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Radar · Regenerative Medicine in United States

Best Regenerative Medicine Companies in United States

The 139 best Regenerative Medicine companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Humacyte.

139companies tracked
$2.7Bdisclosed funding
0unicorns
96have raised

Ranking the best Regenerative Medicine companies in the United States by disclosed equity funding, this directory tracks 139 ventures that have collectively raised $2.7 billion, with not a single unicorn in the mix yet. That last part tells you something. Arsenal Medical leads the field at $70 million raised, followed by Stellular Bio and Epibone at $44 million each, and Healionics at $27 million. The funding is real and it's patient, sourced heavily from HHS, NIH, and America's Seed Fund rather than venture megafunds chasing quick exits. The global market stood at $10.1 billion in 2020 and is forecast to reach $83.2 billion by 2030 at a 21.1% CAGR, driven by chronic disease prevalence and cancer treatment demand. So the capital base here, $2.7 billion across 139 companies, is still early relative to where this sector is heading.

What I'd watch is the regulatory friction. The lack of standardized approval pathways for regenerative drugs remains a structural drag on commercialization timelines, even as hot themes like cell-based therapies and machine learning drug discovery accelerate R&D. Coverage of the space is rising fast, with frontiers in healthcare regenerative medicine drawing wider attention from clinicians and investors alike. The companies in this directory aren't chasing hype. They're building on validated science, grant capital, and a market trajectory that's hard to argue with.

