2899 indexable Disease Self Management companies headquartered in United States, ranked by total equity funding and recent funding momentum. Combined disclosed equity funding of $18.5B across 1025 funded companies, including 9 unicorns.
| # | Company | Funding | Valuation | Stage | Latest round | Employees | Founded | Momentum |
|---|---|---|---|---|---|---|---|---|
| 1 |
Cala Health
Developer of a wearable non-invasive neuromodulation device |
$157.1M | — | Series D | Conventional Debt Apr 2026 | 50 | 2013 | ↑ Active |
| 2 |
BigHealth
CBT therapy for insomnia patients |
$129.3M | — | Series C | Series C Feb 2026 | 251 | 2010 | ↑ Active |
| 3 |
Join Midi
Unicorn Provider of a virtual care platform focused on female midlife health |
$104M | — | Series D | Series D Feb 2026 | 52 | 2021 | ↑ Active |
| 4 |
Signos
Provider of a wearable device for blood glucose pattern monitoring |
$37M | — | Series B | Series B May 2026 | 30 | 2020 | ↑ Active |
| 5 |
MedRhythms
Provider of wearable devices to combat neurological injuries and recover walking functions |
$57.1M | — | Series B | Series B Feb 2026 | 41 | 2013 | ↑ Active |
| 6 |
Nanit
Provider of smart baby monitoring systems with sleep and breathing analysis |
$75M | — | Series D | Series D Dec 2025 | 111 | 2014 | ↑ Active |
| 7 |
Sword Health
Unicorn Provider of AI-powered digital physical therapy and pelvic health solutions |
$340M | $3B as of 2024 |
Series E | Series E Jun 2025 | 1 | 2015 | ↑ Active |
| 8 |
Lumia Health
Developer of wearable ear devices tracking blood flow to head |
$29.1M | — | Series B | Series B Mar 2026 | — | 2020 | ↑ Active |
| 9 |
BioIntelliSense
Developer of medical-grade wearable devices and data services for patient monitoring |
$82M | — | Series C | Series C Dec 2025 | 26 | 2018 | ↑ Active |
| 10 |
9amHealth
Provider of whole-body approach to healthcare delivering multiple services |
$29.8M | — | Series B | Series B Mar 2026 | 35 | 2021 | ↑ Active |
| 11 |
Huxley Medical
Provider of wearable devices to monitor body chemistry |
$12.6M | — | Series A | Series A Apr 2026 | 16 | 2019 | ↑ Active |
| 12 |
Axion
Developer of medical device depression treatment support program for patients |
$62M | — | Series B | Series B Dec 2025 | — | 2021 | ↑ Active |
| 13 |
Jana Care
Provider of mobile-based healthcare diagnostics for diabetes prevention |
$17.7M | — | Series C | Series C Mar 2026 | 60 | 2011 | ↑ Active |
| 14 |
Ubie
Developer of an AI-powered system providing symptom check and medical information |
$110.5M | — | Series C | Series C Jun 2025 | 250 | 2017 | ↑ Active |
| 15 |
Patientory
Provider of a digital health passport wallet and related healthcare services |
$6.9M | — | Series A | Series A Apr 2026 | 8 | 2015 | ↑ Active |
| 16 |
Neuros Medical
Neurostimulation therapy for chronic neuropathic pain |
$89.2M | — | Series D | Series D Jul 2025 | 28 | 2008 | ↑ Active |
| 17 |
Eko
Provider of AI-based remote patient monitoring platform for cardiac health |
$167M | — | Series D | Grant (prize money) Apr 2025 | 95 | 2012 | ↑ Active |
| 18 |
Malama Health
Provider of an app for women to manage gestational diabetes |
$9.3M | — | Seed | Seed Mar 2026 | 52 | 2022 | ↑ Active |
| 19 |
Biolinq
Provider of a wearable biosensor platform for diabetes monitoring |
$175.1M | — | Series C | Series C Mar 2025 | 91 | 2012 | ↑ Active |
| 20 |
LifeLens
Developer of wireless ECG monitor for personal health monitoring use |
$24.6M | — | Series B | Series B Nov 2025 | 45 | 2014 | ↑ Active |
| 21 |
SafeinHome
A home monitoring system for the elderly |
$25M | — | Series D | Series D Dec 2025 | 110 | 2012 | ↑ Active |
| 22 |
Inito
Provider of test devices to track fertility hormones at home |
$15M | $1.5M as of 2023 |
Series B | Series B Dec 2025 | 175 | 2012 | ↑ Active |
| 23 |
LibAirty
Provider of airway clearance system synchronizing controlled breathing with chest compressions |
$9.3M | — | Series A | Series A Feb 2026 | — | 2016 | ↑ Active |
| 24 |
SOBR Safe
Manufacturer of medical devices |
$12.7M | — | Public | Post IPO Dec 2025 | 15 | 2007 | ↑ Active |
| 25 |
Neopenda
Provider of wearable neonatal signs monitor |
