Best Artificial Intelligence Companies in Massachusetts, United States
The 256 best Artificial Intelligence companies in Massachusetts, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Snyk.
Our analysis of 101 Artificial Intelligence companies
$80.5b in tracked funding; 99% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Artificial Intelligence companies in Massachusetts
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Snyk 🦄 Provider of a platform securing code, models, and agents in applications | $1.3B | 26 mo ago | Series G | 1,138 | Assaf Hefetz Co-Founder & CTO | SentryApple iCloud MailGoogle Workspace+30 | — | — |
| 2 | DataRobot 🦄 Provider of an agent workforce platform for enterprise artificial intelligence | $1.1B | 59 mo ago | Series G | 453 | Debanjan Saha Chief Executive Officer | WordPressApple iCloud MailAlgolia+39 | 132 patents Automated machine learning: feature engineering, model selection, performance visualization, time‑series, generative AI evaluation | — |
| 3 | Lightmatter 🦄 Developer of photonic interconnects and co-packaged optics for AI infrastructure 87Patents top 10%Funding top 17%Innovation top 18%AI top 18% All 11 signals ▾Patentstop 10% Fundingtop 17% Innovationtop 18% AItop 18% Moattop 22% Talenttop 28% Markettop 40% Techtop 40% Growthtop 43% Globalbottom 42% Newsbottom 21% Patents: 393 patents matched (strict assignee match) · 297 filings since 2022 vs 96 in 2017-21 Funding: Raised $850M across 8 rounds · 8 rounds over 9 yrs (0.9/yr) rank vs industry peers · Fliar Intelligence Index 87/100 | $850M | 20 mo ago | Series D | 137 | Darius Bunandar Co-Founder | WordPressApple iCloud MailGoogle Workspace+19 | 393 patents Patents concentrated in computing, sensing & instrumentation | 1 internship · 1 partnership · 1 award |
| 4 | XtalPi 🦄 AI-based drug research and development company 64Funding top 18%AI top 26%Talent top 28%Patents top 31% All 13 signals ▾Fundingtop 18% AItop 26% Talenttop 28% Patentstop 31% Moattop 31% Innovationtop 34% Producttop 35% Newstop 38% Techtop 39% Growthtop 47% Globaltop 50% Marketbottom 43% Fin. healthbottom 32% Funding: Raised $785M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) AI: Classified as an AI company · Product described with: ai-based, machine learning rank vs industry peers · Fliar Intelligence Index 64/100 | $785M | 9 mo ago | Public | 27 | — | WordPressMySQLPHP+28 | 14 patents Small-molecule STING agonists and PI3Kβ inhibitors for immuno‑oncology therapeutics | 1 partnership |
| 5 | Generate Biomedicines 🦄 Developer of a platform for generating novel protein-based therapeutic modalities 78AI top 18%Funding top 23%News top 24%Innovation top 25% All 12 signals ▾AItop 18% Fundingtop 23% Newstop 24% Innovationtop 25% Growthtop 25% Patentstop 25% Moattop 25% Talenttop 28% Markettop 45% Techbottom 43% Globalbottom 42% Fin. healthbottom 39% AI: Classified as an AI company · Holds AI/ML patents (G06N-family CPC) Funding: Raised $643M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 78/100 | $643M | 18 mo ago | Public | 75 | Gevorg Grigoryan Co-Founder & CTO | Craft CMSApple iCloud MailPHP+17 | 36 patents Patents concentrated in chemistry & materials | — |
| 6 | Relay Therapeutics Developer of drug discovery platform and study protein motion | $520M | 29 mo ago | Public | 245 245 → 218 (-11%) | David Shaw Co-Founder | WordPressDrupalApple iCloud Mail+23 | 234 patents Small-molecule FGFR and PI3Kα kinase inhibitors for oncology applications | — |
