Best Sustainability Tech Companies in Baltimore, United States
The 39 best Sustainability Tech companies in Baltimore, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Apkudo.
Our analysis of 84 Sustainability Tech companies
$19.4b in tracked funding; 85% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Sustainability Tech companies in Baltimore
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Apkudo Offers automated tools for operational planning and analytics for the e-waste industry | $75M | 43 mo ago | 74 | Josh Matthews Co-Founder & CEO | WebflowApple iCloud MailAmazon Web Services+15 | Top 10M | 43 patents Cross-device mobile app testing, carrier configuration, and touch-screen UX analytics. | — |
| 2 | Scanogen Provider of single-molecule biosensors for cancer diagnostics 29Talent top 28%Moat top 32%Funding top 33%Patents top 35% All 9 signals ▾Talenttop 28% Moattop 32% Fundingtop 33% Patentstop 35% Innovationtop 42% Productbottom 44% Globalbottom 35% Techbottom 28% Marketbottom 21% Talent: Analyst team rating 4/5 Moat: Editorial + unicorn rating 4/10 · IP moat: 26 patents rank vs industry peers · Fliar Intelligence Index 29/100 | $29M | 13 mo ago | 7 | — | BootstrapApache HTTP ServerCloudflare+7 | Top 10M | 26 patents Optical biosensor and imaging technologies for rapid analyte detection and quantification. | — |
| 3 | Profectus BioSciences Using proprietary discovery engine to develop vaccines against viral infectious diseases and their associated… | $19M | 124 mo ago | 3 | — | — | — | 41 patents Engineered Isfahan viral vectors for gene therapy and recombinant protein production | — |
| 4 | PathoVax Prophylactic vaccine against all 15 oncogenic human papillomavirus. | $10M | 76 mo ago | 3 | Travis Stiles Co-Founder and Interim CEO | — | — | 11 patents Design of chimeric virus-like particle platforms for targeted vaccine and immunotherapy applications | — |
| 5 | Zero Point Five Therapeutics Developer of therapeutics for infectious diseases | $7M | 17 mo ago | — | Joseph Amprey Co-Founder & CEO | — | — | — | — |
| 6 | AccelevirDx Developer of diagnostic assays for HIV | $7M | 17 mo ago | 8 | Albine Martin Co-Founder/Investor | WordPressMySQLPHP+22 | Top 50M | — | — |
| 7 | Pearl Diagnostics Foundation focused on detection and prevention of fungal infections 13Funding top 35%Talent bottom 49%Global bottom 32%Market bottom 20% All 4 signals ▾Fundingtop 35% Talentbottom 49% Globalbottom 32% Marketbottom 20% Funding: Raised $3.5M across 5 rounds · 5 rounds over 4 yrs (1.2/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 13/100 | $4M | 5 mo ago | 6 | Kieren Marr Founder & CEO | — | — | — | — |
| 8 | Astek Diagnostics Manufacturer of blood test diagnostic device | $3M | 29 mo ago | 8 | — | Node.jsFirebaseVuetify+7 | Top 50M | — | — |
| 9 | EDAC Labs Electrochemical production company focused on decarbonization | $3M | 36 mo ago | 3 | Brian Toll Co-Founder | — | — | 3 patents Advanced electrolyzer designs and confined-electrolyte electrochemical cell technologies. | — |
| 10 | Baltimore Regional Housing Partnership Developer of affordable houses | $3M | 51 mo ago | 39 | — | WordPress Block EditorWordPressMySQL+17 | Top 5M | — | — |
| 11 | ThermoChem Recovery International Technology developer for bioenergy projects | $597K | 16 mo ago | 14 | Dan Burciaga President & CEO | — | — | 223 patents Patents concentrated in chemistry & materials | — |
| 12 | Pataigin Assays to identify pathogens using mass spectrometry | $555K | 37 mo ago | — | Erik Nilsson CEO | — | — | 7 patents Patents concentrated in chemistry & materials | — |
