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Radar · Cardiac and Vascular Disorders in United States

Best Cardiac and Vascular Disorders Companies in United States

The 1315 best Cardiac and Vascular Disorders companies in United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Everest Medicines.

1315companies tracked
$26.5Bdisclosed funding
0unicorns
693have raised

Ranked by disclosed equity funding and funding momentum, this directory captures 1,315 Cardiac and Vascular Disorders companies across the United States, representing $26.5 billion in total disclosed capital. The scale here is real. Nineteen validated filers report a combined revenue pool of roughly $2.7 billion, with a median revenue of $9 million growing at 9% year-over-year. But the outsized earners pull that pool hard: Edwards Lifesciences Corp booked $1.6 billion in revenue at 17% growth, and its $381 million net income sits at 44 times the sector median. Shockwave Medical posted $219 million at a sharp 36% clip, clearing $55 million in net income, or 6 times that same median. Kiniksa Pharmaceuticals delivered 56% revenue growth to $214 million. These aren't projections, they're filed figures.

On the funding side, Imperative Care leads at $496 million raised, with Impulse Dynamics close behind at $443 million and Corxel at $287 million. So if you're mapping capital concentration, those three names are your anchors. Government-backed investors including HHS, NIH, and the National Science Foundation dominate the active investor list, which tells you something about where early-stage bets are coming from. As shown in 2011 research, cardiovascular intervention outcomes carry long-term systemic cost implications, which partly explains why public capital keeps flowing into this space. I'd watch the cardiovascular hospital and prostate cancer adjacencies, both flagged as rising themes across current coverage.

