Best Genomics Companies in San Diego, United States
The 180 best Genomics companies in San Diego, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Human Longevity.
Our analysis of 50 Genomics companies
$7.8b in tracked funding; 84% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Genomics companies in San Diego
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Human Longevity Provider of precision medicine, preventative health assessments, and longevity care | $409M | 21 mo ago | 85 | J Venter Co-Founder & CEO | TurbopackNode.jsYouTube+23 | Top 5M | 71 patents AI-driven multi‑omic analytics for disease risk assessment, diagnosis, and genomic trait prediction | 1 launch · 1 partnership |
| 2 | Singlera Genomics Developer of next generation sequencing by methylation haplotyping approach for the detection of cancer | $380M | 66 mo ago | 18 | Yuan Gao Co-Founder & Chairman | — | — | 32 patents Patents concentrated in chemistry & materials | — |
| 3 | Ambrx Developer of Antibody drug conjugates to treat cancers, metabolic disorders and cardiovascular disorders | $346M | 67 mo ago | 79 | Lawson Macartney President & Ceo | WordPressBugHerdMySQL+26 | Top 10M | 1,276 patents Protein engineering and antibody-drug conjugates for therapeutic biologics | — |
| 4 | Poseida Therapeutics Developer of gene therapies for treating cancer and liver orphan disease by using gene editing technologies | $324M | 34 mo ago | 259 | — | WordPressMySQLPHP+18 | Top 10M | 426 patents Patents concentrated in chemistry & materials | — |
| 5 | ADARx Pharmaceuticals Developer of genetic therapeutic solutions to edit single point mutations on RNA transcripts | $286M | 34 mo ago | 44 44 → 95 (+116%) | Zhen Li Co-Founder & CEO | — | — | 152 patents RNA‑based therapeutics and enzyme modulation for neurodegenerative disease treatment | 5 job openings |
| 6 | Aspen Neuroscience Provider of genomic-based personalised pluripotent stem cell therapy 64Funding top 17%Patents top 23%Moat top 28%Innovation top 33% All 10 signals ▾Fundingtop 17% Patentstop 23% Moattop 28% Innovationtop 33% Growthtop 35% Newstop 45% Marketbottom 49% Talentbottom 49% Techbottom 46% Globalbottom 45% Funding: Raised $224M across 5 rounds · 5 rounds over 7 yrs (0.7/yr) Patents: 57 patents matched (strict assignee match) · 51 filings since 2022 vs 6 in 2017-21 rank vs industry peers · Fliar Intelligence Index 64/100 | $224M | 6 mo ago | 94 | Damien Mcdevitt President | WordPress Block EditorWordPressMySQL+19 | Top 10M | 57 patents Patents concentrated in computing, sensing & instrumentation | — |
| 7 | Biora Therapeutics Provider of non invasive prenatal genomic testing | $217M | 61 mo ago | 125 | Harry Stylli CEO and Chairman of the Board | — | — | — | — |
| 8 | Astute Medical Pioneering diagnostics to improve global health through innovative solutions | $207M | 114 mo ago | 51 | — | — | — | 769 patents Renal injury biomarkers and diagnostic/therapeutic assays for acute kidney disease | 1 launch · 1 award |
| 9 | Epic Sciences Provider of non-invasive tests for the detection of circulating tumor cells | $204M | 38 mo ago | 98 | — | — | — | 145 patents Liquid biopsy technologies for detecting and profiling circulating tumor cells in cancer. | — |
| 10 | Millenium Health Systems Drug testing laboratory empowering clinicians with comprehensive data insights for patient care | $196M | 190 mo ago | 484 | — | WordPressApple iCloud MailMySQL+24 | Top 5M | — | — |
| 11 | Turnstone Biologics Developer of oncolytic viral immunotherapies for cancer treatment | $172M | 59 mo ago | 80 | John Bell Co-Founder | WordPress Block EditorWordPressApple iCloud Mail+19 | Top 50M | 61 patents Engineered tumor-infiltrating lymphocytes and ex vivo T‑cell expansion for cancer immunotherapy | — |
| 12 | Denovo Biopharma Developer of genomic biomarker discovery platform | $172M | 66 mo ago | 42 42 → 28 (-33%) | — | — | — | 50 patents Predictive biomarkers and assays for nucleic‑acid therapeutics and neuro‑transporter drug efficacy | — |