| 13 | Drizzle Developer of diagnostic kits for the detections & identification of Tuberculosis | $500K | 21 mo ago | 3 | — | — | — | — | — |
| 14 | Fyodor Biotechnologies Developer of rapid diagnostic kits for infectious disease | $345K | 109 mo ago | 1 | Eddy Agbo CEO & Chairman | — | — | — | — |
| 15 | Jubilee Baltimore Developer of affordable and market-rate housing, commercial properties, and community plans | $213K | 185 mo ago | — | — | — | — | — | — |
| 16 | Manta Biofuel Manufactures biofuels from algal biomass | $150K | 116 mo ago | 10 | — | — | — | 4 patents Algae harvesting and processing systems for biofuel production | — |
| 17 | AlgenAir Online retailer of microalgae-based air purification systems and refill products | $100K | 46 mo ago | 3 | Daniel Fucich Co-Founder & CSO | Cart FunctionalityShopifySentry+38 | Top 10M | 3 patents Algae-based photobioreactor systems for indoor air purification and quality improvement. | — |
Top 12 Sustainability Tech companies in Baltimore
#1
Funding Raised · Baltimore, Maryland · founded 2011 · 7 employees$28.6Mraised▾
Provider of single-molecule biosensors for cancer diagnostics. The company's semiconductor-based technology uses DNA supercoiling to convert nucleic acid hybridization into a mechanical signal for rapid diagnostics. The first application is for the detection of drug-resistant microbes, specifically tuberculosis.
- Jul 2025Grant (prize money)$3M
- Jun 2025Grant (prize money)$5M
- May 2025Grant (prize money)$3.3M
- Aug 2023Grant (prize money)$2M
#2
Series B · Baltimore, Maryland · founded 2014 · 6 employees$3.5Mraised▾
Foundation focused on detection and prevention of fungal infections
- Mar 2026Series B$11.2M
- Jun 2022Series A$3.5M
- Mar 2021Grant (prize money)$976.6K
- Jul 2015Grant (prize money)$175K
#3
Funding Raised · Baltimore, Maryland · founded 2015 · 8 employees$6.5Mraised▾
Developer of diagnostic assays for HIV. The assay detects ultra-rare analytes of HIV and other viral infections in the blood. The company uses ddPCR, qPCR, sequencing, and also culture-based methods to develop assays.
- Apr 2025Grant (prize money)$755.3K
- Feb 2025Grant (prize money)$600K
- Jul 2021Grant (prize money)$600K
- Dec 2019Grant (prize money)$300K
#4
Series A · Baltimore, Maryland · founded 2018$7.2Mraised▾
Developer of therapeutics for infectious diseases. It offers ZP5-9676 a single-dose therapy intended to treat soil-transmitted helminths, including Ascaris (roundworm), Trichuris (whipworm), Necator americanus and the uncommon Ancylostoma duodenale.
- Apr 2025Series A$4.3M
- Jul 2023Series A$7.2M
#5
Series C · Baltimore, Maryland · founded 2011 · 74 employees$75Mraised▾
Offers automated tools for operational planning and analytics for the e-waste industry. The company offers technology solutions for managing supply chain performance. It includes automated operational planning tools, grading systems, inventory solutions, life cycle management, and more.
- Jan 2023Series C$37.5M
- Feb 2022Series B$14.4M
- Oct 2020Series B$14M
- Oct 2020Conventional Debt—
#6
Funding Raised · Baltimore, Maryland · founded 1996 · 14 employees$597.3Kraised▾
ThermoChem Recovery International(TRI) develops technologies in the thermochemical conversion of a wide range of biomass and waste feedstocks. Their projects include MSW-to-jet and diesel fuels, woody biomass to drop-in fuels, lignite coal-to-diesel, MSW-to-combined cycle power generation etc.
