Best Healthcare IT Companies in San Mateo, United States
The 40 best Healthcare IT companies in San Mateo, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Brightline.
Our analysis of 90 Healthcare IT companies
$11.7b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Healthcare IT companies in San Mateo
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Brightline Provider of telehealth platform for kids behavioural health | $212M | 49 mo ago | 142 142 → 229 (+61%) | 2019 | Giovanni Colella Co-Founder | ContentfulApple iCloud MailGoogle Workspace+26 | 14 patents Advanced LED lighting fixtures with motorized direction and AR integration for immersive experiences. | — |
| 2 | Notable Provider of a wearable device for capturing patient-doctor interaction | $116M | 58 mo ago | 217 217 → 249 (+15%) | 2017 | Pranay Kapadia Co-Founder & CEO | WebflowApple iCloud MailGoogle Workspace+21 | 5 patents Patents concentrated in computing, sensing & instrumentation | 1 launch |
| 3 | RapidAI Developer of clinical AI platform enhancing medical imaging and stroke care | $100M | 37 mo ago | 229 | 2012 | Greg Albers Co-Founder & Scientific Lead | HubSpot CMS HubAmazon Web ServicesHubSpot+27 | — | — |
| 4 | Doximity Mobile networking platform for medical professionals | $82M | 148 mo ago | 977 977 → 914 (-6%) | 2011 | Nate Gross Md Co-Founder & Chief Strategy Officer | Apple iCloud MailGoogle WorkspaceSalesforce+22 | 23 patents Integrated telehealth communication platform with audio/video calls, language interpretation, and caller verification | 2 launchs |
| 5 | MORE Health Provider of cloud-based platform providing cross-border medical consulting | $78M | 89 mo ago | 56 | 2011 | Bo Hu Co-Founder & CTO | Apple iCloud MailGoogle WorkspaceNode.js+17 | — | — |
| 6 | Carta Healthcare Provider of an AI platform for clinical data management solutions 74Growth top 22%Funding top 25%Talent top 28%Moat top 31% All 8 signals ▾Growthtop 22% Fundingtop 25% Talenttop 28% Moattop 31% Techtop 36% Markettop 49% Globalbottom 37% Newsbottom 21% Growth: Headcount 19 → 57 (+200%) across vintages · Web rank 10,000,000 → 5,000,000 YoY Funding: Raised $62.3M across 4 rounds · 4 rounds over 8 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 74/100 | $62M | 15 mo ago | 57 57 → 125 (+119%) | 2017 | — | Cart FunctionalityWordPressUptimeRobot+32 | — | 1 launch |
| 7 | PokitDok Online slot gaming site with easy wins and jackpot opportunities | $53M | 99 mo ago | 56 | 2011 | — | — | 84 patents Blockchain-enabled healthcare identity and dynamic document management platforms | — |
| 8 | Caption Care AI-powered diagnsotic tool for early heart failure detection | $53M | 77 mo ago | — | 2013 | Kilian Koepsell Co-Founder | WebflowSalesforcecore-js+15 | — | — |
| 9 | Apixio Provider of data connectivity and exchange solutions for the healthcare industry | $49M | 97 mo ago | 41 | 2009 | David Pierre CEO | WordPressApple iCloud MailGoogle Workspace+48 | 98 patents Healthcare data analytics and workflow automation for patient outcomes, risk and record management | — |
| 10 | Lumiata Provider of AI-based patient care optimization platform for healthcare providers | $47M | 67 mo ago | 16 | 2013 | — | — | — | — |
| 11 | Human API Provider of API platform for health data integration | $37M | 70 mo ago | 62 | 2013 | — | SentryAtlassian StatuspageZendesk+16 | — | — |
| 12 | Epocrates Clinical decision support tool providing continually updated medical content for clinicians | $35M | 288 mo ago | 417 | 1998 | Richard Fiedotin Co-Founder | SalesforceJavaMUI+22 | 9 patents Clinical decision support and electronic prescription renewal platform for physicians. | — |
| 13 | Luminai Artificial intelligence based platform offering internal workflow automation solutions 62Funding top 27%Growth top 28%News top 29%Tech top 35% All 9 signals ▾Fundingtop 27% Growthtop 28% Newstop 29% Techtop 35% Talenttop 38% Moattop 39% AItop 45% Globalbottom 37% Marketbottom 29% Funding: Raised $24.1M across 3 rounds · 3 rounds over 6 yrs (0.5/yr) Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 62/100 | $24M | 4 mo ago | 9 | 2019 | Dmitry Dolgopolov Co-Founder | WebflowThree.jsAmazon Web Services+17 | — | — |
| 14 | Chooch AI-powered computer vision solutions | $23M | 45 mo ago | — | 2015 | Emrah Gultekin Co-Founder & Chairman | WordPressMySQLPHP+27 | — | — |
| 15 | Health Fidelity Healthcare cloud and smart platform enabling interoperability and data transformation | $19M | 72 mo ago | 73 | 2011 | — | — | — | — |
