Radar Companies Disease Self Management · California
Radar · Disease Self Management in California

Best Disease Self Management Companies in California, United States

The 936 best Disease Self Management companies in California, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Jawbone.

936companies tracked
$10.1Bdisclosed funding
7unicorns
379have raised
FLIAR INTELLIGENCE · DISEASE SELF MANAGEMENT × CALIFORNIA

Our analysis of 50 Disease Self Management companies

$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.

50companies analysed
94%cloud-native stacks
2025funding peak (by rounds)
3unicorns
2014median founding year
1.1Mcombined LinkedIn audience
78%of audience held by top 3
6companies hiring publicly (12 mo)

Ranked: Best Disease Self Management companies in California

#CompanyDisclosed fundingLast roundEmployeesFounderTech stackApp-install YoYPatents & IP focusRecent signals
1Jawbone 🦄
Provider of wearable devices for activity and sleep tracking
$877M125 mo ago50Squarespace CommerceSquarespaceTypeScript+13
2Cue Health
Provider of health monitoring system for diagnosing diseases like influenza
$406M61 mo ago726123 patents
Rapid point‑of‑care molecular diagnostics and sample collection devices for analyte detection
3Virta 🦄
Provider of therapies for metabolic health in chronic disease patients
$402M61 mo ago443
443 → 902 (+104%) · sector median +84%
Jeff Volek
Co-Founder & Chief Science Officer
WebflowSalesforceVideoJS+29+60%3 patents
Cable‑suspended ground transport and overland conveyor systems for material handling
4Willow
Wearable double electric breast pump kits
$228M29 mo ago109John Chang
Co-Founder & Chief Technical Officer
Amazon WebstoreCart FunctionalityShopify+3416 patents
Patents concentrated in electrical & electronics
5Eargo
Provider of hearing aids for people with hearing disabilities
$217M47 mo ago45Florent Michel
Co-Founder
Apple iCloud MailGoogle WorkspaceNode.js+2892 patents
Wireless-enabled hearing aid devices, charging, tip customization, and diagnostic testing solutions
1 award
6Glooko
Glucose meter and mobile app for diabetes management
53Funding top 18%Product top 27%Tech top 29%Moat top 35%
All 12 signals ▾
Fundingtop 18%
Producttop 27%
Techtop 29%
Moattop 35%
Growthtop 43%
Markettop 46%
Talentbottom 49%
Globalbottom 47%
Customersbottom 40%
Patentsbottom 34%
Innovationbottom 30%
Newsbottom 20%
Funding: Raised $201M across 8 rounds · 8 rounds over 15 yrs (0.5/yr)
Product: 2 published apps (452k installs) · Company stage: Series F
rank vs industry peers · Fliar Intelligence Index 53/100
$201M20 mo ago121
121 → 237 (+96%) · sector median +84%
Mike Alvarez
CEO
WordPress Block EditorWordPressApple iCloud Mail+38+29%5 patents
Digital diabetes management: glucose data analytics and personalized activity recommendation systems.
2 launchs
7Headspace 🦄
Provider of mental health support services via application and human care
76Customers top 21%Tech top 22%Funding top 25%Moat top 26%
All 11 signals ▾
Customerstop 21%
Techtop 22%
Fundingtop 25%
Moattop 26%
Talenttop 28%
Markettop 31%
Producttop 35%
AItop 45%
Globalbottom 46%
Growthbottom 29%
Newsbottom 24%
Customers: Play-Store rating 4.27★ across 339,862 ratings (2 apps) · Review volume +3% in 6 mo
Tech: 58 technologies across 7/8 capability areas · Cloud: Amazon Alb, Amazon Cloudfront
rank vs industry peers · Fliar Intelligence Index 76/100
$178M34 mo ago906
906 → 1,557 (+72%) · sector median +84%
Andy Puddicombe
Co-Founder
Cart FunctionalityContentfulTurbopack+23+9%
8Biolinq
Provider of a wearable biosensor platform for diabetes monitoring
67Innovation top 13%Funding top 17%Patents top 17%Moat top 26%
All 10 signals ▾
Innovationtop 13%
Fundingtop 17%
Patentstop 17%
Moattop 26%
Talenttop 38%
Growthtop 45%
Marketbottom 45%
Globalbottom 43%
Techbottom 39%
Newsbottom 18%
Innovation: 189 patents (top 11% of patent-holders) · 161 filings since 2022 vs 28 in 2017-21
Funding: Raised $175M across 15 rounds · 15 rounds over 12 yrs (1.2/yr)
rank vs industry peers · Fliar Intelligence Index 67/100
$175M15 mo ago91Jared Tangney
Co-Founder
Webflowcore-jsjQuery+11189 patents
Minimally invasive microneedle-based continuous biosensing for interstitial fluid analytes
9Eko
Provider of AI-based remote patient monitoring platform for cardiac health
72Funding top 16%Customers top 22%Tech top 25%Product top 30%
All 11 signals ▾
Fundingtop 16%
Customerstop 22%
Techtop 25%
Producttop 30%
Moattop 31%
Talenttop 43%
AItop 45%
Markettop 48%
Globalbottom 45%
Growthbottom 44%
Newsbottom 20%
Funding: Raised $167M across 16 rounds · 16 rounds over 11 yrs (1.5/yr)
Customers: Play-Store rating 4.81★ across 4,901 ratings (2 apps) · Review volume +17% in 6 mo
rank vs industry peers · Fliar Intelligence Index 72/100
$167M14 mo ago95
95 → 204 (+115%) · sector median +84%
Jason Bellet
Co-Founder
Cart FunctionalityShopifyApple iCloud Mail+40+43%1 launch
10Cala Health
Developer of a wearable non-invasive neuromodulation device
60Funding top 17%Product top 21%Innovation top 22%Patents top 26%
All 11 signals ▾
Fundingtop 17%
Producttop 21%
Innovationtop 22%
