Best Sustainability Tech Companies in Raleigh, United States
The 48 best Sustainability Tech companies in Raleigh, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Sprout Pharmaceuticals.
Our analysis of 84 Sustainability Tech companies
$19.4b in tracked funding; 85% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Sustainability Tech companies in Raleigh
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sprout Pharmaceuticals Developer of drugs for hypoactive sexual desire disorder in women | $175M | 20 mo ago | Acquired | — | 2011 | Cart FunctionalitySquarespace CommerceSquarespace+15 | — | — |
| 2 | Locus Biosciences Developer of therapeutics for infectious disease and inflammatory indications | $67M | 30 mo ago | Series B | Paul Garofolo Chief Executive Officer | 2015 | WordPress Block EditorWordPressMySQL+24 | 60 patents Engineered CRISPR‑enhanced bacteriophage therapeutics targeting antibiotic‑resistant bacterial infections | — |
| 3 | Tantalus Communication technology provider for smart grids 53Funding top 22%News top 22%Growth top 33%Moat top 48% All 9 signals ▾Fundingtop 22% Newstop 22% Growthtop 33% Moattop 48% Techtop 49% Marketbottom 44% Globalbottom 44% Talentbottom 40% Partnersbottom 35% Funding: Raised $58.7M across 8 rounds · 8 rounds over 22 yrs (0.4/yr) News: 11 BI events in 12 mo (of 29 tracked, 7 types) · +1000% YoY rank vs industry peers · Fliar Intelligence Index 53/100 | $59M | 6 mo ago | Public | Ramatoulie Deen Founder/Executive Director | 1989 | WordPressApple iCloud MailMySQL+22 | — | 1 launch |
| 4 | Second Nature Provider of resident benefits packages for property managers and owners | $36M | 76 mo ago | Series C | Thad Tarkington Co-Founder & CEO | 2012 | WebflowApple iCloud MailGoogle Workspace+31 | 27 patents Modular, collapsible and variable air filter assemblies for HVAC and industrial ventilation. | — |
| 5 | Marius Pharmaceuticals Developer of an proprietary oral testosterone replacement therapy platform | $33M | 58 mo ago | Series B | Himanshu Shah Co-Founder | 2017 | WordPressMySQLPHP+17 | — | — |
| 6 | GreenPlaces Online platform to calculate and offset the carbon footprint | $21M | 23 mo ago | Series A | — | 2021 | WordPressMySQLPHP+19 | — | — |
| 7 | Power Analytics Provider of energy monitoring systems and microgrid integration systems | $6M | 203 mo ago | Acquired | Adib Nasle Co-Founder & ex-President | 1983 | — | 77 patents Real-time AI-driven monitoring, forecasting, and safety analytics for electrical power distribution. | — |
| 8 | Passage Home Non-profit organization focused on poverty | $4M | 15 mo ago | Funding Raised | Seth Friedman CEO | 1991 | WordPress Block EditorElementorWordPress+21 | — | — |
| 9 | Agile Sciences Develops anti-bacterial small molecules | $2M | 74 mo ago | Deadpooled | — | 2007 | — | — | — |
| 10 | Benanova Sustainable materials company creating nature-inspired colloid solutions for diverse markets | $2M | 25 mo ago | Funding Raised | Alexander Richter Co-Founder | 2013 | — | 8 patents Advanced colloidal formulations for agrochemical delivery (pesticides/fertilizers). | — |
| 11 | GridBridge Power delivery solutions improving utilities' operating performance at the grid edge | $500K | 134 mo ago | Acquired | Chad Eckhardt President & CEO | 2012 | WordPress Block EditorwpBakeryElementor+20 | 29 patents Flexible grid‑edge energy management and routing for electrical distribution networks | — |
| 12 | Flux Hybrids Developer of conversion kits for multi-category electric vehicles | $467K | 52 mo ago | Seed | Cody Biedermann Co-Founder & CTO | 2019 | WixSentryBootstrap+11 | — | — |
| 13 | Avana Health Developer of treatments for women health | $128K | 10 mo ago | Seed | Peter Pacult Co-Founder & CEO | 2021 | Cart FunctionalitySquarespace CommerceSquarespace+10 | — | — |
Top 12 Sustainability Tech companies in Raleigh
#1
Public · Raleigh, North Carolina · founded 1989 · 42 employees$58.7Mraised▾
Tantalus Systems is a provider of multi-purpose smart grid solutions platform for advanced metering, demand response, and distribution automation. Offers TUNet, a WAN/LAN/HAN communications system that enables electric, water, and gas municipal and cooperative utilities to automate processes, improve business operations, and deliver customer services. It also works on multi-commodity networks like IP based, Mesh and Star, etc.
