Best Artificial Intelligence Companies in Maryland, United States
The 49 best Artificial Intelligence companies in Maryland, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: BrainScope.
Our analysis of 101 Artificial Intelligence companies
$80.5b in tracked funding; 99% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Artificial Intelligence companies in Maryland
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | BrainScope Provider of AI-powered non-invasive medical devices for diagnosing and assessing brain injuries, including… | $62M | 34 mo ago | Series B | Michael Singer Co-CEO | 2006 | HubSpot CMS HubEnvoyBootstrap+15 | 165 patents Patents concentrated in health & consumer products | 1 job opening |
| 2 | Origin Wireless AI Developer of motion sensors | $42M | 33 mo ago | Acquired | Ray Liu Founder | 2019 | WordPress Block EditorWordPressMySQL+28 | 170 patents Radio-frequency sensing for health monitoring, motion classification, and event detection | 4 job openings · 1 launch · 1 award |
| 3 | Ultralytics Provider of a machine learning training and deployment platform | $30M | 10 mo ago | Series A | Glenn Jocher Founder & CEO | 2014 | TurbopackNode.jsClerk+21 | — | 8 launchs |
| 4 | Incremental AI-based predictive analytics solutions for e-commerce brands | $19M | 66 mo ago | Series A | Haley Ulloa Co-Founder | Board Director | 2019 | — | — | — |
| 5 | Edgybees Provider of AR and AI based real-time geo-tagging solution | $15M | 65 mo ago | Series A | Menashe Haskin Co-Founder | 2017 | WordPressMySQLPHP+26 | — | — |
| 6 | Clean.io Proactive real-time anti-malvertising Solution | $8M | 72 mo ago | Acquired | Jay Crystal Co-Founder | 2017 | — | 13 patents Patents concentrated in computing, sensing & instrumentation | — |
| 7 | Global PayEX Provider of AI-powered AP and AR automation software | $3M | 87 mo ago | Seed | Mohan Krishnan Founder | 2011 | WordPressMySQLPHP+12 | — | — |
| 8 | OmniSpeech AI-powered voice technology enhancing speech clarity and detecting audio deepfakes | $3M | 8 mo ago | Seed | — | 2009 | — | 14 patents Advanced pitch detection algorithms for speech signal processing using PWVT and Teager energy | — |
| 9 | RedShred NLP powered document search platform | $2M | 93 mo ago | Funding Raised | — | 2012 | — | 10 patents Geospatial document management and automated structured-data analysis software | — |
| 10 | HoloMD AI-powered platform focused on psychiatric care and remote therapeutic monitoring | $2M | 8 mo ago | Seed | Ali Allage Co-Founder & Chief Technology Officer | 2024 | — | — | — |
| 11 | PlenaryAI AI-based molecular imaging tool for clinical assessment | $1M | 65 mo ago | Seed | Edward Herskovits Co-Founder & CEO & CSO | 2021 | — | — | — |
| 12 | Dentuit Provider of an AI-based remote dental diagnosis platform for professionals | $450K | 73 mo ago | Funding Raised | Dan Lee Co-Founder & CEO | 2013 | — | — | — |
Top 12 Artificial Intelligence companies in Maryland
#1
Series A · Frederick, Maryland · founded 2014 · 11 employees$30Mraised▾
Provider of a machine learning training and deployment platform. It is a global leader in vision AI, known for its pioneering YOLO models. With over hundred and fifteen GitHub stars, more than hundred million downloads, and five million monthly visitors, it delivers state-of-the-art computer vision solutions. Its advanced technology supports diverse industries including manufacturing, healthcare, transportation, agriculture, and retail by providing fast, accurate, and accessible AI tools.
- Sep 2025Series A$30M
- 2024Seed—
#2
Seed · College Park, Maryland · founded 2009 · 12 employees$3.4Mraised▾
AI-powered voice technology enhancing speech clarity and detecting audio deepfakes. The company specializes in AI/ML algorithms to improve speech performance across various applications and devices. Their technology offers AI Noise Suppression for crystal-clear voice communication by removing background noise in real-time, suitable for VoIP calls, video conferencing, and gaming. They also provide AI Audio Deepfake Detection, identifying AI-generated voices to combat voice fraud and misinformation. Additionally, their AI Speech Biomarker Identification technology unlocks health and security insights from voice data, enabling non-invasive diagnostics and biometric authentication. The solutions are designed for seamless integration with DSPs, SoCs, and operating systems, offering low latency and low power consumption, ideal for wireless headsets and battery-powered devices. The company's focus is on delivering superior performance in speech extraction and deepfake detection through proprietary training and algorithm design.
- Nov 2025Seed$500K
- Dec 2014Grant (prize money)$225K
- 2014Grant (prize money)$135K
- Aug 2013Grant (prize money)$1.1M
#3
Seed · Rockville, Maryland · founded 2024$1.6Mraised▾
AI-powered platform focused on psychiatric care and remote therapeutic monitoring. It combines clinical psychiatry expertise with AI to support clinicians through an empathetic AI agent. This agent conducts patient check-ins between visits, tracks mood, medication adherence, and treatment responses, while alerting staff to issues like deterioration.
