Best Neurology Companies in California, United States
The 441 best Neurology companies in California, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Biosplice.
Our analysis of 50 Neurology companies
$7.4b in tracked funding; 74% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Neurology companies in California
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Neuralink 🦄 Provider of implantable brain-computer interfaces 78Funding top 15%Patents top 25%Moat top 25%Innovation top 27% All 10 signals ▾Fundingtop 15% Patentstop 25% Moattop 25% Innovationtop 27% Talenttop 28% Markettop 33% Growthtop 42% Techtop 44% Globalbottom 39% Newsbottom 24% Funding: Raised $680M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) Patents: 97 patents matched (strict assignee match) · 62 filings since 2022 vs 35 in 2017-21 rank vs industry peers · Fliar Intelligence Index 78/100 | $680M | 1 mo ago | 197 | Dongjin Seo Co-Founder | Apple iCloud MailGoogle WorkspaceGSAP+12 | 97 patents High‑density, biocompatible neural interface hardware and real‑time spike processing | 1 launch |
| 2 | Kriya Therapeutics Developer of therapeutic solutions for the treatment of diabetes 53Funding top 16%News top 24%Moat top 31%Growth top 43% All 8 signals ▾Fundingtop 16% Newstop 24% Moattop 31% Growthtop 43% Markettop 44% Talenttop 50% Globalbottom 37% Techbottom 32% Funding: Raised $618M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) News: 5 BI events in 12 mo (of 16 tracked, 3 types) · 3 high-value events (IPO/M&A/funding/contracts) in 12 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $618M | 10 mo ago | 159 | Shankar Ramaswamy Co-Founder & CEO | WordPress Site EditorWordPressMySQL+12 | — | — |
| 3 | Denali Therapeutics Developer of therapies to treat neurodegenerative diseases | $347M | 27 mo ago | 377 377 → 582 (+54%) · sector median +50% | Alexander Schuth Co-Founder | WordPressApple iCloud MailTypeScript+24 | 1,002 patents Neurodegenerative antibody therapies and enzyme‑fusion biologics for lysosomal disease treatment | — |
| 4 | Neurona Therapeutics Developer of cell-based therapies to treat intractable neurological diseases 55Funding top 22%Moat top 31%Growth top 32%AI top 45% All 8 signals ▾Fundingtop 22% Moattop 31% Growthtop 32% AItop 45% Talentbottom 49% Marketbottom 43% Globalbottom 39% Techbottom 30% Funding: Raised $316M across 9 rounds · 9 rounds over 18 yrs (0.5/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 55/100 | $316M | 14 mo ago | 67 67 → 116 (+73%) · sector median +50% | Cory Nicholas CEO | Apple iCloud MailApache HTTP ServerMicrosoft Advertising+5 | — | 1 award |
| 5 | MapLight Developer of therapeutic for central nervous system disorders 50Funding top 13%Growth top 28%Talent top 38%Moat top 39% All 7 signals ▾Fundingtop 13% Growthtop 28% Talenttop 38% Moattop 39% Globalbottom 39% Marketbottom 33% Techbottom 32% Funding: Raised $305M across 7 rounds · 7 rounds over 6 yrs (1.2/yr) Growth: Headcount 20 → 27 (+35%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 50/100 | $305M | 11 mo ago | 27 | Chris Kroeger Founder & CEO | WordPress Block EditorElementorWordPress+22 | — | — |
| 6 | Merge Labs Developer of brain-computer interfaces to maximize human ability, agency, experience 48Talent top 28%Funding top 31%AI top 45%Patents top 49% All 8 signals ▾Talenttop 28% Fundingtop 31% AItop 45% Patentstop 49% Innovationbottom 49% Techbottom 45% Globalbottom 42% Marketbottom 31% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $250M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $250M | 5 mo ago | — | Sumner Norman Co-Founder | Apple iCloud MailGoogle WorkspaceNode.js+9 | 40 patents Real-time multi-user AR collaboration and interactive media streaming platforms | — |