| 13 | Omniome Provider of genome sequencing platform | $160M | 78 mo ago | 164 | — | — | — | 267 patents High-throughput nucleic acid sequencing, analysis, and engineered polymerase technologies | — |
| 14 | Locana Developer of CRISPR enabled RNA editing for gene therapy | $155M | 37 mo ago | 68 | Jeffrey Ostrove -CEO & Director | — | — | 11 patents RNA-targeted CRISPR/Cas fusion therapeutics for gene knockdown, replacement, and immunomodulation | — |
| 15 | Mirati Therapeutics Developer of therapeutic solutions for the treatment of cancer | $153M | 129 mo ago | 587 | — | — | — | 713 patents Targeted small‑molecule inhibitors and combos for KRAS‑mutant and related oncogenic pathways | — |
| 16 | Expansion Therapeutics Provider of a software system for the development of drugs | $140M | 56 mo ago | 20 | Matthew Disney Co-Founder | — | — | — | — |
| 17 | OmeCare Provider of genetic testing kits for fitness, and nutrition management | $130M | 125 mo ago | 22 | — | — | — | — | — |
| 18 | Bionano Provider of genome analysis solutions to researchers and clinicians | $124M | 24 mo ago | 364 | Erik Holmlin President & CEO | WordPressMySQLPHP+25 | Top 5M | 43 patents Iron‑based nanomaterials and nanoemulsion formulations for pharmaceutical delivery | — |
| 19 | Tocagen Developer of gene therapies for the treatment of cancer | $124M | 105 mo ago | 1 | — | — | — | 161 patents Gene therapy and CAR‑T delivery vectors with cytosine deaminase prodrug activation | — |
| 20 | DTx Pharma Provider of RNA-based therapeutics for multiple health purposes | $113M | 63 mo ago | 50 | — | — | — | — | — |
| 21 | Ignyta Personalized medicine for cancer and autoimmune diseases | $97M | 104 mo ago | 30 | Gary Firestein Co-Founder | — | — | 240 patents Small‑molecule kinase inhibitors for oncology, notably entrectinib and related cancer drugs | — |
| 22 | AltheaDx Molecular biomarker discovery, assay development and validation, clinical trial testing and companion… | $95M | 66 mo ago | 12 | — | — | — | 6 patents Molecular diagnostics and bioinformatics for gene expression, degraded nucleic acids, and single‑cell profiling | — |
| 23 | Sequenom Provider of noninvasive prenatal testing using circulating cell-free fetal nucleic acids | $85M | 132 mo ago | 524 | — | — | — | 1,144 patents Non‑invasive prenatal cfDNA testing for fetal genetic and chromosomal abnormalities | — |
| 24 | Synthorx Provider of solutions for drug discovery, diagnostics, and vaccines using a synthetic DNA base pair | $79M | 97 mo ago | 50 | Floyd Romesberg Founder | — | — | 299 patents Engineered cytokine conjugates and synthetic biology tools for therapeutic protein production | — |
| 25 | Molecular Assemblies Provider of an enzymatic DNA synthesis product for researchers | $78M | 51 mo ago | 21 | — | — | — | 91 patents Automated synthesis of DNA/RNA using reusable initiators and engineered enzymes | — |
| 26 | PetDx Developer of liquid biopsy technology for detection of cancer in dogs | $72M | 57 mo ago | 102 | Daniel Grosu Co-Founder & CEO | — | — | 11 patents Liquid biopsy fragmentomics for cancer detection and monitoring, including mitochondrial DNA analysis | — |
| 27 | ClearNote Health Developer of non-invasive cancer detection methods 40Moat top 22%Funding top 36%Market top 50%Talent bottom 49% All 5 signals ▾Moattop 22% Fundingtop 36% Markettop 50% Talentbottom 49% Globalbottom 36% Moat: Editorial + unicorn rating 8/10 · Soonicorn Funding: Raised $70.0M across 2 rounds · 2 rounds over 5 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 40/100 | $70M | 0 mo ago | 45 | Dave Mullarkey Chief Executive Officer | — | — | — | — |
| 28 | GenomeDx Biosciences Genomic tests for urologic cancers | $70M | 73 mo ago | 159 | — | — | — | — | — |
| 29 | OncoSec Medical Developer of intratumoral immunotherapies to harness the body's immune system to fight cancer | $69M | 90 mo ago | 26 | — | — | — | 148 patents Cancer immunotherapy response biomarkers and electroporation-based gene delivery technologies. | — |