- Feb 2026Post IPO$156.7K
- May 2024Post IPO$366.5K
- Feb 2017Series B$6M
- Dec 2016Conventional Debt$5.1M
#2
Acquired · Raleigh, North Carolina · founded 2011 · 31 employees$174.6Mraised▾
Sprout Pharmaceuticals has developed drugs for women's health. The company has developed an FDA-approved non-hormonal pill called ADDYI to cure Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women.
- Dec 2024Series D$10.6M
- Apr 2023Series D$7.1M
- Aug 2022Series D$28M
- May 2022Series D$25.1M
#3
Funding Raised · Raleigh, North Carolina · founded 1991 · 51 employees$3.6Mraised▾
Passage Home is a nonprofit working to break the cycle of poverty for the communities it serves in Wake County. We go about our mission by developing people, developing places and strengthening communities. You can learn more about what we mean by that on our website, www.passagehome.org. We provide a holistic approach of comprehensive case management through our programs and services, supporting the needs of families across Wake County.
- May 2025Grant (prize money)$314.1K
- Mar 2025Grant (prize money)$579.5K
- Apr 2014Grant (prize money)$192.1K
- Apr 2012Grant (prize money)—
#4
Series A · Raleigh, North Carolina · founded 2021 · 35 employees$21.5Mraised▾
Online platform to calculate and offset the carbon footprint. Its platform helps companies to calculate carbon emissions from the daily commute, electric lighting, data servers, air travels, and others. It invests in carbon negative projects to offset the carbon footprint.
- Aug 2024Series A$3.3M
- Jun 2023Series A$13.2M
- Oct 2022Series A$4M
- Jul 2021Seed$975K
#5
Series B · Raleigh, North Carolina · founded 2015 · 74 employees$67.3Mraised▾
Developer of therapeutics for infectious disease and inflammatory indications. The company has developed a platform to design and deliver custom CRISPR-Cas systems directly to specific bacteria and enables the development of antimicrobials for infectious diseases.
- Jan 2024Grant (prize money)$23.9M
- May 2022Series B$35M
- Oct 2021Conventional Debt—
- Nov 2020Conventional Debt$20M
#6
Seed · Raleigh, North Carolina · founded 2021 · 6 employees$127.5Kraised▾
Developer of treatments for women health. The company aims to provide women with treatments for Postpartum Hemorrhage (PPH) and Abnormal Uterine Bleeding (AUB) that are accessible anywhere in the world.
- Sep 2025Seed$2.8M
- Nov 2022Seed$127.5K
#7
Funding Raised · Raleigh, North Carolina · founded 2013$1.7Mraised▾
Sustainable materials company creating nature-inspired colloid solutions for diverse markets. The company develops cost-efficient, environmentally benign particle systems from natural materials using sustainable processes. They focus on creating functionally active and sustainable materials based on bio-degradable and bio-renewable resources. Their innovations aim to have a global impact, offering sustainable products with advanced functionality for lasting benefits. The company is committed to innovation, translating scientific advances into robust benefits. They develop renewable and biodegradable particle delivery systems and superhydrophobic coatings. Their materials are applicable in agriculture for reducing pesticide use, in textile finishes for improved water repellency, and in filtration for enhanced efficiency. The company aims to develop green innovations that positively impact the environment and help mitigate global warming and climate change. They commercialize high-performance, safe, and sustainable material solutions.
- Jul 2024Grant (prize money)$175K
- Aug 2020Grant (prize money)$256K
- Apr 2020Grant (prize money)$800K
- Jan 2020Grant (prize money)$256K
#8
Series B · Raleigh, North Carolina · founded 2017 · 20 employees$32.6Mraised▾
Marius Pharmaceuticals is developing a proprietary oral testosterone replacement therapy platform. The lead candidate of the company, testosterone undecanoate. It gets absorbed through the intestinal lymphatic system and bypasses the issues related to oral testosterone absorption via the portal vein.