| 7 | Autobahn Therapeutics Provider of therapeutics for CNS disorders by the regenerative medicine | $228M | 23 mo ago | 23 | Kevin Finney Chairman and CEO | — | — | — |
| 8 | Aspen Neuroscience Provider of genomic-based personalised pluripotent stem cell therapy 64Funding top 17%Patents top 23%Moat top 28%Innovation top 33% All 10 signals ▾Fundingtop 17% Patentstop 23% Moattop 28% Innovationtop 33% Growthtop 35% Newstop 45% Marketbottom 49% Talentbottom 49% Techbottom 46% Globalbottom 45% Funding: Raised $224M across 5 rounds · 5 rounds over 7 yrs (0.7/yr) Patents: 57 patents matched (strict assignee match) · 51 filings since 2022 vs 6 in 2017-21 rank vs industry peers · Fliar Intelligence Index 64/100 | $224M | 6 mo ago | 94 | Damien Mcdevitt President | WordPress Block EditorWordPressMySQL+19 | 57 patents Patents concentrated in computing, sensing & instrumentation | — |
| 9 | Eledon Provider of therapeutics solution for organ or cellular transplantation in autoimmune and neurodegenerative… | $201M | 25 mo ago | 17 17 → 42 (+147%) · sector median +50% | — | DrupalApple iCloud MailMicrosoft 365+24 | — | — |
| 10 | Tenvie Developer of small molecule therapies for neurological, cardiometabolic, and ophthalmic diseases | $200M | 17 mo ago | — | Brian Cuneo Co-Founder & CLO | — | — | 4 job openings |
| 11 | Ventyx Biosciences Developer of therapeutics to treat autoimmune diseases | $165M | 20 mo ago | 79 | Raju Mohan Founder & CEO | DrupalPHPAmazon Web Services+18 | 54 patents TYK2 kinase inhibitor design, synthesis, and crystalline forms for immunomodulatory therapeutics | — |
| 12 | Cala Health Developer of a wearable non-invasive neuromodulation device 60Funding top 17%Product top 21%Innovation top 22%Patents top 26% All 11 signals ▾Fundingtop 17% Producttop 21% Innovationtop 22% Patentstop 26% Moattop 26% Talenttop 38% Techtop 46% Growthbottom 44% Marketbottom 43% Globalbottom 42% Newsbottom 21% Funding: Raised $157M across 7 rounds · 7 rounds over 13 yrs (0.5/yr) Product: 6 distinct product lines · Company stage: Series D rank vs industry peers · Fliar Intelligence Index 60/100 | $157M | 1 mo ago | 50 50 → 122 (+144%) · sector median +50% | Kate Rosenbluth Founder and Co-President | WordPressApple iCloud MailGoogle Workspace+31 | 243 patents Wearable peripheral nerve stimulation devices for tremor, movement and musculoskeletal disorder therapy | 1 award |
| 13 | Alto Neuroscience AI-driven drug discovery platform for neurological diseases based on patients biomarkers 72Funding top 12%Patents top 25%Growth top 30%Moat top 32% All 11 signals ▾Fundingtop 12% Patentstop 25% Growthtop 30% Moattop 32% Innovationtop 33% Techtop 45% AItop 45% Globalbottom 49% Talentbottom 49% Newsbottom 44% Marketbottom 40% Funding: Raised $145M across 9 rounds · 9 rounds over 7 yrs (1.3/yr) Patents: 57 patents matched (strict assignee match) · 57 filings since 2022 vs 0 in 2017-21 rank vs industry peers · Fliar Intelligence Index 72/100 | $145M | 3 mo ago | 34 | Amit Etkin Founder & CEO | BugHerdApple iCloud MailGoogle Workspace+15 | 57 patents Neuropsychiatric therapeutics: combinatorial dopaminergic/serotonergic drugs and EEG‑guided patient selection | 1 award |
| 14 | Nura Bio Provider of solution for diagnosis of a neurological disorder and neuroprotective medicines | $141M | 21 mo ago | 25 | Marc Freeman Co-Founder | — | — | — |
| 15 | Route 92 Medical Developer of next-generation products for neurointerventional procedures 69Funding top 14%Innovation top 18%Patents top 21%Moat top 29% All 10 signals ▾Fundingtop 14% Innovationtop 18% Patentstop 21% Moattop 29% Growthtop 32% Techtop 50% Talentbottom 49% Marketbottom 45% Newsbottom 41% Globalbottom 40% Funding: Raised $138M across 9 rounds · 9 rounds over 5 yrs (1.8/yr) Innovation: 223 patents (top 12% of patent-holders) · 137 filings since 2022 vs 82 in 2017-21 rank vs industry peers · Fliar Intelligence Index 69/100 | $138M | 5 mo ago | 51 | Tony Chou Founder & CEO | WordPress Block EditorWordPressMySQL+23 | 223 patents Neurovascular aspiration catheters for minimally invasive stroke thrombectomy | — |
