Best Chemicals and Materials Companies in Massachusetts, United States
The 164 best Chemicals and Materials companies in Massachusetts, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Entegris.
Our analysis of 50 Chemicals and Materials companies
$3.9b in tracked funding; 74% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Chemicals and Materials companies in Massachusetts
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Entegris Provider of materials handling solutions for manufacturing processes 80Innovation top 9%Patents top 10%Funding top 19%Market top 28% All 12 signals ▾Innovationtop 9% Patentstop 10% Fundingtop 19% Markettop 28% Moattop 29% Fin. healthtop 34% Producttop 35% Techtop 36% Talentbottom 49% Newsbottom 46% Globalbottom 44% Growthbottom 42% Innovation: 6,814 patents (top 3% of patent-holders) · 2910 filings since 2022 vs 1663 in 2017-21 Patents: 6,814 patents matched (strict assignee match) · 2910 filings since 2022 vs 1663 in 2017-21 rank vs industry peers · Fliar Intelligence Index 80/100 | $1.3B | 23 mo ago | 1,361 | 1966 | Bertrand Loy CEO | Apple iCloud MailMicrosoft 365ZURB Foundation+30 | 6,814 patents Semiconductor wafer cleaning, polishing, filtration, and materials handling technologies. | — |
| 2 | Evolved By Nature Developer of bioactive peptides derived from silk protein for skincare | $190M | 47 mo ago | 101 | 2013 | Gregory Altman Co-Founder & CEO | — | 230 patents Silk-based biopolymers for performance textiles, cosmetics, and hyaluronic‑acid medical fillers | 1 award |
| 3 | FRX Polymers Manufacturer of environmentally flame retardant solutions for consumer and industrial use | $102M | 80 mo ago | 13 | 2007 | Marc Lebel CEO | — | 257 patents Flame‑retardant polyphosphonate additives enhancing impact resistance in polymer blends. | — |
| 4 | SemEquip Offers research, development, and manufacturing of implant materials for memory chips and semiconductors | $34M | 250 mo ago | 1,075 | 2000 | — | — | 244 patents Boron cluster synthesis and ion implantation for semiconductor defect engineering | — |
| 5 | Tiaxllc Developer of functional wearables and functional coatings for various applications | $32M | 64 mo ago | 75 | 2002 | — | — | — | — |
| 6 | Impact Nano Provider of product development, supplier management, metrology, and engineering services | $32M | 37 mo ago | 10 | 2019 | Matthew Stephens CEO | — | — | — |
| 7 | Clear Scientific Provider of platform to identify, neutralize, and eliminate harmful chemical compounds 19Funding top 31%Talent bottom 45%Global bottom 29%Market bottom 22% All 4 signals ▾Fundingtop 31% Talentbottom 45% Globalbottom 29% Marketbottom 22% Funding: Raised $23.9M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) Talent: 1 named leader on record rank vs industry peers · Fliar Intelligence Index 19/100 | $24M | 13 mo ago | 16 16 → 16 (+0%) | 2019 | Shekar Shetty CEO | — | — | — |
| 8 | Eiclabs Research and development corporation specializing in advanced materials and biomedical technology | $23M | 59 mo ago | — | 1996 | — | — | — | — |
| 9 | Addisenergy Developer of a subsurface process for producing ammonia from iron resources 27Talent top 23%Funding top 30%Global bottom 33%Market bottom 30% All 5 signals ▾Talenttop 23% Fundingtop 30% Globalbottom 33% Marketbottom 30% Techbottom 25% Talent: 8 named leaders on record · 7 C-suite/founder profiles curated Funding: Raised $17.2M across 3 rounds · 3 rounds over 1 yrs (3.0/yr) rank vs industry peers · Fliar Intelligence Index 27/100 | $17M | 7 mo ago | — | 2024 | Iwnetim Abate Co-Founder & Chief Scientific Officer | WordPressMySQLPHP+14 | — | — |
| 10 | CPS Leader in developing advanced materials solutions for transportation, energy, aviation, defense, and oil &… 53Funding top 32%Growth top 39%Fin. health top 42%Tech top 43% All 11 signals ▾Fundingtop 32% Growthtop 39% Fin. healthtop 42% Techtop 43% Newstop 45% Moatbottom 49% Marketbottom 44% Patentsbottom 44% Innovationbottom 37% Partnersbottom 35% Globalbottom 33% Funding: Raised $14.7M across 4 rounds · 4 rounds over 18 yrs (0.2/yr) Growth: Revenue +54% YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $15M | 8 mo ago | 86 | 1984 | — | WordPress Block EditorwpBakeryWordPress+29 | 10 patents Patents concentrated in mechanical & energy engineering | — |
| 11 | Agion Limited information available | $11M | 176 mo ago | 21 | 1997 | Stuart Patterson CEO | — | 39 patents Antimicrobial agrochemical formulations and controlled‑release food preservation additives. | — |
