Best Enterprise Applications Companies in San Diego, United States
The 698 best Enterprise Applications companies in San Diego, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Seismic.
Ranked: Best Enterprise Applications companies in San Diego
| # | Company | Disclosed funding | Last round | Employees | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|
| 1 | Seismic 🦄 Provider of an AI-powered platform for sales and marketing enablement | $440M | 24 mo ago | 989 989 → 1,329 (+34%) · sector median +16% | WordPress Block EditorWordPressApple iCloud Mail+38 | 47 patents Seismic data compression/noise reduction and wearable exosuit biomechanics for rehabilitation | — |
| 2 | Human Longevity Provider of precision medicine, preventative health assessments, and longevity care | $409M | 21 mo ago | 85 | TurbopackNode.jsYouTube+23 | 71 patents AI-driven multi‑omic analytics for disease risk assessment, diagnosis, and genomic trait prediction | 1 launch · 1 partnership |
| 3 | Drata 🦄 Risk assessment and management solutions for enterprises | $328M | 42 mo ago | 393 393 → 672 (+71%) · sector median +16% | Apple iCloud MailGoogle WorkspaceNode.js+41 | 5 patents Real-time automated compliance monitoring and policy mapping for cloud security platforms. | 1 launch · 1 partnership |
| 4 | Tealium 🦄 Customer data management and orchestration platform | $277M | 64 mo ago | 353 353 → 558 (+58%) · sector median +16% | WordPressApple iCloud MailGoogle Workspace+23 | 156 patents Real-time customer data platform for visitor profiling, engagement tracking, and data integration | 1 launch |
| 5 | CloudBeds Provider of a platform for hospitality operations, distribution, and marketing | $253M | 55 mo ago | 172 | WordPressSentryZendesk+34 | — | 1 expansion |
| 6 | SOCi Marketing platform for businesses | $238M | 39 mo ago | — | WordPressMySQLPHP+33 | 20 patents Automated generation, targeting, and distribution of social media marketing communications | — |
| 7 | classy Classy offers an online and mobile platform that enables socially good organizations to raise funds for… | $183M | 62 mo ago | 493 238 → 197 (-17%) · sector median +16% | WordPress Block EditorWordPressSentry+39 | — | — |
| 8 | Kyriba 🦄 Provider of cloud-based platform for treasury, risk, payments, and working capital | $159M | 20 mo ago | 334 | SentryApple iCloud MailNode.js+25 | — | 1 partnership |
| 9 | Trackforce Valiant Provider of HR, workforce & payroll management services | $157M | 81 mo ago | 115 | — | — | — |
| 10 | Mitek Provider of AI-driven solutions for identity verification and fraud prevention | $156M | 64 mo ago | 590 590 → 765 (+30%) · sector median +16% | DrupalApple iCloud MailPHP+20 | 882 patents Automated saw and lumber processing systems for wood construction and modular building. | — |
| 11 | Housecall Pro Business management software for home service businesses | $147M | 47 mo ago | 454 | WordPressSentryMySQL+35 | — | — |
| 12 | Events.com Online platform for organizing and promoting events | $84M | 36 mo ago | 58 | SentryZendeskApple iCloud Mail+33 | — | — |
| 13 | Cordial Provider of cross-channel marketing platform with AI and data unification | $71M | 46 mo ago | 80 | WordPressMySQLPHP+40 | — | 1 partnership |
| 14 | Gretel Technologies Provider of solutions for data anonymization | $66M | 56 mo ago | 19 | WebflowApple iCloud MailGoogle Workspace+22 | 3 patents Contact management software platforms for business communication and data handling | — |
| 15 | Workiz Field services management and scheduling software | $60M | 55 mo ago | 115 | WordPressApple iCloud MailGoogle Workspace+33 | — | 1 launch |
| 16 | Givebutter Cloud-based fundraising platform for nonprofit organization | $57M | 25 mo ago | 64 | WebflowApple iCloud MailGoogle Workspace+27 | — | — |
| 17 | Trovata Provider of a platform for treasury management and cash flow automation | $57M | 48 mo ago | 104 104 → 82 (-21%) · sector median +16% | WordPressSentryApple iCloud Mail+38 | 12 patents Financial data analytics platform with NLP-driven cash forecasting and cooperative resource pooling | — |
| 18 | CMX Provider of a platform for quality, risk, and compliance management | $50M | 60 mo ago | 35 35 → 81 (+131%) · sector median +16% | HubSpot CMS HubApple iCloud MailGoogle Workspace+29 | 3 patents Advanced composite molding for reinforced structural and climbing components | — |
