Artificial Intelligence · San Diego, India

Best Artificial Intelligence Companies in San Diego, United States

Updated 2026-06-23 · Ranked by funding & momentum

69 indexable Artificial Intelligence companies headquartered in San Diego, United States, ranked by total equity funding and recent funding momentum. Combined disclosed equity funding of $3.1B across 27 funded companies, including 4 unicorns.

69
Companies
$3.1B
Total Funding
27
Funded
4
Unicorns
2
Rounds (90d)

Ranked: Best Artificial Intelligence companies in San Diego

#CompanyFundingValuationStage Latest roundEmployeesFoundedMomentum
1 Shield AI Unicorn
Developer of AI-powered platforms and software for defense applications
$930.2M $2.8B
as of 2023
Series G Series G Mar 2026 364 2015 ↑ Active
2 Iambic Therapeutics
Provider of AI-driven drug discovery platform for the treatment of cancer
$206.2M Series C Series C Apr 2026 50 2019 ↑ Active
3 Unconventional AI Unicorn
Developer of computer systems optimizing energy efficiency for artificial intelligence
$475M Seed Seed Dec 2025 2025 ↑ Active
4 Netradyne Unicorn
AI-powered fleet safety camera system
$217.7M Series D Series D Jan 2025 245 2015 ↑ Active
5 Model Medicines
Developer of AI-based drug discovery platform
$19.8M Series A Series A Oct 2025 26 2019 ↑ Active
6 Personal AI
Developer of AI-based personal digital AI
$7.8M Series A Series A Dec 2025 14 2020 ↑ Active
7 MemComputing
Reinventing computing with innovative solutions for complex problems and AI
$3M Series A Series A Nov 2025 9 2016 ↑ Active
8 Brain Corp
Developer of an autonomy platform for robotic and AI applications
$193.3M Series D Series D Feb 2024 242 2009
9 Kneron Unicorn
Developer of edge artificial intelligence solutions including SoCs and AI models
$226M $1B
as of 2024
Series B Series B Sep 2023 38 2015
10 TuSimple
AI-powered provider of self-driving solutions for trucks
$648M Public Post IPO Aug 2022 787 2015
11 EyePop.ai
Provider of a self-service platform for training custom AI vision models
$2.9M Seed Seed Mar 2025 5 2023 ↑ Active
12 Gretel Technologies
Provider of solutions for data anonymization
$65.5M Acquired Series B Oct 2021 19 2019
13 RapidFire
Platform for scaling of deep learning models
$4M Series A Series A Mar 2024 2024
14 Accel Robotics
Provider of AI-based automated checkout solutions for offline retailers
$35M Series A Series A Oct 2019 2 2015
15 Yembo
Provider of AI-powered virtual survey and inspection solutions for industries
$12.9M Series A Series A Apr 2021 57 2016
16 Nervana Systems
Online retailer offering diverse products, from electronics to fashion and groceries
$25M Acquired Series B Jul 2015 48 2014
17 DB CyberTech
AI-based predictive data loss prevention solution provider
$21.5M Deadpooled Series C Dec 2014 10 2012
18 Verse.ai
Customer engagement platform for businesses to connect with customers through AI powered texting
$16.5M Series A Series A Apr 2018 68 2013
19 COMMA
Tech-enabled platform offering semi-autonomous driving solutions
$8.1M Series A Series A Apr 2018 24 2015
20 Emotient
Facial expression recognition and analysis
$8M Acqui-Hired Series B Mar 2014 25 2012
21 Harvest AI
AI based data loss prevention using UBA
$2.4M Acquired Seed Apr 2019 11 2014
