Best Disease Self Management Companies in California, United States
The 936 best Disease Self Management companies in California, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Jawbone.
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in California
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | App-install YoY | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jawbone 🦄 Provider of wearable devices for activity and sleep tracking | $877M | 125 mo ago | 50 | — | Squarespace CommerceSquarespaceTypeScript+13 | — | — | — |
| 2 | Cue Health Provider of health monitoring system for diagnosing diseases like influenza | $406M | 61 mo ago | 726 | — | — | — | 123 patents Rapid point‑of‑care molecular diagnostics and sample collection devices for analyte detection | — |
| 3 | Virta 🦄 Provider of therapies for metabolic health in chronic disease patients | $402M | 61 mo ago | 443 443 → 902 (+104%) · sector median +84% | Jeff Volek Co-Founder & Chief Science Officer | WebflowSalesforceVideoJS+29 | +60% | 3 patents Cable‑suspended ground transport and overland conveyor systems for material handling | — |
| 4 | Willow Wearable double electric breast pump kits | $228M | 29 mo ago | 109 | John Chang Co-Founder & Chief Technical Officer | Amazon WebstoreCart FunctionalityShopify+34 | — | 16 patents Patents concentrated in electrical & electronics | — |
| 5 | Eargo Provider of hearing aids for people with hearing disabilities | $217M | 47 mo ago | 45 | Florent Michel Co-Founder | Apple iCloud MailGoogle WorkspaceNode.js+28 | — | 92 patents Wireless-enabled hearing aid devices, charging, tip customization, and diagnostic testing solutions | 1 award |
| 6 | Glooko Glucose meter and mobile app for diabetes management 53Funding top 18%Product top 27%Tech top 29%Moat top 35% All 12 signals ▾Fundingtop 18% Producttop 27% Techtop 29% Moattop 35% Growthtop 43% Markettop 46% Talentbottom 49% Globalbottom 47% Customersbottom 40% Patentsbottom 34% Innovationbottom 30% Newsbottom 20% Funding: Raised $201M across 8 rounds · 8 rounds over 15 yrs (0.5/yr) Product: 2 published apps (452k installs) · Company stage: Series F rank vs industry peers · Fliar Intelligence Index 53/100 | $201M | 20 mo ago | 121 121 → 237 (+96%) · sector median +84% | Mike Alvarez CEO | WordPress Block EditorWordPressApple iCloud Mail+38 | +29% | 5 patents Digital diabetes management: glucose data analytics and personalized activity recommendation systems. | 2 launchs |
| 7 | Headspace 🦄 Provider of mental health support services via application and human care 76Customers top 21%Tech top 22%Funding top 25%Moat top 26% All 11 signals ▾Customerstop 21% Techtop 22% Fundingtop 25% Moattop 26% Talenttop 28% Markettop 31% Producttop 35% AItop 45% Globalbottom 46% Growthbottom 29% Newsbottom 24% Customers: Play-Store rating 4.27★ across 339,862 ratings (2 apps) · Review volume +3% in 6 mo Tech: 58 technologies across 7/8 capability areas · Cloud: Amazon Alb, Amazon Cloudfront rank vs industry peers · Fliar Intelligence Index 76/100 | $178M | 34 mo ago | 906 906 → 1,557 (+72%) · sector median +84% | Andy Puddicombe Co-Founder | Cart FunctionalityContentfulTurbopack+23 | +9% | — | — |
| 8 | Biolinq Provider of a wearable biosensor platform for diabetes monitoring 67Innovation top 13%Funding top 17%Patents top 17%Moat top 26% All 10 signals ▾Innovationtop 13% Fundingtop 17% Patentstop 17% Moattop 26% Talenttop 38% Growthtop 45% Marketbottom 45% Globalbottom 43% Techbottom 39% Newsbottom 18% Innovation: 189 patents (top 11% of patent-holders) · 161 filings since 2022 vs 28 in 2017-21 Funding: Raised $175M across 15 rounds · 15 rounds over 12 yrs (1.2/yr) rank vs industry peers · Fliar Intelligence Index 67/100 | $175M | 15 mo ago | 91 | Jared Tangney Co-Founder | Webflowcore-jsjQuery+11 | — | 189 patents Minimally invasive microneedle-based continuous biosensing for interstitial fluid analytes | — |
