Oncology · United States, India

Best Oncology Companies in United States

Updated 2026-06-16 · Ranked by funding & momentum

2665 indexable Oncology companies headquartered in United States, ranked by total equity funding and recent funding momentum. Combined disclosed equity funding of $112.1B across 1702 funded companies, including 8 unicorns.

2,665
Companies
$112.1B
Total Funding
1,702
Funded
8
Unicorns
28
Rounds (90d)

Ranked: Best Oncology companies in United States

#CompanyFundingValuationStage Latest roundEmployeesFoundedMomentum
1 GRAIL
Developer of a screening platform for circulating tumor DNA to detect cancer
$2B Public Post IPO Oct 2025 491 2016 ↑ Active
2 Senti Bio
Developer of cell and gene therapies for patients living with incurable diseases
$158M Public Post IPO May 2026 122 2016 ↑ Active
3 Terremoto
Developer of small-molecule therapeutics for cancer treatment
$250M Series C Series C Apr 2026 35 2021 ↑ Active
4 Iambic Therapeutics
Provider of AI-driven drug discovery platform for the treatment of cancer
$206.2M Series C Series C Apr 2026 50 2019 ↑ Active
5 CytoDyn
Developer of humanized monoclonal antibodies for the treatment and prevention of HIV infection
$249.7M Public Post IPO Mar 2026 12 2002 ↑ Active
6 Century Therapeutics
Developer of therapeutics for the treatment of autoimmune diseases and cancer
$410M Public Post IPO Jan 2026 94 2018 ↑ Active
7 CREATE Medicines
Developer of messenger ribonucleic acid therapies for immune cell programming
$122M Series B Series B May 2026 2019 ↑ Active
8 Guardant Health
Developer of digital sequencing technology for cancer detection
$557.5M Public Post IPO Nov 2025 1,351 2012 ↑ Active
9 Adela
Developer of a platform for detection of cancer
$108.5M Series A Series A Apr 2026 62 2021 ↑ Active
10 Summit
Developer of therapeutics for oncology and rare diseases
$713M Public Post IPO Oct 2025 99 2003 ↑ Active
11 Precision BioSciences
Developer of gene editing therapies to treat rare genetic diseases
$135.7M Public Post IPO Mar 2026 236 2006 ↑ Active
12 ClearNote Health
Developer of non-invasive cancer detection methods
$70M Series D Series D May 2026 45 2016 ↑ Active
13 Celularity
Developer of allogeneic cell therapies to treat multiple diseases
$290M Public Post IPO Dec 2025 225 2016 ↑ Active
14 Karyopharm
Biopharmaceutical company focused on developing and commercializing innovative cancer therapies
$98.4M Public Post IPO Mar 2026 325 2008 ↑ Active
15 Delfi Diagnostics
Provider of DNA sequencing for cancer detection
$331.6M Series B Conventional Debt Dec 2025 197 2019 ↑ Active
16 Orca Bio Unicorn
Developer of Allogeneic cell therapy for cancer, autoimmune diseases and genetic blood disorders
$300M $1B
as of 2020
Series F Series F Jan 2026 66 2016 ↑ Active
17 Parabilis Medicines
Developer of peptide therapeutics for the treatment of severe diseases
$305M Series F Series F Jan 2026 2016 ↑ Active
18 Treeline Biosciences
Developer of transformative precision medicines to treat cancer
$895.4M Series A Series A Aug 2025 148 2021 ↑ Active
19 TEMPEST THERAPEUTICS
Developing targeted, immune-mediated oral cancer therapies for broad patient benefit
$88.2M Public Post IPO Mar 2026 19 2011 ↑ Active
20 Bonum Therapeutics
Manufacturer of cytokine based drugs
$93M Series B Series B Apr 2026 54 2021 ↑ Active
21 LTZ Therapeutics
Developer of immunotherapies to treat cancer and other diseases
$47M Series B Series B May 2026 23 2021 ↑ Active
22 Atavistik
Developer of allosteric therapeutics for precision oncology and rare diseases
$100M Series B Series B Mar 2026 33 2021 ↑ Active
23 Rakuten Medical
Developer of a photoimmunotherapy platform for treating cancer
