Radar · Healthcare in Birmingham
Best Healthcare Companies in Birmingham, United States
The 106 best Healthcare companies in Birmingham, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Upstream.
By Rohit KhannaTrends & Stories
106companies tracked
$991.9Mdisclosed funding
0unicorns
16have raised
Ranked: Best Healthcare companies in Birmingham
| # | Company | Disclosed funding | Last round | Stage | Employees | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Upstream Chain of outpatient physical therapy clinics | $745M | 79 mo ago | Seed | 7,400 | 2004 | WordPressMySQLPHP+20 | — | — |
| 2 | HighFive Healthcare Provider of dental care consulting services | $102M | 33 mo ago | Series C | 62 | 2018 | Webflow EcommerceWebflowApple iCloud Mail+13 | — | — |
| 3 | TRMC Chain of multispecialty hospital | $50M | 64 mo ago | Funding Raised | 30 | 2019 | — | — | — |
| 4 | ContinuumRx Specialty infusion services | $20M | 131 mo ago | Series B | 66 | 2001 | WordPress Block EditorwpBakeryWordPress+25 | — | — |
| 5 | Uabmedicine Chain of multispecialty hospitals | $16M | 212 mo ago | Funding Raised | 497 | 1996 | WordPress Block EditorWordPressMySQL+22 | — | 1 partnership · 1 expansion |
| 6 | Acclinate Provider of clinical trial services to biopharma sector 9Funding top 38%News top 43%Moat bottom 44%Patents bottom 37% All 7 signals ▾Fundingtop 38% Newstop 43% Moatbottom 44% Patentsbottom 37% Globalbottom 33% Marketbottom 30% Innovationbottom 23% Funding: Raised $12.0M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) News: 2 BI events in 12 mo (of 6 tracked, 4 types) · Top themes: Announcements rank vs industry peers · Fliar Intelligence Index 9/100 | $12M | 4 mo ago | Series A | 33 | 2020 | — | 2 patents Automated patient eligibility assessment and recruitment for clinical trials | — |
| 7 | Christ Health Center The Christ Health Center offers primary care, dentistry, counseling, and medication therapy management… | $12M | 12 mo ago | Funding Raised | 66 | 2009 | WordPressApple iCloud MailMicrosoft 365+20 | — | — |
| 8 | Yuva Biosciences Developer of cosmeceuticals and pharmaceuticals | $9M | 3 mo ago | Seed | 5 | 2018 | — | — | 1 partnership |
| 9 | Alveolus Bio Provider of biotherapeutics services for lung diseases treatment | $8M | 10 mo ago | Seed | 7 | 2021 | WordPressMySQLPHP+13 | — | — |
| 10 | Practice Partners in Healthcare Standalone ambulatory surgery clinic | $7M | 228 mo ago | Series A | 14 | 2005 | — | — | — |
| 11 | Hygia Health Services Single-use medical device reprocessor | $3M | 175 mo ago | Acquired | — | 1999 | — | — | — |
| 12 | Rampart Manufacturer of medical devices for multiple therapeutic areas 53Patents top 29%Innovation top 31%Funding top 44%Moat top 45% All 8 signals ▾Patentstop 29% Innovationtop 31% Fundingtop 44% Moattop 45% Techbottom 43% Marketbottom 42% Globalbottom 35% Newsbottom 21% Patents: 24 patents matched (strict assignee match) · 20 filings since 2022 vs 2 in 2017-21 Innovation: 24 patents (top 47% of patent-holders) · 20 filings since 2022 vs 2 in 2017-21 rank vs industry peers · Fliar Intelligence Index 53/100 | $3M | 13 mo ago | Series B | 19 | 2014 | Squarespace CommerceSquarespaceApple iCloud Mail+18 | 24 patents Radiation shielding systems for medical imaging tables and related protective equipment | — |
