Best Artificial Intelligence Companies in Cambridge, United States
The 82 best Artificial Intelligence companies in Cambridge, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: XtalPi.
Our analysis of 101 Artificial Intelligence companies
$80.5b in tracked funding; 99% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Artificial Intelligence companies in Cambridge
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | XtalPi 🦄 AI-based drug research and development company 64Funding top 18%AI top 26%Talent top 28%Patents top 31% All 13 signals ▾Fundingtop 18% AItop 26% Talenttop 28% Patentstop 31% Moattop 31% Innovationtop 34% Producttop 35% Newstop 38% Techtop 39% Growthtop 47% Globaltop 50% Marketbottom 43% Fin. healthbottom 32% Funding: Raised $785M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) AI: Classified as an AI company · Product described with: ai-based, machine learning rank vs industry peers · Fliar Intelligence Index 64/100 | $785M | 9 mo ago | 27 | — | WordPressMySQLPHP+28 | Top 5M | 14 patents Immuno‑oncology therapeutics: STING pathway modulators and PI3Kβ inhibitor drug candidates | 1 partnership |
| 2 | Relay Therapeutics Developer of drug discovery platform and study protein motion | $520M | 29 mo ago | 245 245 → 218 (-11%) · sector median +42% | David Shaw Co-Founder | WordPressDrupalApple iCloud Mail+23 | Top 10M | 234 patents Small-molecule FGFR and PI3Kα kinase inhibitors for oncology applications | — |
| 3 | In Silico AI-enabled bioinformatics platform for drug discovery and biomarker development 82Funding top 15%Product top 19%AI top 20%News top 26% All 12 signals ▾Fundingtop 15% Producttop 19% AItop 20% Newstop 26% Partnerstop 26% Talenttop 28% Moattop 31% Innovationtop 35% Growthtop 35% Markettop 43% Techtop 46% Globalbottom 39% Funding: Raised $400M across 11 rounds · 11 rounds over 12 yrs (0.9/yr) Product: 3 distinct product lines · Company stage: Public rank vs industry peers · Fliar Intelligence Index 82/100 | $400M | 17 mo ago | 300 | Alex Zhavoronkov Co-Founder & Co-CEO | SentryMUIReact+10 | Top 5M | — | — |
| 4 | Cellarity AI-powered drug design and development platform | $294M | 44 mo ago | 117 117 → 72 (-38%) · sector median +42% | — | — | — | 26 patents AI-driven drug discovery and cellular diagnostic platforms using heterocyclic modulators | — |
| 5 | Suno 🦄 Provider of music creation platform enabling users to easily create and share original songs 93Customers top 5%Funding top 19%Growth top 22%Tech top 24% All 10 signals ▾Customerstop 5% Fundingtop 19% Growthtop 22% Techtop 24% Moattop 26% Talenttop 28% AItop 30% Markettop 34% Producttop 40% Globalbottom 32% Customers: Play-Store rating 4.84★ across 1,750,077 ratings (1 apps) Funding: Raised $125M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 93/100 | $125M | 7 mo ago | — | Georg Kucsko Co-Founder & CTO | TurbopackEmotionSentry+39 | Top 5k | — | 2 launchs · 1 award |
| 6 | Kensho Provider of AI-based software solutions for law enforcement and businesses | $123M | 111 mo ago | 98 98 → 189 (+93%) · sector median +42% | — | SentryApple iCloud MailGoogle Workspace+24 | Top 5M | 7 patents Financial data mining and analytics platforms for predictive modeling and domain-specific search | 2 launchs · 2 partnerships · 1 award |
| 7 | Dyno Therapeutics Provider of Ai-based data-driven adeno-associated virus (AAV) engineering | $109M | 61 mo ago | 38 38 → 91 (+139%) · sector median +42% | — | WebflowZohoGSAP+10 | Top 5M | — | 1 partnership |
| 8 | Pickle Robot Developer of AI-powered robotic systems for warehouse and supply chain automation | $95M | 26 mo ago | 18 | Dan Paluska Co-Founder | WordPressMySQLPHP+21 | Top 10M | — | 1 job opening · 2 launchs · 1 award |
