Best Sustainability Tech Companies in Philadelphia, United States
The 49 best Sustainability Tech companies in Philadelphia, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Tarsa Therapeutics.
Our analysis of 84 Sustainability Tech companies
$19.4b in tracked funding; 85% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Sustainability Tech companies in Philadelphia
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | CustomChill Provider of custom chillers and thermoelectric chillers | — | — | Unfunded | — | Solomon Reznik CEO | WordPressMySQLPHP+16 | — | — |
| 2 | Customized Energy Solutions Demand response solutions | — | — | Unfunded | — | — | WordPressApple iCloud MailMySQL+24 | — | — |
| 3 | Delta Thermo Energy Developer of solid waste to biofuel conversion technology | — | — | Unfunded | — | Rob Van Naarden CEO | — | — | — |
| 4 | diamond and associates Diamond and Associates is a real estate development consultant in affordable housing, tax credits, community… | — | — | Private | 20 | — | — | — | 2 awards |
| 5 | dIoT Thermo Provider of solutions for energy monitoring and building automation | — | — | Deadpooled | — | Marco Bonifaccino Founder & CEO | — | — | — |
| 6 | Energy Management Systems Energy and efficiency solutions for commercial and residential real estate | — | — | Unfunded | — | Gregg Voltz CEO | WordPressMySQLPHP+28 | — | — |
| 7 | Graboyes Efficiency Tenant Provider of energy efficiency financing solutions and project management services | — | — | Unfunded | — | Sam Klein CEO & President | — | — | — |
| 8 | Green IT Provider of renewable energy asset management software solutions | — | — | Acquired | 21 | Andrew Eisenberg CEO | — | — | — |
Top 12 Sustainability Tech companies in Philadelphia
#1
Series A · Philadelphia, Pennsylvania · founded 2022$54Mraised▾
Developer of gene therapy medicines for neurological diseases. The company leverages precision delivery through Adeno-Associated Virus to target specific cells and tissues, to improve the lives of patients suffering from various central nervous system disorders.
- May 2026Series A$97M
- May 2024Series A$54M
#2
Series A · Philadelphia, Pennsylvania · founded 2015 · 48 employees$70.7Mraised▾
Excision BioTherapeutics, Inc., is a biotechnology company developing CRISPR-based therapies to cure viral infectious diseases. Excision is focused on improving the lives of chronically ill patients by eliminating viral genomes from infected individuals. By using CRISPR in unique ways, the Company has already demonstrated the first functional cure for HIV in animals. Excision is developing technologies and IP developed at Temple University and U.C. Berkeley. Excision is located in San Francisco, California and is supported by ARTIS Ventures, GreatPoint Ventures, Norwest Venture Partners, Adjuvant Capital, Cota Capital, WRVI Capital, IndusAge Partners, Loreda Holdings, Olive Tree, Anzu Partners, SilverRidge Venture Partners, Oakhouse Ventures, and Gaingels.
- Feb 2021Series A$60.7M
- Jun 2019Grant (prize money)$217.5K
- Sep 2017Seed$10M
#3
Series B · Philadelphia, Pennsylvania · founded 2009 · 2 employees$78.7Mraised▾
Developer of oral treatment for postmenopausal osteoporosis. The company has developed TBRIA (calcitonin-salmon delayed-release tablets), an oral formulation of calcitonin for the treatment of postmenopausal osteoporosis, and is seeking FDA approval. TBRIA contains salmon calcitonin, a peptide that is manufactured using recombinant DNA technology.
- Jul 2017Series B$549.9K
- Jan 2017Series B$1.6M
- Jul 2016Conventional Debt$1.2M
- Feb 2016Conventional Debt$2M
#4
Acqui-Hired · Philadelphia, Pennsylvania · founded 2008 · 27 employees$76.5Mraised▾
Viridity Energy is a Demand Side Management platform which regulates and controls the Demand Side/Consumer side of the Power market. Through its online software, VPower, it assists C&I power consumers optimize their power costs by accessing the power pool of the wholesale power market. To counter the losses that might occur due to mandatory DR programs, the users are offered Energy Intelligence through the platform to buy power from the wholesale market at a lower cost than Utilities, thus helping them reduce their energy costs. Apart from this they also assist renewable energy storage developers and generators in combinong renewable energy with storage and produce dispatchable electricity that the electric grid can rely upon. By combining solar with storage, the customer has a new opportunity to generate revenue through the wholesale markets and access tax credits designed to increase storage penetration.
- May 2016Series D$8.5M
- Apr 2015Series C—
- Aug 2012Series C$15M
- Jan 2011Series B$14M
#5
Series A · Philadelphia, Pennsylvania · founded 2018 · 28 employees$21.5Mraised▾
Provider of AI-driven energy management system. The system is a combination of smart outlets and smart power strips which run on a cloud-based machine learning platform. The software tools provide building power usage stats, with disaggregation based on devices, and automatically eliminates sources of energy wastage. The hardware products include a cloud-based smart outlet and power strip, which can be controlled via a web application.
