256 indexable Artificial Intelligence companies headquartered in Massachusetts, United States, ranked by total equity funding and recent funding momentum. Combined disclosed equity funding of $10.2B across 127 funded companies, including 10 unicorns.
| # | Company | Funding | Valuation | Stage | Latest round | Employees | Founded | Momentum |
|---|---|---|---|---|---|---|---|---|
| 1 |
Tomorrow.io
Unicorn AI-powered weather intelligence platform using satellites for real-time forecasting |
$250M | — | Series F | Series F May 2026 | 124 | 2016 | ↑ Active |
| 2 |
XtalPi
Unicorn AI-based drug research and development company |
$784.8M | $2B as of 2021 |
Public | Post IPO Sep 2025 | 27 | 2014 | ↑ Active |
| 3 |
7AI
Provider of an agentic security platform using AI agents for cybersecurity |
$166M | — | Series A | Series A Dec 2025 | — | 2024 | ↑ Active |
| 4 |
Suno
Unicorn Provider of music creation platform enabling users to easily create and share original songs |
$125M | $500M as of 2024 |
Series C | Series C Nov 2025 | — | 2021 | ↑ Active |
| 5 |
Rhino
Provider of federated computing platform for secure data collaboration |
$43.1M | — | Series A | Series A Jan 2026 | — | 2021 | ↑ Active |
| 6 |
Neurable
Developer of brain-computer interface technology for everyday devices |
$56.8M | — | Series A | Series A Dec 2025 | 30 | 2015 | ↑ Active |
| 7 |
Motional
Developer of technology for autonomous vehicles intended for ride-hail and delivery |
$239.7M | — | Series B | Series B Aug 2025 | 1,500 | 2020 | ↑ Active |
| 8 |
Code Metal
Unicorn Provider of AI-powered solutions for automated code translation and edge deployment |
$16.1M | — | Series B | Series B Feb 2026 | — | 2023 | ↑ Active |
| 9 |
Lightmatter
Unicorn Developer of photonic interconnects and co-packaged optics for AI infrastructure |
$850M | $4.4B as of 2024 |
Series D | Series D Oct 2024 | 137 | 2017 | ↑ Active |
| 10 |
Axiomatic AI
Developer of verifiable AI for scientific and engineering applications |
$18M | — | Seed | Seed Mar 2026 | — | 2024 | ↑ Active |
| 11 |
Generate Biomedicines
Unicorn Developer of a platform for generating novel protein-based therapeutic modalities |
$643M | $200B as of 2021 |
Public | Series C Dec 2024 | 75 | 2018 | ↑ Active |
| 12 |
In Silico
AI-enabled bioinformatics platform for drug discovery and biomarker development |
$399.8M | — | Public | Series E Jan 2025 | 300 | 2014 | ↑ Active |
| 13 |
XCaliber
AI based platform offering a data intelligence cloud for healthcare |
$6.5M | — | Seed | Seed May 2026 | — | 2022 | ↑ Active |
| 14 |
Marqvision
Provider of counterfeiting solutions for e-commerce businesses |
$46.3M | — | Series B | Series B Sep 2025 | 100 | 2019 | ↑ Active |
| 15 |
Blitzy
Unicorn AI powered IT application development platform |
$4.4M | — | Series B | Series B May 2026 | — | 2023 | ↑ Active |
| 16 |
Indico Data
Developer of an agentic decisioning platform for insurance underwriting and claims |
$19M | — | Series B | Series B Oct 2025 | 100 | 2014 | ↑ Active |
| 17 |
Lightelligence
Developer of optical chips and software solutions for artificial intelligence based computing |
$36.7M | — | Series C | Series C Sep 2025 | 200 | 2017 | ↑ Active |
| 18 |
CODAMETRIX
Provider of AI-based medical coding software for healthcare professionals |
$97.4M | — | Series B | Series B Apr 2025 | 68 | 2018 | ↑ Active |
| 19 |
Coworked
Developer of AI project manager that integrates with existing systems |
$1.8M | — | Seed | Seed May 2026 | — | 2023 | ↑ Active |
| 20 |
Snyk
Unicorn Provider of a platform securing code, models, and agents in applications |
$1.3B | $3.3B as of 2023 |
Series G | Series G Apr 2024 | 1,138 | 2015 | — |
| 21 |
OnCorps
Developer of AI platform for fund operations and reporting reviews |
$5.8M | — | Series C | Series C Dec 2025 | 46 | 2011 | ↑ Active |
| 22 |
Cyvl
AI-powered mapping and management solution for transportation infrastructure |
$22.7M | — | Series A | Series A Aug 2025 | — | 2020 | ↑ Active |
| 23 |
Maven AGI
Developer of an AI agent platform for customer experience automation |
$28M | — | Series B | Series B Jun 2025 | — | 2023 | ↑ Active |
| 24 |
Eleos Health
AI-based behavioral health diagnosis and management system for providers |
$68M | — | Series C | Series C Jan 2025 | 106 | 2019 | ↑ Active |
| 25 |
Leo AI
