Best HealthTech Companies in Massachusetts, United States
The 1296 best HealthTech companies in Massachusetts, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Amwell.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in Massachusetts
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | XtalPi 🦄 AI-based drug research and development company 64Funding top 18%AI top 26%Talent top 28%Patents top 31% All 13 signals ▾Fundingtop 18% AItop 26% Talenttop 28% Patentstop 31% Moattop 31% Innovationtop 34% Producttop 35% Newstop 38% Techtop 39% Growthtop 47% Globaltop 50% Marketbottom 43% Fin. healthbottom 32% Funding: Raised $785M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) AI: Classified as an AI company · Product described with: ai-based, machine learning rank vs industry peers · Fliar Intelligence Index 64/100 | $785M | 9 mo ago | Public | 27 | — | 14 patents Small-molecule STING agonists and PI3Kβ inhibitors for immuno‑oncology therapeutics | 1 partnership |
| 2 | Generate Biomedicines 🦄 Developer of a platform for generating novel protein-based therapeutic modalities 78AI top 18%Funding top 23%News top 24%Innovation top 25% All 12 signals ▾AItop 18% Fundingtop 23% Newstop 24% Innovationtop 25% Growthtop 25% Patentstop 25% Moattop 25% Talenttop 28% Markettop 45% Techbottom 43% Globalbottom 42% Fin. healthbottom 39% AI: Classified as an AI company · Holds AI/ML patents (G06N-family CPC) Funding: Raised $643M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 78/100 | $643M | 17 mo ago | Public | 75 | Gevorg Grigoryan Co-Founder & CTO | 36 patents Patents concentrated in chemistry & materials | — |
| 3 | Whoop 🦄 Provider of wearable trackers to monitor fitness data 94Tech top 9%Innovation top 11%Funding top 14%Patents top 15% All 12 signals ▾Techtop 9% Innovationtop 11% Fundingtop 14% Patentstop 15% Customerstop 19% Moattop 22% Markettop 23% Newstop 23% Talenttop 28% Producttop 32% Growthtop 42% Globalbottom 48% Tech: 83 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Innovation: 248 patents (top 4% of patent-holders) · 171 filings since 2022 vs 56 in 2017-21 rank vs industry peers · Fliar Intelligence Index 94/100 | $406M | 2 mo ago | Series G | 453 | Aurelian Nicolae Co-Founder & Chief Hardware Engineer | 248 patents Patents concentrated in health & consumer products | 1 partnership |
| 4 | In Silico AI-enabled bioinformatics platform for drug discovery and biomarker development 82Funding top 15%Product top 19%AI top 20%News top 26% All 12 signals ▾Fundingtop 15% Producttop 19% AItop 20% Newstop 26% Partnerstop 26% Talenttop 28% Moattop 31% Innovationtop 35% Growthtop 35% Markettop 43% Techtop 46% Globalbottom 39% Funding: Raised $400M across 11 rounds · 11 rounds over 12 yrs (0.9/yr) Product: 3 distinct product lines · Company stage: Public rank vs industry peers · Fliar Intelligence Index 82/100 | $400M | 17 mo ago | Public | 300 | Alex Zhavoronkov Co-Founder & Co-CEO | — | — |
| 5 | Caresyntax Analytics & integration platform to improve surgical outcomes 64Funding top 19%Product top 25%Moat top 31%Growth top 32% All 10 signals ▾Fundingtop 19% Producttop 25% Moattop 31% Growthtop 32% Innovationtop 34% Techtop 43% Talentbottom 49% Globalbottom 45% Marketbottom 43% Newsbottom 22% Funding: Raised $302M across 8 rounds · 8 rounds over 9 yrs (0.9/yr) Product: 6 distinct product lines · Company stage: Series C rank vs industry peers · Fliar Intelligence Index 64/100 | $302M | 22 mo ago | Series C | 64 64 → 140 (+119%) · sector median +59% | Dennis Kogan Founder and CEO | — | — |
| 6 | Iterative Health Provider of AI-based device for endoscopic images of gastroenterological diseases 78Growth top 13%Funding top 18%AI top 25%Moat top 31% All 7 signals ▾Growthtop 13% Fundingtop 18% AItop 25% Moattop 31% Techbottom 47% Marketbottom 44% Globalbottom 37% Growth: Headcount 22 → 75 (+241%) across vintages · Fresh capital in last 24 mo Funding: Raised $194M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 78/100 | $194M | 1 mo ago | Series C | 75 75 → 177 (+136%) · sector median +59% | — | — | — |