- Apr 2021Series A$20M
- May 2020Seed$300K
- Jan 2019Seed$1.1M
- May 2018Seed$100K
#6
Acquired · Philadelphia, Pennsylvania · founded 1999 · 484 employees$43Mraised▾
Developer of therapeutics and drug-device combinations for urology and sexual health. The company had therapies for hypogonadism (Testim), testosterone replacement (Testopel, Striant) and erectile dysfunction (Edex, Osbon ErecAid, Stendra). In addition, it had also been developing therapies for respiratory diseases and rare disorders.
- Nov 2003Series D$43M
#7
Series A · Philadelphia, Pennsylvania · founded 2009 · 44 employees$4.8Mraised▾
Provider of a non-invasive breast cancer scanning device. The product, NoTouch BreastScan includes a computerized digital infrared imaging system for breast cancer detection. Other devices include cervAIcal an AI-enabled mobile colposcope for cervical cancer screening. Also, provides a Selfi platform for home breast health monitoring.
- Nov 2021Series A$480.3K
- Oct 2016Series A$1.2M
- 2016Series A—
- Sep 2015Series A$3M
#8
Deadpooled · Philadelphia, Pennsylvania · founded 2007$8.3Mraised▾
Molecular diagnostics company focused on rapid, accurate infectious disease detection, developing and commercializing sample-to-answer molecular diagnostic tests. They leverage proprietary technologies to increase the speed, accuracy, ease of use, and efficiency of infectious disease diagnosis. Their Detect-Ready assays target the rapid detection of infectious diseases, including MRSA, C. difficile, STDs, and foodborne pathogens. The company's real-time PCR tests are designed for increased accuracy and faster results, simplifying assay storage and use. Their patent-pending technologies provide a differential diagnosis engine to identify specific pathogens and differentiate them from other infectious sources, covering methods for detecting antibiotic-resistant strains. This innovative approach aims to provide cost-effective solutions for healthcare settings.
- 2013Series B—
- Apr 2012Series B$1.9M
- Mar 2012Series B$1.5M
- Jun 2010Series A$1.4M
#9
Series A · Philadelphia, Pennsylvania · founded 2013 · 202 employees$6.2Mraised▾
Developer of a smartphone-based DNA detection platform. The platform transforms mobile labs for advanced DNA diagnostics and real-time disease surveillance. The system includes a docking station for real-time qPCR, a mobile app to control the system and analyze results, and targeted test kits for preparing samples and identifying pathogens or diseases by their specific DNA or RNA signatures. The first application is a panel for diagnosing sexually transmitted diseases.
- May 2017Series A$4.5M
- Sep 2016Grant (prize money)$56.1K
- Jun 2016Grant (prize money)$55.9K
- Feb 2014Seed$400K
#10
Seed · Philadelphia, Pennsylvania · founded 2020$270Kraised▾
Provider of waste diversion operations automation and data management solutions. It provides operations automation and data management solutions for buildings and construction projects, focusing on modern bulk pickup for multi-family residences.
- Mar 2024Seed$150K
- Oct 2022Seed$100K
- 2022Seed$20K
#11
Seed · Philadelphia, Pennsylvania · founded 2015 · 6 employees$4.2Mraised▾
LIA Diagnostics develops paper pregnancy tests that are foldable and disposable. This addresses the challenges surrounding privacy, usability, and sustainability in current at-home diagnostics.It claims that the product is scheduled to go on sale in 2016-17. LIA Diagnostics won the Innovative Idea Competition award at Temple university in 2015
- Nov 2018Seed$2.6M
- May 2017Seed$950K
- Nov 2015Seed$670K
- Oct 2015Seed—
#12
Funding Raised · Philadelphia, Pennsylvania · founded 1988$2.4Mraised▾
Developer and manager of affordable, equitable, safe, and sustainable homes. The organization focuses on providing residences that support individuals and families while also strengthening the surrounding communities. It offers property management and resident services. The entity also pursues innovative solutions related to its core activities.
- Oct 2011Grant (prize money)$67.7K
- Aug 2011Grant (prize money)—
- May 2011Grant (prize money)—
- Mar 2011Grant (prize money)$201.7K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Sustainability Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Climate Adaptation is moving in the United States
A read on the academic research around Climate Adaptation — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,953 United States-affiliated papers.
- Columbia University52
- University of North Carolina at Chapel Hill43
- Arizona State University42
- Texas A&M University42
- Purdue University West Lafayette35
- Flood myth4→56
- Climate change6→47
- Flooding (psychology)2→23
- Climate resilience1→16
- Flood mitigation2→14
- Flood myth50→178
- Climate change35→155
- Flooding (psychology)18→97
- Resilience (materials science)10→84
- Psychological resilience12→55
- Climate change71→449
- Resilience (materials science)17→139
- Flood myth36→158
- Psychological resilience13→115
- Climate resilience14→92
Where climate adaptation is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing climate adaptation patents in the United States
United States climate adaptation patent filing is cooling — 28 filings from 19 assignees (2016–2025), led by ILC Dover, Garcia Rogerio, Serralta Denset; annual filings 6→1.
- ILC Dover20
- Garcia Rogerio4
- Serralta Denset4
- Zesty AI2
- Yodock GUY1
- Mckee TONY RAY1
- Ballard Tristan1
- Cooper Matthew1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.