: Raised $9.4M across 7 rounds · 7 rounds over 8 yrs (0.9/yr) Talent: Analyst team rating 5/5 · 1 named leader on record rank vs industry peers · Fliar Intelligence Index 19/100 | $9M | 16 mo ago | 7 | Scott Pancoast CEO and Founder (and Board Member) | — | — | — | — |
| 39 | Electron Optica Provider of solutions for electron microscopy and electron lithography 37Funding top 44%Talent bottom 45%Global bottom 29% All 3 signals ▾Fundingtop 44% Talentbottom 45% Globalbottom 29% Funding: Raised $9.3M across 8 rounds · 8 rounds over 15 yrs (0.5/yr) Talent: 1 named leader on record rank vs industry peers · Fliar Intelligence Index 37/100 | $9M | 14 mo ago | — | Marian Mankos Founder & CEO | — | — | — | — |
| 40 | Materic Provider of diversified advanced materials 9Tech top 42%Funding bottom 46%Global bottom 29%Market bottom 15% All 4 signals ▾Techtop 42% Fundingbottom 46% Globalbottom 29% Marketbottom 15% Tech: 37 technologies across 5/8 capability areas · Cloud: Cloudflare Funding: Raised $9.2M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 9/100 | $9M | 13 mo ago | 2 | — | WordPress Block EditorCart FunctionalityWooCommerce+34 | — | — | — |
| 41 | Immix Biopharma Developer of therapeutics for amyloidosis, autoimmune diseases, and oncology indications 53Product top 14%News top 24%Growth top 32%Funding top 34% All 12 signals ▾Producttop 14% Newstop 24% Growthtop 32% Fundingtop 34% Innovationtop 39% Patentstop 41% Moattop 45% Techtop 47% Fin. healthtop 49% Talentbottom 49% Marketbottom 38% Globalbottom 36% Product: 5 distinct product lines · Company stage: Public News: 5 BI events in 12 mo (of 16 tracked, 7 types) · +150% YoY rank vs industry peers · Fliar Intelligence Index 53/100 | $9M | 9 mo ago | 11 | Ilya Rachman Co-Founder & CEO | WordPressApple iCloud MailMicrosoft 365+26 | 5 signals ▲150% Funding · Earnings · Capital raise | 25 patents Targeted nanoparticle delivery of therapeutic agents for cancer and inflammatory diseases | — |
| 42 | Adámas Nanodiamond innovator for quantum sensing, imaging, and industrial applications 16Tech top 33%Funding top 41%Global bottom 29%Market bottom 18% All 4 signals ▾Techtop 33% Fundingtop 41% Globalbottom 29% Marketbottom 18% Tech: 34 technologies across 6/8 capability areas · Cloud: Amazon S3, Amazon Web Services Funding: Raised $8.8M across 10 rounds · 10 rounds over 12 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 16/100 | $9M | 12 mo ago | 3 | — | Cart FunctionalitySquarespace CommerceSquarespace+15 | — | — | — |
| 43 | Sylvatex Developer of advanced materials for energy, industrial, and strategic applications 27Moat top 38%Funding top 40%Patents top 44%Innovation top 46% All 10 signals ▾Moattop 38% Fundingtop 40% Patentstop 44% Innovationtop 46% Producttop 46% Talentbottom 49% Techbottom 46% Globalbottom 37% Marketbottom 26% Newsbottom 21% Moat: Editorial + unicorn rating 4/10 · IP moat: 23 patents Funding: Raised $8.4M across 6 rounds · 6 rounds over 15 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 27/100 | $8M | 13 mo ago | 16 16 → 17 (+6%) · sector median +42% | Virginia Klausmeier President & CEO | WordPressMySQLPHP+22 | — | 23 patents Lithium‑ion battery cathode material synthesis and nanostructured carbon‑coated composites | 1 partnership |
| 44 | Endomimetics Developer of bio-nanometrics coating technology 14Funding top 38%Moat top 45%Product top 46%Talent bottom 49% All 9 signals ▾Fundingtop 38% Moattop 45% Producttop 46% Talentbottom 49% Innovationbottom 42% Patentsbottom 37% Techbottom 31% Globalbottom 31% Marketbottom 21% Funding: Raised $8.4M across 8 rounds · 8 rounds over 4 yrs (2.0/yr) Moat: Editorial + unicorn rating 4/10 · IP moat: 2 patents rank vs industry peers · Fliar Intelligence Index 14/100 | $8M | 10 mo ago | 7 | Joseph Garner Chief Executive Officer | — | — | 2 patents Peptide amphiphile therapeutics and biomaterial drug delivery systems | — |