Ranked: Best Regenerative Medicine companies in United States

#CompanyDisclosed fundingLast roundEmployeesFoundedFounderMarket signals (1y)Patents & IP focusRecent signals
1Humacyte
Provider of human tissue-based products for vascular disease
$425M62 mo ago70
70 → 166 (+137%) · sector median +11%
2004Juliana Blum
Co-Founder
13 signals
Earnings · Funding · Capital raise
137 patents
Engineered vascular grafts and medicated implantable matrices for blood vessel replacement.
—
2MiMedx Group
Regenerative biomaterial products and bioimplants for wound, surgical, sports medicine and orthopedics
$213M71 mo ago735
735 → 789 (+7%) · sector median +11%
1985—6 signals ▼40%
Earnings · Leadership
472 patents
Placental-derived collagen wound healing matrices and grafts for tissue repair
1 launch
3Ensoma
Developer of in vivo hematopoietic stem cell engineering for genomic medicine
$205M37 mo ago52
52 → 51 (-2%) · sector median +11%
2019——62 patents
Adenoviral gene‑therapy vectors enabling multi‑lineage therapeutic expression and stem‑cell mobilization
—
4Walking Fish Therapeutics
Developer of cell-based therapeutic solutions for treating cancer & immunological disorders
$123M52 mo ago372019Seenu Kothakota
Co-Founder
———
5Histogenics
Developer of restorative cell therapies for orthopedic diseases
$116M117 mo ago842000——121 patents
Adhesive scaffolds and porous matrices for articular cartilage regeneration.
—
6BioTissue
Developer of regenerative biologic therapies for eye care
$110M60 mo ago234
234 → 372 (+59%) · sector median +11%
2001Amy Tseng
Founder and Board Member
—31 patents
Patents concentrated in health & consumer products
1 job opening
7Satellite Bio
Developer of proprietary implantable satellite organs
$110M51 mo ago21
21 → 24 (+14%) · sector median +11%
2019Arnav Chhabra
Co-Founder
———
8AxoGen
Developer of therapies for the repair of peripheral nerve injuries
$96M115 mo ago809
809 → 607 (-25%) · sector median +11%
2002Karen Zaderej
President
13 signals ▼32%
Earnings · IPO · Acquisition
560 patents
Peripheral nerve repair and regeneration using specialized biomaterial grafts and protective devices
—
9Cerapedics
Developer of Osteobiologic products
$88M95 mo ago31996Valeska Schroeder
CEO
—49 patents
Bioactive peptide-coated calcium‑phosphate coatings for orthopedic implants reducing inflammation
1 launch
10Arsenal Medical
Developer of polymer-based foams and fibers
45Funding top 20%Talent top 23%Product top 26%Moat top 26%
All 10 signals ▾
Fundingtop 20%
Talenttop 23%
Producttop 26%
Moattop 26%
Patentstop 27%
Innovationtop 35%
Techbottom 39%
Globalbottom 38%
Marketbottom 26%
Newsbottom 22%
Funding: Raised $69.9M across 21 rounds · 21 rounds over 21 yrs (1.0/yr)
Talent: 5 named leaders on record · 5 C-suite/founder profiles curated
rank vs industry peers · Fliar Intelligence Index 45/100
$70M10 mo ago16
16 → 29 (+81%) · sector median +11%
2005Eric Stern
Co-Founder & CTO
—190 patents
Hemostatic and embolic biomaterial devices for bleeding control and vascular occlusion.
—
11CorMatrix
Cardiovascular regeneration leader, healing hearts with innovative solutions
$55M58 mo ago502001————
12Augmenix
Provider of a hydrogel spacer for prostate cancer radiation therapy
$47M119 mo ago153
153 → 100 (-35%) · sector median +11%
2008————
13LoneStar Heart
Cardiac therapies for patients with Chronic Heart Failure
$45M110 mo ago22010Frank Ahmann
CEO & President
———
14LifeSprout
Developing revolutionary products for aesthetic and regenerative medicine
$45M74 mo ago12
12 → 20 (+67%) · sector median +11%
2015Justin Sacks
Co-Founder
—14 patents
Collagen‑hydrogel composites for soft‑tissue augmentation and fat grafting applications
—
15Stellular Bio
Developer of a platform for producing allogeneic, stem-cell-derived platelet-like cells
37Funding top 28%Talent top 28%Moat bottom 38%Global bottom 37%
All 5 signals ▾
Fundingtop 28%
Talenttop 28%
Moatbottom 38%
Globalbottom 37%
Marketbottom 32%
Funding: Raised $44.5M across 9 rounds · 9 rounds over 10 yrs (0.9/yr)
Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
rank vs industry peers · Fliar Intelligence Index 37/100
$44M4 mo ago122014Joseph Italiano
Co-Founder
———
16Epibone
Developer of patient‑specific bone and cartilage grafts
50Moat top 25%Talent top 28%Funding top 29%Patents top 32%
All 9 signals ▾
Moattop 25%
Talenttop 28%
Fundingtop 29%
Patentstop 32%
Innovationtop 38%
Techtop 46%
Globalbottom 42%
Marketbottom 31%
Newsbottom 21%
Moat: Editorial + unicorn rating 7/10 · IP moat: 48 patents
Talent: 4 named leaders on record · 4 C-suite/founder profiles curated
rank vs industry peers · Fliar Intelligence Index 50/100
$44M9 mo ago342013Elisa Cimetta
Co-Founder
—48 patents
Regenerative orthopedic biomaterials for injectable cartilage/tendon/ligament repair and surgical tools.
—
17Carbylan
Therapeutics using polymers of hyaluronic acid for pain management.
$43M135 mo ago72004————
18PolarityTE
Developer of regenerative medicine
$42M25 mo ago371998——63 patents
Patents concentrated in chemistry & materials
—
19Imagine Pharma
Developing polypeptide therapeutic drugs for treating cardiovacular disorders
$40M31 mo ago122016————
20Tepha
Global medical technology company advancing healthcare through innovative solutions and services
$40M171 mo ago511998——627 patents
Resorbable polymer medical implants and devices for surgery and aesthetic reconstruction
—
21Solsys Medical
Provider of human skin allograft and dressing for wound care
$37M103 mo ago801999Guy Levy
Co-Founder & CSO
———
22Embody
Provider of collagen-based regenerative matrices for soft tissue repair
$36M45 mo ago252014Michael Francis
Co-Founder
—133 patents
Advanced collagen-based scaffolds and delivery devices for surgical implants and tissue engineering
—
23Triad Life Sciences
Developer of regenerative medicine technologies
$32M57 mo ago332017————
