Radar · Orthopedics in Massachusetts
Best Orthopedics Companies in Massachusetts, United States
The 76 best Orthopedics companies in Massachusetts, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Vor Biopharma.
By Riya SenguptaFinancials
76companies tracked
$2.9Bdisclosed funding
0unicorns
41have raised
FLIAR INTELLIGENCE · ORTHOPEDICS × MASSACHUSETTS
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
50companies analysed
82%cloud-native stacks
2025funding peak (by rounds)
2015median founding year
40median Fliar Index™
134kcombined LinkedIn audience
49%of audience held by top 3
3companies hiring publicly (12 mo)
Ranked: Best Orthopedics companies in Massachusetts
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Vor Biopharma Developer of therapeutics to treat acute myeloid leukemia 78Funding top 12%Patents top 19%Innovation top 20%News top 24% All 10 signals ▾Fundingtop 12% Patentstop 19% Innovationtop 20% Newstop 24% Talenttop 27% Moattop 35% Growthtop 39% Techtop 40% Markettop 47% Globalbottom 40% Funding: Raised $477M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) Patents: 188 patents matched (strict assignee match) · 154 filings since 2022 vs 34 in 2017-21 rank vs industry peers · Fliar Intelligence Index 78/100 | $477M | 6 mo ago | 133 | 2019 | Siddhartha Mukherjee Founder | WordPressApple iCloud MailMySQL+29 | 188 patents Advanced genome editing platforms and engineered cell therapies for hematopoietic applications | — |
| 2 | ConforMIS Developer of 3D-printed orthopedic products | $447M | 80 mo ago | 242 | 2004 | Mark Augusti CEO | — | 684 patents Patient-specific orthopedic knee implants and surgical guides for tibial resection | — |
| 3 | Radius Health Biopharmaceutical company focused on bone health and related therapeutic areas | $238M | 48 mo ago | 291 | 2003 | Scott Briggs Chief Executive Officer | WordPress Block EditorWordPressApple iCloud Mail+19 | 306 patents Peptide-based osteoporosis and spinal fusion therapies using abaloparatide analogs. | — |
| 4 | Barricaid Provider of annular closure implants for the treatment of lumbar disc herniations | $197M | 30 mo ago | 49 49 → 91 (+86%) | 2006 | Jacob Einhorn Co-Founder & Chief Technology Officer | WordPress Block EditorElementorWordPress+29 | — | — |
| 5 | Entrada Therapeutics Developer of the biologics-based platform to treat rare diseases | $175M | 62 mo ago | 122 122 → 202 (+66%) | 2016 | Dipal Doshi CEO & President | Craft CMSApple iCloud MailPHP+20 | — | — |
| 6 | Intrinsic Therapeutics Reconstruction solutions for spinal disc defects | $139M | 109 mo ago | 49 | 2000 | Cary Hagan CEO & President | — | — | — |
| 7 | Lifeward Developer of exoskeletons for individuals with spinal cord injuries and stroke rehabilitation 50Funding top 22%Product top 28%News top 30%Partners top 31% All 13 signals ▾Fundingtop 22% Producttop 28% Newstop 30% Partnerstop 31% Techtop 40% Growthtop 47% Moattop 47% Markettop 48% Patentstop 50% Talentbottom 49% Innovationbottom 48% Fin. healthbottom 40% Globalbottom 39% Funding: Raised $132M across 13 rounds · 13 rounds over 15 yrs (0.9/yr) Product: 1 published app (39 installs) · Company stage: Public rank vs industry peers · Fliar Intelligence Index 50/100 | $132M | 3 mo ago | — | 2001 | Larry Jasinski CEO & MD | WordPressMySQLPHP+31 | 3 patents Provides advanced differential air pressure exercise and unweighting fitness equipment. | — |
| 8 | Histogenics Developer of restorative cell therapies for orthopedic diseases | $116M | 117 mo ago | 84 | 2000 | — | — | 121 patents Adhesive scaffolds and porous matrices for articular cartilage regeneration. | — |
| 9 | Solid Biosciences Developer of gene therapy platform for Duchenne muscular dystrophy 53Patents top 20%Funding top 24%Innovation top 31%Tech top 33% All 10 signals ▾Patentstop 20% Fundingtop 24% Innovationtop 31% Techtop 33% Moattop 38% Newstop 48% Marketbottom 49% Growthbottom 44% Globalbottom 42% Fin. healthbottom 32% Patents: 60 patents matched (strict assignee match) · 43 filings since 2022 vs 17 in 2017-21 Funding: Raised $92.5M across 7 rounds · 7 rounds over 11 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 53/100 | $92M | 3 mo ago | 101 | 2014 | — | WordPressApple iCloud MailMySQL+22 | 60 patents AAV gene‑therapy vector production, formulation, and cardiomyopathy therapeutic constructs | — |