22 A-Life Medical
Is a provider of computer-assisted coding products and services for the healthcare industry.
$3M Acqui-Hired Series A Jun 2009 19 1996
23 Oloren AI
Provider of AI-based molecular property prediction platform for drug discovery
$300K Deadpooled Seed May 2022 10 2021
24 HumansFirst
Flexible web hosting and website creation services for all your needs
$900K Seed Seed Dec 2016 2012
25 Animantis
Next-gen computer vision for single-cell analysis, enabling better treatments
$550.2K Seed Seed Jan 2019 3 2014
26 Steno Technologies
Developer of AI twins for personalized brand and expert interactions
$20K Seed Seed 2023 2021
27 VergenceTechnologies
Full motion video and remote sensor analysis for defence and law enforcement
$50K Deadpooled Seed May 2016 2014
28 AzurEngine
Developer of a reconfigurable parallel processor
Series A Series A Feb 2024 2016
29 Point Predictive
Provider of AI-driven solutions for assessing lending risk and fraud
Series B Conventional Debt Oct 2021 42 2013
30 Trials.ai
Provider of AI based trial management solution.
Acquired Seed Nov 2019 5 2014
31 10zebra
Provider of AI-enabled, cloud-based platform for collaborative video creation and editing
Unfunded 2021
32 1859
AI-powered drug discovery platform for novel small molecule therapeutics
Deadpooled 59 2019
33 AetherLab
AI guardrails and trust solutions for generative AI applications
Unfunded 2023
34 amara health analytics
Amara Health Analytics provides real-time predictive analytics to support clinicians in the early detection of critical disease states.
Deadpooled 1 2010
35 Analyst Toolbox
AI-powered solutions transforming data into actionable knowledge and organizational intelligence
Funding Raised 2013
36 Anginax
Developer of an AI-powered assistant for cardiology and related medical fields
Unfunded 2023
37 Azyo
Provider of a neural network and computer vision-based identity verification solution
Unfunded 2020
38 Botlio AI
Provider of custom AI agents and workflow automation solutions
Unfunded 2022
39 Capture2
A revolutionary business intelligence, capture, and proposal management solution within a secure, collaborative and customizable platform.
12 2015
40 ciconia medical
Maternal health medical device
Private 2 2022
41 Client Catch
Digital Marketing That Drives More Sales. Period.
2021
42 cribsee
Cribsee develops an AI-driven search technology for the real estate industry.
Private 3 2020
43 Data4Cure
Provider of biomedical intelligence cloud and knowledge graph for drug discovery
Funding Raised 13 2013
44 Ecorithms
Provider of cloud based AI platform for waste management
Unfunded 2022
45 EcoSec Works
Developer of an AI platform for securing distributed infrastructure operations
Unfunded 2024
46 Golf AI App
Provider of an AI and camera-based swing video analytics application for golf players
Unfunded 2 2019
47 Hammer
AI-powered platform maximizing car dealership revenue through instant lead response
Unfunded 2012
48 Hillbot
Developer of embodied artificial intelligence solutions for robotic skill learning
Unfunded 2024
49 Klover
AI powered decision support platform for enterprises
Unfunded 2023
50 knowbility
AI CFO for founders and Investors
Private 1 2017

