Radar · Orthopedics in United States
Best Orthopedics Companies in United States
The 1157 best Orthopedics companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Biosplice.
By Riya SenguptaFinancials
1157companies tracked
$15.6Bdisclosed funding
1unicorns
478have raised
Ranking the top Orthopedics companies in the United States by disclosed equity funding and recent funding momentum, this directory covers 1,157 tracked ventures with $15.6B in total disclosed capital behind them. The real money story, though, is in earned revenue. Across 13 validated filers, the combined revenue pool hits $4.1B, with a median company pulling $132M at roughly 6% YoY growth. Globus Medical leads on profitability at $124M net income, 20x the sector median, while Bone Biologics Corp booked $1.1B in revenue. Those aren't funding rounds. That's operating scale. And against a global orthopedics market of ~$23.4B, driven by aging populations and rising surgical volumes, you can see why the revenue pool here is still only a fraction of what's available.
So what's driving the funding? One signal worth tracking: minimally invasive orthopedic surgery has already minted at least one billionaire in this space. The hot facility themes, orthopedic surgery centers, specialty hospitals, bone and joint care, point toward where capital is concentrating. I'd watch Globus Medical's 27% revenue growth as the clearest leading indicator in the filer set.
Sources & further reading
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FLIAR INTELLIGENCE · ORTHOPEDICS × UNITED STATES
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
50companies analysed
82%cloud-native stacks
2025funding peak (by rounds)
2015median founding year
40median Fliar Index™
199kcombined LinkedIn audience
24%of audience held by top 3
5companies hiring publicly (12 mo)
Ranked: Best Orthopedics companies in United States
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Market signals (1y) | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Vor Biopharma Developer of therapeutics to treat acute myeloid leukemia 78Funding top 12%Patents top 19%Innovation top 20%News top 24% All 10 signals ▾Fundingtop 12% Patentstop 19% Innovationtop 20% Newstop 24% Talenttop 27% Moattop 35% Growthtop 39% Techtop 40% Markettop 47% Globalbottom 40% Funding: Raised $477M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) Patents: 188 patents matched (strict assignee match) · 154 filings since 2022 vs 34 in 2017-21 rank vs industry peers · Fliar Intelligence Index 78/100 | $477M | 6 mo ago | 133 | Siddhartha Mukherjee Founder | WordPressApple iCloud MailMySQL+29 | 29 signals ▲262% Leadership · Earnings · Funding | 188 patents Patents concentrated in health & consumer products | — |
| 2 | Quince Therapeutics Developer of therapeutics for orthopedic diseases 53Funding top 13%Growth top 37%Tech top 44%Moat top 48% All 8 signals ▾Fundingtop 13% Growthtop 37% Techtop 44% Moattop 48% Talentbottom 49% Marketbottom 37% Newsbottom 37% Globalbottom 37% Funding: Raised $420M across 7 rounds · 7 rounds over 12 yrs (0.6/yr) Growth: Web rank 50,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $420M | 1 mo ago | 21 | Dirk Thye CEO | DrupalPHPZURB Foundation+20 | — | — | — |
| 3 | Moximed Developer of an implant for pre-arthroplasty osteoarthritis patients 53Funding top 18%Moat top 19%Product top 26%Patents top 31% All 11 signals ▾Fundingtop 18% Moattop 19% Producttop 26% Patentstop 31% Innovationtop 34% Growthtop 35% Techbottom 49% Talentbottom 49% Globalbottom 44% Marketbottom 26% Newsbottom 18% Funding: Raised $262M across 7 rounds · 7 rounds over 18 yrs (0.4/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 271 patents rank vs industry peers · Fliar Intelligence Index 53/100 | $262M | 22 mo ago | 15 | Josh Makower Founder & Chairman | WordPressApple iCloud MailMicrosoft 365+20 | — | 271 patents Implantable orthopedic devices for joint load reduction and mechanical energy absorption | — |
| 4 | SetPoint Medical Developer of implantable neuromodulation devices for inflammatory diseases 72Funding top 18%Product top 18%Innovation top 19%Patents top 22% All 10 signals ▾Fundingtop 18% Producttop 18% Innovationtop 19% Patentstop 22% Growthtop 24% Newstop 24% Moattop 26% Techtop 49% Globalbottom 42% Marketbottom 40% Funding: Raised $248M across 11 rounds · 11 rounds over 17 yrs (0.6/yr) Product: 8 distinct product lines · Company stage: Series F rank vs industry peers · Fliar Intelligence Index 72/100 | $248M | 14 mo ago | 46 | — | WordPressApple iCloud MailMicrosoft 365+20 | 8 signals Funding | 157 patents Bioelectronic neuromodulation devices targeting vagus nerve for chronic inflammation control | 1 launch · 1 partnership |
| 5 | Rani Therapeutics Developer of technology for the oral delivery of large drug molecules 72Growth top 22%Funding top 23%Patents top 24%Talent top 27% All 11 signals ▾Growthtop 22% Fundingtop 23% Patentstop 24% Talenttop 27% Innovationtop 28% Newstop 30% Moattop 35% Techtop 45% Marketbottom 49% Fin. healthbottom 44% Globalbottom 42% Growth: Revenue +59% YoY · Fresh capital in last 24 mo Funding: Raised $234M across 6 rounds · 6 rounds over 13 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 72/100 | $234M | 7 mo ago | 163 | Mir Imran Founder | DrupalPHPZURB Foundation+25 | 16 signals ▲167% Leadership · Earnings · Funding | 456 patents Oral ingestible devices for delivering biologic therapeutics to the gastrointestinal tract | 1 launch |
| 6 | Centinel Spine Developer of spinal devices to treat degenerative disc disease 48Funding top 21%Moat top 21%Patents top 35%Innovation top 40% All 11 signals ▾Fundingtop 21% Moattop 21% Patentstop 35% Innovationtop 40% Producttop 40% Talentbottom 49% Growthbottom 47% Marketbottom 46% Techbottom 38% Globalbottom 37% Newsbottom 24% Funding: Raised $176M across 4 rounds · 4 rounds over 9 yrs (0.4/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 96 patents rank vs industry peers · Fliar Intelligence Index 48/100 | $176M | 15 mo ago | 130 | Steven Murray CEO | SalesforceVimeoBootstrap+12 | — | 96 patents Spinal intervertebral fixation implants with tissue‑sparing insertion mechanisms | 1 partnership |