| 9 | Eko Provider of AI-based remote patient monitoring platform for cardiac health 72Funding top 16%Customers top 22%Tech top 25%Product top 30% All 11 signals ▾Fundingtop 16% Customerstop 22% Techtop 25% Producttop 30% Moattop 31% Talenttop 43% AItop 45% Markettop 48% Globalbottom 45% Growthbottom 44% Newsbottom 20% Funding: Raised $167M across 16 rounds · 16 rounds over 11 yrs (1.5/yr) Customers: Play-Store rating 4.81★ across 4,901 ratings (2 apps) · Review volume +17% in 6 mo rank vs industry peers · Fliar Intelligence Index 72/100 | $167M | 14 mo ago | 95 95 → 204 (+115%) · sector median +84% | Jason Bellet Co-Founder | Cart FunctionalityShopifyApple iCloud Mail+40 | +43% | — | 1 launch |
| 10 | Cala Health Developer of a wearable non-invasive neuromodulation device 60Funding top 17%Product top 21%Innovation top 22%Patents top 26% All 11 signals ▾Fundingtop 17% Producttop 21% Innovationtop 22% Patentstop 26% Moattop 26% Talenttop 38% Techtop 46% Growthbottom 44% Marketbottom 43% Globalbottom 42% Newsbottom 21% Funding: Raised $157M across 7 rounds · 7 rounds over 13 yrs (0.5/yr) Product: 6 distinct product lines · Company stage: Series D rank vs industry peers · Fliar Intelligence Index 60/100 | $157M | 1 mo ago | 50 50 → 122 (+144%) · sector median +84% | Kate Rosenbluth Founder and Co-President | WordPressApple iCloud MailGoogle Workspace+31 | — | 243 patents Wearable peripheral nerve stimulation devices for tremor, movement and musculoskeletal disorder therapy | 1 award |
| 11 | Vital Connect Developer of biosensor patch for body vitals monitoring 64Product top 18%Funding top 21%Moat top 26%Patents top 32% All 11 signals ▾Producttop 18% Fundingtop 21% Moattop 26% Patentstop 32% Talenttop 34% Innovationtop 36% Growthtop 43% Techtop 45% Markettop 49% Globalbottom 47% Newsbottom 18% Product: 6 distinct product lines · Company stage: Series G Funding: Raised $140M across 8 rounds · 8 rounds over 15 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 64/100 | $140M | 15 mo ago | 184 184 → 199 (+8%) · sector median +84% | Nersi Nazari Founder | WordPressMySQLPHP+26 | — | 239 patents Wearable biosensor systems for continuous cardiovascular and vital‑sign monitoring | — |
| 12 | BigHealth CBT therapy for insomnia patients 69Tech top 14%Funding top 23%Moat top 31%News top 36% All 11 signals ▾Techtop 14% Fundingtop 23% Moattop 31% Newstop 36% Markettop 37% Talenttop 38% Producttop 40% Growthtop 44% Fin. healthtop 44% Globalbottom 45% Customersbottom 1% Tech: 62 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Funding: Raised $129M across 5 rounds · 5 rounds over 12 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 69/100 | $129M | 4 mo ago | 251 251 → 156 (-38%) · sector median +84% | Colin Espie Co-Founder | WebflowApple iCloud MailGoogle Workspace+22 | — | — | 1 partnership |
| 13 | Join Midi 🦄 Provider of a virtual care platform focused on female midlife health 80Funding top 14%Growth top 15%News top 20%Tech top 26% All 10 signals ▾Fundingtop 14% Growthtop 15% Newstop 20% Techtop 26% Producttop 33% Markettop 39% Innovationtop 40% Moattop 47% Talentbottom 49% Globalbottom 32% Funding: Raised $104M across 6 rounds · 6 rounds over 4 yrs (1.5/yr) Growth: Web rank 500,000 → 50,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 80/100 | $104M | 4 mo ago | 52 | Joanna Strober Founder | Cart FunctionalityShopifyShop Pay+20 | — | — | — |
| 14 | Openwater Provider of imaging technologies for medical diagnosis and treatments | $100M | 21 mo ago | — | Mary Lou Jepsen Founder & CEO | Wix eCommerceCart FunctionalityWix+17 | — | — | — |
| 15 | Onera Developer of a wearable sleep monitoring system | $60M | 29 mo ago | 50 | Pieter Ermers VP Research and Development & Founder | WebflowApple iCloud MailMicrosoft 365+14 | — | — | 1 partnership |