| 13 | Children’s of Alabama Chain of children hospitals | $2M | 12 mo ago | Funding Raised | 5,095 5,095 → 3,537 (-31%) | 1911 | Cart FunctionalityApple iCloud MailFroala Editor+36 | — | 1 job opening · 1 award |
| 14 | Personal Best Standalone wellness centre | $431K | 51 mo ago | Early Stage | 16 | 1982 | Windows ServerMicrosoft ASP.NETIIS+12 | — | — |
| 15 | St. Vincent's Health System Network of multispeciality hospitals | $368K | 180 mo ago | Early Stage | 1,084 | 1898 | — | — | 2 expansions · 1 award |
| 16 | NuTech Distributor of amniotic stem-cell-based products 53Patents top 16%Product top 18%Innovation top 21%Moat top 41% All 8 signals ▾Patentstop 16% Producttop 18% Innovationtop 21% Moattop 41% Talentbottom 45% Techbottom 42% Globalbottom 40% Fundingbottom 23% Patents: 664 patents matched (strict assignee match) · 257 filings since 2022 vs 266 in 2017-21 Product: 6 distinct product lines rank vs industry peers · Fliar Intelligence Index 53/100 | $325K | 184 mo ago | Early Stage | — | 1994 | — | 664 patents Patents concentrated in chemistry & materials | — |
| 17 | One Nineteen GI ASC Standalone ambulatory surgery clinics | $175K | 27 mo ago | Seed | — | — | — | — | — |
| 18 | Creek Leaf Wellness Standalone wellness center | $100K | 44 mo ago | Seed | — | 2022 | — | — | — |
Top 12 Healthcare companies in Birmingham
#1
Series A · Birmingham, Alabama · founded 2020 · 33 employees$12Mraised▾
Series A · Birmingham, Alabama · founded 2020 · 33 employees
Provider of clinical trial services to biopharma sector
Fliar Intelligence Index™ 9how this company ranks against its industry peers
Funding
top 38%News
top 43%Moat
bottom 44%Patents
bottom 37%Global
bottom 33%Market
bottom 30%Funding: Raised $12.0M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) · Last round Series A (Feb 2026)
News: 2 BI events in 12 mo (of 6 tracked, 4 types) · Top themes: Announcements
Moat: Editorial + unicorn rating 1/10 · IP moat: 2 patents · 9 curated direct competitors tracked
Audience (LinkedIn): 8k LinkedIn followers — 2.2% of this cohort's audience
Funding rounds
- Feb 2026Series A$3.5M
- May 2024Series A$7M
- Oct 2022Series A$4.9M
- Oct 2022Grant (prize money)—
Investors
Johnson & Johnson Innovation, Alabama Launchpad, Cencora, LabCorp, Latimer Ventures, Techstars
#2
Seed · Birmingham, Alabama · founded 2018 · 5 employees$8.6Mraised▾
Seed · Birmingham, Alabama · founded 2018 · 5 employees
Developer of cosmeceuticals and pharmaceuticals
LinkedIn Pulse recent public activity · Jul 2026
Audience: 695 LinkedIn followers
Activity: 2 partnerships · 1 awards (incl. Rerise) announced in 12 mo
Funding rounds
- Mar 2026Seed$1.1M
- Feb 2024Seed$7.5M
Founders & team
Investors
VentureSouth, Longevitytech.fund, Innovation Depot
#3
Seed · Birmingham, Alabama · founded 2021 · 7 employees$8.4Mraised▾
Seed · Birmingham, Alabama · founded 2021 · 7 employees
Developer of COPD drugs intended for the prevention and treatment of chronic lung diseases. The company's drugs offer therapeutics that specifically target lung diseases developed by an interdisciplinary team of physicians, researchers, and innovators collaborating at the intersection of respiratory medicine, microbiome science, and drug delivery modalities, enabling medical professionals to target microbiome-based pathways to alter the course of respiratory diseases among the patients.