| 7 | In Silico AI-enabled bioinformatics platform for drug discovery and biomarker development 82Funding top 15%Product top 19%AI top 20%News top 26% All 12 signals ▾Fundingtop 15% Producttop 19% AItop 20% Newstop 26% Partnerstop 26% Talenttop 28% Moattop 31% Innovationtop 35% Growthtop 35% Markettop 43% Techtop 46% Globalbottom 39% Funding: Raised $400M across 11 rounds · 11 rounds over 12 yrs (0.9/yr) Product: 3 distinct product lines · Company stage: Public rank vs industry peers · Fliar Intelligence Index 82/100 | $400M | 17 mo ago | Public | 300 | Alex Zhavoronkov Co-Founder & Co-CEO | SentryMUIReact+10 | — | — |
| 8 | Cellarity AI-powered drug design and development platform | $294M | 44 mo ago | Series C | 117 117 → 72 (-38%) | — | — | 26 patents AI-driven drug discovery and cellular diagnostic platforms using heterocyclic modulators | — |
| 9 | Tomorrow.io 🦄 AI-powered weather intelligence platform using satellites for real-time forecasting 89Funding top 16%Customers top 25%AI top 26%Moat top 26% All 11 signals ▾Fundingtop 16% Customerstop 25% AItop 26% Moattop 26% Producttop 27% Techtop 28% Talenttop 28% Newstop 30% Growthtop 37% Markettop 39% Globaltop 48% Funding: Raised $250M across 4 rounds · 4 rounds over 9 yrs (0.4/yr) Customers: Play-Store rating 4.57★ across 25,899 ratings (2 apps) · Review volume +2% in 6 mo rank vs industry peers · Fliar Intelligence Index 89/100 | $250M | 1 mo ago | Series F | 124 124 → 228 (+84%) | Hagit Messer Co-Founder | WordPressSentryZendesk+36 | — | 1 award |
| 10 | Motional Developer of technology for autonomous vehicles intended for ride-hail and delivery 84Innovation top 9%Patents top 9%AI top 18%Funding top 25% All 12 signals ▾Innovationtop 9% Patentstop 9% AItop 18% Fundingtop 25% Growthtop 35% Moattop 35% Markettop 42% Partnerstop 45% Techtop 48% Talentbottom 49% Globalbottom 42% Newsbottom 24% Innovation: 2,172 patents (top 1% of patent-holders) · 1931 filings since 2022 vs 241 in 2017-21 Patents: 2,172 patents matched (strict assignee match) · 1931 filings since 2022 vs 241 in 2017-21 rank vs industry peers · Fliar Intelligence Index 84/100 | $240M | 10 mo ago | Series B | 1,500 | Laura Major CEO | DrupalApple iCloud MailMariaDB+21 | 2,172 patents Autonomous vehicle software: sensor integration, control algorithms, validation, traffic management, and ride experience. | 2 job openings |
| 11 | Asimov Provider of integrated suite for advanced genetic design and manufacturing | $209M | 41 mo ago | Series B | 64 64 → 119 (+86%) | Chris Voigt Co-Founder | WebflowMicrosoft AdvertisingSendgrid+18 | 70 patents Efficient manufacturing of recombinant viral vectors for gene therapy applications | 1 launch · 1 partnership |
| 12 | Zappi Provider of a consumer insights platform delivering data and AI solutions | $200M | 42 mo ago | Series B | 119 | Steve Phillips Co-Founder & CIO | ContentfulMarkerApple iCloud Mail+25 | — | — |
| 13 | 7AI Provider of an agentic security platform using AI agents for cybersecurity 57Funding top 19%AI top 20%Growth top 28%Talent top 38% All 10 signals ▾Fundingtop 19% AItop 20% Growthtop 28% Talenttop 38% Moattop 48% Globalbottom 46% Techbottom 43% Marketbottom 40% Innovationbottom 30% Patentsbottom 26% Funding: Raised $166M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) AI: Classified as an AI company rank vs industry peers · Fliar Intelligence Index 57/100 | $166M | 6 mo ago | Series A | — | Yonatan Amit Co-Founder & CTO | HubSpot CMS HubFacebook LoginLinkedin Sign-in+19 | 2 patents Predictive analytics for customer journeys and targeted web advertising | — |
