Best Sustainability Tech Companies in Missouri, United States
The 76 best Sustainability Tech companies in Missouri, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Aclara Technologies.
Our analysis of 84 Sustainability Tech companies
$19.4b in tracked funding; 85% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Sustainability Tech companies in Missouri
| # | Company | Disclosed funding | Employees | Stage | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Aclara Technologies Connective platform for smart grid | $450M | 1,700 | Acquired | 1972 | — | 26 patents Smart grid communication, metrology, and security technologies for power distribution networks | — |
| 2 | LPOXY Therapeutics Developer of therapies for infectious disease prevention 24Funding top 42%Talent bottom 49%Global bottom 25%News bottom 18% All 4 signals ▾Fundingtop 42% Talentbottom 49% Globalbottom 25% Newsbottom 18% Funding: Raised $28.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 24/100 | $28M | — | Series A | 2020 | — | — | — |
| 3 | Site 1001 Mobile-first cloud based software for facility management tasks | $17M | 70 | Deadpooled | 2016 | — | — | — |
| 4 | QM Power Provider of energy efficient motor | $16M | 23 | Series C | 2006 | — | 256 patents Liquid‑cooled high‑efficiency power supplies and converters for IT equipment | — |
| 5 | Fimbrion Therapeutics Pioneering anti-virulence therapeutics for urinary tract infections and tuberculosis | $10M | 6 | Funding Raised | 2012 | — | — | — |
| 6 | BacterioScan Bacterial screening device for diagnosis and treatment of infectious diseases | $8M | 14 | Series A | 2004 | — | 14 patents Rapid optical detection and antibiotic susceptibility testing of microbes in fluid samples | — |
| 7 | IHA Operator of housing programs providing assistance and resources to residents | $7M | — | Funding Raised | 2020 | DNNGoogle MapsBootstrap+13 | — | — |
| 8 | Renew Biomass Provider of solution biomass | $7M | 13 | Series A | 2015 | — | — | — |
| 9 | Omniose Developer of polysaccharide conjugate vaccines against bacterial threats | $4M | 7 | Seed | 2016 | — | — | — |
| 10 | Verde Resources Provider of sustainable materials and solutions for reducing carbon footprint | $2M | 38 | Public | 2010 | WordPressMySQLPHP+16 | — | — |
| 11 | Dynamhex Provider of air quality monitoring and visualization solutions | $2M | 11 | Seed | 2018 | — | — | — |
| 12 | Zego Online solution to manage residential communities | $2M | 20 | Acqui-Hired | 2017 | — | — | — |
| 13 | MagBiosense POC device for cardiac disease diagnosis | $1M | 3 | Funding Raised | 2011 | — | 2 patents Low‑autofluorescence capture surfaces for fluorescence‑based bioassays | — |
| 14 | NanoporeDX Developer of rapid and portable microbial diagnostics | $635K | 6 | Deadpooled | 2012 | — | — | — |
| 15 | Precision Virologics Developing biologically targeted adenovirus vaccines to treat infectious diseases | $500K | 2 | Deadpooled | 2016 | — | — | — |
| 16 | Cicadea Biotech Developer of PCR-based assays | $305K | — | Funding Raised | 2018 | — | — | — |
| 17 | Keybot Provides solution for visitor management | $120K | — | Deadpooled | 2016 | — | — | — |
| 18 | NEER Offering solutions for water infrastructure modeling and asset management | $100K | 9 | Seed | 2020 | Webflow EcommerceWebflowjQuery+10 | — | 4 launchs |
Top 12 Sustainability Tech companies in Missouri
#1
Funding Raised · Independence, Missouri · founded 2020$7Mraised▾
Operator of housing programs providing assistance and resources to residents. It administers public housing and Section 8 programs, offering accommodations and subsidies to eligible individuals and families. The organization provides access to information, forms, and portals for residents, landlords, and employees. It also maintains and publishes documents such as annual plans, financial reports, and meeting minutes.
- Nov 2025Grant (prize money)$45.1K
- Sep 2025Grant (prize money)$2M
- Sep 2025Grant (prize money)$221.2K
- May 2025Grant (prize money)$1.5M
#2
Series A · Platte City, Missouri · founded 2020$28Mraised▾
Developer of therapies for infectious disease prevention. It offers an oral therapeutic, Sidiprev, which aims to prevent Clostridioides difficile infection by delivering oxygen directly to the bowel.
- Sep 2025Series A$28M
#3
Funding Raised · St. Louis, Missouri · founded 2012 · 6 employees$10.3Mraised▾
Pioneering anti-virulence therapeutics for urinary tract infections and tuberculosis. The company focuses on developing novel antibacterial therapies and alternatives to traditional antibiotics. They are dedicated to creating powerful solutions to combat infectious diseases, particularly urinary tract infections and tuberculosis. Their pipeline includes oral antibacterial co-development and antibiotic-sparing approaches. They are committed to pioneering anti-virulence solutions, researching and developing innovative treatments. The company's work has potential social impact by addressing antibiotic resistance. They are involved in drug discovery and development, aiming to provide effective treatments for infectious diseases.
- Jul 2025Grant (prize money)$300K
- May 2025Grant (prize money)$600K
- Feb 2025Grant (prize money)$3M
- Mar 2023Grant (prize money)$600K
#4
Public · St. Louis, Missouri · founded 2010 · 38 employees$2Mraised▾
Provider of sustainable materials and solutions for reducing carbon footprint. It specializes in sustainable infrastructure solutions, focusing on net zero building materials and road construction products. Its flagship product, BioAsphalt, demonstrates the potential for carbon sequestration in infrastructure development. Itoperates through a proprietary technology that integrates biochar to reduce the carbon footprint of its products. The company aims to become a global leader in green-tech by transforming waste into renewable and sustainable products.
