Best Sustainability Tech Companies in Palo Alto, United States
The 45 best Sustainability Tech companies in Palo Alto, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: AiDASH.
Our analysis of 84 Sustainability Tech companies
$19.4b in tracked funding; 85% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Sustainability Tech companies in Palo Alto
| # | Company | Disclosed funding | Last round | Stage | Employees | Founded | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | AiDASH AI-powered platform for managing critical infrastructure assets | $143M | 29 mo ago | Series C | 251 251 → 392 (+56%) | 2019 | Abhishek Singh Co-Founder & CEO | 40 patents Geospatial image analysis and environmental monitoring for infrastructure and habitat assessment | — |
| 2 | Anacor Pharmaceuticals Developer of small-molecule therapeutics for the treatment of infectious and autoimmune diseases | $90M | 124 mo ago | Acquired | 110 | 2002 | — | 767 patents Oxaborole-based topical anti-inflammatory and antiparasitic pharmaceutical compounds | — |
| 3 | Ancora Biotech Developer of Immunotherapeutics for B cell cancers, metabolic diseases, and chronic hepatitis B infections | $60M | 50 mo ago | Series A | 12 | 2021 | Ben Buelow CEO | — | — |
| 4 | Overture Life Developer of embryology diagnosis device for professionals 67Patents top 26%AI top 28%Talent top 28%Funding top 29% All 11 signals ▾Patentstop 26% AItop 28% Talenttop 28% Fundingtop 29% Moattop 31% Innovationtop 32% Growthtop 35% Techbottom 44% Globalbottom 43% Marketbottom 37% Newsbottom 18% Patents: 44 patents matched (strict assignee match) · 34 filings since 2022 vs 10 in 2017-21 AI: Holds AI/ML patents (G06N-family CPC) · Product described with: ai powered rank vs industry peers · Fliar Intelligence Index 67/100 | $37M | 9 mo ago | Series C | 41 | 2017 | Jose Horcajadas Co-Founder & Chief Scientific Officer | 44 patents Automated microinjection and microfluidic IVF/embryo handling technologies | 1 launch · 1 partnership |
| 5 | Topica Pharma Topical antifungal treatments | $32M | 158 mo ago | Series B | 11 | 2008 | — | — | — |
| 6 | Noon Provider of solutions for flow batteries | $31M | 33 mo ago | Series A | 7 | 2018 | Christopher Graves Founder & CEO | — | 1 partnership |
| 7 | WindBorne Systems AI-powered models and a global network of long-duration smart balloons | $23M | 27 mo ago | Series A | 11 | 2019 | Kai Marshland Co-Founder & Chief Product Officer | — | — |
| 8 | Surf Bio Developer of therapeutics for the treatment of multiple diseases | $16M | 27 mo ago | Acquired | 4 | 2021 | Jennifer Schneider Md Founder | — | — |
| 9 | Qvin Provider of software solutions and Q- pad for women's health monitoring & tracking | $12M | 69 mo ago | Series A | 24 | 2014 | Sara Naseri Co-Founder | 3 patents Automated closure mechanisms for containers and packaging lids | — |
| 10 | Plutoshift AI-powered performance monitoring platform for industrial water assets and processes | $11M | 25 mo ago | Series A | 18 | 2016 | — | — | — |
| 11 | ID-FISH Technology Innovative diagnostic solutions for infectious diseases using FISH and ImmunoBlot technologies | $10M | 150 mo ago | Funding Raised | — | 2000 | Jyotsna Shah Co-Founder & CSO | 46 patents Molecular diagnostic assays for vector-borne pathogens (ticks, malaria, Bartonella, Babesia). | — |
| 12 | Arixa Pharmaceuticals Developer of prodrug for resistant gram-negative infections | $8M | 99 mo ago | Seed | — | 2016 | Eric Gordon Co-Founder & CSO | — | — |
| 13 | Rune Energy Computation technology for power plants | $6M | 25 mo ago | Series A | — | 2023 | Varun Palivela Co-Founder | — | — |
| 14 | NanoSpun Technologies Provider of biological nanotechnology solutions for municipal and industrial wastewater treatment | $5M | 158 mo ago | Series A | 3 | 2011 | — | — | — |