| 12 | LASE Innovation Developer of laser particle technology 13Funding top 40%Talent bottom 49%Global bottom 29%Market bottom 18% All 4 signals ▾Fundingtop 40% Talentbottom 49% Globalbottom 29% Marketbottom 18% Funding: Raised $6.6M across 6 rounds · 6 rounds over 6 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 13/100 | $7M | 15 mo ago | 10 | 2018 | Sheldon Kwok Co-Founder & CEO | — | — | — |
| 13 | Wild Microbes Manufacturer of sustainable products from plastics to protein materials | $3M | 39 mo ago | 10 | 2022 | — | Cart FunctionalitySquarespace CommerceSquarespace+9 | — | — |
| 14 | Nanoscale Powders Manufacturer of popcorn, namkeen, and snack foods | $3M | 111 mo ago | 2 | 2008 | — | — | 13 patents Metal powder production, masterbatch formulation, and metal matrix composite manufacturing | — |
| 15 | Loop CO2 Technology to convert CO2 into essential products | $2M | 47 mo ago | — | 2022 | Ian Tonks Co-Founder and Chief Science Officer | — | — | — |
| 16 | Emvolon Manufacturer of liquid chemicals | $2M | 59 mo ago | 5 | 2021 | Leslie Bromberg Co-Founder/Scientific advisor | — | — | 1 award |
| 17 | FRX Innovations Manufacturer of homo & co polymers and reactive oligomers | $1M | 39 mo ago | 13 | 2007 | Marc Lebel CEO | — | — | — |
| 18 | Multiscale Systems Manufacturer firm developing commercial applications of mechanical metamaterial technology | $1M | 14 mo ago | 8 | 2018 | Jesse Silverberg CEO | — | — | — |
| 19 | Coating Systems Provider of wet paints and powder coatings | $742K | 172 mo ago | 67 | 1992 | — | — | 475 patents Advanced high-efficiency coating formulations and application systems for abrasion and fire resistance | — |
| 20 | Optical Waters Provider of ultraviolet optical fibre solutions and other material services | $255K | 53 mo ago | — | 2020 | Katrina Fitzpatrick Co-Founder | — | — | — |
| 21 | Belmont Scientific Inc. Provider of contract research and testing services for process safety and battery technology | $225K | 80 mo ago | — | 2011 | Surendra Singh President and Founder | — | — | — |
| 22 | Leonine Technologies Provider of recruitment support and smart factory solutions, leveraging its expertise in mechanical… | $225K | 88 mo ago | — | 2019 | Rahul Panchal Founder & CEO | — | — | — |
| 23 | Material Answers Provider of consulting, engineering, and design services for polymers, ceramics & semiconductors | $200K | 47 mo ago | — | 2006 | Chris Scott Owner & President | — | — | — |
| 24 | Innovanano Provider of hydrophobic sand & perlite minerals | $200K | 155 mo ago | — | 2008 | — | — | 7 patents Hydrophobic thin‑film surface coatings via vapor‑phase deposition technologies | — |
| 25 | KaZaK Composites Manufacturer of composite structure systems | $150K | 196 mo ago | 40 | 1992 | Jerome Fanucci CEO | — | 33 patents Advanced composite structural components and pultrusion for building and defense applications | — |
Top 12 Chemicals and Materials companies in Massachusetts
#1
Public · Billerica, Massachusetts · founded 1966 · 1361 employees$1.3Braised▾
Entegris is a provider of materials handling solutions for manufacturing processes. It manufactures filtration products to purify gases and fluids, liquid systems, high-performance materials, and specialty gas management solutions, graphite, silicon carbide, and coatings. Additionally, it provides yield improving, field support services, contamination control services, refurbishment, cleaning, and analytical services to semiconductor device manufacturers.
- Jun 2024Grant (prize money)—
- Nov 2018Conventional Debt$700M
- Nov 2017Post IPO$550M
- Jun 2015Grant (prize money)$150K
#2
Seed · Somerville, Massachusetts · founded 2024$17.2Mraised▾
Developer of a subsurface process for producing ammonia from iron resources. It utilizes oil and gas techniques to inject engineered fluids. This process harnesses the chemical and thermal potential of the earth. The aim is to split water into hydrogen and oxygen. The hydrogen then reacts to produce ammonia. This production method is intended to be cheaper and less energy-intensive.
- Nov 2025Seed$8.4M
- Jan 2025Seed$4.2M
- Jan 2025Grant (prize money)$4.5M
#3
Public · Norton, Massachusetts · founded 1984 · 86 employees$14.7Mraised▾
CPS Technologies is a world leader in developing advanced materials solutions for industries such as transportation, energy, aviation, defense, and oil & gas. They specialize in metal matrix composites and thermal management solutions for power electronics and military armor. CPS Technologies reported revenue of $6.3 million for the third quarter of fiscal 2023.