Patentstop 26%
Moattop 26%
Talenttop 38%
Techtop 46%
Growthbottom 44%
Marketbottom 43%
Globalbottom 42%
Newsbottom 21%
Funding: Raised $157M across 7 rounds · 7 rounds over 13 yrs (0.5/yr)
Product: 6 distinct product lines · Company stage: Series D
rank vs industry peers · Fliar Intelligence Index 60/100
$157M1 mo ago50
50 → 122 (+144%) · sector median +84%
Kate Rosenbluth
Founder and Co-President
WordPressApple iCloud MailGoogle Workspace+31243 patents
Wearable peripheral nerve stimulation devices for tremor, movement and musculoskeletal disorder therapy
1 award
11Vital Connect
Developer of biosensor patch for body vitals monitoring
64Product top 18%Funding top 21%Moat top 26%Patents top 32%
All 11 signals ▾
Producttop 18%
Fundingtop 21%
Moattop 26%
Patentstop 32%
Talenttop 34%
Innovationtop 36%
Growthtop 43%
Techtop 45%
Markettop 49%
Globalbottom 47%
Newsbottom 18%
Product: 6 distinct product lines · Company stage: Series G
Funding: Raised $140M across 8 rounds · 8 rounds over 15 yrs (0.5/yr)
rank vs industry peers · Fliar Intelligence Index 64/100
$140M15 mo ago184
184 → 199 (+8%) · sector median +84%
Nersi Nazari
Founder
WordPressMySQLPHP+26239 patents
Wearable biosensor systems for continuous cardiovascular and vital‑sign monitoring
12BigHealth
CBT therapy for insomnia patients
69Tech top 14%Funding top 23%Moat top 31%News top 36%
All 11 signals ▾
Techtop 14%
Fundingtop 23%
Moattop 31%
Newstop 36%
Markettop 37%
Talenttop 38%
Producttop 40%
Growthtop 44%
Fin. healthtop 44%
Globalbottom 45%
Customersbottom 1%
Tech: 62 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3
Funding: Raised $129M across 5 rounds · 5 rounds over 12 yrs (0.4/yr)
rank vs industry peers · Fliar Intelligence Index 69/100
$129M4 mo ago251
251 → 156 (-38%) · sector median +84%
Colin Espie
Co-Founder
WebflowApple iCloud MailGoogle Workspace+221 partnership
13Join Midi 🦄
Provider of a virtual care platform focused on female midlife health
80Funding top 14%Growth top 15%News top 20%Tech top 26%
All 10 signals ▾
Fundingtop 14%
Growthtop 15%
Newstop 20%
Techtop 26%
Producttop 33%
Markettop 39%
Innovationtop 40%
Moattop 47%
Talentbottom 49%
Globalbottom 32%
Funding: Raised $104M across 6 rounds · 6 rounds over 4 yrs (1.5/yr)
Growth: Web rank 500,000 → 50,000 YoY · Fresh capital in last 24 mo
rank vs industry peers · Fliar Intelligence Index 80/100
$104M4 mo ago52Joanna Strober
Founder
Cart FunctionalityShopifyShop Pay+20
14Openwater
Provider of imaging technologies for medical diagnosis and treatments
$100M21 mo agoMary Lou Jepsen
Founder & CEO
Wix eCommerceCart FunctionalityWix+17
15Onera
Developer of a wearable sleep monitoring system
$60M29 mo ago50Pieter Ermers
VP Research and Development & Founder
WebflowApple iCloud MailMicrosoft 365+141 partnership
16Allez Health
Developing biosensor technologies in the field of continuous glucose monitoring
$60M24 mo agoTed Zhang
Co-founder & Chief Scientific Officer
17SafelyYou
Provider of AI-based solutions for senior care and fall management
64Product top 25%Funding top 26%Tech top 26%AI top 30%
All 12 signals ▾
Producttop 25%
Fundingtop 26%
Techtop 26%
AItop 30%
Moattop 35%
Innovationtop 44%
Growthtop 47%
Patentstop 49%
Talentbottom 49%
Marketbottom 45%
Globalbottom 39%
Newsbottom 18%
Product: 8 distinct product lines · Company stage: Series C
Funding: Raised $59.5M across 6 rounds · 6 rounds over 9 yrs (0.7/yr)
rank vs industry peers · Fliar Intelligence Index 64/100
$60M16 mo ago85
85 → 191 (+125%) · sector median +84%
George Netscher
Co-Founder & CEO
WordPressApple iCloud MailGoogle Workspace+344 patents
Remote monitoring and communication system for cognitive care event management
18Freespira
Medical device & Mobile app to treat panic disorders
$49M26 mo ago25
25 → 41 (+64%) · sector median +84%
Debra Reisenthel
Founding CEO; Director
WordPressMySQLPHP+336 patents
Quantitative colorimetric capnometry sensors for non‑invasive CO₂ respiratory monitoring
19Wildflower Health
App to identify high risk pregnancies & assistance
$41M18 mo ago73Leah Sparks
CEO & Founder
Wix eCommerceWixSentry+17
20Signos
Provider of a wearable device for blood glucose pattern monitoring
42Tech top 20%Funding top 25%Moat top 39%Customers top 44%
All 10 signals ▾
Techtop 20%
Fundingtop 25%
Moattop 39%
Customerstop 44%
Producttop 46%
Talentbottom 49%
Marketbottom 40%
Globalbottom 36%
Growthbottom 31%
Newsbottom 22%
Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services
Funding: Raised $37.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr)
rank vs industry peers · Fliar Intelligence Index 42/100
$37M0 mo ago30Sharam Fouladgar-Mercer
Co-Founder & CEO
Webflow EcommerceWebflowGSAP+27
21Siren
Provides smart socks for preventing diabetic foot ulcers
42Talent top 28%Funding top 29%Growth top 35%Product top 46%
All 7 signals ▾
Talenttop 28%
Fundingtop 29%
Growthtop 35%
Producttop 46%
Techbottom 45%
Globalbottom 39%
Marketbottom 25%
Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
Funding: Raised $30.9M across 8 rounds · 8 rounds over 11 yrs (0.7/yr)
rank vs industry peers · Fliar Intelligence Index 42/100
