Best Orthopedics Companies in France
The 117 best Orthopedics companies in France in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Medicrea.
France's Orthopedics sector has 117 companies on our radar, with $445M in total disclosed funding and not a single unicorn in sight. So where's the action? Wandercraft leads the funding table at $67M, followed by Kinvent at $27M and 4Moving Biotech at $22M, and the investor roster, Bpifrance, GO Capital, Turenne Groupe, Europa, Idinvest Partners, reads like a who's who of French deep-tech backers. Globally, the orthopedics market sits at roughly $23.4B, pulled forward by aging populations and rising surgical volumes, and Zimmer Biomet's strong 2026 start signals that even the big globals are leaning in.
Revenue tells a more complicated story. Across six filers I track here, combined revenue pools at $53M, but the median company clears just $4M with flat-to-negative growth year on year. Amplitude is the clear outlier at $29M, seven times the sector median, and Spineway holds its own at $13M and growing. Coverage themes are shifting hard toward specialty orthopedic facilities and surgical centers, which means if you're mapping the French market, the opportunity isn't just in devices. It's in care infrastructure around them.
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in France
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Medicrea Surgical devices for spinal and orthopedic surgeries | $83M | 90 mo ago | 175 | Denys Sournac Founder | Javaparticles.jsASP.NET Boilerplate+10 | Top 50M | 289 patents Spinal fixation and intervertebral disc replacement devices for vertebrae surgery | — |
| 2 | Wandercraft Provider of AI-powered exoskeleton solutions 74Innovation top 19%Patents top 22%Moat top 26%Talent top 28% All 13 signals ▾Innovationtop 19% Patentstop 22% Moattop 26% Talenttop 28% Fundingtop 31% Growthtop 35% Producttop 36% AItop 45% Markettop 46% Fin. healthbottom 46% Techbottom 45% Globalbottom 42% Newsbottom 18% Innovation: 132 patents (top 15% of patent-holders) · 78 filings since 2022 vs 41 in 2017-21 Patents: 132 patents matched (strict assignee match) · 78 filings since 2022 vs 41 in 2017-21 rank vs industry peers · Fliar Intelligence Index 74/100 | $67M | 12 mo ago | 117 | Alexandre Boulanger Co-Founder | Webflow EcommerceWebflowAxeptio+15 | Top 10M | 132 patents Powered lower-body exoskeletons with 3‑DOF hip joints and AI‑based gait stabilization | 2 partnerships |
| 3 | EOS Iamging Developer of 2d/3D orthopedic imaging and software solutions | $44M | 95 mo ago | 175 | — | WordPressMySQLPHP+19 | Top 10M | — | — |
| 4 | SpineVision Developer of implants for spinal treatment | $36M | 157 mo ago | 50 | Arnaud Brisard Chief Executive Officer | WordPressMySQLPHP+26 | Top 50M | 142 patents Spinal implant devices and dynamic fixation systems for vertebral surgery | — |
| 5 | Kinvent Provider of a device for physical rehabilitation and sports biomechanics 42Product top 34%Funding top 35%Talent top 38%Growth top 45% All 8 signals ▾Producttop 34% Fundingtop 35% Talenttop 38% Growthtop 45% Techtop 45% Globalbottom 36% Marketbottom 34% Newsbottom 22% Product: 4 published apps (8.1k installs) · Company stage: Series B Funding: Raised $27.4M across 3 rounds · 3 rounds over 8 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $27M | 29 mo ago | — | Odys Odys Co-CEO | WordPressMySQLPHP+24 | Top 5M | — | — |
| 6 | InnoSkel Developer of novel therapeutic solutions for the treatment of skeletal disorders | $24M | 66 mo ago | 27 | Elvire Gouze Founder & CEO | — | — | 6 patents Gene‑based therapies targeting collagen synthesis and bone fragility disorders | — |
| 7 | 4Moving Biotech Developer of therapeutics designed to translate scientific research into medicine 42Growth top 28%Moat top 32%Funding top 39%Patents top 40% All 9 signals ▾Growthtop 28% Moattop 32% Fundingtop 39% Patentstop 40% Innovationtop 44% Talentbottom 49% Techbottom 35% Globalbottom 35% Marketbottom 29% Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo Moat: Editorial + unicorn rating 4/10 · IP moat: 25 patents rank vs industry peers · Fliar Intelligence Index 42/100 | $22M | 4 mo ago | — | Francis Berenbaum Co-Founder | WordPress Block EditorWordPressMySQL+12 | Top 10M | 25 patents Cartilage regeneration therapeutics targeting chondrocyte proliferation and joint disease treatment | — |