- Sep 2025Grant (prize money)$123.5K
- Jul 2023Grant (prize money)$1.3M
- Jul 2011Grant (prize money)$6.6M
- Sep 2008Grant (prize money)$6.6M
#4
Funding Raised · Cambridge, Massachusetts · founded 2019 · 16 employees$23.9Mraised▾
Operator of a biotechnology firm intended to identify, neutralize, and eliminate harmful compounds to treat life-threatening conditions. The company develops new technologies and platforms to address chemical and biological weapons threats for defense applications and commercial markets, enabling soldiers with detection, decontamination, and medical countermeasures to save lives, enhancing safety on the tactical battlefield, and first responders in emergency situations, and civilians across the country.
- Apr 2025Grant (prize money)$12M
- Mar 2025Grant (prize money)$12M
#5
Funding Raised · Woburn, Massachusetts · founded 2018 · 10 employees$6.6Mraised▾
Developer of laser particle technology
- Mar 2025Grant (prize money)$1.1M
- Feb 2025Grant (prize money)$1.1M
- Feb 2024Grant (prize money)$239.7K
- Sep 2023Grant (prize money)$1.8M
#6
Funding Raised · Worcester, Massachusetts · founded 2018 · 8 employees$1.1Mraised▾
Multiscale Systems in an advanced materials firm specializing in the design, fabrication, and manufacture of mechanical metamaterials. We use geometric patterns that can be embedded into common materials, endowing this base material with new capabilities and enhanced properties. Our key advantage is we do all this without modifying the existing material chemistry, which keeps our costs low and success-rate high. For our rules on social interaction: https://multiscalesystems.com/terms-policies/terms-of-use/
- Apr 2025Grant (prize money)$206.5K
- Jul 2023Grant (prize money)$250K
- Jun 2022Grant (prize money)$200K
- Feb 2020Grant (prize money)$200K
#7
Series C · Medford, Massachusetts · founded 2013 · 101 employees$190Mraised▾
Developer of bioactive peptides derived from silk protein for skincare. These peptides are clinically proven and naturally derived. The company creates ingredients designed to improve product performance and sustainability. It offers bioactive peptides and hydrogels for healthier skin. The peptides support skin restoration after damage and UV exposure.
- Jun 2022Series C$120M
- Dec 2021Series B$70M
- Jun 2019Series A—
#8
Series C · Harvard, Massachusetts · founded 2019 · 10 employees$32Mraised▾
Provider of product development, supplier management, metrology, and engineering services
- May 2023Series C$32M
#9
Series E · Chelmsford, Massachusetts · founded 2007 · 13 employees$101.8Mraised▾
FRX Innovations is a leading global manufacturer of environmentally sustainable flame retardant solutions for a range of consumer and industrial applications. They offer a line of patent-protected products under their Nofia brand that address the problem of using halogenated flame retardants.
- Oct 2019Series E—
- Sep 2016Series D$22.6M
- May 2014Series C$8M
- Jan 2014Series C$12M
#10
Funding Raised · Lexington, Massachusetts · founded 2002 · 75 employees$32.3Mraised▾
Developer of functional wearables and functional coatings for various applications. The company develops functional clothing and protective devices through clothing designers, human factors engineers, and mechanical engineers. These teams develop products from initial concepts and prototyping to final products. The company also formulates coatings and technologies for commercial and government clients. These are used in formulated products, material substitution, and hazard detection.
- Feb 2021Grant (prize money)$400K
- Jan 2020Grant (prize money)$119.9K
- Jun 2015Grant (prize money)$149.9K
- Jun 2014Grant (prize money)$225K
#11
Funding Raised · Norwood, Massachusetts · founded 1996$22.8Mraised▾
Research and development corporation specializing in advanced materials and biomedical technology. The company converts basic research into innovative products and processes. Expertise lies in advanced materials, spectroscopic and analytical instrumentation, and biomedical technology. The company adopts a multidisciplinary approach to research, fostering collaborations with academic, government, and private research institutions. The company serves government and industrial clients worldwide, focusing on innovation and development in its core areas.
- Jul 2021Grant (prize money)$100K
- Mar 2015Grant (prize money)$981.9K
- Feb 2014Grant (prize money)$1.1M
- Feb 2013Grant (prize money)$2.4M
#12
Seed · Cambridge, Massachusetts · founded 2022 · 10 employees$3.3Mraised▾
Developer of a microbial platform designed to produce fast sustainable products from plastics to protein. The company specializes in synthetic technology to develop new microbial chassis, enabling scientists in scaling sustainable products.
- Feb 2023Seed$3.3M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Chemicals and Materials coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
What Massachusetts researches in advanced materials
MIT and UMass institutions lead Massachusetts advanced-materials research, optimistically focused on sensor, energy-harvesting, and mechanical materials, with breakthroughs dominating over concerns.
- Massachusetts Institute of Technology20
- University of Massachusetts Amherst6
- University of Massachusetts Lowell2
- Massachusetts General Hospital1
- University of Massachusetts Chan Medical School1
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.