| 45 | Signa Blok Developer of peptide therapeutics targeting receptor signaling 32Funding top 42%Innovation top 43%Product bottom 44%Market bottom 37% All 5 signals ▾Fundingtop 42% Innovationtop 43% Productbottom 44% Marketbottom 37% Globalbottom 29% Funding: Raised $7.3M across 15 rounds · 15 rounds over 14 yrs (1.1/yr) Innovation: 2 product lines rank vs industry peers · Fliar Intelligence Index 32/100 | $7M | 14 mo ago | — | — | — | — | — | — |
| 46 | Bnnt Materials Leading producer of Boron Nitride Nanotubes (BNNT) for advanced nanotechnology 19Innovation top 34%Product top 36%Talent bottom 49%Funding bottom 43% All 7 signals ▾Innovationtop 34% Producttop 36% Talentbottom 49% Fundingbottom 43% Marketbottom 26% Globalbottom 25% Techbottom 16% Innovation: 12 product lines Product: 12 distinct product lines · Company stage: Series A rank vs industry peers · Fliar Intelligence Index 19/100 | $6M | 6 mo ago | 12 | Roy Whitney President & CEO | — | — | — | — |
| 47 | Avisi Technologies Developer of nano-materials 21News top 34%Talent top 41%Funding top 42%Moat top 47% All 8 signals ▾Newstop 34% Talenttop 41% Fundingtop 42% Moattop 47% Patentsbottom 42% Globalbottom 39% Innovationbottom 35% Marketbottom 30% News: 4 BI events in 12 mo (of 8 tracked, 1 types) · Top themes: Funding Talent: Analyst team rating 4/5 · 1 named leader on record rank vs industry peers · Fliar Intelligence Index 21/100 | $5M | 3 mo ago | 15 | Rui Jiang Co-Founder & CEO | — | 4 signals Funding | 4 patents Ophthalmic therapeutic devices for delivering/tuning eye disease treatments | 1 award |
| 48 | Phoreus Biotech Provider of a nano-delivery platform for genetic vaccines and therapeutics 14Talent top 38%Tech top 50%Funding bottom 48%Global bottom 30% All 5 signals ▾Talenttop 38% Techtop 50% Fundingbottom 48% Globalbottom 30% Marketbottom 18% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Tech: 29 technologies across 3/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 14/100 | $4M | 7 mo ago | 6 | Randall Tosh Founder & CEO | WordPressMySQLPHP+26 | — | — | — |
| 49 | C-Crete Cement-free concrete revolutionizing construction with ultra-low carbon footprint and high performance 10Growth top 45%Funding bottom 41%Tech bottom 30%Global bottom 25% All 5 signals ▾Growthtop 45% Fundingbottom 41% Techbottom 30% Globalbottom 25% Marketbottom 19% Growth: Web rank 10,000,000 → 50,000,000 YoY · Fresh capital in last 24 mo Funding: Raised $4.2M across 7 rounds · 7 rounds over 16 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 10/100 | $4M | 12 mo ago | 5 | — | WordPress Block EditorWordPressMySQL+10 | — | — | 1 award |
| 50 | DexMat Manufacturer of advanced carbon material for aerospace, automotive, and energy industries 32Growth top 35%Funding top 41%News top 45%Moat top 48% All 8 signals ▾Growthtop 35% Fundingtop 41% Newstop 45% Moattop 48% Techtop 49% Talentbottom 49% Globalbottom 37% Marketbottom 21% Growth: Fresh capital in last 24 mo Funding: Raised $3.0M across 6 rounds · 6 rounds over 3 yrs (2.0/yr) rank vs industry peers · Fliar Intelligence Index 32/100 | $3M | 7 mo ago | 4 | Bryan Hassin CEO | Cart FunctionalityWooCommerceWordPress+28 | — | — | 1 job opening · 1 partnership · 1 award |
Top 12 Nanotechnology companies in United States
#1
Series B · New York City, New York · founded 2010 · 73 employees$81.7Mraised▾
Developer of hemostatic products for wound care. The company offers VETIGEL Hemostatic Gel(a prescription hemostatic gel kit for animal use only. It can stop moderate to severe bleeds in animals), and TRAUMAGEL a hemostatic device for temporary use to control external traumatic bleeding not amenable to tourniquet application.