$2.7M | — | Seed | Conventional Debt Apr 2026 | 14 | 2015 | ↑ Active |
| 26 |
AngelEye Health
Provider of video, data, and analysis solutions for pediatric patient care |
$12.2M | — | Series C | Series C Dec 2025 | 48 | 2013 | ↑ Active |
| 27 |
Vital Connect
Developer of biosensor patch for body vitals monitoring |
$139.9M | — | Series G | Series G Feb 2025 | 184 | 2011 | ↑ Active |
| 28 |
Cloud
Provider of cloud-based remote cardiology vital signs monitoring devices and platforms |
$3.1M | — | Public | Post IPO Mar 2026 | 55 | 2014 | ↑ Active |
| 29 |
K Health
Unicorn AI-based platform providing access to clinicians |
$438.5M | $900M as of 2024 |
Series F | Series F Jul 2024 | 19 | 2016 | ↑ Active |
| 30 |
Somatix
Provider of an AI-based remote health monitoring tool |
$17.3M | — | Acquired | Series A Sep 2025 | 27 | 2015 | ↑ Active |
| 31 |
NightWare
Developer of a prescription digital therapeutic system for nightmare disorder |
$3.5M | — | Seed | Seed Feb 2026 | 16 | 2015 | ↑ Active |
| 32 |
IBS
Developer of fingerprint drug testing and sweat drug monitoring solutions |
$10M | — | Public | Post IPO Dec 2025 | 26 | 2016 | ↑ Active |
| 33 |
Glooko
Glucose meter and mobile app for diabetes management |
$201M | — | Series F | Series F Oct 2024 | 121 | 2010 | ↑ Active |
| 34 |
NextSense
Developer of wireless earbuds that monitor brain activity and enhance sleep |
$12.7M | — | Series A | Series A Nov 2025 | 20 | 2020 | ↑ Active |
| 35 |
Youth Health Tech
Platform offering health screening solutions |
$4.5M | — | Series A | Series A Feb 2026 | — | 2023 | ↑ Active |
| 36 |
Avertix
Provider of an implantable heart attack warning system |
$13.8M | — | Series B | Series B Sep 2025 | 31 | 2001 | ↑ Active |
| 37 |
Adaptyx Biosciences
Platform offering microneedle sensor patch |
$14.2M | — | Seed | Seed Oct 2025 | — | 2022 | ↑ Active |
| 38 |
Spark Biomedical
Developer of wearable neurostimulation technology for drug-free opioid withdrawal treatment |
$16.2M | — | Series A | Grant (prize money) Aug 2025 | 18 | 2018 | ↑ Active |
| 39 |
AventuSoft
Cloud connected wearable to detect heart related abnormalities |
$13.7M | — | Funding Raised | Grant (prize money) Sep 2025 | 4 | 2013 | ↑ Active |
| 40 |
K4Connect
Integrated technology solutions enhancing senior living community experiences and operational efficiency |
$51.3M | — | Series C | Series C Mar 2025 | 48 | 2013 | ↑ Active |
| 41 |
Sibel Health
Developer of wireless medical monitoring devices for clinical and remote use |
$50M | — | Series C | Series C Mar 2025 | 47 | 2018 | ↑ Active |
| 42 |
BrainCo
Provider of a prosthetic hand and EEG headband for brain signal |
$5.5M | — | Series A | Series A Jan 2026 | 40 | 2015 | ↑ Active |
| 43 |
SafelyYou
Provider of AI-based solutions for senior care and fall management |
$59.5M | — | Series C | Series C Jan 2025 | 85 | 2014 | ↑ Active |
| 44 |
CoachCare
Provider of remote patient monitoring and virtual health support services |
$48.2M | — | Series C | Series C Feb 2025 | 45 | 2013 | ↑ Active |
| 45 |
PhotoPharmics
Developer of non-invasive phototherapy for Parkinson's disease |
$29.7M | — | Series B | Series B Apr 2025 | 7 | 2011 | ↑ Active |
| 46 |
Redi
Mobile-based application of medication adherence management |
$17.7M | — | Series B | Series B Aug 2025 | 20 | 2021 | ↑ Active |
| 47 |
Wellinks
Provider of virtual pulmonary rehabilitation and personalized chronic obstructive pulmonary disease management |
$26.1M | — | Series A | Series A May 2025 | 41 | 2013 | ↑ Active |
| 48 |
BrainHQ
Online brain training platform for cognitive improvement and brain health |
$11.8M | — | Series A | Grant (prize money) Jul 2025 | 31 | 2002 | ↑ Active |
| 49 |
VerAvanti
Innovating intravascular imaging with advanced single-use endoscopes for enhanced patient care |
$5.5M | — | Series B | Series B Oct 2025 | 13 | 2012 | ↑ Active |
| 50 |
DUSQ
Developer of sleep science studying recovery regulation under modern conditions |
$2.6M | — | Seed | Seed Feb 2026 | — | 2024 | ↑ Active |