- Nov 2025Seed$1.6M
#4
Series B · Bethesda, Maryland · founded 2006 · 38 employees$62.2Mraised▾
Provider of AI-powered non-invasive medical devices for diagnosing and assessing brain injuries, including concussions and brain bleeds.
- Sep 2023Series B—
- Oct 2021Series B—
- Aug 2017Series B$16.4M
- Sep 2015Series B$2.5M
#5
Acquired · Greenbelt, Maryland · founded 2019 · 38 employees$42.5Mraised▾
Origin Wireless is a developer of motion sensors. It uses Wi-Fi networks that detect activity inside the home without using cameras. The company claims a 99.9% detection rate and accuracy without disruptive false triggers. It also offers health care and tracking devices.
- Oct 2023Series B$15.9M
- Feb 2021Series B$14M
- Nov 2020Series B$2M
- Mar 2020Series B—
#6
Seed · Towson, Maryland · founded 2022$85Kraised▾
Open-access website for researchers to publish, review, and comment on scientific research. It allows researchers to create interactive video presentations. It increases recognition in the science sector through short video-casts.
- Mar 2025Grant (prize money)$100K
- Nov 2024Grant (prize money)$100K
- Oct 2023Seed$85K
#7
Series A · Baltimore, Maryland · founded 2019 · 23 employees$18.8Mraised▾
AI-based predictive analytics solutions for e-commerce brands. Its solutions include retail media measurement, analytics, portfolio management, and more. It helps brands measure the impact of retail media investments, optimize marketing spend, and achieve growth.
- Jan 2021Series A$15.5M
- Nov 2020Seed$3.3M
#8
Series A · Gaithersburg, Maryland · founded 2017 · 45 employees$15Mraised▾
Provider of AR and AI-based real-time geotagging solutions. The AI-based solution uses geographical positioning imagery, combined with machine learning algorithms and computer vision, to deliver visually augmented video with critical information and tagging. It provides tagging on live video feeds for application in defense, infrastructure, public safety during emergency situations
- Feb 2021Series A$9.5M
- Feb 2018Seed$5.5M
#9
Acquired · Baltimore, Maryland · founded 2017 · 28 employees$7.5Mraised▾
Clean.io offers a proactive real-time anti-malvertising solution for protecting publishers and platforms. It prevents malicious advertising in real-time on real-time traffic. Its features include page-level protection, customizable dashboards, source tracking, cross-screen protection, revenue impact, monetization KPIs, and out-of-the-box reporting.
- Aug 2020Series A$5M
- May 2019Seed$2.5M
#10
Seed · Rockville, Maryland · founded 2011 · 850 employees$3.4Mraised▾
Provider of AI-powered AP and AR automation software. This software automates accounts payable and accounts receivable processes, improving cash flow and working capital efficiency. The platform facilitates buyer-seller collaboration through digital invoice presentment and payment options, automated reconciliation, and embedded finance functionalities. It integrates with various ERP systems, streamlining accounting and data entry. The solution offers intelligent cash management tools, automated dunning, and dispute resolution capabilities.
- Apr 2019Seed$1M
- Sep 2017Seed$2.2M
- Mar 2016Seed$166.3K
#11
Funding Raised · Baltimore, Maryland · founded 2012 · 14 employees$2.1Mraised▾
NLP powered document search platform. The platform automatically searches, analyzes and extracts decision-making criteria from publicly available RFPs and grants each day. It enables users to convert unstructured data into queryable database formats, enabling organizations to extract insights from the document repositories.
- Oct 2018Grant (prize money)$745K
- Apr 2018Grant (prize money)$893.5K
- 2016Grant (prize money)$225K
- Jan 2016Grant (prize money)$247.5K
#12
Seed · Gaithersburg, Maryland · founded 2021$1Mraised▾
AI-based molecular imaging tool for clinical assessment. The company has developed a real-time, AI-assisted quantitative assessment tool for molecular images that can identify, segment, and classify tissue types. The company's tool is used for cancer classification on positron emission tomography (PET), and machine learning for Parkinson's disease subtype selection.
- Feb 2021Seed$1M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Artificial Intelligence coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Artificial Intelligence in Maryland is moving
A read on the academic research around Artificial Intelligence in Maryland — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 53 papers.
- University of Maryland, College Park39
- University of Maryland, Baltimore11
- University of Maryland, Baltimore County4
- University of Maryland Medical Center1
- University of Maryland Center for Environmental Science1
- Pattern recognition (psychology)5
- Convolutional neural network5
- Scalability3
- Artificial neural network3
- Pooling3
- Remote sensing2
- Inference2
- Field (mathematics)2
- Oyster1
- Hatchery1
- Affordance1
- Conceptualization1
- Terminology1
- Scholarship1
- Empirical research1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.