- Nov 2025Post IPO$2M
#5
Funding Raised · St. Louis, Missouri · founded 2018$305Kraised▾
Cicadea Biotech is a developer of PCR-based assays. The company has developed pathogen detection RT-PCR kits with customized assays to detect specific DNA fragments of pathogenic microbes in food, animal feed, water, environmental and industrial products. It also provides services like custom PCR assays, high throughput PCR testing, digital PCR assays to detect cancer mutation, and high throughput DNA extraction.
- Apr 2025Grant (prize money)$305K
#6
Acquired · Hazelwood, Missouri · founded 1972 · 1700 employees$450Mraised▾
Aclara Technologies(owned by an affiliate of Sun Capital Partners) is a supplier of smart infrastructure solutions (SIS) to water, gas, and electric utilities globally SIS magnifies the benefits of networks that perform automated metering reading by incorporating a range of sensors, communications, and analytic technologies that let utilities monitor their distribution networks, optimize operations, respond to issues quickly, and preempt problems. Aclara’s Synergize RF electric network offers two-way communications and provides a connective platform for the smart grid. It acquired GE Energy Management’s grid solutions electricity meter business from General Electric Company.
- Jun 2017Conventional Debt$105M
- Aug 2016Conventional Debt$345M
#7
Seed · St. Louis, Missouri · founded 2016 · 7 employees$3.6Mraised▾
Developer of polysaccharide conjugate vaccines against bacterial threats. The company utilizes a proprietary bioconjugation platform to develop novel polysaccharide-protein conjugate vaccines targeting infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis.
- Sep 2023Grant (prize money)—
- Oct 2022Grant (prize money)$3.6M
- Jun 2021Seed—
- 2017Grant (prize money)$50K
#8
Series C · Kansas City, Missouri · founded 2006 · 23 employees$16.1Mraised▾
Provider of energy efficient motor. It provides energy-efficient electric motors and software to manage electric motors. They concentrate on creating cutting-edge technology to increase efficiency and are a quickly expanding business with cutting-edge research and development labs.
- Mar 2018Series C$1M
- Mar 2016Series C$9.1M
- Nov 2015Conventional Debt$2M
- 2014Grant (prize money)$1M
#9
Deadpooled · Kansas City, Missouri · founded 2016 · 70 employees$17.3Mraised▾
Site 1001 is a cloud-based mobile-first software platform for the facilities maintenance and building management industry. The company digitizes and automates facility management tasks on the cloud. It offers building automation and Internet of things (IoT) solution to provide building intelligence for facility professionals, building owners, managers, and operators. Some of the features the location smart software offers are preventative maintenance schedules; vendor/sub management tools; budget, labor, and usage reports; BIM/CAD, IoT, and third party systems integrations; and inventory management tools.
- Sep 2018Series A$6.3M
- Jul 2017Series A$6M
- Oct 2016Series A$5M
#10
Series A · St. Louis, Missouri · founded 2004 · 14 employees$7.7Mraised▾
Bacterial screening device for diagnosis and treatment of infectious diseases. The instrumentation detects and measures microorganism growth in liquid specimens, determines if it is resistant to a range of antibiotics, and provides clinicians with patient-specific guidance. The real-time bacteria detection and antimicrobial resistance data it collects through its network can be used for clinical decision-making.
- Dec 2017Grant (prize money)$209.3K
- Aug 2015Series A$1.7M
- Feb 2015Series A$6M
- Dec 2014Series A—
#11
Series A · Springfield, Missouri · founded 2015 · 13 employees$6.9Mraised▾
Provider of solution biomass
- Mar 2015Series A$6.9M
#12
Seed · Kansas City, Missouri · founded 2018 · 11 employees$1.5Mraised▾
Dynamhex provides air quality monitoring and visualization solutions. It provides solutions for emission reductions. It gamified climate change mitigation actions. It also provides solutions to monitor and visualize the energy consumption. It provides solutions for both individuals and organizations.
- Mar 2021Seed$1.5M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Sustainability Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Climate Adaptation is moving in the United States
A read on the academic research around Climate Adaptation — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,953 United States-affiliated papers.
- Columbia University52
- University of North Carolina at Chapel Hill43
- Arizona State University42
- Texas A&M University42
- Purdue University West Lafayette35
- Flood myth4→56
- Climate change6→47
- Flooding (psychology)2→23
- Climate resilience1→16
- Flood mitigation2→14
- Flood myth50→178
- Climate change35→155
- Flooding (psychology)18→97
- Resilience (materials science)10→84
- Psychological resilience12→55
- Climate change71→449
- Resilience (materials science)17→139
- Flood myth36→158
- Psychological resilience13→115
- Climate resilience14→92
Where climate adaptation is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing climate adaptation patents in the United States
United States climate adaptation patent filing is cooling — 28 filings from 19 assignees (2016–2025), led by ILC Dover, Garcia Rogerio, Serralta Denset; annual filings 6→1.
- ILC Dover20
- Garcia Rogerio4
- Serralta Denset4
- Zesty AI2
- Yodock GUY1
- Mckee TONY RAY1
- Ballard Tristan1
- Cooper Matthew1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.