| 14 | Suno 🦄 Provider of music creation platform enabling users to easily create and share original songs 93Customers top 5%Funding top 19%Growth top 22%Tech top 24% All 10 signals ▾Customerstop 5% Fundingtop 19% Growthtop 22% Techtop 24% Moattop 26% Talenttop 28% AItop 30% Markettop 34% Producttop 40% Globalbottom 32% Customers: Play-Store rating 4.84★ across 1,750,077 ratings (1 apps) Funding: Raised $125M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 93/100 | $125M | 7 mo ago | Series C | — | Georg Kucsko Co-Founder & CTO | TurbopackEmotionSentry+39 | — | 2 launchs · 1 award |
| 15 | CODAMETRIX Provider of AI-based medical coding software for healthcare professionals 50Funding top 28%AI top 30%Tech top 36%Moat top 38% All 9 signals ▾Fundingtop 28% AItop 30% Techtop 36% Moattop 38% Talentbottom 49% Marketbottom 43% Growthbottom 36% Globalbottom 32% Newsbottom 21% Funding: Raised $97.4M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) AI: Classified as an AI company · Product described with: ai-based rank vs industry peers · Fliar Intelligence Index 50/100 | $97M | 14 mo ago | Series B | 68 68 → 114 (+68%) | Hamid Tabatabaie President and CEO | WordPressUptimeRobotAtlassian Statuspage+29 | — | 1 job opening |
| 16 | Pickle Robot Developer of AI-powered robotic systems for warehouse and supply chain automation | $95M | 26 mo ago | Series B | 18 | Dan Paluska Co-Founder | WordPressMySQLPHP+21 | — | 1 job opening · 2 launchs · 1 award |
| 17 | Realtime Robotics Developer of industrial AI software for robotic workcell automation solutions | $69M | 24 mo ago | Series B | 82 | Peter Howard Co-Founder & Chief Executive Officer | WordPressMySQLPHP+22 | 101 patents Multi-robot motion planning, environment modeling, and collision detection for dynamic workspaces | — |
| 18 | Eleos Health AI-based behavioral health diagnosis and management system for providers 80Funding top 25%AI top 26%Tech top 27%Talent top 28% All 10 signals ▾Fundingtop 25% AItop 26% Techtop 27% Talenttop 28% Growthtop 35% Producttop 40% Moattop 42% Marketbottom 49% Globalbottom 45% Newsbottom 18% Funding: Raised $68.0M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) AI: Classified as an AI company · Product described with: ai-based, ai-driven rank vs industry peers · Fliar Intelligence Index 80/100 | $68M | 16 mo ago | Series C | 106 | Alon Joffe Co-Founder & CEO | WordPressSentryApple iCloud Mail+51 | — | 1 launch |
| 19 | DeepCure Developer of novel small molecule therapies for immune diseases | $65M | 26 mo ago | Series A | — | Thrasyvoulos Karydis Co-Founder & CTO | Cart FunctionalitySquarespace CommerceSquarespace+12 | 10 patents AI-driven drug discovery and automated chemical synthesis workflow optimization | — |
| 20 | Neurable Developer of brain-computer interface technology for everyday devices 69AI top 20%Funding top 28%Innovation top 30%Patents top 30% All 12 signals ▾AItop 20% Fundingtop 28% Innovationtop 30% Patentstop 30% Moattop 34% Growthtop 35% Talenttop 38% Techtop 40% Globaltop 44% Productbottom 48% Marketbottom 39% Customersbottom 10% AI: Classified as an AI company Funding: Raised $56.8M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 69/100 | $57M | 5 mo ago | Series A | 30 | Ramses Alcaide Co-Founder & CEO | WebflowCart FunctionalityThree.js+34 | 46 patents Real-time neural signal processing for high-speed brain-computer and eye-tracking interfaces | 1 award |
| 21 | Marqvision Provider of counterfeiting solutions for e-commerce businesses | $46M | 9 mo ago | Series B | 100 | — | WebflowSentryZendesk+21 | — | 1 partnership |