| 10 | Biogen Developer of therapies for neurodegenerative and immunology disorders | $80M | 28 mo ago | 9,482 | 1978 | Heinz Co-Founder | DrupalAdobe Experience ManagerApple iCloud Mail+25 | 3,803 patents Therapeutic biologics, antibodies, and gene‑therapy vectors for neuro‑immune diseases | — |
| 11 | Miach Orthopaedics Developer of surgical implants for connective tissue repair 64Funding top 23%Talent top 28%Patents top 32%Moat top 32% All 10 signals ▾Fundingtop 23% Talenttop 28% Patentstop 32% Moattop 32% Growthtop 35% Innovationtop 39% Techtop 48% Marketbottom 46% Globalbottom 42% Newsbottom 22% Funding: Raised $72.5M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) Talent: Analyst team rating 5/5 · 2 named leaders on record rank vs industry peers · Fliar Intelligence Index 64/100 | $72M | 1 mo ago | 46 | 2016 | Martha Murray Founder | WordPressMySQLPHP+21 | 33 patents Injectable collagen-based implants for orthopedic tissue repair and regeneration | — |
| 12 | DeepCure Developer of novel small molecule therapies for immune diseases | $65M | 26 mo ago | — | 2018 | Thrasyvoulos Karydis Co-Founder & CTO | Cart FunctionalitySquarespace CommerceSquarespace+12 | 10 patents AI-driven drug discovery and automated chemical synthesis workflow optimization | — |
| 13 | Flexion Therapeutics Developer of therapies for the treatment of musculoskeletal disorders | $62M | 109 mo ago | 692 | 2007 | — | — | — | — |
| 14 | Consano Bio Developer of biologic therapeutic engineered for orthopedic conditions treatment 35Funding top 28%Talent bottom 49%Global bottom 25% All 3 signals ▾Fundingtop 28% Talentbottom 49% Globalbottom 25% Funding: Raised $51.7M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 35/100 | $52M | 3 mo ago | — | 2023 | Andrew Hall CEO | — | — | — |
| 15 | Theradaptive Developer of protein engineering technology creating targeted therapeutics for tissue repair | $50M | 25 mo ago | 10 | 2004 | — | WordPressPleskMySQL+20 | 73 patents Bone-targeted therapeutics and regenerative biomaterials for cancer and skeletal repair | — |
| 16 | NeuroTherm Minimally invasive solutions for chronic pain including radiofrequency catheters and abation systems | $50M | 183 mo ago | 127 | 2005 | — | — | 29 patents Neuromodulation devices for diagnosing/treating neural disorders and spinal disc therapy | — |
| 17 | HydroCision Developer of therapeutic devices for spine surgery 57Innovation top 20%Patents top 20%Funding top 27%Moat top 28% All 9 signals ▾Innovationtop 20% Patentstop 20% Fundingtop 27% Moattop 28% Growthtop 35% Producttop 35% Techtop 49% Globalbottom 36% Marketbottom 28% Innovation: 113 patents (top 17% of patent-holders) · 32 filings since 2022 vs 13 in 2017-21 Patents: 113 patents matched (strict assignee match) · 32 filings since 2022 vs 13 in 2017-21 rank vs industry peers · Fliar Intelligence Index 57/100 | $47M | 19 mo ago | 20 20 → 34 (+70%) | 1994 | — | WordPressMySQLPHP+26 | 111 patents Advanced surgical instruments for tissue removal, dynamic stents, and precision pump control. | 1 partnership |
| 18 | Hyalex Developer of a synthetic cartilage platform to restore damaged joint surfaces | $46M | 21 mo ago | 18 18 → 23 (+28%) | 2016 | Carl Vause Chief Executive Officer | WordPress Block EditorWordPressMySQL+20 | — | — |
| 19 | Orthopedic Synergy Manufacturer of reconstructive orthopedic devices for joints & bones | $43M | 141 mo ago | — | 2008 | — | — | — | — |
| 20 | OMNILife Sciences Orthopaedic technology innovator enhancing patient well-being with robotic and AI solutions | $33M | 96 mo ago | 113 | 1999 | — | — | — | — |
| 21 | Bion X Medical Technologies Developer of lower limb prosthesis | $32M | 126 mo ago | 20 | 2006 | Chuck Carignan President & CEO | — | — | — |
| 22 | ReWalk Robotics Provider of a wearable exoskeleton hardware suite for patients with disabilities | $28M | 63 mo ago | 24 | 2001 | Amit Goffer Founder | — | — | — |
| 23 | Facet Solutions Spinal Implants | $26M | 194 mo ago | 17 | 2003 | — | — | 434 patents Patents concentrated in health & consumer products | — |
