2665 indexable Oncology companies headquartered in United States, ranked by total equity funding and recent funding momentum. Combined disclosed equity funding of $112.1B across 1702 funded companies, including 8 unicorns.
| # | Company | Funding | Valuation | Stage | Latest round | Employees | Founded | Momentum |
|---|---|---|---|---|---|---|---|---|
| 1 |
GRAIL
Developer of a screening platform for circulating tumor DNA to detect cancer |
$2B | — | Public | Post IPO Oct 2025 | 491 | 2016 | ↑ Active |
| 2 |
Senti Bio
Developer of cell and gene therapies for patients living with incurable diseases |
$158M | — | Public | Post IPO May 2026 | 122 | 2016 | ↑ Active |
| 3 |
Terremoto
Developer of small-molecule therapeutics for cancer treatment |
$250M | — | Series C | Series C Apr 2026 | 35 | 2021 | ↑ Active |
| 4 |
Iambic Therapeutics
Provider of AI-driven drug discovery platform for the treatment of cancer |
$206.2M | — | Series C | Series C Apr 2026 | 50 | 2019 | ↑ Active |
| 5 |
CytoDyn
Developer of humanized monoclonal antibodies for the treatment and prevention of HIV infection |
$249.7M | — | Public | Post IPO Mar 2026 | 12 | 2002 | ↑ Active |
| 6 |
Century Therapeutics
Developer of therapeutics for the treatment of autoimmune diseases and cancer |
$410M | — | Public | Post IPO Jan 2026 | 94 | 2018 | ↑ Active |
| 7 |
CREATE Medicines
Developer of messenger ribonucleic acid therapies for immune cell programming |
$122M | — | Series B | Series B May 2026 | — | 2019 | ↑ Active |
| 8 |
Guardant Health
Developer of digital sequencing technology for cancer detection |
$557.5M | — | Public | Post IPO Nov 2025 | 1,351 | 2012 | ↑ Active |
| 9 |
Adela
Developer of a platform for detection of cancer |
$108.5M | — | Series A | Series A Apr 2026 | 62 | 2021 | ↑ Active |
| 10 |
Summit
Developer of therapeutics for oncology and rare diseases |
$713M | — | Public | Post IPO Oct 2025 | 99 | 2003 | ↑ Active |
| 11 |
Precision BioSciences
Developer of gene editing therapies to treat rare genetic diseases |
$135.7M | — | Public | Post IPO Mar 2026 | 236 | 2006 | ↑ Active |
| 12 |
ClearNote Health
Developer of non-invasive cancer detection methods |
$70M | — | Series D | Series D May 2026 | 45 | 2016 | ↑ Active |
| 13 |
Celularity
Developer of allogeneic cell therapies to treat multiple diseases |
$290M | — | Public | Post IPO Dec 2025 | 225 | 2016 | ↑ Active |
| 14 |
Karyopharm
Biopharmaceutical company focused on developing and commercializing innovative cancer therapies |
$98.4M | — | Public | Post IPO Mar 2026 | 325 | 2008 | ↑ Active |
| 15 |
Delfi Diagnostics
Provider of DNA sequencing for cancer detection |
$331.6M | — | Series B | Conventional Debt Dec 2025 | 197 | 2019 | ↑ Active |
| 16 |
Orca Bio
Unicorn Developer of Allogeneic cell therapy for cancer, autoimmune diseases and genetic blood disorders |
$300M | $1B as of 2020 |
Series F | Series F Jan 2026 | 66 | 2016 | ↑ Active |
| 17 |
Parabilis Medicines
Developer of peptide therapeutics for the treatment of severe diseases |
$305M | — | Series F | Series F Jan 2026 | — | 2016 | ↑ Active |
| 18 |
Treeline Biosciences
Developer of transformative precision medicines to treat cancer |
$895.4M | — | Series A | Series A Aug 2025 | 148 | 2021 | ↑ Active |
| 19 |
TEMPEST THERAPEUTICS
Developing targeted, immune-mediated oral cancer therapies for broad patient benefit |
$88.2M | — | Public | Post IPO Mar 2026 | 19 | 2011 | ↑ Active |
| 20 |
Bonum Therapeutics
Manufacturer of cytokine based drugs |
$93M | — | Series B | Series B Apr 2026 | 54 | 2021 | ↑ Active |
| 21 |
LTZ Therapeutics
Developer of immunotherapies to treat cancer and other diseases |
$47M | — | Series B | Series B May 2026 | 23 | 2021 | ↑ Active |
| 22 |
Atavistik
Developer of allosteric therapeutics for precision oncology and rare diseases |
$100M | — | Series B | Series B Mar 2026 | 33 | 2021 | ↑ Active |
| 23 |
Rakuten Medical
Developer of a photoimmunotherapy platform for treating cancer |
$874.3M | — | Series F | Series F Jul 2025 | 110 | 2013 | ↑ Active |
| 24 |
Third Arc Bio
Developer of therapetics for cancer and immunological diseases |