| 22 | Posh Provider of AI platform and solutions for financial service institutions | $45M | 24 mo ago | Series A | 74 74 → 178 (+141%) | Karan Kashyap Co-Founder & CEO | WebflowAnimate.cssAmazon Web Services+30 | — | — |
| 23 | Rhino Provider of federated computing platform for secure data collaboration 60Funding top 25%AI top 30%Growth top 35%Patents top 42% All 9 signals ▾Fundingtop 25% AItop 30% Growthtop 35% Patentstop 42% Techtop 48% Globaltop 48% Innovationbottom 49% Talentbottom 49% Marketbottom 37% Funding: Raised $43.1M across 6 rounds · 6 rounds over 5 yrs (1.2/yr) AI: Classified as an AI company · Product described with: machine learning rank vs industry peers · Fliar Intelligence Index 60/100 | $43M | 5 mo ago | Series A | — | Yuval Baror Co-Founder & CTO | WebflowMicrosoft ClarityLinkedin Insight Tag+16 | 11 patents Marine docking structures and tensioned rock support bolt technologies | 1 launch |
| 24 | Liquid AI 🦄 Developer of efficient AI models and deployment platforms for various applications | $38M | 18 mo ago | Series A | — | Mathias Lechner Co-Founder & CTO | TurbopackSentryApple iCloud Mail+19 | — | 4 launchs · 1 award |
| 25 | Lightelligence Developer of optical chips and software solutions for artificial intelligence based computing 78AI top 20%Talent top 22%Funding top 28%Patents top 31% All 11 signals ▾AItop 20% Talenttop 22% Fundingtop 28% Patentstop 31% Moattop 32% Innovationtop 34% Growthtop 35% Markettop 46% Globalbottom 45% Newsbottom 42% Techbottom 41% AI: Classified as an AI company · Holds AI/ML patents (G06N-family CPC) Talent: Analyst team rating 5/5 · 3 named leaders on record rank vs industry peers · Fliar Intelligence Index 78/100 | $37M | 9 mo ago | Series C | 200 | John Joannopoulos Co-Founder | Apple iCloud MailMicrosoft 365Tengine+10 | 49 patents Photonic processors and optoelectronic computing hardware for high‑speed AI acceleration | — |
| 26 | 1910 Genetics Developer of small molecule therapeutics to treat pain and aging-related diseases | $30M | 19 mo ago | Series A | 18 | Jen Nwankwo Founder & CEO | — | — | — |
| 27 | Maven AGI Developer of an AI agent platform for customer experience automation 69AI top 20%Funding top 26%Tech top 28%Talent top 28% All 9 signals ▾AItop 20% Fundingtop 26% Techtop 28% Talenttop 28% Growthtop 35% Moattop 42% Globalbottom 36% Marketbottom 32% Newsbottom 18% AI: Classified as an AI company Funding: Raised $28.0M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 69/100 | $28M | 12 mo ago | Series B | — | Eugene Mann Co-Founder & CPO | WebflowAmazon Web ServicesAtlassian Statuspage+37 | — | — |
| 28 | Cimulate Provider of AI-powered search and customer experience optimization for e-commerce | $28M | 18 mo ago | Acquired | — | John Andrews Co-Founder & CEO | — | — | — |
| 29 | Videa Provider of practice management systems and imaging software for dental clinics | $26M | 16 mo ago | Series B | 52 | — | WebflowApple iCloud MailGoogle Workspace+24 | 11 patents Real-time perspective-corrected multi-screen video projection and signal switching systems | — |
| 30 | Kebotix AI solutions for materials discovery | $24M | 22 mo ago | Series B | 12 | Jill Becker CEO | — | 24 patents AI-driven molecular property prediction and automated synthesis for functional organic materials | — |