Ranked: Best Cardiac and Vascular Disorders companies in United States

#CompanyDisclosed fundingLast roundStageEmployeesFounderMarket signals (1y)Patents & IP focusRecent signals
1Imperative Care
Provider of access catheters for cardiovascular diagnosis and treatment
82Funding top 14%Patents top 15%Innovation top 18%Moat top 26%
All 10 signals ▾
Fundingtop 14%
Patentstop 15%
Innovationtop 18%
Moattop 26%
Growthtop 27%
Techtop 36%
Talenttop 38%
Markettop 48%
Newsbottom 48%
Globalbottom 42%
Funding: Raised $496M across 4 rounds · 4 rounds over 7 yrs (0.6/yr)
Patents: 261 patents matched (strict assignee match) · 225 filings since 2022 vs 36 in 2017-21
rank vs industry peers · Fliar Intelligence Index 82/100
$496M3 mo agoSeries E90Dr Hopkins
Co-founder
4 signals ▼33%
Funding
261 patents
Robotic-assisted neurovascular catheter systems for precise multi‑catheter interventions
—
2Impulse Dynamics
Provider of implantable device for treatment of chronic heart failure
40Funding top 13%Moat top 31%Product top 34%Tech top 49%
All 10 signals ▾
Fundingtop 13%
Moattop 31%
Producttop 34%
Techtop 49%
Patentsbottom 49%
Globalbottom 46%
Innovationbottom 45%
Marketbottom 41%
Growthbottom 38%
Newsbottom 27%
Funding: Raised $443M across 8 rounds · 8 rounds over 10 yrs (0.8/yr)
Moat: Editorial + unicorn rating 8/10 · IP moat: 18 patents
rank vs industry peers · Fliar Intelligence Index 40/100
$443M6 mo agoSeries F36——18 patents
Implantable cardiac muscle stimulation devices and protein‑based therapeutic modulation.
—
3CORXEL
Developer of therapies for patients with cardiometabolic conditions
$287M4 mo agoSeries D—Sandy Mou
CEO
———
4Ablative Solutions
Developer of renal denervation for treatment of hypertension
$260M7 mo agoSeries D24——173 patents
Patents concentrated in health & consumer products
—
5Tenaya Therapeutics
Developer of regenerative and gene therapeutics for heart failure
$248M16 mo agoPublic141
141 → 93 (-34%) · sector median +22%
Benoit Bruneau
Co-Founder
—207 patents
Engineered AAV capsids and CRISPR guides for cardiac gene‑therapy targeting PLN mutations
—
6Rivus Pharmaceuticals
Developer of therapeutics for cardio-metabolic disorders
$233M17 mo agoSeries B12Allen Cunningham
CEO
——1 launch
7Cardiac Dimensions
Developer of invasive cardiac implants for heart failure
$208M14 mo agoSeries E31
31 → 73 (+135%) · sector median +22%
——154 patents
Recapturable cardiac valve repair devices and modular implant delivery systems
—
8Orchestra BioMed
Developer of medical devices for hypertension and atherosclerosis treatment
$206M10 mo agoPublic47Darren Sherman
President
12 signals ▲300%
Announcements · Capital raise · Earnings
—1 partnership
9Braveheart
Developer of a treatment for hypertrophic cardiomyopathy and related conditions
$185M7 mo agoSeries A—Travis Murdoch
CEO & President
———
10Bioventrix
Ventricle reshaping device
40Funding top 16%Moat top 19%Patents top 36%Talent top 38%
All 9 signals ▾
Fundingtop 16%
Moattop 19%
Patentstop 36%
Talenttop 38%
Innovationtop 43%
Globalbottom 45%
Techbottom 36%
Marketbottom 30%
Newsbottom 27%
Funding: Raised $181M across 25 rounds · 25 rounds over 22 yrs (1.1/yr)
Moat: Editorial + unicorn rating 8/10 · IP moat: 185 patents
rank vs industry peers · Fliar Intelligence Index 40/100
$181M2 mo agoSeries E20
20 → 23 (+15%) · sector median +22%
Lon Annest
Co-Founder
—185 patents
Percutaneous cardiac implant and monitoring systems for heart failure treatment
—
11Eko
Provider of AI-based remote patient monitoring platform for cardiac health
72Funding top 16%Customers top 22%Tech top 25%Product top 30%
All 11 signals ▾
Fundingtop 16%
Customerstop 22%
Techtop 25%
Producttop 30%
Moattop 31%
Talenttop 43%
AItop 45%
Markettop 48%
Globalbottom 45%
Growthbottom 44%
Newsbottom 20%
Funding: Raised $167M across 16 rounds · 16 rounds over 11 yrs (1.5/yr)
Customers: Play-Store rating 4.81★ across 4,901 ratings (2 apps) · Review volume +17% in 6 mo
rank vs industry peers · Fliar Intelligence Index 72/100
$167M14 mo agoSeries D95
95 → 204 (+115%) · sector median +22%
Jason Bellet
Co-Founder
——1 launch
12Vital Connect
Developer of biosensor patch for body vitals monitoring
64Product top 18%Funding top 21%Moat top 26%Patents top 32%
All 11 signals ▾
Producttop 18%
Fundingtop 21%
Moattop 26%
Patentstop 32%
Talenttop 34%
Innovationtop 36%
Growthtop 43%
Techtop 45%
Markettop 49%
Globalbottom 47%
Newsbottom 18%
Product: 6 distinct product lines · Company stage: Series G
Funding: Raised $140M across 8 rounds · 8 rounds over 15 yrs (0.5/yr)
rank vs industry peers · Fliar Intelligence Index 64/100
$140M15 mo agoSeries G184
184 → 199 (+8%) · sector median +22%
Nersi Nazari
Founder
—239 patents
Wearable biosensor systems for continuous cardiovascular and vital‑sign monitoring
—
13Anteristech
Provider of technologies for developing heart valve