| 9 | iSee Developer of autonomous driving systems for yard truck applications | $70M | 43 mo ago | 72 72 → 70 (-3%) · sector median +42% | Debbie Yu Co-Founder & Board Member | Craft CMSPHPYii+16 | Top 10M | 40 patents Automated truck coupling, robotic arm safety, and vision-based motion planning systems | — |
| 10 | Tamr Provider of AI-native master data management platform for data unification | $69M | 35 mo ago | 121 121 → 117 (-3%) · sector median +42% | Daniel Bruckner Co-Founder & CTO | WebflowSentryAtlassian Statuspage+25 | Top 5M | 37 patents Enterprise data integration: automated entity resolution, record clustering, and hierarchical classification. | — |
| 11 | nference Provider of an AI platform for clinical data analysis and insights | $63M | 44 mo ago | 165 165 → 316 (+92%) · sector median +42% | Murali Aravamudan Co-Founder & CEO | PrismicNode.jsMUI+19 | Top 5M | 126 patents Patents concentrated in computing, sensing & instrumentation | — |
| 12 | Marqvision Provider of counterfeiting solutions for e-commerce businesses | $46M | 9 mo ago | 100 | — | WebflowSentryZendesk+21 | Top 5M | — | 1 partnership |
| 13 | Goldcast Cloud based platform offering virtual event management solutions | $42M | 45 mo ago | 47 | Aashish Srinivas Co-Founder & CTO | SentryZendeskNode.js+31 | Top 5M | — | — |
| 14 | RapidMiner Provider of data science platform on open stack | $36M | 79 mo ago | 17 | — | Atlassian Jira Issue CollectorAlgoliaSalesforce+29 | Top 1M | — | — |
| 15 | Modulate Provider of voice AI for fraud detection and online safety solutions | $32M | 46 mo ago | 30 30 → 56 (+87%) · sector median +42% | Carter Huffman Co-Founder & CTO | WebflowGSAPTypekit+22 | Top 5M | 35 patents Audio signal processing for timbre synthesis and voice chat moderation systems | 1 launch |
| 16 | Alife Health AI-based fertility care solutions for clinicians | $32M | 51 mo ago | 23 | Paxton York Founder | ContentfulTailwind CSSstyled-components+20 | Top 5M | — | 1 partnership |
| 17 | Cleanlab AI Provider of a platform offering data cleansing solutions | $30M | 32 mo ago | 20 | Anish Athalye Co-Founder | Node.jsRadix UIReact+19 | Top 10M | — | — |
| 18 | Robust Intelligence Robust Intelligence provides a platform that automates end-to-end security of artificial intelligence (AI)… | $30M | 54 mo ago | 30 | Yaron Singer CEO | WebflowThree.jsSwiper+13 | Top 5M | 19 patents Adversarial robustness and security for AI models and container images | — |
| 19 | 1910 Genetics Developer of small molecule therapeutics to treat pain and aging-related diseases | $30M | 19 mo ago | 18 | Jen Nwankwo Founder & CEO | — | — | — | — |
| 20 | Vlingo Voice enabled virtual assistant | $26M | 201 mo ago | 30 | — | — | — | 10 patents Voice-driven text entry and control for mobile communication devices | — |
| 21 | Kebotix AI solutions for materials discovery | $24M | 23 mo ago | 12 | Jill Becker CEO | — | — | 24 patents AI-driven molecular property prediction and automated synthesis for functional organic materials | — |
| 22 | Rgo Robotics Developer of AI-powered perception software for mobile robotic platforms | $20M | 49 mo ago | 58 | Nizan Horesh Co-Founder & CTO | WixSentryBootstrap+15 | Top 50M | — | — |
| 23 | Axiomatic AI Developer of verifiable AI for scientific and engineering applications 60Talent top 23%AI top 30%Funding top 34%Growth top 35% All 7 signals ▾Talenttop 23% AItop 30% Fundingtop 34% Growthtop 35% Globalbottom 48% Techbottom 42% Marketbottom 35% Talent: 6 named leaders on record · 6 C-suite/founder profiles curated AI: Classified as an AI company · Product described with: deep learning rank vs industry peers · Fliar Intelligence Index 60/100 | $18M | 3 mo ago | — | Alan Aspuru-Guzik Co-Founder