| 7 | Angitia Developer of drugs for muscle, bone, and joint diseases 29Funding top 16%Talent top 38%Moat top 47%Market bottom 40% All 7 signals ▾Fundingtop 16% Talenttop 38% Moattop 47% Marketbottom 40% Globalbottom 39% Innovationbottom 23% Patentsbottom 20% Funding: Raised $156M across 5 rounds · 5 rounds over 6 yrs (0.8/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 29/100 | $156M | 4 mo ago | — | Muyu Li Co-Founder & COO | — | — | 4 patents Anti‑sclerostin biologics for osteoporosis and bone‑mass therapies | — |
| 8 | Lifeward Developer of exoskeletons for individuals with spinal cord injuries and stroke rehabilitation 50Funding top 22%Product top 28%News top 30%Partners top 31% All 13 signals ▾Fundingtop 22% Producttop 28% Newstop 30% Partnerstop 31% Techtop 40% Growthtop 47% Moattop 47% Markettop 48% Patentstop 50% Talentbottom 49% Innovationbottom 48% Fin. healthbottom 40% Globalbottom 39% Funding: Raised $132M across 13 rounds · 13 rounds over 15 yrs (0.9/yr) Product: 1 published app (39 installs) · Company stage: Public rank vs industry peers · Fliar Intelligence Index 50/100 | $132M | 2 mo ago | — | Larry Jasinski CEO & MD | WordPressMySQLPHP+31 | 10 signals Earnings · Contracts · M&A | 3 patents Pressure‑based anti‑gravity exercise and rehabilitation equipment for user weight support | 1 launch |
| 9 | Osteal Therapeutics Developer of pharmaceuticals for musculoskeletal therapeutics to treat orthopedic infections 29Funding top 19%Moat top 38%Talent bottom 49%Global bottom 37% All 5 signals ▾Fundingtop 19% Moattop 38% Talentbottom 49% Globalbottom 37% Marketbottom 31% Funding: Raised $111M across 7 rounds · 7 rounds over 8 yrs (0.9/yr) Moat: Editorial + unicorn rating 5/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 29/100 | $111M | 8 mo ago | 13 | David Thompson Chairman and Chief Executive Officer | — | — | — | 9 job openings |
| 10 | Allay Therapeutics Developer of drugs for post-surgical pain management 42Funding top 18%Moat top 39%Market bottom 44%Global bottom 38% All 5 signals ▾Fundingtop 18% Moattop 39% Marketbottom 44% Globalbottom 38% Newsbottom 21% Funding: Raised $102M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) Moat: Editorial + unicorn rating 7/10 · 10 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 42/100 | $102M | 12 mo ago | 50 | — | — | — | — | — |
| 11 | Solid Biosciences Developer of gene therapy platform for Duchenne muscular dystrophy 53Patents top 20%Funding top 24%Innovation top 31%Tech top 33% All 10 signals ▾Patentstop 20% Fundingtop 24% Innovationtop 31% Techtop 33% Moattop 38% Newstop 48% Marketbottom 49% Growthbottom 44% Globalbottom 42% Fin. healthbottom 32% Patents: 60 patents matched (strict assignee match) · 43 filings since 2022 vs 17 in 2017-21 Funding: Raised $92.5M across 7 rounds · 7 rounds over 11 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 53/100 | $92M | 3 mo ago | 101 | — | WordPressApple iCloud MailMySQL+22 | 4 signals ▼33% Earnings · Funding · Leadership | 60 patents AAV vector manufacturing and formulation for cardiac gene therapies | — |
| 12 | Shoulder Innovations Provider of total shoulder replacement solutions based on glenoid technology 72Funding top 18%Patents top 20%Innovation top 22%Product top 24% All 12 signals ▾Fundingtop 18% Patentstop 20% Innovationtop 22% Producttop 24% Growthtop 25% Newstop 27% Moattop 29% Techtop 35% Talenttop 35% Fin. healthbottom 46% Marketbottom 42% Globalbottom 40% Funding: Raised $79.2M across 13 rounds · 13 rounds over 15 yrs (0.9/yr) Patents: 116 patents matched (strict assignee match) · 65 filings since 2022 vs 32 in 2017-21 rank vs industry peers · Fliar Intelligence Index 72/100 | $79M | 10 mo ago | 30 | Stephen Gunther Founder | WordPressTypeScriptPHP+29 | 19 signals ▲280% Earnings · IPO · Leadership | 116 patents Convertible shoulder arthroplasty implants and customizable surgical instrumentation for orthopedic surgery | 1 job opening · 2 launchs |
| 13 | Miach Orthopaedics Developer of surgical implants for connective tissue repair 64Funding top 23%Talent top 28%Patents top 32%Moat top 32% All 10 signals ▾Fundingtop 23% Talenttop 28% Patentstop 32% Moattop 32% Growthtop 35% Innovationtop 39% Techtop 48% Marketbottom 46% Globalbottom 42% Newsbottom 22% Funding: Raised $72.5M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) Talent: Analyst team rating 5/5 · 2 named leaders on record rank vs industry peers · Fliar Intelligence Index 64/100 | $72M | 1 mo ago | 46 | Martha Murray Founder | WordPressMySQLPHP+21 | — | 33 patents Injectable collagen biomaterials for orthopedic tissue repair and regeneration | — |
| 14 | Onkos Surgical Modular segmental solutions (3D printing) for orthopedic procedures 48Funding top 23%Talent top 38%Moat top 43%Innovation top 47% All 9 signals ▾Fundingtop 23% Talenttop 38% Moattop 43% Innovationtop 47% Techtop 47% Patentstop 47% Marketbottom 40% Globalbottom 36% Newsbottom 21% Funding: Raised $72.3M across 5 rounds · 5 rounds over 11 yrs (0.5/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 48/100 | $72M | 17 mo ago | 77 | Patrick Treacy Co-Founder & CEO | WordPressMySQLPHP+28 | — | 42 patents Soft-tissue attachment technologies for orthopedic implants and endoprostheses. | — |
| 15 | Epicrispr Bio Developer of therapeutics for multiple disease 35Funding top 23%Talent top 38%Moat top 42%Tech bottom 43% All 6 signals ▾Fundingtop 23% Talenttop 38% Moattop 42% Techbottom 43% Globalbottom 37% Marketbottom 32% Funding: Raised $68.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 35/100 | $68M | 14 mo ago | — | Lei Qi Founder | WordPressMySQLPHP+21 | — | — | — |
| 16 | MiRus Developer of rhenium-based implants for spine surgeries 60Patents top 11%Innovation top 12%Funding top 21%Moat top 26% All 10 signals ▾Patentstop 11% Innovationtop 12% Fundingtop 21% Moattop 26% Producttop 30% Marketbottom 44% Growthbottom 44% Techbottom 44% Globalbottom 38% Newsbottom 27% Patents: 288 patents matched (strict assignee match) · 190 filings since 2022 vs 82 in 2017-21 Innovation: 288 patents (top 8% of patent-holders) · 190 filings since 2022 vs 82 in 2017-21 rank vs industry peers · Fliar Intelligence Index 60/100 | $65M | 1 mo ago | 94 94 → 135 (+44%) | — | WordPressMySQLPHP+22 | — | 288 patents Medical implant alloys, coatings, and delivery accessories for cardiovascular and orthopedic devices | — |