| 16 | Latigo Biotherapeutics Developer of non-opioid pain medicines for central nervous system | $135M | 16 mo ago | 17 | Nima Farzan Chief Executive Officer | — | 34 patents Voltage-gated sodium channel inhibitor drugs for pain and neurological therapies | — |
| 17 | Ambagon Developer of small-molecule therapeutics for the treatment of cancer | $103M | 16 mo ago | 49 | Luc Brunsveld Co-Founder | WordPressMySQLPHP+20 | — | — |
| 18 | Allay Therapeutics Developer of drugs for post-surgical pain management 42Funding top 18%Moat top 39%Market bottom 44%Global bottom 38% All 5 signals ▾Fundingtop 18% Moattop 39% Marketbottom 44% Globalbottom 38% Newsbottom 21% Funding: Raised $102M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) Moat: Editorial + unicorn rating 7/10 · 10 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 42/100 | $102M | 12 mo ago | 50 | — | — | — | — |
| 19 | Nudge Developer of whole-brain interfaces intended to improve human-brain interaction | $100M | 10 mo ago | — | Quintin Frerichs Co-Founder | Apple iCloud MailGoogle WorkspaceRadix UI+8 | 12 patents Automated, low-interaction glucose monitoring and insulin delivery systems for diabetes care | — |
| 20 | Openwater Provider of imaging technologies for medical diagnosis and treatments | $100M | 21 mo ago | — | Mary Lou Jepsen Founder & CEO | Wix eCommerceCart FunctionalityWix+17 | — | — |
| 21 | Octave Bioscience Provider of AI-based molecular diagnostic tools for neurodegenrative diseases 69Funding top 20%Innovation top 32%Growth top 35%Product top 35% All 11 signals ▾Fundingtop 20% Innovationtop 32% Growthtop 35% Producttop 35% Talenttop 38% Moattop 39% AItop 45% Techtop 48% Marketbottom 43% Newsbottom 42% Globalbottom 38% Funding: Raised $88.0M across 8 rounds · 8 rounds over 9 yrs (0.9/yr) Innovation: 2 product lines · Deep-tech classification: Tech Hardware rank vs industry peers · Fliar Intelligence Index 69/100 | $88M | 9 mo ago | 90 | William Hagstrom Co-Founder & CEO | WordPressApple iCloud MailGoogle Workspace+26 | — | 1 launch |
| 22 | Emboline Developer of an aortic embolic protection device 48Funding top 22%Moat top 26%Innovation top 28%Patents top 29% All 9 signals ▾Fundingtop 22% Moattop 26% Innovationtop 28% Patentstop 29% Talenttop 38% Techbottom 44% Newsbottom 42% Globalbottom 40% Marketbottom 28% Funding: Raised $81.9M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 112 patents rank vs industry peers · Fliar Intelligence Index 48/100 | $82M | 3 mo ago | 13 13 → 23 (+77%) · sector median +50% | Amir Belson Founder & CTO | WordPressMySQLPHP+16 | 112 patents Embolic protection and delivery devices for cardiovascular catheter procedures | — |
| 23 | Therini Bio Limited information available | $62M | 13 mo ago | 13 13 → 15 (+15%) · sector median +50% | Daniel Burgess CEO | — | — | — |
| 24 | CuraSen Provider of therapeutics for neurodegenerative disorder | $60M | 21 mo ago | 16 | Mehrdad Shamloo Co-Founder | — | — | — |
| 25 | Noctrix Health Developer of wearable therapeutic device to treat neurological disorders | $57M | 9 mo ago | 8 | — | WordPressApple iCloud MailMySQL+16 | — | — |
| 26 | ReviR Therapeutics Developer of RNA-based therapeutics for multiple diseases 35Funding top 26%AI top 45%Moat top 47%Talent bottom 49% All 8 signals ▾Fundingtop 26% AItop 45% Moattop 47% Talentbottom 49% Marketbottom 36% Globalbottom 36% Techbottom 31% Newsbottom 18% Funding: Raised $54.0M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) AI: Product described with: machine learning rank vs industry peers · Fliar Intelligence Index 35/100 | $54M | 1 mo ago | 29 | Yang Li Co-Founder | UbuntuElement UIVue.js+6 | — | 1 partnership |