- Apr 2026Series B$5M
- Nov 2025Series B$6.7M
- Apr 2024Series B$25M
- Aug 2023Series A$17.2M
#2
Public · Waltham, Massachusetts · founded 2009 · 34 employees$115.5Mraised▾
Developer of ophthalmic treatments based on its mucosal penetrating product platform. It offers therapies for severe ophthalmic diseases. The company’s MPP drug delivery technology platform allows therapeutic agents to pass through the mucus layer(tears) of the ocular surface, facilitating penetration into deeper tissues of the eye, including the aqueous humor and retina. Its solutions are used in treating severe ophthalmic diseases, including ocular inflammation and wet age-related macular degeneration. Its drug pipeline includes KPI-121, an ophthalmic MPP suspension in development for the treatment of post-surgical inflammation , dry eye , meibomian gland disease. Also developing MPP based topical drugs for AMD (orphan indication). It has applications in the treatment of both anterior and posterior chamber eye diseases.
- Mar 2026Post IPO$1.8M
- Jan 2026Post IPO$2.3M
- Dec 2024Post IPO$10.8M
- Jun 2024Post IPO$12.5M
#3
Series A · Houston, Texas · founded 2019$43.7Mraised▾
Provider of roof coating, fireproofing, insulation, and custom formulation
- Apr 2026Series A$29.4M
- Jul 2023Series A$9.3M
- Dec 2020Seed$5M
#4
Public · Gaithersburg, Maryland · founded 2007 · 88 employees$267Mraised▾
Developer of RNA-based therapeutics for the treatment of cancer and fibrosis disease. The company has proprietary delivery technologies, a polypeptide nanoparticle RNAi platform and GalNAc RNAi platform, GalAhead, to develop drug candidate pipeline which include STP122G for cardiovascular disease treatment. It also, develops pipeline of drugs for cancers, skin conditions, fibrosis-related diseases, antiviral and cardiometabolic diseases, and medical aesthetics.
- Sep 2025Post IPO$17.7M
- Jul 2021Series E$105M
- Oct 2020Series D$105M
- Jul 2019Series C$25M
#5
Acquired · Los Angeles, California · founded 2005 · 120 employees$89.9Mraised▾
Developer of reverse osmosis membranes for water treatment. The company developed thin-film nanocomposite QuantumFlux membranes for seawater and brackish water desalination, as well as wastewater reclamation.
- Dec 2025Series D—
- Apr 2012Conventional Debt$20.5M
- Apr 2012Series C$40M
- Dec 2011Series C$14.9M
#6
Series C · Madison, Wisconsin · founded 2010 · 35 employees$34.3Mraised▾
Provider of nanotech-based wound care products. The company has developed technologies for embedding bioactive molecules in wound dressings and surgical implants. The products are based on the Microlyte Matrix technology platform. The company also offers antibacterial, anti-biofilm, and analgesic wound dressings.
- Jan 2026Series C—
- Jan 2024Convertible Debt$10M
- Dec 2023Series B$3.5M
- May 2023Series B$2.5M
#7
Series C · Newark, California · founded 2015 · 12 employees$16.1Mraised▾
Developer of rectenna-based solar technology for various applications and sectors. The technology aims to improve efficiency and lower the cost of solar energy. It focuses on harvesting the full solar spectrum with nanoscale antenna arrays. These arrays translate solar radiation directly into electrical work output. The technology targets sectors like AI, data centers, electric vehicles, aerospace, and electronics.
- Apr 2026Series C$3.9M
- Nov 2024Series B$150K
- Oct 2022Series B$16.1M
- Dec 2020Series A—
#8
Series E · Boston, Massachusetts · founded 2009 · 66 employees$49.6Mraised▾
Provider of nanotech based electrode materials for supercapacitors. It offers nanotech-enabled electrodes, ultracapacitors, and thermal interface gap filler pads for electric vehicle batteries. Its features include low cost, high cell-level energy density, fast charging performance, thermal interface gap filler and roll-to-roll coating, and calendering equipment.