| 15 | Circularity Fuels Developer of renewable hydrocarbon fuels from captured carbon | $5M | 18 mo ago | Funding Raised | — | 2023 | Stephen Beaton Co-Founder & CEO | 5 patents Capturing CO₂ and converting it to high-purity methane at atmospheric pressure. | — |
| 16 | Domatic Provider of low-voltage smart building solutions. It offers a simplified system for wiring and networking… | $4M | 16 mo ago | Series A | 9 | 2019 | Jim Baldwin Co-Founder & CEO | 3 patents Secure IoT device tunneling and smart low‑voltage power delivery systems | — |
| 17 | Rock Rabbit Provider of AI-based software solutions for construction management | $3M | 21 mo ago | Series A | — | 2023 | Aimee Bailey Co-Founder & CEO | — | — |
| 18 | DACLAB A climate technology company that develops and commercializes direct air capture (DAC) solutions to empower… | $3M | 11 mo ago | Seed | — | 2023 | Aditya Bhandari Co-Founder & CEO | — | — |
| 19 | Carmenta Bio Diagnostics for women's health | $3M | 156 mo ago | Acqui-Hired | 4 | 2012 | Bruce Ling Co-founder | — | — |
| 20 | SunToWater Technologies Water generation by dehumidifying the air | $2M | 83 mo ago | Seed | 8 | 2012 | Benjamin Blumenthal Co-Founder | — | — |
| 21 | The Detection Group Wireless water leak detection system provider | $2M | 121 mo ago | Acquired | 24 | 2006 | Tom Barth Chief Executive Officer | 14 patents Wireless water leak detection and localization using sensor cables and wireless communication | — |
| 22 | Spiio Provider of sensors to monitor moisture content in the soil | $2M | 66 mo ago | Seed | 5 | 2015 | Chris Thorup Co-Founder | — | — |
| 23 | Isentio Rapid pathogen identification using DNA sequencing with user-friendly SaaS solution | $2M | 187 mo ago | Acqui-Hired | 7 | 2005 | Oyvind Kommedal Co-Founder | — | — |
Top 12 Sustainability Tech companies in Palo Alto
#1
Series C · Palo Alto, California · founded 2017 · 41 employees$37Mraised▾
Developer of embryology diagnosis device for professionals. It offers DaVitri an automated platform designed to modernize egg freezing and embryo warming workflows, automates critical timing and cryoprotectant exposure steps for improved consistency and oocyte survival rates. It also offers m|z test an AI powered metabolomic test designed for non-invasive embryo selection.
- Nov 2025Conventional Debt$23M
- Apr 2025Series C$20.6M
- May 2021Series B$15M
- Dec 2018Series A$13.6M
#2
Seed · Palo Alto, California · founded 2023$3Mraised▾
A climate technology company that develops and commercializes direct air capture (DAC) solutions to empower carbon capture. The solution helps build sustainable future and achieve carbon neutrality.
- Sep 2025Seed$3M
#3
Series A · Palo Alto, California · founded 2019 · 9 employees$4.1Mraised▾
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- Apr 2025Series A$100K
- Oct 2022Series A$4M
- Jan 2021Seed$150K
- Jan 2020Seed—
#4
Series C · Palo Alto, California · founded 2019 · 251 employees$143Mraised▾
AI-powered platform for managing critical infrastructure assets. It offers intelligent vegetation management, wildfire mitigation planning, and climate risk intelligence. It also provides asset inspection, monitoring, and biodiversity net gain management. It supports electric, gas, water, wastewater, energy, mining, and transportation industries.
- Mar 2024Series C$58.5M
- Jan 2024Series C$50M
- Nov 2022Series B$10M
- Oct 2021Series B$27M
#5
Funding Raised · Palo Alto, California · founded 2023$5.2Mraised▾
Developer of renewable hydrocarbon fuels from captured carbon. This company converts renewable energy into hydrocarbon fuels using a patent-pending process. The process is significantly more cost-effective than existing methods for producing electrofuels. The resulting fuels are compatible with current global industrial applications, offering a sustainable alternative to fossil fuels. The technology utilizes carbon already present in the atmosphere or other dilute streams, eliminating the need for traditional fossil fuel extraction.