| 7 | Overjet Provider of AI-powered dental imaging and claims processing solutions 57Funding top 24%Tech top 27%AI top 28%Talent top 28% All 11 signals ▾Fundingtop 24% Techtop 27% AItop 28% Talenttop 28% Growthtop 35% Patentstop 36% Innovationtop 42% Globalbottom 49% Moatbottom 43% Marketbottom 26% Fin. healthbottom 20% Funding: Raised $159M across 5 rounds · 5 rounds over 6 yrs (0.8/yr) Tech: 44 technologies across 5/8 capability areas · Cloud: Amazon S3, Amazon Web Services rank vs industry peers · Fliar Intelligence Index 57/100 | $159M | 6 mo ago | Series C | — | Wardah Inam Co-Founder & CEO | 16 patents AI-driven dental radiograph analysis, enhancement, and craniofacial measurement automation | — |
| 8 | Harbinger Health AI-based cancer detection tool for providers 55Funding top 18%News top 36%Moat top 42%AI top 45% All 8 signals ▾Fundingtop 18% Newstop 36% Moattop 42% AItop 45% Talenttop 49% Techbottom 48% Marketbottom 43% Globalbottom 38% Funding: Raised $140M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) News: 2 BI events in 12 mo (of 13 tracked, 3 types) · Top themes: Leadership rank vs industry peers · Fliar Intelligence Index 55/100 | $140M | 2 mo ago | Series B | 60 | Stephen Hahn CEO | — | 2 launchs |
| 9 | Diagonal Therapeutics Developer of antibody therapeutics for the treatment of rare diseases 40Funding top 19%Moat top 42%Talent bottom 49%Market bottom 40% All 5 signals ▾Fundingtop 19% Moattop 42% Talentbottom 49% Marketbottom 40% Globalbottom 38% Funding: Raised $128M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Moat: Editorial + unicorn rating 5/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 40/100 | $128M | 5 mo ago | Series B | — | Alexey Lugovskoy CEO | — | — |
| 10 | Elucid AI-based arterial analysis software for providers 80Growth top 13%Funding top 16%Talent top 38%Moat top 39% All 8 signals ▾Growthtop 13% Fundingtop 16% Talenttop 38% Moattop 39% AItop 45% Marketbottom 44% Globalbottom 37% Newsbottom 27% Growth: Headcount 6 → 28 (+367%) across vintages · Fresh capital in last 24 mo Funding: Raised $121M across 7 rounds · 7 rounds over 4 yrs (1.8/yr) rank vs industry peers · Fliar Intelligence Index 80/100 | $121M | 8 mo ago | Series C | 28 | James Hamilton Co-Founder | — | — |
| 11 | Stipple Bio Provider of a platform that utilizes epitope-level resolution to unlock cellular profiling and target… 21Funding top 20%Talent top 38%Global bottom 48%Tech bottom 25% All 5 signals ▾Fundingtop 20% Talenttop 38% Globalbottom 48% Techbottom 25% Marketbottom 19% Funding: Raised $109M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 21/100 | $109M | 2 mo ago | Series A | 2 | Aaron Ring Co-Founder | — | 1 partnership |
| 12 | Cohere Health Provider of prior authorization solutions to improve patient care 62Funding top 24%Moat top 31%Tech top 38%Market top 39% All 8 signals ▾Fundingtop 24% Moattop 31% Techtop 38% Markettop 39% Growthtop 45% Talentbottom 49% Globalbottom 36% Newsbottom 18% Funding: Raised $106M across 3 rounds · 3 rounds over 6 yrs (0.5/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 62/100 | $106M | 13 mo ago | Series C | 570 | Siva Namasivayam Chief Executive Officer | — | — |
| 13 | Atavistik Developer of allosteric therapeutics for precision oncology and rare diseases 50Funding top 19%Talent top 28%Moat top 31%Market bottom 42% All 6 signals ▾Fundingtop 19% Talenttop 28% Moattop 31% Marketbottom 42% Globalbottom 36% Newsbottom 33% Funding: Raised $100M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 50/100 | $100M | 3 mo ago | Series B | 33 | Ralph DeBerardinis Co-Founder | — | — |
| 14 | TetraScience Provider of a cloud-based data platform for life science industry 40Funding top 21%Growth top 26%Moat top 35%Tech top 50% All 9 signals ▾Fundingtop 21% Growthtop 26% Moattop 35% Techtop 50% Newsbottom 47% Globalbottom 39% Marketbottom 38% Patentsbottom 25% Innovationbottom 22% Funding: Raised $99.2M across 6 rounds · 6 rounds over 12 yrs (0.5/yr) Growth: Headcount 13 → 30 (+131%) across vintages · Web rank 5,000,000 → 10,000,000 YoY rank vs industry peers · Fliar Intelligence Index 40/100 | $99M | 4 mo ago | Series B | 30 | — | 4 patents Real-time monitoring and feedback control systems for industrial tools and equipment | 1 job opening |
| 15 | CODAMETRIX Provider of AI-based medical coding software for healthcare professionals 50Funding top 28%AI top 30%Tech top 36%Moat top 38% All 9 signals ▾Fundingtop 28% AItop 30% Techtop 36% Moattop 38% Talentbottom 49% Marketbottom 43% Growthbottom 36% Globalbottom 32% Newsbottom 21% Funding: Raised $97.4M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) AI: Classified as an AI company · Product described with: ai-based rank vs industry peers · Fliar Intelligence Index 50/100 | $97M | 14 mo ago | Series B | 68 68 → 114 (+68%) · sector median +59% | Hamid Tabatabaie President and CEO | — | 1 job opening |