| 24 | RevBio Developer of synthetic adhesive used for bone/dental repair 57Talent top 23%Innovation top 28%Patents top 28%Funding top 34% All 7 signals ▾Talenttop 23% Innovationtop 28% Patentstop 28% Fundingtop 34% Moattop 38% Marketbottom 37% Globalbottom 31% Talent: 5 named leaders on record · 5 C-suite/founder profiles curated Innovation: 50 patents (top 31% of patent-holders) · 44 filings since 2022 vs 6 in 2017-21 rank vs industry peers · Fliar Intelligence Index 57/100 | $24M | 13 mo ago | 29 | 2014 | Michael Brown Co-Founder | — | 50 patents Medical bioadhesives and bone fixation devices for surgical and image‑guided applications | — |
| 25 | Myomo Provider of a robotic arm for mobility and rehabilitation | $17M | 80 mo ago | 80 80 → 136 (+70%) | 2004 | Paul Gudonis Chief Executive Officer | WordPressMySQLPHP+21 | 38 patents Upper‑limb powered orthotic/exoskeleton devices for grasp assistance and rehabilitation. | — |
| 26 | Liberating Technologies Research and development for advanced prosthetic upper limb technology 29Product top 26%Funding top 30%Innovation top 34%Tech bottom 30% All 6 signals ▾Producttop 26% Fundingtop 30% Innovationtop 34% Techbottom 30% Globalbottom 29% Marketbottom 27% Product: 6 distinct product lines · Company stage: Acquired Funding: Raised $16.2M across 19 rounds · 19 rounds over 17 yrs (1.1/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $16M | 12 mo ago | 13 | 2001 | — | — | — | — |
| 27 | Serica Technologies Silk based scaffold for soft tissue repair | $12M | 219 mo ago | 15 | 1998 | Greg Altman Founder & ex-CEO | — | 8 patents Silk‑based biocompatible scaffolds and prosthetic devices for tendon/ligament regeneration | — |
| 28 | VisionScope Technologies Provider of minimally-invasive, arthroscopic imaging technology | $10M | 184 mo ago | 6 | 2007 | Hjalmar Pompe van Meerdervoort CEO | — | 42 patents Minimally invasive arthroscopic surgery tools and fiber‑optic miniature endoscopes. | — |
| 29 | Myolex Innovating muscle assessment technology for neuromuscular disorders and muscle wasting diseases 35Moat top 38%Funding top 45%Talent top 45%Patents bottom 43% All 6 signals ▾Moattop 38% Fundingtop 45% Talenttop 45% Patentsbottom 43% Innovationbottom 36% Globalbottom 31% Moat: Editorial + unicorn rating 4/10 · IP moat: 8 patents Funding: Raised $9.7M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 35/100 | $10M | 13 mo ago | — | 2016 | Jerry Panos CEO | — | 8 patents Electrical impedance myography sensors for muscle tissue assessment and bioimpedance measurement. | — |
| 30 | ArthroMeda Innovative solutions for improved arthroplasty surgery using micro-sensors and software | $8M | 58 mo ago | — | 2011 | PJ Anand Co-founder | — | 41 patents Custom orthopedic prosthesis alignment and pelvis registration for patient-specific joint replacement | — |
| 31 | Skeletalis Developer of targeted small-molecule therapies for musculoskeletal health and bone regeneration 37Talent top 38%Funding top 43%Global bottom 33% All 3 signals ▾Talenttop 38% Fundingtop 43% Globalbottom 33% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $8.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 37/100 | $8M | 7 mo ago | — | 2025 | Benton Swanson Co-Founder & CEO | — | — | — |
| 32 | Cure Rare Disease Developer of therapeutics to treat rare neuromuscular diseases | $8M | 16 mo ago | 21 | 2017 | Rich Horgan Founder & CEO | Webflow EcommerceWebflowVimeo+17 | — | — |
| 33 | NanoHive Developer of spinal interbody fusion implants | $7M | 22 mo ago | 15 15 → 18 (+20%) | 2014 | Patrick O’Donnell CEO | WordPressMySQLPHP+23 | — | — |
| 34 | Bone Biologics Provider of orthobiologic regenerative medicine | $7M | 31 mo ago | 2 | 2004 | Chia Soo Founder | WordPress Block EditorwpBakeryWordPress+12 | — | 1 launch |
| 35 | Remedium Bio Developer of gene therapies for a broad range of diseases 7Funding top 37%Moat top 48%Global bottom 36%Tech bottom 22% All 5 signals ▾Fundingtop 37% Moattop 48% Globalbottom 36% Techbottom 22% Marketbottom 20% Funding: Raised $5.6M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) Moat: Editorial + unicorn rating 4/10 · 10 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 7/100 | $6M | 1 mo ago | 5 | 2020 | — | Google MapsBootstrapNginx+6 | — | — |