| JavaAstroCloudflare+6 | Top 10M | — | 2 launchs |
| 24 | Akkio AI Provider of solutions to build AI applications without coding | $18M | 34 mo ago | 15 | Abraham Parangi Co-Founder & CEO | WebflowApple iCloud MailGoogle Workspace+27 | Top 1M | 9 patents Patents concentrated in computing, sensing & instrumentation | 1 partnership |
| 25 | Hosta AI-driven property assessment solution for property owners & managers | $15M | 55 mo ago | 30 | Henriette Fleischmann Co-Founder & COO | WordPressMySQLPHP+19 | Top 10M | — | 1 job opening |
| 26 | Netpreme Developer of memory to compute networking solutions for AI infrastructure systems | $12M | 11 mo ago | — | Zhizhen Zhong Founder & CEO | TurbopackNode.jsRadix UI+12 | Top 50M | — | 1 job opening · 1 launch |
| 27 | Leo AI AI platform specifically for mechanical engineers and engineering firms | $10M | 9 mo ago | — | Maor Farid Co-Founder & CEO | Framer SitesYouTubeReact+15 | Top 5M | — | — |
| 28 | Origin Medical AI powered platform to support prenatal care with an evaluation of pregnancy | $7M | 10 mo ago | — | Sripad Devalla Co-Founder & CEO | WebflowMicrosoft ClarityGoogle Analytics+14 | Top 10M | — | — |
| 29 | Fritz AI tools and platform simplifying machine learning for developers | $7M | 75 mo ago | 5 | — | WordPress Block EditorWordPressMySQL+20 | Top 5M | — | — |
| 30 | Einblick AI-native collaborative data science platform | $6M | 66 mo ago | 21 | Ali Ghodsi CEO | — | — | — | — |
| 31 | Salient Predictions Offering AI based solutions for weather forecasting | $6M | 15 mo ago | 2 | Ray Schmitt President & Co-founder | Webflowcore-jsjQuery+12 | Top 50M | 2 patents Neural-network ensemble blending for probabilistic weather forecasting | — |
| 32 | Vistapath AI and cloud-based pathology processing platform for diagnosis | $5M | 35 mo ago | 6 | Ben Burley Co-Founder | — | — | — | — |
| 33 | Blitzy 🦄 AI powered IT application development platform 74Tech top 30%AI top 30%Moat top 31%Growth top 35% All 9 signals ▾Techtop 30% AItop 30% Moattop 31% Growthtop 35% Fundingtop 36% Talenttop 38% Markettop 50% Globalbottom 38% Newsbottom 18% Tech: 37 technologies across 5/8 capability areas · Cloud: Amazon S3, Amazon Web Services AI: Classified as an AI company · Product described with: ai powered rank vs industry peers · Fliar Intelligence Index 74/100 | $4M | 1 mo ago | — | Sid Pardeshi Co-Founder & CTO | FirebaseRadix UITailwind CSS+22 | Top 5M | — | 7 job openings |
| 34 | Memorable Provider of branding, and artificial intelligence services | $3M | 43 mo ago | 23 | — | — | — | — | — |
| 35 | Basys.ai Provider of SaaS-based platform for clinical decision-making for doctors at hospitals | $2M | 35 mo ago | 8 | Amber Nigam Co-founder and CEO | Webflow EcommerceWebflowjQuery+6 | Top 50M | 2 patents Enterprise identity‑access management platform for authorization request handling | 1 partnership |
| 36 | Energid Developer of advanced motion control software integrated with robot controllers | $500K | 137 mo ago | 24 | — | — | — | — | — |
| 37 | OtoSense Provider of an ML-based sound recognition solution for industrial predictive maintenance | $370K | 136 mo ago | 4,814 | — | — | — | 12 patents AI-driven acoustic event detection and real-time neuro-compatible signal imaging | — |
| 38 | StackAI Developer of software for building and deploying automated artificial agents | $125K | 20 mo ago | 2 | Bernardo Aceituno Co-Founder & President | Framer SitesReactstyled-components+7 | Top 5M | — | — |