| 16 | iScribe A healthcare technology company that had developed mobile, handheld, wireless electronic prescribing… | $17M | 304 mo ago | — | 1999 | David Levinson CEO & President | — | — | — |
| 17 | Edifice Health Manufacturer of systemic chronic inflammation (SCI) test system | $14M | 64 mo ago | 8 | 2018 | David Furman Founder | — | — | — |
| 18 | Boost Developer of software for managing behavioral health practice administrative workflows 45Funding top 36%Patents bottom 48%Tech bottom 46%Talent bottom 45% All 6 signals ▾Fundingtop 36% Patentsbottom 48% Techbottom 46% Talentbottom 45% Innovationbottom 44% Globalbottom 43% Funding: Raised $10.9M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Patents: 12 patents matched (strict assignee match) · Latest publication 2015 rank vs industry peers · Fliar Intelligence Index 45/100 | $11M | 5 mo ago | — | 2019 | Lani Fritts CEO | WixSentryBootstrap+11 | 11 patents Incentive/reward platforms, promotional product ordering, and sports data display systems | 1 award |
| 19 | Virti Provider an immersive learning platform that provides AI-driven soft skills training with interactive video… | $10M | 62 mo ago | 9 | 2017 | Alexander Young Founder | WordPressMySQLPHP+29 | — | — |
| 20 | Project Ronin Provider of decision support software for oncologists | $10M | — | 102 | 2014 | David B Agus Co-Founder | — | — | — |
| 21 | HealthCrowd AI and cloud-based communication platform for providers | $4M | 129 mo ago | 47 | 2011 | — | — | — | — |
| 22 | Heally Holistic telehealth platform offering alternative medicine, weight loss, and sexual health solutions | $2M | 86 mo ago | 21 | 2016 | Greg Rovner Co-Founder & CEO | RubyGoogle MapsBootstrap+22 | — | — |
| 23 | Storii Digital patient engagement tool for providers and patients | $479K | 110 mo ago | 7 | 2014 | Vitalij Kornijenko Co-founder & CTO | Cart FunctionalityShopifyYouTube+30 | — | — |
| 24 | Heka Health Online community and employee based wellness and health management tool for proffesioanls | $354K | 77 mo ago | 8 | 2015 | Tony Salah Founder & CEO | Wix eCommerceWixSentry+16 | — | — |
Top 12 Healthcare IT companies in San Mateo
#1
Series B · San Mateo, California · founded 2019 · 9 employees$24.1Mraised▾
Artificial intelligence based platform offering internal workflow automation solutions. It also assists users in creating multi-click processes and eliminates repetitive tasks.
- Apr 2026Series B$38M
- Mar 2022Series A$20.7M
- Oct 2020Seed$3.4M
- Aug 2020Seed—
#2
Series B · San Mateo, California · founded 2019$10.9Mraised▾
Developer of software for managing behavioral health practice administrative workflows. This platform integrates billing, scheduling, and compliance management tools to assist with revenue cycle operations. It provides automated systems for staff assignment, client intake, and claim processing to facilitate practice management. The software includes features for workflow automation and data organization to support operational tasks within clinical environments.
- Mar 2026Series B$10.9M
#3
Series B · San Mateo, California · founded 2017 · 57 employees$62.3Mraised▾
Provider of an AI platform for clinical data management solutions. The platform offers tools for data capture, workflow management, and abstraction to deliver insights. It assists with registry data collection, improves workflow, and ensures data submission quality. The platform also supports research by streamlining screening and refining patient groups.
- May 2025Series B$18.2M
- Jun 2023Series B$25M
- Nov 2022Series B$20M
- Apr 2021Series A$17.3M
#4
Series C · San Mateo, California · founded 2019 · 142 employees$212Mraised▾
Provider of telehealth platform for kids behavioural health. It is a pediatric mental health care provider focused on delivering therapy, psychiatry, and behavioral health support for children, teens, and the families. The service is designed to address a range of mental health concerns, including depression, anxiety, ADHD, OCD, autism, and disruptive behaviors, with specialized programs and evidence-based treatments.
- Jul 2022Series C$10M
- Mar 2022Series C$105M
- Jun 2021Series B$72M
- Jun 2021Venture Debt$7M
#5
Series C · San Mateo, California · founded 2012 · 229 employees$100Mraised▾
Developer of clinical AI platform enhancing medical imaging and stroke care. The platform provides tools for neurovascular, hemorrhagic, and ischemic stroke assessment. It offers solutions for aneurysm tracking, cardiac and vascular analysis, and radiology workflows. The platform aims to deliver real-time insights for confident decision-making and streamlined resource allocation.