| 36 | Arthrosurface 3-D printed implants for damaged joints | $5M | 219 mo ago | 50 | 2001 | — | WordPress Block EditorCart FunctionalityWooCommerce+37 | 378 patents Shoulder arthroplasty implants and related surgical instrumentation for humeral and glenoid reconstruction | — |
| 37 | MX Orthopedics Nitinol based hip implant devices | $4M | 134 mo ago | 5 | 2008 | — | — | 116 patents Patents concentrated in health & consumer products | — |
| 38 | LAPIX Developer of immunotherapies for immunological diseases | $3M | 11 mo ago | 9 | 2019 | Anas Fathallah Co-Founder & CEO | WordPressMySQLPHP+16 | — | — |
| 39 | NuOrtho Surgical Platform technologies for tissue preservation | $3M | 174 mo ago | — | 2008 | Wayne Auge Co-Founder | — | 47 patents Advanced electrosurgical scalpels and RF probes for precise tissue cutting and coagulation. | — |
| 40 | Ortholevo Developer of therapeutics for the treatment of fibrosis | $2M | 22 mo ago | — | 2016 | Mark Grinstaff Co-Founder | — | — | — |
| 41 | Endocellutions Concentrated regeneration solutions using advanced cell separation technology for point-of-care applications | $1M | 113 mo ago | 3 | 2010 | — | — | 38 patents Minimally invasive bone‑marrow and tissue harvesting devices with integrated cell‑processing systems | — |
| 42 | Lenoss Medical Developer of implants for the treatment of spinal fractures 11Funding top 47%Talent bottom 49%Global bottom 29%Market bottom 23% All 4 signals ▾Fundingtop 47% Talentbottom 49% Globalbottom 29% Marketbottom 23% Funding: Raised $1.3M across 2 rounds · 2 rounds over 5 yrs (0.4/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 11/100 | $1M | 3 mo ago | 9 | 2016 | Dom Messerli CEO & President | — | — | 1 partnership |
| 43 | Articulate Biosciences Develops a portfolio of medical devices for orthopedics disease | $852K | 96 mo ago | — | 2016 | Benjamin Cooper CEO | — | — | — |
| 44 | InVivo Therapeutics Developer of devices for the treatment of spinal cord injuries | $300K | 44 mo ago | 6 | 2005 | — | — | — | — |
| 45 | Tatum Robotics Provider of tactile-sign language robots | $256K | 40 mo ago | 10 | 2021 | Samantha Johnson Founder | — | — | 1 award |
| 46 | RegenX Developer of treatments for musculoskeletal injury-related issues | $256K | 69 mo ago | 5 | 2017 | — | — | — | — |
| 47 | Gate Science Developer of a multi-modal device for post-surgery pain | $150K | 42 mo ago | 7 | 2020 | Neil Bodick Co-Founder & CEO | — | — | — |
Top 12 Orthopedics companies in Massachusetts
#1
Public · Cambridge, Massachusetts · founded 2019 · 133 employees$477.1Mraised▾
Public · Cambridge, Massachusetts · founded 2019 · 133 employees
Developer of therapeutics to treat acute myeloid leukemia. The company has developed cancer therapeutics using engineered hematopoietic stem cells (eHSC). The company's lead candidate includes VOR33 which targets CD33 protein in cancer patients to treat acute myeloid leukemia (AML).
Fliar Intelligence Index™ 78how this company ranks against its industry peers
Funding
top 12%Patents
top 19%Innovation
top 20%News
top 24%Talent
top 27%Moat
top 35%Funding: Raised $477M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) · Last round Post IPO (Dec 2025)
Patents: 188 patents matched (strict assignee match) · 154 filings since 2022 vs 34 in 2017-21 · Latest publication 2026
Innovation: 188 patents (top 13% of patent-holders) · 154 filings since 2022 vs 34 in 2017-21
Funding rounds
- Dec 2025Post IPO$150M
- Jun 2025Post IPO$175M
- Jul 2020Series B$110.1M
- Feb 2019Series A$42M
Founders & team
Investors
RA Capital Management, Forbion, Venrock, Caligan Partners, NEXTBio, Mingxin Capital
Tech stack
AddtoanyAddtoany Share ButtonsApple Icloud MailCloudflareCloudflare Bot ManagementCookiebot
#2
Public · Marlborough, Massachusetts · founded 2001$131.6Mraised▾
Public · Marlborough, Massachusetts · founded 2001
Developer of exoskeletons for individuals with spinal cord injuries and stroke rehabilitation. The company offerings include the rewalk personal exoskeleton, restore exo-suit, and myocycle FES systems for rehabilitation, recovery, and more to address physical disability.