| 31 | Cyvl AI-powered mapping and management solution for transportation infrastructure 48Talent top 28%Funding top 29%AI top 30%Tech bottom 41% All 6 signals ▾Talenttop 28% Fundingtop 29% AItop 30% Techbottom 41% Globalbottom 33% Marketbottom 31% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $22.7M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $23M | 10 mo ago | Series A | — | Noah Parker Co-Founder | Webflow EcommerceWebflowMicrosoft Advertising+11 | — | — |
| 32 | Indico Data Developer of an agentic decisioning platform for insurance underwriting and claims 72AI top 8%Innovation top 23%Talent top 28%Funding top 33% All 11 signals ▾AItop 8% Innovationtop 23% Talenttop 28% Fundingtop 33% Moattop 39% Techtop 40% Producttop 49% Marketbottom 47% Globalbottom 43% Growthbottom 40% Newsbottom 38% AI: Classified as an agentic-AI company Innovation: 4 new-product events in 24 mo · Deep-tech classification: Artificial Intelligence, Agentic Ai rank vs industry peers · Fliar Intelligence Index 72/100 | $19M | 7 mo ago | Series B | 100 | Madison May Co-Founder & CTO | WordPressMySQLPHP+26 | — | — |
| 33 | Axiomatic AI Developer of verifiable AI for scientific and engineering applications 60Talent top 23%AI top 30%Funding top 34%Growth top 35% All 7 signals ▾Talenttop 23% AItop 30% Fundingtop 34% Growthtop 35% Globalbottom 48% Techbottom 42% Marketbottom 35% Talent: 6 named leaders on record · 6 C-suite/founder profiles curated AI: Classified as an AI company · Product described with: deep learning rank vs industry peers · Fliar Intelligence Index 60/100 | $18M | 3 mo ago | Seed | — | Alan Aspuru-Guzik Co-Founder
| JavaAstroCloudflare+6 | — | 2 launchs |
| 34 | Consensus Provider of an AI-enabled search tool for research purposes | $18M | 22 mo ago | Series B | 6 | Christian Salem Co-Founder | WordPressMySQLPHP+24 | — | 1 launch |
| 35 | Code Metal 🦄 Provider of AI-powered solutions for automated code translation and edge deployment | $16M | 3 mo ago | Series B | — | Richard Showalter-Bucher Founder | — | — | 6 job openings |
| 36 | Matterworks AI and analytical platform to accelerate therapeutic research | $16M | 12 mo ago | Series A | 14 | Jack Geremia Chief Executive Officer | Cart FunctionalitySquarespace CommerceSquarespace+16 | 12 patents Predictive mass‑spectrometry analytics and quantitative analyte measurement solutions. | 1 launch |
| 37 | Netpreme Developer of memory to compute networking solutions for AI infrastructure systems | $12M | 11 mo ago | Series B | — | Zhizhen Zhong Founder & CEO | TurbopackNode.jsRadix UI+12 | — | 1 job opening · 1 launch |
| 38 | Leo AI AI platform specifically for mechanical engineers and engineering firms | $10M | 9 mo ago | Seed | — | Maor Farid Co-Founder & CEO | Framer SitesYouTubeReact+15 | — | — |
| 39 | Nebulock Provider of agentic threat hunting platform automating complex threat detection | $8M | 10 mo ago | Seed | — | Damien Lewke Founder & CEO | WebflowApple iCloud MailGoogle Workspace+16 | — | — |
| 40 | Origin Medical AI powered platform to support prenatal care with an evaluation of pregnancy | $7M | 10 mo ago | Series A | — | Sripad Devalla Co-Founder & CEO | WebflowMicrosoft ClarityGoogle Analytics+14 | — | — |
| 41 | Revenue Base Provider of continuously verified and refreshed data for B2B sales teams | $7M | 20 mo ago | Seed | 35 | Mark Feldman Founder & CEO | WebflowGSAPAmazon Web Services+15 | — | 1 launch |
| 42 | XCaliber AI based platform offering a data intelligence cloud for healthcare 50AI top 26%Talent top 38%Funding top 44%Fin. health top 47% All 7 signals ▾AItop 26% Talenttop 38% Fundingtop 44% Fin. healthtop 47% Techtop 48% Globalbottom 49% Marketbottom 32% AI: Classified as an AI company · Product described with: ai based, ai powered Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 50/100 | $6M | 1 mo ago | Seed | — | Bhupender Kumar Co-Founder & Director of Product | WebflowApple iCloud MailAmazon Web Services+19 | — | — |