$31M17 mo ago22Henk Scholten
Co-Founder & COO
WebflowMicrosoft AdvertisingPriority Hints+14
22Feel Therapeutics
Provider of digital Precision Medicine company leveraging objective data and passive measurement for mental…
27Funding top 31%Talent top 38%Product bottom 48%Global bottom 39%
All 6 signals ▾
Fundingtop 31%
Talenttop 38%
Productbottom 48%
Globalbottom 39%
Techbottom 37%
Marketbottom 31%
Funding: Raised $30.0M across 6 rounds · 6 rounds over 10 yrs (0.6/yr)
Talent: 2 named leaders on record · 2 C-suite/founder profiles curated
rank vs industry peers · Fliar Intelligence Index 27/100
$30M23 mo ago34George Eleftheriou
Co-Founder & CEO
WebflowCalendlyjQuery+8
239amHealth
Provider of whole-body approach to healthcare delivering multiple services
55Funding top 26%Talent top 28%Growth top 35%Tech top 38%
All 10 signals ▾
Fundingtop 26%
Talenttop 28%
Growthtop 35%
Techtop 38%
Producttop 46%
Moattop 48%
Marketbottom 39%
Globalbottom 37%
Newsbottom 22%
Customersbottom 14%
Funding: Raised $29.8M across 2 rounds · 2 rounds over 4 yrs (0.5/yr)
Talent: 4 named leaders on record · 4 C-suite/founder profiles curated
rank vs industry peers · Fliar Intelligence Index 55/100
$30M3 mo ago35Paul Geevarghese
Co-Founder & COO
SanityHubSpot CMS HubApple iCloud Mail+20
24Raydiant Oximetry
Developer of noninvasive sensor technology for fetal oxygen level monitoring
$26M24 mo ago24Neil Ray
Founder & CEO
97 patents
Non-invasive fetal and uterine oxygenation monitoring using trans-abdominal optical sensors
25SafeinHome
A home monitoring system for the elderly
57Growth top 21%Funding top 30%Product top 36%Moat top 42%
All 8 signals ▾
Growthtop 21%
Fundingtop 30%
Producttop 36%
Moattop 42%
Techtop 50%
Talentbottom 49%
Marketbottom 44%
Globalbottom 29%
Growth: Headcount 53 → 110 (+108%) across vintages · Fresh capital in last 24 mo
Funding: Raised $25.0M across 1 rounds · 1 rounds over 9 yrs (0.1/yr)
rank vs industry peers · Fliar Intelligence Index 57/100
$25M6 mo ago110
110 → 150 (+36%) · sector median +84%
Ken Traverso
Chief Executive Officer
WordPressMySQLPHP+26
26Ria Health
Offers personalized medical treatment to control alcohol consumption
$18M15 mo ago33
33 → 82 (+148%) · sector median +84%
John Mendelson
Co-Founder & CMO
WordPressApple iCloud MailGoogle Workspace+23
27Sensydia
Cardio-respiratory monitoring device
27Funding top 36%Product top 36%Moat top 38%Innovation top 44%
All 10 signals ▾
Fundingtop 36%
Producttop 36%
Moattop 38%
Innovationtop 44%
Talentbottom 49%
Patentsbottom 48%
Techbottom 44%
Globalbottom 33%
Marketbottom 22%
Newsbottom 22%
Funding: Raised $17.8M across 7 rounds · 7 rounds over 10 yrs (0.7/yr)
Product: 6 distinct product lines · Company stage: Series A
rank vs industry peers · Fliar Intelligence Index 27/100
$18M14 mo ago8Anthony Arnold
President & Chief Executive Officer
4 patents
Non‑invasive cardiac acoustic analysis and multi‑sensor pulmonary pressure monitoring devices
28Adaptyx Biosciences
Platform offering microneedle sensor patch
27Funding top 44%Talent bottom 49%Tech bottom 41%Global bottom 36%
All 4 signals ▾
Fundingtop 44%
Talentbottom 49%
Techbottom 41%
Globalbottom 36%
Funding: Raised $14.2M across 2 rounds · 2 rounds over 1 yrs (2.0/yr)
Talent: 1 named leader on record · 1 C-suite/founder profile curated
rank vs industry peers · Fliar Intelligence Index 27/100
$14M7 mo agoAlex Yoshikawa
Co-Founder
WebflowThree.jsGSAP+161 award
29Laxmi Therapeutic Devices
Develper of a wearable diagnostic device for continuous glucose monitoring
$14M22 mo ago38
38 → 30 (-21%) · sector median +84%
Bill Antwerp
Co-Founder
30NextSense
Developer of wireless earbuds that monitor brain activity and enhance sleep
48Innovation top 30%Patents top 30%Funding top 33%Tech top 36%
All 9 signals ▾
Innovationtop 30%
Patentstop 30%
Fundingtop 33%
Techtop 36%
Newstop 46%
Moattop 47%
Talentbottom 49%
Globalbottom 36%
Marketbottom 30%
Innovation: 38 patents (top 37% of patent-holders) · 33 filings since 2022 vs 5 in 2017-21
Patents: 38 patents matched (strict assignee match) · 33 filings since 2022 vs 5 in 2017-21
rank vs industry peers · Fliar Intelligence Index 48/100
$13M7 mo ago20Jonathan Berent
CEO & Founder
Cart FunctionalityShopifyApple iCloud Mail+3238 patents
Ear‑mounted wearable biosensing and nerve‑stimulation devices for health monitoring and control
1 launch
31BrainHQ
Online brain training platform for cognitive improvement and brain health
45Funding top 34%Tech top 36%Talent top 38%Growth top 47%
All 9 signals ▾
Fundingtop 34%
Techtop 36%
Talenttop 38%
Growthtop 47%
Moattop 48%
Productbottom 48%
Marketbottom 38%
Customersbottom 38%
Globalbottom 32%
Funding: Raised $11.8M across 9 rounds · 9 rounds over 17 yrs (0.5/yr)
Tech: 43 technologies across 5/8 capability areas · Cloud: Amazon S3, Amazon Ses
rank vs industry peers · Fliar Intelligence Index 45/100
$12M10 mo ago31Michael Merzenich
Co-Founder & CSO
WordPressApple iCloud MailGoogle Workspace+33
32Malama Health
Provider of an app for women to manage gestational diabetes
50Growth top 32%Funding top 36%Talent top 38%Tech top 46%