| 19 | Closing Data and technology service provider for estimating the closing cost of real estate transactions | $45M | 77 mo ago | 101 | — | — | — |
| 20 | ForeSee Medical Decision support solutions for healthcare professionals | $44M | 15 mo ago | 21 21 → 23 (+10%) · sector median +16% | Squarespace CommerceSquarespaceSentry+29 | — | — |
| 21 | Trust and Will Cloud based platform offering legal will planning solutions 82Patents top 12%Tech top 16%Innovation top 20%Funding top 24% All 13 signals ▾Patentstop 12% Techtop 16% Innovationtop 20% Fundingtop 24% Moattop 26% Talenttop 28% Growthtop 35% Producttop 40% AItop 45% Marketbottom 45% Globalbottom 42% Customersbottom 36% Newsbottom 18% Patents: 263 patents matched (strict assignee match) · 175 filings since 2022 vs 81 in 2017-21 Tech: 81 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 rank vs industry peers · Fliar Intelligence Index 82/100 | $40M | 13 mo ago | 24 | Amazon WebstoreContentfulSentry+48 | 263 patents Biotech patents covering viral diagnostics, stem-cell organoids, gene‑RNA therapies, and cellular immunotherapy. | 1 partnership |
| 22 | Koji Platform offering link management solutions | $36M | 52 mo ago | 10 | — | — | — |
| 23 | SupplyPro Inventory management solutions for tracking and controlling indirect materials | $35M | 86 mo ago | 74 | Windows ServerMicrosoft ASP.NETBootstrap+7 | 34 patents Smart automated inventory control using electronic shelf labels and modular storage systems. | — |
| 24 | Mogl Provider of programmatic advertising, retail media activation, and data enablement services | $35M | 130 mo ago | 27 | Webflow EcommerceWebflowGSAP+17 | — | — |
| 25 | Clearspeed Provider of AI and voice-based risk assessment platform | $27M | 11 mo ago | 100 | WordPressMySQLPHP+25 | 2 patents Audio sample quality control and assessment in digital sound processing | — |
| 26 | SendLane Cloud-based platform offering marketing suite to enterprises | $23M | 58 mo ago | 49 | WebflowSentryLinkedin Insight Tag+19 | — | — |
| 27 | eSUB Cloud-based construction management suite solutions | $22M | 37 mo ago | 53 53 → 32 (-40%) · sector median +16% | Apple iCloud MailMicrosoft 365TypeScript+26 | — | 2 launchs |
| 28 | Daasity Provider of data analytics platform for e-commerce and retail brands | $21M | 53 mo ago | 31 31 → 37 (+19%) · sector median +16% | WebflowMarkerApple iCloud Mail+27 | — | 2 launchs |
| 29 | CourseKey School management solutions provider 37Customers top 19%Funding top 31%Moat top 39%Product top 46% All 8 signals ▾Customerstop 19% Fundingtop 31% Moattop 39% Producttop 46% Talentbottom 49% Growthbottom 41% Marketbottom 40% Globalbottom 37% Customers: App rating 4.7★ (1,338 reviews) · Review volume +8% in 6 mo Funding: Raised $20.0M across 4 rounds · 4 rounds over 10 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 37/100 | $20M | 17 mo ago | 34 | — | — | — |
| 30 | Payroll Integrations Provider of payroll management solutions for enterprises | $20M | 31 mo ago | 21 | HubSpot CMS HubApple iCloud MailGoogle Workspace+20 | — | — |
| 31 | Tiled Conversational platform for field and sales teams | $18M | 33 mo ago | 35 35 → 40 (+14%) · sector median +16% | WebflowApple iCloud MailGoogle Workspace+25 | — | 1 launch |
| 32 | Learnsoft Cloud-based LMS for the multi industry | $17M | 45 mo ago | 36 | Webflowlit-htmlcore-js+16 | — | — |
| 33 | GoFormz Mobile businesses productivity platform by digitializing paper forms | $16M | 60 mo ago | 62 62 → 63 (+2%) · sector median +16% | Apple iCloud MailGoogle WorkspacePHP+27 | 12 patents Digital paper‑form conversion and electronic data capture for workflow automation. | 2 launchs · 1 expansion |
| 34 | JUNO Provider of a platform for community engagement, learning, and virtual events | $14M | 48 mo ago | 60 | — | 42 patents Advanced waste recycling processing systems for shredding, washing, odor control, and baling | — |
| 35 | Mapp Customer engagement and marketing solution for businesses | $13M | 14 mo ago | 450 | WordPressPleskApple iCloud Mail+25 | — | — |
| 36 | Walla Provider of software for managing fitness studios and optimizing profitability | $13M | 47 mo ago | 42 | Webflow EcommerceWebflowApple iCloud Mail+23 | — | — |
| 37 | Serenity EHS Platform that provides cloud based EHS management solutions | $11M | 20 mo ago | 21 | — | — | — |