| 30 | Biological Dynamics Provider of molecular diagnostics plaform | $68M | 67 mo ago | 54 | — | Cart FunctionalitySquarespace CommerceSquarespace+20 | Top 50M | 78 patents Biomedical diagnostics and biomarker detection, analyte data processing, dielectric materials, surface functionalization | — |
| 31 | Biocept Developer of personalized cancer diagnosis through liquid biopsy | $59M | 106 mo ago | 165 | — | — | — | 208 patents Liquid biopsy technologies for circulating tumor cell capture and nucleic acid analysis. | — |
| 32 | Actio Biosciences Developer of genetics-led therapies targeting shared biology between rare, common diseases | $55M | 12 mo ago | 21 | David Goldstein Co-Founder & CEO | WordPress Block EditorWordPressMySQL+9 | Top 10M | — | 1 job opening |
| 33 | Replay Provider of genomic reprogramming platform for writing and delivering big DNA | $55M | 42 mo ago | 13 13 → 30 (+131%) | Ron Weiss Co-Founder | ContentfulApple iCloud MailMicrosoft 365+13 | Top 50M | 46 patents Patents concentrated in chemistry & materials | — |
| 34 | 1859 Provider of DNA encoded libraries for drug discovery and development | $50M | 55 mo ago | 73 | Devon Cayer Co-Founder & CEO | — | — | 30 patents High-throughput microfluidic bioassay platforms for drug and biomolecule screening | — |
| 35 | Electronic Bio Provider of nanotech-based DNA sequencing solutions 10Funding top 37%Talent bottom 45%Global bottom 29%Market bottom 24% All 5 signals ▾Fundingtop 37% Talentbottom 45% Globalbottom 29% Marketbottom 24% Techbottom 15% Funding: Raised $40.7M across 49 rounds · 49 rounds over 19 yrs (2.6/yr) Talent: 1 named leader on record rank vs industry peers · Fliar Intelligence Index 10/100 | $41M | 12 mo ago | 15 | Eric Ervin President and CEO | — | — | — | — |
| 36 | VedaBio Provider of molecular detection and editing platform using CRISPR Cascade technology | $40M | 32 mo ago | — | Anurup Ganguli Co-Founder & CEO | WebflowThree.jsSwiper+12 | Top 50M | 63 patents Design and delivery of engineered nucleic‑acid cascade circuits for therapeutic and diagnostic applications | — |
| 37 | Regulus Therapeutics Innovative medicines company reimagining medicine to improve and extend people’s lives | $35M | 27 mo ago | 30 | — | WordPressMySQLPHP+11 | Top 5M | 403 patents Antisense oligonucleotide therapeutics for polycystic kidney disease and neurological disorders | — |
| 38 | Zafrens Provider of single-cell multi-omics analysis platform for researchers | $29M | 16 mo ago | 19 19 → 30 (+58%) | Yi Zhang Co-Founder & EVP of Engineering | — | — | 6 patents Patents concentrated in computing, sensing & instrumentation | — |
| 39 | TriLink BioTech Developer of nucleic acid and mRNA products for research applications | $29M | 15 mo ago | 348 | — | Cart FunctionalityMagentoApple iCloud Mail+38 | Top 5M | — | 3 launchs · 1 expansion · 1 award |
| 40 | Function Oncology Developer of therapeutics to treat cancer | $28M | 38 mo ago | 16 | Christian Schmedt Co-Founder | — | — | 9 patents Functional genomic profiling of cancers using CRISPR-based personalized screening | — |
| 41 | Telesis Bio Online platform offering life sciences reagents and kits | $25M | 36 mo ago | 125 | Todd Nelson CEO | WordPressApple iCloud MailMySQL+29 | Top 10M | — | 1 job opening · 3 launchs |
| 42 | Rejuvenate Bio Developer of gene therapies for treating chronic and age-related diseases | $15M | 23 mo ago | 39 | Noah Davidsohn Co-Founder & CSO | Cart FunctionalitySquarespace CommerceSquarespace+12 | Top 10M | — | — |
| 43 | Navega Therapeutics Developer of gene therapy products for chronic pain management | $15M | 13 mo ago | 10 | Prashant Mali Co-Founder | — | — | — | — |
| 44 | Eclipse Bio Developer of cell-free immunoassay | $14M | 7 mo ago | 14 | Eric Van Nostrand Co-Founder | WordPressMySQLMariaDB+25 | Top 10M | — | 1 award |
| 45 | CRISPR QC Provider of real-time CRISPR gene editing analysis. It offers solutions for measuring RNP formation, DNA… | $12M | 29 mo ago | 12 | Ross Bundy Chief Executive Officer | WordPressMySQLPHP+21 | Top 50M | — | — |