Top 12 Artificial Intelligence companies in San Diego

#1
Shield AI Unicorn Series G
$930.2M Raised
expand_more
location_onSan Diego, California
Founded
2015
Employees
364
Funding raised
$930.2M
Valuation
$2.8B · 2023
Stage
Series G

Developer of AI-powered platforms and software for defense applications. The company provides solutions for mission autonomy, surveillance, and object detection. Its offerings include autonomous pilot software, command and control toolkits, and autonomy development platforms. It also manufactures unmanned aircraft for intelligence, surveillance, and reconnaissance missions.

Funding rounds (16 disclosed of 17)
Round Date Amount
Series G Mar 2026 $2B
Series F Feb 2025 $591.8M
Series F Dec 2023 $100M
Venture Debt Dec 2023 $200M
Series F Sep 2023 $281.3M
Series E Dec 2022 $60M
11 earlier rounds — sign up free
Tech stack
anime.jsapple icloud mailcloudflarecloudflare bot managementcore-jsdocusign+14
#2
$206.2M Raised
expand_more
location_onSan Diego, California
Founded
2019
Employees
50
Funding raised
$206.2M
Stage
Series C

Provider of AI-driven drug discovery platform for the treatment of cancer. It offers an AI driven discovery platform and has discovered two candidates known as IAM-H1, a highly selective and brain penetrant inhibitor of HER2 and its oncogenic mutants, and IAM-C1 a potential first-in-class selective dual CDK2/4 inhibitor to address unmet needs in terms of therapeutic window and treatment resistance in cell cycle drive

Funding rounds (5 disclosed of 5)
Round Date Amount
Series C Apr 2026 $27.8M
Series C Nov 2025 $100M
Series B Apr 2024 $50M
Series B Oct 2023 $103.2M
Series A Jul 2021 $53M
Tech stack
apple icloud mailcloudflaredocusigngoogle font apigoogle hosted librarieshsts+8
#3
Unconventional AI Unicorn Seed
$475M Raised
expand_more
location_onSan Diego, California
Founded
2025
Funding raised
$475M
Stage
Seed

Developer of computer systems optimizing energy efficiency for artificial intelligence. The company focuses on rethinking computer foundations to manage the optimization. It combines solutions in artificial intelligence systems, analog circuits, computing theory, and neuroscience. The company aims to bring biology-scale efficiency to artificial intelligence.

Funding rounds (1 disclosed of 1)
Round Date Amount
Seed Dec 2025 $475M
Tech stack
apple icloud mailbootstrapcloudflarecloudflare bot managementgoogle analyticsgoogle tag manager+14
#4
Netradyne Unicorn Series D
$217.7M Raised
expand_more
location_onSan Diego, California
Founded
2015
Employees
245
Funding raised
$217.7M
Stage
Series D

AI-powered fleet safety camera system. It uses computer vision and edge computing to monitor driver behavior and reduce accidents in real-time. It combines multi-camera hardware with proprietary AI analyzing driving time to detect drowsiness, tailgating, distractions, and reward safe driving via DriverStars.

Funding rounds (6 disclosed of 6)
Round Date Amount
Series D Jan 2025 $90M
Conventional Debt Sep 2022 $65M
Series C Jul 2021 $150M
Series B Nov 2019 $20.2M
Series B Sep 2018 $21M
Series A Jun 2016 $16M
Tech stack
amazon sesamazon web servicesangularangularjsapache http serverappcues+14
#5
Model Medicines Series A
$19.8M Raised
expand_more
location_onSan Diego, California
Founded
2019
Employees
26
Funding raised
$19.8M
Stage
Series A

Developer of AI-based drug discovery platform. The company focuses on therapeutics for gastric disorders, neurological disorders, weight disorders, and infectious diseases. Also, uses the collection of drug development data, a drug and disease agnostic discovery platform along with AI to develop drugs.

Funding rounds (6 disclosed of 6)
Round Date Amount
Series A Oct 2025 $3.3M
Series A Sep 2024 $14.8M
Series A Dec 2023 $950K
Series A Apr 2022 $489K
Series A Nov 2021 $4.1M
Series A Aug 2020 $3.5M
Tech stack
cloudflarecloudflare bot managementcore-jsframer sitesgoogle analyticsgoogle font api+10
#6
Personal AI Series A
$7.8M Raised
expand_more
location_onSan Diego, California
Founded
2020
Employees
14
Funding raised
$7.8M
Stage
Series A

Developer of AI-based personal digital AI. It uploads and trains personal AI on all historical memories, knowledge, and experiences in order to create utility and value from data.