$126M7 mo agoPublic27—14 signals ▲100%
Funding · Capital raise · IPO
——
14Supira Medical
Developer of ventricular assist devices for coronary intervention and cardiogenic shock
$120M14 mo agoSeries E78———3 launchs
15EnChannel Medical
Developer of medical device for cardiac disorders
$110M13 mo agoSeries B—Graydon Beatty
Co-Founder
———
16Galvanize
Developer of pulsed electric field systems for various medical indications
$110M11 mo agoSeries C114Jonathan Waldstreicher
Founder & CEO
8 signals
Funding · Leadership · New product
——
17Neochord
Provider of minimally -invasive devise for valve repair
$108M15 mo agoSeries E7David Chung
President & CEO
—142 patents
Minimally invasive cardiac valve repair devices and suture anchoring technologies
—
18Corvia Medical
Developer of transcatheterally shunt for treating diastolic heart failure disease
$105M12 mo agoAcquired32
32 → 38 (+19%) · sector median +22%
George Fazio
President & CEO
———
19Alleviant Medical
Developer of devices to lift the burden of heart failure
$89M15 mo agoSeries C37Jacob Kriegel Md
Co-Founder & CMO
———
20Field Medical
Developer of device for the treatment of heart arrhythmia conditions
$89M11 mo agoSeries B352Steven Mickelsen
Founder & CTO
——1 expansion
214C Medical
Developer of medical devices for the treatment of mitral regurgitation
$88M15 mo agoSeries D28Jeffrey Chambers
Founder
—547 patents
Minimally invasive electrosurgical instruments and RF‑activated surgical systems for laparoscopy
—
22Reprieve Cardiovascular
Developer of decongestion management solution for acute decompensated heart failure patients
$84M10 mo agoSeries B16——61 patents
Non‑invasive urine output monitoring and personalized fluid therapy for heart failure patients
—
23BioIntelliSense
Developer of medical-grade wearable devices and data services for patient monitoring
50Funding top 21%Moat top 21%Patents top 25%Innovation top 26%
All 10 signals ▾
Fundingtop 21%
Moattop 21%
Patentstop 25%
Innovationtop 26%
Producttop 35%
Talenttop 38%
Techbottom 49%
Globalbottom 40%
Marketbottom 36%
Customersbottom 3%
Funding: Raised $82.0M across 4 rounds · 4 rounds over 8 yrs (0.5/yr)
Moat: Editorial + unicorn rating 8/10 · IP moat: 47 patents
rank vs industry peers · Fliar Intelligence Index 50/100
$82M6 mo agoSeries C26James Mault
Co-Founder&CEO
—47 patents
Wearable multi-parameter physiological monitoring and biosensing devices
—
24Corsera Health
Developer of technology predicting and preventing cardiovascular disease before it begins
72Funding top 24%Talent top 28%AI top 45%Global bottom 48%
All 4 signals ▾
Fundingtop 24%
Talenttop 28%
AItop 45%
Globalbottom 48%
Funding: Raised $80.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr)
Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
rank vs industry peers · Fliar Intelligence Index 72/100
$80M5 mo agoSeries A—Chris Cox
Co-Founder
———
25Tioga Cardiovascular
Developer of valve replacement solutions
$75M9 mo agoSeries C53Amr Salahieh
Co-Founder
———
26Adagio Medical
Stealth mode startup developing cardiovascular therapies
$72M8 mo agoPublic72
72 → 52 (-28%) · sector median +22%
Olav Bergheim
Founder
3 signals ▼75%
Funding
158 patents
Catheter-based cryoablation systems with conductive liners and shape‑memory steering.
5 job openings
27Polares Medical
Developer of medical devices for treating mitral valve regurgitation
$65M3 mo agoSeries C20Jacques Essinger
Founder & CEO
3 signals
Funding · Capital raise
——
28Instylla
Developer of hydrogel technology for embolization therapy
$64M11 mo agoSeries B26———2 launchs
29AtaCor Medical
Transforming cardiac rhythm management with innovative extravascular pacing and defibrillation solutions
$62M8 mo agoSeries D15
15 → 33 (+120%) · sector median +22%
Alan Marcovecchio
Co-Founder & VP Clinical
—146 patents
Implantable cardiac pacing lead delivery, sensing, and control technologies
—
30Ionetix
Radiopharmaceutical solutions provider specializing in cyclotron technology and targeted alpha therapy
$61M3 mo agoSeries C50Kevin Cameron
CEO
—9 patents
Compact superconducting cyclotron systems for medical and research particle acceleration
3 job openings
31Mezzion
Developer of medicine for single ventricle heart disease
$60M12 mo agoPublic10Dean Park
Founder & CEO
———
32Shape Memory Medical
Developer of embolization devices based on Shape Memory Polymer material
$57M14 mo agoSeries C37
37 → 46 (+24%) · sector median +22%
Edward Ruppel
CEO & President
———
33Aronora
Developing first-in-class biologics for life-threatening blood diseases with unmet needs
$55M9 mo agoSeed8Erik Tucker
President & CEO
—45 patents
Antibody-based anticoagulant therapeutics targeting coagulation factors XI, XII, thrombin, and thrombopoietin.
—
34Okami Medical
Developer of innovative, versatile, and intuitive medical devices for peripheral vessels treatment
$55M6 mo agoSeries F8Paul Lubock