| 27 | Titan Pharma A specialty pharmaceutical company developing proprietary therapeutics for select chronic diseases | $38M | 11 mo ago | 11 | — | Apple iCloud MailMicrosoft 365Apache HTTP Server+8 | — | — |
| 28 | EicOsis Developing safer pain and inflammation treatments by restoring the body's natural healing | $31M | 14 mo ago | 14 14 → 7 (-50%) · sector median +50% | Robert Gregoire Co-Founder & CEO | — | 24 patents Solid-form pharmaceutical innovations for epoxide hydrolase and kinase inhibitor therapies | — |
| 29 | Neuro42 AI Provider of MRI and robotics technology for neurology | $30M | 9 mo ago | 34 | Abhita Vohra Co-Founder & CSO | WebflowSwiperjQuery+8 | 42 patents Low-field MRI hardware integration, AI‑enhanced image reconstruction, and electromagnetic interference mitigation. | — |
| 30 | Subsense Developer of non-surgical brain-computer interfaces using biocompatible nanoparticles | $27M | 6 mo ago | — | Tetiana Aleksandrova Founder & CEO | WordPress Block EditorWebflowWordPress+16 | — | — |
| 31 | OncoSynergy Developer of resistance mechanism inhibitors to treat cancer 11Funding top 28%Moat top 32%Patents bottom 48%Global bottom 42% All 6 signals ▾Fundingtop 28% Moattop 32% Patentsbottom 48% Globalbottom 42% Innovationbottom 33% Marketbottom 18% Funding: Raised $26.7M across 7 rounds · 7 rounds over 8 yrs (0.9/yr) Moat: Editorial + unicorn rating 5/10 · IP moat: 26 patents rank vs industry peers · Fliar Intelligence Index 11/100 | $27M | 1 mo ago | 3 | — | — | 26 patents Patents concentrated in chemistry & materials | — |
| 32 | Epalex Developer of therapies for treating neurological disorders | $26M | 7 mo ago | 2 | Brendan Magrab CEO | — | 30 patents Prodrug and formulation technologies for intravenous anesthetic propofol delivery | — |
| 33 | Magnus Medical Provider of non invasive neuromodulation system for depression treatment | $25M | 16 mo ago | 11 | Brandon Bentzley Co-Founder | Apple iCloud MailGoogle WorkspaceVue.js+8 | — | — |
| 34 | SiteOne Therapeutics Sodium ion channel 1.7 (Na 1.7) inhibitors for acute and chronic pain. | $24M | 13 mo ago | — | John Mulcahy Co-Founder & CEO | — | — | — |
| 35 | NeOnc Technologies Holdings Developer of a novel drug delivery platform for CNS diseases 53Funding top 30%Growth top 35%Innovation top 37%Talent top 38% All 8 signals ▾Fundingtop 30% Growthtop 35% Innovationtop 37% Talenttop 38% Techtop 42% Patentstop 42% Globalbottom 42% Marketbottom 25% Funding: Raised $22.3M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $22M | 4 mo ago | — | Thomas Chen Founder & Co-CEO | WordPress Block EditorElementorCart Functionality+26 | 48 patents Monoterpene-derived anticancer drugs, especially perillyl alcohol formulations for cancer therapy. | — |
| 36 | Aneuvo Developer of a medical device for the treatment of spinal cord injuries 32Growth top 35%Funding top 39%Tech top 49%Talent bottom 49% All 6 signals ▾Growthtop 35% Fundingtop 39% Techtop 49% Talentbottom 49% Marketbottom 25% Globalbottom 25% Growth: Fresh capital in last 24 mo Funding: Raised $22.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 32/100 | $22M | 3 mo ago | — | Yi Lo CEO | WordPressMySQLPHP+22 | — | — |
| 37 | SOLEY Therapeutics Developer of stem cell secreted factors for the treatment of myocardial infarction and stroke | $20M | 5 mo ago | 10 | Yerem Yeghiazarians Co-Founder & CEO | — | — | 1 job opening · 1 launch |