Fliar Intelligence Index™ 50how this company ranks against its industry peers
Funding
top 22%Product
top 28%News
top 30%Partners
top 31%Tech
top 40%Growth
top 47%Funding: Raised $132M across 13 rounds · 13 rounds over 15 yrs (0.9/yr) · Last round Post IPO (Mar 2026)
Product: 1 published app (39 installs) · Company stage: Public
News: 10 BI events in 12 mo (of 23 tracked, 6 types) · -9% YoY · 5 high-value events (IPO/M&A/funding/contracts) in 12 mo
Audience (LinkedIn): 3k LinkedIn followers — 2.2% of this cohort's audience
Activity (LinkedIn): 1 product launches · 1 partnerships (incl. Oramed Pharmaceuticals Inc.) announced in 12 mo
Funding rounds
- Mar 2026Post IPO$20M
- Jan 2025Post IPO$5M
- Feb 2021Post IPO$40M
- Dec 2020Post IPO$8M
Founders & team
Investors
Proseed Venture Capital Fund, Kreos Capital, Yaskawa, Shavit Capital
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform LaunchAkamai
#3
Series B · Boston, Massachusetts · founded 2016 · 46 employees$72.5Mraised▾
Series B · Boston, Massachusetts · founded 2016 · 46 employees
Miach Orthopaedics is developing bio-engineered surgical implants for connective tissue repair. The company has developed a BEAR implant which is a proprietary bio-engineered sponge designed as a bridging scaffold to facilitate healing of the torn ACL (anterior cruciate ligament).
Fliar Intelligence Index™ 64how this company ranks against its industry peers
Funding
top 23%Talent
top 28%Patents
top 32%Moat
top 32%Growth
top 35%Innovation
top 39%Funding: Raised $72.5M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) · Last round Series B (May 2026)
Talent: Analyst team rating 5/5 · 2 named leaders on record · 2 C-suite/founder profiles curated
Patents: 33 patents matched (strict assignee match) · 33 filings since 2022 vs 0 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 9k LinkedIn followers — 7.0% of this cohort's audience
Funding rounds
- May 2026Series B$6.5M
- Oct 2025Conventional Debt$7.5M
- Apr 2024Series B$20M
- Jan 2023Series B$30M
Founders & team
Investors
SVB, Sectoral, Endeavour Vision, Amzak Health, Smith+Nephew, NFLPA
Tech stack
CloudflareCloudflare Bot ManagementCore-JsCrazy EggFacebook PixelFancybox
#4
Public · Cambridge, Massachusetts · founded 2014 · 101 employees$92.5Mraised▾
Public · Cambridge, Massachusetts · founded 2014 · 101 employees
Developer of gene therapy platform for Duchenne muscular dystrophy. The lead candidate SGT-001 is Microdystrophin, a synthetic version of the dystrophin gene which stabilizes the muscle membrane and dystrophin-glycoprotein complex. Also, developed a soft wearable device for mobility and help preserve muscle function.
Fliar Intelligence Index™ 53how this company ranks against its industry peers
Patents
top 20%Funding
top 24%Innovation
top 31%Tech
top 33%Moat
top 38%News
top 48%Patents: 60 patents matched (strict assignee match) · 43 filings since 2022 vs 17 in 2017-21 · Latest publication 2026
Funding: Raised $92.5M across 7 rounds · 7 rounds over 11 yrs (0.6/yr) · Last round Post IPO (Mar 2026)
Innovation: 60 patents (top 27% of patent-holders) · 43 filings since 2022 vs 17 in 2017-21
Funding rounds
- Mar 2026Post IPO$240M
- Jan 2024Post IPO$108.9M
- Dec 2020Post IPO$90M
- Oct 2020Post IPO$40M
Investors
RA Capital Management, RTW Investments, Foresite Capital, Perceptive Advisors, Janus Henderson Investors, Biogen
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform LaunchAmazon Web Services
#5
Series C · Burlington, Massachusetts · founded 2023$51.7Mraised▾
Series C · Burlington, Massachusetts · founded 2023
Developer of biologic therapeutic engineered for orthopedic conditions treatment. The company focuses on developing a multi-protein therapeutic to target disease drivers. Its management team has experience in biologic drug development. The company's asset is for chronic lumbosacral radiculopathy.
Fliar Intelligence Index™ 35how this company ranks against its industry peers
Funding
top 28%Talent
bottom 49%Global
bottom 25%Funding: Raised $51.7M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) · Last round Series C (Mar 2026)
Talent: 1 named leader on record · 1 C-suite/founder profile curated
Global: Single-market focus (United States)
Audience (LinkedIn): 344 LinkedIn followers
Funding rounds
- Mar 2026Series C$34.8M
- Oct 2024Series B$16.8M
Founders & team
#6
Series A · Needham, Massachusetts · founded 2020 · 5 employees$5.6Mraised▾
Series A · Needham, Massachusetts · founded 2020 · 5 employees
Developer of gene therapies for a broad range of diseases. The company is developing a pipeline of a broad range of therapies for immune and age-related conditions which includes RMD 1101 for rheumatology, RMD 1202 for endocrinology, RMD 1501 for neurology, and RMD 1201 for Type-1 diabetes.