All 8 signals ▾
Growthtop 32%
Fundingtop 36%
Talenttop 38%
Techtop 46%
Customersbottom 48%
Productbottom 40%
Globalbottom 37%
Marketbottom 36%
Growth: Headcount 36 → 52 (+44%) across vintages · Fresh capital in last 24 mo
Funding: Raised $9.3M across 3 rounds · 3 rounds over 1 yrs (3.0/yr)
rank vs industry peers · Fliar Intelligence Index 50/100
$9M3 mo ago52Orlando Li
Co-Founder & CTO
Cart FunctionalitySquarespace CommerceSquarespace+17
33Level Zero Health
Developer of biosensor technology for continuous hormone monitoring
$7M15 mo agoIrene Jia
Co-Founder & CTO
WebflowThree.jsMicrosoft 365+10
34Rosebud
AI-powered journaling app for mental health and personal growth
$7M14 mo ago2Sean Dadashi
Co-Founder
SentryZendeskNode.js+20
35Delfina
AI-assisted software for monitoring pregnancy and infants' health
$6M13 mo ago30Eliza Nguyen Md Mph
Co-Founder
Webflowcore-jsjQuery+182 job openings · 2 partnerships
36Smartlens
Provider of a non-invasive device for measuring eye pressure (IOP)
$6M8 mo ago7Murat Baday
Co-Founder
WixSentryBootstrap+1052 patents
Smart contact lenses with embedded microfluidic/optical sensors for intraocular pressure monitoring
37PyrAmes
Developer of a non-invasive blood pressure monitoring system for babies
$6M10 mo ago13Zhenan Bao
Co-Founder
WordPressMySQLPHP+264 patents
Patents concentrated in health & consumer products
38IMS
Provider of a wearable smart sensor for glucose monitoring
$5M10 mo ago5Muhammad U Rahman
Founder
72 patents
Vehicle telematics and driver behavior analytics, including OBD, smartphone integration, and traffic alerts
39IPill Dispenser
Developer of iPill dispenser app and device
$5M12 mo ago4John Hsu
Founder & CEO
40kegg
Manufacturer of medical devices for tracking cervical mucus fertility metrics
$4M17 mo ago6Kristina Cahojova
Founder & CEO
Cart FunctionalityShopifyShop Pay+291 expansion
41Sensate
Developer of a relaxation device for stress and anxiety management
$4M18 mo ago5Anna Gudmundson
Co-Founder & CEO
Cart FunctionalityShopifyTailwind CSS+323 patents
Electrical overcurrent and thermal protection devices for circuits
42Persperion Diagnostics
Developer of medical device fo sweat analysis
$4M13 mo ago4Xinyu Liu
Co-Founder
43CognifiSense
Developer of virtual reality therapy for chronic pain management
13Moat top 32%Talent top 35%Patents top 44%Funding bottom 49%
All 8 signals ▾
Moattop 32%
Talenttop 35%
Patentstop 44%
Fundingbottom 49%
Innovationbottom 41%
Globalbottom 35%
Techbottom 34%
Marketbottom 8%
Moat: Editorial + unicorn rating 5/10 · IP moat: 26 patents
Talent: 3 named leaders on record
rank vs industry peers · Fliar Intelligence Index 13/100
$3M14 mo ago2Harald Stock
Co-Founder
26 patents
Integrated combinatorial analgesic therapies with physiological monitoring and symptom relief analytics
44DUSQ
Developer of sleep science studying recovery regulation under modern conditions
29Talent top 28%Funding bottom 47%Tech bottom 47%Global bottom 45%
All 5 signals ▾
Talenttop 28%
Fundingbottom 47%
Techbottom 47%
Globalbottom 45%
Marketbottom 31%
Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
Funding: Raised $2.6M across 1 rounds · 1 rounds over 1 yrs (1.0/yr)
rank vs industry peers · Fliar Intelligence Index 29/100
$3M4 mo agoSiddhant Bhargava
Co-Founder & CEO
Cart FunctionalityShopifySentry+17
45AudioCardio
Mobile application providing sound therapy
$2M3 mo ago4Sam Kwak
Founder / CSO
WordPressMySQLPHP+38
46Storx Technologies
Developer of a non-invasive fetal monitoring device
$1M13 mo ago3Soheil Ghiasi
Co-Founder
47Advanced Brain Monitoring
Provider of neuro-diagnostics devices for researchers and clinical trials
$1M9 mo ago41WebflowjQuery-pjaxMicrosoft Advertising+12104 patents
Neurodegenerative diagnostics, brain‑targeted personalized therapy, and precise positioning systems for neurosurgery
48Welltory
Online health and wellness tracking and training platform
62Customers top 13%Growth top 28%Tech top 37%Funding top 48%
All 10 signals ▾
Customerstop 13%
Growthtop 28%
Techtop 37%
Fundingtop 48%
Moattop 48%
Talentbottom 49%
Marketbottom 48%
Productbottom 40%
Globalbottom 38%
Newsbottom 18%
Customers: Play-Store rating 4.60★ across 58,346 ratings (1 apps) · Review volume +23% in 6 mo
Growth: Web rank 5,000,000 → 1,000,000 YoY · Fresh capital in last 24 mo
rank vs industry peers · Fliar Intelligence Index 62/100
$1M7 mo ago76Jane Smorodnikova
Co-Founder & CEO
SentryNode.jsAmazon Web Services+15
49Ohm Health
Developer of a biofeedback lamp that guides breathing for nervous system balance
35Funding bottom 48%Tech bottom 48%Talent bottom 45%Global bottom 25%
All 4 signals ▾
Fundingbottom 48%
Techbottom 48%
Talentbottom 45%
Globalbottom 25%
Funding: Raised $737k across 2 rounds · 2 rounds over 1 yrs (2.0/yr)
Tech: 22 technologies across 4/8 capability areas · Cloud: Cloudflare
rank vs industry peers · Fliar Intelligence Index 35/100
$737K5 mo agoJames McGoff
Founder
ShopifyWebflowVimeo+19
50Wearlinq
Provider of wearable ECG monitoring device to detect heart disorders
$696K6 mo agoKonrad Morzkowski
Co-Founder & CEO
Node.jsReactNext.js App Router+91 launch

