Best Trending Themes in Life Sciences Tech Companies in United States
The 139 best Trending Themes in Life Sciences Tech companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Evolved By Nature.
Tracking the best Trending Themes in Life Sciences Tech companies across the United States, this directory covers 139 firms with $306M in total disclosed funding. Evolved By Nature leads the pack at $190M raised, a figure that dwarfs the rest of the field. Metaphore sits second at $50M, with HistoWiz at $34M rounding out the top three. No unicorns yet, but the capital concentration is real. Backers like HHS, the National Science Foundation, and Adams Capital Management are the names showing up repeatedly across portfolio pages, which tells you something about where institutional confidence is sitting right now.
So what's pulling investment toward this sector? Demand drivers are stacking: next-generation research frameworks, regulatory compliance pressure, and IP protection are all pushing organizations to find smarter tech solutions. I'd also point to the mobile signal, where median install growth is running at roughly +43% year-over-year across healthcare and life sciences apps, a number that signals genuine end-user adoption, not just enterprise spend. Extreme weather themes are threading into health-tech conversations too, particularly around life-threatening weather alerts and emergency advisory infrastructure, as public health and climate risk increasingly overlap. If you're mapping where Trending Themes in Life Sciences Tech money moves next in the United States, watch the intersection of regulatory tailwinds and that mobile growth curve.
- LifeSciencesIntelligence
- EVERSANA
Ranked: Best Trending Themes in Life Sciences Tech companies in United States
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Evolved By Nature Developer of bioactive peptides derived from silk protein for skincare | $190M | 47 mo ago | Series C | Gregory Altman Co-Founder & CEO | 2013 | — | 230 patents Silk-based biopolymers for performance textiles, cosmetics, and hyaluronic‑acid medical fillers | 1 award |
| 2 | Metaphore Provider of machine language and computational platform for drug discovery 42Funding top 23%Talent top 28%Moat top 42%AI top 45% All 7 signals ▾Fundingtop 23% Talenttop 28% Moattop 42% AItop 45% Globalbottom 36% Techbottom 35% Marketbottom 31% Funding: Raised $50.0M across 1 rounds · 1 rounds over 3 yrs (0.3/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 42/100 | $50M | 2 mo ago | Series C | Noubar Afeyan Co-Founder | 2021 | WebflowMicrosoft 365jQuery+4 | — | — |
| 3 | HistoWiz We are hiring: https://histowiz.workable.com/ About HistoWiz HistoWiz is an innovative company dedicated to… | $34M | 56 mo ago | Series A | — | 2012 | SentryMUIReact+19 | 8 patents AI-powered automated tagging and quality control for digital histology slide images | — |
| 4 | SilcsBio Provides software and services for computer driven drug design | $7M | 14 mo ago | Funding Raised | — | 2012 | WordPressMySQLPHP+24 | — | — |
| 5 | Serotiny Provider of drug research and development services for cell & gene therapies | $7M | 39 mo ago | Series A | — | 2009 | — | 12 patents Engineered conditional immune cell receptors for targeted immunotherapy applications. | — |
| 6 | MetaMe Health Provider of digital therapeutics for gut health | $6M | 26 mo ago | Seed | — | 2015 | — | — | — |
| 7 | Bioleap Provider of computational fragment-based technology for drug discovery | $5M | 153 mo ago | Series A | Wayne Mitchell CEO | 2002 | — | 15 patents Industrial heat recovery and process energy integration for cooking, drying, and distillation | — |
| 8 | Integrative Bioinformatics Provider of bioinformatics software and consulting for biological pathway modeling | $4M | 156 mo ago | Funding Raised | Robert Phair Co-Founder & Chief Science Officer | 2002 | — | — | — |
| 9 | OncoTree DTS Developing vascular informatics for oncology research, drug discovery and translational development | $2M | 170 mo ago | Deadpooled | Raul Brauner Founder & CEO | 2010 | — | — | — |
| 10 | RNAV8 Bio Developer of RNAs to treat various diseases | $600K | 41 mo ago | Seed | Devan Shah Founder & CEO | 2022 | — | — | — |
| 11 | HTI Provider of an AI-based bioimaging and molecular modeling tool for drug discovery | $225K | 75 mo ago | Funding Raised | Tuan Phamdo Founder & CEO | 2016 | — | 114 patents Patents concentrated in computing, sensing & instrumentation | — |
Top 12 Trending Themes in Life Sciences Tech companies in United States
#1
Series C · Cambridge, Massachusetts · founded 2021 · 30 employees$50Mraised▾
Provider of machine language and computational platform for drug discovery. The company uses biomimicry and machine learning to unleash the transformational medicinal potential of functional molecular mimics. The MIMiC platform, developed by the company is a computationally driven bioplatform for developing novel therapies in which function, specificity, and selectivity may be optimized.
- Apr 2026Series C—
- May 2023Series C$50M
#2
Funding Raised · Baltimore, Maryland · founded 2012 · 7 employees$7Mraised▾
SilcsBio provides software and services for computer driven drug design. Its products include CGENFF to perform simulations on a system that contains a small organic molecule; SILCS, fragment-based drug design platform.