$165M | — | Series A | Series A Feb 2026 | — | 2022 | ↑ Active |
| 25 |
Verismo Therapeutics
Developer of CAR-T cell therapies for cancer |
$50M | — | Series A | Series A Apr 2026 | 9 | 2020 | ↑ Active |
| 26 |
HistoSonics
Ultrasound-based tissue ablation |
$315.7M | — | Acquired | Series E Oct 2025 | 56 | 2009 | ↑ Active |
| 27 |
Crossbow
Developer of antibody therapies for cancer treatment |
$80M | — | Series B | Series B Mar 2026 | 24 | 2021 | ↑ Active |
| 28 |
Moderna
Developer of mRNA-based therapeutics for a wide range of diseases |
$2.8B | — | Public | Grant (prize money) Jan 2025 | 1,312 | 2010 | ↑ Active |
| 29 |
BlossomHill Therapeutics
Provider of the drug for the treatment of oncology and autoimmune disorders |
$259.6M | — | Series B | Series B Nov 2025 | 14 | 2020 | ↑ Active |
| 30 |
OncoSynergy
Developer of resistance mechanism inhibitors to treat cancer |
$26.7M | — | Acquired | Series A May 2026 | 3 | 2011 | ↑ Active |
| 31 |
Artelo Biosciences
Modifying lipid-signaling pathways to improve cancer treatments |
$39.9M | — | Public | Post IPO Mar 2026 | 7 | 2011 | ↑ Active |
| 32 |
TORL BioTherapeutics
Developer of antibody-based therapeutics for the treatment of cancer |
$350M | — | Series C | Series C Oct 2025 | — | 2019 | ↑ Active |
| 33 |
Kanvas Biosciences
Provider of imaging solutions for microbial research and infectious diseases |
$29.5M | — | Series A | Series A May 2026 | 10 | 2021 | ↑ Active |
| 34 |
TRexBio
Developer of therapeutics for immunology and cancer |
$85M | — | Series B | Series B Jan 2026 | 65 | 2019 | ↑ Active |
| 35 |
Vyriad
Developer of oncolytic-virus-based immunotherapies for cancer treatment |
$100M | — | Series B | Series B Dec 2025 | 37 | 2016 | ↑ Active |
| 36 |
Cue Biopharma
Precision immunotherapies to transform patients' lives by selectively modulating the immune system |
$26.4M | — | Public | Post IPO May 2026 | 51 | 2015 | ↑ Active |
| 37 |
Caris Life Sciences
Unicorn Developer of panomic disease profiling technologies for cancer precision medicine |
$1.1B | $7.8B as of 2021 |
Public | Series D Apr 2025 | 1,339 | 1996 | ↑ Active |
| 38 |
NextCure
Developer of next-generation immuno-oncology-based drugs |
$175.4M | — | Public | Post IPO Nov 2025 | 87 | 2015 | ↑ Active |
| 39 |
Sirnaomics
Developer of RNA based therapeutics for the treatment of cancer and fibrosis disease |
$267M | — | Public | Post IPO Sep 2025 | 88 | 2007 | ↑ Active |
| 40 |
Aprea
Developer of small molecule therapeutics targeting tumor suppressor proteins |
$113.2M | — | Public | Post IPO Dec 2025 | 13 | 2003 | ↑ Active |
| 41 |
Solve Therapeutics
Developer of antibody-based therapies targeting tumor-specific antigens for cancer treatment |
$195M | — | Series D | Series D Nov 2025 | — | 2021 | ↑ Active |
| 42 |
Tango Therapeutics
Developer of drugs for the treatment of cancer |
$165M | — | Public | Post IPO Oct 2025 | 140 | 2017 | ↑ Active |
| 43 |
Athos Therapeutics
Developer of AI-based therapeutics for treating autoimmune diseases |
$28M | — | Series A | Series A Apr 2026 | 18 | 2019 | ↑ Active |
| 44 |
Incyclix Bio
A next-generation cell cycle control company advancing precision treatments for cancer |
$30M | — | Series B | Series B Apr 2026 | 6 | 2020 | ↑ Active |
| 45 |
Lyell Immunopharma
Developer of CAR- T therapy for cancer treatment |
$493M | — | Public | Post IPO Jul 2025 | 224 | 2018 | ↑ Active |
| 46 |
Enveric
Developer of small-molecule therapeutics for the treatment of neuropsychiatric disorders |
$26.4M | — | Public | Post IPO Apr 2026 | 25 | 1994 | ↑ Active |
| 47 |
Primmune Therapeutics
Developer of immunotherapies for treating cancer |
$46.8M | — | Series B | Series B Jan 2026 | 9 | 2017 | ↑ Active |
| 48 |
Odyssey
Developer of immunotherapeutics for immunological and cancer diseases |
$503.2M | — | Public | Series D Jun 2025 | 108 | 2018 | ↑ Active |
| 49 |
CASI Pharmaceuticals
Developer of therapeutics for the treatment of cancer |
$69.5M | — | Public | Post IPO Dec 2025 | 234 | 1991 | ↑ Active |
| 50 |
Agenusbio
Developer of immunotherapies to treat cancer |