Top 12 Disease Self Management companies in California

#1
Series D · Stanford, California · founded 2013 · 50 employees
$157.1Mraised

Developer of a wearable non-invasive neuromodulation device. The company has developed a neuromodulation device that aims to provide relief of hand tremors in adults with essential tremors. It combines a watch-like device with an implantable sensor that externally stimulates peripheral nerves to reduce the same. The company has also developed a portable medical device with sensors to monitor the physical movement of a patient wearing or carrying the device.

Fliar Intelligence Index™ 60how this company ranks against its industry peers
Funding
top 17%
Product
top 21%
Innovation
top 22%
Patents
top 26%
Moat
top 26%
Talent
top 38%
Funding: Raised $157M across 7 rounds · 7 rounds over 13 yrs (0.5/yr) · Last round Conventional Debt (Apr 2026)
Product: 6 distinct product lines · Company stage: Series D
Innovation: 243 patents (top 5% of patent-holders) · 127 filings since 2022 vs 106 in 2017-21 · 6 product lines
Audience (LinkedIn): 16k LinkedIn followers · 76 engagements/post (1.8× cohort median)
Activity (LinkedIn): 1 awards announced in 12 mo
Funding rounds
  • Apr 2026Conventional Debt$50M
  • Oct 2025Series D$50M
  • Dec 2024Series D$50M
  • May 2022Series D
Founders & team
Deanna HarshbargerCEOKate RosenbluthFounder and Co-President
Investors
Google Ventures, Novartis, Johnson & Johnson Innovation, Baird Capital, Lux Capital, Lightstone Ventures
Tech stack
AccessibeAmplitudeApple Icloud MailCdnjsChoicesCloudflare
#2
Series C · San Francisco, California · founded 2010 · 251 employees
$129.3Mraised

CBT therapy for insomnia patients. Its flagship product Sleepio is a digital sleep improvement program, clinically proven to help users overcome poor sleep. Its virtual sleep expert "The Prof" teaches users proven Cognitive Behavioral Therapy (CBT) techniques, personalized to their problems and monitors their progress. Sleepio has been validated in the world’s first placebo-controlled RCT for a digital sleep intervention.

Fliar Intelligence Index™ 69how this company ranks against its industry peers
Tech
top 14%
Funding
top 23%
Moat
top 31%
News
top 36%
Market
top 37%
Talent
top 38%
Tech: 62 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 · Devops: Nginx, Varnish
Funding: Raised $129M across 5 rounds · 5 rounds over 12 yrs (0.4/yr) · Last round Series C (Feb 2026)
Moat: Editorial + unicorn rating 8/10 · Soonicorn · 10 curated direct competitors tracked
Audience (LinkedIn): 34k LinkedIn followers — 3.0% of this cohort's audience
Activity (LinkedIn): 1 partnerships (incl. Xealth) announced in 12 mo
Funding rounds
  • Feb 2026Series C$23.7M
  • Jan 2022Series C$75M
  • Jun 2020Series B$39M
  • Jul 2016Series B$12M
Founders & team
Colin EspieCo-FounderYael BermanCEO
Investors
Octopus Ventures, Kaiser Permanente Ventures, Index Ventures, JamJar Investments, Samsung NEXT, 5Y Capital
Tech stack
Amazon CloudfrontAmazon S3Amazon SesAmazon Web ServicesApolloApple Icloud Mail
#3
Series D · Los Altos Hills, California · founded 2021 · 52 employees
$104Mraised

Provider of a virtual care platform focused on female midlife health

Fliar Intelligence Index™ 80how this company ranks against its industry peers
Funding
top 14%
Growth
top 15%
News
top 20%
Tech
top 26%
Product
top 33%
Market
top 39%
Funding: Raised $104M across 6 rounds · 6 rounds over 4 yrs (1.5/yr) · Last round Series D (Feb 2026)
Growth: Web rank 500,000 → 50,000 YoY · Fresh capital in last 24 mo
News: 8 BI events in 12 mo (of 18 tracked, 2 types) · +300% YoY · 6 high-value events (IPO/M&A/funding/contracts) in 12 mo
Audience (LinkedIn): 87k LinkedIn followers — 7.8% of this cohort's audience
Funding rounds
  • Feb 2026Series D$100M
  • Oct 2025Series C$50M
  • Sep 2024Series B$5M
  • Apr 2024Series B$60M
Founders & team
Joanna StroberFounder
Investors
Felicis Ventures, SemperVirens, Emerson Collective, Icon Ventures, Operator Collective, Muse Capital
Tech stack
Amazon CloudfrontAmazon Web ServicesApple PayCart FunctionalityCloudflareCore-Js
#4
Series B · San Francisco, California · founded 2020 · 30 employees
$37Mraised

Provider of a wearable device for blood glucose pattern monitoring. The company has developed an app-based platform that recommends meals and exercises for users based on the glucose pattern detected through the connected device. The app provides real-time glucose monitoring and glucose spike levels for different foods. Based on this, personalized fitness and nutrition plan can be developed.