- Feb 2025Grant (prize money)$4.9M
- Sep 2024Grant (prize money)$275K
#6
Series A · Palo Alto, California · founded 2023$3.1Mraised▾
Provider of AI-based software solutions for construction management. It provides users with an AI-powered platform that streamlines the rebate process for contractors and homeowners, allowing them to focus on their projects.
- Nov 2024Series A$6M
- Feb 2024Seed$3.1M
#7
Series A · Palo Alto, California · founded 2019 · 11 employees$23.4Mraised▾
AI-powered models and a global network of long-duration smart balloons. It designs and operates technology to capture atmospheric profiles. The company provides access to data, including over oceans and remote places. It offers a deep learning forecast model utilizing proprietary data. The company transforms forecast data into actionable insights and automations.
- May 2024Series A$15M
- May 2023Seed$9.9M
- 2019Seed—
#8
Series A · Palo Alto, California · founded 2016 · 18 employees$10.8Mraised▾
Plutoshift provides an artificial intelligence-powered performance monitoring platform for industrial water assets and processes. Enables industries to prevent water wastage, predict asset failures and minimize operating costs. Claims to use proprietary data science algorithms to analyze & visualize the data from industrial data silos and SCADA systems. The data can be monitored through dashboards & users can assess asset performance data with impact on financial metrics. The software is offered as a SaaS model.
- Jul 2024Series A$400K
- Mar 2024Series A$250K
- May 2020Series A—
- Sep 2019Series A$8M
#9
Series A · Palo Alto, California · founded 2018 · 7 employees$31Mraised▾
Provider of solutions for flow batteries. Its battery solutions allow users to store renewable energy from solar and wind energy sources at a low cost.
- Nov 2023Grant (prize money)—
- Dec 2022Series A$28M
- Dec 2020Seed$3M
- Apr 2020Grant (prize money)$500K
#10
Acquired · Palo Alto, California · founded 2021 · 4 employees$16Mraised▾
Developer of therapeutics for the treatment of multiple diseases. The company leverages a novel biotechnology platform to develop therapeutic solutions for diabetes, oncology, infectious diseases, gene therapy, and other therapeutic areas. The company's flagship program is novel, ultra-rapid insulin for the treatment of diabetes.
- Apr 2024Grant (prize money)$1.6M
- Apr 2022Seed$16M
#11
Series A · Palo Alto, California · founded 2023$5.6Mraised▾
Computation technology for power plants. It uses a Clipping and Curtailment Conversion System(CC/CS) for the management of power plants. It offers control systems to measure, and consume only the wasted portion of energy, monitoring systems for the power plant controller, supervisor control for manual override of data-center power consumption, APIs for compatibility with existing SCADA systems, and more.
- Jul 2024Series A$5.6M
#12
Series A · Palo Alto, California · founded 2021 · 12 employees$60Mraised▾
Developer of Immunotherapeutics for B cell cancers, metabolic diseases, and chronic hepatitis B infections. It offers multi-specific antibodies which include TNB-486 T cell engager for the treatment of B cell cancers, TNB-738 enzyme inhibitor for the treatment of inflammatory and metabolic disorders, and anti-HBVxCD3 for the curative treatment of chronic hepatitis B infections.
- Jun 2022Series A$60M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Sustainability Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Climate Adaptation is moving in the United States
A read on the academic research around Climate Adaptation — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,953 United States-affiliated papers.
- Columbia University52
- University of North Carolina at Chapel Hill43
- Arizona State University42
- Texas A&M University42
- Purdue University West Lafayette35
- Flood myth4→56
- Climate change6→47
- Flooding (psychology)2→23
- Climate resilience1→16
- Flood mitigation2→14
- Flood myth50→178
- Climate change35→155
- Flooding (psychology)18→97
- Resilience (materials science)10→84
- Psychological resilience12→55
- Climate change71→449
- Resilience (materials science)17→139
- Flood myth36→158
- Psychological resilience13→115
- Climate resilience14→92
Where climate adaptation is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing climate adaptation patents in the United States
United States climate adaptation patent filing is cooling — 28 filings from 19 assignees (2016–2025), led by ILC Dover, Garcia Rogerio, Serralta Denset; annual filings 6→1.
- ILC Dover20
- Garcia Rogerio4
- Serralta Denset4
- Zesty AI2
- Yodock GUY1
- Mckee TONY RAY1
- Ballard Tristan1
- Cooper Matthew1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.