Co-Founder
5 signals ▲400%
Funding
—2 launchs
35Cagent Vascular
Developer of a device for removal of vascular blockages
57Moat top 21%Funding top 24%Patents top 30%Innovation top 31%
All 9 signals ▾
Moattop 21%
Fundingtop 24%
Patentstop 30%
Innovationtop 31%
Techtop 34%
Talentbottom 49%
Globalbottom 45%
Marketbottom 39%
Newsbottom 21%
Moat: Editorial + unicorn rating 7/10 · IP moat: 117 patents
Funding: Raised $54.4M across 7 rounds · 7 rounds over 12 yrs (0.6/yr)
rank vs industry peers · Fliar Intelligence Index 57/100
$54M1 mo agoSeries D40Robert Giasolli
Founder
—117 patents
Drug‑eluting serrated balloon catheters for precise intravascular drug delivery
1 launch
36Peerbridge Health
Developer of ambulatory ECG system with AI-enabled cardiac diagnostics
42Innovation top 23%Funding top 27%Product top 30%Moat top 39%
All 7 signals ▾
Innovationtop 23%
Fundingtop 27%
Producttop 30%
Moattop 39%
Techtop 48%
Globalbottom 37%
Marketbottom 19%
Innovation: 4 product lines · Deep-tech classification: Tech Hardware
Funding: Raised $46.1M across 14 rounds · 14 rounds over 11 yrs (1.3/yr)
rank vs industry peers · Fliar Intelligence Index 42/100
$46M13 mo agoSeries B3———1 launch · 1 expansion
37Aria CV
Device for pulmonary hypertension
$44M10 mo agoSeries B17Dan Gladney
Chief Executive Officer
—59 patents
Implantable cardiovascular pressure-regulating devices for pulmonary hypertension treatment
—
38InspireMD
Stents integrated with a bio-stable mesh
$34M10 mo agoPublic66
66 → 121 (+83%) · sector median +22%
—3 signals ▼70%
Earnings · Contracts
——
39LifeLens
Developer of wireless ECG monitor for personal health monitoring use
37Talent top 28%Funding top 32%Product top 35%Moat top 38%
All 9 signals ▾
Talenttop 28%
Fundingtop 32%
Producttop 35%
Moattop 38%
Techbottom 48%
Innovationbottom 47%
Marketbottom 34%
Patentsbottom 32%
Globalbottom 31%
Talent: 4 named leaders on record · 4 C-suite/founder profiles curated
Funding: Raised $24.6M across 5 rounds · 5 rounds over 7 yrs (0.7/yr)
rank vs industry peers · Fliar Intelligence Index 37/100
$25M7 mo agoSeries B45David Robins
Co-Founder
—5 patents
Patents concentrated in health & consumer products
—
40Secretome Therapeutics
Developer of cell-based therapies for multiple diseases
$22M0 mo agoSeries A8Sudhish Sharma
Co-Founder
———
41Jupiter Endovascular
Developer of minimally invasive medical devices for endovascular intervention
$21M8 mo agoSeries B—Carl St Bernard
Chief Executive Officer
———
42SOLEY Therapeutics
Developer of stem cell secreted factors for the treatment of myocardial infarction and stroke
$20M5 mo agoSeries C10Yerem Yeghiazarians
Co-Founder & CEO
——1 job opening · 1 launch
43Centese
Developer of a surgical drainage system
$18M0 mo agoSeries B13Evan Luxon
Co-Founder & CEO
—25 patents
Negative-pressure chest and wound drainage systems for thoracic surgery
2 launchs
44Thrombolex
Developer of endovascular catheters for acute venous thromboembolic conditions
$18M3 mo agoSeries A18——41 patents
Interventional catheter baskets for embolic removal and infusion drug delivery
3 launchs
45Venturemed Group
Developer of endovascular devices for the treatment of PAD and stenoses of AV fistulas and grafts
$16M8 mo agoSeries C15Denis Harrington
President & CEO
3 signals
Leadership · Funding
36 patents
Advanced intravascular catheters with expandable, incising, drug‑delivery and embolic protection features
—
46VisCardia
Developer of implantable medical therapy for the treatment of heart failure
$16M8 mo agoSeries C5——70 patents
Implantable diaphragmatic stimulation systems for cardiac and respiratory therapeutic support
—
47Micro Medical Solutions
Developer of a device for CLI and PAD patients to prevent amputation
$13M7 mo agoSeries B13Gregory Sullivan
Co-Founder & CEO
———
48Piraeus Medical
Developer of solutions for stroke thrombectomy procedures
$11M2 mo agoSeries B—Jared Hutar
Chief Executive Officer
———
49Sonovascular
eveloper of a medical device to treat arterial and venous diseases
$8M4 mo agoSeries A8Daniel Estay
Founder & CEO
—7 patents
Intravascular ultrasound catheter technology for enhanced imaging and therapeutic delivery.
—
50Cloud
Provider of cloud-based remote cardiology vital signs monitoring devices and platforms
67Growth top 21%Innovation top 22%Patents top 23%Moat top 32%
All 11 signals ▾
Growthtop 21%
Innovationtop 22%
Patentstop 23%
Moattop 32%
Fundingtop 35%
Fin. healthtop 38%
Producttop 39%
Techbottom 48%
Globalbottom 46%
Newsbottom 40%
Marketbottom 37%
Growth: Revenue +701% YoY · Fresh capital in last 24 mo
Innovation: 85 patents (top 21% of patent-holders) · 23 filings since 2022 vs 14 in 2017-21
rank vs industry peers · Fliar Intelligence Index 67/100
$3M2 mo agoPublic55——85 patents
Remote health monitoring, biomedical AR, and networked fax/telemedicine data transmission
—