Funding rounds (2 disclosed of 3)
Round Date Amount
Series A Dec 2025 $14.1M
Seed Sep 2024 Undisclosed
Seed Nov 2022 $7.8M
Tech stack
amazon web servicesapple icloud mailcloudflaredidomienvoygoogle font api+14
#7
MemComputing Series A
$3M Raised
expand_more
location_onSan Diego, California
Founded
2016
Employees
9
Funding raised
$3M
Stage
Series A

Reinventing computing with innovative solutions for complex problems and AI. They are redefining what's possible in the computing landscape. They offer products and resources designed to break bottlenecks and solve complex problems faster. Their core focus is on developing real technology, particularly in the realm of Artificial Intelligence. They are committed to sustainability, designing chips that run cool and con

Funding rounds (1 disclosed of 3)
Round Date Amount
Series A Nov 2025 $4.4M
Seed Jul 2020 Undisclosed
Seed Jun 2019 Undisclosed
Tech stack
drupalphpbootstraprecaptchajquerygoogle analytics+6
#8
Brain Corp Series D
$193.3M Raised
expand_more
location_onSan Diego, California
Founded
2009
Employees
242
Funding raised
$193.3M
Stage
Series D

Developer of an autonomy platform for robotic and AI applications. The platform empowers organizations to automate and infuse intelligence into core operations. It provides solutions for automated inventory management, floor care, and remote site management. The company offers robotic and AI solutions for smarter, more productive operations across various industries.

Funding rounds (4 disclosed of 5)
Round Date Amount
Series D Feb 2024 $32.1M
Series D Apr 2020 $36.2M
Series C Jul 2017 $114M
Series B Sep 2012 Undisclosed
Series B $11M
Tech stack
apple icloud mailcloudflarecloudflare bot managementcore-jsdocusignelementor+14
#9
Kneron Unicorn Series B
$226M Raised
expand_more
location_onSan Diego, California
Founded
2015
Employees
38
Funding raised
$226M
Valuation
$1B · 2024
Stage
Series B

Developer of edge artificial intelligence solutions including SoCs and AI models. The company provides systems on chip, neural processing units, and visual recognition solutions. These solutions are designed for smart vehicles, security devices, smart homes, and edge servers. The company's technology supports mainstream AI frameworks and CNN models.

Funding rounds (9 disclosed of 10)
Round Date Amount
Series B Sep 2023 $49M
Series B Aug 2023 $14M
Series B Oct 2022 $48M
Series B Dec 2021 $25M
Series A May 2021 $7M
Series A Mar 2021 $10M
4 earlier rounds — sign up free
Founders & key people
Tech stack
amazon web servicesapache http serveraws certificate managercart functionalitycloudflarecloudflare bot management+14
#10
TuSimple Public
$648M Raised
expand_more
location_onSan Diego, California
Founded
2015
Employees
787
Funding raised
$648M
Stage
Public

AI-powered provider of self-driving solutions for trucks. It develops a commercial-ready Level 4 (SAE) fully-autonomous truck driving solution for the logistics sector. Its product portfolio consists of full-stack autonomous driving technology and high-speed long-distance sensing technology. Its self-driving technology encompasses various factors of autonomy such as perception, localization, planning, HD maps, and co

Funding rounds (6 disclosed of 12)
Round Date Amount
Post IPO Aug 2022 $15M
Series E Feb 2021 Undisclosed
Series E Jan 2021 Undisclosed
Series E Nov 2020 $350M
Series D Sep 2020 Undisclosed
Series D Jul 2020 Undisclosed
6 earlier rounds — sign up free
Founders & key people
Tech stack
wordpressmysqlphpdebianamazon web servicesaddtoany share buttons+14
#11
EyePop.ai Seed
$2.9M Raised
expand_more
location_onSan Diego, California
Founded
2023
Employees
5
Funding raised
$2.9M
Stage
Seed

Provider of a self-service platform for training custom AI vision models. The platform enables users to define targets, upload data, train models, deploy solutions to the cloud or edge devices, and iterate for improvement. It offers solutions for industries like roofing, construction, insurance, and agtech, allowing them to detect, count, and measure objects in images and videos. The platform also provides pre-traine

Funding rounds (1 disclosed of 1)
Round Date Amount
Seed Mar 2025 $2.9M
Tech stack
amazon s3amazon web servicescloudflarecloudflare bot managementcore-jsfacebook pixel+14
#12
$65.5M Raised
expand_more
location_onSan Diego, California
Founded
2019
Employees
19
Funding raised
$65.5M
Stage
Acquired

Gretel provides solutions for data anonymization. The product offers APIs that integrate with developers existing workflows and tools. It also provides machine learning models that help developers make sense of their data, and to automate joining data with complementary open source datasets and private datasets.