- Mar 2025Grant (prize money)$1.8M
- Nov 2021Grant (prize money)$1.8M
- Mar 2019Grant (prize money)$2M
- Mar 2015Grant (prize money)$1.5M
#3
Series C · Medford, Massachusetts · founded 2013 · 101 employees$190Mraised▾
Developer of bioactive peptides derived from silk protein for skincare. These peptides are clinically proven and naturally derived. The company creates ingredients designed to improve product performance and sustainability. It offers bioactive peptides and hydrogels for healthier skin. The peptides support skin restoration after damage and UV exposure.
- Jun 2022Series C$120M
- Dec 2021Series B$70M
- Jun 2019Series A—
#4
Seed · Chicago, Illinois · founded 2015 · 8 employees$6Mraised▾
MetaMe Health provides digital therapeutics for gastrointestinal conditions. Regulora, the company's flagship platform, provides relief by digitizing a standardized Brain-Gut therapy approach that has been clinically proven to be effective in reducing Irritable Bowel Syndrome (IBS) symptoms. The platform is a software-based product that engages patients, tracks adherence, facilitates clinician engagement, and safely delivers consistent health outcomes in randomized controlled clinical trials.
- Mar 2024Conventional Debt$140.5K
- May 2023Conventional Debt$235K
- Mar 2022Seed$2.2M
- Nov 2021Conventional Debt$65K
#5
Series A · Brooklyn, NY · founded 2012 · 85 employees$33.6Mraised▾
We are hiring: https://histowiz.workable.com/ About HistoWiz HistoWiz is an innovative company dedicated to accelerating pathology-based research. HistoWiz provides fast, global access to digital whole-slide images, online collaboration tools, low-cost data management, and experimental pathology expertise. The web-based platform accelerates information exchange among medical scientists and research pathologists. HistoWiz's mission is to fight cancer cooperatively instead of individually by connecting scientists and pathologists for online collaboration.
#6
Series A · San Francisco, California · founded 2009 · 12 employees$7Mraised▾
Provider of drug research and development services for cell & gene therapies
- Mar 2023Series A$4M
- Jul 2018Seed$3M
- Jan 2016Grant (prize money)$150K
#7
Series A · Tampa, Florida · founded 2002 · 7 employees$5Mraised▾
BioLeap is a drug design company enabled by computational fragment-based design technology. The company's in silico design platform predicts binding affinity based on thermodynamic principles giving drug designers insights to create non-obvious molecules and improve existing molecules. Addresses problems in drug discovery like the limitation of drug-like and patentable leads for important but often difficult biological targets. The company's technology provides a viable alternative to high-throughput screening and traditional shape-based “docking” approaches.
- Sep 2013Grant (prize money)$216.7K
- Jan 2010Series A$5M
#8
Funding Raised · Mountain View, California · founded 2002 · 6 employees$3.9Mraised▾
Provider of bioinformatics software and consulting for biological pathway modeling. This company offers software and expert consulting services to academic and industry laboratories. Their expertise lies in modeling complex biological systems, from molecular cell biology to human physiology. The company's software provides a user-friendly interface for quantitative testing of theories against experimental data. They support clients throughout the process, guiding them in the analysis and interpretation of their results.
- Jun 2013Grant (prize money)$976K
- Sep 2010Grant (prize money)$976K
- Jul 2008Grant (prize money)$976K
- Jul 2006Grant (prize money)$976K
#9
Seed · Laguna Niguel, California · founded 2022$599.5Kraised▾
Developer of RNAs to treat various diseases
#10
Deadpooled · Framingham, Massachusetts · founded 2010$2.4Mraised▾
OncoTree DTS develops vascular informatics software that helps into oncology research, drug discovery and translational development. Raul Brauner, Founder and CEO of Bio-Tree Systems is listed as single executive in filings. Currently it seems out of business
- Apr 2012Conventional Debt$750K
- Jan 2012Seed$2.4M
- Dec 2011Conventional Debt$2.4M
#11
Funding Raised · Portland, Oregon · founded 2016 · 6 employees$224.9Kraised▾
Provider of an AI-based bioimaging and molecular modeling tool for drug discovery. The company has developed a structure-based drug discovery tool called CryoDiscovery that uses Machine Learning (ML) technology to generate biomedical images of molecules and structures in a 3D model. It tool can generate and analyze molecule binding modes, protein targets, and more for the workflow of the drug discovery process. The tool is built for cryo-EM image processing to assists the researcher.
- Mar 2020Grant (prize money)$224.9K
#12
Funding Raised · San Jose, California · founded 2012 · 6 employees$65.3Kraised▾
H2OPTX works at the integration of Raman spectroscopy, optical and UV microscopy to provide solutions for analyzing the chemical structure of pharmaceuticals. It enables scanning and analysis of tablets and large volumes of complex powders with automated X-Y-Z surface scanning. It also offers a software solution for processing the multi-spectral data from its solution H2Optx mPAT LAB. Additionally, it offers R&D and IP development services.
- Sep 2017Grant (prize money)$65.3K
Funding & investor landscape
Notable founders
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.