24Organogenesis
Regenerative tissue innovations for advanced wound care and surgical solutions
$30M19 mo ago856
856 → 921 (+8%) · sector median +11%
1985Gary Gillheeney
CEO
7 signals ▼73%
Earnings
209 patents
Collagen-based biomaterials for wound healing, tissue regeneration, and anti‑inflammatory assay kits.
—
25Healionics
Manufacturer of synthetic biomaterials and implantable medical devices
27Talent top 15%Moat top 25%Funding top 35%Patents top 42%
All 9 signals ▾
Talenttop 15%
Moattop 25%
Fundingtop 35%
Patentstop 42%
Innovationbottom 47%
Globalbottom 40%
Techbottom 32%
Marketbottom 20%
Newsbottom 18%
Talent: Analyst team rating 5/5
Moat: Editorial + unicorn rating 7/10 · IP moat: 42 patents
rank vs industry peers · Fliar Intelligence Index 27/100
$27M6 mo ago102007——42 patents
Implantable vascular grafts and porous ocular drug‑delivery devices for eye disease treatment
—
26RevBio
Developer of synthetic adhesive used for bone/dental repair
57Talent top 23%Innovation top 28%Patents top 28%Funding top 34%
All 7 signals ▾
Talenttop 23%
Innovationtop 28%
Patentstop 28%
Fundingtop 34%
Moattop 38%
Marketbottom 37%
Globalbottom 31%
Talent: 5 named leaders on record · 5 C-suite/founder profiles curated
Innovation: 50 patents (top 31% of patent-holders) · 44 filings since 2022 vs 6 in 2017-21
rank vs industry peers · Fliar Intelligence Index 57/100
$24M12 mo ago292014Michael Brown
Co-Founder
—50 patents
Biomedical adhesives and bone fixation devices for controlled drug delivery
—
27Artelon
Developer of regenerative medicine for the soft tendon ligament reconstruction
$20M36 mo ago721986Lars Peterson
Founder
———
28Carmell
Biotech company specializing in the development of plasma-based bioactive materials for tissue repair.
$20M71 mo ago72007Rajiv Shukla
CEO
—2 patents
Plasma-assisted synthesis of specialty plastics and biodegradable polymers
—
29Royal Biologics
Innovating orthobiologics and wound care solutions for enhanced healing
$20M16 mo ago162015Salvatore Leo
CEO
—14 patents
Autologous bone graft enhancement and marrow-derived cell/fluid separation technologies.
2 launchs
30Sofregen
Natural biomaterials for soft tissue regeneration in aesthetic and surgical procedures
$19M81 mo ago82014Anh Hoang
Co-Founder & CSO
———
31Vascudyne
Developer of regenerative biomaterials for tissue repair and replacement
$18M13 mo ago62014Jeff Franco
Co-Founder
—40 patents
Engineered tissue implants for cardiovascular valves, grafts, and nerve repair
1 award
32Dimension Inx
Provider of 3D bio materials for regenerative medicine
$18M40 mo ago272017Ramille Shah
Co-Founder & CSO
—12 patents
3D-printed self-gelling biomaterials for implantable cell-encapsulation devices.
1 internship
33GeniPhys
Developer of collagen polymers for tissue regeneration
$10M4 mo ago42014——18 patents
Collagen-based biologic fillers for tissue regeneration and high-strength matrix scaffolds.
—
34Gel4Med
Bioinspired medical solutions company developing advanced biomaterials for unmet clinical needs
$10M14 mo ago42015——40 patents
Peptide-based self‑assembling hydrogels for regenerative medicine and targeted drug/cell delivery
1 partnership
35Ventrix
Developer of extracellular matrix-based therapeutics for cardiac diseases
$6M33 mo ago22009Karen Christman
Co-Founder
—18 patents
Cardiac therapeutic compositions and delivery methods for heart disease treatment
—
36Jellatech
Provider of animal-free collagen and gelatin products for multiple industries
$6M33 mo ago72020Stephanie Michelsen
Co-Founder & CEO
—10 patents
Cell‑cultured collagen/gelatin production for biomedical and cosmetic material manufacturing.
—
37Halo Biosciences
Developer of therapies by editing extracellular matrix
$5M14 mo ago122019Andy Wardle
Co-Founder & Advisor
———
38BioDevek
Developer of next generation of surgical sealant solutions
$5M10 mo ago32014Elazer Edelman
Co-Founder
—15 patents
Biocompatible medical adhesives for tissue bonding and wound closure
—
39GelSana
Developer of novel hydrogels for wound healing
$4M11 mo ago22020Melissa Krebs
Founder & CEO
——1 partnership
40Inovedis
Developer of surgical implants for tendon healing
$4M32 mo ago—2019Stefan Welte
Co-Founder & Co-CEO
———
41Lynch Biologics
Developer of regenerative medicines for orthopaedic, periodontal and oral treatments
$4M29 mo ago92015Sam Lynch
Founder & CEO
———
42Bluegrass Advanced Materials
Antioxidant polymers based therapy for the treatment of oral mucositis
$4M14 mo ago22013Thomas Dziubla
Co-Founder
———
43inSoma Bio
Provider of protein-based biomaterials for tissue engineering and regenerative medicine
$3M6 mo ago62018Stefan Roberts
Co-Founder & CEO
———
44Deverra Therapeutics
Provider of progenitor blood and immune cells for clinical application
$2M33 mo ago132020Colleen Delaney
Founder
———
45BioStem Technologies
Provider of placental-based amniotic tissue products
$2M31 mo ago102006Andrew VanVurst
Co-Founder
9 signals ▼36%
Earnings · Leadership · Acquisition
7 patents
Regenerative biomaterials from human umbilical cord and placental tissue for therapeutic applications
—
46Chromocell
Uses rare cells suited for effective high-throughput screening
$950K22 mo ago42002Christian Kopfli
CEO
—318 patents
Fluorogenic oligo cell‑engineering assays and sweet‑taste/sodium‑channel therapeutic modulators
—
47TYBR Health
Provider of regenrative medicine for post surgical scarring
$835K17 mo ago72020Alex Smith
Co-Founder
——1 launch
48LambdaVision
Provider of a protein-based retinal prosthesis for retinal degenerative diseases
$650K7 mo ago72009——6 patents
Retinal cell stimulation therapies for vision restoration
1 partnership
49PRO Therapeutics
Developer of regenerative medicine for orthopedic diseases
$477K6 mo ago—2023Julie Lenzer
CEO
———
50Plakous Therapeutics
Developer of regenerative therapies from the placenta
$310K16 mo ago62016Seth Tomblyn
Co-Founder
———