| 16 | Allez Health Developing biosensor technologies in the field of continuous glucose monitoring | $60M | 24 mo ago | — | Ted Zhang Co-founder & Chief Scientific Officer | — | — | — | — |
| 17 | SafelyYou Provider of AI-based solutions for senior care and fall management 64Product top 25%Funding top 26%Tech top 26%AI top 30% All 12 signals ▾Producttop 25% Fundingtop 26% Techtop 26% AItop 30% Moattop 35% Innovationtop 44% Growthtop 47% Patentstop 49% Talentbottom 49% Marketbottom 45% Globalbottom 39% Newsbottom 18% Product: 8 distinct product lines · Company stage: Series C Funding: Raised $59.5M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 64/100 | $60M | 16 mo ago | 85 85 → 191 (+125%) · sector median +84% | George Netscher Co-Founder & CEO | WordPressApple iCloud MailGoogle Workspace+34 | — | 4 patents Remote monitoring and communication system for cognitive care event management | — |
| 18 | Freespira Medical device & Mobile app to treat panic disorders | $49M | 26 mo ago | 25 25 → 41 (+64%) · sector median +84% | Debra Reisenthel Founding CEO; Director | WordPressMySQLPHP+33 | — | 6 patents Quantitative colorimetric capnometry sensors for non‑invasive CO₂ respiratory monitoring | — |
| 19 | Wildflower Health App to identify high risk pregnancies & assistance | $41M | 18 mo ago | 73 | Leah Sparks CEO & Founder | Wix eCommerceWixSentry+17 | — | — | — |
| 20 | Signos Provider of a wearable device for blood glucose pattern monitoring 42Tech top 20%Funding top 25%Moat top 39%Customers top 44% All 10 signals ▾Techtop 20% Fundingtop 25% Moattop 39% Customerstop 44% Producttop 46% Talentbottom 49% Marketbottom 40% Globalbottom 36% Growthbottom 31% Newsbottom 22% Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services Funding: Raised $37.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $37M | 0 mo ago | 30 | Sharam Fouladgar-Mercer Co-Founder & CEO | Webflow EcommerceWebflowGSAP+27 | — | — | — |
| 21 | Siren Provides smart socks for preventing diabetic foot ulcers 42Talent top 28%Funding top 29%Growth top 35%Product top 46% All 7 signals ▾Talenttop 28% Fundingtop 29% Growthtop 35% Producttop 46% Techbottom 45% Globalbottom 39% Marketbottom 25% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $30.9M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $31M | 17 mo ago | 22 | Henk Scholten Co-Founder & COO | WebflowMicrosoft AdvertisingPriority Hints+14 | — | — | — |
| 22 | Feel Therapeutics Provider of digital Precision Medicine company leveraging objective data and passive measurement for mental… 27Funding top 31%Talent top 38%Product bottom 48%Global bottom 39% All 6 signals ▾Fundingtop 31% Talenttop 38% Productbottom 48% Globalbottom 39% Techbottom 37% Marketbottom 31% Funding: Raised $30.0M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 27/100 | $30M | 23 mo ago | 34 | George Eleftheriou Co-Founder & CEO | WebflowCalendlyjQuery+8 | — | — | — |
| 23 | 9amHealth Provider of whole-body approach to healthcare delivering multiple services 55Funding top 26%Talent top 28%Growth top 35%Tech top 38% All 10 signals ▾Fundingtop 26% Talenttop 28% Growthtop 35% Techtop 38% Producttop 46% Moattop 48% Marketbottom 39% Globalbottom 37% Newsbottom 22% Customersbottom 14% Funding: Raised $29.8M across 2 rounds · 2 rounds over 4 yrs (0.5/yr) Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 55/100 | $30M | 3 mo ago | 35 | Paul Geevarghese Co-Founder & COO | SanityHubSpot CMS HubApple iCloud Mail+20 | — | — | — |
| 24 | Raydiant Oximetry Developer of noninvasive sensor technology for fetal oxygen level monitoring | $26M | 24 mo ago | 24 | Neil Ray Founder & CEO | — | — | 97 patents Non-invasive fetal and uterine oxygenation monitoring using trans-abdominal optical sensors | — |