| 16 | AcuityMD Platform offering CRM software to the medical industry 53Funding top 18%News top 25%Talent top 28%Growth top 35% All 10 signals ▾Fundingtop 18% Newstop 25% Talenttop 28% Growthtop 35% Producttop 36% Moattop 39% Techtop 48% Marketbottom 42% Innovationbottom 37% Globalbottom 34% Funding: Raised $83.0M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) News: 4 BI events in 12 mo (of 11 tracked, 3 types) · Top themes: Funding, New product rank vs industry peers · Fliar Intelligence Index 53/100 | $83M | 1 mo ago | Series C | 48 | Michael Monovoukas Co-Founder & CEO | — | — |
| 17 | Eleos Health AI-based behavioral health diagnosis and management system for providers 80Funding top 25%AI top 26%Tech top 27%Talent top 28% All 10 signals ▾Fundingtop 25% AItop 26% Techtop 27% Talenttop 28% Growthtop 35% Producttop 40% Moattop 42% Marketbottom 49% Globalbottom 45% Newsbottom 18% Funding: Raised $68.0M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) AI: Classified as an AI company · Product described with: ai-based, ai-driven rank vs industry peers · Fliar Intelligence Index 80/100 | $68M | 16 mo ago | Series C | 106 | Alon Joffe Co-Founder & CEO | — | 1 launch |
| 18 | Ampersand Developer of programmable medicines to treat multiple diseases 42AI top 15%Funding top 24%Talent top 38%Moat top 40% All 10 signals ▾AItop 15% Fundingtop 24% Talenttop 38% Moattop 40% Growthtop 43% Patentsbottom 45% Techbottom 43% Globalbottom 38% Innovationbottom 30% Marketbottom 29% AI: Holds AI/ML patents (G06N-family CPC) Funding: Raised $65.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $65M | 14 mo ago | Series B | 22 | Raffi Afeyan Co-Founder & Chief Innovation Officer | 5 patents Audio signal analysis and filtering, plus multidimensional GUI for database interaction | 1 partnership |
| 19 | MedRhythms Provider of wearable devices to combat neurological injuries and recover walking functions 80Funding top 19%Growth top 20%Moat top 25%Product top 30% All 12 signals ▾Fundingtop 19% Growthtop 20% Moattop 25% Producttop 30% Innovationtop 33% Patentstop 34% Talenttop 34% AItop 45% Markettop 46% Techbottom 46% Globalbottom 40% Newsbottom 22% Funding: Raised $57.1M across 7 rounds · 7 rounds over 8 yrs (0.9/yr) Growth: Headcount 22 → 41 (+86%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 80/100 | $57M | 4 mo ago | Series B | 41 41 → 59 (+44%) · sector median +59% | Brian Harris Co-Founder & CEO | 44 patents Patents concentrated in health & consumer products | — |
| 20 | Metaphore Provider of machine language and computational platform for drug discovery 42Funding top 23%Talent top 28%Moat top 42%AI top 45% All 7 signals ▾Fundingtop 23% Talenttop 28% Moattop 42% AItop 45% Globalbottom 36% Techbottom 35% Marketbottom 31% Funding: Raised $50.0M across 1 rounds · 1 rounds over 3 yrs (0.3/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 42/100 | $50M | 2 mo ago | Series C | 30 | Noubar Afeyan Co-Founder | — | — |
| 21 | Psithera Online retailer of plant-based products focused on health and wellness 45Funding top 22%Talent bottom 49%Global bottom 33% All 3 signals ▾Fundingtop 22% Talentbottom 49% Globalbottom 33% Funding: Raised $47.5M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 45/100 | $48M | 6 mo ago | Series A | — | Eric Shaff CEO & President | — | — |
| 22 | Counsel Health Virtual medical practice that offers healthcare through messaging based care 50Funding top 26%Tech top 32%Talent bottom 49%Global bottom 48% All 5 signals ▾Fundingtop 26% Techtop 32% Talentbottom 49% Globalbottom 48% Marketbottom 40% Funding: Raised $36.0M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Tech: 33 technologies across 5/8 capability areas · Cloud: Amazon Web Services, Cloudflare rank vs industry peers · Fliar Intelligence Index 50/100 | $36M | 8 mo ago | Series A | — | Muthu Alagappan Founder & CEO | — | 1 partnership · 1 award |
| 23 | Pi Health Provider of an AI-native platform for managing clinical trials end-to-end 62Patents top 20%Moat top 21%Growth top 28%Innovation top 31% All 11 signals ▾Patentstop 20% Moattop 21% Growthtop 28% Innovationtop 31% Fundingtop 31% Talenttop 38% AItop 45% Techbottom 47% Globalbottom 45% Marketbottom 29% Newsbottom 18% Patents: 9,865 patents matched (strict assignee match) · 2246 filings since 2022 vs 3287 in 2017-21 Moat: Editorial + unicorn rating 7/10 · IP moat: 9,865 patents rank vs industry peers · Fliar Intelligence Index 62/100 | $31M | 4 mo ago | Series A | — | Bobby Reddy Md Co-Founder and COO | 9,865 patents Cell-based immunotherapies, engineered NK/CAR cells, and PET imaging agents for oncology | 1 job opening |
