Best Sustainability Tech Companies in Wisconsin, United States
The 78 best Sustainability Tech companies in Wisconsin, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Encorp.
Our analysis of 84 Sustainability Tech companies
$19.4b in tracked funding; 85% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Sustainability Tech companies in Wisconsin
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Stage | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Encorp Demand response and smart communications systems | $53M | 260 mo ago | 60 | — | — | Public | — | — |
| 2 | Elucent Medical Wireless Brease Marker for Breast Cancer Treatment | $50M | 26 mo ago | 11 | Laura King Co-Founder & CEO | — | Series C | — | — |
| 3 | FluGen Developing innovative influenza vaccines with broad immune response and supra-seasonal protection | $34M | 58 mo ago | 12 | — | — | Series A | 136 patents Influenza vaccine design: mutant strains, immunogenic compositions, and thermostable formulations. | — |
| 4 | Telkonet Provider of HVAC energy management solutions for commercial spaces | $25M | 124 mo ago | 27 | — | WordPressMySQLPHP+25 | Acquired | 16 patents Patents concentrated in electrical & electronics | — |
| 5 | Atterx Biotherapeutics Developing novel solutions to prevent and treat antibiotic-resistant bacterial infections | $12M | 122 mo ago | — | Steve Watt CEO | — | Series A | 8 patents Live bacterial therapeutics and small-colony variants for wound and surface healing | — |
| 6 | PegEx Cloud-based waste and material management software | $11M | 82 mo ago | 18 | — | — | Series B | — | — |
| 7 | Gorman & Company Developer of affordable homes | $10M | 75 mo ago | 85 | — | WordPressMySQLPHP+24 | Series A | 14 patents Advanced road resurfacing machinery and stress‑absorbing membrane materials for pavement rehabilitation | — |
| 8 | Monaire AI-enabled HVAC and refrigeration management solutions | $8M | 12 mo ago | — | Rahul Subramany Co-Founder | — | Seed | — | — |
| 9 | EnSync Manufactures intelligent energy storage systems | $7M | 87 mo ago | 64 | — | — | Deadpooled | 59 patents Hybrid energy storage management and power flow control for renewable and backup systems | — |
| 10 | Appleton Housing Authority Affordable housing developers | $5M | 9 mo ago | — | — | WordPressMySQLPHP+13 | Funding Raised | — | — |
| 11 | AmebaGone Novel technology fighting antimicrobial resistance with amoebae to control pathogenic microbes | $4M | 68 mo ago | 6 | Marcin Filutowicz Founder | — | Funding Raised | 17 patents Live amoeba-based therapeutics and anti‑biofilm microbial agents for medical applications | — |
| 12 | Prodesse Prodesse develops molecular diagnostic reagents for infectious disease applications. | $4M | 251 mo ago | — | Stephen MacMillan CEO & Chairman | — | Acquired | — | — |
| 13 | Ebullient Offers cooling systems for data centers | $3M | 112 mo ago | 9 | — | — | Series A | 69 patents Advanced two-phase cooling heat sink modules for high‑power electronics thermal management. | — |
| 14 | Grestech Provider of solutions to capture atmospheric CO2 | $3M | 190 mo ago | — | Gary Comer Co-Founder | — | Series A | — | — |
| 15 | NanoAffix Develops sensors for detection of water quality | $3M | 24 mo ago | 7 | Junhong Chen Founder & CEO | — | Funding Raised | — | — |
| 16 | Isomark Breath analyzer for infectious disease detection | $2M | 41 mo ago | 10 | Joe Kremer CEO | — | Series A | — | — |
| 17 | DANE COUNTY HOUSING AUTHORITY Operator of housing programs providing assistance and resources to applicants | $2M | 13 mo ago | — | — | WixSentryBootstrap+11 | Funding Raised | — | — |
| 18 | Stonehouse Water IoT enabled water purification system manufacturer | $2M | 102 mo ago | 11 | Hensley Foster CEO & President | — | Seed | — | — |
| 19 | Earth Repair Provider of carbon capture solution | $2M | 30 mo ago | — | Bu Wang Co-Founder | — | Seed | — | — |