$874.3M Series F Series F Jul 2025 110 2013 ↑ Active
24 Third Arc Bio
Developer of therapetics for cancer and immunological diseases
$165M Series A Series A Feb 2026 2022 ↑ Active
25 Verismo Therapeutics
Developer of CAR-T cell therapies for cancer
$50M Series A Series A Apr 2026 9 2020 ↑ Active
26 HistoSonics
Ultrasound-based tissue ablation
$315.7M Acquired Series E Oct 2025 56 2009 ↑ Active
27 Crossbow
Developer of antibody therapies for cancer treatment
$80M Series B Series B Mar 2026 24 2021 ↑ Active
28 Moderna
Developer of mRNA-based therapeutics for a wide range of diseases
$2.8B Public Grant (prize money) Jan 2025 1,312 2010 ↑ Active
29 BlossomHill Therapeutics
Provider of the drug for the treatment of oncology and autoimmune disorders
$259.6M Series B Series B Nov 2025 14 2020 ↑ Active
30 OncoSynergy
Developer of resistance mechanism inhibitors to treat cancer
$26.7M Acquired Series A May 2026 3 2011 ↑ Active
31 Artelo Biosciences
Modifying lipid-signaling pathways to improve cancer treatments
$39.9M Public Post IPO Mar 2026 7 2011 ↑ Active
32 TORL BioTherapeutics
Developer of antibody-based therapeutics for the treatment of cancer
$350M Series C Series C Oct 2025 2019 ↑ Active
33 Kanvas Biosciences
Provider of imaging solutions for microbial research and infectious diseases
$29.5M Series A Series A May 2026 10 2021 ↑ Active
34 TRexBio
Developer of therapeutics for immunology and cancer
$85M Series B Series B Jan 2026 65 2019 ↑ Active
35 Vyriad
Developer of oncolytic-virus-based immunotherapies for cancer treatment
$100M Series B Series B Dec 2025 37 2016 ↑ Active
36 Cue Biopharma
Precision immunotherapies to transform patients' lives by selectively modulating the immune system
$26.4M Public Post IPO May 2026 51 2015 ↑ Active
37 Caris Life Sciences Unicorn
Developer of panomic disease profiling technologies for cancer precision medicine
$1.1B $7.8B
as of 2021
Public Series D Apr 2025 1,339 1996 ↑ Active
38 NextCure
Developer of next-generation immuno-oncology-based drugs
$175.4M Public Post IPO Nov 2025 87 2015 ↑ Active
39 Sirnaomics
Developer of RNA based therapeutics for the treatment of cancer and fibrosis disease
$267M Public Post IPO Sep 2025 88 2007 ↑ Active
40 Aprea
Developer of small molecule therapeutics targeting tumor suppressor proteins
$113.2M Public Post IPO Dec 2025 13 2003 ↑ Active
41 Solve Therapeutics
Developer of antibody-based therapies targeting tumor-specific antigens for cancer treatment
$195M Series D Series D Nov 2025 2021 ↑ Active
42 Tango Therapeutics
Developer of drugs for the treatment of cancer
$165M Public Post IPO Oct 2025 140 2017 ↑ Active
43 Athos Therapeutics
Developer of AI-based therapeutics for treating autoimmune diseases
$28M Series A Series A Apr 2026 18 2019 ↑ Active
44 Incyclix Bio
A next-generation cell cycle control company advancing precision treatments for cancer
$30M Series B Series B Apr 2026 6 2020 ↑ Active
45 Lyell Immunopharma
Developer of CAR- T therapy for cancer treatment
$493M Public Post IPO Jul 2025 224 2018 ↑ Active
46 Enveric
Developer of small-molecule therapeutics for the treatment of neuropsychiatric disorders
$26.4M Public Post IPO Apr 2026 25 1994 ↑ Active
47 Primmune Therapeutics
Developer of immunotherapies for treating cancer
$46.8M Series B Series B Jan 2026 9 2017 ↑ Active
48 Odyssey
Developer of immunotherapeutics for immunological and cancer diseases
$503.2M Public Series D Jun 2025 108 2018 ↑ Active
49 CASI Pharmaceuticals
Developer of therapeutics for the treatment of cancer
$69.5M Public Post IPO Dec 2025 234 1991 ↑ Active
50 Agenusbio
Developer of immunotherapies to treat cancer
$440.7M Public Post IPO Jun 2025 533 1994 ↑ Active