- Nov 2025Series E$54M
- Sep 2025Series D—
- Apr 2025Grant (prize money)$47.5M
- Jan 2025Grant (prize money)$47.5M
#9
Series B · Rockville, Maryland · founded 2008 · 31 employees$52.8Mraised▾
Developer of lentivirus therapies for the treatment of cancer and other chronic human diseases. The company has developed drugs using its delivery platform. The product pipeline includes a liver cancer therapeutic lentivirus and an AIDS therapeutic lentivirus, as well as Parkinson’s disease therapeutic lentivirus, and a familial dysautonomia therapeutic lentivirus.
- Nov 2025Series B$310K
- Apr 2022Series B$50M
- Nov 2015Series A$1.2M
- Sep 2015Grant (prize money)$232.2K
#10
Public · West Haven, Connecticut · founded 2005 · 17 employees$47Mraised▾
NanoViricides discovers, develops and commercializes therapeutics to treat viral infections. Nanoviricide is an antiviral agent based on the TheraCour polymeric micelle technology. This is a biomimetic platform technology has enabled the Company to rapidly develop highly effective drug candidates against a number of viral diseases. Currently developing drugs against five diseases: FluCide, a single drug against all influenzas including pandemic viruses, bird flu (H5N1), and highly pathogenic strains; HIVCide, which was found to be so effective in SCID-hu mouse model studies that it is widely believed that it could result in a “functional cure” of HIV/AIDS; HerpeCide for oral and genital herpes; DengueCide, a single drug to combat all dengue virus types; and a broad-spectrum antiviral for infections of the external eye.
- Nov 2025Post IPO$6M
- Feb 2019Post IPO$2.5M
- Jan 2014Post IPO$20M
- Feb 2013Post IPO$6M
#11
Series B · Los Alamos, New Mexico · founded 2014 · 27 employees$18.4Mraised▾
Developer of low-cost quantum dots for industrial applications. The company produces low-toxicity quantum dots, which are being used to develop semi-transparent windows that convert the energy-passive facades of buildings into distributed energy generation units, while simultaneously reducing the heat gain of the building. The technology works by tinting a window with a fluorophore that absorbs sunlight and subsequently luminesces monochromatic light. This light is guided through the window to the edge where a small PV device converts the light into electricity. The LSC is semi-transparent, and filters visible light neutrally, so as not to impart unnatural colour to the transmitted light.
- Jan 2026Series B$8.3M
- Nov 2025Conventional Debt$6M
- Apr 2025Series B$20M
- Jul 2024Grant (prize money)$175K
#12
Series A · Menlo Park, California · founded 2017 · 17 employees$49Mraised▾
Developer of high-throughput robotic laboratories. It developed high-throughput robotic laboratories and customized machine-learning solutions. Its solution can help to produce an enzyme, chemicals, and biological materials.
- Dec 2025Series A$15M
- Aug 2023Series A$49M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Nanotechnology coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Nanomaterials is moving in the United States
A read on the academic research around Nanomaterials — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 7,242 United States-affiliated papers.
- Massachusetts Institute of Technology149
- Purdue University West Lafayette140
- Argonne National Laboratory125
- Stanford University124
- Lawrence Berkeley National Laboratory114
- Nanoparticle166→713
- Quantum dot32→282
- Catalysis58→282
- Quantum3→158
- Nanocomposite38→186
- Nanoparticle166→683
- Nanocomposite24→211
- Quantum dot30→162
- Catalysis46→170
- Photocatalysis17→137
- Quantum dot11→28
- Catalysis4→17
- Nanoparticle57→68
- Perovskite (structure)1→11
- Polymer5→14
Where nanomaterials is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing nanomaterials patents in the United States
United States nanomaterials patent filing is cooling — 47,771 filings from 8,000 assignees (2016–2025), led by IBM, Intel, UNIV California; annual filings 4825→4147.
- IBM5897
- Intel3521
- UNIV California3277
- Massachusetts INST Technology2035
- 3M Innovative Properties2009
- Hewlett Packard Development1437
- UNIV Texas1099
- Molecular Imprints1056