| 17 | Consano Bio Developer of biologic therapeutic engineered for orthopedic conditions treatment 35Funding top 28%Talent bottom 49%Global bottom 25% All 3 signals ▾Fundingtop 28% Talentbottom 49% Globalbottom 25% Funding: Raised $51.7M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 35/100 | $52M | 3 mo ago | — | Andrew Hall CEO | — | — | — | — |
| 18 | ClearFlow Provider of an anti-clogging platform for surgical drainage devices 48Funding top 24%Moat top 28%Patents top 30%Growth top 35% All 11 signals ▾Fundingtop 24% Moattop 28% Patentstop 30% Growthtop 35% Talenttop 38% Innovationtop 42% Producttop 43% Techtop 47% Globalbottom 40% Marketbottom 23% Newsbottom 21% Funding: Raised $50.6M across 14 rounds · 14 rounds over 17 yrs (0.8/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 91 patents rank vs industry peers · Fliar Intelligence Index 48/100 | $51M | 10 mo ago | 10 10 → 25 (+150%) | Edward Boyle Founder | Cart FunctionalityWordPressMySQL+22 | — | 91 patents Medical tube and catheter obstruction removal systems with guide‑wire actuation | 2 launchs |
| 19 | Catalyst OrthoScience A total shoulder implant solution 60Funding top 20%Growth top 28%Patents top 28%Product top 31% All 11 signals ▾Fundingtop 20% Growthtop 28% Patentstop 28% Producttop 31% Techtop 32% Moattop 32% Innovationtop 36% Partnerstop 45% Globalbottom 36% Marketbottom 29% Newsbottom 18% Funding: Raised $50.1M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 60/100 | $50M | 7 mo ago | 17 | — | WordPressMySQLPHP+26 | — | 71 patents Patents concentrated in health & consumer products | 1 job opening |
| 20 | Juvena Therapeutics Company developing protein based therapies for sarcopenia and muscle regeneration 29Funding top 25%Moat top 31%Talent top 38%News bottom 42% All 7 signals ▾Fundingtop 25% Moattop 31% Talenttop 38% Newsbottom 42% Globalbottom 39% Marketbottom 34% Techbottom 28% Funding: Raised $50.0M across 4 rounds · 4 rounds over 8 yrs (0.5/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 29/100 | $50M | 11 mo ago | 30 | Jeremy O'Connell Co-Founder & CSO | WordPressMySQLPHP+16 | — | — | — |
| 21 | HydroCision Developer of therapeutic devices for spine surgery 57Innovation top 20%Patents top 20%Funding top 27%Moat top 28% All 9 signals ▾Innovationtop 20% Patentstop 20% Fundingtop 27% Moattop 28% Growthtop 35% Producttop 35% Techtop 49% Globalbottom 36% Marketbottom 28% Innovation: 113 patents (top 17% of patent-holders) · 32 filings since 2022 vs 13 in 2017-21 Patents: 113 patents matched (strict assignee match) · 32 filings since 2022 vs 13 in 2017-21 rank vs industry peers · Fliar Intelligence Index 57/100 | $47M | 19 mo ago | 20 20 → 34 (+70%) | — | WordPressMySQLPHP+26 | — | 113 patents Patents concentrated in health & consumer products | 1 partnership |
| 22 | OXOS Medical Developer of orthopedic imaging devices and software 57Funding top 24%Growth top 28%Tech top 43%Product top 47% All 8 signals ▾Fundingtop 24% Growthtop 28% Techtop 43% Producttop 47% Moattop 48% Talentbottom 49% Marketbottom 45% Globalbottom 29% Funding: Raised $45.0M across 9 rounds · 9 rounds over 5 yrs (1.8/yr) Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 57/100 | $45M | 6 mo ago | 77 | Evan Ruff CEO | WordPressApple iCloud MailGoogle Workspace+31 | — | — | 1 launch · 1 partnership |
| 23 | Epibone Developer of patient‑specific bone and cartilage grafts 50Moat top 25%Talent top 28%Funding top 29%Patents top 32% All 9 signals ▾Moattop 25% Talenttop 28% Fundingtop 29% Patentstop 32% Innovationtop 38% Techtop 46% Globalbottom 42% Marketbottom 31% Newsbottom 21% Moat: Editorial + unicorn rating 7/10 · IP moat: 48 patents Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 50/100 | $44M | 9 mo ago | 34 | Elisa Cimetta Co-Founder | Cart FunctionalitySquarespace CommerceSquarespace+12 | — | 48 patents Regenerative orthopedic biomaterials for injectable cartilage/tendon/ligament repair and surgical tools. | — |
| 24 | Infinite Biomedical Innovative upper limb myoelectric solutions improving lives through advanced technology 48Growth top 35%Funding top 38%Innovation top 39%AI top 45% All 8 signals ▾Growthtop 35% Fundingtop 38% Innovationtop 39% AItop 45% Techtop 46% Producttop 46% Globalbottom 32% Marketbottom 21% Growth: Fresh capital in last 24 mo Funding: Raised $42.3M across 18 rounds · 18 rounds over 28 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $42M | 12 mo ago | 11 | — | Cart FunctionalityWix eCommerceWix+18 | — | — | 1 job opening · 1 launch |
| 25 | Immunis Developer of cell therapies for age-related and disease-related immune deficits 32Patents top 24%Innovation top 28%Moat top 32%Funding top 39% All 6 signals ▾Patentstop 24% Innovationtop 28% Moattop 32% Fundingtop 39% Globalbottom 40% Marketbottom 21% Patents: 48 patents matched (strict assignee match) · 45 filings since 2022 vs 3 in 2017-21 Innovation: 48 patents (top 32% of patent-holders) · 45 filings since 2022 vs 3 in 2017-21 rank vs industry peers · Fliar Intelligence Index 32/100 | $30M | 17 mo ago | 3 | — | — | — | 48 patents Prostate cancer liquid biopsy diagnostics using secretome-derived biomarkers | 1 launch |
| 26 | Point Designs Provider of prosthetic fingers and partial hand prostheses 48Moat top 32%Innovation top 33%Funding top 35%Growth top 35% All 9 signals ▾Moattop 32% Innovationtop 33% Fundingtop 35% Growthtop 35% Patentstop 38% Talenttop 45% Techbottom 40% Globalbottom 31% Marketbottom 22% Moat: Editorial + unicorn rating 4/10 · IP moat: 22 patents Innovation: 22 patents (top 49% of patent-holders) · 17 filings since 2022 vs 5 in 2017-21 rank vs industry peers · Fliar Intelligence Index 48/100 | $27M | 14 mo ago | — | Stephen Huddle Co-Founder | HubSpot CMS HubAmazon Web ServicesHubSpot+11 | — | 22 patents Powered prosthetic hand components and actuation mechanisms for finger and thumb movement | — |
| 27 | RevBio Developer of synthetic adhesive used for bone/dental repair 57Talent top 23%Innovation top 28%Patents top 28%Funding top 34% All 7 signals ▾Talenttop 23% Innovationtop 28% Patentstop 28% Fundingtop 34% Moattop 38% Marketbottom 37% Globalbottom 31% Talent: 5 named leaders on record · 5 C-suite/founder profiles curated Innovation: 50 patents (top 31% of patent-holders) · 44 filings since 2022 vs 6 in 2017-21 rank vs industry peers · Fliar Intelligence Index 57/100 | $24M | 12 mo ago | 29 | Michael Brown Co-Founder | — | — | 50 patents Biomedical adhesives and bone fixation devices for controlled drug delivery | — |