Fliar Intelligence Index™ 42how this company ranks against its industry peers
Tech
top 20%
Funding
top 25%
Moat
top 39%
Customers
top 44%
Product
top 46%
Talent
bottom 49%
Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services · Devops: Envoy
Funding: Raised $37.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) · Last round Series B (May 2026)
Moat: Editorial + unicorn rating 7/10 · 9 curated direct competitors tracked
Audience (LinkedIn): 9k LinkedIn followers
Funding rounds
  • Oct 2023Series B$20M
  • Nov 2021Series A$13M
  • Jan 2021Seed$4M
Founders & team
Sharam Fouladgar-MercerCo-Founder & CEO
Investors
Cheyenne Ventures, Google Ventures, Dexcom Ventures, Samsung NEXT, Courtside Ventures, 1984 Ventures
Tech stack
AddshoppersAmazon CloudfrontAmazon Web ServicesCloudflareCloudflare Bot ManagementCore-Js
#5
Series B · Encinitas, California · founded 2021 · 35 employees
$29.8Mraised

Provider of whole-body approach to healthcare delivering multiple services. The company's services include personalized care plans, prescription medication, at-home lab tests, virtual medical care, devices & supplies.

Fliar Intelligence Index™ 55how this company ranks against its industry peers
Funding
top 26%
Talent
top 28%
Growth
top 35%
Tech
top 38%
Product
top 46%
Moat
top 48%
Funding: Raised $29.8M across 2 rounds · 2 rounds over 4 yrs (0.5/yr) · Last round Series B (Mar 2026)
Talent: 4 named leaders on record · 4 C-suite/founder profiles curated
Growth: Fresh capital in last 24 mo
Audience (LinkedIn): 13k LinkedIn followers
Funding rounds
  • Mar 2026Series B$26M
  • Feb 2024Series A$9.5M
  • Apr 2022Series A
  • 2021Seed
Founders & team
Paul GeevargheseCo-Founder & COOBernhard SchandlCo-Founder & CTOAnton KittelbergerCo-Founder & Co-CEO
Investors
Cigna Ventures, 7wire Ventures, Define Ventures, Bayer, Founders Fund, Speedinvest
Tech stack
Amazon CloudfrontAmazon S3Amazon Web ServicesApple Icloud MailCloudflareCloudflare Bot Management
#6
Series D · Oakland, California · founded 2012 · 95 employees
$167Mraised

Eko offers an AI-based platform for remote monitoring of cardiac health. The solution offered by the company collects real-time patient data and analyses it to generate a report for doctors. The report generated aids in providing proper treatment to patients. The company has also developed products like Duo and Core stethoscopes for heart disease monitoring.

Fliar Intelligence Index™ 72how this company ranks against its industry peers
Funding
top 16%
Customers
top 22%
Tech
top 25%
Product
top 30%
Moat
top 31%
Talent
top 43%
Funding: Raised $167M across 16 rounds · 16 rounds over 11 yrs (1.5/yr) · Last round Grant (prize money) (Apr 2025)
Customers: Play-Store rating 4.81★ across 4,901 ratings (2 apps) · Review volume +17% in 6 mo
Tech: 61 technologies across 5/8 capability areas · Cloud: Amazon Web Services, Cloudflare · Devops: Envoy
Audience (LinkedIn): 20k LinkedIn followers
Activity (LinkedIn): 1 product launches · 1 partnerships (incl. Wayne General Hospital) announced in 12 mo
Funding rounds
  • Apr 2025Grant (prize money)$238.5K
  • Jun 2024Series D$41M
  • Sep 2022Grant (prize money)$2.3M
  • Sep 2022Grant (prize money)$2.7M
Founders & team
Jason BelletCo-FounderTyler CrouchCo-Founder
Investors
FOUNDER.org, StartX, 10x Group, Artis Ventures, Highland Capital Partners, NTTVC
Tech stack
Adobe Audience ManagerAlpine.JsAmazon Web ServicesApple Icloud MailApple PayCart Functionality
#7
Seed · Stanford, California · founded 2022 · 52 employees
$9.3Mraised

Provider of an app for women to manage gestational diabetes. The features of the app inlcude syncing glucose meters and automatically pulling in glucose levels. It uses AI to help identify food triggers for high blood glucose levels.

Fliar Intelligence Index™ 50how this company ranks against its industry peers
Growth
top 32%
Funding
top 36%
Talent
top 38%
Tech
top 46%
Customers
bottom 48%
Product
bottom 40%
Growth: Headcount 36 → 52 (+44%) across vintages · Fresh capital in last 24 mo
Funding: Raised $9.3M across 3 rounds · 3 rounds over 1 yrs (3.0/yr) · Last round Seed (Mar 2026)
Talent: 2 named leaders on record · 2 C-suite/founder profiles curated
Audience (LinkedIn): 4k LinkedIn followers
Funding rounds
  • Mar 2026Seed$5.9M
  • Mar 2026Grant (prize money)$3.3M
  • Seed$125K
Founders & team
Orlando LiCo-Founder & CTOMika EddyCo-Founder & CEO
Investors
Y Combinator, Acumen America, Capital F, Coyote Ventures, Wisdom Ventures, NIH
Tech stack
AngularCart FunctionalityCore-JsDatadogGoogle AnalyticsGoogle Tag Manager
#8
Series C · San Diego, California · founded 2012 · 91 employees
$175.1Mraised

Provider of a wearable biosensor platform for diabetes monitoring. It offers a wireless microsensor that enables users to understand their metabolism and blood glucose levels in real-time.