Fliar Intelligence Index™ 7how this company ranks against its industry peers
Funding
top 37%Moat
top 48%Global
bottom 36%Tech
bottom 22%Market
bottom 20%Funding: Raised $5.6M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) · Last round Series A (May 2026)
Moat: Editorial + unicorn rating 4/10 · 10 curated direct competitors tracked
Global: Investors from 2 countries beyond United States
Audience (LinkedIn): 3k LinkedIn followers — 2.3% of this cohort's audience
Hiring (LinkedIn): 7 hiring posts in 12 mo (public) · momentum -2 · hiring: Research Associate, Scientist/Senior Scientist, Molecular Biology
Activity (LinkedIn): 1 partnerships (incl. Lilly) announced in 12 mo
Funding rounds
- May 2026Series A$1.5M
- Sep 2024Seed—
- Aug 2023Grant (prize money)$275K
- Aug 2022Seed$2.3M
Investors
LifeSpan Vision Ventures, Sherwood Ventures, Longevitytech.fund, Primo Medical Group, Angel Star Ventures, APIS Health Angels
#7
Series B · Lowell, Massachusetts · founded 2014 · 29 employees$24.4Mraised▾
Series B · Lowell, Massachusetts · founded 2014 · 29 employees
Developer of synthetic adhesive used for bone/dental repair. The company's proprietary technology includes Tetranite that is a bio-engineered protein derived from worms. The company's product can be used in implant stabilization, fracture repair, spine fusion, dental bone grafting, joint reconstruction, and cranial flap fixation.
Fliar Intelligence Index™ 57how this company ranks against its industry peers
Talent
top 23%Innovation
top 28%Patents
top 28%Funding
top 34%Moat
top 38%Market
bottom 37%Talent: 5 named leaders on record · 5 C-suite/founder profiles curated
Innovation: 50 patents (top 31% of patent-holders) · 44 filings since 2022 vs 6 in 2017-21
Patents: 50 patents matched (strict assignee match) · 44 filings since 2022 vs 6 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 4k LinkedIn followers — 2.9% of this cohort's audience
Funding rounds
- May 2025Grant (prize money)$2M
- Sep 2024Grant (prize money)$1.7M
- Oct 2023Grant (prize money)—
- Sep 2023Grant (prize money)$3M
Founders & team
Investors
NIH, MassChallenge, University of Pittsburgh, Pacific Dental Services, HHS
#8
Series A · Boston, Massachusetts · founded 2025$8Mraised▾
Series A · Boston, Massachusetts · founded 2025
Developer of targeted small-molecule therapies for musculoskeletal health and bone regeneration. The company is focused on creating therapies that target areas of active bone loss. It aims to preserve the body’s natural bone remodeling process. The platform is designed to limit drug activity to specific sites. It follows a biomarker and imaging-friendly development path.
Fliar Intelligence Index™ 37how this company ranks against its industry peers
Talent
top 38%Funding
top 43%Global
bottom 33%Talent: 2 named leaders on record · 2 C-suite/founder profiles curated
Funding: Raised $8.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) · Last round Series A (Nov 2025)
Global: Single-market focus (United States)
Audience (LinkedIn): 652 LinkedIn followers
Activity (LinkedIn): 1 product launches announced in 12 mo
Funding rounds
- Nov 2025Series A$8M
Founders & team
Investors
Pillar VC, KdT Ventures, age1, Slocum Wealth Management
#9
Acquired · Holliston, Massachusetts · founded 2001 · 13 employees$16.2Mraised▾
Acquired · Holliston, Massachusetts · founded 2001 · 13 employees
Research and development for advanced prosthetic upper limb technology. The company is a research hub dedicated to developing high-risk/high-reward concepts and cutting-edge technologies in the field of prosthetics and rehabilitation. They focus on creating innovative human-machine interfaces and intuitive control technology for advanced prosthetic upper limbs. Their work aims to improve the quality of life for prosthesis users through clinically dedicated engineering. They actively recruit patients for research studies to advance available technology, demonstrating a commitment to social impact within the healthcare sector. The company's research contributes to the development of transformative technologies in the bionics field.