Top 12 Cardiac and Vascular Disorders companies in United States

#1
Series E · Campbell, California · founded 2015 · 90 employees
$496Mraised
▾

Provider of access catheters for cardiovascular diagnosis and treatment. The catheters are used in deep navigation into the blood vessels of the brain to prevent strokes. The flagship product ZOOM Aspiration System is a family of products designed to facilitate clot removal during ischemic stroke.

Fliar Intelligence Index™ 82how this company ranks against its industry peers
Funding
top 14%
Patents
top 15%
Innovation
top 18%
Moat
top 26%
Growth
top 27%
Tech
top 36%
Funding: Raised $496M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) · Last round Series E (Mar 2026)
Patents: 261 patents matched (strict assignee match) · 225 filings since 2022 vs 36 in 2017-21 · Latest publication 2026
Innovation: 261 patents (top 10% of patent-holders) · 225 filings since 2022 vs 36 in 2017-21
Audience (LinkedIn): 37k LinkedIn followers — 14.3% of this cohort's audience
Funding rounds
  • Mar 2026Series E$100M
  • Jul 2024Series E$150M
  • Jul 2021Series D$260M
  • Dec 2019Series C$86M
Founders & team
Dr HopkinsCo-founderFred KhosraviCo-Founder & CEO
Investors
Delos Capital, HealthCor Partners, Ally Bridge Group, Rock Springs Capital, Ascension, Innovatus Capital Partners
Tech stack
Apple Icloud MailAutoptimizeCdnjsCloudflareCloudflare Bot ManagementContact Form 7
#2
Series E · San Ramon, California · founded 2003 · 20 employees
$181.4Mraised
▾

BioVentrix develops clinical solutions for treating heart failure patients. It provides PliCath HF, an epicardial catheter-based ventricular reconstruction device. Product is not commercially available.

Fliar Intelligence Index™ 40how this company ranks against its industry peers
Funding
top 16%
Moat
top 19%
Patents
top 36%
Talent
top 38%
Innovation
top 43%
Global
bottom 45%
Funding: Raised $181M across 25 rounds · 25 rounds over 22 yrs (1.1/yr) · Last round Series E (Apr 2026)
Moat: Editorial + unicorn rating 8/10 · IP moat: 185 patents · Soonicorn
Patents: 185 patents matched (strict assignee match) · 29 filings since 2022 vs 71 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 5k LinkedIn followers
Activity (LinkedIn): 1 partnerships (incl. BioVentrix, Inc.) announced in 12 mo
Funding rounds
  • Apr 2026Series E$705K
  • Oct 2024Series E$6.7M
  • Mar 2024Series E$3.6M
  • Apr 2023Series E$48.5M
Founders & team
Lon AnnestCo-FounderDavid RCo-CEO
Investors
Taglich Brothers, Andera Partners, Cormorant Asset Management, Squarepoint Capital, Richmond Brothers, Telegraph Hill Partners
Tech stack
BootstrapCloudwaysGoogle AnalyticsGsapIsotopeJquery
#3
Series F · Marlton, New Jersey · founded 1998 · 36 employees
$443.1Mraised
▾

Impulse Dynamics is focussed on developing solutions for the treatment of Chronic Heart Failure. They have developed, Optimizer IV, a minimally invasive implantable device based on novel Cardiac Contractility Modulation (CCM) technology, and delivers non-excitatory electric pulses. The Optimizer is CE is FDA approved.