| 24 | AOA Provider of an AI-enabled early detection platform focused on womens health 45Funding top 24%Patents top 27%Talent top 28%Innovation top 33% All 8 signals ▾Fundingtop 24% Patentstop 27% Talenttop 28% Innovationtop 33% Moattop 47% Globalbottom 44% Marketbottom 21% Newsbottom 18% Funding: Raised $30.7M across 7 rounds · 7 rounds over 5 yrs (1.4/yr) Patents: 22 patents matched (strict assignee match) · 21 filings since 2022 vs 1 in 2017-21 rank vs industry peers · Fliar Intelligence Index 45/100 | $31M | 8 mo ago | Series A | 3 | Alex Fisher Co-Founder & COO | 22 patents Patents concentrated in health & consumer products | 1 award |
| 25 | Wysa Provider of AI-driven mental health support platform 60Customers top 22%Funding top 28%Talent top 28%Partners top 41% All 15 signals ▾Customerstop 22% Fundingtop 28% Talenttop 28% Partnerstop 41% Moattop 41% Growthtop 44% AItop 45% Producttop 46% Fin. healthtop 48% Markettop 50% Patentstop 50% Techbottom 49% Globalbottom 47% Innovationbottom 41% Newsbottom 24% Customers: Play-Store rating 4.54★ across 154,836 ratings (3 apps) · Review volume +1% in 6 mo Funding: Raised $30.5M across 10 rounds · 10 rounds over 11 yrs (0.9/yr) rank vs industry peers · Fliar Intelligence Index 60/100 | $31M | 4 mo ago | Series B | 104 104 → 177 (+70%) · sector median +59% | Jo Aggarwal Founder & CEO | 3 patents AI chatbot sentiment alignment and mismatch detection for personalized conversational therapy | 1 partnership |
| 26 | Beacon Biosignals AI-based EEG analysis and diagnosis platform for healthcare providers 67News top 22%Funding top 24%Growth top 25%Talent top 28% All 12 signals ▾Newstop 22% Fundingtop 24% Growthtop 25% Talenttop 28% Moattop 41% AItop 45% Producttop 46% Techtop 48% Patentstop 50% Innovationbottom 49% Marketbottom 44% Globalbottom 37% News: 5 BI events in 12 mo (of 5 tracked, 1 types) · 5 high-value events (IPO/M&A/funding/contracts) in 12 mo Funding: Raised $30.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 67/100 | $30M | 2 mo ago | Series B | 37 | Jacob Donoghue Co-Founder & CEO | 4 patents EEG-based neurodiagnostic platforms for Alzheimer’s biomarkers, trial assessment, and neurotoxicity | — |
| 27 | Biobot Analytics Provider of tools to map microbes and chemicals of interest 53Growth top 26%Funding top 32%Moat top 41%Tech top 46% All 10 signals ▾Growthtop 26% Fundingtop 32% Moattop 41% Techtop 46% Talentbottom 49% Marketbottom 46% Patentsbottom 40% Innovationbottom 39% Globalbottom 37% Newsbottom 33% Growth: Headcount 38 → 98 (+158%) across vintages · Web rank 10,000,000 → 50,000,000 YoY Funding: Raised $29.2M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 53/100 | $29M | 12 mo ago | Series A | 98 | Mariana Matus Co-Founder & CEO | 4 patents Modular upstream wastewater sampling systems for population health surveillance | — |
| 28 | Lumia Health Developer of wearable ear devices tracking blood flow to head 64Funding top 28%Growth top 28%Tech top 29%Talent top 38% All 6 signals ▾Fundingtop 28% Growthtop 28% Techtop 29% Talenttop 38% Globalbottom 48% Marketbottom 40% Funding: Raised $29.1M across 3 rounds · 3 rounds over 1 yrs (3.0/yr) Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 64/100 | $29M | 2 mo ago | Series B | — | Paul Jin Co-Founder | — | — |
| 29 | Persivia AI-driven digital health platform for value-based care success 57Funding top 28%Moat top 31%Product top 33%Tech top 41% All 10 signals ▾Fundingtop 28% Moattop 31% Producttop 33% Techtop 41% Innovationtop 42% Patentstop 44% AItop 45% Marketbottom 43% Globalbottom 31% Newsbottom 21% Funding: Raised $28.0M across 7 rounds · 7 rounds over 16 yrs (0.4/yr) Moat: Editorial + unicorn rating 7/10 · IP moat: 9 patents rank vs industry peers · Fliar Intelligence Index 57/100 | $28M | 13 mo ago | Series D | 60 | — | 9 patents Clinical decision support and patient prioritization analytics for health data management | — |