Top 12 Regenerative Medicine companies in United States

#1
Series A · Watertown, Massachusetts · founded 2014 · 12 employees
$44.5Mraised
▾

Developer of a platform for producing allogeneic, stem-cell-derived platelet-like cells. It offers programmable logic controller platform focused on modifying the regenerative power of platelets, enabling researchers to create reengineering cell therapies.

Fliar Intelligence Index™ 37how this company ranks against its industry peers
Funding
top 28%
Talent
top 28%
Moat
bottom 38%
Global
bottom 37%
Market
bottom 32%
Funding: Raised $44.5M across 9 rounds · 9 rounds over 10 yrs (0.9/yr) · Last round Series A (Jan 2026)
Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
Moat: Editorial + unicorn rating 1/10 · 9 curated direct competitors tracked
Audience (LinkedIn): 883 LinkedIn followers
Funding rounds
  • Jan 2026Series A—
  • Mar 2025Grant (prize money)$356.5K
  • Aug 2019Series A$26.4M
  • May 2017Series A$10M
Founders & team
Joseph ItalianoCo-FounderJonathan ThonFounderDerek AdamsCEO & President
Investors
HHS, BioSciKin, National Heart Lung and Blood Institute, Vivo Capital, Nest Bio Ventures, Cockrell Interests
#2
Series C · Seattle, Washington · founded 2007 · 10 employees
$26.6Mraised
▾

Healionics is a manufacturer of synthetic biomaterials and implantable medical devices. It provides tissue regeneration and device bio integration solutions to medical device manufacturers. It offers sphere-templated angiogenic regeneration (STAR) technology, which provides substrate independent, precision-engineered, and 3D biomaterial scaffolds that enhance the bio-integration and promote healing of implanted medical devices. The company’s products are used in various areas, including wound care, aesthetic medicine, cardiovascular surgery, diabetes, general surgery, ophthalmology, pain management, regenerative medicine, and urological/women's health.

Fliar Intelligence Index™ 27how this company ranks against its industry peers
Talent
top 15%
Moat
top 25%
Funding
top 35%
Patents
top 42%
Innovation
bottom 47%
Global
bottom 40%
Talent: Analyst team rating 5/5
Moat: Editorial + unicorn rating 7/10 · IP moat: 42 patents
Funding: Raised $26.6M across 18 rounds · 18 rounds over 18 yrs (1.0/yr) · Last round Series C (Dec 2025)
Audience (LinkedIn): 724 LinkedIn followers
Funding rounds
  • Dec 2025Series C$2M
  • Apr 2024Grant (prize money)$953.4K
  • Oct 2023Series C$5.5M
  • May 2021Series C$5.5M
Investors
Keiretsu Capital, Bellingham Angel Group, Alliance of Angels, Tacoma Angel Network, ZINO Society, Keiretsu Forum
Tech stack
WordpressMysqlPhpContact Form 7Yoast SeoNginx
#3
Series D · Waltham, Massachusetts · founded 2005 · 16 employees
$69.9Mraised
▾

Arsenal Medical is developing polymer-based foams and fibers. The company is developing a system that injects an in-situ curing elastomeric polymer material that fills and seals the aneurysm sac around a stent-graft.