Funding rounds
- Aug 2025Seed—
- Apr 2025Grant (prize money)$2.3M
- Feb 2025Grant (prize money)$2.3M
- Mar 2023Grant (prize money)$2.5M
Investors
HHS, Shilpa Medicare, Innovation Depot, Lumira Ventures
Tech stack
CloudflareCloudflare Bot ManagementDiviGodaddyGodaddy CoblocksGoogle Font Api
#4
Funding Raised · Birmingham, Alabama · founded 2009 · 66 employees$11.6Mraised▾
Funding Raised · Birmingham, Alabama · founded 2009 · 66 employees
The work we are doing at Christ Health Center goes well beyond treating the sick. We are committed to the physical, mental and spiritual health and well-being of each of our patients. More than simply seeing the sick made well, at Christ Health Center we strive to see the well made whole and to see each patient living life abundantly. Our patients have access to the very best in primary care, dental services and professional counseling as well as medication therapy management through our on-site pharmacy.
LinkedIn Pulse recent public activity · Jul 2026
Audience: 774 LinkedIn followers
Hiring: 1 hiring post in 12 mo (public)
Funding rounds
- May 2025Grant (prize money)$64.7K
- Mar 2025Grant (prize money)$704.6K
- Jan 2025Grant (prize money)$10.8M
Investors
HHS
Tech stack
Apple Icloud MailCloudflareCloudflare Bot ManagementCloudflare Browser InsightsConstant ContactElementor
#5
Funding Raised · Birmingham, Alabama · founded 1911 · 5095 employees$2.2Mraised▾
Funding Raised · Birmingham, Alabama · founded 1911 · 5095 employees
Chain of children hospitals
LinkedIn Pulse recent public activity · Jul 2026
Audience: 25k LinkedIn followers — 7.2% of this cohort's audience
Hiring: 1 hiring post in 12 mo (public) · hiring: Certified Registered Nurse Anesthetist
Activity: 1 awards announced in 12 mo
Funding rounds
- 2025Grant (prize money)$2.2M
Founders & team
Investors
HRSA, HHS
Tech stack
AngularjsApple Icloud MailAppnexusAxiosBabelBrightedge
#6
Series B · Birmingham, Alabama · founded 2014 · 19 employees$3.1Mraised▾
Series B · Birmingham, Alabama · founded 2014 · 19 employees
Manufacturer of medical devices for multiple therapeutic areas
Fliar Intelligence Index™ 53how this company ranks against its industry peers
Patents
top 29%Innovation
top 31%Funding
top 44%Moat
top 45%Tech
bottom 43%Market
bottom 42%Patents: 24 patents matched (strict assignee match) · 20 filings since 2022 vs 2 in 2017-21 · Latest publication 2026
Innovation: 24 patents (top 47% of patent-holders) · 20 filings since 2022 vs 2 in 2017-21
Funding: Raised $3.1M across 2 rounds · 2 rounds over 6 yrs (0.3/yr) · Last round Series B (Apr 2025)
Audience (LinkedIn): 7k LinkedIn followers
Funding rounds
- Apr 2025Series B$21.6M
- Sep 2020Series A$3.1M
Investors
Vensana Capital
#7
Series C · Birmingham, Alabama · founded 2018 · 62 employees$102.2Mraised▾
Series C · Birmingham, Alabama · founded 2018 · 62 employees
Provider of dental care consulting services
LinkedIn Pulse recent public activity · Jul 2026
Audience: 2k LinkedIn followers
Funding rounds
- Sep 2023Conventional Debt—
- Jun 2023Series C$100M
- Nov 2018Seed$2.2M
Founders & team
Investors
Comvest Partners, Krowten Capital, Jemison Investment Company, Norwest, Capital Alignment Partners
Tech stack
Apple Icloud MailCloudflareGoogle AnalyticsGoogle Font ApiGoogle Hosted LibrariesGoogle Tag Manager
#8
Seed · Birmingham, Alabama · founded 2004 · 7400 employees$745Mraised▾
Seed · Birmingham, Alabama · founded 2004 · 7400 employees
Chain of outpatient physical therapy clinics
LinkedIn Pulse recent public activity · Jul 2026
Audience: 12k LinkedIn followers — 3.6% of this cohort's audience
Funding rounds
- Nov 2019Conventional Debt$745M
- Dec 2015Seed—
Investors
Revelstoke Capital Partners, Yukon Partners, WP Global Partners, Churchill Asset Management, White Oak Enterprises, Maranon Capital
Tech stack