Fliar Intelligence Index™ 40how this company ranks against its industry peers
Funding
top 13%
Moat
top 31%
Product
top 34%
Tech
top 49%
Patents
bottom 49%
Global
bottom 46%
Funding: Raised $443M across 8 rounds · 8 rounds over 10 yrs (0.8/yr) · Last round Series F (Dec 2025)
Moat: Editorial + unicorn rating 8/10 · IP moat: 18 patents · Soonicorn
Product: 1 distinct product line · Company stage: Series F
Audience (LinkedIn): 14k LinkedIn followers — 5.6% of this cohort's audience
Funding rounds
  • Dec 2025Series F$158M
  • Feb 2025Unattributed$84.1M
  • Feb 2024Series E$136.5M
  • Jul 2023Series E$91.4M
Investors
Redmile Group, Perceptive Advisors, Alger, Hobart Healthcare, Goldstone Investment, Abiomed
Tech stack
Animate.CssAzureChart.JsDiviFlywheelFont Awesome
#4
Series D · Wayne, Pennsylvania · founded 2014 · 40 employees
$54.4Mraised
▾

Developer of a device for removal of vascular blockages. The company is developing a Lesion Preparation balloon designed to enable more effective removal of blockages in blood vessels and to increase drug uptake when used along with a Drug-Coated Balloon. Their technology has applications in the treatment of Peripheral arterial disease.

Fliar Intelligence Index™ 57how this company ranks against its industry peers
Moat
top 21%
Funding
top 24%
Patents
top 30%
Innovation
top 31%
Tech
top 34%
Talent
bottom 49%
Moat: Editorial + unicorn rating 7/10 · IP moat: 117 patents
Funding: Raised $54.4M across 7 rounds · 7 rounds over 12 yrs (0.6/yr) · Last round Series D (May 2026)
Patents: 117 patents matched (strict assignee match) · 54 filings since 2022 vs 54 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 7k LinkedIn followers — 2.7% of this cohort's audience
Activity (LinkedIn): 1 product launches announced in 12 mo
Funding rounds
  • May 2026Series D$41M
  • Feb 2025Series C$15M
  • Jan 2024Series C$30M
  • Jun 2021Series B$9.5M
Founders & team
Robert GiasolliFounder
Investors
Sectoral, USVP, Synergy Ventures, Ben Franklin Technology Partners, Trinity Capital, M&L Healthcare
Tech stack
CloudflareCloudflare Bot ManagementCloudflare Browser InsightsCookiebotCore-JsDigitalocean Spaces
#5
Series D · Berkeley Heights, New Jersey · founded 2019
$287Mraised
▾

Developer of therapies for patients with cardiometabolic conditions. It offers a pipeline of treatments including an oral small molecule GLP-1 receptor agonist for the treatment of obesity and diabetes mellitus, JX10 is an investigational drug for acute ischemic stroke, and JX09 a next-generation highly selective aldosterone synthase inhibitor for hypertension, heart failure and chronic kidney disease.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 4k LinkedIn followers
Funding rounds
  • Jan 2026Series D$287M
Founders & team
Sandy MouCEO
Investors
SR One, TCG Crossover, RA Capital Management, HBM Healthcare Investments, SymBiosis, Adage Capital Management
Tech stack
CloudflareCloudflare Browser InsightsCloudflare Rocket LoaderGoogle Font ApiHstsHttp/3
#6
Series D · Kalamazoo, Michigan · founded 2011 · 24 employees
$259.6Mraised
▾

Developer of renal denervation for treatment of hypertension. The company has developed a catheter-based approach for the delivery of diagnostic and therapeutic agents into the area surrounding the peripheral blood vessels. The Peregrine renal denervation system is being evaluated for treating hypertension.