Fliar Intelligence Index™ 45how this company ranks against its industry peers
Funding
top 20%
Talent
top 23%
Product
top 26%
Moat
top 26%
Patents
top 27%
Innovation
top 35%
Funding: Raised $69.9M across 21 rounds · 21 rounds over 21 yrs (1.0/yr) · Last round Grant (prize money) (Jul 2025)
Talent: 5 named leaders on record · 5 C-suite/founder profiles curated
Product: 3 distinct product lines · Company stage: Series D
Audience (LinkedIn): 2k LinkedIn followers
Activity (LinkedIn): 1 awards announced in 12 mo
Funding rounds
  • Jul 2025Grant (prize money)$314.4K
  • May 2021Grant (prize money)$1.9M
  • Jul 2020Grant (prize money)$367.2K
  • Jun 2019Series D$6M
Founders & team
Eric SternCo-Founder & CTOGeorge WhitesidesCo-FounderRobert LangerCo-Founder
Investors
Intersouth Partners, Polaris Partners, North Bridge Venture Partners, HHS, National Oceanic and Atmospheric Administration, Springboard Enterprises
Tech stack
CloudflareCloudflare Bot ManagementGoogle AnalyticsGoogle Font ApiIsotopeJplayer
#4
Series A · Zionsville, Indiana · founded 2014 · 4 employees
$10.5Mraised
▾

Developer of collagen polymers for tissue regeneration. It offers Collymer a polymerizable scaffold-forming collagen that supports tissue restoration and regeneration. It is used in cartilage replacement, vascular grafts, and heart valve replacement, and others.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 469 LinkedIn followers
Activity: 1 partnerships (incl. GeniPhys) announced in 12 mo
Funding rounds
  • Jan 2026Series A$3M
  • Oct 2024Grant (prize money)$500K
  • Mar 2023Series A$6M
  • Nov 2022Series A$4.5M
Investors
Pier 70 Ventures, Elevate Ventures, America’s Seed Fund, Purdue Foundry, Plug and Play Tech Center
#5
Series B · Brooklyn, New York · founded 2013 · 34 employees
$44.3Mraised
▾

Developer of patient‑specific bone and cartilage grafts. The company is offering custom‑shaped, living bone grafts engineered from a patient’s adipose‑derived mesenchymal stem cells and a CT scan of the defect. These are intended for complex bone‑reconstruction cases such as facial, craniofacial, or other skeletal defects.

Fliar Intelligence Index™ 50how this company ranks against its industry peers
Moat
top 25%
Talent
top 28%
Funding
top 29%
Patents
top 32%
Innovation
top 38%
Tech
top 46%
Moat: Editorial + unicorn rating 7/10 · IP moat: 48 patents
Talent: 4 named leaders on record · 4 C-suite/founder profiles curated
Funding: Raised $44.3M across 7 rounds · 7 rounds over 12 yrs (0.6/yr) · Last round Series B (Sep 2025)
Funding rounds
  • Sep 2025Series B$4.3M
  • Nov 2024Series B—
  • Dec 2022Series B$18.5M
  • Nov 2021Series B$1M
Founders & team
Elisa CimettaCo-FounderSarindr BhumiratanaCo-Founder & CSOSidney EisigCo-Founder
Investors
Hackensack Meridian Health, Kendall Capital Partners, LifeSpan Vision Ventures, EMV Capital, NetScientific, Plum Alley Investments
Tech stack
Amazon S3Amazon Web ServicesAngularApache Http ServerBootstrapCart Functionality
#6
Series B · Lowell, Massachusetts · founded 2014 · 29 employees
$24.4Mraised
▾

Developer of synthetic adhesive used for bone/dental repair. The company's proprietary technology includes Tetranite that is a bio-engineered protein derived from worms. The company's product can be used in implant stabilization, fracture repair, spine fusion, dental bone grafting, joint reconstruction, and cranial flap fixation.

Fliar Intelligence Index™ 57how this company ranks against its industry peers
Talent
top 23%
Innovation
top 28%
Patents
top 28%
Funding
top 34%
Moat
top 38%
Market
bottom 37%
Talent: 5 named leaders on record · 5 C-suite/founder profiles curated
Innovation: 50 patents (top 31% of patent-holders) · 44 filings since 2022 vs 6 in 2017-21
Patents: 50 patents matched (strict assignee match) · 44 filings since 2022 vs 6 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 4k LinkedIn followers
Funding rounds
  • May 2025Grant (prize money)$2M
  • Sep 2024Grant (prize money)$1.7M
  • Oct 2023Grant (prize money)—
  • Sep 2023Grant (prize money)$3M
Founders & team
Michael BrownCo-FounderBrian HessCo-Founder & CEOJonathan SlotkinCo-Founder
Investors
NIH, MassChallenge, University of Pittsburgh, Pacific Dental Services, HHS
#7
Seed · Durham, North Carolina · founded 2018 · 6 employees
$2.8Mraised
▾