| 28 | CytexOrtho Developer of bio-artificial devices to treat musculoskeletal diseases 32Funding top 38%Talent top 38%Growth top 41%Fin. health bottom 45% All 7 signals ▾Fundingtop 38% Talenttop 38% Growthtop 41% Fin. healthbottom 45% Techbottom 41% Globalbottom 32% Marketbottom 24% Funding: Raised $24.4M across 17 rounds · 17 rounds over 4 yrs (4.2/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 32/100 | $24M | 14 mo ago | 10 | Frank Moutos Co-Founder | WordPressMySQLPHP+16 | — | — | — |
| 29 | BioRestorative Therapies Developer of stem cell therapies to address multiple diseases 27News top 24%Moat top 32%Funding top 33%Patents top 42% All 11 signals ▾Newstop 24% Moattop 32% Fundingtop 33% Patentstop 42% Growthtop 43% Techtop 45% Innovationbottom 48% Globalbottom 41% Talentbottom 40% Fin. healthbottom 26% Marketbottom 21% News: 9 BI events in 12 mo (of 27 tracked, 6 types) · +80% YoY Moat: Editorial + unicorn rating 4/10 · IP moat: 45 patents rank vs industry peers · Fliar Intelligence Index 27/100 | $20M | 8 mo ago | 10 10 → 21 (+110%) | Lance Alstodt Chairman and CEO | WordPressMySQLPHP+25 | 9 signals ▲80% Funding · Earnings · Leadership | 45 patents Patents concentrated in chemistry & materials | — |
| 30 | Osteoboost Provider of a wearable medical device that utilizes targeted mechanical stimulation to deliver patented… 67Tech top 17%Talent top 28%Funding top 34%Growth top 35% All 6 signals ▾Techtop 17% Talenttop 28% Fundingtop 34% Growthtop 35% Globalbottom 48% Marketbottom 40% Tech: 49 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 67/100 | $19M | 2 mo ago | — | Nikhil Viswanathan Founder | WordPressMySQLPHP+25 | — | — | — |
| 31 | Liberating Technologies Research and development for advanced prosthetic upper limb technology 29Product top 26%Funding top 30%Innovation top 34%Tech bottom 30% All 6 signals ▾Producttop 26% Fundingtop 30% Innovationtop 34% Techbottom 30% Globalbottom 29% Marketbottom 27% Product: 6 distinct product lines · Company stage: Acquired Funding: Raised $16.2M across 19 rounds · 19 rounds over 17 yrs (1.1/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $16M | 12 mo ago | 13 | — | — | — | — | — |
| 32 | SelectION Provider of screening and development platform for drugs 11Funding top 36%Talent bottom 49%Global bottom 37%Market bottom 17% All 4 signals ▾Fundingtop 36% Talentbottom 49% Globalbottom 37% Marketbottom 17% Funding: Raised $15.9M across 3 rounds · 3 rounds over 7 yrs (0.4/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 11/100 | $16M | 9 mo ago | 2 | Andreas Klostermann Founder & CSO | — | — | — | — |
| 33 | Edge Surgical Provider of digital depth gauge for the measurement of bones 27Moat top 32%Funding top 36%Patents top 38%Innovation top 42% All 8 signals ▾Moattop 32% Fundingtop 36% Patentstop 38% Innovationtop 42% Producttop 46% Techbottom 47% Globalbottom 40% Marketbottom 22% Moat: Editorial + unicorn rating 7/10 · IP moat: 71 patents Funding: Raised $14.4M across 10 rounds · 10 rounds over 10 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 27/100 | $14M | 13 mo ago | 8 | — | WordPress Site EditorWordPressMySQL+21 | — | 71 patents Precision depth-sensing surgical tools and robot-assisted handheld medical devices | — |
| 34 | 4WEB Medical Innovative orthopedic implant company focused on advanced structural design and fusion 40Funding top 39%Growth top 45%Tech top 46%Talent bottom 49% All 8 signals ▾Fundingtop 39% Growthtop 45% Techtop 46% Talentbottom 49% Productbottom 48% Marketbottom 41% Globalbottom 29% Newsbottom 22% Funding: Raised $12.5M across 5 rounds · 5 rounds over 13 yrs (0.4/yr) Growth: Web rank 10,000,000 → 50,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 40/100 | $12M | 14 mo ago | 49 | Jessee Hunt Founder & CEO | WordPressApple iCloud MailMySQL+25 | — | — | 1 internship · 5 launchs |
| 35 | Accelus Provider of spine surgery robot systems for healthcare industries 45Talent top 28%Funding top 32%Moat top 39%Growth top 48% All 8 signals ▾Talenttop 28% Fundingtop 32% Moattop 39% Growthtop 48% Techbottom 43% Marketbottom 42% Globalbottom 37% Newsbottom 21% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $12.0M across 4 rounds · 4 rounds over 4 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 45/100 | $12M | 13 mo ago | 101 | Alex Lukianov Co-Founder & Chairman | WordPressMySQLPHP+25 | — | — | — |
| 36 | Tenon Medical Developer of therapy devices for sacroiliac joint dysfunction 40Funding top 33%Growth top 33%News top 35%Tech bottom 49% All 8 signals ▾Fundingtop 33% Growthtop 33% Newstop 35% Techbottom 49% Talentbottom 49% Fin. healthbottom 45% Marketbottom 32% Globalbottom 30% Funding: Raised $11.3M across 5 rounds · 5 rounds over 3 yrs (1.7/yr) Growth: Revenue +20% YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 40/100 | $11M | 3 mo ago | 22 22 → 32 (+45%) | Richard Ginn Founder | WordPressApple iCloud MailMicrosoft 365+18 | 9 signals Earnings · Funding | — | 1 launch |
| 37 | Myolex Innovating muscle assessment technology for neuromuscular disorders and muscle wasting diseases 35Moat top 38%Funding top 45%Talent top 45%Patents bottom 43% All 6 signals ▾Moattop 38% Fundingtop 45% Talenttop 45% Patentsbottom 43% Innovationbottom 36% Globalbottom 31% Moat: Editorial + unicorn rating 4/10 · IP moat: 8 patents Funding: Raised $9.7M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 35/100 | $10M | 13 mo ago | — | Jerry Panos CEO | — | — | 8 patents Electrical impedance myography sensors for quantitative muscle tissue assessment | — |
| 38 | Skeletalis Developer of targeted small-molecule therapies for musculoskeletal health and bone regeneration 37Talent top 38%Funding top 43%Global bottom 33% All 3 signals ▾Talenttop 38% Fundingtop 43% Globalbottom 33% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $8.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 37/100 | $8M | 7 mo ago | — | Benton Swanson Co-Founder & CEO | — | — | — | — |
| 39 | MuscleSound Point-of-care software for malnutrition assessment and improved patient care 14Moat top 25%Innovation top 46%Patents top 48%Product top 48% All 9 signals ▾Moattop 25% Innovationtop 46% Patentstop 48% Producttop 48% Fundingtop 49% Talentbottom 49% Globalbottom 37% Techbottom 21% Marketbottom 20% Moat: Editorial + unicorn rating 6/10 · IP moat: 34 patents Innovation: 34 patents (top 39% of patent-holders) · 11 filings since 2022 vs 16 in 2017-21 rank vs industry peers · Fliar Intelligence Index 14/100 | $8M | 7 mo ago | 6 | Stephen Kurtz Chairman & CEO | — | — | 34 patents Non‑invasive muscle metabolic and architectural assessment for fitness and medical monitoring | — |