| 38 | Lighthouse Pharma Developer of therapeutics for neurology and infectious diseases 11Funding top 46%Talent bottom 49%Tech bottom 45%Global bottom 25% All 5 signals ▾Fundingtop 46% Talentbottom 49% Techbottom 45% Globalbottom 25% Marketbottom 18% Funding: Raised $15.2M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 11/100 | $15M | 1 mo ago | 4 | Casey Lynch Chief Executive Officer | WixSentryBootstrap+10 | — | 1 job opening |
| 39 | Novoron Bioscience Developer of therapeutics for neurological diseases 22Funding top 34%Innovation top 38%Product top 48%Global bottom 32% All 6 signals ▾Fundingtop 34% Innovationtop 38% Producttop 48% Globalbottom 32% Marketbottom 25% Techbottom 24% Funding: Raised $15.1M across 10 rounds · 10 rounds over 11 yrs (0.9/yr) Innovation: 3 product lines rank vs industry peers · Fliar Intelligence Index 22/100 | $15M | 3 mo ago | 11 11 → 16 (+45%) · sector median +50% | — | — | — | 1 job opening · 1 partnership |
| 40 | Navega Therapeutics Developer of gene therapy products for chronic pain management | $15M | 13 mo ago | 10 | Prashant Mali Co-Founder | — | — | — |
| 41 | SonALAsense Developer of therapeutic solutions for treating cancer, neurological disorders & others | $14M | 14 mo ago | 10 | Stuart Marcus Md Founder and Chief Scientific Officer | WixSentryBootstrap+12 | 22 patents Ultrasound‑enhanced drug delivery targeting tumor metabolism in low‑grade cancers | — |
| 42 | Neuronoff Developer of a neuromodulation device to restore and improve organ activity | $12M | 8 mo ago | 16 16 → 21 (+31%) · sector median +50% | Andrew Shoffstall Co-Founder | — | 48 patents Injectable flexible electrodes for minimally invasive neuromodulation and tissue ablation | — |
| 43 | Bloom Science Developer of therapies to treat neurological diseases | $12M | 14 mo ago | 26 | Christopher Reyes CEO | — | — | — |
| 44 | Cordance Medical Developer of a non-invasive medical device to open the blood-brain barrier | $9M | 6 mo ago | 9 | Bhaskar Ramamurthy Founder/CTO | — | — | — |
| 45 | Spinogenix Developer of therapeutics for brain injury and neurodegenerative diseases | $9M | 6 mo ago | 7 | Stella Sarraf Founder & CEO | WordPressMySQLPHP+20 | 58 patents Small-molecule spinogenesis promoters for ophthalmic, metabolic, and neurodegenerative therapies | 1 launch |
| 46 | SpineX Developer of a medical device for neurological conditions | $6M | 9 mo ago | 15 | — | WordPressMySQLPHP+23 | 5 patents Non‑invasive wearable CNS neuromodulation devices for spinal pain and motor disorder therapy | — |
| 47 | Elysium Therapeutics Developing innovative solutions to combat opioid overdose and reduce opioid abuse | $2M | 4 mo ago | 2 | Alex Sturmer President | — | — | — |
| 48 | Acumen Pharmaceuticals Developer of monoclonal antibody therapeutics for Alzheimer's disease | $2M | 3 mo ago | 52 52 → 67 (+29%) · sector median +50% | — | DrupalApple iCloud MailMicrosoft 365+22 | — | 1 partnership |
| 49 | Hillhurst Biopharmaceuticals Developer of carbon monoxide based therapeutics | $2M | 6 mo ago | — | Andrew Gomperts CEO & President | — | — | — |
| 50 | AcuraStem Developer of therapeutics for neurodegenerative diseases | $780K | 1 mo ago | 14 | Justin Ichida Co-Founder | — | 70 patents Antisense oligonucleotide therapeutics targeting SYF2, PIKfyve, UNC13A gene expression. | 1 expansion |
Top 12 Neurology companies in California
#1
Series E · Fremont, California · founded 2016 · 197 employees$680Mraised▾
Provider of implantable brain-computer interfaces. It offers flagship product the N1 Implant the Link which is a coin-sized device designed to decode neural signals and enable users to control digital devices using only their thoughts. It also has an experimental device called Blindsight to restore vision in individuals with optic nerve damage by directly stimulating the visual cortex.