Provider of protein-based biomaterials for tissue engineering and regenerative medicine. The company offers genetically engineer protein-based materials that can mimic the naturally found elastin found in extracellular. The company's proprietary protein biomatrices known as Fractomers contain bio-active sequences that are thermo-responsive.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 688 LinkedIn followers
Funding rounds
  • Nov 2025Grant (prize money)$2M
  • Sep 2025Seed$1.9M
  • Sep 2024Grant (prize money)$294K
  • Aug 2024Grant (prize money)$296.2K
Founders & team
Stefan RobertsCo-Founder & CEOScott HollenbeckCo-FounderAshutosh ChilkotiCo-Founder & Chairman
Investors
Y Combinator, America’s Seed Fund, HHS, Pourdad Capital, Deep Ventures, Oriza Ventures
Tech stack
Cookie NoticeGodaddyGoogle Font ApiGoogle Hosted LibrariesGoogle WorkspaceJquery
#8
Series A · Stillwater, Minnesota · founded 2014 · 6 employees
$17.7Mraised
▾

Developer of regenerative biomaterials for tissue repair and replacement. The company uses a proprietary Tissue technology platform to develop soft tissue implants and medical devices such as vascular graft for hemodialysis access.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 1k LinkedIn followers
Activity: 1 awards announced in 12 mo
Funding rounds
  • May 2025Grant (prize money)—
  • Oct 2021Series A$17.7M
Founders & team
Jeff FrancoCo-Founder
Investors
Military Health
#9
Funding Raised · Boston, Massachusetts · founded 2014 · 3 employees
$4.6Mraised
▾

Developer of next generation of surgical sealant solutions. The company uses a biodegradable and biocompatible adhesive material platform to develop surgical sealants. It is used to prevent leakage of body fluids from the suture line, such as blood following vascular surgeries and other minimally invasive surgeries.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 2k LinkedIn followers
Hiring: 1 hiring post in 12 mo (public) · hiring: polymer scientist
Funding rounds
  • Aug 2025Grant (prize money)$2.1M
  • Apr 2025Grant (prize money)$1.2M
  • Jun 2024Grant (prize money)$978K
  • Dec 2023Grant (prize money)$275K
Founders & team
Elazer EdelmanCo-Founder
Investors
MedTech Innovator, HHS, National Science Foundation
#10
Funding Raised · Boston, Massachusetts · founded 2015 · 4 employees
$10.1Mraised
▾

Bioinspired medical solutions company developing advanced biomaterials for unmet clinical needs. This is a commercial-stage company focused on shaping the future of medicine by harnessing the power of smart materials to address significant medical challenges. Utilizing bioinspiration and materials engineering, the company has developed a Smart Materials Platform for creating therapeutics and devices. Their lead asset targets wound care and surgical reconstruction. Committed to enhancing health outcomes and access for all patients, they develop novel biomaterials. The proprietary Smart Materials Platform is an innovative bioengineering approach for addressing a wide range of clinical needs. They collaborate and innovate around novel treatments. The company focuses on research and development to create advanced medical solutions.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 5k LinkedIn followers — 2.0% of this cohort's audience
Activity: 1 partnerships (incl. CAMC clinicians) announced in 12 mo
Funding rounds
  • Apr 2025Grant (prize money)$1.2M
  • Sep 2023Grant (prize money)$2.6M
  • Aug 2020Grant (prize money)$300K
  • Jul 2020Grant (prize money)$409.7K
Investors
Breakout Labs, America’s Seed Fund, UMass Lowell, HHS
Tech stack
WixReactGoogle CloudPolyfillLodashSectigo
#11
Series A · Aurora, Colorado · founded 2020 · 2 employees
$4.2Mraised
▾

Developer of novel hydrogels for wound healing. The company has developed the first bio-inert adhesive hydrogel delivery system that offers controlled delivery of therapeutics to promote healing and accelerate wound closure while avoiding unwanted inflammatory responses.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 1k LinkedIn followers
Activity: 1 product launches · 1 partnerships · 1 awards (incl. Juvo Medical) announced in 12 mo
Funding rounds
  • Jul 2025Grant (prize money)$299.6K
  • Sep 2024Grant (prize money)$325K
  • Nov 2023Series A$3.5M
  • Apr 2023Grant (prize money)$299.6K
Founders & team
Melissa KrebsFounder & CEO
Investors
CBSA, Innosphere Ventures, Mines, HHS, Plug and Play Tech Center
Tech stack
Apache Http ServerBlocksyBlocksy CompanionCore-JsDreamhostGoogle Analytics
#12
Public · Canton, Massachusetts · founded 1985 · 856 employees
$30Mraised
▾