| 40 | Elixirgen Therapeutics Developer of RNA therapeutics to treat multiple diseases 9Funding top 37%Talent bottom 49%Global bottom 37%Market bottom 21% All 5 signals ▾Fundingtop 37% Talentbottom 49% Globalbottom 37% Marketbottom 21% Techbottom 18% Funding: Raised $7.3M across 11 rounds · 11 rounds over 14 yrs (0.8/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 9/100 | $7M | 7 mo ago | 11 11 → 13 (+18%) | Minoru Ko Co-Founder | WordPressMySQLPHP+11 | — | — | — |
| 41 | Advanced Tactile Imaging Innovating women's pelvic healthcare with biomechanical mapping and digital twin technologies 16Innovation top 40%Funding top 43%Talent bottom 45%Product bottom 44% All 7 signals ▾Innovationtop 40% Fundingtop 43% Talentbottom 45% Productbottom 44% Globalbottom 29% Techbottom 24% Marketbottom 13% Innovation: 2 product lines Funding: Raised $6.3M across 8 rounds · 8 rounds over 10 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 16/100 | $6M | 10 mo ago | 6 | Vladimir Egorov Chairman and Chief Executive Officer | — | — | — | — |
| 42 | Nanochon Developer of 3D-printed implants for treating joint injuries 27Talent top 38%Funding top 40%Moat top 42%Tech top 49% All 8 signals ▾Talenttop 38% Fundingtop 40% Moattop 42% Techtop 49% Innovationtop 50% Patentsbottom 40% Globalbottom 29% Marketbottom 22% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $6.0M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 27/100 | $6M | 5 mo ago | 9 | Nathan Castro Co-Founder and CTO | WordPressMySQLPHP+23 | — | 11 patents Patents concentrated in health & consumer products | — |
| 43 | Remedium Bio Developer of gene therapies for a broad range of diseases 7Funding top 37%Moat top 48%Global bottom 36%Tech bottom 22% All 5 signals ▾Fundingtop 37% Moattop 48% Globalbottom 36% Techbottom 22% Marketbottom 20% Funding: Raised $5.6M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) Moat: Editorial + unicorn rating 4/10 · 10 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 7/100 | $6M | 1 mo ago | 5 | — | Google MapsBootstrapNginx+6 | — | — | 1 job opening |
| 44 | Blue Arbor Technologies Provider of prosthetic rehabilitation after limb loss 22Talent top 38%Funding bottom 48%Market bottom 37%Global bottom 25% All 4 signals ▾Talenttop 38% Fundingbottom 48% Marketbottom 37% Globalbottom 25% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $5.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 22/100 | $5M | 3 mo ago | — | Alex Vaskov Co-Founder & CTO | — | — | — | — |
| 45 | Mercury Bio Developer of nanoparticle-based drug delivery systems 8Funding top 50%Talent bottom 49%Global bottom 25%News bottom 22% All 5 signals ▾Fundingtop 50% Talentbottom 49% Globalbottom 25% Newsbottom 22% Marketbottom 20% Funding: Raised $3.5M across 5 rounds · 5 rounds over 4 yrs (1.2/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 8/100 | $4M | 8 mo ago | 6 | Bruce McCormick CEO | — | — | — | — |
| 46 | MyoGene Bio Manufacturer of devices for muscular dystrophy treatment 8Talent top 38%Funding top 45%Global bottom 29%Market bottom 10% All 4 signals ▾Talenttop 38% Fundingtop 45% Globalbottom 29% Marketbottom 10% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $3.2M across 6 rounds · 6 rounds over 5 yrs (1.2/yr) rank vs industry peers · Fliar Intelligence Index 8/100 | $3M | 7 mo ago | 3 | April Pyle Co-Founder | — | — | — | — |
| 47 | Waypoint Orthopedics Provider of decision support solutions for orthopedic surgery 10Talent top 38%Funding bottom 46%Global bottom 37%Market bottom 17% All 4 signals ▾Talenttop 38% Fundingbottom 46% Globalbottom 37% Marketbottom 17% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $3.0M across 8 rounds · 8 rounds over 5 yrs (1.6/yr) rank vs industry peers · Fliar Intelligence Index 10/100 | $3M | 3 mo ago | 2 | Stephen Banco Founder | — | — | — | — |
| 48 | Toetal Solutions Provider of the platform that offers solutions for foot and ankle deformities 14Moat top 45%Innovation top 49%Patents bottom 49%Talent bottom 49% All 7 signals ▾Moattop 45% Innovationtop 49% Patentsbottom 49% Talentbottom 49% Fundingbottom 45% Globalbottom 33% Marketbottom 17% Moat: Editorial + unicorn rating 4/10 · IP moat: 3 patents Innovation: 3 patents (top 91% of patent-holders) · 3 filings since 2022 vs 0 in 2017-21 rank vs industry peers · Fliar Intelligence Index 14/100 | $2M | 1 mo ago | 2 | William Rhoda Co-Founder | — | — | 3 patents Interphalangeal joint prosthetic devices and implantation techniques | — |
| 49 | Meduloc Developer of intramedullary implant for internal fixation of small bones fractures 45Moat top 38%Patents top 44%Talent top 45%Innovation bottom 49% All 6 signals ▾Moattop 38% Patentstop 44% Talenttop 45% Innovationbottom 49% Fundingbottom 48% Globalbottom 33% Moat: Editorial + unicorn rating 5/10 · IP moat: 19 patents Patents: 19 patents matched (strict assignee match) · 10 filings since 2022 vs 9 in 2017-21 rank vs industry peers · Fliar Intelligence Index 45/100 | $2M | 4 mo ago | — | Joshua Hustedt Co-Founder | — | — | 19 patents Orthopedic bone fixation implants such as plates, screws, and intramedullary nails. | 1 launch · 1 partnership |
| 50 | Lenoss Medical Developer of implants for the treatment of spinal fractures 11Funding top 47%Talent bottom 49%Global bottom 29%Market bottom 23% All 4 signals ▾Fundingtop 47% Talentbottom 49% Globalbottom 29% Marketbottom 23% Funding: Raised $1.3M across 2 rounds · 2 rounds over 5 yrs (0.4/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 11/100 | $1M | 3 mo ago | 9 | Dom Messerli CEO & President | — | — | — | 1 partnership |
Top 12 Orthopedics companies in United States
#1
Public · San Francisco, California · founded 2012 · 21 employees$420.1Mraised▾
Public · San Francisco, California · founded 2012 · 21 employees
Developer of therapeutics for orthopedic diseases. It offers a lead candidate NOV004 which is an anabolic peptide engineered to target and concentrate at the bone fracture site and also helps in spinal fusion and osteogenesis Imperfecta.