- May 2026Series E—
- May 2025Series E$650M
- Nov 2023Series D$43M
- Aug 2023Series D$323.2M
#2
Series D · Stanford, California · founded 2013 · 50 employees$157.1Mraised▾
Developer of a wearable non-invasive neuromodulation device. The company has developed a neuromodulation device that aims to provide relief of hand tremors in adults with essential tremors. It combines a watch-like device with an implantable sensor that externally stimulates peripheral nerves to reduce the same. The company has also developed a portable medical device with sensors to monitor the physical movement of a patient wearing or carrying the device.
- Apr 2026Conventional Debt$50M
- Oct 2025Series D$50M
- Dec 2024Series D$50M
- May 2022Series D—
#3
Public · San Francisco, California · founded 2019 · 34 employees$144.7Mraised▾
AI-driven drug discovery platform for neurological diseases based on patients biomarkers. The company's platform measures patients biomarkers like EEG and wearable data, behavioral patterns, genetics, and other factors to develop personalized psychiatric drugs. The company has pipeline of drugs including ALTO-100 for depression, ALTO-101 for neurodegenerative diseases, and more.
- Mar 2026Post IPO$120M
- Oct 2025Post IPO$50M
- Nov 2023Series C$45M
- Jan 2023Venture Debt—
#4
Seed · San Francisco, California · founded 2025$250Mraised▾
Developer of brain-computer interfaces to maximize human ability, agency, experience. It focuses on creating new approaches to interact with the brain. The aim is to develop high-bandwidth brain-computer interfaces. These interfaces integrate with advanced artificial intelligence. The goal is to make the technology safe and accessible. The company seeks to restore lost abilities and support healthier brain states. It also aims to deepen connections and expand creative potential.
- Jan 2026Seed$250M
#5
Series F · San Mateo, California · founded 2015 · 51 employees$137.7Mraised▾
Developer of next-generation products for neurointerventional procedures. The company's products include the FreeClimb Catheter Systems, which are advanced neurointervention systems to provide superior performance, and the Monopoint Reperfusion System to streamline delivery and enable super-bore aspiration at the most common stroke targets.
- Jan 2026Series F$50M
- Jun 2024Series F$50.4M
- Nov 2023Series F$31.3M
- Dec 2021Conventional Debt$55M
#6
Series D · Santa Cruz, California · founded 2011 · 13 employees$81.9Mraised▾
Developer of an aortic embolic protection device. The Emboliner protects the brain and the rest of the body from embolic events (e.g., strokes) during cardiovascular procedures, especially catheter-based heart valve replacements. It is a Pro-Sheath device having a “sock-like” mesh filter that is deployed in the patient’s aorta at the beginning of the interventional procedure. The valve replacement surgery is conducted with the Pro-Sheath in place, providing embolic protection during the procedure.