| 30 | Nanopath Provider of point-of-care molecuolar diagnostic platform for womens health 72Innovation top 27%Funding top 29%Patents top 29%Moat top 32% All 6 signals ▾Innovationtop 27% Fundingtop 29% Patentstop 29% Moattop 32% Talentbottom 45% Globalbottom 31% Innovation: 38 patents (top 31% of patent-holders) · 25 filings since 2022 vs 13 in 2017-21 Funding: Raised $24.1M across 7 rounds · 7 rounds over 4 yrs (1.8/yr) rank vs industry peers · Fliar Intelligence Index 72/100 | $24M | 13 mo ago | Series A | — | Amogha Tadimety Co-Founder & Co-CEO | 38 patents Nanoplasmonic biosensor platforms for multiplexed pathogen and analyte detection | — |
| 31 | Ketryx Provider of AI-native compliance software for regulated medical applications development 45Funding top 30%Tech top 40%AI top 45%Growth top 48% All 9 signals ▾Fundingtop 30% Techtop 40% AItop 45% Growthtop 48% Talentbottom 49% Moatbottom 48% Marketbottom 32% Newsbottom 31% Globalbottom 29% Funding: Raised $18.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) Tech: 36 technologies across 5/8 capability areas · Cloud: Amazon Web Services, Cloudflare rank vs industry peers · Fliar Intelligence Index 45/100 | $18M | 11 mo ago | Series B | 19 | Erez Kaminski CEO | — | — |
| 32 | Liberating Technologies Research and development for advanced prosthetic upper limb technology 29Product top 26%Funding top 30%Innovation top 34%Tech bottom 30% All 6 signals ▾Producttop 26% Fundingtop 30% Innovationtop 34% Techbottom 30% Globalbottom 29% Marketbottom 27% Product: 6 distinct product lines · Company stage: Acquired Funding: Raised $16.2M across 19 rounds · 19 rounds over 17 yrs (1.1/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $16M | 12 mo ago | Acquired | 13 | — | — | — |
| 33 | Genialis Developer of end-to-end bioinformatics software solutions 53Funding top 33%Growth top 35%Moat top 37%Patents top 38% All 10 signals ▾Fundingtop 33% Growthtop 35% Moattop 37% Patentstop 38% Innovationtop 39% Talenttop 41% Producttop 46% Techtop 50% Globalbottom 44% Marketbottom 35% Funding: Raised $15.3M across 6 rounds · 6 rounds over 11 yrs (0.5/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $15M | 6 mo ago | Series A | 35 | Rafael Rosengarten Chief Executive Officer | 17 patents Patents concentrated in computing, sensing & instrumentation | 1 launch |
| 34 | Rendever Provider of a virtual reality platform for elderly care 55Innovation top 23%Funding top 34%Growth top 35%Product top 48% All 8 signals ▾Innovationtop 23% Fundingtop 34% Growthtop 35% Producttop 48% Moattop 48% Techtop 50% Marketbottom 34% Globalbottom 29% Innovation: 4 product lines · Deep-tech classification: Tech Hardware Funding: Raised $15.1M across 8 rounds · 8 rounds over 9 yrs (0.9/yr) rank vs industry peers · Fliar Intelligence Index 55/100 | $15M | 7 mo ago | Funding Raised | 24 24 → 34 (+42%) · sector median +59% | — | — | 1 launch · 1 partnership |
| 35 | Red Queen Bio Developer of AI-enabled biodefense countermeasures to address emerging biological threats 65Funding top 33%Talent top 45%Global bottom 48% All 3 signals ▾Fundingtop 33% Talenttop 45% Globalbottom 48% Funding: Raised $15.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 2 named leaders on record rank vs industry peers · Fliar Intelligence Index 65/100 | $15M | 7 mo ago | Seed | — | Hannu Rajaniemi Co-Founder | — | — |
| 36 | RISA Labs Provider of solutions for automating clinical operation 57Funding top 27%Talent top 28%Growth top 35%AI top 45% All 7 signals ▾Fundingtop 27% Talenttop 28% Growthtop 35% AItop 45% Techbottom 45% Marketbottom 35% Globalbottom 33% Funding: Raised $14.6M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 57/100 | $15M | 5 mo ago | Series A | — | Kumar Shivang Co-Founder & CTO | — | — |
| 37 | Family First Provider of caregiving solutions dedicated to supporting people caring for aging parents 53Funding top 28%Growth top 35%Tech top 37%Moat top 39% All 8 signals ▾Fundingtop 28% Growthtop 35% Techtop 37% Moattop 39% Talentbottom 49% Productbottom 48% Marketbottom 42% Globalbottom 32% Funding: Raised $14.5M across 5 rounds · 5 rounds over 3 yrs (1.7/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $14M | 4 mo ago | Series A | 53 | Evan Falchuk Chief Executive Officer | — | — |
| 38 | Seven Starling Online community platform for pregnancy and parenting 45Tech top 33%Funding top 35%Talent top 38%Growth top 40% All 7 signals ▾Techtop 33% Fundingtop 35% Talenttop 38% Growthtop 40% Newstop 48% Globalbottom 29% Marketbottom 28% Tech: 37 technologies across 5/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Funding: Raised $13.8M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 45/100 | $14M | 9 mo ago | Series A | 21 | Tina Beilinson Co-Founder & CEO | — | — |
