Best Traditional Medical Devices Companies in Pennsylvania, United States
The 42 best Traditional Medical Devices companies in Pennsylvania, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Flower Orthopedics.
Our analysis of 50 Traditional Medical Devices companies
$5.7b in tracked funding; 88% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Traditional Medical Devices companies in Pennsylvania
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Flower Orthopedics Ready-for Surgery treatment concepts for Bone Fixation | $9M | 121 mo ago | Acquired | — | 2012 | — | 31 patents Advanced bone fixation hardware: plates, screws, external fixators, and suture anchor tools. | — |
| 2 | AIONX Antimicrobial technology to limit surface-dwelling microbes | $6M | 66 mo ago | Series A | — | 2006 | — | — | — |
| 3 | Aevumed Manufacturer of phantom for tendon repair | $5M | 56 mo ago | Seed | Saif Khalil Founder & CEO | 2013 | — | 19 patents Knotless orthopedic suture anchors and 3D‑printed tissue scaffolds for bone‑tendon repair | 3 launchs |
| 4 | NEXGEL Manufacturer of transdermal drug delivery patches | $2M | 65 mo ago | Public | Adam Levy CEO | 1997 | WordPressMySQLPHP+11 | 5 patents Medical drapes and dressings designed for fragile skin protection in surgeries | — |
| 5 | Osciflex LLC Developer of novel therapies for venous disease prevention and treatment. | $2M | 86 mo ago | Funding Raised | — | 2017 | — | 8 patents Medical compression devices for rapid thrombosis prevention in patients | — |
| 6 | LensRxLab Manufacturer of ophthalmic devices | $830K | 28 mo ago | Seed | Jennifer Marin Co-Founder & CCO | 2023 | — | — | — |
| 7 | OYS Mobility Custom manufacturer of prosthetic devices | $256K | 69 mo ago | Funding Raised | Princess O CEO | 2020 | — | — | — |
| 8 | Gus Gear Manufacturer of central lines, ostomy pouches, feeding tubes and medical gear | $100K | 66 mo ago | Seed | Sarah Palya Founder & CEO | 2008 | WordPressMySQLPHP+30 | — | 1 job opening |
Top 12 Traditional Medical Devices companies in Pennsylvania
#1
Seed · Philadelphia, Pennsylvania · founded 2023$830Kraised▾
Manufacturer of ophthalmic devices
- Apr 2024Seed$830K
#2
Seed · Wayne, Pennsylvania · founded 2013 · 5 employees$5.1Mraised▾
Manufacturer of phantom for tendon repair
- Dec 2021Seed$3M
- Sep 2020Seed$1.5M
- Apr 2018Seed$264K
- Nov 2013Seed$305K
#3
Series A · Hershey, Pennsylvania · founded 2006 · 4 employees$5.8Mraised▾
AIONX aims to limit certain surface-dwelling microbes and the markets in focus include healthcare, consumer, industrial, and defense. The company has developed a technology that continuously releases silver and copper ions from the surfaces of treated products; the metals have been shown to be effective against most known human pathogens and, in fact, are the active agent used in many medical devices designed to reduce bacteria and infections. Thomas A Fuller, the Founder of this company, has conducted research on "Developing an engineered antimicrobial/prophylactic system using electrically activated bactericidal metals", "Prophylactic Bactericidal Orthopedic Implants – Animal Testing Study", etc.
- Feb 2021Series A$700K
- Feb 2019Series A$3.8M
- Jan 2013Seed$494.9K
- Jun 2011Seed$500.2K
#4
Acquired · Philadelphia, Pennsylvania · founded 2012 · 50 employees$9.3Mraised▾
Flower Orthopedics develops cost-effective, safe and efficient, Ready-for-Surgery treatment concepts for bone fixation. They developed FlowerCube, a complete and standardized, procedure-based, bone-fixation concept, which contains all the requisite implants and instruments for a procedure. Partnered with Zrinski to design and manufacture sterile Flower implants and single-use Flower Instrument Kits.
- Jul 2016Series C$2.3M
- Nov 2014Series C$4.5M
- Apr 2014Series A$2.5M
#5
Public · Langhorne, Pennsylvania · founded 1997 · 12 employees$2.4Mraised▾
Manufacturer of transdermal drug delivery patches
- Mar 2021Series A$2M
- Aug 2020Unattributed$395.1K
#6
Funding Raised · Philadelphia, Pennsylvania · founded 2017 · 2 employees$2.1Mraised▾
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- Jun 2019Grant (prize money)$1.8M
- Feb 2019Grant (prize money)$225K
#7
Funding Raised · Philadelphia, Pennsylvania · founded 2020 · 2 employees$256Kraised▾
Developer of prosthetic technology designed to make healthcare and assistive devices accessible to anyone with limb loss or limb deformity. The company's technology uses a computational approach to digitize the biomechanical design required to develop custom prosthetic devices, enabling healthcare professionals to offer prosthetic limb designs.
- Dec 2020Grant (prize money)$256K
#8
Seed · Pittsburgh, Pennsylvania · founded 2008 · 6 employees$100Kraised▾
Manufacturer of wearable securement clothing intended to protect implanted medical devices in the body such as central catheters and feeding tubes. The company's platform manufactures securement and covers for medical devices such as central lines, ostomy pouches, feeding tubes, and other medical gear that is constructed with quality fabrics and uses a system of securement to affix the central venous access device and prevent line pulls from damaging the catheter, enabling patients to enhance their quality of life and live their lives to the fullest irrespective of any medical challenge.
- Feb 2021Seed$100K
#9
Seed · Philadelphia, Pennsylvania · founded 2017 · 2 employees$25Kraised▾
Manufacturer of breastfeeding pumping accessories
- Sep 2021Seed$25K
#10
Funding Raised · Pittsburgh, Pennsylvania · founded 2017 · 4 employees$50Kraised▾
Operator of a medical device company intended to provide vascular graft and shunt designs engineered to mimic native arteries and prevent thrombosis. The company's platform is integrated with a new nature-inspired, surface technology into the design of the synthetic vascular reconstruction to have a doubled implant lifetime due to their ability to harness nature's mechanisms and keep blood clot buildup from depositing on the blood-contacting surface, enabling patients, surgeons, and hospitals to have preferred outcomes at affordable costs.
- Feb 2020Conventional Debt$50K
#11
Acquired · Lackawanna, Pennsylvania · founded 1985 · 288 employees$49.9Kraised▾
Manufacturer of power lift chair recliners, mobility scooters & wheelchairs
- Sep 2009Grant (prize money)$49.9K
#12
Acquired · Plymouth Meeting, Pennsylvania · founded 1913 · 149 employees—raised▾
Manufacturer of dental medical devices
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Traditional Medical Devices coverage by sub-theme.
Regulatory-risk over time flat
Funding & growth over time
funding flat · growth rising
What Pennsylvania researches in medical devices
- University of Pennsylvania15
- Pennsylvania State University8
- California University of Pennsylvania4
- University of Pennsylvania Health System3
- Hospital of the University of Pennsylvania1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.