Fliar Intelligence Index™ 53how this company ranks against its industry peers
Funding
top 13%Growth
top 37%Tech
top 44%Moat
top 48%Talent
bottom 49%Market
bottom 37%Funding: Raised $420M across 7 rounds · 7 rounds over 12 yrs (0.6/yr) · Last round Post IPO (May 2026)
Growth: Web rank 50,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo
Tech: 37 technologies across 3/8 capability areas · Cloud: Amazon Web Services, Cloudflare · Security: Cloudflare Bot Management, Hsts
Audience (LinkedIn): 4k LinkedIn followers
Activity (LinkedIn): 1 product launches · 1 partnerships (incl. LifeSci Capital) announced in 12 mo
Funding rounds
- May 2026Post IPO$187M
- Feb 2020Post IPO$125M
- May 2018Series B$84.5M
- Feb 2017Series A$7.6M
Founders & team
Investors
Breakout Labs, Dolby Family Ventures, Takeda, Pfizer Venture Investments, Takeda Ventures, Sequoia Capital
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform LaunchAmazon Web Services
#2
Public · Cambridge, Massachusetts · founded 2019 · 133 employees$477.1Mraised▾
Public · Cambridge, Massachusetts · founded 2019 · 133 employees
Developer of therapeutics to treat acute myeloid leukemia. The company has developed cancer therapeutics using engineered hematopoietic stem cells (eHSC). The company's lead candidate includes VOR33 which targets CD33 protein in cancer patients to treat acute myeloid leukemia (AML).
Fliar Intelligence Index™ 78how this company ranks against its industry peers
Funding
top 12%Patents
top 19%Innovation
top 20%News
top 24%Talent
top 27%Moat
top 35%Funding: Raised $477M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) · Last round Post IPO (Dec 2025)
Patents: 188 patents matched (strict assignee match) · 154 filings since 2022 vs 34 in 2017-21 · Latest publication 2026
Innovation: 188 patents (top 13% of patent-holders) · 154 filings since 2022 vs 34 in 2017-21
Funding rounds
- Dec 2025Post IPO$150M
- Jun 2025Post IPO$175M
- Jul 2020Series B$110.1M
- Feb 2019Series A$42M
Founders & team
Investors
RA Capital Management, Forbion, Venrock, Caligan Partners, NEXTBio, Mingxin Capital
Tech stack
AddtoanyAddtoany Share ButtonsApple Icloud MailCloudflareCloudflare Bot ManagementCookiebot
#3
Public · Marlborough, Massachusetts · founded 2001$131.6Mraised▾
Public · Marlborough, Massachusetts · founded 2001
Developer of exoskeletons for individuals with spinal cord injuries and stroke rehabilitation. The company offerings include the rewalk personal exoskeleton, restore exo-suit, and myocycle FES systems for rehabilitation, recovery, and more to address physical disability.
Fliar Intelligence Index™ 50how this company ranks against its industry peers
Funding
top 22%Product
top 28%News
top 30%Partners
top 31%Tech
top 40%Growth
top 47%Funding: Raised $132M across 13 rounds · 13 rounds over 15 yrs (0.9/yr) · Last round Post IPO (Mar 2026)
Product: 1 published app (39 installs) · Company stage: Public
News: 10 BI events in 12 mo (of 23 tracked, 6 types) · -9% YoY · 5 high-value events (IPO/M&A/funding/contracts) in 12 mo
Audience (LinkedIn): 3k LinkedIn followers
Activity (LinkedIn): 1 product launches · 1 partnerships (incl. Oramed Pharmaceuticals Inc.) announced in 12 mo
Funding rounds
- Mar 2026Post IPO$20M
- Jan 2025Post IPO$5M
- Feb 2021Post IPO$40M
- Dec 2020Post IPO$8M
Founders & team
Investors
Proseed Venture Capital Fund, Kreos Capital, Yaskawa, Shavit Capital
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform LaunchAkamai
#4
Series B · Boston, Massachusetts · founded 2016 · 46 employees$72.5Mraised▾
Series B · Boston, Massachusetts · founded 2016 · 46 employees
Miach Orthopaedics is developing bio-engineered surgical implants for connective tissue repair. The company has developed a BEAR implant which is a proprietary bio-engineered sponge designed as a bridging scaffold to facilitate healing of the torn ACL (anterior cruciate ligament).
Fliar Intelligence Index™ 64how this company ranks against its industry peers
Funding
top 23%Talent
top 28%Patents
top 32%Moat
top 32%Growth
top 35%Innovation
top 39%Funding: Raised $72.5M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) · Last round Series B (May 2026)
Talent: Analyst team rating 5/5 · 2 named leaders on record · 2 C-suite/founder profiles curated
Patents: 33 patents matched (strict assignee match) · 33 filings since 2022 vs 0 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 9k LinkedIn followers — 4.7% of this cohort's audience
Funding rounds
- May 2026Series B$6.5M
- Oct 2025Conventional Debt$7.5M
- Apr 2024Series B$20M
- Jan 2023Series B$30M
Founders & team
Investors
SVB, Sectoral, Endeavour Vision, Amzak Health, Smith+Nephew, NFLPA
Tech stack
CloudflareCloudflare Bot ManagementCore-JsCrazy EggFacebook PixelFancybox
#5
Series D · Woodland Hills, California · founded 2018$156Mraised▾
Series D · Woodland Hills, California · founded 2018
Developer of drugs for muscle, bone, and joint diseases. The company's products include AGAO1 for bone fusion, AGA02 for rare diseases, AGA03 for regeneration, AGA04 for osteoporosis, AGA05 for healing, and others. Also, developed many drugs for multiple disease treatments such as nonunion of fractures, osteoarthritis, rare diseases of skeletal muscle, and mineral metabolism diseases caused by diseases or disorders of endocrine organs.
Fliar Intelligence Index™ 29how this company ranks against its industry peers
Funding
top 16%Talent
top 38%Moat
top 47%Market
bottom 40%Global
bottom 39%Innovation
bottom 23%Funding: Raised $156M across 5 rounds · 5 rounds over 6 yrs (0.8/yr) · Last round Series D (Feb 2026)
Talent: 2 named leaders on record · 2 C-suite/founder profiles curated
Moat: Editorial + unicorn rating 5/10 · IP moat: 4 patents · 10 curated direct competitors tracked
Audience (LinkedIn): 4k LinkedIn followers
Funding rounds
- Feb 2026Series D$130M
- Dec 2024Series C$120M
- Jan 2024Series B$40M
- Oct 2023Series B$46M
Founders & team
Investors
Hillhouse, TF Capital, Yonghua Capital, Global Sources, Guangzhou Hi-Tech Communication Technology, Guangdong Capital
#6
Series D · Marietta, Georgia · founded 2015 · 94 employees$65Mraised▾
Series D · Marietta, Georgia · founded 2015 · 94 employees
Developer of rhenium-based implants for spine surgeries. The company has developed a MoRe, a proprietary molybdenum-rhenium superalloy for medical implants. This system can be used in adult spine deformity constructs.