| 43 | OnCorps Developer of AI platform for fund operations and reporting reviews 74Growth top 20%AI top 20%Funding top 37%Tech top 47% All 8 signals ▾Growthtop 20% AItop 20% Fundingtop 37% Techtop 47% Moattop 48% Marketbottom 44% Globalbottom 43% Newsbottom 22% Growth: Headcount 28 → 46 (+64%) across vintages · Fresh capital in last 24 mo AI: Classified as an AI company rank vs industry peers · Fliar Intelligence Index 74/100 | $6M | 6 mo ago | Series C | 46 46 → 63 (+37%) | — | WebflowSalesforceAmazon Web Services+25 | — | 1 job opening |
| 44 | Salient Predictions Offering AI based solutions for weather forecasting | $6M | 15 mo ago | Series A | 2 | Ray Schmitt President & Co-founder | Webflowcore-jsjQuery+12 | 2 patents Neural-network ensemble blending for probabilistic weather forecasting | 1 launch |
| 45 | Cephable Developer of on-device AI software for workflow automation and content generation | $5M | 19 mo ago | Seed | — | Alexander Dunn Founder and CEO | WordPressMySQLMariaDB+27 | 3 patents Assistive technology enabling accessible human interface devices (e.g., adaptive input methods). | 1 award |
| 46 | Blitzy 🦄 AI powered IT application development platform 74Tech top 30%AI top 30%Moat top 31%Growth top 35% All 9 signals ▾Techtop 30% AItop 30% Moattop 31% Growthtop 35% Fundingtop 36% Talenttop 38% Markettop 50% Globalbottom 38% Newsbottom 18% Tech: 37 technologies across 5/8 capability areas · Cloud: Amazon S3, Amazon Web Services AI: Classified as an AI company · Product described with: ai powered rank vs industry peers · Fliar Intelligence Index 74/100 | $4M | 1 mo ago | Series B | — | Sid Pardeshi Co-Founder & CTO | FirebaseRadix UITailwind CSS+22 | — | 7 job openings |
| 47 | BITE Data Provider of trade compliance screening and supply chain risk mitigation tools | $3M | 7 mo ago | Seed | — | Anne Riitho Co-Founder & Chief Data Officer | WebflowAmazon Web ServicesLeadfeeder+20 | — | — |
| 48 | Drumkit Developer of an AI-powered platform for logistics and transportation management | $3M | 12 mo ago | Seed | — | Dhruv Gupta CEO and Co-Founder | — | — | — |
| 49 | Coworked Developer of AI project manager that integrates with existing systems 40AI top 20%Talent top 38%Funding top 43%Tech top 50% All 6 signals ▾AItop 20% Talenttop 38% Fundingtop 43% Techtop 50% Globalbottom 33% Marketbottom 25% AI: Classified as an AI company Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 40/100 | $2M | 1 mo ago | Seed | — | Shawn Harris Co-Founder & CEO | Framer SitesYouTubeReact+15 | — | — |
| 50 | Voda AI-enabled software solution for pipe breakage prediction | $1M | 12 mo ago | Series A | 25 | Jim Fitchett Chief Operating Officer & Co-Founder | WordPress Block EditorWordPressMySQL+32 | 9 patents Patents concentrated in computing, sensing & instrumentation | 2 launchs |
Top 12 Artificial Intelligence companies in Massachusetts
#1
Series F · Boston, Massachusetts · founded 2016 · 124 employees$250Mraised▾
AI-powered weather intelligence platform using satellites for real-time forecasting. It combines satellite data, machine learning, and real-time atmospheric modeling to deliver hyperlocal forecasts and predictive insights. It helps industries like aviation, energy, logistics, and insurance anticipate weather risks and automate operational decisions.