Top 12 Oncology companies in United States

#1
GRAIL Public
$2B Raised
expand_more
#1

GRAIL Public

location_onMenlo Park, California
Founded
2016
Employees
491
Funding raised
$2B
Stage
Public

Developer of a screening platform for circulating tumor DNA to detect cancer. The company is developing a test called "Galleri" a pan-cancer screening test by measuring circulating nucleic acids in the blood. Its proprietary platform uses the ultra-deep sequencing technique to measure levels of circulating tumor DNA in the patient's blood.

Funding rounds (5 disclosed of 6)
Round Date Amount
Post IPO Oct 2025 $325M
Series D Nov 2019 $390M
Series C May 2018 $300M
Series B Jun 2017 Undisclosed
Series B Feb 2017 $1.2B
Series A Jan 2016 $100M
Tech stack
amazon cloudfrontamazon s3amazon sesamazon web servicesapolloapple icloud mail+14
#2
Senti Bio Public
$158M Raised
expand_more
#2

Senti Bio Public

location_onSan Francisco, California
Founded
2016
Employees
122
Funding raised
$158M
Stage
Public

Developer of cell and gene therapies for patients living with incurable diseases. The company has developed its proprietary synthetic biology platform to produce cell and gene therapies for cancer treatment. The company's pipeline is comprised of cell therapies engineered with Gene Circuits to target difficult to treat liquid and solid tumors. It offers CAR-NK-based therapies for multiple cancer and tumors.

Funding rounds (8 disclosed of 8)
Round Date Amount
Post IPO May 2026 $40M
Post IPO Dec 2024 $37.6M
Post IPO Dec 2024 $10M
Grant (prize money) Jun 2024 $8M
Series B Jan 2021 $105M
Grant (prize money) Sep 2018 $225K
2 earlier rounds — sign up free
Tech stack
acquia cloud platformacquia cloud site factoryaddthisadobe analyticsadobe experience platform identity serviceadobe experience platform launch+14
#3
Terremoto Series C
$250M Raised
expand_more
#3

Terremoto Series C

location_onSan Francisco, California
Founded
2021
Employees
35
Funding raised
$250M
Stage
Series C

Developer of small-molecule therapeutics for cancer treatment. It provides a lysine-targeted covalency platform to develop therapies against known drug targets for oncology.

Funding rounds (3 disclosed of 3)
Round Date Amount
Series C Apr 2026 $108M
Series B Nov 2023 $175M
Series A May 2022 $75M
Tech stack
all in one seoamazon web servicesapple icloud mailbugherdcdnjscloudflare+14
#4
$206.2M Raised
expand_more
#4

Iambic Therapeutics Series C

location_onSan Diego, California
Founded
2019
Employees
50
Funding raised
$206.2M
Stage
Series C

Provider of AI-driven drug discovery platform for the treatment of cancer. It offers an AI driven discovery platform and has discovered two candidates known as IAM-H1, a highly selective and brain penetrant inhibitor of HER2 and its oncogenic mutants, and IAM-C1 a potential first-in-class selective dual CDK2/4 inhibitor to address unmet needs in terms of therapeutic window and treatment resistance in cell cycle drive

Funding rounds (5 disclosed of 5)
Round Date Amount
Series C Apr 2026 $27.8M
Series C Nov 2025 $100M
Series B Apr 2024 $50M
Series B Oct 2023 $103.2M
Series A Jul 2021 $53M
Tech stack
apple icloud mailcloudflaredocusigngoogle font apigoogle hosted librarieshsts+8
#5
CytoDyn Public
$249.7M Raised
expand_more
#5

CytoDyn Public

location_onVancouver, Washington
Founded
2002
Employees
12
Funding raised
$249.7M
Stage
Public

Developer of humanized monoclonal antibodies for the treatment and prevention of HIV infection. It offers lead candidate, PRO 140,for HIV with demonstrated antiviral activity in men. PRO 140 blocks the HIV co-receptor CCR5 on T-cells that prevent viral entry.