Fliar Intelligence Index™ 60how this company ranks against its industry peers
Patents
top 11%Innovation
top 12%Funding
top 21%Moat
top 26%Product
top 30%Market
bottom 44%Patents: 288 patents matched (strict assignee match) · 190 filings since 2022 vs 82 in 2017-21 · Latest publication 2026
Innovation: 288 patents (top 8% of patent-holders) · 190 filings since 2022 vs 82 in 2017-21 · Deep-tech classification: Tech Hardware
Funding: Raised $65.0M across 2 rounds · 2 rounds over 5 yrs (0.4/yr) · Last round Series D (May 2026)
Audience (LinkedIn): 10k LinkedIn followers — 5.0% of this cohort's audience
Funding rounds
- May 2026Series D$1.5B
- Jul 2021Series C$65M
Investors
Mammoth, Boston Scientific
Tech stack
Amazon Web ServicesApache Http ServerAstraBeaver BuilderCloudflareCloudflare Bot Management
#7
Public · Cambridge, Massachusetts · founded 2014 · 101 employees$92.5Mraised▾
Public · Cambridge, Massachusetts · founded 2014 · 101 employees
Developer of gene therapy platform for Duchenne muscular dystrophy. The lead candidate SGT-001 is Microdystrophin, a synthetic version of the dystrophin gene which stabilizes the muscle membrane and dystrophin-glycoprotein complex. Also, developed a soft wearable device for mobility and help preserve muscle function.
Fliar Intelligence Index™ 53how this company ranks against its industry peers
Patents
top 20%Funding
top 24%Innovation
top 31%Tech
top 33%Moat
top 38%News
top 48%Patents: 60 patents matched (strict assignee match) · 43 filings since 2022 vs 17 in 2017-21 · Latest publication 2026
Funding: Raised $92.5M across 7 rounds · 7 rounds over 11 yrs (0.6/yr) · Last round Post IPO (Mar 2026)
Innovation: 60 patents (top 27% of patent-holders) · 43 filings since 2022 vs 17 in 2017-21
Funding rounds
- Mar 2026Post IPO$240M
- Jan 2024Post IPO$108.9M
- Dec 2020Post IPO$90M
- Oct 2020Post IPO$40M
Investors
RA Capital Management, RTW Investments, Foresite Capital, Perceptive Advisors, Janus Henderson Investors, Biogen
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform LaunchAmazon Web Services
#8
Public · San Jose, California · founded 2012 · 163 employees$234.1Mraised▾
Public · San Jose, California · founded 2012 · 163 employees
Developer of technology for the oral delivery of large drug molecules. The company has a proprietary platform is capable of delivering a wide range of biologics for the treatment of various chronic diseases. The company develops RaniPill capsule has broad applications for the treatment of acromegaly, rheumatoid arthritis, psoriatic arthritis, growth hormone deficiency, osteoporosis, Crohn’s disease, hemophilia, diabetes, among other diseases.
Fliar Intelligence Index™ 72how this company ranks against its industry peers
Growth
top 22%Funding
top 23%Patents
top 24%Talent
top 27%Innovation
top 28%News
top 30%Growth: Revenue +59% YoY · Fresh capital in last 24 mo
Funding: Raised $234M across 6 rounds · 6 rounds over 13 yrs (0.5/yr) · Last round Post IPO (Oct 2025)
Patents: 456 patents matched (strict assignee match) · 180 filings since 2022 vs 204 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 6k LinkedIn followers — 3.0% of this cohort's audience
Activity (LinkedIn): 1 product launches announced in 12 mo
Funding rounds
- Oct 2025Post IPO$60.3M
- Dec 2020Series E$69M
- Nov 2020Series E$50M
- Feb 2018Series E$53M
Founders & team
Investors
GeneScience Pharmaceuticals, Shire, Cathay Financial Holdings, Google Ventures, Novartis, AstraZeneca
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform LaunchAkamai
#9
Series C · Burlington, Massachusetts · founded 2023$51.7Mraised▾
Series C · Burlington, Massachusetts · founded 2023
Developer of biologic therapeutic engineered for orthopedic conditions treatment. The company focuses on developing a multi-protein therapeutic to target disease drivers. Its management team has experience in biologic drug development. The company's asset is for chronic lumbosacral radiculopathy.
Fliar Intelligence Index™ 35how this company ranks against its industry peers
Funding
top 28%Talent
bottom 49%Global
bottom 25%Funding: Raised $51.7M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) · Last round Series C (Mar 2026)
Talent: 1 named leader on record · 1 C-suite/founder profile curated
Global: Single-market focus (United States)
Audience (LinkedIn): 344 LinkedIn followers
Funding rounds
- Mar 2026Series C$34.8M
- Oct 2024Series B$16.8M
Founders & team
#10
Series D · San Clemente, California · founded 2013 · 13 employees$110.8Mraised▾
Series D · San Clemente, California · founded 2013 · 13 employees
Developer of pharmaceuticals for musculoskeletal therapeutics to treat orthopedic infections. The company lead product VT-X7 is for Periprosthetic joint infection and targets chronic bacterial PJI. Another drug candidate A-103 is for fungal PJI. The company offers its drug-device combination product for antibiotic therapy for local delivery to treat infected joint prostheses like bacterial and fungal infections for joints like shoulder, knee, and hip.
Fliar Intelligence Index™ 29how this company ranks against its industry peers
Funding
top 19%Moat
top 38%Talent
bottom 49%Global
bottom 37%Market
bottom 31%Funding: Raised $111M across 7 rounds · 7 rounds over 8 yrs (0.9/yr) · Last round Series D (Oct 2025)
Moat: Editorial + unicorn rating 5/10 · Soonicorn
Talent: 1 named leader on record · 1 C-suite/founder profile curated
Audience (LinkedIn): 4k LinkedIn followers
Hiring (LinkedIn): 9 hiring posts in 12 mo (public) · momentum +9 · hiring: Area Vice President (East/West), Account Manager
Funding rounds
- Oct 2025Series D$15.6M
- May 2024Series D$50M
- Sep 2023Series C$23M
- Mar 2022Series B$30M
Founders & team
Investors
Gideon Strategic Partners, Johnson & Johnson Innovation – JJDC, Prism Ventures, Medvest Capital, HM Venture Partners, Huimei Capital
#11
Series A · San Francisco, California · founded 2018$18.7Mraised▾
Series A · San Francisco, California · founded 2018
Provider of a wearable medical device that utilizes targeted mechanical stimulation to deliver patented therapy for low bone density. The device offers a non-pharmacological treatment option for postmenopausal women with osteopenia that provides precise vibrations to the lumbar spine and hips to reduce bone strength and density decline.