$440.7M | — | Public | Post IPO Jun 2025 | 533 | 1994 | ↑ Active |
Developer of a screening platform for circulating tumor DNA to detect cancer. The company is developing a test called "Galleri" a pan-cancer screening test by measuring circulating nucleic acids in the blood. Its proprietary platform uses the ultra-deep sequencing technique to measure levels of circulating tumor DNA in the patient's blood.
Developer of cell and gene therapies for patients living with incurable diseases. The company has developed its proprietary synthetic biology platform to produce cell and gene therapies for cancer treatment. The company's pipeline is comprised of cell therapies engineered with Gene Circuits to target difficult to treat liquid and solid tumors. It offers CAR-NK-based therapies for multiple cancer and tumors.
Developer of small-molecule therapeutics for cancer treatment. It provides a lysine-targeted covalency platform to develop therapies against known drug targets for oncology.
Provider of AI-driven drug discovery platform for the treatment of cancer. It offers an AI driven discovery platform and has discovered two candidates known as IAM-H1, a highly selective and brain penetrant inhibitor of HER2 and its oncogenic mutants, and IAM-C1 a potential first-in-class selective dual CDK2/4 inhibitor to address unmet needs in terms of therapeutic window and treatment resistance in cell cycle drive
Developer of humanized monoclonal antibodies for the treatment and prevention of HIV infection. It offers lead candidate, PRO 140,for HIV with demonstrated antiviral activity in men. PRO 140 blocks the HIV co-receptor CCR5 on T-cells that prevent viral entry.
Developer of therapeutics for the treatment of autoimmune diseases and cancer. The company's iPSC-derived cell therapy platform that integrates cutting-edge gene editing, protein engineering, technical development and manufacturing capabilities to generate allogeneic, iPSC-derived therapies for autoimmune diseases and cancer.
Developer of messenger ribonucleic acid therapies for immune cell programming. These therapies utilize lipid nanoparticle delivery systems to modify immune cells directly within the body. The technology targets specific cell types to address conditions related to oncology and autoimmunity. The approach focuses on the expression of chimeric antigen receptors to facilitate immune responses against disease targets.
Developer of digital sequencing technology for cancer detection. The product Guardant360 offers real-time, biopsy-free tumor sequencing for the analysis and identification of tumor-associated treatment options. Also, it has developed analytical tools, including a tumor response map and a mobile-enabled physician portal.
Developer of a platform for detection of cancer. The company has developed a blood test for genome-wide methylation analysis technology to detect kidney cancer and intracranial brain tumors. It allows distinguishing the informative methylated regions of the genome from non-informative regions and targets for sequencing.
Developer of therapeutics for oncology and rare diseases. It offers Ivonescimab which combines the effects of immunotherapy via a blockade of PD-1 with the anti-VEGF effect for the treatment of non-small cell lung cancer.
Developer of gene editing therapies to treat rare genetic diseases. The company utilizes novel proprietary ARCUS platform to develop in vivo gene editing therapies for sophisticated gene edits, including gene insertion, excision, and elimination. The company's pipeline include therapies for Hepatitis B, duchenne muscular dystrophy, and more.
Developer of non-invasive cancer detection methods. It offers a 5-hydroxymethylcytosine-based epigenomic platform and cell-free DNA-based assays to measure biological changes in cells and detect cancers with high mortality rates when they respond best to treatment.
Rankings are computed by Radar (Fliar BI) from the Radar company master and are updated periodically. Funding and momentum scores use disclosed equity-funding data only. Figures may lag private rounds. Last updated 2026-06-16.