Fliar Intelligence Index™ 29how this company ranks against its industry peers
Product
top 26%Funding
top 30%Innovation
top 34%Tech
bottom 30%Global
bottom 29%Market
bottom 27%Product: 6 distinct product lines · Company stage: Acquired
Funding: Raised $16.2M across 19 rounds · 19 rounds over 17 yrs (1.1/yr) · Last round Grant (prize money) (May 2025)
Innovation: 6 product lines
Funding rounds
- May 2025Grant (prize money)$2M
- Apr 2025Grant (prize money)$599.1K
- Apr 2025Grant (prize money)$574.8K
- Apr 2025Grant (prize money)$100K
Investors
SBIR, NIH, HHS, Military Health
Tech stack
WordpressMysqlPhpTwenty SeventeenElementorContact Form 7
#10
Series A · Raynham, Massachusetts · founded 2016 · 9 employees$1.3Mraised▾
Series A · Raynham, Massachusetts · founded 2016 · 9 employees
Developer of implants for the treatment of spinal fractures
Fliar Intelligence Index™ 11how this company ranks against its industry peers
Funding
top 47%Talent
bottom 49%Global
bottom 29%Market
bottom 23%Funding: Raised $1.3M across 2 rounds · 2 rounds over 5 yrs (0.4/yr) · Last round Series A (Mar 2026)
Talent: 1 named leader on record · 1 C-suite/founder profile curated
Global: Single-market focus (United States)
Audience (LinkedIn): 2k LinkedIn followers
Activity (LinkedIn): 1 partnerships (incl. Evergen) announced in 12 mo
Funding rounds
- Mar 2026Series A$6M
- Dec 2023Series A—
- May 2021Seed$1.3M
Founders & team
Investors
Cherrystone Angel Group, Slater Technology Fund, Walnut Ventures, Beacon Angels, River Valley Investors, Xcellerant Ventures
#11
Series C · Billerica, Massachusetts · founded 1994 · 20 employees$47.3Mraised▾
Series C · Billerica, Massachusetts · founded 1994 · 20 employees
Developer of therapeutic devices for spine surgery. HydroCision intends to improve outcomes in spine surgery by providing fluidjet driven medical devices for use in open and minimally invasive spine procedures, to simultaneously cut, ablate, and remove hard and soft tissue quickly, safely, and effectively without the collateral thermal or mechanical trauma of other surgical modalities. Also, it allows enhanced visibility during the operation of the device, which is particularly important in spine procedures where the surgical site is surrounded by vital structures such as nerves and blood vessels.
Fliar Intelligence Index™ 57how this company ranks against its industry peers
Innovation
top 20%Patents
top 20%Funding
top 27%Moat
top 28%Growth
top 35%Product
top 35%Innovation: 113 patents (top 17% of patent-holders) · 32 filings since 2022 vs 13 in 2017-21 · 2 product lines
Patents: 113 patents matched (strict assignee match) · 32 filings since 2022 vs 13 in 2017-21 · Latest publication 2026
Funding: Raised $47.3M across 13 rounds · 13 rounds over 25 yrs (0.5/yr) · Last round Series C (Nov 2024)
Audience (LinkedIn): 3k LinkedIn followers — 2.1% of this cohort's audience
Activity (LinkedIn): 1 partnerships (incl. Orthopedic Performance Institute) announced in 12 mo
Funding rounds
- Nov 2024Series C$2.5M
- Apr 2023Grant (prize money)$300K
- Mar 2017Series C$3M
- Sep 2010Series C—
Investors
Triathlon Medical Ventures, Oxford Bioscience Partners, Rising Tide Fund, Zero Stage Capital, Volcano Capital Management, BioVentures Investors
Tech stack
CloudflareCloudflare Bot ManagementContact Form 7Core-JsEmbedplusFont Awesome
#12
Funding Raised · Boston, Massachusetts · founded 2016$9.7Mraised▾
Funding Raised · Boston, Massachusetts · founded 2016
Innovating muscle assessment technology for neuromuscular disorders and muscle wasting diseases. They are dedicated to building clinical gold standards for measuring muscle wasting and its treatment impact. The company develops comprehensive, painless, and portable solutions for assessing muscle quality, even at home. Their technology aims to aid in the diagnosis, prognosis, and treatment of neuromuscular and musculoskeletal diseases. They offer quantitative data on functional capability while the muscle remains at rest, using a portable, non-invasive device. Their electrical impedance myography (EIM) technology measures changes in electrical impedance to assess muscle composition and micro infrastructure. This technology has the potential to reduce clinical trial sample sizes, enable standardized data collection, and serve as a powerful biomarker. Their mission is to comprehensively assess and display changes in skeletal muscle composition and micro infrastructure, supporting clinicians, scientists, caregivers, and patients. The company's technology holds potential for early disease diagnosis and could replace expensive muscle measurement devices.