| 38 | FutureProof Online climate risk analytics platform for institutions | $10M | 49 mo ago | 23 | — | — | — |
| 39 | GroupSolver Online platform for Market research and collective problem solving | $9M | 40 mo ago | 48 | WordPressApple iCloud MailMicrosoft 365+37 | 3 patents Automated generation of group decision and optimization solutions using AI algorithms. | 1 launch |
| 40 | AvantGen Antibody discovery and engineering company advancing antibody drugs for scientific partners | $8M | 10 mo ago | 11 | — | 16 patents Therapeutic peptide ligands targeting immune receptors and SARS‑CoV‑2 viral proteins | — |
| 41 | Deckard AI-driven market intelligence solutions for real estate professionals | $7M | 37 mo ago | 64 | SentryMUITailwind CSS+15 | — | — |
| 42 | Pack Digital Provider of a platform for creating and personalizing shopping experiences | $6M | 42 mo ago | 42 | — | — | — |
| 43 | Sequence Online video creation platform | $6M | 33 mo ago | 5 | Node.jsRadix UIReact+11 | 12 patents Advanced supportive, traction footwear and mats using multi‑column layered structures | — |
| 44 | HelloSky AI executive recruiting platform | $6M | 13 mo ago | — | — | — | — |
| 45 | TrueTickets Provider of secure digital ticket delivery and audience data solutions | $5M | 18 mo ago | 21 | HubSpot CMS HubLazySizescore-js+16 | — | 1 launch · 6 partnerships |
| 46 | EP Analytics HPC experts providing performance analysis and optimization software and services | $5M | 14 mo ago | 12 | — | 56 patents Distributed asynchronous data transfer and multi-view analytics visualization platforms | — |
| 47 | PINS Advantage Insurance risk management software | $2M | 34 mo ago | 11 | — | — | — |
| 48 | Athyna Provider of recruitment platform for multiple industries | $2M | 22 mo ago | 82 | WebflowAmazon Web ServicesVWO+30 | — | — |
| 49 | S-3 Provider of research as a service using data-driven solutions | $796K | 8 mo ago | 9 | — | — | — |
| 50 | Sided Polling software for websites to collect data and optimize ad revenue | $175K | 5 mo ago | 12 | Node.jsReactNext.js+23 | — | — |
Top 12 Enterprise Applications companies in San Diego
#1
Series B · San Diego, California · founded 2013 · 85 employees$408.7Mraised▾
Provider of precision medicine, preventative health assessments, and longevity care. The company offers comprehensive health assessments to detect life-threatening conditions early. It focuses on data-driven, personalized healthcare designed to uncover health risks. The company provides services to help individuals take control of their health.
- Aug 2024Series B$39.8M
- Mar 2023Series B$32M
- Oct 2022Series B$6.9M
- Jul 2019Series B$30M
#2
Series C · San Diego, California · founded 2017 · 24 employees$39.5Mraised▾
Cloud based platform offering legal will planning solutions. The platform enables users to create and manage wills and forms to solve legal issues. It allows users to fill the questionnaire and access the forms. It also helps families in creating personal wills. It is available on subscription based pricing model.
- Apr 2025Series C$4.5M
- Mar 2025Series C$25M
- Jan 2024Series B—
- Feb 2023Series B$15M
#3
Kyriba 🦄Acquired · San Diego, California · founded 2000 · 334 employees$158.7Mraised▾
Provider of cloud-based platform for treasury, risk, payments, and working capital. The platform unifies enterprise data and automates liquidity, moving and controlling it. It increases financial resilience by reducing risk exposures and improving business continuity. The platform forecasts cash, liquidity, and risk exposures with accuracy. It helps make data-driven liquidity decisions when managing investments.
- Oct 2024Series E—
- Sep 2017Series E$45M
- Dec 2016Series D—
- Aug 2016Series D$23M
#4
Series D · San Diego, California · founded 2016 · 100 employees$27Mraised▾
Provider of AI and voice-based risk assessment platform. It provides a platform that supports businesses in voice analytics to track risks and alert users on possible fraud. It offers data to its users to support customer experience. It leverages AI technology for identifying conversational fraud analysis. It also provides tools for identifying financial fraud, security risks, IP theft prevention, supply chain compliance, transaction or individual vetting, and more.