Developer of a wearable non-invasive neuromodulation device. The company has developed a neuromodulation device that aims to provide relief of hand tremors in adults with essential tremors. It combines a watch-like device with an implantable sensor that externally stimulates peripheral nerves to reduce the same. The company has also developed a portable medical device with sensors to monitor the physical movement of
CBT therapy for insomnia patients. Its flagship product Sleepio is a digital sleep improvement program, clinically proven to help users overcome poor sleep. Its virtual sleep expert "The Prof" teaches users proven Cognitive Behavioral Therapy (CBT) techniques, personalized to their problems and monitors their progress. Sleepio has been validated in the world’s first placebo-controlled RCT for a digital sleep interv
Provider of a virtual care platform focused on female midlife health
Provider of a wearable device for blood glucose pattern monitoring. The company has developed an app-based platform that recommends meals and exercises for users based on the glucose pattern detected through the connected device. The app provides real-time glucose monitoring and glucose spike levels for different foods. Based on this, personalized fitness and nutrition plan can be developed.
Provider of wearable devices to combat neurological injuries and recover walking functions. The company has developed inertial measurement unit (IMU) sensors to measure gait parameters and run proprietary algorithms on them to make changes to the music accordingly. It uses artificial intelligence to personalize and improve the algorithm over time, as well as make predictive insights about the user population.
Provider of smart baby monitoring systems with sleep and breathing analysis. The systems offer real-time safety notifications, video history, and personalized sleep coaching. Features include breathing motion monitoring without sensors and advanced sleep insights. The company provides a range of compatible accessories, including breathing wear and display screens. It also offers membership plans for expanded data and
Provider of AI-powered digital physical therapy and pelvic health solutions. It offers personalized therapy programs combining artificial intelligence with human clinical expertise. These programs address muscle and joint pain, pelvic health conditions, and movement health issues. The company also provides on-demand access to clinical pain specialists and educational resources. Its solutions are designed to improve p
Developer of wearable ear devices tracking blood flow to head. These devices monitor physiological metrics to assist individuals in understanding how daily activities and physical positioning influence blood circulation. The hardware integrates with mobile software to record and analyze data regarding heart rate and blood flow patterns. Users can tag specific events or behaviors to identify factors that affect their
Developer of medical-grade wearable devices and data services for patient monitoring. it provides BioButton a rechargeable, multi-parameter wearable that captures vital signssuch as heart rate, respiratory rate, and skin temperature. It is integrated with data platforms BioCloud that provides advanced analytics and algorithmic notifications to support actionable triage and workflow efficiency and BioDashboard that En
Provider of whole-body approach to healthcare delivering multiple services. The company's services include personalized care plans, prescription medication, at-home lab tests, virtual medical care, devices & supplies.
Provider of wearable devices to monitor body chemistry. It is offering an ultrathin biosensor patch to monitor and communicate various details of body chemistry and composition.
Developer of medical device depression treatment support program for patients. The program aims to provide support for individuals undergoing depression treatment. The company focuses on research, development, and sales in the medical device field. It is actively seeking partners for further research, development, and sales efforts.
Rankings are computed by Radar (Fliar BI) from the Radar company master and are updated periodically. Funding and momentum scores use disclosed equity-funding data only. Figures may lag private rounds. Last updated 2026-06-16.