| 20 | EDCS Power Platform that designs and builds equipment to improve power efficiency in data centers | $1M | 138 mo ago | 4 | John Meinecke Co-Founder & CEO | — | Deadpooled | — | — |
| 21 | Wellntel Provider of cloud-based groundwater monitoring network deployers | $1M | 97 mo ago | 10 10 → 11 (+10%) | Nicholas Hayes Co-founder and Director | — | Seed | 3 patents Oil and gas wellhead water quality monitoring sensors and systems | — |
| 22 | AkitaBox SaaS for building inspection services. | $1M | 122 mo ago | 35 | — | — | Seed | 2 patents Enterprise capital management software for custom assemblies and schedulable cost lines | — |
| 23 | bluDiagnostics Saliva-based fertility tests for women | $1M | 97 mo ago | 6 | Douglas Weibel Co-Founder | — | Seed | 7 patents Lateral‑flow saliva test devices for quantitative analyte detection | — |
| 24 | Quietyme Smart solutions for managing noise, improving patient experience, and property management | $980K | 143 mo ago | 3 | John Bialk Founder & CEO | — | Seed | 3 patents Real-time disturbance detection and predictive analytics for industrial control systems | — |
| 25 | Habitat for Humanity Developer of affordable houses | $650K | 68 mo ago | 38 | Millard Fuller Co-Founder | WordPressMySQLPHP+28 | Funding Raised | — | 1 job opening · 1 internship · 1 award |
| 26 | Estrigenix Developer of estrogen-based therapeutics women health | $598K | 17 mo ago | 4 | — | — | Funding Raised | — | — |
| 27 | ChloBis Water Developer of a desalination battery for the treatment of waste water | $512K | 54 mo ago | — | Kyoung-Shin Choi Co-Founder | — | Funding Raised | — | — |
| 28 | OneEvent Technologies Patented predictive analytics engine for building and home monitoring | $415K | 117 mo ago | 892 | Kurt Wedig Founder & CEO | Cart FunctionalityWordPressMySQL+30 | Seed | 18 patents Patents concentrated in computing, sensing & instrumentation | — |
| 29 | Pattern Genomics Specializes in application of large-scale bioinformatics sequence analysis for molecular assay design | $150K | 159 mo ago | 2 | — | — | Acquired | — | — |
Top 12 Sustainability Tech companies in Wisconsin
#1
Funding Raised · Appleton, Wisconsin · founded 2000$4.8Mraised▾
Affordable housing developers
- Sep 2025Grant (prize money)$490K
- May 2025Grant (prize money)$490K
- Mar 2025Grant (prize money)$93.4K
- Mar 2025Grant (prize money)$305.6K
#2
Seed · Madison, Wisconsin · founded 2020$7.6Mraised▾
AI-enabled HVAC and refrigeration management solutions. It provides solution to monitor and prevent refrigeration outages, reduce wasted supplies and dangerous food spoilage.
- 2025Seed$4M
- Mar 2024Seed$3.5M
- Dec 2023Seed$4.1M
#3
Funding Raised · Wisconsin Rapids, Wisconsin · founded 2000$1.8Mraised▾
Operator of housing programs providing assistance and resources to applicants. It manages various housing programs, including voucher programs and owned housing. The organization offers information on waiting lists, applicant preferences, and eligibility requirements. It also provides resources for families and landlords, ensuring compliance with relevant regulations.
- May 2025Grant (prize money)$220.6K
- Mar 2025Grant (prize money)$90K
- Mar 2025Grant (prize money)$163.1K
- Mar 2012Grant (prize money)$97.4K
#4
Series C · Brookfield, Wisconsin · founded 2014 · 11 employees$49.7Mraised▾
Developer of a breast cancer detection system designed to eliminate the need for a metal clip. The company's detection system shows tumor margins during surgical excision, as well as simplifies breast cancer treatment by making procedures accessible and affordable, enabling surgeons to preserve their patient's breast as much as possible while removing cancer.
#5
Funding Raised · Milwaukee, Wisconsin · founded 2018 · 4 employees$598.1Kraised▾
Developer of estrogen-based therapeutics women health. The company's product line include EGX-358, is a potent and selective agonist of the estrogen receptor beta protein, which enhances memory formation in a mouse model of menopause.