Funding rounds (23 disclosed of 23)
Round Date Amount
Post IPO Mar 2026 $17.5M
Post IPO Jan 2026 $18.6M
Post IPO Apr 2022 $1.9M
Post IPO Dec 2021 $11.4M
Post IPO Apr 2021 $28.5M
Post IPO Nov 2020 $25M
17 earlier rounds — sign up free
Tech stack
amazon web servicesapache http serverapple icloud mailbootstrapfancyboxgoogle analytics+4
#6
$410M Raised
expand_more
#6

Century Therapeutics Public

location_onPhiladelphia, Pennsylvania
Founded
2018
Employees
94
Funding raised
$410M
Stage
Public

Developer of therapeutics for the treatment of autoimmune diseases and cancer. The company's iPSC-derived cell therapy platform that integrates cutting-edge gene editing, protein engineering, technical development and manufacturing capabilities to generate allogeneic, iPSC-derived therapies for autoimmune diseases and cancer.​

Funding rounds (4 disclosed of 4)
Round Date Amount
Post IPO Jan 2026 $135M
Post IPO Apr 2024 $60M
Series C Mar 2021 $160M
Series C Jul 2019 $250M
#7
CREATE Medicines Series B
$122M Raised
expand_more
#7

CREATE Medicines Series B

location_onCambridge, Massachusetts
Founded
2019
Funding raised
$122M
Stage
Series B

Developer of messenger ribonucleic acid therapies for immune cell programming. These therapies utilize lipid nanoparticle delivery systems to modify immune cells directly within the body. The technology targets specific cell types to address conditions related to oncology and autoimmunity. The approach focuses on the expression of chimeric antigen receptors to facilitate immune responses against disease targets.

Funding rounds (1 disclosed of 1)
Round Date Amount
Series B May 2026 $122M
#8
$557.5M Raised
expand_more
#8

Guardant Health Public

location_onRedwood City, California
Founded
2012
Employees
1,351
Funding raised
$557.5M
Stage
Public

Developer of digital sequencing technology for cancer detection. The product Guardant360 offers real-time, biopsy-free tumor sequencing for the analysis and identification of tumor-associated treatment options. Also, it has developed analytical tools, including a tumor response map and a mobile-enabled physician portal.

Funding rounds (7 disclosed of 7)
Round Date Amount
Post IPO Nov 2025 $350M
Post IPO Nov 2020 $1B
Series E Aug 2017 $360M
Series D Jan 2016 $100M
Series C Mar 2015 $56M
Series B Apr 2014 $31.5M
1 earlier round — sign up free
Tech stack
amazon web servicesaosapache http serverapple icloud mailbootstrapbugherd+14
#9
Adela Series A
$108.5M Raised
expand_more
#9

Adela Series A

location_onSan Francisco, California
Founded
2021
Employees
62
Funding raised
$108.5M
Stage
Series A

Developer of a platform for detection of cancer. The company has developed a blood test for genome-wide methylation analysis technology to detect kidney cancer and intracranial brain tumors. It allows distinguishing the informative methylated regions of the genome from non-informative regions and targets for sequencing.

Funding rounds (4 disclosed of 4)
Round Date Amount
Series A Apr 2026 $5M
Series A Jun 2025 $25.4M
Series A Jul 2023 $48.5M
Series A Jun 2021 $60M
#10
Summit Public
$713M Raised
expand_more
#10

Summit Public

location_onMenlo Park, California
Founded
2003
Employees
99
Funding raised
$713M
Stage
Public

Developer of therapeutics for oncology and rare diseases. It offers Ivonescimab which combines the effects of immunotherapy via a blockade of PD-1 with the anti-VEGF effect for the treatment of non-small cell lung cancer.

Funding rounds (4 disclosed of 4)
Round Date Amount
Post IPO Oct 2025 $228M
Post IPO Sep 2024 $235M
Post IPO Jun 2024 $200M
Post IPO Nov 2020 $50M
Founders & key people
Investors
Tech stack
cloudflarefancyboxgodaddygoogle font apihstsjquery+9
#11
$135.7M Raised
expand_more
#11

Precision BioSciences Public

location_onDurham, North Carolina
Founded
2006
Employees
236
Funding raised
$135.7M
Stage
Public

Developer of gene editing therapies to treat rare genetic diseases. The company utilizes novel proprietary ARCUS platform to develop in vivo gene editing therapies for sophisticated gene edits, including gene insertion, excision, and elimination. The company's pipeline include therapies for Hepatitis B, duchenne muscular dystrophy, and more.