Funding rounds
  • Nov 2025Series D$10.4M
  • Dec 2024Series D$37.2M
  • Mar 2023Series D$29.3M
  • Jun 2022Series D$91.4M
Investors
Charter Capital Partners, BioStar Capital, Gilde Healthcare, Novus Life Sciences, Invus, Novus Biotechnology Fund
Tech stack
NginxCloudways
#7
Series C · Palo Alto, California · founded 2010 · 20 employees
$65Mraised
▾

Developer of medical devices for treating mitral valve regurgitation. The company is developing a minimally-invasive trans-catheter hemi-replacement system, PLAR system, to treat insufficiency in the function of the mitral valve.

Funding rounds
  • Mar 2026Series C$50M
  • Jun 2020Series B$40M
  • Jul 2018Series A$25M
Founders & team
Jacques EssingerFounder & CEOJacques EssingerCEO
Investors
Decheng Capital, Endeavour Vision, IDO Investments, Earlybird, Wellington Partners Venture Capital, Longitude Capital
#8
Series A · Dallas, Texas · founded 2018 · 8 employees
$22.1Mraised
▾

Developer of cell-based therapies for multiple diseases. It offers a lead product STM-21 to prevent the inflammatory toxicities of cancer treatment which include cisplatin-induced acute kidney injury. It also offers STM-01 a cellular therapy comprised of the neonatal MSCs for restoring cardiac function in a heart attack.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 3k LinkedIn followers
Funding rounds
  • Mar 2026Series B$250K
  • Nov 2024Series B$20.4M
  • Oct 2019Seed$1.5M
Founders & team
Sudhish SharmaCo-FounderMuthukumar GunasekaranCo-FounderRachana MishraCo-Founder
Investors
Maryland Momentum Fund, Parent Project Muscular Dystrophy, RA Capital Management, USM
Tech stack
CloudflareCloudflare Bot ManagementDiviGodaddyGodaddy CoblocksGoogle Analytics
#9
Series C · San Francisco, California · founded 2009 · 50 employees
$61.1Mraised
▾

Radiopharmaceutical solutions provider specializing in cyclotron technology and targeted alpha therapy. The company provides full-service radioisotope production and end-to-end radiopharmaceutical manufacturing solutions. It developed a compact superconducting cyclotron used to produce N-13 Ammonia, a PET imaging agent. The company establishes a network of cyclotrons installed near PET programs, making this tracer accessible and affordable. It supports the development and commercialization of targeted alpha therapy (TAT), an emerging cancer therapy utilizing alpha radionuclides. The company is committed to the design, manufacturing, and support of safe and effective radiopharmaceutical products. It offers a turnkey solution eliminating the expense of launching a Cardiac PET program. The company fosters scientific partnerships and sponsorships to deliver advanced radiopharmaceuticals, providing access to scarce diagnostics and therapeutic radiopharmaceuticals.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 4k LinkedIn followers
Hiring: 3 hiring posts in 12 mo (public) · momentum +3 · hiring: Production Chemist, Senior Human Resources Business Partner
Funding rounds
  • Feb 2026Post IPO$30M
  • Aug 2024Series C—
  • May 2020Series C$37.3M
  • Mar 2018Series B$23.8M
Founders & team
Kevin CameronCEO
Investors
Lilly, Tees River, Riverland Capital
Tech stack
WordpressMysqlPhpThree.JsYoast SeoApache Http Server
#10
Series A · San Francisco, California · founded 2025
$185Mraised
▾

Developer of a treatment for hypertrophic cardiomyopathy and related conditions. It focuses on addressing the underlying mechanisms of the condition to improve heart performance. The company is advancing its investigational treatment through late-stage clinical development. Hypertrophic cardiomyopathy causes the heart muscle to become abnormally thick, particularly in the left ventricle.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 3k LinkedIn followers
Activity: 1 product launches announced in 12 mo
Funding rounds
  • Nov 2025Series A$185M
Founders & team
Travis MurdochCEO & President
Investors
Andreessen Horowitz, Forbion, Orbimed, Enavate Sciences, Frazier Life Sciences
#11
Public · Eagan, Minnesota · founded 2006 · 27 employees
$126.2Mraised
▾

Provider of technologies for developing heart valve. The company has developed a 3D single-piece aortic valve called the DurAVR heart valve that uses its patented ADAPT technology. The other products developed are DurAVR leaflet repair (RP), DurAVR transcatheter heart valve (THV), DurAVR surgical heart valve (SHV).