AI platform specifically for mechanical engineers and engineering firms |
$9.7M | — | Seed | Seed Sep 2025 | — | 2023 | ↑ Active |
| 26 |
Matterworks
AI and analytical platform to accelerate therapeutic research |
$15.9M | — | Series A | Series A Jun 2025 | 14 | 2019 | ↑ Active |
| 27 |
Netpreme
Developer of memory to compute networking solutions for AI infrastructure systems |
$11.7M | — | Series B | Series B Jun 2025 | — | 2024 | ↑ Active |
| 28 |
Videa
Provider of practice management systems and imaging software for dental clinics |
$26.4M | — | Series B | Series B Jan 2025 | 52 | 2018 | ↑ Active |
| 29 |
Nebulock
Provider of agentic threat hunting platform automating complex threat detection |
$8.5M | — | Seed | Seed Jul 2025 | — | 2024 | ↑ Active |
| 30 |
Origin Medical
AI powered platform to support prenatal care with an evaluation of pregnancy |
$7.2M | — | Series A | Series A Jul 2025 | — | 2019 | ↑ Active |
| 31 |
Relay Therapeutics
Developer of drug discovery platform and study protein motion |
$520M | — | Public | Post IPO Jan 2024 | 245 | 2016 | — |
| 32 |
Liquid AI
Unicorn Developer of efficient AI models and deployment platforms for various applications |
$37.6M | — | Series A | Series A Dec 2024 | — | 2023 | ↑ Active |
| 33 |
BITE Data
Provider of trade compliance screening and supply chain risk mitigation tools |
$3M | — | Seed | Seed Oct 2025 | — | 2022 | ↑ Active |
| 34 |
1910 Genetics
Developer of small molecule therapeutics to treat pain and aging-related diseases |
$29.8M | — | Series A | Series A Oct 2024 | 18 | 2018 | ↑ Active |
| 35 |
Cimulate
Provider of AI-powered search and customer experience optimization for e-commerce |
$28M | — | Acquired | Series A Dec 2024 | — | 2023 | ↑ Active |
| 36 |
Kebotix
AI solutions for materials discovery |
$23.7M | — | Series B | Series B Jul 2024 | 12 | 2017 | ↑ Active |
| 37 |
Pickle Robot
Developer of AI-powered robotic systems for warehouse and supply chain automation |
$95M | — | Series B | Series B Apr 2024 | 18 | 2018 | — |
| 38 |
Consensus
Provider of an AI-enabled search tool for research purposes |
$17.9M | — | Series B | Series B Aug 2024 | 6 | 2020 | ↑ Active |
| 39 |
Realtime Robotics
Developer of industrial AI software for robotic workcell automation solutions |
$68.9M | — | Series B | Series B May 2024 | 82 | 2016 | — |
| 40 |
Salient Predictions
Offering AI based solutions for weather forecasting |
$5.6M | — | Series A | Grant (prize money) Feb 2025 | 2 | 2017 | ↑ Active |
| 41 |
DataRobot
Unicorn Provider of an agent workforce platform for enterprise artificial intelligence |
$1.1B | $2.7B as of 2020 |
Series G | Series G Jun 2021 | 453 | 2012 | — |
| 42 |
Drumkit
Developer of an AI-powered platform for logistics and transportation management |
$2.6M | — | Seed | Seed 2025 | — | 2021 | ↑ Active |
| 43 |
Posh
Provider of AI platform and solutions for financial service institutions |
$45M | — | Series A | Series A Jun 2024 | 74 | 2018 | — |
| 44 |
DeepCure
Developer of novel small molecule therapies for immune diseases |
$64.6M | — | Series A | Series A Apr 2024 | — | 2018 | — |
| 45 |
Asimov
Provider of integrated suite for advanced genetic design and manufacturing |
$209.4M | — | Series B | Series B Jan 2023 | 64 | 2017 | — |
| 46 |
Voda
AI-enabled software solution for pipe breakage prediction |
$1.4M | — | Series A | Series A Jun 2025 | 25 | 2017 | ↑ Active |
| 47 |
Cellarity
AI-powered drug design and development platform |
$294M | — | Series C | Series C Oct 2022 | 117 | 2015 | — |
| 48 |
Revenue Base
Provider of continuously verified and refreshed data for B2B sales teams |
$6.6M | — | Seed | Seed Sep 2024 | 35 | 2020 | ↑ Active |
| 49 |
Zappi
Provider of a consumer insights platform delivering data and AI solutions |
$200M | — | Series B | Series B Dec 2022 | 119 | 2013 | — |
| 50 |
Cephable
Developer of on-device AI software for workflow automation and content generation |
$4.6M | — | Seed | Seed Oct 2024 | — | 2021 | ↑ Active |
AI-powered weather intelligence platform using satellites for real-time forecasting. It combines satellite data, machine learning, and real-time atmospheric modeling to deliver hyperlocal forecasts and predictive insights. It helps industries like aviation, energy, logistics, and insurance anticipate weather risks and automate operational decisions.