| 46 | Alida Biosciences Provider of technology for RNA analysis to improve human health | $12M | 15 mo ago | 16 | Byron Purse Co-Founder | Cart FunctionalityWooCommerceWordPress+24 | Top 10M | — | 1 internship |
| 47 | Visgenx Developer of gene therapy for age related muscular degeneration | $9M | 36 mo ago | 9 | Marty Emanuele Co-Founder & CSO | — | — | 16 patents ELOVL2-based gene therapy vectors for treating ocular diseases | — |
| 48 | Renova Therapeutics Developer of gene therapies for congestive heart failure and type 2 diabetes | $8M | 22 mo ago | 7 | Jack Reich Chief Executive Officer | WordPressMySQLPHP+17 | Top 50M | — | — |
| 49 | Arima Genomics Developer of technologies for genome sequence and structure | $7M | 11 mo ago | 48 | — | WordPressMySQLPHP+31 | Top 10M | 29 patents Patents concentrated in chemistry & materials | 1 partnership · 1 award |
| 50 | Defined Bioscience Developer of cell culture reagents, growth medium, and kits for cell-based assays | $2M | 14 mo ago | 6 | Steven Rees Founder & CEO | Cart FunctionalityShopifyShop Pay+17 | Top 10M | — | 1 partnership |
Top 12 Genomics companies in San Diego
#1
Series D · San Diego, California · founded 2016 · 45 employees$70Mraised▾
Developer of non-invasive cancer detection methods. It offers a 5-hydroxymethylcytosine-based epigenomic platform and cell-free DNA-based assays to measure biological changes in cells and detect cancers with high mortality rates when they respond best to treatment.
- May 2025Series C$21.8M
- May 2021Series C$70M
#2
Series C · San Diego, California · founded 2018 · 94 employees$224Mraised▾
Provider of genomic-based personalized pluripotent stem cell therapy. It offers regenerative cell treatment like dopaminergic neurons for Parkinson's disease and other neurological disorders. It maintains the genetic-based quality control to avoid the mutation of cells used for therapy.
- Nov 2025Series C$115M
- Dec 2022Conventional Debt$40M
- May 2022Series B$147.5M
- Apr 2020Series A$70M
#3
Series B · San Diego, California · founded 2013 · 85 employees$408.7Mraised▾
Provider of precision medicine, preventative health assessments, and longevity care. The company offers comprehensive health assessments to detect life-threatening conditions early. It focuses on data-driven, personalized healthcare designed to uncover health risks. The company provides services to help individuals take control of their health.
- Aug 2024Series B$39.8M
- Mar 2023Series B$32M
- Oct 2022Series B$6.9M
- Jul 2019Series B$30M
#4
Series A · San Diego, California · founded 2017 · 14 employees$14Mraised▾
Developer of cell-free immunoassay. The company have developed an eCLIP-seq method (high-throughput sequencing) which increases crosslinking and immunoprecipitation. It helps to identify RNA binding protein targets. The main components of each eCLIP include cancer cell line (HEK293T, K562), stem cells (human iPSC), differentiated stem cells (neurons, cardiomyocytes), and tissues (brain, heart).
- Nov 2025Series A$4.9M
- Apr 2025Grant (prize money)$1.4M
- Jan 2025Grant (prize money)$1.4M
- Jul 2024Grant (prize money)$1.4M
#5
Series B · San Diego, California · founded 2021 · 21 employees$55Mraised▾
Developer of genetics-led therapies targeting shared biology between rare, common diseases. It applies expertise in genetics, drug discovery, and data sciences. The focus is on pinpointing targets that cause rare diseases. The aim is to enhance understanding of both the target and disease. The approach guides therapeutic expansion to more prevalent diseases.
- Jun 2025Series B$66M
- Sep 2023Series A$55M
#6
Funding Raised · San Diego, California · founded 2002 · 15 employees$40.7Mraised▾
Provider of nanotech-based DNA sequencing solutions. It offers systems for ion channel characterization, and chemical sensing and develops systems for nanopore and ion channel measurements. The instruments developed by the company aids with applications in DNA sequencing, ion channel characterization, and chemical sensing.