LinkedIn Pulse recent public activity · Jul 2026
Audience: 12k LinkedIn followers — 4.6% of this cohort's audience · 98 engagements/post (2.0× cohort median)
Funding rounds
  • Oct 2025Post IPO$11.5M
  • Apr 2024Post IPO$15.2M
  • Mar 2022Post IPO$20M
  • Oct 2021Post IPO$3.8M
Investors
Mercer, Perceptive Advisors, Star Bright Holding, HHS, Lifeblood Capital
Tech stack
Adobe AnalyticsAdobe Client Data LayerAdobe Experience ManagerAdobe Experience Platform LaunchApple Icloud MailBamboohr
#12
Series B · Omaha, Nebraska · founded 2016 · 13 employees
$17.9Mraised
▾

Developer of a surgical drainage system. The Thoraguard is integrated with a software to notify the clinical staff for any leakages through an alarm. The system is integrated with sensors and software offers automated management for suction and tracks the drainage output rates. The system also has clog-free chest tubes.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 1k LinkedIn followers
Activity: 2 product launches announced in 12 mo
Funding rounds
  • May 2025Series B$525K
  • May 2025Conventional Debt—
  • Nov 2023Series B$15M
  • Nov 2017Seed$2.9M
Founders & team
Evan LuxonCo-Founder & CEO
Investors
Invest Nebraska, Medical Technology Venture Partners, iiM, Scientific Health Development, UCSF Rosenman Institute
Tech stack
WordpressMysqlPhpGoogle MapsTwenty TwentyVimeo

Funding & investor landscape

$26.5Btotal disclosed funding
732companies funded
2,757disclosed rounds
5rounds last 90 days
Most active investors
HHS149 rounds
NIH27 rounds
National Science Foundation26 rounds
Broadview Ventures21 rounds
Saints Capital20 rounds
BioStar Capital19 rounds
New Enterprise Associates17 rounds
Boston Scientific16 rounds
New Leaf Venture Partners16 rounds
SV Health Investors16 rounds

Notable founders

Dr Hopkins
Co-founder · Imperative Care
Fred Khosravi
Co-Founder & CEO · Imperative Care
Lon Annest
Co-Founder · Bioventrix
David R
Co-CEO · Bioventrix
Robert Giasolli
Founder · Cagent Vascular
Sandy Mou
CEO · CORXEL
Jacques Essinger
Founder & CEO · Polares Medical
Sudhish Sharma
Co-Founder · Secretome Therapeutics
Muthukumar Gunasekaran
Co-Founder · Secretome Therapeutics
Kevin Cameron
CEO · Ionetix
Travis Murdoch
CEO & President · Braveheart
Evan Luxon
Co-Founder & CEO · Centese
Prism market signals · United States · country-scoped Prism corpus, 18,792,859 docs

Market landscape — 10 sub-themes by coverage

Share of Cardiac and Vascular Disorders coverage by sub-theme.

Regulatory-risk over time rising

Funding & growth over time

funding rising · growth rising

Common questions

How many Cardiac and Vascular Disorders companies are there in United States?
Radar tracks 1315 indexable Cardiac and Vascular Disorders companies headquartered in United States that meet our profile-completeness bar.
What is the total funding raised by Cardiac and Vascular Disorders companies in United States?
The Cardiac and Vascular Disorders companies in United States on this list have raised a combined $26.5B in disclosed equity funding across 732 funded companies.
Which is the highest-funded Cardiac and Vascular Disorders company in United States?
Everest Medicines is the highest-funded Cardiac and Vascular Disorders company in United States, with $593M in disclosed equity funding.
How many Cardiac and Vascular Disorders companies in United States are funded?
732 of the 1315 Cardiac and Vascular Disorders companies in United States on this list have disclosed at least one equity funding round.
How many Cardiac and Vascular Disorders unicorns are there in United States?
None of the Cardiac and Vascular Disorders companies in United States on this list currently has a disclosed valuation of $1B or more.
Who are the top investors in United States Cardiac and Vascular Disorders companies?
The most active investors in United States Cardiac and Vascular Disorders companies on this list include HHS, NIH, National Science Foundation, Broadview Ventures, Saints Capital.
Riya SenguptaFinancials

Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.

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