- Mar 2026Series D$20M
- May 2021Series D$55.4M
- Jan 2021Series C$11.6M
- Jan 2020Series B$5M
#7
Series A · San Francisco, California · founded 2021 · 29 employees$54Mraised▾
Developer of RNA-based therapeutics for multiple diseases. The company is leveraging machine learning technology and innovative RNA techniques to develop medicines for the treatment of cancer, rare genetic disorders, and infectious diseases.
- Apr 2026Series A—
- Nov 2025Grant (prize money)$4.6M
- Jul 2024Series A$30M
- Jan 2022Seed$20M
#8
Series C · San Diego, California · founded 2018 · 94 employees$224Mraised▾
Provider of genomic-based personalized pluripotent stem cell therapy. It offers regenerative cell treatment like dopaminergic neurons for Parkinson's disease and other neurological disorders. It maintains the genetic-based quality control to avoid the mutation of cells used for therapy.
- Nov 2025Series C$115M
- Dec 2022Conventional Debt$40M
- May 2022Series B$147.5M
- Apr 2020Series A$70M
#9
Series D · Redwood City, California · founded 2012 · 159 employees$617.6Mraised▾
Developer of therapeutic solutions for the treatment of diabetes. The company has developed AAV-based gene therapies for the treatment of type 1 and type 2 diabetes. Its drug candidate KT-A112 contains insulin and glucokinase proteins that help in treating Type 1 & Type 2 diabetes mellitus. It also provides KT-A522 with glucagon-like peptide (GLP-1) receptor agonist for the treatment of Type 2 diabetes, KT-A832 insulin growth factor that helps in treating diabetes mellitus.
- Jul 2025Series D$320.8M
- May 2022Series C$430M
- Jun 2021Series B$100M
- May 2020Series A$87.6M
#10
Acquired · San Francisco, California · founded 2011 · 3 employees$26.7Mraised▾
Developer of resistance mechanism inhibitors to treat cancer. It targets multiple hallmarks of cancer progression and have demonstrated efficacy as monotherapy and in strategic combinations. The lead drug program OS2966 therapeutic antibody blocking a cell surface receptor for the treatment of glioblastoma, ovarian, pancreatic cancer, and malignant meningioma.
- May 2022Series A$3.5M
- Nov 2020Conventional Debt$250K
- Sep 2020Series A$3.2M
- Jan 2020Grant (prize money)$300K
#11
Public · Redwood City, California · founded 2018 · 27 employees$305Mraised▾
Developer of therapeutic for central nervous system disorders. The company's flagship product ML-004 helps in treating mental disorders, Alzheimer's agitation, and others. It has also developed ML-007, ML-009 for treating dyskinesia, schizophrenia, and ML-016 for treating anhedonia.
- Jul 2025Series D$372.5M
- Oct 2023Series C$225M
- Jul 2023Series C$50M
- Mar 2021Series B$30M
#12
Seed · San Diego, California · founded 2013 · 11 employees$15.1Mraised▾
Developer of therapeutics for neurological diseases. It offer therapies for nerve regeneration in the central nervous system (CNS) specifically, spinal cord injury (SCI).It offer biologic therapeutics to inhibit the LRP1/Rho pathway and, thus, promote neuronal and axonal regeneration.
- Mar 2026Seed—
- Feb 2025Grant (prize money)$844.7K
- Dec 2022Seed$12.1M
- Jan 2022Grant (prize money)—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Neurology coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding falling · growth flat
How research on Neurotech in California is moving
A read on the academic research around Neurotech in California — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 761 papers.
UC San Francisco, UCLA, and USC lead California's neurotech research, predominantly advancing neurological disorder treatments and brain-computer interfaces with a cautiously optimistic tone.
- University of California, San Francisco267
- University of California, Los Angeles126
- University of Southern California79
- University of California, Berkeley66
- California Institute of Technology60
- Deep brain stimulation16→33
- Neuromodulation2→17
- Neurostimulation3→16
- Stimulation6→17
- Sensory system2→6
- Deep brain stimulation66→93
- Stimulation21→47
- Neurostimulation17→31
- Thalamus3→16
- Neuromodulation7→19
- Stimulation1→15
- Neurostimulation2→12
- Deep brain stimulation35→42
- Neuroscience14→21
- Neuromodulation2→8