Amazon Web ServicesAmerican ExpressApple Icloud MailBootstrapCart FunctionalityCloudflare
#9
Funding Raised · Birmingham, Alabama · founded 2019 · 30 employees$50Mraised▾
Funding Raised · Birmingham, Alabama · founded 2019 · 30 employees
Chain of multispecialty hospital
Funding rounds
- Feb 2021Conventional Debt$50M
Investors
North Avenue Capital
#10
Funding Raised · Birmingham, Alabama · founded 1996 · 497 employees$15.9Mraised▾
Funding Raised · Birmingham, Alabama · founded 1996 · 497 employees
Chain of multispecialty hospitals
LinkedIn Pulse recent public activity · Jul 2026
Audience: 50k LinkedIn followers — 14.3% of this cohort's audience · 26 engagements/post (1.7× cohort median)
Activity: 1 partnerships · 1 expansions (incl. Junior Achievement of Alabama) announced in 12 mo
Funding rounds
- Sep 2008Grant (prize money)$25K
- Sep 2008Grant (prize money)$66.7K
- Sep 2008Grant (prize money)$317.9K
- Aug 2008Grant (prize money)$291.4K
Investors
HHS
Tech stack
Amazon CloudfrontAmazon Web ServicesBootstrapCore-JsDatadogDay.Js
#11
Series B · Birmingham, Alabama · founded 2001 · 66 employees$20.5Mraised▾
Series B · Birmingham, Alabama · founded 2001 · 66 employees
Specialty infusion services
Funding rounds
- Jul 2015Series B$13.5M
- Sep 2012Series A$7M
Investors
NewSpring, Health Enterprise Partners, Stonehenge Capital, Mitsui Global Investment, Fidelis Capital, Redmont Capital
Tech stack
AccessibeAnimate.CssAnime.JsCloudflareCloudflare Bot ManagementFacebook Pixel
#12
Seed · Birmingham, Alabama$40.5Kraised▾
Seed · Birmingham, Alabama
Standalone ambulatory surgery center
Funding & investor landscape
$991.9Mtotal disclosed funding
22companies funded
60disclosed rounds
0rounds last 90 days
Most active investors
Notable founders
Keshav Singh
Founder · Yuva Biosciences
Thomas Shufflebarger
CEO · Children’s of Alabama
Chad Trull
CEO · HighFive Healthcare
Charles A Dasher
Co-CEO · One Nineteen GI ASC
Riley Orr
Co-CEO · One Nineteen GI ASC
Larry Taylor
Founder & CEO · Practice Partners in Healthcare
Scott Comas
CEO & President · Hygia Health Services
Donald R Scott
Co-Founder · Personal Best
Diane McReynolds
Co-Founder · Personal Best
Ralph Hungerpiller
CEO · Creek Leaf Wellness
Jason Alexander
CEO · St. Vincent's Health System
Ken Horton
Founder & President · NuTech
Prism market signals · United States · country-scoped Prism corpus, 13,358,462 docs
Market landscape — 10 sub-themes by coverage
Share of Healthcare coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
How many Healthcare companies are there in Birmingham, United States?
Radar tracks 106 indexable Healthcare companies headquartered in Birmingham, United States that meet our profile-completeness bar.
What is the total funding raised by Healthcare companies in Birmingham, United States?
The Healthcare companies in Birmingham, United States on this list have raised a combined $991.9M in disclosed equity funding across 22 funded companies.
Which is the highest-funded Healthcare company in Birmingham, United States?
Upstream is the highest-funded Healthcare company in Birmingham, United States, with $745M in disclosed equity funding.
How many Healthcare companies in Birmingham, United States are funded?
22 of the 106 Healthcare companies in Birmingham, United States on this list have disclosed at least one equity funding round.
How many Healthcare unicorns are there in Birmingham, United States?
None of the Healthcare companies in Birmingham, United States on this list currently has a disclosed valuation of $1B or more.
Who are the top investors in Birmingham, United States Healthcare companies?
The most active investors in Birmingham, United States Healthcare companies on this list include HHS, Innovation Depot, Comvest Partners, Grant Avenue Capital, Yukon Partners.
Rohit KhannaTrends & Stories
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.