| 39 | Granular AI-powered geospatial intelligence for informed decisions with global reach | $100K | 62 mo ago | 14 | Siddharth Gupta Founder & CEO | Node.jsHeadless UITailwind CSS+13 | Top 50M | — | — |
Top 12 Artificial Intelligence companies in Cambridge
#1
XtalPi 🦄Public · Cambridge, Massachusetts · founded 2014 · 27 employees$784.8Mraised▾
XtalPi has developed a proprietary technology FACES(Fast Accurate Crystalline Engineering System), which is a cloud-based computing system to predict the crystal structure which will identify polymorphs of the compound. The company's algorithms are integrated with the Amazon Web Service (AWS) high-performance computing (HPC) resources in the cloud. The team claims to have a strong background in quantum physics and machine learning. It provides services to pharmaceutical companies at various stages of drug development. The company has deployed its technology to develop an Intelligent Digital Drug Discovery and Development (ID4) platform to improve the efficiency, accuracy, and success rate of drug discovery.
- Sep 2025Post IPO$268M
- Feb 2025Post IPO$268.4M
- Aug 2021Series D$400M
- Sep 2020Series C$318.8M
#2
Suno 🦄Series C · Cambridge, Massachusetts · founded 2021$125Mraised▾
Provider of music creation platform enabling users to easily create and share original songs. It provides users with a music studio that enables users to create and share music through its intuitive platform, leveraging artificial intelligence to generate realistic songs. The company's mission is to democratize music creation and bridge the gap between artists and their compositions. By providing a user-friendly interface and accessible tools, Suno aims to empower individuals to produce high-quality music.
- Nov 2025Series C$250M
- May 2024Series B$125M
#3
Seed · Cambridge, Massachusetts · founded 2024$18Mraised▾
Developer of verifiable AI for scientific and engineering applications. It integrates formal verification with deep learning to generate interpretable, consistent, and logically verifiable results. This approach reduces hallucinations and ensures mathematically verifiable, error-free outputs. It accelerates the creation of physics-based models, enabling accurate data extraction from technical documentation and optimization using experimental data. The AI capabilities accelerate photonic and semiconductor design, minimizing errors and speeding up development.
- Mar 2026Seed$18M
#4
Public · Cambridge, Massachusetts · founded 2014 · 300 employees$399.8Mraised▾
AI-enabled bioinformatics platform for drug discovery and biomarker development. The company provides solutions and services such as custom drug discovery engines, biomarker discovery, and aging research tools to academia, pharmaceutical, and cosmetics companies. Also, it has developed a product PHARMA.AI which includes modules for drug discovery such as PandaOmics, Chemistry42, and InClinico.
- Jan 2025Series E$110M
- Aug 2022Series D$35M
- Jun 2022Series D$60M
- Jun 2021Series C$255M
#5
Series B · Cambridge, Massachusetts · founded 2019 · 100 employees$46.3Mraised▾
Provider of counterfeiting solutions for e-commerce businesses. The company offers a brand protection platform that allows companies to automatically detect and remove counterfeits products sold online. It uses machine learning technology to detects infringements in listings based on information such as price, product description, and customer reviews, enabling brands to protect sales and reputation from IP infringement.