| 25 | SafeinHome A home monitoring system for the elderly 57Growth top 21%Funding top 30%Product top 36%Moat top 42% All 8 signals ▾Growthtop 21% Fundingtop 30% Producttop 36% Moattop 42% Techtop 50% Talentbottom 49% Marketbottom 44% Globalbottom 29% Growth: Headcount 53 → 110 (+108%) across vintages · Fresh capital in last 24 mo Funding: Raised $25.0M across 1 rounds · 1 rounds over 9 yrs (0.1/yr) rank vs industry peers · Fliar Intelligence Index 57/100 | $25M | 6 mo ago | 110 110 → 150 (+36%) · sector median +84% | Ken Traverso Chief Executive Officer | WordPressMySQLPHP+26 | — | — | — |
| 26 | Ria Health Offers personalized medical treatment to control alcohol consumption | $18M | 15 mo ago | 33 33 → 82 (+148%) · sector median +84% | John Mendelson Co-Founder & CMO | WordPressApple iCloud MailGoogle Workspace+23 | — | — | — |
| 27 | Sensydia Cardio-respiratory monitoring device 27Funding top 36%Product top 36%Moat top 38%Innovation top 44% All 10 signals ▾Fundingtop 36% Producttop 36% Moattop 38% Innovationtop 44% Talentbottom 49% Patentsbottom 48% Techbottom 44% Globalbottom 33% Marketbottom 22% Newsbottom 22% Funding: Raised $17.8M across 7 rounds · 7 rounds over 10 yrs (0.7/yr) Product: 6 distinct product lines · Company stage: Series A rank vs industry peers · Fliar Intelligence Index 27/100 | $18M | 14 mo ago | 8 | Anthony Arnold President & Chief Executive Officer | — | — | 4 patents Non‑invasive cardiac acoustic analysis and multi‑sensor pulmonary pressure monitoring devices | — |
| 28 | Adaptyx Biosciences Platform offering microneedle sensor patch 27Funding top 44%Talent bottom 49%Tech bottom 41%Global bottom 36% All 4 signals ▾Fundingtop 44% Talentbottom 49% Techbottom 41% Globalbottom 36% Funding: Raised $14.2M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 27/100 | $14M | 7 mo ago | — | Alex Yoshikawa Co-Founder | WebflowThree.jsGSAP+16 | — | — | 1 award |
| 29 | Laxmi Therapeutic Devices Develper of a wearable diagnostic device for continuous glucose monitoring | $14M | 22 mo ago | 38 38 → 30 (-21%) · sector median +84% | Bill Antwerp Co-Founder | — | — | — | — |
| 30 | NextSense Developer of wireless earbuds that monitor brain activity and enhance sleep 48Innovation top 30%Patents top 30%Funding top 33%Tech top 36% All 9 signals ▾Innovationtop 30% Patentstop 30% Fundingtop 33% Techtop 36% Newstop 46% Moattop 47% Talentbottom 49% Globalbottom 36% Marketbottom 30% Innovation: 38 patents (top 37% of patent-holders) · 33 filings since 2022 vs 5 in 2017-21 Patents: 38 patents matched (strict assignee match) · 33 filings since 2022 vs 5 in 2017-21 rank vs industry peers · Fliar Intelligence Index 48/100 | $13M | 7 mo ago | 20 | Jonathan Berent CEO & Founder | Cart FunctionalityShopifyApple iCloud Mail+32 | — | 38 patents Ear‑mounted wearable biosensing and nerve‑stimulation devices for health monitoring and control | 1 launch |
| 31 | BrainHQ Online brain training platform for cognitive improvement and brain health 45Funding top 34%Tech top 36%Talent top 38%Growth top 47% All 9 signals ▾Fundingtop 34% Techtop 36% Talenttop 38% Growthtop 47% Moattop 48% Productbottom 48% Marketbottom 38% Customersbottom 38% Globalbottom 32% Funding: Raised $11.8M across 9 rounds · 9 rounds over 17 yrs (0.5/yr) Tech: 43 technologies across 5/8 capability areas · Cloud: Amazon S3, Amazon Ses rank vs industry peers · Fliar Intelligence Index 45/100 | $12M | 10 mo ago | 31 | Michael Merzenich Co-Founder & CSO | WordPressApple iCloud MailGoogle Workspace+33 | — | — | — |
| 32 | Malama Health Provider of an app for women to manage gestational diabetes 50Growth top 32%Funding top 36%Talent top 38%Tech top 46% All 8 signals ▾Growthtop 32% Fundingtop 36% Talenttop 38% Techtop 46% Customersbottom 48% Productbottom 40% Globalbottom 37% Marketbottom 36% Growth: Headcount 36 → 52 (+44%) across vintages · Fresh capital in last 24 mo Funding: Raised $9.3M across 3 rounds · 3 rounds over 1 yrs (3.0/yr) rank vs industry peers · Fliar Intelligence Index 50/100 | $9M | 3 mo ago | 52 | Orlando Li Co-Founder & CTO | Cart FunctionalitySquarespace CommerceSquarespace+17 | — | — | — |