- Oct 2021Series B$6M
- May 2019Series B$5.6M
- Series B$21M
#9
Series C · Raleigh, North Carolina · founded 2012 · 247 employees$36.2Mraised▾
Provider of resident benefits packages for property managers and owners. These packages bundle perks designed to improve resident satisfaction and property value. Benefits include renters insurance, credit building, air filter delivery, and on-demand pest control. The packages integrate with existing property management software to streamline operations.
- Mar 2020Series C$16.4M
- Oct 2018Series B$6.9M
- Jul 2017Series B$7M
- Aug 2016Series A—
#10
Deadpooled · Raleigh, North Carolina · founded 2007 · 11 employees$2.3Mraised▾
Agile Sciences was founded to provide commercial solutions to those industries plagued by the effects of biofilms. They identified ageliferin secreted by marine sponge Agelas conifera, which works against both gram positive and gram negative bacteria. To increase antimicrobial efficacy the company has started developing a library of pharmaceutically active small molecules ( 2-aminoimidazole) with antimicrobial activity.The compound inhibits the ability of the bacteria to sense and respond to the environment (bacterial two component systems which usually involve histidine kinases), thereby affecting the formation of biofilms and other protective layerings.
- May 2020Seed$1M
- Sep 2011Grant (prize money)$428.2K
- Nov 2010Grant (prize money)$150K
- Aug 2010Grant (prize money)$251.8K
#11
Acquired · Raleigh, North Carolina · founded 1983 · 23 employees$6Mraised▾
Power Analytics (fka EDSA Micro Corporation) develops and supports electrical power system design, simulation, and analytics software solutions. The company's products include Paladin DesignView - a real-time scientific visualization software tool that lets users to create detailed dashboards, Paladin Gateway - a power system data integration platform, Paladin Live - a power system analytics solution, Paladin Microgrid Power Management System - a software platform for the online management and control of hybrid power infrastructure areas, Paladin WSM - a white space management solution that integrates facilities and IT technology to enhance the management of power, space, and cooling, Designbase Xi - a cloud-based engineering software solution and EnergyNet - a software solution that enables integrated system planning, grid operations, and market transactions, as well as models, optimizes, monitors, and transacts business with energy systems. It serves data and network operations centers, manufacturing plants, nuclear power facilities, deep sea oil platforms, aircraft carriers, submarines, federal aviation administration networks, and other complex structures worldwide.
- Sep 2009Series B$384.2K
- Apr 2008Series B$5.5M
#12
Seed · Raleigh, North Carolina · founded 2019 · 6 employees$467Kraised▾
Developer of conversion kits for multi-category electric vehicles. The company develops conversion kits for commercial vehicles, HEV, PHEV, consumer vehicles, etc. These kits include battery capacity 2.6Kwh, lithium-ion battery, 60V system voltage, electric drive unit, etc. It offers features like claims to optimize fuel efficiency, integrates with drivetrain system, remote data acquisition, etc.
- Apr 2022Seed$467K
- Oct 2021Grant (prize money)$5K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Sustainability Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Climate Adaptation is moving in the United States
A read on the academic research around Climate Adaptation — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,953 United States-affiliated papers.
- Columbia University52
- University of North Carolina at Chapel Hill43
- Arizona State University42
- Texas A&M University42
- Purdue University West Lafayette35
- Flood myth4→56
- Climate change6→47
- Flooding (psychology)2→23
- Climate resilience1→16
- Flood mitigation2→14
- Flood myth50→178
- Climate change35→155
- Flooding (psychology)18→97
- Resilience (materials science)10→84
- Psychological resilience12→55
- Climate change71→449
- Resilience (materials science)17→139
- Flood myth36→158
- Psychological resilience13→115
- Climate resilience14→92
Where climate adaptation is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing climate adaptation patents in the United States
United States climate adaptation patent filing is cooling — 28 filings from 19 assignees (2016–2025), led by ILC Dover, Garcia Rogerio, Serralta Denset; annual filings 6→1.
- ILC Dover20
- Garcia Rogerio4
- Serralta Denset4
- Zesty AI2
- Yodock GUY1
- Mckee TONY RAY1
- Ballard Tristan1
- Cooper Matthew1