| 8 | Hyprevention Developer of implantable orthopedic medical devices | $21M | 26 mo ago | 8 | — | — | — | 38 patents Orthopedic bone fixation implants for fractured and non‑fractured bones | — |
| 9 | Safe Orthopedics Single use instruments for lumbar Spine surgery | $14M | 66 mo ago | 136 | — | Apple iCloud MailMicrosoft 365Vue.js+5 | Top 50M | — | — |
| 10 | Evolutis Manufacturer of orthopaedic prosthesis and implants | $13M | 113 mo ago | 160 | — | — | — | 36 patents Orthopedic joint implants and interchangeable surgical instrument handles for knee prostheses. | 1 internship |
| 11 | Graftys Developer of bone graft substitutes and biocompatible filling materials | $12M | 47 mo ago | 25 | — | — | — | 75 patents Injectable calcium‑phosphate bone and dental cements with blood or hyaluronic acid additives | — |
| 12 | Implanet Developer of implants for orthopedic surgery | $10M | 103 mo ago | 42 | — | WordPressMySQLPHP+16 | Top 10M | 121 patents Spinal vertebra fixation systems and bone band attachment devices for orthopedic surgery. | — |
| 13 | In'Tech Medical Surgical instruments for orthopaedic industry | $9M | 49 mo ago | 271 271 → 499 (+84%) | Malpiece Co-Founder | Cart FunctionalityJoomlaPHP+20 | Top 10M | — | — |
| 14 | Dedienne Sante A range of orthopedic implants | $9M | 216 mo ago | 450 | — | WordPressMySQLPHP+21 | Top 10M | 55 patents Orthopedic implant anchoring devices and surgical tools for hip replacement procedures. | 1 expansion |
| 15 | Regulaxis French Biopharma R&D company working on synthetic drugs as well as regenerative medicine | $7M | 72 mo ago | 6 | Claude Carelli Founder & CEO | — | — | 10 patents Therapeutic peptides targeting osteoarthritis inflammation and cartilage regeneration | — |
| 16 | Peptinov Developer of anti-cytokine immunotherapies for the treatment of chronic inflammatory diseases | $6M | 30 mo ago | 8 | Rene Azoulai CEO | — | — | 33 patents Therapeutic peptide vaccines and antibody platforms targeting inflammatory cytokines and lymphocyte selection. | — |
| 17 | In2Bones Provider of single use surgical instruments and orthopedic implants for use in lower extremity surgeries. | $6M | 103 mo ago | 62 | — | — | — | 93 patents Orthopedic tibial and ankle joint replacement implants and surgical instrumentation | 1 launch |
| 18 | Biomatlante Biphasic synthetic bone grafts for bone regeneration using MBCP Technology. | $5M | 113 mo ago | 32 | — | JoomlaApple iCloud MailMicrosoft 365+14 | Top 10M | 38 patents Bone regeneration scaffolds: hydrogels, dehydrated granules, contrast‑enhanced bone substitutes. | — |
| 19 | Memometal Hand, Wrist, Foot, Ankle implants made using proprietary alloys | $4M | 195 mo ago | 49 | Dougal Bendjaballah CEO & President | — | — | 123 patents Orthopedic bone fixation and arthroplasty implants for hand, foot, and ankle surgery | — |
| 20 | RB3D Robotics Developer of cobots and exoskeletons | $3M | 156 mo ago | 9 | Serge Grygorowicz CEO & Technical Director | — | — | — | — |
| 21 | REEV Developer of AI-powered exoskeletons and gait analysis tools for mobility recovery. 48Growth top 35%Talent top 38%Funding top 40%AI top 45% All 8 signals ▾Growthtop 35% Talenttop 38% Fundingtop 40% AItop 45% Producttop 46% Techbottom 47% Globalbottom 43% Marketbottom 26% Growth: Fresh capital in last 24 mo Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 48/100 | $3M | 16 mo ago | 16 | Robin Temporelli CTO & Co-Founder - Technical and operational manager for the development of electromedical products | WordPressMySQLPHP+29 | Top 10M | — | — |
| 22 | ASTON Medical Hip, knee and shoulder implants | $3M | 203 mo ago | 33 | — | — | — | 44 patents Surgical instrumentation and alignment devices for knee and shoulder joint prosthesis implantation | — |
| 23 | ORTHOPUS Provider of hardware to help the motor handicap | $3M | 40 mo ago | 17 | — | WordPressMySQLPHP+20 | Top 5M | 2 patents Articulated wheelchair arm mechanisms for enhanced patient positioning and support | — |
| 24 | Biophytis Developer of drugs for neuromuscular and age-related diseases 45Patents top 32%Moat top 35%Funding top 37%Innovation top 38% All 10 signals ▾Patentstop 32% Moattop 35% Fundingtop 37% Innovationtop 38% Globaltop 45% Partnerstop 45% Newstop 46% Growthbottom 47% Techbottom 43% Marketbottom 42% Patents: 175 patents matched (strict assignee match) · 62 filings since 2022 vs 105 in 2017-21 Moat: Editorial + unicorn rating 5/10 · IP moat: 175 patents rank vs industry peers · Fliar Intelligence Index 45/100 | $3M | 3 mo ago | 24 | — | WordPressPleskMySQL+21 | Top 10M | 175 patents Phytoecdysteroid-based therapeutics for muscle, metabolic, respiratory, and ocular disorders | 1 expansion |