| 33 | Level Zero Health Developer of biosensor technology for continuous hormone monitoring | $7M | 15 mo ago | — | Irene Jia Co-Founder & CTO | WebflowThree.jsMicrosoft 365+10 | — | — | — |
| 34 | Rosebud AI-powered journaling app for mental health and personal growth | $7M | 14 mo ago | 2 | Sean Dadashi Co-Founder | SentryZendeskNode.js+20 | — | — | — |
| 35 | Delfina AI-assisted software for monitoring pregnancy and infants' health | $6M | 13 mo ago | 30 | Eliza Nguyen Md Mph Co-Founder | Webflowcore-jsjQuery+18 | — | — | 2 job openings · 2 partnerships |
| 36 | Smartlens Provider of a non-invasive device for measuring eye pressure (IOP) | $6M | 8 mo ago | 7 | Murat Baday Co-Founder | WixSentryBootstrap+10 | — | 52 patents Smart contact lenses with embedded microfluidic/optical sensors for intraocular pressure monitoring | — |
| 37 | PyrAmes Developer of a non-invasive blood pressure monitoring system for babies | $6M | 10 mo ago | 13 | Zhenan Bao Co-Founder | WordPressMySQLPHP+26 | — | 4 patents Patents concentrated in health & consumer products | — |
| 38 | IMS Provider of a wearable smart sensor for glucose monitoring | $5M | 10 mo ago | 5 | Muhammad U Rahman Founder | — | — | 72 patents Vehicle telematics and driver behavior analytics, including OBD, smartphone integration, and traffic alerts | — |
| 39 | IPill Dispenser Developer of iPill dispenser app and device | $5M | 12 mo ago | 4 | John Hsu Founder & CEO | — | — | — | — |
| 40 | kegg Manufacturer of medical devices for tracking cervical mucus fertility metrics | $4M | 17 mo ago | 6 | Kristina Cahojova Founder & CEO | Cart FunctionalityShopifyShop Pay+29 | — | — | 1 expansion |
| 41 | Sensate Developer of a relaxation device for stress and anxiety management | $4M | 18 mo ago | 5 | Anna Gudmundson Co-Founder & CEO | Cart FunctionalityShopifyTailwind CSS+32 | — | 3 patents Electrical overcurrent and thermal protection devices for circuits | — |
| 42 | Persperion Diagnostics Developer of medical device fo sweat analysis | $4M | 13 mo ago | 4 | Xinyu Liu Co-Founder | — | — | — | — |
| 43 | CognifiSense Developer of virtual reality therapy for chronic pain management 13Moat top 32%Talent top 35%Patents top 44%Funding bottom 49% All 8 signals ▾Moattop 32% Talenttop 35% Patentstop 44% Fundingbottom 49% Innovationbottom 41% Globalbottom 35% Techbottom 34% Marketbottom 8% Moat: Editorial + unicorn rating 5/10 · IP moat: 26 patents Talent: 3 named leaders on record rank vs industry peers · Fliar Intelligence Index 13/100 | $3M | 14 mo ago | 2 | Harald Stock Co-Founder | — | — | 26 patents Integrated combinatorial analgesic therapies with physiological monitoring and symptom relief analytics | — |
| 44 | DUSQ Developer of sleep science studying recovery regulation under modern conditions 29Talent top 28%Funding bottom 47%Tech bottom 47%Global bottom 45% All 5 signals ▾Talenttop 28% Fundingbottom 47% Techbottom 47% Globalbottom 45% Marketbottom 31% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $2.6M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $3M | 4 mo ago | — | Siddhant Bhargava Co-Founder & CEO | Cart FunctionalityShopifySentry+17 | — | — | — |
| 45 | AudioCardio Mobile application providing sound therapy | $2M | 3 mo ago | 4 | Sam Kwak Founder / CSO | WordPressMySQLPHP+38 | — | — | — |
| 46 | Storx Technologies Developer of a non-invasive fetal monitoring device | $1M | 13 mo ago | 3 | Soheil Ghiasi Co-Founder | — | — | — | — |
