/* Disease evidence graph — additions to the shared Explore shell.
   Palette and faces come from explore.css; only the explorer's own surfaces
   are defined here. Lane hues are fixed per relation and used by the graph,
   the legend, the ranked panels and the gap chart, so a colour means the same
   thing everywhere on the page. */
.dx{--risk:#a35138;--treat:#167b70;--protect:#335f91;--mech:#766092;--assoc:#64788a;
    --paper:#fff;--line:#d9e4eb;--mist:#edf3f6;--ink:#24354b;--sub:#566b7d;
    --warn:#8a5a10;font-family:var(--ex-sans);color:var(--ink)}
.dx [id]{scroll-margin-top:96px}
.dx-wrap{max-width:1180px;margin:0 auto;padding:0 20px}

/* ---------------------------------------------------------------- hero */
.dx-hero{padding:38px 0 26px;border-bottom:1px solid var(--line)}
.dx-hero h1{font:500 clamp(34px,5vw,52px)/1.06 var(--ex-display);margin:10px 0 14px;letter-spacing:-.01em}
.dx-kicker{font:600 11px/1 var(--ex-sans);letter-spacing:.14em;text-transform:uppercase;color:var(--ex-teal)}
.dx-lede{font-size:17px;line-height:1.65;color:var(--sub);max-width:70ch;margin:0 0 6px}
.dx-lede b{color:var(--ink);font-weight:600}

/* ---------------------------------------------------------------- search */
.dx-search{position:relative;margin:26px 0 0;max-width:640px}
.dx-search input{width:100%;font:400 17px var(--ex-sans);padding:15px 46px 15px 16px;
  border:1px solid #b7cbd6;border-radius:6px;background:var(--paper);color:var(--ink)}
.dx-search input:focus{outline:2px solid var(--ex-blue);outline-offset:1px;border-color:var(--ex-blue)}
.dx-search::after{content:"";position:absolute;right:16px;top:17px;width:15px;height:15px;
  border:2px solid #90a7b5;border-radius:50%;pointer-events:none}
.dx-search-note{font-size:12px;color:var(--sub);margin:8px 0 0}
.dx-sugg{position:absolute;z-index:40;left:0;right:0;top:calc(100% + 4px);background:var(--paper);
  border:1px solid var(--line);border-radius:6px;box-shadow:0 12px 30px rgba(36,53,75,.16);
  max-height:392px;overflow:auto;display:none}
.dx-sugg[data-open="1"]{display:block}
.dx-sugg button{display:flex;gap:10px;align-items:baseline;width:100%;text-align:left;background:none;
  border:0;border-bottom:1px solid var(--mist);padding:10px 14px;font:400 15px var(--ex-sans);
  color:var(--ink);cursor:pointer}
.dx-sugg button:last-child{border-bottom:0}
.dx-sugg button:hover,.dx-sugg button[aria-selected="true"]{background:var(--mist)}
.dx-sugg em{font-style:normal;font-weight:600}
.dx-sugg small{margin-left:auto;color:var(--sub);font-size:11.5px;white-space:nowrap}
.dx-chip-kind{font:600 9.5px/1 var(--ex-sans);letter-spacing:.09em;text-transform:uppercase;
  padding:3px 6px;border-radius:3px;background:var(--mist);color:var(--sub)}
.dx-chip-kind[data-k="c"]{background:#e4efe9;color:#14604f}
.dx-chip-kind[data-k="f"]{background:#e7edf5;color:#2c4f77}

/* ---------------------------------------------------------------- starts */
.dx-starts{margin:30px 0 0;display:grid;gap:18px;grid-template-columns:repeat(auto-fit,minmax(230px,1fr))}
.dx-starts h3{font:600 11px/1 var(--ex-sans);letter-spacing:.1em;text-transform:uppercase;
  color:var(--sub);margin:0 0 10px}
.dx-starts div{display:flex;flex-wrap:wrap;gap:6px}
.dx-pill{font:400 13px var(--ex-sans);padding:6px 11px;border:1px solid var(--line);border-radius:20px;
  background:var(--paper);color:var(--ink);cursor:pointer}
.dx-pill:hover{border-color:var(--ex-teal);color:var(--ex-teal)}

/* ---------------------------------------------------------------- subject */
.dx-subject{padding:30px 0 0}
.dx-trail{display:flex;flex-wrap:wrap;gap:6px;align-items:center;font-size:12.5px;color:var(--sub);min-height:22px}
.dx-trail button{font:400 12.5px var(--ex-sans);background:none;border:0;padding:2px 0;color:var(--ex-blue);
  text-decoration:underline;cursor:pointer}
.dx-trail span{color:#9bb0bd}
.dx-title{display:flex;flex-wrap:wrap;align-items:baseline;gap:12px;margin:8px 0 0}
.dx-title h2{font:500 clamp(28px,4vw,42px)/1.1 var(--ex-display);margin:0}
.dx-role{display:flex;gap:6px}
.dx-role button{font:600 10.5px var(--ex-sans);letter-spacing:.08em;text-transform:uppercase;
  padding:5px 10px;border:1px solid var(--line);background:var(--paper);border-radius:4px;
  color:var(--sub);cursor:pointer}
.dx-role button[aria-pressed="true"]{background:var(--ink);border-color:var(--ink);color:#fff}
.dx-role button:disabled{opacity:.4;cursor:not-allowed}