Regenerative tissue innovations for advanced wound care and surgical solutions. We are dedicated to empowering healing through regenerative medicine. Our focus lies in delivering clinicians a comprehensive range of regenerative tissue innovations and essential services. We specialize in advanced wound care and surgical & sports medicine solutions. We are committed to elevating the standard of care by providing transformative solutions. Our offerings include products like PuraPly and Affinity, alongside patient and provider support programs. We focus on innovation and regenerative solutions. We provide resources and support to healthcare professionals, ensuring they have access to the most advanced regenerative solutions available. We are committed to corporate social responsibility, ethics, and quality systems.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 35k LinkedIn followers — 14.2% of this cohort's audience
Funding rounds
  • Nov 2024Post IPO$130M
  • May 2017Conventional Debt$20M
  • Apr 2016Series C$30M
  • Jan 2009Grant (prize money)$7.4M
Founders & team
Gary GillheeneyCEO
Investors
Eastward Capital Partners, Massachusetts Life Sciences Center, Innovation Depot, Spring St. Group
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAddthisAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform Launch

Funding & investor landscape

$2.7Btotal disclosed funding
97companies funded
458disclosed rounds
0rounds last 90 days
Most active investors
HHS29 rounds
National Science Foundation6 rounds
America’s Seed Fund5 rounds
Military Health5 rounds
NIH4 rounds
Polaris Partners4 rounds
Alumni Ventures3 rounds
Catalio Capital Management3 rounds
EW Healthcare Partners3 rounds
JAM Capital Partners3 rounds

Notable founders

Joseph Italiano
Co-Founder · Stellular Bio
Jonathan Thon
Founder · Stellular Bio
Eric Stern
Co-Founder & CTO · Arsenal Medical
George Whitesides
Co-Founder · Arsenal Medical
Elisa Cimetta
Co-Founder · Epibone
Sarindr Bhumiratana
Co-Founder & CSO · Epibone
Michael Brown
Co-Founder · RevBio
Brian Hess
Co-Founder & CEO · RevBio
Stefan Roberts
Co-Founder & CEO · inSoma Bio
Scott Hollenbeck
Co-Founder · inSoma Bio
Jeff Franco
Co-Founder · Vascudyne
Elazer Edelman
Co-Founder · BioDevek
Prism market signals · United States · country-scoped Prism corpus, 11,347,227 docs

Market landscape — 10 sub-themes by coverage

Share of Regenerative Medicine coverage by sub-theme.

Regulatory-risk over time flat

Funding & growth over time

funding rising · growth flat

RESEARCH SIGNALS · United States

How research on Regenerative Medicine is moving in the United States

A read on the academic research around Regenerative Medicine — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 10,806 United States-affiliated papers.

research sentiment over time
200820172026
enthusiastic · positive · guarded tone
Tone is overwhelmingly optimistic and softening — the enthusiastic (strongly-positive) share moved 86% → 74% across 2008–2026.
top research entities
  • Harvard University661
  • Brigham and Women's Hospital303
  • Stanford University282
  • Heidelberg University240
  • Johns Hopkins University233
leading researchers
Jason A. Burdick · Freederia AI Researcher · Anthony Atala · Yu Shrike Zhang · Christopher Zdyrski · David L. Kaplan · Su Ryon Shin · Sarah C. Heilshorn
▲ Breakthroughs4,102 · 38%
▲ 29%→39% share
▲1.3× share momentum2 median citations89% since 2021mostly methods-led
Organoid research is surging — breakthrough-tagged papers rocketed from 21 to 1,370, now anchoring 39% of the field.
rising sub-themes (early→recent)
  • Organoid21→1370
  • Tissue engineering136→715
  • Cell biology64→599
  • Self-healing hydrogels69→439
  • Induced pluripotent stem cell40→392
Newly emergingCancer 0→113 · Colorectal cancer 0→49 · Breast cancer 0→43
Landmark Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer · 2,400 cites
◆ Advancements4,421 · 41%
▲ 40%→41% share
▲1.0× share momentum4 median citations88% since 2021mostly empirical
Tissue engineering advancements are intensifying — U.S. papers climbed from 199 to 947 within the advancements segment.
rising sub-themes (early→recent)
  • Organoid10→984
  • Tissue engineering199→947
  • Regeneration (biology)66→544
  • Stem cell92→524
  • Biomedical engineering87→513
Newly emergingColorectal cancer 0→75 · Internal medicine 0→73 · Pancreatic cancer 0→55
Landmark Hydrogels as extracellular matrix mimics for 3D cell culture · 2,655 cites
▼ Concerns1,281 · 12%
▼ 17%→11% share
▼0.6× share momentum8 median citations81% since 2021mostly reviews
Concern-flagged research is shrinking — field-share dropped from 17% to 11% despite organoid concern papers rising 2 to 226.
rising sub-themes (early→recent)
  • Organoid2→226
  • Tissue engineering96→275
  • Regeneration (biology)35→214
  • Stem cell42→210
  • Induced pluripotent stem cell11→108
Newly emergingPrecision medicine 0→23 · Cancer 0→21 · Personalized medicine 0→21
Landmark Advances in engineering hydrogels · 2,714 cites
RESEARCH HOTSPOTS · United States