| 47 | Advanced Brain Monitoring Provider of neuro-diagnostics devices for researchers and clinical trials | $1M | 9 mo ago | 41 | — | WebflowjQuery-pjaxMicrosoft Advertising+12 | — | 104 patents Neurodegenerative diagnostics, brain‑targeted personalized therapy, and precise positioning systems for neurosurgery | — |
| 48 | Welltory Online health and wellness tracking and training platform 62Customers top 13%Growth top 28%Tech top 37%Funding top 48% All 10 signals ▾Customerstop 13% Growthtop 28% Techtop 37% Fundingtop 48% Moattop 48% Talentbottom 49% Marketbottom 48% Productbottom 40% Globalbottom 38% Newsbottom 18% Customers: Play-Store rating 4.60★ across 58,346 ratings (1 apps) · Review volume +23% in 6 mo Growth: Web rank 5,000,000 → 1,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 62/100 | $1M | 7 mo ago | 76 | Jane Smorodnikova Co-Founder & CEO | SentryNode.jsAmazon Web Services+15 | — | — | — |
| 49 | Ohm Health Developer of a biofeedback lamp that guides breathing for nervous system balance 35Funding bottom 48%Tech bottom 48%Talent bottom 45%Global bottom 25% All 4 signals ▾Fundingbottom 48% Techbottom 48% Talentbottom 45% Globalbottom 25% Funding: Raised $737k across 2 rounds · 2 rounds over 1 yrs (2.0/yr) Tech: 22 technologies across 4/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 35/100 | $737K | 5 mo ago | — | James McGoff Founder | ShopifyWebflowVimeo+19 | — | — | — |
| 50 | Wearlinq Provider of wearable ECG monitoring device to detect heart disorders | $696K | 6 mo ago | — | Konrad Morzkowski Co-Founder & CEO | Node.jsReactNext.js App Router+9 | — | — | 1 launch |
Top 12 Disease Self Management companies in California
#1
Series D · Stanford, California · founded 2013 · 50 employees$157.1Mraised▾
Developer of a wearable non-invasive neuromodulation device. The company has developed a neuromodulation device that aims to provide relief of hand tremors in adults with essential tremors. It combines a watch-like device with an implantable sensor that externally stimulates peripheral nerves to reduce the same. The company has also developed a portable medical device with sensors to monitor the physical movement of a patient wearing or carrying the device.
- Apr 2026Conventional Debt$50M
- Oct 2025Series D$50M
- Dec 2024Series D$50M
- May 2022Series D—
#2
Series C · San Francisco, California · founded 2010 · 251 employees$129.3Mraised▾
CBT therapy for insomnia patients. Its flagship product Sleepio is a digital sleep improvement program, clinically proven to help users overcome poor sleep. Its virtual sleep expert "The Prof" teaches users proven Cognitive Behavioral Therapy (CBT) techniques, personalized to their problems and monitors their progress. Sleepio has been validated in the world’s first placebo-controlled RCT for a digital sleep intervention.
- Feb 2026Series C$23.7M
- Jan 2022Series C$75M
- Jun 2020Series B$39M
- Jul 2016Series B$12M
#3
Series D · Los Altos Hills, California · founded 2021 · 52 employees$104Mraised▾
Provider of a virtual care platform focused on female midlife health
- Feb 2026Series D$100M
- Oct 2025Series C$50M
- Sep 2024Series B$5M
- Apr 2024Series B$60M
#4
Series B · San Francisco, California · founded 2020 · 30 employees$37Mraised▾
Provider of a wearable device for blood glucose pattern monitoring. The company has developed an app-based platform that recommends meals and exercises for users based on the glucose pattern detected through the connected device. The app provides real-time glucose monitoring and glucose spike levels for different foods. Based on this, personalized fitness and nutrition plan can be developed.
- Oct 2023Series B$20M
- Nov 2021Series A$13M
- Jan 2021Seed$4M
#5
Series B · Encinitas, California · founded 2021 · 35 employees$29.8Mraised▾
Provider of whole-body approach to healthcare delivering multiple services. The company's services include personalized care plans, prescription medication, at-home lab tests, virtual medical care, devices & supplies.