Funding rounds (3 disclosed of 3)
Round Date Amount
Series B Oct 2021 $50M
Series A Oct 2020 $12M
Seed Mar 2020 $3.5M

Recent signals in San Diego Artificial Intelligence

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Funding & investor landscape

Total raised
$3.1B
across these companies
Companies funded
27
with disclosed funding
Highest-funded
$930.2M raised

Most active investors

EvoNexus EvoNexus 4 investments in Artificial Intelligence Andreessen Horowitz Andreessen Horowitz 3 investments in Artificial Intelligence Qualcomm Ventures Qualcomm Ventures 3 investments in Artificial Intelligence ARK Investment Management ARK Investment Management 2 investments in Artificial Intelligence DCVC DCVC 2 investments in Artificial Intelligence Deep Learning Deep Learning 2 investments in Artificial Intelligence Future Ventures Future Ventures 2 investments in Artificial Intelligence Gaingels Gaingels 2 investments in Artificial Intelligence Homebrew Homebrew 2 investments in Artificial Intelligence Lux Capital Lux Capital 2 investments in Artificial Intelligence Moonshots Capital Moonshots Capital 2 investments in Artificial Intelligence Nex Cubed Nex Cubed 2 investments in Artificial Intelligence

Notable founders in San Diego Artificial Intelligence

Brandon Tseng Brandon Tseng Co-Founder Shield AI · $930.2M raised
Ryan Tseng Ryan Tseng Co-Founder & Chief Strategy Officer & President Shield AI · $930.2M raised
Gary Steele Gary Steele CEO Shield AI · $930.2M raised
Fred Manby Fred Manby Co-Founder & CTO Iambic Therapeutics · $206.2M raised
Thomas Miller Thomas Miller Co-Founder & CEO Iambic Therapeutics · $206.2M raised
SA Sara Achour Co-Founder Unconventional AI · $475M raised
MC Michael Carbin Co-Founder Unconventional AI · $475M raised
NR Naveen Rao Co-Founder & CEO Unconventional AI · $475M raised
David Julian David Julian Co-Founder & CTO Netradyne · $217.7M raised
Avneesh Agrawal Avneesh Agrawal Co-Founder & CEO Netradyne · $217.7M raised
Kristie Sibal Kristie Sibal Co-Founder Personal AI · $7.8M raised
Sharon Zhang Sharon Zhang Co-founder & CTO Personal AI · $7.8M raised

Frequently asked questions

How many Artificial Intelligence companies are there in San Diego, United States?
Radar tracks 69 indexable Artificial Intelligence companies headquartered in San Diego, United States that meet our profile-completeness bar.
What is the total funding raised by Artificial Intelligence companies in San Diego, United States?
The Artificial Intelligence companies in San Diego, United States on this list have raised a combined $3.1B in disclosed equity funding across 27 funded companies.
Which is the highest-funded Artificial Intelligence company in San Diego, United States?
Shield AI is the highest-funded Artificial Intelligence company in San Diego, United States, with $930.2M in disclosed equity funding.
How many Artificial Intelligence companies in San Diego, United States are funded?
27 of the 69 Artificial Intelligence companies in San Diego, United States on this list have disclosed at least one equity funding round.
How many Artificial Intelligence unicorns are there in San Diego, United States?
4 Artificial Intelligence companies in San Diego, United States on this list are valued at $1B or more.
Who are the top investors in San Diego, United States Artificial Intelligence companies?
The most active investors in San Diego, United States Artificial Intelligence companies on this list include EvoNexus, Andreessen Horowitz, Qualcomm Ventures, ARK Investment Management, DCVC.

Rankings are computed by Radar (Fliar BI) from the Radar company master and are updated periodically. Funding and momentum scores use disclosed equity-funding data only. Figures may lag private rounds. Last updated 2026-06-23.

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