- Jan 2025Grant (prize money)$299.1K
- Sep 2022Grant (prize money)$299.1K
#6
Funding Raised · Wauwatosa, Wisconsin · founded 2010 · 7 employees$2.6Mraised▾
NanoAffix has developed sensors for detecting the quality of water through patent-pending technology. The sensor is primarily a FET device with a Graphene oxide sensing channel and specific molecules acting as probes. The technology acts as an electronic sensing platform that can be used for the detection of various contaminants in water. The sensor is currently in a working prototype stage.
- Jun 2024Grant (prize money)$300K
- Jun 2024Grant (prize money)$293.8K
- Sep 2020Grant (prize money)—
- Aug 2017Grant (prize money)$1.5M
#7
Series A · Madison, Wisconsin · founded 2007 · 12 employees$34.5Mraised▾
Developing innovative influenza vaccines with broad immune response and supra-seasonal protection. The company focuses on creating more effective vaccines against influenza and respiratory diseases. Their M2SR Vaccine Platform aims to revolutionize the influenza market by addressing unmet needs in flu prevention, such as consistent efficacy and protection against virus drift. The flagship candidate, M2SR, is an intranasal vaccine designed to stimulate mucosal, humoral, and cellular immunity. Long-term research and development plans include potential applications for protection against COVID-19 and other respiratory diseases like RSV. The company aims to provide broad immune response, especially at the site of infection, and protection against drifted strains. They are dedicated to advancing influenza vaccine technology and introducing new solutions for influenza and COVID-19 protection.
- Aug 2021Grant (prize money)$11.4M
- May 2020Series A$8.2M
- Aug 2019Grant (prize money)$4.2M
- Nov 2018Venture Debt$5.6M
#8
Public · Holcombe, Wisconsin · founded 1992 · 60 employees$53Mraised▾
Encorp manufactures integrated hardware and software systems for the distributed energy market. It provides a suite of software applications that allows users to control and monitor distributed energy assets and demand response. It also provides family of controls The Gold Box™ for single or multiple generators, the Utility Power Control™ for utility interconnect control, and the Meter Monitor Control™ for metering and monitoring applications for smart communications. It caters its products and services for micro grid to connect distributed energy systems.
- Oct 2004Series D$1.4M
- Apr 2004Series D$7.1M
- Oct 2001Series D$38.1M
#9
Funding Raised · Pine River, Wisconsin · founded 1998$20Kraised▾
Developer of radiant heating system designed for multiple heat sources. The system streamlines in-floor heating installation, replacing complex plumbing with a compact solution. It works with electricity, heat pumps, and solar energy. The company offers consultation services to help build facilities.
- Jun 2025Grant (prize money)$20K
#10
Seed · Madison, Wisconsin · founded 2022$1.5Mraised▾
Provider of carbon capture solution. It offers a low carbon cement replacement solution that removes CO2 from the atmosphere.
- Dec 2023Seed$1.5M
#11
Acquired · Milwaukee, Wisconsin · founded 1999 · 27 employees$24.6Mraised▾
Provider of HVAC energy management solutions for commercial spaces. It offers EcoSmart products, along with the EcoCentral management platform that helps to reduce energy consumption, HVAC runtime, and utility costs in most building environments. Its app is available for Android devices.
- Feb 2016Grant (prize money)—
- Oct 2014Conventional Debt$2M
- Apr 2011Series A$1.4M
- Aug 2010Series A$1.3M
#12
Series B · Dane, Wisconsin · founded 2012 · 18 employees$11Mraised▾
Cloud-based waste and material management software. It offers cloud-based solutions for waste stream management, reporting, and compliance. It provides visibility, integration, and control for companies managing hazardous and non-hazardous waste and materials.
- Aug 2019Series B$1.2M
- May 2018Series B$8M
- Apr 2018Conventional Debt—
- Apr 2018Seed—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Sustainability Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
What Wisconsin researches in climate adaptation
- University of Wisconsin–Madison13
- Medical College of Wisconsin2
- University of Wisconsin–Milwaukee1
- University of Wisconsin–Eau Claire1
- University of Wisconsin Health1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.