Funding rounds (9 disclosed of 9)
Round Date Amount
Post IPO Mar 2026 $7.5M
Post IPO Jun 2022 $75M
Conventional Debt Mar 2019 $39.5M
Series B Jun 2018 $110M
Series A May 2015 $25.6M
Grant (prize money) Dec 2010 $3M
3 earlier rounds — sign up free
Tech stack
acquia cloud platformacquia cloud site factoryadobe analyticsadobe experience platform identity serviceadobe experience platform launchamazon web services+14
#12
ClearNote Health Series D
$70M Raised
expand_more
#12

ClearNote Health Series D

location_onSan Diego, California
Founded
2016
Employees
45
Funding raised
$70M
Stage
Series D

Developer of non-invasive cancer detection methods. It offers a 5-hydroxymethylcytosine-based epigenomic platform and cell-free DNA-based assays to measure biological changes in cells and detect cancers with high mortality rates when they respond best to treatment.

Funding rounds (2 disclosed of 2)
Round Date Amount
Series C May 2025 $21.8M
Series C May 2021 $70M

Recent signals in United States Oncology

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Funding & investor landscape

Total raised
$112.1B
across these companies
Companies funded
1,702
with disclosed funding
Highest-funded
$2.8B raised

Most active investors

H HHS 446 investments in Oncology O Orbimed 87 investments in Oncology RM RA Capital Management 84 investments in Oncology A Alexandria 74 investments in Oncology N NIH 74 investments in Oncology FC Foresite Capital 56 investments in Oncology JI Janus Henderson Investors 53 investments in Oncology NA New Enterprise Associates 53 investments in Oncology J JLABS 51 investments in Oncology BC Boxer Capital 50 investments in Oncology NI Nextech Invest 49 investments in Oncology AP Arch Venture Partners 46 investments in Oncology

Notable founders in United States Oncology

JC Jim Collins Co-Founder Senti Bio · $158M raised
WW Wilson Wong Co-Founder Senti Bio · $158M raised
TL Tim Lu Co-Founder & CEO Senti Bio · $158M raised
MJ Matt Jacobson Co-Founder Terremoto · $250M raised
JT Jack Taunton Co-Founder Terremoto · $250M raised
PT Peter Thompson Co-Founder & CEO Terremoto · $250M raised
FM Fred Manby Co-Founder & CTO Iambic Therapeutics · $206.2M raised
TM Thomas Miller Co-Founder & CEO Iambic Therapeutics · $206.2M raised
DG Daniel Getts Co-Founder & CEO CREATE Medicines · $122M raised
AT Amirali Talasaz Co-founder and Co-Chief Executive Officer Guardant Health · $557.5M raised
MA Manish Agarwal Co-Founder Adela · $108.5M raised
SB Scott Bratman Co-Founder Adela · $108.5M raised

Frequently asked questions

How many Oncology companies are there in United States?
Radar tracks 2665 indexable Oncology companies headquartered in United States, India, that meet our profile-completeness bar.
What is the total funding raised by Oncology companies in United States?
The Oncology companies in United States on this list have raised a combined $112.1B in disclosed equity funding across 1702 funded companies.
Which is the highest-funded Oncology company in United States?
Moderna is the highest-funded Oncology company in United States, with $2.8B in disclosed equity funding.
How many Oncology companies in United States are funded?
1702 of the 2665 Oncology companies in United States on this list have disclosed at least one equity funding round.
How many Oncology unicorns are there in United States?
8 Oncology companies in United States on this list are valued at $1B or more.
Who are the top investors in United States Oncology companies?
The most active investors in United States Oncology companies on this list include HHS, Orbimed, RA Capital Management, Alexandria, NIH.

Rankings are computed by Radar (Fliar BI) from the Radar company master and are updated periodically. Funding and momentum scores use disclosed equity-funding data only. Figures may lag private rounds. Last updated 2026-06-16.

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