- May 2026Series F$35M
- Feb 2026Series F$175M
- Sep 2023Series E—
- Jun 2023Series E$87M
#2
XtalPi 🦄Public · Cambridge, Massachusetts · founded 2014 · 27 employees$784.8Mraised▾
XtalPi has developed a proprietary technology FACES(Fast Accurate Crystalline Engineering System), which is a cloud-based computing system to predict the crystal structure which will identify polymorphs of the compound. The company's algorithms are integrated with the Amazon Web Service (AWS) high-performance computing (HPC) resources in the cloud. The team claims to have a strong background in quantum physics and machine learning. It provides services to pharmaceutical companies at various stages of drug development. The company has deployed its technology to develop an Intelligent Digital Drug Discovery and Development (ID4) platform to improve the efficiency, accuracy, and success rate of drug discovery.
- Sep 2025Post IPO$268M
- Feb 2025Post IPO$268.4M
- Aug 2021Series D$400M
- Sep 2020Series C$318.8M
#3
Series A · Boston, Massachusetts · founded 2024$166Mraised▾
Provider of an agentic security platform using AI agents for cybersecurity. The platform offers capabilities including incident management, investigations, threat detection, automated response, and threat hunting. It provides tools for alert processing, data enrichment, and investigation summaries. The platform also offers features such as real-time dashboards, reporting, and custom workflow building.
- Dec 2025Series A$130M
- Feb 2025Seed$36M
#4
Suno 🦄Series C · Cambridge, Massachusetts · founded 2021$125Mraised▾
Provider of music creation platform enabling users to easily create and share original songs. It provides users with a music studio that enables users to create and share music through its intuitive platform, leveraging artificial intelligence to generate realistic songs. The company's mission is to democratize music creation and bridge the gap between artists and their compositions. By providing a user-friendly interface and accessible tools, Suno aims to empower individuals to produce high-quality music.
- Nov 2025Series C$250M
- May 2024Series B$125M
#5
Series A · Boston, Massachusetts · founded 2021$43.1Mraised▾
Provider of federated computing platform for secure data collaboration. This platform enables secure connection of decentralized data sources for analytics and machine learning without transferring raw data. It maintains data security, privacy, and sovereignty while facilitating insights generation from combined datasets. The platform allows for connection, processing, and scaling of federated networks, accelerating time to value for data collaborations. The solution is applicable across various sectors including healthcare, life sciences, and finance.
- Jan 2026Series A$11.3M
- May 2025Series A$15M
- Oct 2024Seed—
- Dec 2023Grant (prize money)$730.4K
#6
Series A · Boston, Massachusetts · founded 2015 · 30 employees$56.8Mraised▾
Developer of brain-computer interface technology for everyday devices. This technology allows users to interact with devices using brain signals. The company's offerings integrate seamlessly into existing devices, enhancing user experience and providing capabilities for focus tracking and fatigue prevention. The technology is designed for broad accessibility, extending beyond research applications to everyday use. Future applications are envisioned in wellness and clinical diagnostics.
- Dec 2025Series A$35M
- May 2024Series A$13M
- 2021Series A—
- Dec 2019Series A$6M
#7
Series B · Boston, Massachusetts · founded 2020 · 1500 employees$239.7Mraised▾
Developer of technology for autonomous vehicles intended for ride-hail and delivery. The company focuses on creating safe and reliable driverless vehicle solutions. It builds fully driverless vehicles designed for integration into mobility networks. The company develops technology and an experience for transportation and delivery solutions.