- Mar 2026Series B$26M
- Feb 2024Series A$9.5M
- Apr 2022Series A—
- 2021Seed—
#6
Series D · Oakland, California · founded 2012 · 95 employees$167Mraised▾
Eko offers an AI-based platform for remote monitoring of cardiac health. The solution offered by the company collects real-time patient data and analyses it to generate a report for doctors. The report generated aids in providing proper treatment to patients. The company has also developed products like Duo and Core stethoscopes for heart disease monitoring.
- Apr 2025Grant (prize money)$238.5K
- Jun 2024Series D$41M
- Sep 2022Grant (prize money)$2.3M
- Sep 2022Grant (prize money)$2.7M
#7
Seed · Stanford, California · founded 2022 · 52 employees$9.3Mraised▾
Provider of an app for women to manage gestational diabetes. The features of the app inlcude syncing glucose meters and automatically pulling in glucose levels. It uses AI to help identify food triggers for high blood glucose levels.
- Mar 2026Seed$5.9M
- Mar 2026Grant (prize money)$3.3M
- Seed$125K
#8
Series C · San Diego, California · founded 2012 · 91 employees$175.1Mraised▾
Provider of a wearable biosensor platform for diabetes monitoring. It offers a wireless microsensor that enables users to understand their metabolism and blood glucose levels in real-time.
- Mar 2025Series C$100M
- Dec 2023Series B$59.1M
- Nov 2021Series B$100M
- Sep 2021Grant (prize money)$1.9M
#9
Series D · Walnut Creek, California · founded 2012 · 110 employees$25Mraised▾
SafeinHome offers a home monitoring system for the elderly. The system uses small discreet sensors placed in the house to monitor activity and send alerts in case anything is abnormal. The system can monitor sleep, movement around the house and send alerts to family caregivers smartphones.
- Dec 2025Series D$25M
- Dec 2017Grant (prize money)—
#10
Series G · Campbell, California · founded 2011 · 184 employees$139.9Mraised▾
Developer of biosensor patch for body vitals monitoring. Its biosensor patch measures multiple parameters including heart rate, heart rate variability, respiratory rate, single-lead ECG, skin temperature, body posture, fall detection, and activities like step counting. It has applications for use in hospitals, homes, research facilities, HCPs, and care facilities.
- Feb 2025Conventional Debt—
- Feb 2025Series G$100M
- Jul 2023Series F$30M
- Sep 2022Series D—
#11
Series F · Palo Alto, California · founded 2010 · 121 employees$201Mraised▾
Glooko is a diabetes management solution for patients, health systems, and payer groups. Glooko’s products enable clinicians to remotely access their patients’ blood glucose readings and other related data, and optimize their insulin therapy. The company’s System allows people with diabetes to download their glucose readings to their mobile devices. According to the company, their population management web app offers diabetes-centric analytics and supplies insightful reports, graphs and pattern-triggered notifications to patients, health systems and payers. Partners include Abbott, Roche, LifeScan, Medtronic, Omnipod, Bayer, Nipro, and Arkray among others. Glooko and Diasend got merged in September 2016 and the combined companies operate under the Glooko moniker.
- Oct 2024Series F$100M
- Mar 2021Series D$30M
- Jun 2017Series C$35M
- Sep 2016Series B$8M
#12
Series A · Mountain View, California · founded 2020 · 20 employees$12.7Mraised▾
Developer of wireless earbuds that monitor brain activity and enhance sleep. The earbuds use sensors to capture brain rhythms and track body movement. They measure sleep metrics and provide an intelligent relaxation experience with science-backed audio. The product automatically pauses audio when sensors detect sleep.
- Nov 2025Series A$16M
- Apr 2024Series A$16.3M
- Nov 2023Seed$3M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding flat · growth flat
How research on Digital Health in California is moving
A read on the academic research around Digital Health in California — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 626 papers.
UCSF, UCLA, and UC San Diego lead California's digital-health research—dominated by mobile health, telehealth, and digital mental health—with a cautiously contested tone reflecting more concerns than breakthroughs.
- University of California, San Francisco154
- University of California, Los Angeles80
- University of California San Diego75
- University of California, Irvine73
- University of Southern California62
- Wearable computer2→14
- Health care1→13
- Health informatics4→9
- Telemedicine1→5
- Remote patient monitoring4→7
- Health care4→58
- Health informatics10→38
- mHealth2→25
- Psychological intervention1→23
- Public health3→20
- Health care4→47
- Health informatics11→53
- Public health3→34
- Health administration9→32
- Psychological intervention4→25