| 25 | Japet Medical Devices Exoskeleton for the relief from lower back pain | $2M | 103 mo ago | 40 | Damien Bratic Co-Founder & CTO | WordPressMySQLPHP+25 | Top 5M | — | — |
| 26 | BONE 3D Developer of smart plastic surgery devices | $2M | 78 mo ago | 26 | Jeremy Adam Founder & President | — | — | 30 patents 3D‑printed nasal prostheses and realistic surgical training simulators for ENT procedures | — |
| 27 | Vytruve 3D printing and scanning systems for orthopedics | $2M | 27 mo ago | — | Erwan Calvier Founder & CEO | Cart FunctionalitySquarespace CommerceSquarespace+25 | Top 50M | 16 patents Digital acquisition and modeling of prosthetic limb sockets for custom fit manufacturing. | — |
| 28 | Aqualeg Developer of a solution for protecting the prostheses | $1M | 159 mo ago | 5 | Frederic Rauch CEO | Node.jsRadix UITailwind CSS+13 | Top 50M | 9 patents Advanced protective and aesthetic coverings for prosthetic limbs and their manufacturing processes. | — |
| 29 | Dessintey Developer of intensive rehabilitation technologies designed to accelerate patient return to autonomy | $1M | 84 mo ago | 18 | Pascal Giraux Co-Founder | WordPressMySQLPHP+22 | Top 5M | 23 patents Neurorehabilitation devices for upper and lower limb motor and cognitive therapy | — |
| 30 | Recfrance Developer of a wide range of orthopedic paramedical equipment | $1M | 149 mo ago | 18 | Richard Juszkiewicz Co-Founder & President | — | — | 12 patents Orthopedic patient positioning and mobility assistance devices, including connected lifting systems. | — |
| 31 | Neosteo Knee osteotomy implant solutions | $1M | 168 mo ago | 13 | Guillaume Derouet Co-Founder | — | — | 60 patents Foot and ankle arthroereisis implants and polyaxial bone fixation devices | — |
| 32 | GeNouRoB Medical devices to measure knee ligament laxity and enhance rehabilitation | $418K | 78 mo ago | 21 | stephane new CEO | VideoJSJW PlayerFlowplayer+6 | Top 50M | 18 patents Non‑invasive detection and therapeutic monitoring of knee ligament (especially ACL) injuries | — |
| 33 | ASTON-SEM Manufacturer of orthopedic prostheses and implants | $262K | 114 mo ago | 54 | Soman George Owner | — | — | — | — |
Top 12 Orthopedics companies in France
#1
Series B · Lille, Hauts-de-France · founded 2020$22.1Mraised▾
Developer of therapeutics designed to translate scientific research into medicine. The focus is on bridging the gap between scientific discoveries and patient care. It concentrates on creating and advancing therapeutic solutions. The organization aims to address unmet medical needs through its pipeline.
- Feb 2026Series B$14.2M
- 2025Grant (prize money)$7.9M
#2
Series D · Paris, Ile de France · founded 2012 · 117 employees$67.1Mraised▾
Provider of AI-powered exoskeleton solutions. It is a personal-use exoskeleton designed for everyday indoor and outdoor walking without crutches, currently undergoing clinical trials.
- Jun 2025Series D$75M
- Apr 2024Venture Debt$27.1M
- Jan 2022Series C$45M
- Jan 2018Grant (prize money)$675.6K
#3
Public · Romainville, Ile de France · founded 2006 · 24 employees$2.6Mraised▾
Developer of drugs for neuromuscular and age-related diseases. The company's lead drug candidate, Sarconeos (BIO101), is an orally administered small molecule in development for the treatment of neuromuscular diseases, including sarcopenia and DMD. Other drug candidate, Macuneos (BIO201) for the treatment of retinal diseases, including dry AMD and Stargardt disease.
- Mar 2026Post IPO$1.6M
- Jun 2021Post IPO$38.2M
- Jul 2020Post IPO$6.9M
- Oct 2017Post IPO$12.3M
#4
Series B · Toulouse, Occitanie · founded 2021 · 16 employees$3.2Mraised▾
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- Feb 2025Series B$9.2M
- Sep 2023Series A$3.2M
- Jan 2023Seed$20K
#5
Series B · Pessac, Nouvelle Aquitaine · founded 2010 · 8 employees$21.4Mraised▾
Developer of implantable orthopedic medical devices. The products of the company include Y-STRUT an implantable medical device for internal fixation of proximal femur of patients at risk of osteoporotic fracture and for impeding pathological fracture and V-STRUT is a Percutaneous Vertebral Augmentation device for the treatment of the vertebral fracture.