.dx-kpis{display:grid;grid-template-columns:repeat(auto-fit,minmax(140px,1fr));gap:1px;
  background:var(--line);border:1px solid var(--line);border-radius:6px;overflow:hidden;margin:20px 0 0}
.dx-kpis div{background:var(--paper);padding:14px 16px}
.dx-kpis b{display:block;font:500 25px/1.1 var(--ex-display);color:var(--ink)}
.dx-kpis span{display:block;font-size:11.5px;color:var(--sub);margin-top:5px;line-height:1.4}

/* ---------------------------------------------------------------- graph */
.dx-graph{margin:30px 0 0;border:1px solid var(--line);border-radius:8px;background:var(--paper);overflow:hidden}
.dx-bar{display:flex;flex-wrap:wrap;gap:14px;align-items:center;padding:12px 16px;
  border-bottom:1px solid var(--line);background:#fbfcfd}
.dx-bar>b{font:600 11px var(--ex-sans);letter-spacing:.1em;text-transform:uppercase;color:var(--sub)}
.dx-toggle{display:inline-flex;border:1px solid var(--line);border-radius:5px;overflow:hidden}
.dx-toggle button{font:400 12.5px var(--ex-sans);padding:7px 13px;border:0;background:var(--paper);
  color:var(--sub);cursor:pointer}
.dx-toggle button+button{border-left:1px solid var(--line)}
.dx-toggle button[aria-pressed="true"]{background:var(--ex-teal);color:#fff}
.dx-lanes{display:flex;flex-wrap:wrap;gap:5px;margin-left:auto}
.dx-lanes button{font:400 12px var(--ex-sans);padding:5px 10px;border:1px solid var(--line);
  border-radius:16px;background:var(--paper);cursor:pointer;color:var(--sub);display:flex;align-items:center;gap:6px}
.dx-lanes button::before{content:"";width:9px;height:9px;border-radius:50%;background:currentColor}
.dx-lanes button[aria-pressed="true"]{border-color:currentColor;font-weight:600}
.dx-lanes button[aria-pressed="false"]{opacity:.45}
.dx-lane-risk{color:var(--risk)}.dx-lane-treat{color:var(--treat)}.dx-lane-protect{color:var(--protect)}
.dx-lane-mech{color:var(--mech)}.dx-lane-assoc{color:var(--assoc)}

.dx-canvas{position:relative;display:grid;grid-template-columns:minmax(0,1fr) 244px}
.dx-canvas svg{width:100%;height:auto;display:block;touch-action:manipulation}
.dx-node{cursor:pointer}
.dx-node circle{transition:stroke-width .12s}
/* Sizes are viewBox user units, not CSS pixels: the graph scales down to fit
   its column, so 16 here renders at roughly 12. */
.dx-node text{font:400 16px var(--ex-sans);fill:var(--ink);pointer-events:none}
.dx-node:hover circle,.dx-node:focus circle{stroke:var(--ink);stroke-width:2.5}
.dx-node:focus{outline:none}
.dx-node:focus text{text-decoration:underline}
/* the attribute fill on hub text loses to the .dx-node rule, so set it here */
.dx-hub text{font-family:var(--ex-display);font-weight:500;fill:#fff}
.dx-hub circle{stroke:#fff;stroke-width:3}
.dx-edge{fill:none;stroke-linecap:round}
.dx-lanelab{font:600 13px var(--ex-sans);letter-spacing:.1em;text-transform:uppercase}
.dx-aside{border-left:1px solid var(--line);padding:16px;background:#fbfcfd;font-size:13px;min-width:0}
.dx-aside h4{font:500 19px/1.2 var(--ex-display);margin:0 0 3px}
.dx-aside .dx-aside-rel{font:600 10px var(--ex-sans);letter-spacing:.09em;text-transform:uppercase;margin:0 0 12px}
.dx-aside dl{display:grid;grid-template-columns:1fr auto;gap:7px 10px;margin:0 0 14px;font-size:12.5px}
.dx-aside dt{color:var(--sub)}
.dx-aside dd{margin:0;font-weight:600;font-variant-numeric:tabular-nums}
.dx-aside p{color:var(--sub);line-height:1.6;font-size:12.5px;margin:0 0 12px}
.dx-aside button{font:400 13px var(--ex-sans);width:100%;padding:9px;border:1px solid var(--ex-teal);
  background:var(--ex-teal);color:#fff;border-radius:5px;cursor:pointer}
.dx-aside button:disabled{background:var(--mist);border-color:var(--line);color:var(--sub);cursor:default}
.dx-empty-aside{color:var(--sub);line-height:1.65}
.dx-foot{padding:10px 16px;border-top:1px solid var(--line);font-size:11.5px;color:var(--sub);background:#fbfcfd}