- Jul 2023Series C$75M
- Sep 2020Series B$25M
#6
Series B · San Mateo, California · founded 2017 · 217 employees$116.5Mraised▾
Provider of a wearable device for capturing patient-doctor interaction. It is an AI-powered voice interface to capture patient-doctor interaction, access data from EHR's, record lab tests, prescriptions, referrals to create an EHR for the physician. The device can also track stress, effectiveness, malpractices, billings of the physician.
- Nov 2021Series B$100M
- Sep 2018Series A$13.5M
- May 2018Seed$3M
#7
Series A · San Mateo, California · founded 2015$22.9Mraised▾
AI-powered computer vision solutions. It provides tools that help businesses analyze visual data in real time to improve decision making and automate workflows. The platform supports applications including security monitoring, healthcare imaging, and industrial automation.
- Nov 2022Series A$20.1M
- May 2022Grant (prize money)$100K
- Nov 2020Series A$20.1M
- Apr 2019Seed$2.8M
#8
Acquired · San Mateo, California · founded 2013 · 16 employees$47Mraised▾
Lumiata is a provider of AI-based patient care optimization platform for healthcare providers. The platform collects massive amounts of medical science data and organizes it in interconnected graphs to produce key insights for patient care. Health providers can run anonymized medical records, genetic information, or sensor data through Lumiata’s graph to receive hyper-personalized predictions and recommendations for individual patients. The company's flagship product, the Lumiata Risk Matrix provides the current and evolving risk of each individual within a population through highly precise, time-based predictions coupled with medical reasoning.
- Jan 2021Series B$14M
- Jul 2018Series B$11M
- Nov 2017Series B$3M
- Mar 2016Series B$10M
#9
Series C · San Mateo, California · founded 2011 · 56 employees$77.8Mraised▾
Provider of cloud-based platform providing cross-border medical consulting. The company provides instant diagnosis and treatment proposals for patients from around the world. The company also provides a collaborative platform for the providers and a secure environment to protect patients' privacy.
- Apr 2019Series C$74.5M
- Apr 2015Series A$3.3M
- Jun 2014Conventional Debt$410K
#10
Acquired · San Mateo, California · founded 2011 · 56 employees$53.3Mraised▾
Online slot gaming site with easy wins and jackpot opportunities. This platform is a popular destination for slot enthusiasts, offering a variety of games with the potential for significant jackpot wins. Users can download the application for convenient access. The site emphasizes user experience, providing a platform where players can easily engage with their favorite slot games. It focuses on delivering an accessible and potentially rewarding gaming experience. Features include account registration, login, a shopping cart, and customer support. The platform uses cookies and similar technologies to enhance user experience, including personalized advertising options. It also offers options for users to manage their privacy settings. The site provides a range of slot games, including those with progressive jackpots, and emphasizes ease of use and accessibility for players of all levels.
- May 2018Series B$4M
- Mar 2017Series B—
- Feb 2017Series B$5M
- Feb 2016Series B—
#11
Acquired · San Mateo, California · founded 2009 · 41 employees$49.4Mraised▾
Provider of data connectivity and exchange solutions for the healthcare industry. The company offers a platform and network designed to deliver solutions across the healthcare ecosystem. It facilitates health data retrieval, release of information, and real-world data connectivity. The business also provides linkage and privacy solutions, along with data transformation services.
- Jul 2018Series D$5M
- May 2016Series D$19.3M
- Jun 2014Series C$13.5M
- Nov 2013Series C$2.5M
#12
Public · San Mateo, California · founded 2011 · 977 employees$81.8Mraised▾
Mobile networking platform for medical professionals. Physicians can connect with other healthcare professionals, collaborate on patient treatment, grow their practices, and discover new career opportunities. Also allows hospitals to find doctors and recruiters. It offers information on residency training programs in collaboration.
- Apr 2014Series C$54M
- Oct 2012Series B$17.1M
- Mar 2011Series A$10.8M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Healthcare IT coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in the United States
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,843 United States-affiliated papers.
- Design Intelligence421
- Harvard University383
- Johns Hopkins University295
- University of North Carolina at Chapel Hill206
- University of Washington173
- Health care9→240
- Wearable computer6→129
- Health informatics25→140
- Remote patient monitoring11→76
- Informatics10→60
- Health care36→766
- Health informatics113→495
- Psychological intervention20→320
- Public health34→290
- Intervention (counseling)5→193
- Health care98→1170
- Health informatics213→712
- Public health73→525
- Psychological intervention26→368
- Health administration110→363
Where digital health is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing digital health patents in the United States
United States digital health patent filing is accelerating — 2,575 filings from 1,291 assignees (2016–2025), led by Boeing, Honeywell INT, Advanced Neuromodulation Systems; annual filings 173→270.
- Boeing150
- Honeywell INT129
- Advanced Neuromodulation Systems96
- General Electric91
- Hamilton Sundstrand67
- IBM65
- OTIS Elevator50
- Sikorsky Aircraft49
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.