| 39 | Phylo Developer of collaborative agents designed for biologists to accelerate discoveries 42Funding top 32%Talent top 38%Tech top 40%Market bottom 37% All 5 signals ▾Fundingtop 32% Talenttop 38% Techtop 40% Marketbottom 37% Globalbottom 33% Funding: Raised $13.5M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 42/100 | $14M | 4 mo ago | Seed | — | Yuanhao Qu Co-Founder & President | — | 1 launch · 3 partnerships |
| 40 | Synthpop AI-powered clinical management software 62Growth top 28%News top 32%Funding top 37%Talent top 38% All 9 signals ▾Growthtop 28% Newstop 32% Fundingtop 37% Talenttop 38% Techtop 42% AItop 45% Moattop 48% Marketbottom 36% Globalbottom 36% Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo News: 3 BI events in 12 mo (of 7 tracked, 1 types) · Top themes: Funding rank vs industry peers · Fliar Intelligence Index 62/100 | $11M | 10 mo ago | Series A | — | Jan Jannink Co-Founder & CTO | — | — |
| 41 | Outcome Referrals AI-powered behavioral health platform matching patients with optimal providers for better outcomes 24AI top 35%Funding top 41%Talent bottom 45%Tech bottom 43% All 6 signals ▾AItop 35% Fundingtop 41% Talentbottom 45% Techbottom 43% Globalbottom 29% Marketbottom 23% AI: Product described with: ai-powered, artificial intelligence Funding: Raised $6.6M across 6 rounds · 6 rounds over 14 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 24/100 | $7M | 8 mo ago | Seed | 15 15 → 19 (+27%) · sector median +59% | Roger Urban CEO | — | — |
| 42 | XCaliber AI based platform offering a data intelligence cloud for healthcare 50AI top 26%Talent top 38%Funding top 44%Fin. health top 47% All 7 signals ▾AItop 26% Talenttop 38% Fundingtop 44% Fin. healthtop 47% Techtop 48% Globalbottom 49% Marketbottom 32% AI: Classified as an AI company · Product described with: ai based, ai powered Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 50/100 | $6M | 1 mo ago | Seed | — | Bhupender Kumar Co-Founder & Director of Product | — | — |
| 43 | NeoSoma Provider of an AI-based image analysis and decision-making platform for neurooncologist 40AI top 28%Funding top 40%Patents top 40%Moat top 42% All 8 signals ▾AItop 28% Fundingtop 40% Patentstop 40% Moattop 42% Innovationtop 48% Talentbottom 49% Globalbottom 35% Marketbottom 29% AI: Holds AI/ML patents (G06N-family CPC) · Product described with: ai-based Funding: Raised $6.3M across 5 rounds · 5 rounds over 6 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 40/100 | $6M | 3 mo ago | Series B | 13 | Ken Kolodziej Co-Founder & CEO | 7 patents AI-driven MRI segmentation and volumetric analysis of high-grade brain gliomas | — |
| 44 | Folia Provider of a platform for health tracking of children 53Tech top 25%Growth top 28%Talent top 34%Funding top 38% All 10 signals ▾Techtop 25% Growthtop 28% Talenttop 34% Fundingtop 38% Producttop 40% Moattop 47% Innovationbottom 43% Globalbottom 31% Marketbottom 30% Patentsbottom 26% Tech: 44 technologies across 6/8 capability areas · Cloud: Cloudflare Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $6M | 8 mo ago | Series A | 20 | Nell Luo Founder & CEO | 2 patents Bio-based polymer synthesis and polysuccinimide derivative manufacturing | — |
| 45 | Flourish Care Provider of a tech-enabled maternal health platform 42Growth top 35%Tech top 37%Funding top 41%Talent bottom 49% All 6 signals ▾Growthtop 35% Techtop 37% Fundingtop 41% Talentbottom 49% Globalbottom 33% Marketbottom 31% Growth: Fresh capital in last 24 mo Tech: 47 technologies across 4/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 rank vs industry peers · Fliar Intelligence Index 42/100 | $6M | 2 mo ago | Deadpooled | — | Melissa Bowley Founder | — | — |
| 46 | BrainCo Provider of a prosthetic hand and EEG headband for brain signal 35Funding top 40%Growth top 43%Moat bottom 49%Talent bottom 49% All 9 signals ▾Fundingtop 40% Growthtop 43% Moatbottom 49% Talentbottom 49% Patentsbottom 48% Techbottom 46% Globalbottom 42% Innovationbottom 40% Marketbottom 36% Funding: Raised $5.5M across 2 rounds · 2 rounds over 10 yrs (0.2/yr) Growth: Headcount 43 → 40 (-7%) across vintages · Web rank 50,000,000 → 10,000,000 YoY rank vs industry peers · Fliar Intelligence Index 35/100 | $6M | 5 mo ago | Series A | 40 | Bicheng Han Founder & CEO | 10 patents Neurofeedback-driven brain‑computer interfaces for personalized learning and robotic control | — |