- Mar 2024Conventional Debt—
- Mar 2020Series D$239.7M
#8
Series B · Boston, Massachusetts · founded 2023$16.1Mraised▾
Provider of AI-powered solutions for automated code translation and edge deployment. The company facilitates the transition of research code into optimized, low-level code suitable for edge environments. It offers tools for defining runtime environments, including CPU, GPU, and FPGA configurations. The company automates the generation of code in languages such as C/C++, Rust, VHDL, Verilog, CUDA, HIP, and ONNX. It also provides features for tracking changes between generated and input code.
- Feb 2026Series B$125M
- Nov 2025Series A$36.5M
- Jun 2025Seed$6.5M
- Jul 2024Seed$13M
#9
Series D · Boston, Massachusetts · founded 2017 · 137 employees$850Mraised▾
Developer of photonic interconnects and co-packaged optics for AI infrastructure. The company’s technology addresses data center bottlenecks by connecting XPUs and switches. It offers solutions with lane speeds from 56G NRZ to 448G PAM4, bidirectional or unidirectional, and up to 16 wavelengths. The company also promotes open standards to drive adoption of advanced optical interconnect technologies.
- Oct 2024Series D$400M
- Jan 2024Series C—
- Dec 2023Series C$155M
- May 2023Series C$154M
#10
Seed · Cambridge, Massachusetts · founded 2024$18Mraised▾
Developer of verifiable AI for scientific and engineering applications. It integrates formal verification with deep learning to generate interpretable, consistent, and logically verifiable results. This approach reduces hallucinations and ensures mathematically verifiable, error-free outputs. It accelerates the creation of physics-based models, enabling accurate data extraction from technical documentation and optimization using experimental data. The AI capabilities accelerate photonic and semiconductor design, minimizing errors and speeding up development.
- Mar 2026Seed$18M
#11
Public · Somerville, Massachusetts · founded 2018 · 75 employees$643Mraised▾
Developer of a platform for generating novel protein-based therapeutic modalities. The platform aims to expand technical possibilities to change how medicines are made. It studies proteins to learn rules by which nature encodes function. The company generates medicines across therapeutic modalities with speed and success.
- Dec 2024Series C—
- Sep 2023Series C$273M
- Nov 2021Series B$370M
- Sep 2020Series A$50M
#12
Public · Cambridge, Massachusetts · founded 2014 · 300 employees$399.8Mraised▾
AI-enabled bioinformatics platform for drug discovery and biomarker development. The company provides solutions and services such as custom drug discovery engines, biomarker discovery, and aging research tools to academia, pharmaceutical, and cosmetics companies. Also, it has developed a product PHARMA.AI which includes modules for drug discovery such as PandaOmics, Chemistry42, and InClinico.
- Jan 2025Series E$110M
- Aug 2022Series D$35M
- Jun 2022Series D$60M
- Jun 2021Series C$255M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Artificial Intelligence coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Artificial Intelligence in Massachusetts is moving
A read on the academic research around Artificial Intelligence in Massachusetts — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 163 papers.
MIT, MGH, and UMass Amherst lead Massachusetts AI research, optimistically focused on neural networks, multimodal learning, and domain adaptation, with breakthroughs dominating and concern remaining a minority stance.
- Massachusetts Institute of Technology103
- Massachusetts General Hospital25
- University of Massachusetts Amherst18
- University of Massachusetts Lowell7
- University of Massachusetts Boston5
- Robustness (evolution)1→3
- Inference2→3
- Pattern recognition (psychology)4
- Context (archaeology)3
- Semantics (computer science)2
- Data mining2
- Cognition2
- Robot3
- Data science3
- Sight2
- Inference2
- Black box2