- Apr 2024Series B$16.1M
- Mar 2022Series A$4.5M
- Sep 2020Series A—
- Dec 2015Seed$824K
#6
Series B · Montpellier, Occitanie · founded 2016$27.4Mraised▾
Provider of a device for physical rehabilitation and sports biomechanics. It produces measuring and training devices for physiotherapy and fitness, including the K-Move joint mobility assessment tool and K-Force Plates for measuring balance. It also offer the Kinvent Physio app for physiotherapists and athletic trainers.
- Jan 2024Series B$19.6M
- 2022Series A$7.5M
- Nov 2018Seed$337.7K
#7
Acquired · La Rochelle, Nouvelle Aquitaine · founded 1990 · 175 employees$83.1Mraised▾
Medicrea develops products for spinal and orthopedic surgery. The company operates internationally covering USA, France etc. The company's products include PASS range (PASS LP and LigaPass 2.0); Cervical range (C-Jaws, Impix-C, Impix-Manta) which are used in the treatment of spinal pathologies such as scoliosis, spondylolythesis, and spinal fixations. The company offers TH-LUMBAR range of products in France and other countries except USA. The company also manufactures 3D printed spine implants. The products are FDA cleared and CE marked.
- Nov 2018Conventional Debt$30M
- Jul 2018Post IPO$3.6M
- Dec 2017Post IPO$8.5M
- Jun 2017Post IPO$14.6M
#8
Series A · Paris, Ile de France · founded 2010 · 8 employees$6Mraised▾
Peptinov is specialized in the development of anti-cytokine immunotherapies (vaccines) for the treatment of chronic inflammatory diseases and cancer. It has developed three innovative vaccines against IL6, IL1, and IL23 cytokines, which have successfully been tested in mice and/or in monkeys. Its drug pipeline includes PPV-06 (anti-IL6 vaccine); PPV-01 (anti-IL1b vaccine); PPV-03 (anti-IL23 vaccine). It is developing these vaccines to treat chronic inflammatory diseases such as rheumatoid arthritis and systemic sclerosis. Also developing small molecule inhibitors of cytokines using the proprietary in silico drug design approach.
- Nov 2023Grant (prize money)$2.7M
- Nov 2023Series A$6M
#9
Acquired · Paris, Ile de France · founded 1989 · 175 employees$43.8Mraised▾
Developer of 2d/3D orthopedic imaging and software solutions. The EOS 2D/3D imaging system is a personalized imaging tool that gives a precise 3D image of the patient's skeleton in the upright position, with a very low radiation dose that can be used to inform all aspects of care.
- Jul 2018Post IPO$17.1M
- Jan 2015Conventional Debt$17.7M
- Apr 2010PE$16.7M
- Nov 2007PE$18.2M
#10
Series C · Aix en provence, Provence Alpes Cote d Azur · founded 2005 · 25 employees$12Mraised▾
Graftys develops bone graft substitutes, osteogenic materials, bone cement, and ceramics for bone void filling. The products include QuickSet, which is an injectable, self-hardening, macroporous, calcium-phosphate bone void filler cement covered by patent applications. It is used for bone reconstructive and trauma surgery, fracture repair, extremities or pelvis, complex fractures, joint arthroplasty, tibial osteotomy. It has received FDA clearance for three 510(k) applications with its calcium phosphate materials, which are also CE marked.
- Jul 2022Series C$2M
- Mar 2019Series C$4.7M
- Jan 2011Series C$5.3M
#11
Deadpooled · Valbonne, Provence Alpes Cote d Azur · founded 2020 · 27 employees$24.2Mraised▾
The developer of novel therapeutic solutions for the treatment of skeletal disorders. The company has developed a gene therapy for treating SEDc, severe skeletal, joint malformations, and abnormalities affecting the eyes and ears.
- Dec 2020Series A$24.2M
#12
Series B · Paris, Ile de France · founded 1999 · 50 employees$36.1Mraised▾
SpineVision is involved in the development and marketing of implants and instrumentation for spinal treatment. Its products offer solutions for spinal pathologies including lumbar degenerative disc diseases, deformities, cervical disorders, trauma, and tumors. Its new generation products Flex+2 and LUMIS offer a stabilization system which can be used in a percutaneous approach.
- May 2013Series B$10M
- Jul 2011Series B$5M
- Dec 2005Series B$16M
- Jul 2001Series A$5.1M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.