| 47 | BIOMETRY Predictive asthma management through biomarker data and personalized insights 32Moat top 32%Innovation top 33%Patents top 35%Funding top 40% All 6 signals ▾Moattop 32% Innovationtop 33% Patentstop 35% Fundingtop 40% Globalbottom 40% Marketbottom 24% Moat: Editorial + unicorn rating 4/10 · IP moat: 42 patents Innovation: 42 patents (top 29% of patent-holders) · 18 filings since 2022 vs 20 in 2017-21 rank vs industry peers · Fliar Intelligence Index 32/100 | $5M | 6 mo ago | Seed | 10 | — | 42 patents Portable gas chromatography test strips for rapid point‑of‑care chemical analyte detection | — |
| 48 | a2z Radiology AI AI based platform offering solutions for radiological diagnostics 29Talent top 38%Funding top 39%AI top 45%Tech bottom 41% All 6 signals ▾Talenttop 38% Fundingtop 39% AItop 45% Techbottom 41% Globalbottom 33% Marketbottom 25% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $4.5M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $4M | 6 mo ago | Seed | — | Pranav Rajpurkar Co-Founder | — | — |
| 49 | Stata DX Provider of liquid MRI-based platform for neurological diseases 11Funding top 46%Talent bottom 49%Global bottom 30%Market bottom 24% All 4 signals ▾Fundingtop 46% Talentbottom 49% Globalbottom 30% Marketbottom 24% Funding: Raised $4.5M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 11/100 | $4M | 3 mo ago | Seed | 10 | Michal Depa Co-Founder | — | — |
| 50 | QSimulate Laboratory focused on developing of quantitative simulation tools to help in quantum molecular 32Growth top 35%Talent top 38%Funding top 41%Moat top 48% All 7 signals ▾Growthtop 35% Talenttop 38% Fundingtop 41% Moattop 48% Techbottom 36% Globalbottom 36% Marketbottom 24% Growth: Fresh capital in last 24 mo Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 32/100 | $4M | 6 mo ago | Seed | 14 14 → 21 (+50%) · sector median +59% | Toru Shiozaki Co-Founder & CEO | — | 1 job opening |
Top 12 HealthTech companies in Massachusetts
#1
Whoop 🦄Series G · Boston, Massachusetts · founded 2012 · 453 employees$405.7Mraised▾
Provider of wearable trackers to monitor fitness data. The devices track sleep patterns, strain levels, recovery metrics, and stress indicators. The data collected helps users make informed decisions regarding their fitness, health, and lifestyle choices. The fitness trackers offer insights into sleep optimization, activity tracking, and personalized guidance based on individual cycles.
- Mar 2026Series G$575M
- Nov 2022Angel—
- Aug 2021Series F$200M
- Oct 2020Series E$100M
#2
Series C · Cambridge, Massachusetts · founded 2017 · 75 employees$193.5Mraised▾
Provider of AI-based device for endoscopic images of gastroenterological diseases. The platform interprets endoscopic pictures and other forms of data using machine learning and computer vision, allowing clinicians to better diagnose patients with possible GI disorders. "SKOUT" is a polyp detection system that employs artificial intelligence to assist gastroenterologists in detecting more adenomas during colonoscopy.
- May 2026Series C$77M
- Jan 2022Series B$150M
- Aug 2021Series A$30M
- Jan 2020Seed$13.5M
#3
Series B · Cambridge, Massachusetts · founded 2008 · 60 employees$140Mraised▾
AI-based cancer detection tool for providers. The company has developed a blood test detection tool that enables professionals to analyze and detect early cancers.
- Apr 2026Series B$100M
- Sep 2023Series B$140M
- 2021Series A$50M
#4
XtalPi 🦄Public · Cambridge, Massachusetts · founded 2014 · 27 employees$784.8Mraised▾
XtalPi has developed a proprietary technology FACES(Fast Accurate Crystalline Engineering System), which is a cloud-based computing system to predict the crystal structure which will identify polymorphs of the compound. The company's algorithms are integrated with the Amazon Web Service (AWS) high-performance computing (HPC) resources in the cloud. The team claims to have a strong background in quantum physics and machine learning. It provides services to pharmaceutical companies at various stages of drug development. The company has deployed its technology to develop an Intelligent Digital Drug Discovery and Development (ID4) platform to improve the efficiency, accuracy, and success rate of drug discovery.