XtalPi has developed a proprietary technology FACES(Fast Accurate Crystalline Engineering System), which is a cloud-based computing system to predict the crystal structure which will identify polymorphs of the compound. The company's algorithms are integrated with the Amazon Web Service (AWS) high-performance computing (HPC) resources in the cloud. The team claims to have a strong background in quantum physics and ma
Provider of an agentic security platform using AI agents for cybersecurity. The platform offers capabilities including incident management, investigations, threat detection, automated response, and threat hunting. It provides tools for alert processing, data enrichment, and investigation summaries. The platform also offers features such as real-time dashboards, reporting, and custom workflow building.
Provider of music creation platform enabling users to easily create and share original songs. It provides users with a music studio that enables users to create and share music through its intuitive platform, leveraging artificial intelligence to generate realistic songs. The company's mission is to democratize music creation and bridge the gap between artists and their compositions. By providing a user-friendly inte
Provider of federated computing platform for secure data collaboration. This platform enables secure connection of decentralized data sources for analytics and machine learning without transferring raw data. It maintains data security, privacy, and sovereignty while facilitating insights generation from combined datasets. The platform allows for connection, processing, and scaling of federated networks, accelerating
Developer of brain-computer interface technology for everyday devices. This technology allows users to interact with devices using brain signals. The company's offerings integrate seamlessly into existing devices, enhancing user experience and providing capabilities for focus tracking and fatigue prevention. The technology is designed for broad accessibility, extending beyond research applications to everyday use. Fu
Developer of technology for autonomous vehicles intended for ride-hail and delivery. The company focuses on creating safe and reliable driverless vehicle solutions. It builds fully driverless vehicles designed for integration into mobility networks. The company develops technology and an experience for transportation and delivery solutions.
Provider of AI-powered solutions for automated code translation and edge deployment. The company facilitates the transition of research code into optimized, low-level code suitable for edge environments. It offers tools for defining runtime environments, including CPU, GPU, and FPGA configurations. The company automates the generation of code in languages such as C/C++, Rust, VHDL, Verilog, CUDA, HIP, and ONNX. It al
Developer of photonic interconnects and co-packaged optics for AI infrastructure. The company’s technology addresses data center bottlenecks by connecting XPUs and switches. It offers solutions with lane speeds from 56G NRZ to 448G PAM4, bidirectional or unidirectional, and up to 16 wavelengths. The company also promotes open standards to drive adoption of advanced optical interconnect technologies.
Developer of verifiable AI for scientific and engineering applications. It integrates formal verification with deep learning to generate interpretable, consistent, and logically verifiable results. This approach reduces hallucinations and ensures mathematically verifiable, error-free outputs. It accelerates the creation of physics-based models, enabling accurate data extraction from technical documentation and optimi
Developer of a platform for generating novel protein-based therapeutic modalities. The platform aims to expand technical possibilities to change how medicines are made. It studies proteins to learn rules by which nature encodes function. The company generates medicines across therapeutic modalities with speed and success.
AI-enabled bioinformatics platform for drug discovery and biomarker development. The company provides solutions and services such as custom drug discovery engines, biomarker discovery, and aging research tools to academia, pharmaceutical, and cosmetics companies. Also, it has developed a product PHARMA.AI which includes modules for drug discovery such as PandaOmics, Chemistry42, and InClinico.
MIT Startup Exchange
_1584095064231.png){kind=logo}
Techstars
E14 Fund
MIT Alumni Angels of Boston
Y Combinator
MassChallenge
National Science Foundation
Google Ventures
Hyperplane
Right Side Capital Management
Flybridge Capital Partners
In-Q-Tel
Rankings are computed by Radar (Fliar BI) from the Radar company master and are updated periodically. Funding and momentum scores use disclosed equity-funding data only. Figures may lag private rounds. Last updated 2026-06-18.
_1583468353822.png){kind=logo}
_1530167378194.png){kind=logo}
_1584095703505.png){kind=logo}
_1537422048749.png){kind=logo}