- May 2025Grant (prize money)$400K
- May 2025Grant (prize money)$350K
- Apr 2025Grant (prize money)$350K
- Mar 2025Grant (prize money)$386.5K
#7
Acquired · San Diego, California · founded 1996 · 348 employees$28.7Mraised▾
Develoeper of nucleic acid and mRNA products for research applications. The company offers a comprehensive product catalog focused on nucleic acids, mRNA reagents, and related tools for research, diagnostics, and therapeutics. It categories include nucleoside triphosphates (NTPs), modified nucleotides, capping analogs, enzymes, and kits.
- Mar 2025Grant (prize money)$12.7M
- Mar 2025Grant (prize money)$12.7M
- Jan 2015Grant (prize money)$132.8K
- Feb 2013Grant (prize money)$132.8K
#8
Funding Raised · San Diego, California · founded 2018 · 10 employees$14.5Mraised▾
Developer of gene therapy products for chronic pain management. The company's novel gene therapy platform to target and imitate the patients with a mutation in the genome where no pain is felt., and apply it to treat pain.
- Apr 2025Grant (prize money)$4.3M
- Apr 2025Grant (prize money)$4.3M
- Apr 2025Grant (prize money)$2.2M
- Sep 2023Grant (prize money)$400K
#9
Series C · San Diego, California · founded 2015 · 48 employees$7Mraised▾
Developer of technologies for genome sequence and structure. Arima Genomics is developing a novel method of DNA sequencing that enables genome-scale phasing or haplotyping of DNA variants using a combination of proximity ligation (Hi-C), short-read DNA sequencing, and a proprietary probabilistic algorithm for haplotype assembly. The company calls its new method, HaploSeq, and is derived from work done by Selvaraj et al (Nature Biotechnology, 2013, Vol 31, pp-1111). The method addresses a currently unmet need for cost-effective and reliable methods for the phasing of variants. Arima has multiple SIBR grants from the Department of Health and human services to develop their method.
- Jun 2025Series C$22M
- Feb 2023Grant (prize money)$2.1M
- Mar 2022Series B$7M
- Sep 2021Grant (prize money)$2.1M
#10
Series A · San Diego, California · founded 2021 · 19 employees$29.2Mraised▾
Provider of single-cell multi-omics analysis platform for researchers. The company specializes in building tools and generating insights at the interface of biology, chemistry, and engineering. It offers multi-omic assays and the study of mechanistic insights into the RNA regulatory layer.
- Feb 2025Series A—
- Dec 2023Series A$23M
- Jan 2022Series A$6.2M
#11
Series A · San Diego, California · founded 2020 · 16 employees$11.5Mraised▾
Provider of technology for RNA analysis to improve human health. The company offers new technologies in RNA biology to develop new medical treatments and diagnostic assays.
- Mar 2025Grant (prize money)$1.7M
- Jun 2024Series A$7.5M
- May 2023Grant (prize money)$1.4M
- Jul 2022Grant (prize money)$259.6K
#12
Public · San Diego, California · founded 2002 · 364 employees$124.2Mraised▾
Provider of genome analysis solutions to researchers and clinicians. It offers Saphyr system that uses a non-sequencing based optical mapping technology to analyse extremely long strands of genomic DNA. It is used for detecting genomic variants missed by next-generation sequencing (NGS) technologies and conventional cytogenetic techniques.
- May 2024Post IPO$20M
- Mar 2019Post IPO$2.5M
- Dec 2014Series C$68.4M
- Jun 2014Series B$5M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Genomics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Bioinformatics is moving in the United States
A read on the academic research around Bioinformatics — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 13,110 United States-affiliated papers.
- Harvard University633
- Broad Institute433
- Howard Hughes Medical Institute318
- Stanford University287
- Johns Hopkins University287
- Gene83→532
- Transcriptome25→436
- Genome117→419
- Disease6→218
- Immune system11→219
- Disease17→407
- Immune system4→266
- Gene38→281
- Transcriptome13→238
- Biomarker2→208
- Disease27→311
- Immune system6→152
- Cancer17→130
- Clinical trial4→111
- Biomarker2→92
Where bioinformatics is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing bioinformatics patents in the United States
United States bioinformatics patent filing is accelerating — 246 filings from 64 assignees (2016–2025), led by Edico Genome, Illumina, UNIV Washington; annual filings 22→23.
- Edico Genome129
- Illumina60
- UNIV Washington18
- Nantomics9
- Baluch Mohamed Khoso7
- Genomsys7
- Microsoft6
- Contamination Source Identificat5