Fliar Intelligence Index™ 35how this company ranks against its industry peers
Moat
top 38%Funding
top 45%Talent
top 45%Patents
bottom 43%Innovation
bottom 36%Global
bottom 31%Moat: Editorial + unicorn rating 4/10 · IP moat: 8 patents
Funding: Raised $9.7M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) · Last round Grant (prize money) (May 2025)
Talent: 2 named leaders on record
Funding rounds
- May 2025Grant (prize money)$2M
- Jan 2025Grant (prize money)$1.7M
- Jun 2024Grant (prize money)$1M
- Aug 2022Grant (prize money)$1.8M
Founders & team
Investors
HHS, Caerus Ventures, Nautilus Venture Partners
Funding & investor landscape
$2.9Btotal disclosed funding
49companies funded
210disclosed rounds
2rounds last 90 days
Most active investors
Notable founders
Siddhartha Mukherjee
Founder · Vor Biopharma
Robert Ang
President and CEO · Vor Biopharma
Larry Jasinski
CEO & MD · Lifeward
Martha Murray
Founder · Miach Orthopaedics
Patrick McBrayer
President & CEO · Miach Orthopaedics
Andrew Hall
CEO · Consano Bio
Michael Brown
Co-Founder · RevBio
Brian Hess
Co-Founder & CEO · RevBio
Benton Swanson
Co-Founder & CEO · Skeletalis
Colin Greineder
Co-Founder · Skeletalis
Dom Messerli
CEO & President · Lenoss Medical
Jerry Panos
CEO · Myolex
Prism market signals · United States · country-scoped Prism corpus, 517,506 docs
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth flat
RESEARCH IN MASSACHUSETTS · Health & Bio
How research on Medical Devices in Massachusetts is moving
A read on the academic research around Medical Devices in Massachusetts — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 49 papers.
49 papers · stance +0.14 · 28% breakthrough · 56% concern
top institutions
- Massachusetts General Hospital24
- Massachusetts Institute of Technology13
- University of Massachusetts Amherst5
- Massachusetts Eye and Ear Infirmary5
- Massachusetts School of Law2
leading researchers
Joseph S. Ross · Sanket S. Dhruva · Julian M. Goldman · Vinay K. Rathi · Aurélien vander Straeten · Baburaj, Abiram
prism intelligence · tone & topics
84% positive · 4% critical tone
HealthcareHealthBusinessMedical TechnologyMedicinePharmaceuticals
▲
Breakthroughs11 · 22%
▲ 15%→28% share
▲1.9× share momentum2 median citations73% since 2021mostly methods-led
Breakthroughs are rising (15%→28% of field), led by Robot.
rising sub-themes (early→recent)
- Robot3
- In vivo2
- Nanotechnology2
- Compromise2
- Medical record2
Landmark Single-Site Colectomy With Miniature In Vivo Robotic Platform · 37 cites
◆
Advancements6 · 12%
▼ 23%→7% share
▼0.3× share momentum7 median citations33% since 2021mostly empirical
Advancements are cooling (23%→7% of field), led by Biomedical engineering.
rising sub-themes (early→recent)
- Biomedical engineering2
- Robot2
- Heart failure1
- Intensive care medicine1
- Cardiology1
Landmark Force control of flexible catheter robots for beating heart surgery · 67 cites
▼
Concerns22 · 45%
▲ 46%→48% share
▲1.0× share momentum5 median citations64% since 2021mostly position pieces
Concerns are rising (46%→48% of field), led by Food and drug administration.
rising sub-themes (early→recent)
- Food and drug administration1→3
Newly emergingRisk analysis (engineering) 0→4
Landmark The FDA approval process for medical devices: an inherently flawed system or a valuable pathway for innovation? · 89 cites
Common questions
How many Orthopedics companies are there in Massachusetts, United States?
Radar tracks 76 indexable Orthopedics companies headquartered in Massachusetts, United States that meet our profile-completeness bar.
What is the total funding raised by Orthopedics companies in Massachusetts, United States?
The Orthopedics companies in Massachusetts, United States on this list have raised a combined $2.9B in disclosed equity funding across 49 funded companies.
Which is the highest-funded Orthopedics company in Massachusetts, United States?
Vor Biopharma is the highest-funded Orthopedics company in Massachusetts, United States, with $477.1M in disclosed equity funding.
How many Orthopedics companies in Massachusetts, United States are funded?
49 of the 76 Orthopedics companies in Massachusetts, United States on this list have disclosed at least one equity funding round.
How many Orthopedics unicorns are there in Massachusetts, United States?
None of the Orthopedics companies in Massachusetts, United States on this list currently has a disclosed valuation of $1B or more.
Who are the top investors in Massachusetts, United States Orthopedics companies?
The most active investors in Massachusetts, United States Orthopedics companies on this list include HHS, MassChallenge, DSM, Greenspring Associates, JLABS.
Riya SenguptaFinancials
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.