- Sep 2025Series B$48M
- Oct 2024Series A$16M
- Aug 2022Series A$25.3M
- Sep 2021Seed$5M
#6
Blitzy 🦄Series B · Cambridge, Massachusetts · founded 2023$4.4Mraised▾
AI powered IT application development platform. Its AI tool automates the custom software development process. The platform automates the software development lifecycle, allowing for creation and deployment of applications. It allows users to specify the app requirements in natural language, and the AI generates the app based on user specification.
- May 2026Series B$200M
- Sep 2024Series A$4.4M
#7
Seed · Cambridge, Massachusetts · founded 2023$9.7Mraised▾
AI platform specifically for mechanical engineers and engineering firms. It allow engineers to assist with technical queries, design concept generation, part selection, and CAD-related workflows using advanced AI models. The platform leverages artificial intelligence to streamline the design process, providing technical answers and access to library of resources.
- Sep 2025Seed$9.7M
#8
Series B · Cambridge, Massachusetts · founded 2024$11.7Mraised▾
Developer of memory to compute networking solutions for AI infrastructure systems. The company focuses on high-bandwidth optical interconnects for XPU memory expansion. It contributes to the development of memory-to-compute fabric.
- Jun 2025Series B$11.7M
#9
Series A · Cambridge, Massachusetts · founded 2019$7.2Mraised▾
AI powered platform to support prenatal care with an evaluation of pregnancy. It offers exam assistant platform is built on AI that equips maternal health practitioners with real time assistance in acquiring diagnostic imaging and interpreting prenatal ultrasound examinations at every stage of pregnancy.
- Jul 2025Series A$550K
- May 2023Series A$6.7M
#10
Public · Cambridge, Massachusetts · founded 2016 · 245 employees$520Mraised▾
Relay Therapeutics is a developer of a drug discovery platform and study protein motion. The company’s drug discovery engine provides 3D visuals on the mobility of a protein to study or analyze the function of protein-based on its motion. It also enables the researchers to study the ligand-binding pockets present in the protein and detect ligand-protein binding interactions. The company’s initial program focuses on developing therapeutics in oncology.
- Jan 2024Post IPO$30M
- Dec 2018Series C$400M
- Dec 2017Series B$63M
- Sep 2016Series A$57M
#11
Series A · Cambridge, Massachusetts · founded 2018 · 18 employees$29.8Mraised▾
Developer of small molecule therapeutics to treat pain and aging-related diseases. It is a biotechnology company that integrates AI, computation, and biological automation to accelerate the design of small molecule and protein therapeutics. The company have developed two discovery engines ELVIS and ROSALYND that enable to design drug candidates.
- Oct 2024Series A—
- Sep 2021Grant (prize money)$550K
- Jul 2021Grant (prize money)$546.4K
- Mar 2021Series A$25.7M
#12
Series B · Cambridge, Massachusetts · founded 2017 · 12 employees$23.7Mraised▾
AI solutions for materials discovery. Its technology integrates cloud technologies, artificial intelligence, chemical informatics, physical modeling, and lab automation to support the R&D process. It accelerate the discovery, testing, and production processes of new molecules.
- Jul 2024Series B$5M
- Apr 2023Series A$2.2M
- Dec 2021Grant (prize money)—
- Mar 2021Series A—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Artificial Intelligence coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Artificial Intelligence in Cambridge is moving
A read on the academic research around Artificial Intelligence in Cambridge — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 67 papers.
- University of Cambridge56
- Cambridge University Hospitals NHS Foundation Trust6
- Cancer Research UK Cambridge Center2
- Cambridge Collaborative2
- Cambridge Crystallographic Data Centre1
- Segmentation6
- Set (abstract data type)4
- Convolutional neural network3
- Artificial neural network3
- Inference3
- Support vector machine1
- Artificial neural network1
- Cross-validation1
- Sensitivity (control systems)1
- Data mining1
- Resilience (materials science)2
- Cluster analysis1
- Somatic cell1
- Selection (genetic algorithm)1
- Genetics1