- Sep 2025Post IPO$268M
- Feb 2025Post IPO$268.4M
- Aug 2021Series D$400M
- Sep 2020Series C$318.8M
#5
Series C · Boston, Massachusetts · founded 2018 · 48 employees$83Mraised▾
Platform offering CRM software to the medical industry. The platform enables members to personalize customer engagement, identify and quantify opportunities, forecast sales accurately, understand the value of the sales pipeline, empower the sales team, track new launches, understand product adoption and market penetration.
- Apr 2026Series C$80M
- Jun 2024Series B$45M
- May 2022Series A$31M
- May 2021Series A$7M
#6
Series A · Cambridge, Massachusetts · founded 2021 · 2 employees$109.5Mraised▾
Provider of a platform that utilizes epitope-level resolution to unlock cellular profiling and target discovery. The platform technology enables single-cell profiling and target identification for ddrug discovery and development of cancer immunotherapy and others.
- Mar 2026Series A$100M
- Dec 2024Series A$9.5M
#7
Series B · Cambridge, Massachusetts · founded 2021 · 33 employees$100Mraised▾
Developer of allosteric therapeutics for precision oncology and rare diseases. The company integrated with proprietary drug discovery platform that enables to unlock novel allosteric binding pockets and rapidly advance structural insights into small molecule therapeutics designt to unlock cryptic allosteric sites across a broad range of target classes.
- Mar 2026Series B$40M
- Dec 2025Series B$120M
- Dec 2023Series A$40M
- Aug 2021Series A$60M
#8
Series B · Boston, Massachusetts · founded 2014 · 30 employees$99.2Mraised▾
Provider of a cloud-based data platform for life science industry. It provides a platform that automatically gathers scientific data from lab equipment, gets data ready for analysis and display, and re-engineers raw or primary data into harmonised data.
- Feb 2026Series B$15M
- Apr 2021Series B$80M
- 2020Series A$11M
- Oct 2019Series A$8M
#9
Series C · Boston, Massachusetts · founded 2018$158.9Mraised▾
Provider of AI-powered dental imaging and claims processing solutions. It offers software that assists dentists in diagnosing oral diseases with greater precision, educating patients using annotated images, and automating insurance claims for faster processing. The platform also provides tools for insurers to efficiently review claims. The solutions aim to improve the efficiency and accuracy of dental care while streamlining administrative tasks for both providers and payers.
- Dec 2025Series C$24.6M
- Feb 2024Series C$56.7M
- Dec 2021Series B$42.5M
- Aug 2021Series A$27.2M
#10
Series B · Cambridge, Massachusetts · founded 2022$128Mraised▾
Developer of antibody therapeutics for the treatment of rare diseases. The company's DIAGONAL platform combines proprietary computational and experimental techniques to develop agonist antibody therapies for hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension.
- Jan 2026Series B$125M
- Apr 2024Series A$128M
#11
Series B · Boston, Massachusetts · founded 2013 · 41 employees$57.1Mraised▾
Provider of wearable devices to combat neurological injuries and recover walking functions. The company has developed inertial measurement unit (IMU) sensors to measure gait parameters and run proprietary algorithms on them to make changes to the music accordingly. It uses artificial intelligence to personalize and improve the algorithm over time, as well as make predictive insights about the user population.
- Feb 2026Series B$3.3M
- Mar 2025Series B$2.9M
- Nov 2023Series B$19.8M
- Feb 2023Series B$5.8M
#12
Series C · Cambridge, Massachusetts · founded 2021 · 30 employees$50Mraised▾
Provider of machine language and computational platform for drug discovery. The company uses biomimicry and machine learning to unleash the transformational medicinal potential of functional molecular mimics. The MIMiC platform, developed by the company is a computationally driven bioplatform for developing novel therapies in which function, specificity, and selectivity may be optimized.
- Apr 2026Series C—
- May 2023Series C$50M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health in Massachusetts is moving
A read on the academic research around Digital Health in Massachusetts — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 245 papers.
MGH, MIT, and UMass Chan lead Massachusetts' digital-health research, focusing on AI, mHealth, and telehealth with a cautiously optimistic tone balancing advancement against concern.
- Massachusetts General Hospital96
- Massachusetts Institute of Technology59
- University of Massachusetts Chan Medical School43
- University of Massachusetts Amherst14
- University of Massachusetts Boston13
- Health care1→3
- Data sharing1→3
- Health informatics2→3
- Health care1→19
- Health informatics2→16
- Public health1→11
- Psychological intervention2→12
- Wearable computer2→10
- Health care3→30
- Public health1→10
- Health informatics6→13
- eHealth1→6
- Data science1→6