Where regenerative medicine is researched across United States

Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.

Boston1060 · +0.58
Hot · Tissue engineeringAdvancing · NanotechnologyOpportunity · Human brainConcern · Nanomedicine
New York604 · +0.57
Hot · OrganoidAdvancing · ToughnessOpportunity · TranscriptomeConcern · Engineering ethics
SF Bay Area494 · +0.57
Hot · Image stitchingAdvancing · Notch signaling pathwayOpportunity · Immune systemConcern · Wound healing
Philadelphia322 · +0.57
Hot · Papillary thyroid cancerAdvancing · Circadian rhythmOpportunity · Progenitor cellConcern · Function (biology)
Los Angeles274 · +0.59
Hot · DNA methylationAdvancing · BiopsyOpportunity · Cancer researchConcern · Biocompatible material
Chicago255 · +0.60
Hot · PeptideAdvancing · NanofiberOpportunity · Internal medicineConcern · Tissue repair
Ann Arbor244 · +0.54
Hot · DentistryAdvancing · Peripheral nerveOpportunity · NeuroscienceConcern · Periodontium
Pittsburgh232 · +0.58
Hot · CiliumAdvancing · MotilityOpportunity · BiofabricationConcern · Risk analysis (engineering)
San Diego219 · +0.52
Hot · Crohn's diseaseAdvancing · BiobankOpportunity · CancerConcern · Clinical trial
Atlanta210 · +0.55
Hot · AdhesiveAdvancing · Lymphatic systemOpportunity · Computational biologyConcern · Inflammation
PATENT SIGNAL · United States

Who's filing regenerative medicine patents in the United States

United States regenerative medicine patent filing is accelerating — 1,261 filings from 739 assignees (2016–2025), led by Childrens Hospital MED CT, UNIV WAKE Forest Health Sciences, BIO2 Technologies; annual filings 63→189.

1,261 filings739 assigneespeak 189/yr2016–2025
filing momentum (YoY 2016–2025)
top patent filers
  • Childrens Hospital MED CT138
  • UNIV WAKE Forest Health Sciences62
  • BIO2 Technologies53
  • UNIV Columbia44
  • UNIV California44
  • UNIV Leland Stanford Junior42
  • UNIV Rutgers40
  • UNIV RICE William M37

Common questions

How many Regenerative Medicine companies are there in United States?
Radar tracks 139 indexable Regenerative Medicine companies headquartered in United States that meet our profile-completeness bar.
What is the total funding raised by Regenerative Medicine companies in United States?
The Regenerative Medicine companies in United States on this list have raised a combined $2.7B in disclosed equity funding across 97 funded companies.
Which is the highest-funded Regenerative Medicine company in United States?
Humacyte is the highest-funded Regenerative Medicine company in United States, with $424.8M in disclosed equity funding.
How many Regenerative Medicine companies in United States are funded?
97 of the 139 Regenerative Medicine companies in United States on this list have disclosed at least one equity funding round.
How many Regenerative Medicine unicorns are there in United States?
None of the Regenerative Medicine companies in United States on this list currently has a disclosed valuation of $1B or more.
Who are the top investors in United States Regenerative Medicine companies?
The most active investors in United States Regenerative Medicine companies on this list include HHS, National Science Foundation, America’s Seed Fund, Military Health, NIH.
Riya SenguptaFinancials

Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.

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