Fliar Intelligence Index™ 67how this company ranks against its industry peers
Innovation
top 13%
Funding
top 17%
Patents
top 17%
Moat
top 26%
Talent
top 38%
Growth
top 45%
Innovation: 189 patents (top 11% of patent-holders) · 161 filings since 2022 vs 28 in 2017-21 · Deep-tech classification: Tech Hardware
Funding: Raised $175M across 15 rounds · 15 rounds over 12 yrs (1.2/yr) · Last round Series C (Mar 2025)
Patents: 189 patents matched (strict assignee match) · 161 filings since 2022 vs 28 in 2017-21 · Latest publication 2026
Funding rounds
  • Mar 2025Series C$100M
  • Dec 2023Series B$59.1M
  • Nov 2021Series B$100M
  • Sep 2021Grant (prize money)$1.9M
Founders & team
Jared TangneyCo-FounderRichard YangCEO
Investors
M Ventures, Hikma Ventures, Three Leaf Ventures, LifeSci Venture Partners, GSVP, Alpha Wave Global
Tech stack
Google AnalyticsGreenhouseJqueryJsdelivrLottiefilesOpen Graph
#9
Series D · Walnut Creek, California · founded 2012 · 110 employees
$25Mraised

SafeinHome offers a home monitoring system for the elderly. The system uses small discreet sensors placed in the house to monitor activity and send alerts in case anything is abnormal. The system can monitor sleep, movement around the house and send alerts to family caregivers smartphones.

Fliar Intelligence Index™ 57how this company ranks against its industry peers
Growth
top 21%
Funding
top 30%
Product
top 36%
Moat
top 42%
Tech
top 50%
Talent
bottom 49%
Growth: Headcount 53 → 110 (+108%) across vintages · Fresh capital in last 24 mo
Funding: Raised $25.0M across 1 rounds · 1 rounds over 9 yrs (0.1/yr) · Last round Series D (Dec 2025)
Product: 1 published app (300 installs) · Company stage: Series D
Audience (LinkedIn): 2k LinkedIn followers
Funding rounds
  • Dec 2025Series D$25M
  • Dec 2017Grant (prize money)
Founders & team
Ken TraversoChief Executive Officer
Investors
MassChallenge, SEMCAP, Partners For Growth
Tech stack
AccessibeAddtoanyBootstrapCdnjsCloudflareCloudflare Browser Insights
#10
Series G · Campbell, California · founded 2011 · 184 employees
$139.9Mraised

Developer of biosensor patch for body vitals monitoring. Its biosensor patch measures multiple parameters including heart rate, heart rate variability, respiratory rate, single-lead ECG, skin temperature, body posture, fall detection, and activities like step counting. It has applications for use in hospitals, homes, research facilities, HCPs, and care facilities.

Fliar Intelligence Index™ 64how this company ranks against its industry peers
Product
top 18%
Funding
top 21%
Moat
top 26%
Patents
top 32%
Talent
top 34%
Innovation
top 36%
Product: 6 distinct product lines · Company stage: Series G
Funding: Raised $140M across 8 rounds · 8 rounds over 15 yrs (0.5/yr) · Last round Series G (Feb 2025)
Moat: Editorial + unicorn rating 8/10 · IP moat: 239 patents · Soonicorn
Audience (LinkedIn): 10k LinkedIn followers
Funding rounds
  • Feb 2025Conventional Debt
  • Feb 2025Series G$100M
  • Jul 2023Series F$30M
  • Sep 2022Series D
Founders & team
Nersi NazariFounderPeter Van HaurChief Executive Officer
Investors
Oxford Finance, MVM, Baxter, HCA, Revelation Partners, Pacific General Ventures
Tech stack
Amazon Web ServicesAnimate.CssCore-JsFlywheelFont AwesomeGoogle Analytics
#11
Series F · Palo Alto, California · founded 2010 · 121 employees
$201Mraised

Glooko is a diabetes management solution for patients, health systems, and payer groups. Glooko’s products enable clinicians to remotely access their patients’ blood glucose readings and other related data, and optimize their insulin therapy. The company’s System allows people with diabetes to download their glucose readings to their mobile devices. According to the company, their population management web app offers diabetes-centric analytics and supplies insightful reports, graphs and pattern-triggered notifications to patients, health systems and payers. Partners include Abbott, Roche, LifeScan, Medtronic, Omnipod, Bayer, Nipro, and Arkray among others. Glooko and Diasend got merged in September 2016 and the combined companies operate under the Glooko moniker.

Fliar Intelligence Index™ 53how this company ranks against its industry peers
Funding
top 18%
Product
top 27%
Tech
top 29%
Moat
top 35%
Growth
top 43%
Market
top 46%
Funding: Raised $201M across 8 rounds · 8 rounds over 15 yrs (0.5/yr) · Last round Series F (Oct 2024)
Product: 2 published apps (452k installs) · Company stage: Series F
Tech: 58 technologies across 5/8 capability areas · Cloud: Amazon Alb, Amazon Cloudfront · Devops: Envoy
Audience (LinkedIn): 14k LinkedIn followers
Activity (LinkedIn): 2 product launches announced in 12 mo
Funding rounds
  • Oct 2024Series F$100M
  • Mar 2021Series D$30M
  • Jun 2017Series C$35M
  • Sep 2016Series B$8M
Founders & team
Mike AlvarezCEO
Investors
Health Catalyst Capital, Canaan, New Nordic, Insulet, Mayo Clinic, Georgian
Tech stack
Amazon AlbAmazon CloudfrontAmazon S3Amazon SesAmazon Web ServicesApple Icloud Mail
#12
Series A · Mountain View, California · founded 2020 · 20 employees
$12.7Mraised

Developer of wireless earbuds that monitor brain activity and enhance sleep. The earbuds use sensors to capture brain rhythms and track body movement. They measure sleep metrics and provide an intelligent relaxation experience with science-backed audio. The product automatically pauses audio when sensors detect sleep.

