Best Sustainability Tech Companies in Columbus, United States
The 33 best Sustainability Tech companies in Columbus, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Appalachian Power.
Our analysis of 84 Sustainability Tech companies
$19.4b in tracked funding; 85% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Sustainability Tech companies in Columbus
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Appalachian Power Provider of power consumption monitoring solutions | $600M | 67 mo ago | Funding Raised | — | 2001 | Google MapsEnvoystyled-components+13 | — | — |
| 2 | Clarametyx Developer of biologic therapies and vaccines for biofilm-related chronic bacterial infections | $33M | 21 mo ago | Series A | — | 2019 | — | — | — |
| 3 | Exacter Provider of asset intelligence data analytics solutions | $16M | 89 mo ago | Series B | John Lauletta CEO | 2005 | — | 15 patents Arc detection and analysis for power equipment monitoring and fault diagnostics | — |
| 4 | Invirsa Natural small molecule indicated for acute conjunctivitis of viral origin | $9M | 15 mo ago | Series B | — | 2014 | — | 42 patents Ophthalmic ADP‑ribose therapeutics for VEGF modulation and visual acuity improvement | — |
| 5 | MetaMateria Nanotechnology solutions for waste water treatment | $7M | 76 mo ago | Funding Raised | Richard Schorr Founder & CEO | 2002 | — | 6 patents Porous composite media for phosphorus removal from water and cement manufacturing. | — |
| 6 | Armatus Developer of precision gene therapies for rare diseases | $3M | 18 mo ago | Seed | Scott Harper Co-Founder | 2020 | WordPressMySQLPHP+19 | — | — |
| 7 | New Resource Solutions Online platform to connect investors with solar energy projects | $710K | 51 mo ago | Seed | Geoff Greenfield Co-Founder | 2016 | — | — | — |
| 8 | ProclaRx Developing bacterial film inhibitor drugs for infectious diseases | $512K | 116 mo ago | Funding Raised | — | 2014 | — | — | — |
| 9 | PlugOp Provider of energy management solution | $120K | 16 mo ago | Seed | Tyler Simons Co-Founder | 2022 | RubyChart.jsUbuntu+9 | — | — |
| 10 | Vertiv Provider of power, thermal, and IT infrastructure solutions and services | — | 48 mo ago | Public | Giordano Albertazzi CEO | 1946 | Apple iCloud MailMicrosoft 365Vimeo+33 | 765 patents Data center power distribution and liquid cooling infrastructure for high‑density IT equipment. | — |
Top 10 Sustainability Tech companies in Columbus
#1
Series B · Columbus, Ohio · founded 2014 · 3 employees$9.3Mraised▾
Natural small molecule indicated for acute conjunctivitis of viral origin. The lead candidate, INV-102, is derived from a naturally occurring small molecule that modulates the activity of three parallel enzyme systems that are critical to innate immune response. NV-102 significantly reduces plaque formation caused by adenovirus. The candidate shows a strong anti-inflammatory response in acute conjunctivitis, without the side effects from other therapeutics like steroids.
- Jul 2025Series B$2.9M
- Nov 2023Series B$1000K
- Jun 2023Series B$7.7M
- Dec 2020Seed$40.2K
#2
Series A · Columbus, Ohio · founded 2019 · 14 employees$33Mraised▾
Clarametyx Biosciences has developed biologic therapies and vaccines for biofilm-related bacterial infections affecting the respiratory tracts. The company has developed its lead product CMTX-001, an immune-enabling antibody therapy, to treat hospital-acquired pneumonia (preclinical development stage). It is also developing therapies for cystic fibrosis, sinusitis, and post-tympanostomy tube otorrhea.
- Jan 2025Series A—
- Jan 2024Series A$33M
- Apr 2022Grant (prize money)$3.9M
- Jan 2022Grant (prize money)$3.1M
#3
Seed · Columbus, Ohio · founded 2020 · 9 employees$3Mraised▾
Developer of precision gene therapies for rare diseases. It offers AAV-based gene replacement therapy candidates which include ARM 101, ARM 102, ARM 201, and ARM 202 for neuromuscular disorders.
- May 2025Seed$3M
#4
Seed · Columbus, Ohio · founded 2022$120Kraised▾
Provider of energy management solution. It offers optimization based energy management that allows property managers to provide a premium charging experience at a fraction of the cost. It also provides smart load management software that allows multiple chargers to be configured on a single circuit, drastically reducing electrical infrastructure upgrade requirements.