/* ---------------------------------------------------------------- sections */
.dx-sec{margin:44px 0 0}
.dx-sec>h3{font:500 27px/1.2 var(--ex-display);margin:0 0 6px}
.dx-sec>p.dx-intro{color:var(--sub);font-size:14px;line-height:1.65;max-width:78ch;margin:0 0 18px}
.dx-grid{display:grid;gap:18px;grid-template-columns:repeat(auto-fit,minmax(300px,1fr))}
.dx-card{border:1px solid var(--line);border-radius:7px;background:var(--paper);overflow:hidden}
.dx-card>header{padding:12px 15px;border-bottom:1px solid var(--line);display:flex;align-items:baseline;gap:8px}
.dx-card>header b{font:600 12px var(--ex-sans);letter-spacing:.06em;text-transform:uppercase}
.dx-card>header small{margin-left:auto;color:var(--sub);font-size:11.5px}
.dx-card ol{list-style:none;margin:0;padding:6px 0}
.dx-card li{display:grid;grid-template-columns:1fr auto;align-items:center;gap:10px;padding:7px 15px}
.dx-card li:hover{background:var(--mist)}
.dx-card li button{font:400 14px var(--ex-sans);background:none;border:0;padding:0;text-align:left;
  color:var(--ink);cursor:pointer;text-decoration:underline;text-decoration-color:#c3d3dd}
.dx-card li button:hover{color:var(--ex-teal)}
.dx-card li i{font-style:normal;font-size:12px;color:var(--sub);font-variant-numeric:tabular-nums;white-space:nowrap}
.dx-meter{grid-column:1/-1;height:3px;background:var(--mist);border-radius:2px;overflow:hidden}
.dx-meter span{display:block;height:100%}
.dx-thin{padding:12px 15px;font-size:12.5px;color:var(--warn);background:#fdf8ef;border-top:1px solid #f0e3cb}

/* gap chart */
.dx-gap{border:1px solid var(--line);border-radius:7px;background:var(--paper);padding:4px 0}
.dx-gap table{width:100%;border-collapse:collapse;font-size:13.5px}
.dx-gap th{font:600 10.5px var(--ex-sans);letter-spacing:.08em;text-transform:uppercase;color:var(--sub);
  text-align:right;padding:10px 15px;border-bottom:1px solid var(--line)}
.dx-gap th:first-child{text-align:left}
.dx-gap td{padding:8px 15px;border-bottom:1px solid var(--mist);vertical-align:middle}
.dx-gap tr:last-child td{border-bottom:0}
.dx-gap td:not(:first-child){text-align:right;font-variant-numeric:tabular-nums}
.dx-gap button{font:400 13.5px var(--ex-sans);background:none;border:0;padding:0;color:var(--ink);
  cursor:pointer;text-decoration:underline;text-decoration-color:#c3d3dd;text-align:left}
.dx-gap button:hover{color:var(--ex-teal)}
.dx-ratio{display:inline-block;padding:2px 7px;border-radius:3px;font-size:11.5px;font-weight:600}
.dx-ratio[data-w="1"]{background:#fbeee0;color:#8a5a10}
.dx-ratio[data-w="0"]{background:var(--mist);color:var(--sub)}

/* tier + trend */
.dx-tier{display:flex;height:34px;border-radius:5px;overflow:hidden;border:1px solid var(--line)}
.dx-tier span{display:flex;align-items:center;justify-content:center;font-size:11px;color:#fff;
  min-width:0;overflow:hidden;white-space:nowrap}
.dx-tierkey{display:flex;flex-wrap:wrap;gap:14px;margin:12px 0 0;font-size:12px;color:var(--sub)}
.dx-tierkey b{display:inline-block;width:9px;height:9px;border-radius:2px;margin-right:6px}
.dx-trend{border:1px solid var(--line);border-radius:7px;background:var(--paper);padding:16px}
.dx-trend svg{width:100%;height:auto;display:block}
.dx-trend text{font:400 12px var(--ex-sans);fill:var(--sub)}

/* method */
.dx-method{margin:48px 0 0;border-top:1px solid var(--line);padding:26px 0 0}
.dx-method h3{font:500 23px var(--ex-display);margin:0 0 12px}
.dx-method dl{margin:0;display:grid;gap:16px;grid-template-columns:repeat(auto-fit,minmax(270px,1fr))}
.dx-method dt{font-weight:600;font-size:13.5px;margin:0 0 5px}
.dx-method dd{margin:0;font-size:13px;line-height:1.7;color:var(--sub)}
.dx-hide{display:none}

@media (max-width:860px){
  .dx-canvas{grid-template-columns:1fr}
  .dx-aside{border-left:0;border-top:1px solid var(--line)}
  .dx-lanes{margin-left:0;width:100%}
}
@media (prefers-reduced-motion:reduce){.dx *{transition:none!important}}