Fliar Intelligence Index™ 48how this company ranks against its industry peers
Innovation
top 30%
Patents
top 30%
Funding
top 33%
Tech
top 36%
News
top 46%
Moat
top 47%
Innovation: 38 patents (top 37% of patent-holders) · 33 filings since 2022 vs 5 in 2017-21 · Deep-tech classification: Tech Hardware
Patents: 38 patents matched (strict assignee match) · 33 filings since 2022 vs 5 in 2017-21 · Latest publication 2026
Funding: Raised $12.7M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) · Last round Series A (Nov 2025)
Audience (LinkedIn): 7k LinkedIn followers
Hiring (LinkedIn): 1 hiring post in 12 mo (public) · hiring: Digital Marketing Manager
Activity (LinkedIn): 3 product launches · 1 awards announced in 12 mo
Funding rounds
  • Nov 2025Series A$16M
  • Apr 2024Series A$16.3M
  • Nov 2023Seed$3M
Founders & team
Jonathan BerentCEO & Founder
Investors
Angelini Ventures, Ascension Ventures, Satori Capital, Corundum Neuroscience, Particular Ventures
Tech stack
Apple Icloud MailApple PayCart FunctionalityCloudflareCloudflare Bot ManagementContentsquare

Funding & investor landscape

$10.1Btotal disclosed funding
362companies funded
1,008disclosed rounds
1rounds last 90 days
Most active investors
HHS39 rounds
Y Combinator32 rounds
Techstars19 rounds
Berkeley SkyDeck15 rounds
National Science Foundation14 rounds
Plug and Play Tech Center13 rounds
UCSF Rosenman Institute13 rounds
Khosla Ventures12 rounds
Rock Health12 rounds
Gaingels11 rounds

Notable founders

Deanna Harshbarger
CEO · Cala Health
Kate Rosenbluth
Founder and Co-President · Cala Health
Colin Espie
Co-Founder · BigHealth
Yael Berman
CEO · BigHealth
Joanna Strober
Founder · Join Midi
Sharam Fouladgar-Mercer
Co-Founder & CEO · Signos
Paul Geevarghese
Co-Founder & COO · 9amHealth
Bernhard Schandl
Co-Founder & CTO · 9amHealth
Jason Bellet
Co-Founder · Eko
Tyler Crouch
Co-Founder · Eko
Orlando Li
Co-Founder & CTO · Malama Health
Mika Eddy
Co-Founder & CEO · Malama Health
Prism market signals · United States · country-scoped Prism corpus, 1,253,315 docs

Market landscape — 10 sub-themes by coverage

Share of Disease Self Management coverage by sub-theme.

Regulatory-risk over time falling

Funding & growth over time

funding flat · growth flat

RESEARCH IN CALIFORNIA · Health & Bio

How research on Digital Health in California is moving

A read on the academic research around Digital Health in California — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 626 papers.

UCSF, UCLA, and UC San Diego lead California's digital-health research—dominated by mobile health, telehealth, and digital mental health—with a cautiously contested tone reflecting more concerns than breakthroughs.

626 papers · stance +0.20 · 16% breakthrough · 45% concern
breakthrough · advancement · concern
top institutions
  • University of California, San Francisco154
  • University of California, Los Angeles80
  • University of California San Diego75
  • University of California, Irvine73
  • University of Southern California62
leading researchers
Gregory A. Aarons · Khoong, Elaine · Stephen M. Schueller · Aaron R. Lyon · Julia Adler‐Milstein · Borsika A. Rabin
prism intelligence · tone & topics
87% positive · 9% critical tone
HealthcareBusinessMental HealthPublic HealthEducationGovernment
Breakthroughs82 · 13%
▼ 15%→14% share
▼0.9× share momentum0 median citations87% since 2021mostly methods-led
Wearable computer research is surging — papers rose from 2 to 14, driving 15% of breakthrough activity.
rising sub-themes (early→recent)
  • Wearable computer2→14
  • Health care1→13
  • Health informatics4→9
  • Telemedicine1→5
  • Remote patient monitoring4→7
Newly emergingWearable technology 0→7 · Informatics 0→7 · Workflow 0→4
Landmark IoT-Based Remote Pain Monitoring System: From Device to Cloud Platform · 181 cites
Advancements210 · 34%
▲ 33%→34% share
▲1.0× share momentum0 median citations85% since 2021mostly empirical
mHealth psychological intervention research is intensifying — combined topics scaled from single digits to 25 and 23 papers respectively.
rising sub-themes (early→recent)
  • Health care4→58
  • Health informatics10→38
  • mHealth2→25
  • Psychological intervention1→23
  • Public health3→20
Newly emergingIntervention (counseling) 0→14 · Health literacy 0→13 · Set (abstract data type) 0→11
Landmark Implementing shared decision-making: consider all the consequences · 432 cites
Concerns237 · 38%
▼ 39%→36% share
▼0.9× share momentum3 median citations78% since 2021mostly empirical
Health informatics safety concerns are intensifying — papers grew from 11 to 53, dominating 36% of concerns share.
rising sub-themes (early→recent)
  • Health care4→47
  • Health informatics11→53
  • Public health3→34
  • Health administration9→32
  • Psychological intervention4→25
Newly emergingQualitative research 0→13 · MEDLINE 0→11 · Intervention (counseling) 0→10
Landmark Developing and Evaluating Digital Interventions to Promote Behavior Change in Health and Health Care: Recommendations Re · 952 cites

Common questions

How many Disease Self Management companies are there in California, United States?
Radar tracks 936 indexable Disease Self Management companies headquartered in California, United States that meet our profile-completeness bar.
What is the total funding raised by Disease Self Management companies in California, United States?
The Disease Self Management companies in California, United States on this list have raised a combined $10.1B in disclosed equity funding across 362 funded companies.
Which is the highest-funded Disease Self Management company in California, United States?
Jawbone is the highest-funded Disease Self Management company in California, United States, with $877M in disclosed equity funding.
How many Disease Self Management companies in California, United States are funded?
362 of the 936 Disease Self Management companies in California, United States on this list have disclosed at least one equity funding round.
How many Disease Self Management unicorns are there in California, United States?
7 Disease Self Management companies in California, United States on this list are valued at $1B or more.
Who are the top investors in California, United States Disease Self Management companies?
The most active investors in California, United States Disease Self Management companies on this list include HHS, Y Combinator, Techstars, Berkeley SkyDeck, National Science Foundation.
Riya SenguptaFinancials

Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.

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