- Jun 2025Seed$70K
- Dec 2024Seed$100K
- Mar 2024Seed$20K
- Dec 2023Conventional Debt—
#5
Funding Raised · Columbus, Ohio · founded 2001 · 3200 employees$600.2Mraised▾
Appalachian Power provides power consumption monitoring solutions. It provides a mobile application for users to pay bills and report outages. It also allows users to view real-time account balance, payment due date, balance details, etc. and schedule bill payments. Also, provides updates on power outages, alert notifications, etc.
- Mar 2021Conventional Debt$100M
- 2020Conventional Debt$500M
- Sep 2010Grant (prize money)$195.1K
#6
Series B · Columbus, Ohio · founded 2005 · 12 employees$16Mraised▾
Provider of asset intelligence data analytics solutions. It offers visibility of the grid into grid health, identifying areas of safety and system risk, and informing asset management & intelligence-based reliability initiatives. Also offers an information tool for managing multiple aspects of overhead distribution reliability and asset management.
- May 2019Grant (prize money)—
- Jan 2015Series A$3M
- Mar 2007Seed$5M
- Series B$8M
#7
Funding Raised · Columbus, Ohio · founded 2002$7Mraised▾
Nanotechnology solutions for wastewater treatment. It offers the company has developed a porous ceramic product Bio-Lair which can be suspended in the wastewater. The product using bacteria results in nutrient recycling of water. The technology finds application in diverse sets of industries.
- Jun 2020Grant (prize money)$206.5K
- Jul 2018Grant (prize money)$150K
- Jun 2015Grant (prize money)$1.1M
- Apr 2013Grant (prize money)$600K
#8
Seed · Columbus, Ohio · founded 2016$710Kraised▾
New Resource Solutions is an online platform to connect investors with solar energy projects. Enables project developers and investors to connect with each other through the platform and get the financing for the project. Caters to multiple industries including solar energy, wind energy, and others.
- Aug 2022Seed$310K
- Mar 2017Conventional Debt$400K
#9
Funding Raised · Columbus, Ohio · founded 2014 · 3 employees$512Kraised▾
ProclaRx (formerly known as Lattice Biotech), a spinoff from research at Nationwide Children’s Hospital is focussed on developing therapeutics for bacterial infections. Its technology includes an antibody that binds to the proteins in the bacterial biofilm. It is developing anti-infectives both as combination devices and as biologics with multiple candidates in development. Its lead candidates include PCL-1404 (in combination with a device) for advanced wound care and CVID sinusitis and PCL-1402, a biologic for Secretory Otitis Media. It also has other programs in prophylaxis, vaccine research and animal health.
- Feb 2017Conventional Debt$512K
#10
Public · Columbus, Ohio · founded 1946 · 27000 employees—raised▾
Provider of power, thermal, and IT infrastructure solutions and services. The company delivers technologies and customized solutions to meet specific business requirements. Its portfolio includes uninterruptible power supplies, power distribution, and thermal management. The company also offers racks, enclosures, monitoring, and digital infrastructure management.
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Sustainability Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Climate Adaptation is moving in the United States
A read on the academic research around Climate Adaptation — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,953 United States-affiliated papers.
- Columbia University52
- University of North Carolina at Chapel Hill43
- Arizona State University42
- Texas A&M University42
- Purdue University West Lafayette35
- Flood myth4→56
- Climate change6→47
- Flooding (psychology)2→23
- Climate resilience1→16
- Flood mitigation2→14
- Flood myth50→178
- Climate change35→155
- Flooding (psychology)18→97
- Resilience (materials science)10→84
- Psychological resilience12→55
- Climate change71→449
- Resilience (materials science)17→139
- Flood myth36→158
- Psychological resilience13→115
- Climate resilience14→92
Where climate adaptation is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing climate adaptation patents in the United States
United States climate adaptation patent filing is cooling — 28 filings from 19 assignees (2016–2025), led by ILC Dover, Garcia Rogerio, Serralta Denset; annual filings 6→1.
- ILC Dover20
- Garcia Rogerio4
- Serralta Denset4
- Zesty AI2
- Yodock GUY1
- Mckee TONY RAY1
- Ballard Tristan1
- Cooper Matthew1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.