- Jun 2025Series D$60M
- Oct 2022Series C$27M
#5
Series B · San Diego, California · founded 2017 · 21 employees$43.9Mraised▾
Decision support solutions for healthcare professionals. The solutions offered by the company include ForeSee ESP, Rule Builder, ForeSee Predictor, ForeSee Quality Director, ForeSee Analyzer, risk stratification tool, and communicator.
- Feb 2025Series B$2M
- Apr 2024Series B$4.9M
- Feb 2024Series A$500K
- Apr 2023Series A$4M
#6
Funding Raised · San Diego, California · founded 2006 · 11 employees$7.8Mraised▾
Antibody discovery and engineering company advancing antibody drugs for scientific partners. They enable the discovery and optimization of novel antibody drugs, focusing on providing partners with what they need for the next stage of development. They offer a range of platforms, including AvantEpee, AvantSabre, AvantFoil, AvantGeneer, and AvantBunny, leveraging yeast display technology and a Germliner Library Collection to generate fully human antibodies with favorable properties. They also provide services for optimizing lead candidates and developing nonhuman reagent or diagnostic antibodies. Their expertise extends to licensing opportunities, such as their Natural Killer (NK) cell engager platform. They are dedicated to pioneering research and development in antibody therapeutics, with a focus on enhancing health and wellness.
- Aug 2025Grant (prize money)$2M
- Sep 2024Grant (prize money)$1.4M
- Sep 2015Grant (prize money)$224.7K
- Sep 2014Grant (prize money)$188.1K
#7
Seismic 🦄Series G · San Diego, California · founded 2010 · 989 employees$440Mraised▾
Provider of an AI-powered platform for sales and marketing enablement. The platform offers content management, learning and coaching, and program strategy and execution. It also provides meeting intelligence, digital sales rooms, and AI capabilities. The platform aims to drive revenue, increase efficiency, and improve customer experience for teams.
- Jun 2024Conventional Debt$500M
- Aug 2021Series G$170M
- Sep 2020Series F$92M
- Dec 2018Series E$100M
#8
Series B · San Diego, California · founded 2015 · 34 employees$20Mraised▾
School management solutions provider. It offers various solutions such as time and attendance automation, digital assessments & evaluations, online learning communities, and ebook resources among others. Features include real-time insights on data, student analysis, and integration of LMS with the system.
- Jan 2025PE—
- Dec 2023Conventional Debt—
- Mar 2021Series B$9M
- Jul 2019Series A$5M
#9
Acquired · San Diego, California · founded 1999 · 450 employees$13Mraised▾
Mapp offers customer engagement and marketing solutions to businesses. Offers data aggregation, customer segmentation, campaign design, email marketing, customer intelligence, and cross-channel orchestration on one platform. Allows businesses to run marketing campaigns on email, mobile, web, and social media, with all data being centralized. The clients include Argos, flaconi, JYSK, etc.
- Mar 2025Unattributed$13M
#10
Funding Raised · San Diego, California · founded 2009 · 12 employees$4.6Mraised▾
HPC experts providing performance analysis and optimization software and services. The company delivers industry-leading expertise and software for application-focused performance analysis of cutting-edge supercomputer systems. Dedicated to helping clients understand application performance, make informed HPC procurement decisions, and maximize the efficiency of existing HPC resources. They offer HPC code modernization and optimization, cloud migration services, and performance profiling tools. SimplifyHPC streamlines computational chemistry workflows. They provide HPC procurement support, cloud HPC solutions, and HPC code services. The company develops software tools for application-focused performance prediction and energy management of high-performance computing systems. They specialize in high-performance computing, performance prediction, energy-efficient computing, software development, and computer systems research.
- Mar 2025Grant (prize money)$1.9M
- Feb 2021Grant (prize money)$1.9M
- Feb 2020Grant (prize money)$191.6K
- Feb 2017Grant (prize money)$225.7K
#11
Seed · San Diego, California · founded 2020$5.5Mraised▾
AI executive recruiting platform. It helps to find and connect with growth driven talent. It offers AI-driven features like Smart Tags, which provide insights into factors such as revenue scale, and recruitability scoring, optimizes talent acquisition.
- Apr 2025Seed$5.5M
#12
Funding Raised · San Diego, California · founded 2018 · 9 employees$795.7Kraised▾
Provider of research as a service using data-driven solutions. The company offers data collection, advanced data analysis, and custom data visualization. It delivers interdisciplinary research solutions, including digital health application development. The company uses machine learning, deep learning, and statistical analysis.
- Sep 2025Grant (prize money)$499.8K
- May 2025Grant (prize money)$295.9K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Enterprise Applications coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.