- Apr 2025Grant (prize money)$543.3K
- Apr 2025Grant (prize money)$53.9K
#7
Seed · Baltimore, Maryland · founded 2020 · 8 employees$3.2Mraised▾
Manufacturer of blood test diagnostic device
- Apr 2024Seed$250K
- Jun 2023Seed$2M
- May 2023Grant (prize money)$294.6K
- Jan 2022Seed$850K
#8
Seed · Baltimore, Maryland · founded 2018 · 3 employees$500Kraised▾
Operator of a global health company intended to create accessible medtech products for patients. The company is focused on providing an accessible, accurate diagnosis for tuberculosis patients, helping patients to cure diseases at low-cost and high-performance diagnostics mainly for infectious diseases in communities.
- Nov 2024Seed$500K
#9
Seed · Baltimore, Maryland · founded 2022 · 3 employees$3Mraised▾
Electrochemical production company focused on decarbonization. It provides solutions for the development of negative-emission technologies and decarbonization through affordable, scalable direct air capture of carbon dioxide, carbon-negative mining, and other Ph swing applications.
- Aug 2023Seed$3M
#10
Deadpooled · Baltimore, Maryland · founded 2005 · 3 employees$18.9Mraised▾
Profectus BioSciences is a clinical stage vaccine company devoted to preventing and treating viral diseases through the application of its proprietary Prime/Boost System of Vaccines (PBS Vax) platform. PBS Vax provides the ability to “tune” the immune response to whatever is required for a specific target and disease context. The Company’s vaccine targets include HCV, HPV, HSV, HIV, Ebola/Marburg and malaria. Also developing oncolytic vesiculovirus vaccines for the treatment of advanced-stage cancers in partnership with Vyriad.
- May 2016Series A$300K
- Dec 2015Grant (prize money)$4.6M
- Oct 2014Grant (prize money)$9.5M
- Aug 2014Series A$7.5M
#11
Deadpooled · Baltimore, Maryland · founded 2014 · 3 employees$9.8Mraised▾
PathoVax is focused on the development of universal Human Papillomavirus (HPV) vaccine to provide prophylaxis against all HPV-related cancers and diseases. The company claims that its pilot vaccine, RGVax, promises to provide protection against all 15 oncogenic HPVs and many others that cause various warts.
- May 2020Grant (prize money)$1.4M
- Mar 2019Grant (prize money)$300K
- May 2018Seed$2.8M
- Jan 2018Grant (prize money)$225K
#12
Funding Raised · Baltimore, Maryland · founded 2012 · 39 employees$3Mraised▾
The Baltimore Regional Housing Partnership (BRHP), a nonprofit organization, is the Regional Administrator for the Baltimore Housing Mobility Program. The Baltimore Housing Mobility Program has opened pathways to a better future for low-income families for nearly 15 years. BRHP currently provides over 4,000 low-income families expanded housing, educational, and employment options in opportunity areas across the Baltimore region. Each family that chooses to participate and completes the counseling program receives a Housing Choice Voucher, high-quality housing and financial counseling, and support in the transition to the new neighborhood and schools.
- May 2022Grant (prize money)$3M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Sustainability Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Climate Adaptation is moving in the United States
A read on the academic research around Climate Adaptation — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,953 United States-affiliated papers.
- Columbia University52
- University of North Carolina at Chapel Hill43
- Arizona State University42
- Texas A&M University42
- Purdue University West Lafayette35
- Flood myth4→56
- Climate change6→47
- Flooding (psychology)2→23
- Climate resilience1→16
- Flood mitigation2→14
- Flood myth50→178
- Climate change35→155
- Flooding (psychology)18→97
- Resilience (materials science)10→84
- Psychological resilience12→55
- Climate change71→449
- Resilience (materials science)17→139
- Flood myth36→158
- Psychological resilience13→115
- Climate resilience14→92
Where climate adaptation is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing climate adaptation patents in the United States
United States climate adaptation patent filing is cooling — 28 filings from 19 assignees (2016–2025), led by ILC Dover, Garcia Rogerio, Serralta Denset; annual filings 6→1.
- ILC Dover20
- Garcia Rogerio4
- Serralta Denset4
- Zesty AI2
- Yodock GUY1
- Mckee TONY RAY1
- Ballard Tristan1
- Cooper Matthew1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.