Fliar Intelligence Index™ 67how this company ranks against its industry peers
Tech
top 17%Talent
top 28%Funding
top 34%Growth
top 35%Global
bottom 48%Market
bottom 40%Tech: 49 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 · Devops: Nginx
Talent: 4 named leaders on record · 4 C-suite/founder profiles curated
Funding: Raised $18.7M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) · Last round Series A (Apr 2026)
Funding rounds
- Apr 2026Series A$8M
- Mar 2023Series A$5M
- May 2021Seed$2.5M
- Aug 2019Seed$505K
Founders & team
Investors
Good Growth Capital, Ambit Health Ventures, Portfolia, Golden Seeds, Berkeley Angel Network, Reno Seed Fund
Tech stack
Amazon CloudfrontAmazon S3Amazon Web ServicesAmplitudeApolloApplovin
#12
Series A · Atlanta, Georgia · founded 2001 · 77 employees$45Mraised▾
Series A · Atlanta, Georgia · founded 2001 · 77 employees
OXOS Medical is a developer of orthopedic imaging devices and software. The company has developed a handheld fluoroscopy device called Micro C that enables surgeons and physicians to capture images of the extremities for orthopedic procedures.
Fliar Intelligence Index™ 57how this company ranks against its industry peers
Funding
top 24%Growth
top 28%Tech
top 43%Product
top 47%Moat
top 48%Talent
bottom 49%Funding: Raised $45.0M across 9 rounds · 9 rounds over 5 yrs (1.8/yr) · Last round Series A (Dec 2025)
Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo
Tech: 36 technologies across 4/8 capability areas · Cloud: Cloudflare · Devops: Nginx
Audience (LinkedIn): 6k LinkedIn followers — 2.9% of this cohort's audience
Activity (LinkedIn): 1 product launches · 1 partnerships (incl. GlobalMed) announced in 12 mo
Funding rounds
- Dec 2025Series A$10.7M
- Apr 2023Series A$23M
- Feb 2022Series A$8.2M
- Feb 2021Series A$4.4M
Founders & team
Investors
Parkway VC, Intel Capital, FedTech, MedTech Innovator, Chang Robotics Fund
Tech stack
AdrollAdroll Cmp SystemApple Icloud MailCallrailCdnjsCloudflare
Funding & investor landscape
$15.6Btotal disclosed funding
522companies funded
1,921disclosed rounds
7rounds last 90 days
Most active investors
New Enterprise Associates16 rounds
Notable founders
Dirk Thye
CEO · Quince Therapeutics
Siddhartha Mukherjee
Founder · Vor Biopharma
Robert Ang
President and CEO · Vor Biopharma
Larry Jasinski
CEO & MD · Lifeward
Martha Murray
Founder · Miach Orthopaedics
Patrick McBrayer
President & CEO · Miach Orthopaedics
Muyu Li
Co-Founder & COO · Angitia
Hua Ke
Co-Founder & CEO · Angitia
Mir Imran
Founder · Rani Therapeutics
Talat Imran
CEO · Rani Therapeutics
Andrew Hall
CEO · Consano Bio
David Thompson
Chairman and Chief Executive Officer · Osteal Therapeutics
Prism market signals · United States · country-scoped Prism corpus, 517,506 docs
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth flat
RESEARCH SIGNALS · United States
How research on Medical Devices is moving in the United States
A read on the academic research around Medical Devices — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,830 United States-affiliated papers.
research sentiment over time
200820172026
enthusiastic · positive · guarded tone
Tone is overwhelmingly optimistic and intensifying — the enthusiastic (strongly-positive) share moved 43% → 57% across 2008–2026.
top research entities
- Johns Hopkins University74
- United States Food and Drug Administration59
- Harvard University54
- Center for Devices and Radiological Health53
- Design Intelligence36
leading researchers
www.rasitdinc.com · , Elena · Dmitry Oleynikov · Joseph S. Ross · Shane Farritor · Carl A. Nelson · Raşit Dinç · Barbara Christe
▲
Breakthroughs295 · 16%
▲ 15%→16% share
▲1.1× share momentum1 median citations53% since 2021mostly methods-led
Robotics research is surging — U.S. biocompatible-material papers nearly quintupled (2→9) and robotics doubled (7→13) in Breakthroughs.
rising sub-themes (early→recent)
- Biocompatible material2→9
- Robotics7→13
- Health care1→6
- Tissue engineering1→5
- Automation1→5
Newly emergingWearable computer 0→7 · Gelatin 0→6 · Antimicrobial 0→6
Landmark Nanostructured Titanium for Biomedical Applications · 258 cites
◆
Advancements555 · 30%
31%→31% share
▲1.0× share momentum1 median citations53% since 2021mostly methods-led
Robotic surgery advancement is intensifying — U.S. papers rose from 18 to 29, with Health care topics exploding from 2 to 24.
rising sub-themes (early→recent)
- Health care2→24
- MEDLINE1→21
- Quality (philosophy)3→15
- Robotic surgery18→29
- Product (mathematics)5→16
Newly emergingClearance 0→6 · Wearable computer 0→6 · Single use 0→6
Landmark New Technology and Health Care Costs — The Case of Robot-Assisted Surgery · 962 cites
▼
Concerns582 · 32%
▼ 35%→31% share
▼0.9× share momentum1 median citations51% since 2021mostly position pieces
Patient-safety concern is rising — MEDLINE-indexed safety papers surged from 1 to 36, with confidentiality newly emerging at 8 papers.
rising sub-themes (early→recent)
- MEDLINE1→36
- Robotic surgery7→24
- Patient safety19→32
- Key (lock)6→19
- Quality (philosophy)10→20
Newly emergingSystematic review 0→9 · Confidentiality 0→8 · Workflow 0→6
Landmark Current and emerging applications of 3D printing in medicine · 581 cites
RESEARCH HOTSPOTS · United States
Where medical devices is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Boston116 · +0.15
SF Bay Area70 · +0.06
New York59 · +0.21
Seattle40 · +0.25
Los Angeles36 · +0.38
Chicago33 · +0.16
Philadelphia28 · +0.12
San Diego27 · +0.36
Pittsburgh25 · +0.44
Atlanta23 · +0.43
PATENT SIGNAL · United States
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
666,693 filings8,000 assigneespeak 71776/yr2016–2025
filing momentum (YoY 2016–2025)
top patent filers
- Covidien29351
- Boston Scient Scimed24775
- Medtronic22434
- Becton Dickinson18269
- Procter & Gamble16210
- Ethicon ENDO Surgery13758
- Kimberly Clark12462
- Ethicon11769
Common questions
How many Orthopedics companies are there in United States?
Radar tracks 1157 indexable Orthopedics companies headquartered in United States that meet our profile-completeness bar.
What is the total funding raised by Orthopedics companies in United States?
The Orthopedics companies in United States on this list have raised a combined $15.6B in disclosed equity funding across 522 funded companies.
Which is the highest-funded Orthopedics company in United States?
Biosplice is the highest-funded Orthopedics company in United States, with $778M in disclosed equity funding.
How many Orthopedics companies in United States are funded?
522 of the 1157 Orthopedics companies in United States on this list have disclosed at least one equity funding round.
How many Orthopedics unicorns are there in United States?
1 Orthopedics company in United States on this list is valued at $1B or more.
Who are the top investors in United States Orthopedics companies?
The most active investors in United States Orthopedics companies on this list include HHS, National Science Foundation, New Enterprise Associates, MassChallenge, MB Venture Partners.
Riya SenguptaFinancials
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.